Compounds > adenine

adenine and dactolisib

adenine has been researched along with dactolisib in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jin, X; Kong, X; Li, H; Xing, Y; Zhang, Z1
Chang, Z; Guo, H; Guo, X; Jia, X; Jin, J; Luo, F; Shi, G; Song, Y1
Ewald, F; Grabinski, N1
Cai, W; Di, W; Ji, Y; Lu, Z; Wu, J; Yang, Q1

Other Studies

4 other study(ies) available for adenine and dactolisib

ArticleYear
Inhibition of autophagy enhances apoptosis induced by the PI3K/AKT/mTor inhibitor NVP-BEZ235 in renal cell carcinoma cells.
    Cell biochemistry and function, 2013, Volume: 31, Issue:5

    Topics: Adenine; Apoptosis; Autophagy; Carcinoma, Renal Cell; Cell Line, Tumor; Chloroquine; Drug Synergism; Drug Therapy, Combination; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Kidney Neoplasms; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinolines; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; TOR Serine-Threonine Kinases

2013
Dual PI3K/mTOR inhibitor NVP-BEZ235-induced apoptosis of hepatocellular carcinoma cell lines is enhanced by inhibitors of autophagy.
    International journal of molecular medicine, 2013, Volume: 31, Issue:6

    Topics: Adenine; Apoptosis; Autophagy; Autophagy-Related Protein 5; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Humans; Imidazoles; Liver Neoplasms; Microtubule-Associated Proteins; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Quinolines; RNA Interference; Signal Transduction; TOR Serine-Threonine Kinases

2013
Ibrutinib (ImbruvicaTM) potently inhibits ErbB receptor phosphorylation and cell viability of ErbB2-positive breast cancer cells.
    Investigational new drugs, 2014, Volume: 32, Issue:6

    Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; ErbB Receptors; Female; Heterocyclic Compounds, 3-Ring; Humans; Imidazoles; Mice; Mitogen-Activated Protein Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Piperidines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; Pyrazoles; Pyrimidines; Quinolines; TOR Serine-Threonine Kinases

2014
Inhibition of Autophagy Increases Proliferation Inhibition and Apoptosis Induced by the PI3K/mTOR Inhibitor NVP-BEZ235 in Breast Cancer Cells.
    Clinical laboratory, 2015, Volume: 61, Issue:8

    Topics: Adenine; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Autophagy-Related Protein 7; Breast Neoplasms; Cell Proliferation; Cell Survival; Chloroquine; Dose-Response Relationship, Drug; Female; Humans; Imidazoles; MCF-7 Cells; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinolines; Ribosomal Protein S6 Kinases, 70-kDa; RNA Interference; Signal Transduction; Time Factors; TOR Serine-Threonine Kinases; Transfection; Ubiquitin-Activating Enzymes

2015