Compounds > adenine

adenine and emtricitabine, tenofovir disoproxil fumarate drug combination

adenine has been researched along with emtricitabine, tenofovir disoproxil fumarate drug combination in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (19.23)29.6817
2010's17 (65.38)24.3611
2020's4 (15.38)2.80

Authors

AuthorsStudies
Hidalgo, A; Palacios, R; Rivero, A; Santos, J; Terrón, A1
del Arco, A; Gálvez, MC; Gutiérrez-Ravé, V; Hidalgo, C; Lozano, F; Muñoz, L; Palacios, R; Ríos, MJ; Rivero, A; Santos, J1
Hughes, B1
Barr, JR; Cong, ME; Folks, TM; García-Lerma, JG; Hanson, DL; Heneine, W; Holder, A; Kuklenyik, Z; Lipscomb, J; Martin, A; Masciotra, S; Mitchell, J; Otten, R; Pau, CP; Paxton, L; Youngpairoj, AS; Zheng, Q1
Bateman, C1
Brüning, A; Burger, P; Gingelmaier, A; Mylonas, I1
Fidler, S; Fisher, M; McCormack, S1
De Clercq, E1
Haire, B; Jordens, CF; Kaldor, J1
Grabczewska, E; Olczak, A1
Adams, DR; Butler, K; Cong, ME; Garcia-Lerma, JG; Hanson, D; Hendry, RM; Heneine, W; Kersh, EN; Luo, W; McNicholl, JM; Youngpairoj, AS; Zheng, Q1
Holmes, D1
Herold, BC; Kiser, PF; Mesquita, PM1
Beck, EJ; Brettle, R; Gazzard, B; Gompels, M; Johnson, M; Mandalia, S; Pozniak, A; Sangha, R; Schwenk, A; Taylor, S; Walsh, J; Wilkins, E; Williams, I; Youle, M1
Hawkes, N1
Reinke, T1
Brown, K; Cunningham, D; De Wit, S; Eron, JJ; Hufkens, V; Jezorwski, J; Lathouwers, E; Opsomer, M; Orkin, C; Petrovic, R; Post, FA; Pulido, F; Van Landuyt, E1
Armstrong, WS; Del Rio, C1
Anderson, PL; Brainard, DM; Brinson, C; Callebaut, C; Clarke, A; Coll, P; Collins, SE; Das, M; De Wet, JJ; DeJesus, E; Ebrahimi, R; Grant, RM; Hare, CB; Jessen, H; Mathias, A; Mayer, KH; McCallister, S; Molina, JM; Mounzer, KC; Post, FA; Ruane, PJ; Thompson, MA; Wong, P; Zhong, L1
Benet, LZ; Gandhi, M; Koss, CA; Kuncze, K; Louie, A; Okochi, H; Phung, N; Spinelli, MA; Tallerico, RM; Zhang, K1
Carneiro, PB; D'Angelo, AB; Grov, C; Johnson, J; Westmoreland, DA1

Reviews

2 review(s) available for adenine and emtricitabine, tenofovir disoproxil fumarate drug combination

ArticleYear
Tenofovir: quo vadis anno 2012 (where is it going in the year 2012)?
    Medicinal research reviews, 2012, Volume: 32, Issue:4

    Topics: Adenine; Anti-HIV Agents; Deoxycytidine; Drug Combinations; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; HIV; HIV Infections; Humans; Organophosphonates; Organophosphorus Compounds; Tenofovir

2012
[HIV preexposure prophylaxis].
    Przeglad epidemiologiczny, 2012, Volume: 66, Issue:1

    Topics: Adenine; Administration, Oral; Animals; Anti-HIV Agents; Chemoprevention; Clinical Trials as Topic; Deoxycytidine; Drug Combinations; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Female; HIV Infections; Humans; Male; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Tenofovir

2012

Trials

2 trial(s) available for adenine and emtricitabine, tenofovir disoproxil fumarate drug combination

ArticleYear
Week 96 efficacy and safety results of the phase 3, randomized EMERALD trial to evaluate switching from boosted-protease inhibitors plus emtricitabine/tenofovir disoproxil fumarate regimens to the once daily, single-tablet regimen of darunavir/cobicistat/
    Antiviral research, 2019, Volume: 170

    Topics: Adenine; Adult; Aged; Alanine; Anti-HIV Agents; Cobicistat; Darunavir; Drug Combinations; Drug Substitution; Emtricitabine; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Protease Inhibitors; Sustained Virologic Response; Tablets; Tenofovir; Treatment Outcome; Viral Load

2019
Emtricitabine and tenofovir alafenamide vs emtricitabine and tenofovir disoproxil fumarate for HIV pre-exposure prophylaxis (DISCOVER): primary results from a randomised, double-blind, multicentre, active-controlled, phase 3, non-inferiority trial.
    Lancet (London, England), 2020, 07-25, Volume: 396, Issue:10246

    Topics: Adenine; Adult; Anti-HIV Agents; Double-Blind Method; Emtricitabine; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Europe; Female; HIV Infections; HIV-1; Homosexuality, Male; Humans; Male; North America; Placebos; Pre-Exposure Prophylaxis; Prevalence; Safety; Sexual and Gender Minorities; Tenofovir; Treatment Outcome

2020

Other Studies

22 other study(ies) available for adenine and emtricitabine, tenofovir disoproxil fumarate drug combination

ArticleYear
[Simply convincing. New fixed combination for HIV therapy].
    MMW Fortschritte der Medizin, 2005, Apr-25, Volume: 147 Spec No 1

    Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Clinical Trials as Topic; Deoxycytidine; Drug Administration Schedule; Drug Combinations; Drug Resistance, Viral; Emtricitabine; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; HIV Infections; Humans; Organophosphonates; Organophosphorus Compounds; Patient Compliance; Practice Guidelines as Topic; Survival Rate; Tenofovir

2005
Minor emtricitabine intolerance in treatment-stable patients switched from tenofovir/lamivudine to a fixed-dose combination of tenofovir/emtricitabine (Truvada).
    The Journal of antimicrobial chemotherapy, 2008, Volume: 61, Issue:2

    Topics: Adenine; Deoxycytidine; Drug Combinations; Drug Therapy, Combination; Emtricitabine; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Humans; Lamivudine; Organophosphonates; Organophosphorus Compounds; Sleep Initiation and Maintenance Disorders; Tenofovir

2008
Effectiveness and safety of simplification from tenofovir-lamivudine (TDF-3TC) to tenofovir-emtricitabine (TDF-FTC) co-formulation (Truvada) in virologically suppressed HIV-infected patients on HAART.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2009, Volume: 28, Issue:4

    Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Central Nervous System; Cohort Studies; Creatinine; Deoxycytidine; Drug Combinations; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Female; HIV Infections; HIV-1; Humans; Kidney; Lamivudine; Male; Metabolic Clearance Rate; Middle Aged; Organophosphonates; Organophosphorus Compounds; Retrospective Studies; Risk Factors; RNA, Viral; Tenofovir; Viral Load

2009
Generic Truvada approved.
    AIDS patient care and STDs, 2009, Volume: 23, Issue:5

    Topics: Adenine; Anti-HIV Agents; Deoxycytidine; Drug Approval; Drug Combinations; Drugs, Generic; Emtricitabine; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; HIV Infections; Humans; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Tenofovir; United States; United States Food and Drug Administration

2009
Tapping into combination pills for HIV.
    Nature reviews. Drug discovery, 2009, Volume: 8, Issue:6

    Topics: Adenine; Anti-Retroviral Agents; Deoxycytidine; Drug Combinations; Drug Industry; Efavirenz, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; HIV Infections; Humans; Organophosphonates; Organophosphorus Compounds; Oxazines

2009
Single-tablet Quad regimen achieves high rate of virologic suppression.
    AIDS patient care and STDs, 2010, Volume: 24, Issue:3

    Topics: Adenine; Anti-HIV Agents; Atazanavir Sulfate; CD4 Lymphocyte Count; Clinical Trials, Phase II as Topic; Cytochrome P-450 CYP3A Inhibitors; Deoxycytidine; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Efavirenz, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; HIV Infections; HIV-1; Humans; Multicenter Studies as Topic; Oligopeptides; Organophosphonates; Organophosphorus Compounds; Oxazines; Pyridines; Quinolones; Randomized Controlled Trials as Topic; Ritonavir; Treatment Outcome; Viral Load

2010
Intermittent prophylaxis with oral truvada protects macaques from rectal SHIV infection.
    Science translational medicine, 2010, Jan-13, Volume: 2, Issue:14

    Topics: Adenine; Administration, Oral; Animals; Deoxycytidine; Drug Combinations; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Kinetics; Leukocytes, Mononuclear; Macaca; Organophosphonates; Organophosphorus Compounds; Proportional Hazards Models; Rectum; Research Design; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Tenofovir; Time Factors; Treatment Outcome; Viral Load

2010
Findings in humanized-mouse model suggest benefit of further studies in HIV pre-exposure prophylaxis.
    Expert review of clinical immunology, 2010, Volume: 6, Issue:2

    Topics: Adenine; Animals; Anti-HIV Agents; Bone Marrow Transplantation; Clinical Trials as Topic; Deoxycytidine; Disease Models, Animal; Drug Combinations; Emtricitabine; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; HIV; HIV Antibodies; HIV Infections; Humans; Infection Control; Liver Transplantation; Mice; Occupational Exposure; Organophosphonates; Organophosphorus Compounds; Tenofovir; Thymus Gland; Transplantation Chimera

2010
Still a long wait for approved HIV-protective gel.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2010, Sep-07, Volume: 100, Issue:9

    Topics: Adenine; Antiviral Agents; Deoxycytidine; Drug Approval; Drug Combinations; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Female; HIV Infections; Humans; Organophosphonates; Organophosphorus Compounds; Technology Transfer; Tenofovir; Vaginal Creams, Foams, and Jellies

2010
Early end for FEM-PrEP HIV prevention trial.
    AIDS patient care and STDs, 2011, Volume: 25, Issue:6

    Topics: Adenine; Administration, Oral; Anti-HIV Agents; Deoxycytidine; Drug Combinations; Emtricitabine; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Female; HIV Infections; Humans; Kenya; Organophosphonates; Organophosphorus Compounds; Patient Compliance; Randomized Controlled Trials as Topic; South Africa; Tanzania; Tenofovir

2011
The HIV reverse transcriptase inhibitor tenofovir induces cell cycle arrest in human cancer cells.
    Investigational new drugs, 2012, Volume: 30, Issue:4

    Topics: Adenine; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cytostatic Agents; Deoxycytidine; DNA Breaks, Double-Stranded; Doxorubicin; Drug Combinations; Drug Screening Assays, Antitumor; Emtricitabine; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Female; Histones; HIV Reverse Transcriptase; Humans; Organophosphonates; Organophosphorus Compounds; Ovarian Neoplasms; Reverse Transcriptase Inhibitors; Tenofovir; Time Factors

2012
The British HIV Association/British Association for Sexual Health and HIV Position Statement on pre-exposure prophylaxis in the UK.
    International journal of STD & AIDS, 2012, Volume: 23, Issue:1

    Topics: Adenine; Anti-HIV Agents; Deoxycytidine; Drug Combinations; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Female; HIV Infections; Humans; Organophosphonates; Organophosphorus Compounds; Tenofovir; United Kingdom

2012
How good is "good enough"? The case for varying standards of evidence according to need for new interventions in HIV prevention.
    The American journal of bioethics : AJOB, 2012, Volume: 12, Issue:6

    Topics: Adenine; Administration, Intravaginal; Administration, Oral; Anti-HIV Agents; Deoxycytidine; Drug Combinations; Emtricitabine; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Ethical Analysis; Ethical Theory; Ethics, Research; Evidence-Based Medicine; Female; Gels; Guidelines as Topic; Health Services Accessibility; Health Services Needs and Demand; HIV Infections; Homosexuality, Male; Humans; Male; Organophosphonates; Organophosphorus Compounds; Primary Prevention; Randomized Controlled Trials as Topic; Research Subjects; Sex Work; Tenofovir; Therapeutic Equipoise; United States; United States Food and Drug Administration

2012
Reduced inflammation and CD4 loss in acute SHIV infection during oral pre-exposure prophylaxis.
    The Journal of infectious diseases, 2012, Sep-01, Volume: 206, Issue:5

    Topics: Adenine; Alanine; Animals; Anti-HIV Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cytokines; Deoxycytidine; Drug Combinations; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Longitudinal Studies; Macaca mulatta; Male; Organophosphorus Compounds; Reverse Transcriptase Polymerase Chain Reaction; RNA, Viral; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Statistics, Nonparametric; Tenofovir; Viremia

2012
FDA paves the way for pre-exposure HIV prophylaxis.
    Lancet (London, England), 2012, Jul-28, Volume: 380, Issue:9839

    Topics: Adenine; Anti-HIV Agents; Antiviral Agents; Deoxycytidine; Drug Combinations; Emtricitabine; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; HIV Infections; Humans; Organophosphonates; Organophosphorus Compounds; Primary Prevention; Tenofovir; United States; United States Food and Drug Administration

2012
A perspective on progress and gaps in HIV prevention science.
    AIDS research and human retroviruses, 2012, Volume: 28, Issue:11

    Topics: Adenine; Administration, Oral; Administration, Topical; Anal Canal; Anti-HIV Agents; Chemoprevention; Deoxycytidine; Drug Combinations; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Female; HIV Infections; Humans; Immunity, Innate; Male; Medication Adherence; Mouth Mucosa; Mucous Membrane; Organophosphonates; Organophosphorus Compounds; Sexual Partners; Tenofovir; Vagina; Vaginal Creams, Foams, and Jellies

2012
Lower healthcare costs associated with the use of a single-pill ARV regimen in the UK, 2004-2008.
    PloS one, 2012, Volume: 7, Issue:10

    Topics: Adenine; Adult; Anti-Retroviral Agents; CD4 Lymphocyte Count; Deoxycytidine; Drug Combinations; Efavirenz, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Female; Health Care Costs; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Oxazines; Proportional Hazards Models; United Kingdom; Viral Load

2012
FDA must publish data on safety and efficacy of prophylactic AIDS drug, court rules.
    BMJ (Clinical research ed.), 2013, Aug-19, Volume: 347

    Topics: Access to Information; Acquired Immunodeficiency Syndrome; Adenine; Anti-HIV Agents; Deoxycytidine; Drug Combinations; Drug Therapy, Combination; Emtricitabine; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Humans; Organophosphonates; Organophosphorus Compounds; Publishing; Tenofovir; United States; United States Food and Drug Administration

2013
Regimen Change: Gilead's TAF Drugs Toppling TDFs in HIV Treatment.
    Managed care (Langhorne, Pa.), 2017, Volume: 26, Issue:9

    Topics: Adenine; Alanine; Drug Therapy, Combination; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; HIV Infections; Humans; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Outcome

2017
How Much Are We Willing to Pay for Preexposure Prophylaxis in the United States?
    Annals of internal medicine, 2020, 05-05, Volume: 172, Issue:9

    Topics: Adenine; Alanine; Anti-HIV Agents; Cost-Benefit Analysis; Decision Making, Shared; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Health Services Accessibility; HIV Infections; Humans; Pre-Exposure Prophylaxis; Tenofovir; United States

2020
Tenofovir and emtricitabine concentrations in hair are comparable between individuals on tenofovir disoproxil fumarate versus tenofovir alafenamide-based ART.
    Drug testing and analysis, 2021, Volume: 13, Issue:7

    Topics: Adenine; Anti-HIV Agents; Chromatography, High Pressure Liquid; Cobicistat; Dose-Response Relationship, Drug; Emtricitabine; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Hair; Hair Analysis; HIV Infections; Humans; Ritonavir; Tandem Mass Spectrometry; Tenofovir; Tissue Distribution

2021
Why Are Patients Switching from Tenofovir Disoproxil Fumarate/Emtricitabine (Truvada) to Tenofovir Alafenamide/Emtricitabine (Descovy) for Pre-Exposure Prophylaxis?
    AIDS patient care and STDs, 2021, Volume: 35, Issue:8

    Topics: Adenine; Alanine; Anti-HIV Agents; Cohort Studies; Emtricitabine; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; HIV Infections; Humans; Male; Pre-Exposure Prophylaxis; Tenofovir

2021