adenine and didanosine

adenine has been researched along with didanosine in 110 studies

Research

Studies (110)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	6 (5.45)	18.2507
2000's	93 (84.55)	29.6817
2010's	11 (10.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Balzarini, J; Bergamini, A; Calio, R; De Clercq, E; Milanese, G; Pauwels, R; Perno, CF; Rocchi, G; Yarchoan, R	1
Broder, S; Kageyama, S; Mitsuya, H; Yarchoan, R	1
Ahmed, PS; Brennan, TM; Bridges, CG; Casara, P; Hornsperger, JM; Navé, JF; Taylor, DL; Tyms, AS	1
Anderson, BD; Ho, NF; Singhal, D	1
Merigan, TC; Palmer, S; Shafer, RW	1
Crabbs, C; Greenhouse, J; Lewis, MG; Lisziewicz, J; Lori, F; Silvera, P; Tinelli, C; Varga, G; Wagner, W; Xu, J; Yalley-Ogunro, J; Zinn, DE	1
Cheng, B	1
Birkus, G; Cihlar, T; Greenwalt, DE; Hitchcock, MJ	1
Coull, JJ; Drusano, GL; Hossain, MM; Margolis, DM	1
Dusak, BA; Goodwin, SD; Kuritzkes, DR; Rooney, JF; Skowron, G; Squires, KE; Stevens, M; Thompson, MA; Tolson, JM; Yuen, GJ	1
Bates, M; Chappey, C; Hellmann, NS; Maroldo, L; Parkin, N; Petropoulos, CJ	1
Chou, S; Murphy, MD; O'Hearn, M	1
Bacheler, L; Erickson-Viitanen, S; Gallagher, K; Garber, S; Geleziunas, R; Otto, MJ; Schinazi, RF; Shi, G; Wu, JT; Zhang, H	1
Fridland, A; Robbins, BL; Rodman, JH; Wilcox, CK	1
Callens, S; Colebunders, R; De Schacht, C; Huyst, V	1
Bassetti, D; Bassetti, M; Ciravegna, BW; Di Biagio, A; Ferrazin, A; Rosso, R	1
Kirian, MA; Pecora Fulco, P	1
Blanchard, JN; Canas, A; King, K; Lonergan, JT; Wohlfeiler, M	1
Abad, S; Blanche, P; Chauvelot-Moachon, L; Daniel, N; Kélaïdi, C; Nazal, EM; Rollot, F; Saba, M	1
Cunningham, CK; McKinney, RE	1
Boyle, BA	1
Fridland, A; Olson, L; Ray, AS	1
Carter, M	1
Gazzard, B; Mandalia, S; Nelson, M; Pillay, D; Pozniak, A; Winston, A	1
Barrios, A; García-Benayas, T; González-Lahoz, J; Soriano, V	1
Burger, D; Clotet, B; Grassi, J; Juan, M; Masmitjà, E; Moltó, J; Negredo, E; Paredes, R; Pruvost, A; Puig, J; Ribera, E; Ruiz, L; Viciana, P	1
Gutiérrez, F; Masiá, M; Padilla, S; Pascual, J; Ramos, JM	2
Burger, D; Clotet, B; Galindos, MJ; Gel, S; Miralles, C; Moltó, J; Muñoz-Moreno, JA; Negredo, E; Pedrol, E; Puig, J; Ribera, E; Rodriguez Fumaz, C; Rodríguez, E; Ruiz, L; Viciana, P; Videla, S	1
Bates, M; Chappey, C; Clair, MS; Fisher, R; Lanier, ER; Parkin, N; Ross, L; Tisdale, M	1
Fung, HB; Guo, Y	1
Fulco, PP; Higginson, RT; Kirian, MA	1
Aguero, J; Corral, A; de Mendoza, C; Gallego, O; Martin-Carbonero, L; Soriano, V	1
Auclair, M; Capeau, J; Caron, M; Kornprobst, M; Lagathu, C; Lombès, A; Walker, UA	1
Boeri, E; Castagna, A; Clementi, M; Fusetti, G; Galli, A; Gianotti, N; Lazzarin, A; Salpietro, S; Seminari, E	1
Anderson, PL; Becker, SL; Kakuda, TN	1
Blanco, JL; Gatell, JM; Laguno, M; León, A; Mallolas, J; Martinez, E; Pumarola, T	1
Sax, PE	1
Chaix, ML; Delaugerre, C; Peytavin, G; Roudiere, L; Rouzioux, C; Viard, JP	1
Dalmau, D; Ferrer, E; Gatell, JM; Iniguez, D; Knobel, H; Leon, A; Niubo, J; Podzamczer, D; Polo, C; Ruiz, I	1
Barreiro, P; Barrios, A; Blanco, F; Clotet, B; Cooper, D; Domingo, P; Garcia-Benayas, T; Gil, P; Gonzalez-Lahoz, J; Labarga, P; Maida, I; Martín-Carbonero, L; Negredo, E; Núñez, M; Rendón, A; Sambeat, MA; Sánchez-Conde, M; Santos, J; Soriano, V	1
Abraira, V; Antela, A; Casado, JL; Dronda, F; Gutiérrez, C; López, D; Moreno, A; Moreno, S; Pérez-Elías, MJ; Rodríguez, MA	1
Benech, H; Clotet, B; García, E; Grassi, J; Grau, E; Moltó, J; Negredo, E; Pruvost, A; Puig, J; Theodoro, F	1
Margot, NA; Miller, MD	1
Bower, M; Gazzard, B; Mandalia, S; Nelson, M; Tung, MY	1
Girard, PM; Lacombe, K; Meynard, JL; Pacanowski, J; Trylesinski, A	1
Boffito, M; Gazzard, B; Hand, J; Maitland, D; Mandalia, S; Moyle, G; Nelson, M	1
Bonjoch, A; Clotet, B; Negredo, E; Paredes, R; Puig, J	1
Maitland, D; Moyle, GJ; Waters, L	1
Biglia, A; Blanco, JL; De Lazzari, E; Gatell, JM; Laguno, M; Larrousse, M; León, A; Lonca, M; Mallolas, J; Martinez, E; Milincovic, A; Pumarola, T	1
Battegay, M; Cavassini, M; Elzi, L; Furrer, H; Gayet-Ageron, A; Hirschel, B; Karrer, U; Ledergerber, B; Russotti, M; Schmid, P; Speck, RF; Weber, R	1
Chen, SS; Cheng, AK; Flaherty, JF; Kaul, S; Kearney, BP; Sayre, JR	1
Asensi, V; Barrios, A; Clotet, B; Domingo, P; Estrada, V; Labarga, P; Morales, D; Negredo, E; Santos, J; Soriano, V	1
Diaz, RS	1
Cardellach, F; Casademont, J; Clotet, B; Garrabou, G; Infante, AB; López, S; Miró, O; Negredo, E; Puig, J; Ramos, X; Ruiz, L; Sanjurjo, E	1
Coco, J; DeJesus, E; Grinsztejn, B; Johnson, M; Lazzarin, A; Lichtenstein, K; McLaren, C; Odeshoo, L; Rightmire, A; Rodriguez, C; Wirtz, V	1
Côté, HC; Gadawski, I; Harrigan, PR; Harris, M; Hogg, R; Magil, AB; Montaner, JS; Scarth, BJ; Wang, N; Werb, R; Yip, B; Yu, E; Zalunardo, N	1
Barreiro, P; Soriano, V	1
Balestre, E; Boucher, S; Capdepont, S; Dabis, F; Dupon, M; Fleury, H; Masquelier, B; Thiébaut, R	1
Armon, C; Baker, RK; Holmberg, SD; Moorman, AC; Weidle, PJ; Wood, KC; Young, B	1
Barreiro, P; Barrios, A; Blanco, F; García-Benayas, T; González-Lahoz, J; Maida, I; Rendón, AL; Rivas, P; Rodríguez-Novóa, S; Soriano, V	1
Bacheler, L; Koontz, D; Mellors, JW; Parikh, UM	1
Anderson, PL; Kakuda, TN	1
Amiel, C; Guessant, S; Kara, A; Lebrette, MG; Marechal, Eda S; Pialoux, G; Quercia, R; Renaud, S; Schneider, V; Thevenet, S	1
Hussain, S; Khayat, A; Rathore, MH; Tolaymat, A	1
Brenner, BG; Doualla-Bell, F; Essex, M; Frankel, F; Moisi, DD; Ntemgwa, M; Oliveira, M; Wainberg, MA	1
Cirino, CM; Kan, VL	1
Alvarez, ML; Cihlar, T; Cordobilla, B; Domingo, JC; Domingo, P; Giralt, M; Guallar, J; López-Dupla, M; Sánchez de la Rosa, R; Saumoy, M; Torres, F; Vidal, F; Villarroya, F	1
Bongiovanni, M; Tordato, F	1
Bogner, J; Claas, GJ; Goebel, FD; Jülg, B	1
Antinori, A; Antonucci, F; Barreiro, P; Carosi, G; De Silvestri, A; El Hamad, I; Ladisa, N; Lapadula, G; Maggiolo, F; Mandalia, S; Maserati, R; Migliorino, G; Pierotti, P; Sighinolfi, L; Soriano, V; Suter, F; Torti, C	1
Maggiolo, F; Ripamonti, D; Suter, F	1
Anastos, K; Cohen, M; Cole, S; Hessol, NA; Justman, J; Kaplan, RC; Lu, D; Shi, Q; Tien, PC; Vigen, C; Young, M	1
Gripshover, B; Gupta, S; Hammond, SP; Hatano, H; Hu, Z; Kalayjian, RC; Kuritzkes, DR; Smith, D; Whitcomb, J; Wild, M	1
Crane, HM; Harrington, RD; Kestenbaum, B; Kitahata, MM	1
Clotet, B; Girard, PM; Negredo, E; Neubacher, D; Youle, M	1
Ball, C; Hawkins, S	1
Bae, AS; Borroto-Esoda, K; Goodman, D; Margot, NA; Miller, MD; Svarovskaia, ES; Waters, JM; Zhong, L	1
Ainsworth, J; Booth, C; Bradshaw, D; Geretti, AM; Malik, S; Pattery, T; Van Houtte, M; Waters, A	1
Burger, DM; Droste, JA; Lange, JM; Lowe, SH; Prins, JM; Reiss, P; Repping, S; van der Veen, F; van Leeuwen, E	1
Abeli, C; Antinori, A; Bongiovanni, M; Capetti, A; Castagna, A; Chiesa, E; Cicconi, P; d'Arminio Monforte, A; de Luca, A; di Biagio, A; Gatti, F; Gianotti, N; Marconi, P; Matti, A; Mussini, C; Nasta, P; Tirelli, V; Torti, C; Zaccarelli, M	1
Doerries, R; Drechsler, H; Gass, A; Hardmeier, M; Kuhle, J; Mehling, M; Ruegg, S	1
Ananworanich, J; Côté, HC; Hill, A; Hirschel, B; Jupimai, T; Kerr, SJ; Laopraynak, N; Nuesch, R; Ruxrungtham, K; Saenawat, S	1
Barreiro, P; Corral, A; de Mendoza, C; Garrido, C; González-Lahoz, J; Jiménez-Nacher, I; Poveda, E; Soriano, V; Zahonero, N	1
Ayen, R; Bellido, R; Cardellach, F; Clotet, B; Garrabou, G; Lòpez, S; Miró, O; Morén, C; Negredo, E; Puig, J	1
Borroto-Esoda, K; Feng, JY; Goodman, D; Kutty, N; Ly, JK; Margot, NA; Miller, MD; Myrick, F; Svarovskaia, ES; Wang, R; White, KL	1
Gerondelis, P; Irlbeck, DM; Lanier, E; Parkin, N; Ross, LL; Rouse, E; St Clair, MH; Trinh, L; Underwood, MR	1
Gills Ray, VL; Lee, H; Silkiss, RZ	1
Green, E; Hosseini, SH; Hoying-Brandt, A; Johnson, DM; Kohler, JJ; Lewis, W; Raper, CM; Russ, R; Santoianni, R; Tran, D	1
Alvarez, S; Brumble, LM; Dwyer, JP; Irizarry-Alvarado, JM; Mendez, JC	1
Atta, MG; Fine, DM	1
Yoganathan, K	1
Kirschner, J; Lebrecht, D; Venhoff, AC; Venhoff, N; Walker, UA; Wiech, T	1
Beltrame, A; Bozzano, F; Cenderello, G; Costa, P; De Maria, A; Di Biagio, A; Fenoglio, D; Ferrea, G; Pagano, G	1
Airoldi, M; Cossarizza, A; De Biasi, S; Gibellini, L; Maggiolo, F; Mussini, C; Nasi, M; Pinti, M; Ravasio, V; Roat, E; Suter, F	1
Barnas, D; Bazmi, H; Bixby, C; Jemsek, J; Koontz, D; Mellors, JW	1
Curto, J; Niubo, J; Podzamczer, D; Tiraboschi, JM	1
Bénet, T; Billioud, C; Boibieux, A; Brochier, C; Chevallier, M; Cotte, L; Ferry, T; Miailhes, P; Scoazec, JY; Vanhems, P; Zoulim, F	1
Babusis, D; Durand-Gasselin, L; Flaherty, JF; Hawkins, T; Ray, AS; Reddy, YS; Veikley, W	1
Clauss, M; Desta, Z; Deuter-Reinhard, M; Green, L; Gupta, SK; Kim, C; Taylor, BM	1
Hansen, BE; Janssen, HL; Koëter, T; Komuta, M; Rossing, HH; Schouten, JN; Van der Ende, ME; van der Valk, M; Verheij, J	1
Côté, HC; Hukezalie, KR; Thumati, NR; Wong, JM	1
Govender, T; Mackraj, I; Ojewole, E; Rambharose, S	1

Reviews

7 review(s) available for adenine and didanosine

Article	Year
Targeted therapy of human immunodeficiency virus-related disease. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1991, Volume: 5, Issue:10 Topics: Acquired Immunodeficiency Syndrome; Adenine; Antiviral Agents; CD4 Antigens; Didanosine; Dideoxynucleosides; Dipyridamole; Drug Synergism; Gene Expression Regulation, Viral; Genes, nef; Genes, rev; Genes, tat; HIV; HIV Protease; Interferon Type I; Organophosphonates; RNA-Directed DNA Polymerase; Stavudine; Transcription, Genetic; Zalcitabine; Zidovudine	1991
Effect of tenofovir on didanosine absorption in patients with HIV. The Annals of pharmacotherapy, 2003, Volume: 37, Issue:9 Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Area Under Curve; Clinical Trials as Topic; Didanosine; Drug Interactions; Drug Therapy, Combination; HIV Infections; Humans; Organophosphonates; Organophosphorus Compounds; Tenofovir	2003
Newer treatments for HIV in children. Current opinion in pediatrics, 2004, Volume: 16, Issue:1 Topics: Adenine; Anti-Bacterial Agents; Anti-HIV Agents; Child; Deoxycytidine; Didanosine; Drug Therapy, Combination; Emtricitabine; Enfuvirtide; HIV Envelope Protein gp41; HIV Fusion Inhibitors; HIV Infections; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Peptide Fragments; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir	2004
The continuing evolution of HIV therapy. The AIDS reader, 2003, Volume: 13, Issue:12 Topics: Adenine; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Benzoxazines; Carbamates; CD4 Lymphocyte Count; Cyclopropanes; Delayed-Action Preparations; Deoxycytidine; Didanosine; Dideoxynucleosides; Drug Monitoring; Emtricitabine; Furans; HIV Infections; Humans; Lamivudine; Nevirapine; Oligopeptides; Organophosphates; Organophosphonates; Organophosphorus Compounds; Oxazines; Pyridines; Randomized Controlled Trials as Topic; Stavudine; Sulfonamides; Tenofovir; Treatment Outcome; Viral Load; Zidovudine	2003
Tenofovir and didanosine: a dangerous liaison. The AIDS reader, 2005, Volume: 15, Issue:8 Topics: Adenine; Anti-HIV Agents; Didanosine; Drug Interactions; Drug Therapy, Combination; HIV Infections; Humans; Organophosphonates; Tenofovir	2005
Severe toxicity associated with the combination of tenofovir and didanosine: case report and review. International journal of STD & AIDS, 2005, Volume: 16, Issue:9 Topics: Acidosis, Lactic; Acute Disease; Adenine; Anti-HIV Agents; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Liver Failure; Male; Middle Aged; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir	2005
Tenofovir plus didanosine as Nrti backbone in HIV-infected subjects. Current medicinal chemistry, 2006, Volume: 13, Issue:23 Topics: Adenine; Anti-HIV Agents; Didanosine; Drug Antagonism; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; Humans; Organophosphonates; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Tenofovir	2006

Trials

19 trial(s) available for adenine and didanosine

Article	Year
Once-daily quadruple-drug therapy with adefovir dipivoxil, Lamivudine, Didanosine, and efavirenz in treatment-naive human immunodeficiency virus type 1-infected patients. The Journal of infectious diseases, 2002, Oct-01, Volume: 186, Issue:7 Topics: Adenine; Adult; Alkynes; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Kidney Diseases; Lamivudine; Male; Organophosphonates; Oxazines; Pulse Therapy, Drug; Reverse Transcriptase Inhibitors; RNA, Viral; Time Factors; Treatment Outcome	2002
Tenofovir poses risk with didanosine. AIDS patient care and STDs, 2003, Volume: 17, Issue:6 Topics: Adenine; Anti-HIV Agents; Contraindications; Didanosine; Drug Administration Schedule; Humans; Organophosphonates; Organophosphorus Compounds; Pancreatitis; Tenofovir	2003
Safety and efficacy of once-daily didanosine, tenofovir and nevirapine as a simplification antiretroviral approach. Antiviral therapy, 2004, Volume: 9, Issue:3 Topics: Adenine; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD4-CD8 Ratio; Chemical and Drug Induced Liver Injury; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lipids; Male; Nevirapine; Organophosphonates; Pancreatitis; Patient Compliance; Quality of Life; RNA, Viral; Tenofovir	2004
Early virological failure with a combination of tenofovir, didanosine and efavirenz. Antiviral therapy, 2005, Volume: 10, Issue:1 Topics: Adenine; Adult; Aged; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Didanosine; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Lopinavir; Male; Middle Aged; Mutation; Organophosphonates; Oxazines; Pyrimidinones; RNA, Viral; Tenofovir; Time Factors; Treatment Failure; Viremia	2005
Paradoxical CD4+ T-cell decline in HIV-infected patients with complete virus suppression taking tenofovir and didanosine. AIDS (London, England), 2005, Mar-24, Volume: 19, Issue:6 Topics: Adenine; Adult; Anti-HIV Agents; CD4-Positive T-Lymphocytes; Didanosine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; HIV Infections; Humans; Lymphopenia; Male; Organophosphonates; Retrospective Studies; Tenofovir; Virus Replication	2005
High virological failure rate in HIV patients after switching to a regimen with two nucleoside reverse transcriptase inhibitors plus tenofovir. AIDS (London, England), 2005, Apr-29, Volume: 19, Issue:7 Topics: Acquired Immunodeficiency Syndrome; Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Didanosine; Drug Resistance, Multiple, Viral; Female; Follow-Up Studies; HIV-1; Humans; Male; Middle Aged; Multivariate Analysis; Organophosphonates; Reverse Transcriptase Inhibitors; RNA, Viral; Tenofovir; Treatment Failure; Viral Load; Zidovudine	2005
Measurement of intracellular didanosine and tenofovir phosphorylated metabolites and possible interaction of the two drugs in human immunodeficiency virus-infected patients. Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:5 Topics: Adenine; Anti-HIV Agents; Cell Count; Chromatography, Liquid; Cross-Sectional Studies; Didanosine; Half-Life; HIV Infections; HIV-1; Humans; Kinetics; Longitudinal Studies; Mass Spectrometry; Organophosphonates; Phosphorylation; Reference Standards; Tenofovir	2005
Early virologic failure in HIV-1 infected subjects on didanosine/tenofovir/efavirenz: 12-week results from a randomized trial. AIDS (London, England), 2005, Jul-22, Volume: 19, Issue:11 Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Didanosine; Drug Combinations; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Organophosphonates; Oxazines; Tenofovir; Treatment Failure	2005
Compromised immunologic recovery in treatment-experienced patients with HIV infection receiving both tenofovir disoproxil fumarate and didanosine in the TORO studies. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005, Sep-15, Volume: 41, Issue:6 Topics: Adenine; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Enfuvirtide; HIV Envelope Protein gp41; HIV Infections; Humans; Organophosphonates; Peptide Fragments; Tenofovir; Time Factors; Viral Load	2005
Drug-drug and drug-food interactions between tenofovir disoproxil fumarate and didanosine. Journal of clinical pharmacology, 2005, Volume: 45, Issue:12 Topics: Adenine; Adult; Anti-HIV Agents; Didanosine; Drug Interactions; Drug Therapy, Combination; Female; Food-Drug Interactions; Humans; Male; Organophosphonates; Prodrugs; Reverse Transcriptase Inhibitors; Tenofovir	2005
Simplification therapy with once-daily didanosine, tenofovir and efavirenz in HIV-1-infected adults with viral suppression receiving a more complex antiretroviral regimen: final results of the EFADITE trial. Antiviral therapy, 2005, Volume: 10, Issue:7 Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Didanosine; Dose-Response Relationship, Drug; HIV Infections; HIV-1; Humans; Male; Middle Aged; Odds Ratio; Organophosphonates; Oxazines; Prospective Studies; RNA, Viral; Tenofovir; Treatment Outcome	2005
96-week comparison of once-daily atazanavir/ritonavir and twice-daily lopinavir/ritonavir in patients with multiple virologic failures. AIDS (London, England), 2006, Mar-21, Volume: 20, Issue:5 Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lipids; Lopinavir; Male; Oligopeptides; Organophosphonates; Pyridines; Pyrimidinones; Ritonavir; RNA, Viral; Saquinavir; Tenofovir; Time Factors; Treatment Outcome	2006
Metabolic and anthropometric changes one year after switching from didanosine/stavudine to tenofovir in HIV-infected patients. European journal of medical research, 2007, Feb-26, Volume: 12, Issue:2 Topics: Adenine; Adult; Aged; Anti-HIV Agents; Body Weight; CD4 Lymphocyte Count; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Creatinine; Didanosine; Female; Glomerular Filtration Rate; Glycated Hemoglobin; Hemoglobins; HIV Infections; Humans; Lactic Acid; Male; Middle Aged; Organophosphonates; Phosphates; Skinfold Thickness; Stavudine; Tenofovir; Treatment Outcome; Triglycerides; Uric Acid; Viral Load	2007
Compromised immunologic recovery in patients receiving tipranavir/ritonavir coadministered with tenofovir and didanosine in Randomized Evaluation of Strategic Intervention in multidrug-resiStant patients with tipranavir (RESIST) studies. Journal of acquired immune deficiency syndromes (1999), 2007, Aug-01, Volume: 45, Issue:4 Topics: Adenine; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Organophosphonates; Pyridines; Pyrones; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Sulfonamides; Tenofovir; Treatment Outcome; Viral Load	2007
Low-level K65R mutation in HIV-1 reverse transcriptase of treatment-experienced patients exposed to abacavir or didanosine. Journal of acquired immune deficiency syndromes (1999), 2007, Oct-01, Volume: 46, Issue:2 Topics: Adenine; Alleles; Didanosine; Dideoxynucleosides; Double-Blind Method; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Organophosphonates; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Outcome	2007
Observational study on HIV-infected subjects failing HAART receiving tenofovir plus didanosine as NRTI backbone. Infection, 2007, Volume: 35, Issue:6 Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Didanosine; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Mutation; Organophosphonates; Retrospective Studies; Reverse Transcriptase Inhibitors; Sequence Analysis, DNA; Tenofovir; Treatment Outcome	2007
Changes in metabolic toxicity after switching from stavudine/didanosine to tenofovir/lamivudine--a Staccato trial substudy. The Journal of antimicrobial chemotherapy, 2008, Volume: 61, Issue:6 Topics: Absorptiometry, Photon; Adenine; Adult; Anti-HIV Agents; Body Fat Distribution; Didanosine; DNA, Mitochondrial; HIV Infections; Humans; Lamivudine; Lipids; Liver Function Tests; Organophosphonates; Ritonavir; RNA, Viral; Saquinavir; Stavudine; Tenofovir; Thailand	2008
Mitochondrial changes during D-drug-containing once-daily therapy in HIV-positive treatment-naive patients. Antiviral therapy, 2010, Volume: 15, Issue:1 Topics: Adenine; Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cross-Sectional Studies; Cyclopropanes; Didanosine; Dideoxynucleosides; DNA, Mitochondrial; Drug Administration Schedule; Female; HIV; HIV Infections; Humans; Lamivudine; Male; Mitochondria; Organophosphonates; Reverse Transcriptase Inhibitors; RNA; RNA, Mitochondrial; Tenofovir	2010
Intracellular nucleotide levels during coadministration of tenofovir disoproxil fumarate and didanosine in HIV-1-infected patients. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:4 Topics: Adenine; Adult; Aged; Anti-HIV Agents; Chromatography, Liquid; Deoxyadenine Nucleotides; Deoxyguanine Nucleotides; Didanosine; Dideoxynucleotides; Female; HIV Infections; Humans; Male; Middle Aged; Nucleotides; Organophosphonates; Tandem Mass Spectrometry; Tenofovir; Young Adult	2011

Other Studies

84 other study(ies) available for adenine and didanosine

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Different pattern of activity of inhibitors of the human immunodeficiency virus in lymphocytes and monocyte/macrophages. Antiviral research, 1992, Volume: 17, Issue:4 Topics: Adenine; Antibodies, Viral; Antiviral Agents; Benzodiazepines; CD4 Antigens; Cytokines; Didanosine; Doxorubicin; Drug Interactions; HIV; HIV Infections; Humans; Imidazoles; Leukocytes, Mononuclear; Lymphocytes; Macrophages; Monocytes; Organ Specificity; Organophosphonates; Zalcitabine; Zidovudine	1992
MDL 74,968, a new acyclonucleotide analog: activity against human immunodeficiency virus in vitro and in the hu-PBL-SCID.beige mouse model of infection. Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:5 Topics: Adenine; Animals; Antiviral Agents; Cell Line; Cells, Cultured; Didanosine; DNA, Viral; Guanine; HIV Infections; HIV-1; HIV-2; Humans; Male; Mice; Mice, SCID; Monocytes; Organophosphonates; Spleen; T-Lymphocytes; Zidovudine	1996
Absorption and intestinal metabolism of purine dideoxynucleosides and an adenosine deaminase-activated prodrug of 2',3'-dideoxyinosine in the mesenteric vein cannulated rat ileum. Journal of pharmaceutical sciences, 1998, Volume: 87, Issue:5 Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Anti-HIV Agents; Biological Availability; Biological Transport; Catheterization; Didanosine; Enzyme Inhibitors; Ileum; Intestinal Absorption; Male; Mesenteric Veins; Pentostatin; Permeability; Prodrugs; Purine Nucleosides; Purine-Nucleoside Phosphorylase; Rats; Rats, Sprague-Dawley	1998
Hydroxyurea enhances the activities of didanosine, 9-[2-(phosphonylmethoxy)ethyl]adenine, and 9-[2-(phosphonylmethoxy)propyl]adenine against drug-susceptible and drug-resistant human immunodeficiency virus isolates. Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:8 Topics: Adenine; Anti-HIV Agents; Antineoplastic Agents; Didanosine; DNA, Viral; Drug Resistance, Microbial; HIV Reverse Transcriptase; HIV-1; Humans; Hydroxyurea; Inhibitory Concentration 50; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Tenofovir; Thymidine	1999
Control of SIV rebound through structured treatment interruptions during early infection. Science (New York, N.Y.), 2000, Nov-24, Volume: 290, Issue:5496 Topics: Adenine; Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Didanosine; Drug Administration Schedule; Hydroxyurea; Lymphocyte Activation; Macaca mulatta; Organophosphonates; Organophosphorus Compounds; Random Allocation; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Tenofovir; Viral Load; Viremia; Virus Replication	2000
Update on other antivirals. PI perspective, 1996, Issue:no 18 Topics: Adenine; Antiviral Agents; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Organophosphonates; Stavudine; Zalcitabine; Zidovudine	1996
Tenofovir exhibits low cytotoxicity in various human cell types: comparison with other nucleoside reverse transcriptase inhibitors. Antiviral research, 2002, Volume: 54, Issue:1 Topics: Adenine; Anti-HIV Agents; Antigens, CD34; Cell Line; Didanosine; Dideoxynucleosides; Epithelial Cells; Hematopoietic Stem Cells; Humans; Kidney Tubules, Proximal; Liver; Muscle, Skeletal; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Tumor Cells, Cultured; Zalcitabine; Zidovudine	2002
Dose proportional inhibition of HIV-1 replication by mycophenolic acid and synergistic inhibition in combination with abacavir, didanosine, and tenofovir. Antiviral research, 2002, Volume: 55, Issue:1 Topics: Adenine; Cells, Cultured; Didanosine; Dideoxynucleosides; Dose-Response Relationship, Drug; Drug Resistance; Drug Synergism; Enzyme Inhibitors; HIV-1; Humans; Leukocytes, Mononuclear; Mycophenolic Acid; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Tenofovir; Virus Replication	2002
Anti-HIV agents. Tenofovir and Videx (ddi) EC--some caution required. TreatmentUpdate, 2002, Volume: 14, Issue:6 Topics: Acquired Immunodeficiency Syndrome; Adenine; Anti-HIV Agents; Didanosine; Humans; Organophosphonates; Organophosphorus Compounds; Tenofovir	2002
Phenotypic and genotypic HIV-1 drug resistance assays provide complementary information. Journal of acquired immune deficiency syndromes (1999), 2002, Oct-01, Volume: 31, Issue:2 Topics: Adenine; Anti-HIV Agents; Carbamates; Didanosine; Dideoxynucleosides; Drug Resistance, Viral; Furans; Genotype; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Phenotype; Reverse Transcriptase Inhibitors; Sulfonamides; Tenofovir; Zalcitabine	2002
Fatal lactic acidosis and acute renal failure after addition of tenofovir to an antiretroviral regimen containing didanosine. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2003, Apr-15, Volume: 36, Issue:8 Topics: Acidosis, Lactic; Acute Kidney Injury; Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Didanosine; Drug Synergism; Fatal Outcome; Humans; Male; Middle Aged; Mitochondria; Organophosphonates; Organophosphorus Compounds; Tenofovir	2003
HIV-1 resistance profile of the novel nucleoside reverse transcriptase inhibitor beta-D-2',3'-dideoxy-2',3'-didehydro-5-fluorocytidine (Reverset). Antiviral chemistry & chemotherapy, 2003, Volume: 14, Issue:1 Topics: Adenine; Anti-HIV Agents; Cell Line; Cytidine Triphosphate; Didanosine; Drug Resistance, Multiple, Viral; Genotype; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Species Specificity; Tenofovir; Transfection; Zalcitabine; Zidovudine	2003
Metabolism of tenofovir and didanosine in quiescent or stimulated human peripheral blood mononuclear cells. Pharmacotherapy, 2003, Volume: 23, Issue:6 Topics: Adenine; Anti-HIV Agents; Cells, Cultured; Chromatography, High Pressure Liquid; Culture Media; Didanosine; Drug Interactions; Humans; Leukocytes, Mononuclear; Organophosphonates; Organophosphorus Compounds; Phosphorylation; Tenofovir	2003
Pancreatitis in an HIV-infected person on a tenofovir, didanosine and stavudine containing highly active antiretroviral treatment. The Journal of infection, 2003, Volume: 47, Issue:2 Topics: Adenine; Adult; Antiretroviral Therapy, Highly Active; Didanosine; Drug Interactions; Female; HIV Infections; Humans; Organophosphonates; Organophosphorus Compounds; Pancreatitis; Ritonavir; Stavudine; Tenofovir	2003
Fatal lactic acidosis and mimicking Guillain-Barré syndrome in an adolescent with human immunodeficiency virus infection. The Pediatric infectious disease journal, 2003, Volume: 22, Issue:7 Topics: Acidosis, Lactic; Adenine; Adolescent; Antiretroviral Therapy, Highly Active; Carbamates; Diagnosis, Differential; Didanosine; Disease Progression; Drug Therapy, Combination; Fatal Outcome; Female; Furans; Guillain-Barre Syndrome; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Organophosphonates; Organophosphorus Compounds; Risk Assessment; Severity of Illness Index; Stavudine; Sulfonamides; Tenofovir	2003
Pancreatitis with didanosine and tenofovir disoproxil fumarate [corrected]. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2003, Sep-01, Volume: 37, Issue:5 Topics: Adenine; Adult; Didanosine; Drug Interactions; Fatal Outcome; Female; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Pancreatitis; Tenofovir	2003
Tenofovir-related Fanconi syndrome with nephrogenic diabetes insipidus in a patient with acquired immunodeficiency syndrome: the role of lopinavir-ritonavir-didanosine. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2003, Dec-15, Volume: 37, Issue:12 Topics: Acquired Immunodeficiency Syndrome; Adenine; Adult; Anti-HIV Agents; Diabetes Insipidus, Nephrogenic; Didanosine; Drug Therapy, Combination; Fanconi Syndrome; Humans; Lopinavir; Male; Organophosphonates; Organophosphorus Compounds; Pyrimidinones; Ritonavir; Tenofovir	2003
High rate of virologic failure with once-daily ddI/3TC/TDF. IAPAC monthly, 2003, Volume: 9, Issue:11 Topics: Adenine; Didanosine; HIV Infections; Humans; Lamivudine; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Tenofovir; Viral Load	2003
Role of purine nucleoside phosphorylase in interactions between 2',3'-dideoxyinosine and allopurinol, ganciclovir, or tenofovir. Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:4 Topics: Adenine; Allopurinol; Anti-HIV Agents; Antimetabolites; Antiviral Agents; Biotransformation; Caco-2 Cells; Chromatography, High Pressure Liquid; Didanosine; Drug Interactions; Enzyme Inhibitors; Ganciclovir; Humans; Intestinal Absorption; Kinetics; Organophosphonates; Organophosphorus Compounds; Permeability; Purine-Nucleoside Phosphorylase; Substrate Specificity; Tenofovir	2004
French investigators warn of LPV/TDF/ddI interaction. IAPAC monthly, 2003, Volume: 9, Issue:12 Topics: Adenine; CD4 Lymphocyte Count; Didanosine; HIV Infections; HIV Protease Inhibitors; Humans; Lopinavir; Organophosphonates; Organophosphorus Compounds; Pyrimidinones; Reverse Transcriptase Inhibitors; Tenofovir; Viral Load	2003
Which nucleoside and nucleotide backbone combinations select for the K65R mutation in HIV-1 reverse transcriptase. AIDS (London, England), 2004, Apr-09, Volume: 18, Issue:6 Topics: Adenine; Antiretroviral Therapy, Highly Active; Didanosine; Dideoxynucleosides; Drug Resistance, Multiple, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Nucleosides; Nucleotides; Organophosphonates; Organophosphorus Compounds; Prevalence; Tenofovir	2004
Tenofovir-related nephrotoxicity in HIV-infected patients. AIDS (London, England), 2004, Apr-09, Volume: 18, Issue:6 Topics: Acute Kidney Injury; Adenine; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Didanosine; HIV Infections; HIV-1; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Oxazines; Tenofovir	2004
EU issues warning about HAART regimen. AIDS patient care and STDs, 2004, Volume: 18, Issue:1 Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Didanosine; Dideoxynucleosides; Drug Resistance, Viral; European Union; HIV Infections; Humans; Lamivudine; Organophosphonates; Organophosphorus Compounds; Patient Selection; Pilot Projects; Safety; Tenofovir; Treatment Failure; Viral Load	2004
Unexpected CD4 cell count decline in patients receiving didanosine and tenofovir-based regimens despite undetectable viral load. AIDS (London, England), 2004, Feb-20, Volume: 18, Issue:3 Topics: Adenine; Anti-HIV Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Didanosine; Drug Interactions; Drug Therapy, Combination; Follow-Up Studies; HIV Infections; Humans; Organophosphonates; Organophosphorus Compounds; Retrospective Studies; Reverse Transcriptase Inhibitors; Tenofovir; Viral Load	2004
Didanosine-associated toxicity: a predictable complication of therapy with tenofovir and didanosine? Journal of acquired immune deficiency syndromes (1999), 2004, Apr-01, Volume: 35, Issue:4 Topics: Adenine; Adult; Anti-HIV Agents; Creatinine; Didanosine; Drug Interactions; Drug Therapy, Combination; Female; HIV Infections; Humans; Kidney Diseases; Male; Middle Aged; Organophosphonates; Tenofovir	2004
Phenotypic impact of HIV reverse transcriptase M184I/V mutations in combination with single thymidine analog mutations on nucleoside reverse transcriptase inhibitor resistance. AIDS (London, England), 2004, Aug-20, Volume: 18, Issue:12 Topics: Adenine; Algorithms; Anti-HIV Agents; Databases, Genetic; Didanosine; Dideoxynucleosides; Drug Resistance, Multiple, Viral; HIV; HIV Infections; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Phenotype; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Thymidine; Zalcitabine; Zidovudine	2004
Fatal lactic acidosis associated with coadministration of didanosine and tenofovir disoproxil fumarate. Pharmacotherapy, 2004, Volume: 24, Issue:8 Topics: Acidosis, Lactic; Adenine; Anti-HIV Agents; Area Under Curve; Comorbidity; Didanosine; Drug Interactions; Fatal Outcome; Female; HIV Infections; Humans; Lactates; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Tenofovir	2004
Acute onset of pancreatitis with concomitant use of tenofovir and didanosine. The Annals of pharmacotherapy, 2004, Volume: 38, Issue:10 Topics: Acute Disease; Adenine; Anti-HIV Agents; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Pancreatitis; Tenofovir	2004
Correlation between rules-based interpretation and virtual phenotype interpretation of HIV-1 genotypes for predicting drug resistance in HIV-infected individuals. Journal of virological methods, 2004, Volume: 121, Issue:1 Topics: Adenine; Amino Acid Substitution; Anti-HIV Agents; Didanosine; Dideoxynucleosides; Drug Resistance, Viral; Genotype; HIV Infections; HIV-1; Humans; Microbial Sensitivity Tests; Mutation; Nucleosides; Organophosphonates; Phenotype; Protease Inhibitors; Reverse Transcriptase Inhibitors; Tenofovir	2004
The HIV-1 nucleoside reverse transcriptase inhibitors stavudine and zidovudine alter adipocyte functions in vitro. AIDS (London, England), 2004, Nov-05, Volume: 18, Issue:16 Topics: 3T3-L1 Cells; Adenine; Adipocytes; Animals; Apoptosis; Cell Differentiation; Didanosine; Dideoxynucleosides; HIV-1; HIV-Associated Lipodystrophy Syndrome; Lamivudine; Lipid Metabolism; Mice; Mitochondria; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Zidovudine	2004
Impact of a treatment including tenofovir plus didanosine on the selection of the 65R mutation in highly drug-experienced HIV-infected patients. AIDS (London, England), 2004, Nov-05, Volume: 18, Issue:16 Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Databases, Genetic; Didanosine; DNA, Viral; Drug Resistance, Multiple, Viral; Gene Deletion; Genotype; HIV Infections; HIV-1; Humans; Mutation; Organophosphonates; Tenofovir	2004
Warning on two specific 3-drug regimens: Viread + Didanosine + either Sustiva or Viramune. AIDS treatment news, 2004, Oct-29, Issue:406 Topics: Adenine; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Nevirapine; Organophosphonates; Oxazines; Tenofovir; United States; United States Food and Drug Administration	2004
CD4 cell decline with didanosine and tenofovir and failure of triple nucleoside/nucleotide regimens may be related. AIDS (London, England), 2004, Dec-03, Volume: 18, Issue:18 Topics: Adenine; Anti-HIV Agents; CD4-Positive T-Lymphocytes; Didanosine; Drug Interactions; Drug Therapy, Combination; HIV Infections; Humans; Lymphopenia; Organophosphonates; Purine-Nucleoside Phosphorylase; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Failure	2004
Early virological failure in treatment-naive HIV-infected adults receiving didanosine and tenofovir plus efavirenz or nevirapine. AIDS (London, England), 2005, Jan-28, Volume: 19, Issue:2 Topics: Adenine; Adult; Aged; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Didanosine; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Nevirapine; Organophosphonates; Oxazines; Reverse Transcriptase Inhibitors; RNA, Viral; Tenofovir	2005
Meeting notes from ICAAC. Tenofovir + ddI: a combination to avoid. AIDS clinical care, 2005, Volume: 17, Issue:1 Topics: Adenine; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Viral Load	2005
Selection of a rare resistance profile in an HIV-1-infected patient exhibiting a failure to an antiretroviral regimen including tenofovir DF. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2005, Volume: 32, Issue:3 Topics: Adenine; Adult; Anti-HIV Agents; Didanosine; Dideoxynucleosides; Drug Resistance, Viral; Female; Gabon; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Lopinavir; Microbial Sensitivity Tests; Mutation; Organophosphonates; Pyrimidinones; Tenofovir; Viral Load	2005
In vitro combination studies of tenofovir and other nucleoside analogues with ribavirin against HIV-1. Antiviral therapy, 2005, Volume: 10, Issue:2 Topics: Adenine; Antiviral Agents; Cell Line; Cytopathogenic Effect, Viral; Didanosine; Dideoxynucleosides; Dose-Response Relationship, Drug; Drug Synergism; HIV-1; Humans; Organophosphonates; Reverse Transcriptase Inhibitors; Ribavirin; Tenofovir	2005
The durability of virological success of tenofovir and didanosine dosed at either 400 or 250 mg once daily. HIV medicine, 2005, Volume: 6, Issue:3 Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Didanosine; Drug Administration Schedule; HIV Infections; HIV-1; Humans; Organophosphonates; Retrospective Studies; Survival Rate; Tenofovir; Treatment Failure; Viral Load	2005
Risk factors for CD4 lymphopenia in patients treated with a tenofovir/didanosine high dose-containing highly active antiretroviral therapy regimen. AIDS (London, England), 2005, Jul-01, Volume: 19, Issue:10 Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Didanosine; Female; HIV Infections; Humans; Lymphopenia; Male; Organophosphonates; Risk Factors; Tenofovir	2005
High rate of virological failure in maintenance antiretroviral therapy with didanosine and tenofovir. AIDS (London, England), 2005, Oct-14, Volume: 19, Issue:15 Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Didanosine; Drug Resistance, Multiple, Viral; HIV Infections; HIV-1; Humans; Mutation; Organophosphonates; Tenofovir; Treatment Failure	2005
Dose-dependent influence of didanosine on immune recovery in HIV-infected patients treated with tenofovir. AIDS (London, England), 2005, Nov-18, Volume: 19, Issue:17 Topics: Adenine; Adult; CD4 Lymphocyte Count; Didanosine; Dose-Response Relationship, Immunologic; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Retrospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Tenofovir; Treatment Outcome	2005
Should tenofovir ever be used in association with didanosine? The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases, 2005, Volume: 9, Issue:6 Topics: Adenine; Anti-HIV Agents; Contraindications; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Failure; Viral Load	2005
Longitudinal study on mitochondrial effects of didanosine-tenofovir combination. AIDS research and human retroviruses, 2006, Volume: 22, Issue:1 Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Didanosine; DNA, Mitochondrial; Drug Therapy, Combination; Electron Transport Complex IV; HIV Infections; HIV-1; Humans; Longitudinal Studies; Organophosphonates; Oxidative Phosphorylation; Prospective Studies; Retrospective Studies; Tenofovir	2006
Exploring mitochondrial nephrotoxicity as a potential mechanism of kidney dysfunction among HIV-infected patients on highly active antiretroviral therapy. Antiviral therapy, 2006, Volume: 11, Issue:1 Topics: Adenine; Adult; Aged; Aged, 80 and over; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Biopsy; Didanosine; DNA, Mitochondrial; Drug Therapy, Combination; Female; HIV Infections; Humans; Kidney; Male; Microscopy, Electron; Middle Aged; Mitochondria; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Outcome	2006
Suboptimal CD4 gains in HIV-infected patients receiving didanosine plus tenofovir. The Journal of antimicrobial chemotherapy, 2006, Volume: 57, Issue:5 Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Didanosine; Drug Interactions; HIV Infections; Humans; Mitochondria; Organophosphonates; Purine-Nucleoside Phosphorylase; Tenofovir	2006
Virological response to HIV-1 nucleoside/nucleotide reverse transcriptase inhibitors-based, tenofovir DF-including regimens in the ANRS Aquitaine Cohort. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2006, Volume: 36, Issue:2 Topics: Adenine; Cohort Studies; Didanosine; Dideoxynucleosides; Drug Therapy, Combination; France; HIV Infections; HIV Reverse Transcriptase; HIV-1; Hospitals, University; Humans; Lamivudine; Mutation; Organophosphonates; Retrospective Studies; Reverse Transcriptase Inhibitors; Species Specificity; Tenofovir; Treatment Outcome; Viral Load; Zidovudine	2006
Short-term safety and tolerability of didanosine combined with high- versus low-dose tenofovir disproxil fumarate in ambulatory HIV-1-infected persons. AIDS patient care and STDs, 2006, Volume: 20, Issue:4 Topics: Adenine; Adult; Anti-HIV Agents; Didanosine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Organophosphonates; Retrospective Studies; Tenofovir	2006
Higher risk of hyperglycemia in HIV-infected patients treated with didanosine plus tenofovir. AIDS research and human retroviruses, 2006, Volume: 22, Issue:4 Topics: Adenine; Adult; Anti-HIV Agents; Blood Glucose; Didanosine; Drug Therapy, Combination; Fasting; Female; Follow-Up Studies; HIV Infections; Humans; Hyperglycemia; Linear Models; Male; Organophosphonates; Retrospective Studies; Risk Factors; RNA, Viral; Tenofovir; Time Factors; Treatment Outcome; Virus Replication	2006
The K65R mutation in human immunodeficiency virus type 1 reverse transcriptase exhibits bidirectional phenotypic antagonism with thymidine analog mutations. Journal of virology, 2006, Volume: 80, Issue:10 Topics: Adenine; Amino Acid Substitution; Anti-HIV Agents; Arginine; Didanosine; Dideoxynucleosides; Drug Resistance, Multiple, Viral; Genotype; HIV Reverse Transcriptase; HIV-1; Humans; Lysine; Organophosphonates; Phenotype; Point Mutation; Reverse Transcriptase Inhibitors; Tenofovir; Thymidine; Zalcitabine; Zidovudine	2006
Comment on: suboptimal CD4 gains in HIV-infected patients receiving didanosine plus tenofovir. The Journal of antimicrobial chemotherapy, 2006, Volume: 58, Issue:1 Topics: Adenine; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; HIV Infections; Humans; Organophosphonates; Purine-Nucleoside Phosphorylase; Tenofovir	2006
Virologic and immunologic efficacy of the tenofovir/didanosine/lamivudine regimen. Journal of acquired immune deficiency syndromes (1999), 2006, Volume: 42, Issue:3 Topics: Adenine; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir	2006
Nephrotoxicity in a child with perinatal HIV on tenofovir, didanosine and lopinavir/ritonavir. Pediatric nephrology (Berlin, Germany), 2006, Volume: 21, Issue:7 Topics: Adenine; Anti-HIV Agents; Child; Diabetes Insipidus, Nephrogenic; Didanosine; Drug Therapy, Combination; Fanconi Syndrome; Female; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Kidney; Kidney Diseases; Lopinavir; Organophosphonates; Pregnancy; Pregnancy Complications; Pyrimidinones; Ritonavir; Tenofovir	2006
HIV-1 subtype C viruses rapidly develop K65R resistance to tenofovir in cell culture. AIDS (London, England), 2006, Jun-12, Volume: 20, Issue:9 Topics: Adenine; Didanosine; Drug Administration Schedule; Drug Resistance, Multiple, Viral; Genetic Variation; Genotype; HIV-1; Humans; Inhibitory Concentration 50; Lamivudine; Microbial Sensitivity Tests; Organophosphonates; Polymorphism, Genetic; Reverse Transcriptase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Tenofovir; Time Factors	2006
Hypokalemia in HIV patients on tenofovir. AIDS (London, England), 2006, Aug-01, Volume: 20, Issue:12 Topics: Adenine; Adolescent; Adult; Body Weight; Child; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Hypokalemia; Kidney Diseases; Male; Middle Aged; Organophosphonates; Reverse Transcriptase Inhibitors; Risk Factors; Ritonavir; Tenofovir; Time Factors	2006
In vitro cytotoxicity and mitochondrial toxicity of tenofovir alone and in combination with other antiretrovirals in human renal proximal tubule cells. Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:11 Topics: Adenine; Anti-HIV Agents; Cell Survival; Cells, Cultured; Didanosine; DNA, Mitochondrial; Drug Interactions; Electron Transport Complex IV; Humans; Kidney Tubules, Proximal; Lopinavir; Mitochondria; Organophosphonates; Pyrimidinones; Ritonavir; RNA; Tenofovir; Zidovudine	2006
CD4+ T cell evolution and predictors of its trend before and after tenofovir/didanosine backbone in the presence of sustained undetectable HIV plasma viral load. The Journal of antimicrobial chemotherapy, 2007, Volume: 59, Issue:6 Topics: Adenine; Adult; Aging; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cohort Studies; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Italy; Male; Middle Aged; Organophosphonates; Risk Factors; Sex Characteristics; Tenofovir; Treatment Outcome; Viral Load	2007
Possible allergic cross-reaction to didanosine and tenofovir in an HIV-1-infected woman. AIDS (London, England), 2007, May-11, Volume: 21, Issue:8 Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Didanosine; Drug Hypersensitivity; Drug Interactions; Female; HIV Infections; HIV-1; Humans; Organophosphonates; Tenofovir	2007
Association of serum lipid levels with HIV serostatus, specific antiretroviral agents, and treatment regimens. Journal of acquired immune deficiency syndromes (1999), 2007, May-01, Volume: 45, Issue:1 Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Black People; Cholesterol; Cross-Sectional Studies; Cyclopropanes; Didanosine; Dideoxynucleosides; Drug Therapy, Combination; Fasting; Female; Hispanic or Latino; HIV Infections; HIV Protease Inhibitors; HIV Seronegativity; HIV Seropositivity; HIV-1; Humans; Indinavir; Lamivudine; Lipids; Lipoproteins, HDL; Lipoproteins, LDL; Multivariate Analysis; Nelfinavir; Nevirapine; Organophosphonates; Ritonavir; Stavudine; Tenofovir; Triglycerides; United States; White People	2007
Virologic characterization of HIV type 1 with a codon 70 deletion in reverse transcriptase. Journal of acquired immune deficiency syndromes (1999), 2007, Aug-15, Volume: 45, Issue:5 Topics: Adenine; Antiviral Agents; Cell Line, Transformed; Codon; Deoxycytidine; Didanosine; Dideoxynucleosides; Drug Resistance, Viral; Emtricitabine; HeLa Cells; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Organophosphonates; Point Mutation; Reassortant Viruses; Reverse Transcriptase Inhibitors; Tenofovir	2007
Amprenavir and didanosine are associated with declining kidney function among patients receiving tenofovir. AIDS (London, England), 2007, Jul-11, Volume: 21, Issue:11 Topics: Adenine; Adult; Age Factors; Analysis of Variance; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Body Weight; Carbamates; Creatinine; Didanosine; Drug Interactions; Female; Furans; Glomerular Filtration Rate; HIV Infections; HIV-1; Humans; Kidney; Linear Models; Male; Middle Aged; Organophosphonates; Sulfonamides; Tenofovir; Time Factors	2007
Adverse events experienced by three children taking tenofovir and didanosine in combination. HIV medicine, 2007, Volume: 8, Issue:6 Topics: Adenine; Anti-HIV Agents; Child; Child, Preschool; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Male; Organophosphonates; Tenofovir; Viral Load	2007
Novel drug resistance pattern associated with the mutations K70G and M184V in human immunodeficiency virus type 1 reverse transcriptase. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12 Topics: Adenine; Amino Acid Substitution; Deoxycytidine; Didanosine; Dideoxynucleosides; Drug Resistance, Multiple, Viral; Emtricitabine; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Mutation; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Zidovudine	2007
Semen quality and drug concentrations in seminal plasma of patients using a didanosine or didanosine plus tenofovir containing antiretroviral regimen. Therapeutic drug monitoring, 2007, Volume: 29, Issue:5 Topics: Adenine; Adult; Anti-HIV Agents; Cross-Sectional Studies; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Semen; Sperm Motility; Spermatozoa; Tenofovir	2007
Adaptation of antiretroviral therapy in human immunodeficiency virus infection with central nervous system involvement. Journal of neurovirology, 2008, Volume: 14, Issue:1 Topics: Adenine; Adult; AIDS Dementia Complex; Alkynes; Anti-HIV Agents; Anticonvulsants; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Benzoxazines; Cerebrospinal Fluid; Cyclopropanes; Didanosine; HIV-1; Humans; Indinavir; Lamivudine; Male; Nelfinavir; Nevirapine; Oligopeptides; Organophosphonates; Pyridines; Ritonavir; Seizures; Stavudine; Tenofovir; Viral Load; Virus Replication; Zidovudine	2008
Changing patterns in HIV reverse transcriptase resistance mutations after availability of tenofovir. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008, Jun-01, Volume: 46, Issue:11 Topics: Adenine; Anti-HIV Agents; Didanosine; Drug Resistance, Multiple, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Organophosphonates; Retrospective Studies; Reverse Transcriptase Inhibitors; Tenofovir	2008
Partial immunological and mitochondrial recovery after reducing didanosine doses in patients on didanosine and tenofovir-based regimens. Antiviral therapy, 2008, Volume: 13, Issue:2 Topics: Adenine; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Dose-Response Relationship, Drug; Drug Therapy, Combination; HIV Infections; Humans; Male; Mitochondria; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir	2008
The A62V and S68G mutations in HIV-1 reverse transcriptase partially restore the replication defect associated with the K65R mutation. Journal of acquired immune deficiency syndromes (1999), 2008, Aug-01, Volume: 48, Issue:4 Topics: Adenine; Antiretroviral Therapy, Highly Active; Didanosine; Dideoxynucleosides; Drug Resistance, Multiple, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Organophosphonates; Point Mutation; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Virus Replication	2008
Sensitivity of phenotypic susceptibility analyses for nonthymidine nucleoside analogues conferred by K65R or M184V in mixtures with wild-type HIV-1. The Journal of infectious diseases, 2009, Jan-01, Volume: 199, Issue:1 Topics: Adenine; Anti-HIV Agents; Didanosine; Dideoxynucleosides; Drug Therapy, Combination; Genetic Predisposition to Disease; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Organophosphonates; Phenotype; Plasmids; Tenofovir; Viral Load	2009
Highly active antiretroviral therapy-associated ptosis in patients with human immunodeficiency virus. Archives of ophthalmology (Chicago, Ill. : 1960), 2009, Volume: 127, Issue:3 Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Blepharoptosis; Carbamates; Didanosine; Dideoxynucleosides; Drug Therapy, Combination; Furans; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Male; Middle Aged; Oculomotor Muscles; Organophosphates; Organophosphonates; Sulfonamides; Tenofovir	2009
Tenofovir renal toxicity targets mitochondria of renal proximal tubules. Laboratory investigation; a journal of technical methods and pathology, 2009, Volume: 89, Issue:5 Topics: Adenine; AIDS-Associated Nephropathy; Animals; Anti-HIV Agents; Didanosine; DNA, Mitochondrial; Female; HIV-1; Kidney Tubules, Proximal; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microdissection; Mitochondria; Organophosphonates; Tenofovir; Urothelium	2009
Proximal tubular dysfunction associated with tenofovir and didanosine causing Fanconi syndrome and diabetes insipidus: a report of 3 cases. The AIDS reader, 2009, Volume: 19, Issue:3 Topics: Adenine; Adult; Anti-HIV Agents; Diabetes Insipidus; Didanosine; Drug Therapy, Combination; Fanconi Syndrome; HIV Infections; HIV-1; Humans; Male; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir	2009
Editorial comment: tenofovir nephrotoxicity--the disconnect between clinical trials and real-world practice. The AIDS reader, 2009, Volume: 19, Issue:3 Topics: Adenine; Anti-HIV Agents; Clinical Trials as Topic; Diabetes Insipidus; Didanosine; Drug Therapy, Combination; Fanconi Syndrome; HIV Infections; Humans; Kidney Function Tests; Male; Organophosphonates; Reverse Transcriptase Inhibitors; Risk Factors; Tenofovir	2009
Long-term suppressive therapy for pulmonary aspergilloma in an immunocompromised man with AIDS. Is it always necessary? International journal of STD & AIDS, 2009, Volume: 20, Issue:6 Topics: Adenine; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antifungal Agents; Aspergillosis; Didanosine; Drug Administration Schedule; Drug Interactions; Fatal Outcome; HIV Infections; Humans; Immunocompromised Host; Lung Diseases, Fungal; Male; Middle Aged; Organophosphonates; Pancreatitis; Radiography; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Outcome	2009
Mitochondrial tubulopathy in tenofovir disoproxil fumarate-treated rats. Journal of acquired immune deficiency syndromes (1999), 2009, Jul-01, Volume: 51, Issue:3 Topics: Adenine; Animals; Anti-HIV Agents; Didanosine; DNA, Mitochondrial; Electron Transport; Electron Transport Complex IV; Kidney Tubules, Proximal; Male; Microscopy, Electron, Transmission; Mitochondria; Mitochondrial Diseases; NADH Dehydrogenase; Organophosphonates; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Inhibitors; Tenofovir	2009
Conserved T cell and natural killer cell function in treatment-experienced adults receiving tenofovir plus didanosine as nucleoside reverse transcription inhibitor backbone. Clinical and experimental immunology, 2009, Volume: 158, Issue:1 Topics: Adenine; Adult; CD4 Lymphocyte Count; Cell Proliferation; Didanosine; Drug Therapy, Combination; Flow Cytometry; Fluorescent Antibody Technique; Follow-Up Studies; HIV Infections; HIV-1; Humans; Immunologic Memory; Immunophenotyping; Interferon-gamma; Killer Cells, Natural; Lamivudine; Logistic Models; Male; Middle Aged; Organophosphonates; Reverse Transcriptase Inhibitors; Statistics, Nonparametric; T-Lymphocytes; Tenofovir	2009
Recent FDA approvals and changes. AIDS patient care and STDs, 2010, Volume: 24, Issue:5 Topics: Adenine; Adolescent; Adult; Anti-HIV Agents; Child; Delayed-Action Preparations; Didanosine; Drug Approval; Drug Labeling; HIV Infections; Humans; Organophosphonates; Randomized Controlled Trials as Topic; Tenofovir; United States; United States Food and Drug Administration	2010
Clonal resistance analyses of HIV type-1 after failure of therapy with didanosine, lamivudine and tenofovir. Antiviral therapy, 2010, Volume: 15, Issue:3 Topics: Adenine; Anti-HIV Agents; Didanosine; Drug Resistance, Viral; Drug Therapy, Combination; Genome, Viral; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Organophosphonates; Phenotype; Recombination, Genetic; Reverse Transcriptase Inhibitors; Sequence Analysis, DNA; Tenofovir; Treatment Failure	2010
Maraviroc concentrations in cerebrospinal fluid in HIV-infected patients. Journal of acquired immune deficiency syndromes (1999), 2010, Dec-15, Volume: 55, Issue:5 Topics: Adenine; Adult; Anti-HIV Agents; CCR5 Receptor Antagonists; CD4 Lymphocyte Count; Chromatography, Liquid; Cyclohexanes; Didanosine; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Organophosphonates; Polymerase Chain Reaction; Tandem Mass Spectrometry; Tenofovir; Triazoles; Viral Load	2010
The role of nucleoside and nucleotide analogues in nodular regenerative hyperplasia in HIV-infected patients: a case control study. Journal of hepatology, 2011, Volume: 54, Issue:3 Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Case-Control Studies; Didanosine; Female; HIV Infections; Humans; Hyperplasia; Hypertension, Portal; Liver; Liver Regeneration; Male; Middle Aged; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir	2011
Abacavir, didanosine and tenofovir do not induce inflammatory, apoptotic or oxidative stress genes in coronary endothelial cells. Antiviral therapy, 2011, Volume: 16, Issue:8 Topics: Adenine; Anti-HIV Agents; Apoptosis; Cardiovascular Diseases; Cell Adhesion Molecules; Coronary Vessels; Cytokines; Didanosine; Dideoxynucleosides; Endothelial Cells; Gene Expression; Gene Expression Profiling; HIV Infections; HIV-1; Humans; Inflammation; NADPH Oxidases; Organophosphonates; Oxidative Stress; Primary Cell Culture; Proto-Oncogene Proteins; Tenofovir	2011
Risk factors and outcome of HIV-associated idiopathic noncirrhotic portal hypertension. Alimentary pharmacology & therapeutics, 2012, Volume: 36, Issue:9 Topics: Adenine; Adult; Anti-HIV Agents; Case-Control Studies; Chemical and Drug Induced Liver Injury; Didanosine; Drug Therapy, Combination; Female; HIV Infections; Humans; Hypertension, Portal; Liver; Male; Middle Aged; Multivariate Analysis; Netherlands; Organophosphonates; Risk Factors; Stavudine; Tenofovir; Young Adult	2012
In vitro and ex vivo inhibition of human telomerase by anti-HIV nucleoside reverse transcriptase inhibitors (NRTIs) but not by non-NRTIs. PloS one, 2012, Volume: 7, Issue:11 Topics: Adenine; Alkynes; Anti-HIV Agents; Benzoxazines; Cell Line; Cyclopropanes; Didanosine; Dideoxynucleosides; DNA Primers; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Nevirapine; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Telomerase; Tenofovir; Zidovudine	2012
Comparative buccal permeability enhancement of didanosine and tenofovir by potential multifunctional polymeric excipients and their effects on porcine buccal histology. Pharmaceutical development and technology, 2014, Volume: 19, Issue:1 Topics: Acrylic Resins; Adenine; Administration, Buccal; Alginates; Animals; Anti-HIV Agents; Carboxymethylcellulose Sodium; Didanosine; Excipients; Glucuronic Acid; Hexuronic Acids; Mouth Mucosa; Organophosphonates; Permeability; Polyethylene Glycols; Swine; Tenofovir	2014