Compounds > adenine

adenine and dasatinib

adenine has been researched along with dasatinib in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's8 (66.67)24.3611
2020's3 (25.00)2.80

Authors

AuthorsStudies
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Tallman, M1
Azam, M; Clackson, T; Daley, GQ; Dalgarno, D; Einhorn, W; Huang, WS; Powers, JT; Sawyer, TK; Shakespeare, WC; Zhu, X1
Harbord, N1
Cheng, S; Coleman, M; Guo, A; Lu, P; Ma, J; Wang, YL1
Dagger, SA; Duyvestyn, JM; Forfang, L; Langdon, WY; Myklebust, JH; Oksvold, MP; Smeland, EB; Taylor, SJ1
Göckeritz, E; Guastafierro, A; Hallek, M; Hassenrück, F; Krause, G; Neumann, L; Pizevska, M; Vondey, V1
Levêque, D1
Basso, K; Bosch, F; Dalla-Favera, R; Grandori, C; Inghirami, G; Mittan, SK; Pasqualucci, L; Persaud, M; Rabadan, R; Scuoppo, C; Wang, J1
Beauchamp, E; Berthiaume, LG; Dong, WF; Gamma, JM; Gray, DW; Iyer, A; Lakshmanan, M; Lim, ST; Mackey, JR; Perinpanayagam, MA; Postovit, LM; Raju, A; Read, KD; Tan, SY; Tergaonkar, V; Vincent, KM; Wyatt, PG; Yap, MC1
Amatya, N; Andreotti, A; Engen, JR; Fulton, DB; Joseph, RE; Wales, TE1
Fukuhara, N; Hirasawa, T; Kikuchi, M; Maekawa, M; Mano, N; Ogura, J; Onishi, Y; Onodera, K; Sato, T; Sato, Y; Shigeta, K; Takasaki, S1

Reviews

1 review(s) available for adenine and dasatinib

ArticleYear
Novel nephrotoxins.
    Advances in chronic kidney disease, 2011, Volume: 18, Issue:3

    Topics: Adenine; Alcohols; Angiogenesis Inhibitors; Anticonvulsants; Antipsychotic Agents; Dasatinib; Diphosphonates; Glutamates; Guanine; HIV Protease Inhibitors; Humans; Indoles; Kidney Diseases; Organophosphonates; Oxalates; Pamidronate; Pemetrexed; Phenindione; Plants, Toxic; Proton Pump Inhibitors; Pyrimidines; Pyrroles; Selective Serotonin Reuptake Inhibitors; Sunitinib; Tenofovir; Thiazoles; Triazines

2011

Other Studies

11 other study(ies) available for adenine and dasatinib

ArticleYear
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Existing and emerging therapeutic options for the treatment of acute myeloid leukemia.
    Clinical advances in hematology & oncology : H&O, 2008, Volume: 6, Issue:11

    Topics: Adenine; Adenine Nucleotides; Aminoglycosides; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Arabinonucleosides; Carbazoles; Clofarabine; Cytarabine; Dasatinib; Daunorubicin; fms-Like Tyrosine Kinase 3; Furans; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Naphthalimides; Organophosphonates; Prognosis; Protein Kinase Inhibitors; Pyrimidines; Sesquiterpenes; Staurosporine; Stem Cell Transplantation; Thiazoles; Tretinoin

2008
AP24163 inhibits the gatekeeper mutant of BCR-ABL and suppresses in vitro resistance.
    Chemical biology & drug design, 2010, Volume: 75, Issue:2

    Topics: Adenine; Animals; Benzamides; Binding Sites; Cell Line; Computer Simulation; Dasatinib; Drug Resistance, Neoplasm; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mutation; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Thiazoles

2010
Functional characterization of BTK(C481S) mutation that confers ibrutinib resistance: exploration of alternative kinase inhibitors.
    Leukemia, 2015, Volume: 29, Issue:4

    Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Antineoplastic Agents; B-Lymphocytes; Cell Line, Tumor; Cyclohexylamines; Dasatinib; Drug Resistance, Neoplasm; Female; Gene Expression; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Middle Aged; Mutation; Piperidines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrazoles; Pyrimidines; Pyrroles; RNA, Small Interfering; Signal Transduction; Structure-Activity Relationship; Thiazoles

2015
The targeting of human and mouse B lymphocytes by dasatinib.
    Experimental hematology, 2015, Volume: 43, Issue:5

    Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Antigens, CD19; Apoptosis; B-Lymphocytes; Bone Marrow Cells; Dasatinib; Flow Cytometry; Humans; Male; Mice, Inbred C57BL; Phospholipase C gamma; Piperidines; Precursor Cells, B-Lymphoid; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrazoles; Pyrimidines; Receptors, Antigen, B-Cell; Receptors, Antigen, T-Cell; Signal Transduction; Spleen; Thiazoles; Time Factors

2015
Establishing a chemical genetic link between Bruton tyrosine kinase activity in malignant B cells and cell functions involved in the micro-environmental dialogue.
    British journal of haematology, 2017, Volume: 178, Issue:6

    Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Antineoplastic Agents; B-Lymphocytes; Chemokines; Chemotaxis; Dasatinib; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Humans; Leukemia, B-Cell; Lymphoma, B-Cell; Mutation; Phosphorylation; Piperidines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrazoles; Pyrimidines; Tumor Cells, Cultured

2017
[Dose reassessment: An answer to the high cost of drugs used in oncology?]
    Bulletin du cancer, 2019, Volume: 106, Issue:9

    Topics: Abiraterone Acetate; Adenine; Antineoplastic Agents; Clinical Protocols; Dasatinib; Drug Costs; France; gamma-Glutamyl Hydrolase; Humans; Insurance, Pharmaceutical Services; Medical Oncology; Neoplasms; Nivolumab; Piperidines; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; Recombinant Proteins; United States; Zoledronic Acid

2019
Repurposing dasatinib for diffuse large B cell lymphoma.
    Proceedings of the National Academy of Sciences of the United States of America, 2019, 08-20, Volume: 116, Issue:34

    Topics: Adenine; Animals; Cell Line, Tumor; Dasatinib; Drug Resistance, Neoplasm; Humans; Lymphoma, Large B-Cell, Diffuse; Mechanistic Target of Rapamycin Complex 2; Mice; Phosphatidylinositol 3-Kinases; Piperidines; Proof of Concept Study; PTEN Phosphohydrolase; Pyrazoles; Pyrimidines; Xenograft Model Antitumor Assays

2019
Targeting N-myristoylation for therapy of B-cell lymphomas.
    Nature communications, 2020, 10-22, Volume: 11, Issue:1

    Topics: Acyltransferases; Adenine; Aminopyridines; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dasatinib; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Female; Humans; Lymphoma, B-Cell; Mice; Mice, SCID; Models, Biological; Myristic Acid; Piperidines; Pyrazoles; Pyrimidines; Receptors, Antigen, B-Cell; Signal Transduction; src-Family Kinases; Sulfonamides; Xenograft Model Antitumor Assays

2020
Differential impact of BTK active site inhibitors on the conformational state of full-length BTK.
    eLife, 2020, 11-23, Volume: 9

    Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Catalytic Domain; COVID-19; Dasatinib; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Models, Molecular; Molecular Structure; Mutation; Piperidines; Protein Conformation; Protein Kinase Inhibitors; SARS-CoV-2; src Homology Domains

2020
High-throughput liquid chromatography/electrospray ionization-tandem mass spectrometry method using in-source collision-induced dissociation for simultaneous quantification of imatinib, dasatinib, bosutinib, nilotinib, and ibrutinib in human plasma.
    Biomedical chromatography : BMC, 2021, Volume: 35, Issue:8

    Topics: Adenine; Aniline Compounds; Chromatography, Liquid; Dasatinib; Drug Monitoring; Female; High-Throughput Screening Assays; Humans; Imatinib Mesylate; Leukemia; Male; Middle Aged; Nitriles; Piperidines; Protein Kinase Inhibitors; Pyrimidines; Quinolines; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2021