Compounds > adenine

adenine and duocarmycin sa

adenine has been researched along with duocarmycin sa in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boger, DL; Hedrick, MP; Stauffer, F1
Carloni, P; Rothlisberger, U; Spiegel, K1
Boger, DL; Hwang, I; Kastrinsky, DB; Shiga, F; Tichenor, MS; Trzupek, JD1
Asao, T; Hartley, JA; Kiakos, K; Lee, M; McHugh, PJ; Sato, A1

Other Studies

4 other study(ies) available for adenine and duocarmycin sa

ArticleYear
Substituent effects within the DNA binding subunit of CBI analogues of the duocarmycins and CC-1065.
    Bioorganic & medicinal chemistry letters, 2001, Aug-06, Volume: 11, Issue:15

    Topics: Adenine; Alkylation; Antibiotics, Antineoplastic; Binding Sites; DNA; DNA Adducts; Duocarmycins; Humans; Indoles; Inhibitory Concentration 50; Leucomycins; Nucleic Acid Conformation; Pyrroles; Pyrrolidinones; Tumor Cells, Cultured

2001
Duocarmycins binding to DNA investigated by molecular simulation.
    The journal of physical chemistry. B, 2006, Mar-02, Volume: 110, Issue:8

    Topics: Adenine; Algorithms; Alkylation; Antineoplastic Agents, Alkylating; Base Sequence; Binding Sites; Catalysis; Computer Simulation; DNA; Duocarmycins; Hydrogen Bonding; Indoles; Molecular Conformation; Oligonucleotides; Pyrroles

2006
Asymmetric total synthesis of (+)- and ent-(-)-yatakemycin and duocarmycin SA: evaluation of yatakemycin key partial structures and its unnatural enantiomer.
    Journal of the American Chemical Society, 2006, Dec-13, Volume: 128, Issue:49

    Topics: Adenine; Alkylating Agents; Alkylation; Antibiotics, Antineoplastic; Base Pairing; Base Sequence; DNA; Duocarmycins; Hydrogen-Ion Concentration; Indoles; Kinetics; Models, Chemical; Pyrroles; Stereoisomerism; Streptomyces; Temperature

2006
DNA sequence selective adenine alkylation, mechanism of adduct repair, and in vivo antitumor activity of the novel achiral seco-amino-cyclopropylbenz[e]indolone analogue of duocarmycin AS-I-145.
    Molecular cancer therapeutics, 2007, Volume: 6, Issue:10

    Topics: Adenine; Alkylating Agents; Alkylation; Animals; Antineoplastic Agents; CHO Cells; Cricetinae; Cricetulus; DNA Adducts; DNA Damage; DNA Repair; Drug Evaluation, Preclinical; Duocarmycins; Humans; Indoles; Mice; Molecular Structure; Pyrroles; Saccharomyces cerevisiae; Structure-Activity Relationship; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2007