adenine has been researched along with cc 1065 in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (33.33) | 18.7374 |
| 1990's | 6 (50.00) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ding, ZM; Hurley, LH | 1 |
| Hurley, LH; Lin, CH | 1 |
| Brahme, ND; Hatzenbuhler, NT; Jensen, RM; Petzold, G; Scahill, TA; Swenson, DH; Wierenga, W | 1 |
| Hurley, LH; Lee, CS; Needham-VanDevanter, DR | 1 |
| Doisy, R; Hurley, LH; Lee, CS; Needham-VanDevanter, DR; Ross, L; Tang, MS | 1 |
| Hurley, LH; Needham-VanDevanter, DR | 1 |
| Hurley, LH; McGovren, JP; Reynolds, VL | 1 |
| Harshey, RM; Hurley, LH; Sun, D | 1 |
| Blanch, G; Brown, CL; Prakash, AS; Shalders, RL; Young, DJ | 1 |
| Dempcy, RO; Kutyavin, IV; Lukhtanov, EA; Meyer, RB; Mills, AG | 1 |
| Boger, DL; Hedrick, MP; Stauffer, F | 1 |
| Park, HJ | 1 |
1 review(s) available for adenine and cc 1065
| Article | Year |
|---|---|
The chemistry, mechanism of action and biological properties of CC-1065, a potent antitumor antibiotic.
Topics: Adenine; Alkylation; Animals; Base Sequence; Binding Sites; Cell Cycle; Chemical Phenomena; Chemistry; DNA; DNA Repair; Duocarmycins; Humans; In Vitro Techniques; Indoles; Lethal Dose 50; Leucomycins; Mice; Neoplasms, Experimental; Stereoisomerism | 1986 |
11 other study(ies) available for adenine and cc 1065
| Article | Year |
|---|---|
DNA interstrand cross-linking, DNA sequence specificity, and induced conformational changes produced by a dimeric analog of (+)-CC-1065.
Topics: Adenine; Antibiotics, Antineoplastic; Base Sequence; Copper; Cross-Linking Reagents; DNA; DNA Damage; DNA Fingerprinting; Duocarmycins; Electrophoresis; Hydroxides; Hydroxyl Radical; Indoles; Leucomycins; Molecular Sequence Data; Nucleic Acid Conformation; Oligonucleotides; Phenanthrolines; Structure-Activity Relationship; Urea | 1991 |
Determination of the major tautomeric form of the covalently modified adenine in the (+)-CC-1065-DNA adduct by 1H and 15N NMR studies.
Topics: Adenine; Antibiotics, Antineoplastic; Base Sequence; DNA; Duocarmycins; Indoles; Leucomycins; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Nitrogen Isotopes; Nucleic Acid Conformation; Oligodeoxyribonucleotides | 1990 |
An NMR study of the covalent and noncovalent interactions of CC-1065 and DNA.
Topics: Adenine; Antibiotics, Antineoplastic; Base Sequence; Chemical Phenomena; Chemistry; DNA; DNA Adducts; Duocarmycins; Indoles; Leucomycins; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Nucleic Acid Conformation | 1990 |
Demonstration of the asymmetric effect of CC-1065 on local DNA structure using a site-directed adduct in a 117-base-pair fragment from M13mp1.
Topics: Adenine; Deoxyribonuclease I; DNA Restriction Enzymes; Duocarmycins; Indoles; Leucomycins; Nucleic Acid Conformation; Oligonucleotides | 1987 |
Recognition and repair of the CC-1065-(N3-adenine)-DNA adduct by the UVRABC nucleases.
Topics: Adenine; Antibiotics, Antineoplastic; Bacteriophage phi X 174; Base Sequence; DNA; DNA Adducts; DNA Repair; DNA, Viral; Duocarmycins; Endodeoxyribonucleases; Escherichia coli; Escherichia coli Proteins; Genes, Bacterial; Indoles; Leucomycins; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Substrate Specificity; Transfection | 1988 |
Construction and characterization of a site-directed CC-1065-N3-adenine adduct within a 117 base pair DNA restriction fragment.
Topics: Adenine; Antibiotics, Antineoplastic; Base Composition; Base Sequence; DNA; DNA Polymerase I; DNA Restriction Enzymes; Duocarmycins; Indoles; Leucomycins; Nucleic Acid Denaturation | 1986 |
Structural distortions induced by integration host factor (IHF) at the H' site of phage lambda probed by (+)-CC-1065, pluramycin, and KMnO4 and by DNA cyclization studies.
Topics: Adenine; Aminoglycosides; Anti-Bacterial Agents; Bacterial Proteins; Bacteriophage lambda; Base Sequence; Consensus Sequence; DNA; DNA Footprinting; DNA-Binding Proteins; DNA, Circular; Duocarmycins; Hydroxyl Radical; Indoles; Integration Host Factors; Leucomycins; Molecular Probes; Molecular Sequence Data; Nucleic Acid Conformation; Potassium Permanganate | 1996 |
Stability and DNA alkylation rates of the simplest functional analogues of CC-1065, para-hydroxy and para-amino phenethyl bromides.
Topics: Adenine; Alkylation; Antibiotics, Antineoplastic; Base Sequence; Computer Simulation; DNA; Duocarmycins; HeLa Cells; Humans; Hydrocarbons, Brominated; Hydroxybenzoates; Indoles; Leucomycins; Models, Chemical; Molecular Sequence Data; Structure-Activity Relationship | 1999 |
Linkers designed to intercalate the double helix greatly facilitate DNA alkylation by triplex-forming oligonucleotides carrying a cyclopropapyrroloindole reactive moiety.
Topics: Acridines; Adenine; Alkylation; Base Sequence; Binding Sites; Cyclopropanes; DNA; Drug Design; Duocarmycins; Indoles; Intercalating Agents; Leucomycins; Models, Chemical; Nucleic Acid Conformation; Nucleic Acid Hybridization; Oligodeoxyribonucleotides; Substrate Specificity | 1999 |
Substituent effects within the DNA binding subunit of CBI analogues of the duocarmycins and CC-1065.
Topics: Adenine; Alkylation; Antibiotics, Antineoplastic; Binding Sites; DNA; DNA Adducts; Duocarmycins; Humans; Indoles; Inhibitory Concentration 50; Leucomycins; Nucleic Acid Conformation; Pyrroles; Pyrrolidinones; Tumor Cells, Cultured | 2001 |
Evidence for a common molecular basis for sequence recognition of N3-guanine and N3-adenine DNA adducts involving the covalent bonding reaction of (+)-CC-1065.
Topics: Adenine; Antibiotics, Antineoplastic; Base Sequence; Catalysis; DNA; DNA Adducts; Duocarmycins; Guanine; Hydrogen Bonding; Hydrogen-Ion Concentration; Indoles; Leucomycins; Magnetic Resonance Spectroscopy; Models, Molecular; Nucleic Acid Conformation; Oligonucleotides | 2002 |