adenine and carnitine

adenine has been researched along with carnitine in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.00)18.7374
1990's7 (35.00)18.2507
2000's4 (20.00)29.6817
2010's7 (35.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Bertelli, A; Conte, A; Palmieri, L; Ronca, G; Segnini, D; Yu, G1
Christow, CP1
Arduini, A; Calvani, M; Dottori, S; Holme, S; Sciarroni, AF; Sweeney, JD1
Barditch-Crovo, P; Cundy, KC; Ebeling, D; Hendrix, CW; Jaffe, HS; Lietman, PS; Toole, J1
Cherrington, JM; Collier, A; Deeks, SG; Drew, WL; Hellmann, N; Jaffe, HS; Kahn, J; Lalezari, J; Lamy, PD; Li, W; Mulato, AS; Pavia, A; Rodrigue, D; Toole, J1
Highleyman, L1
Carr, A; Chuah, J; Cooper, DA; Doong, N; French, M; Hoy, J; Hudson, J; Law, M; Mallal, S; Smith, D1
Lehotay, DC; LePage, J; Rockman-Greenberg, C; Thompson, JR1
Inoue, M; Kira, Y; Nishikawa, M; Ochi, A; Sato, E1
Arduini, A; Bonomini, M; Brovelli, A; Ciana, A; Dottori, S; Minetti, G; Profumo, A; Seppi, C; Vercellati, C; Zanella, A; Zappa, M1
Chen, CH; Chen, HF; Chen, PH; Chiang, SC; Chien, CL; Chien, YH; Chuang, CY; Ho, HN; Huang, HP; Hwu, WL; Kuo, HC; Li, LT; Stone, L1
Feng, J; Hang, TJ; Jia, YY; Lu, CT; Song, Y; Sun, Y; Wang, S; Wen, AD; Yang, ZF; Zhao, JY1
Chin, DJ; de Niet, A; Jansen, L; Kootstra, NA; Lopatin, U; Plat-Sinnige, MJ; Reesink, HW; Stelma, F; Takkenberg, RB; van Dort, KA; van Iperen, EP; Zwinderman, AH1
Drozd, VIu; Haĭdychuk, VS; Khukhlina, OS; Kosar, LIu; Mandryk, OIe1
Hsieh, C; Rajashekharaiah, V1
Cotticelli, MG; Hauser, LA; Himes, BE; Ho, ES; Lynch, DR; Mesaros, C; Napierala, JS; Napierala, M; Wang, D; Wilson, RB; Xu, P1

Trials

5 trial(s) available for adenine and carnitine

ArticleYear
Anti-human immunodeficiency virus (HIV) activity, safety, and pharmacokinetics of adefovir dipivoxil (9-[2-(bis-pivaloyloxymethyl)-phosphonylmethoxyethyl]adenine) in HIV-infected patients.
    The Journal of infectious diseases, 1997, Volume: 176, Issue:2

    Topics: Adenine; Adult; Anti-HIV Agents; Carnitine; Digestive System; Double-Blind Method; Female; HIV Core Protein p24; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; RNA, Viral

1997
The safety and efficacy of adefovir dipivoxil, a novel anti-human immunodeficiency virus (HIV) therapy, in HIV-infected adults: a randomized, double-blind, placebo-controlled trial.
    The Journal of infectious diseases, 1997, Volume: 176, Issue:6

    Topics: Adenine; Administration, Oral; Adult; Anti-HIV Agents; Carnitine; CD4 Lymphocyte Count; Cytomegalovirus; Cytomegalovirus Infections; DNA, Viral; Double-Blind Method; Female; HIV Infections; HIV-1; Humans; Lymphocyte Count; Male; Middle Aged; Mutation; Organophosphonates; Polymerase Chain Reaction; RNA, Viral; Semen; Sequence Analysis, RNA; T-Lymphocyte Subsets

1997
New drug, new hope.
    TreatmentUpdate, 1998, Volume: 10, Issue:1

    Topics: Adenine; Anti-HIV Agents; Carnitine; CD4 Lymphocyte Count; Clinical Trials as Topic; Dose-Response Relationship, Drug; HIV Infections; Humans; Placebos; Randomized Controlled Trials as Topic; Viral Load

1998
HIV protease inhibitor substitution in patients with lipodystrophy: a randomized, controlled, open-label, multicentre study.
    AIDS (London, England), 2001, Sep-28, Volume: 15, Issue:14

    Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Body Composition; Carnitine; Dideoxynucleosides; Drug Administration Schedule; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Hydroxyurea; Insulin Resistance; Lipodystrophy; Male; Middle Aged; Nevirapine; Organophosphonates; Quality of Life; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome

2001
Impact on L-carnitine Homeostasis of Short-term Treatment with the Pivalate Prodrug Tenofovir Dipivoxil.
    Basic & clinical pharmacology & toxicology, 2013, Volume: 113, Issue:6

    Topics: Adenine; Adult; Antiviral Agents; Carnitine; Dose-Response Relationship, Drug; Female; Hepatitis B; Herpes Simplex; Homeostasis; Humans; Male; Organophosphonates; Prodrugs; Tenofovir

2013

Other Studies

15 other study(ies) available for adenine and carnitine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Effect of propionyl carnitine on energy charge and adenine nucleotide content of cardiac endothelial cells during hypoxia.
    International journal of tissue reactions, 1991, Volume: 13, Issue:1

    Topics: Adenine; Animals; Carnitine; Cells, Cultured; Endothelium, Vascular; Energy Metabolism; Hypoxia; Oxidation-Reduction; Oxygen; Rats; Rats, Inbred Strains; Time Factors; Xanthine Oxidase

1991
[Experiments on the influence of metabolites and antimetabolites on the model of Trichomonas vaginalis. V. Relationship between vitamin-B-complexes and Trichomonas vaginalis].
    Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe A: Medizinische Mikrobiologie und Parasitologie, 1971, Volume: 218, Issue:2

    Topics: Adenine; Adenosine Monophosphate; Bacteriological Techniques; Biotin; Carnitine; Choline; Hydrogen-Ion Concentration; Inositol; Models, Biological; Orotic Acid; Pyridoxine; Riboflavin; Thiamine; Thioctic Acid; Trichomonas vaginalis; Vitamin B Complex; Xanthopterin

1971
Addition of L-carnitine to additive solution-suspended red cells stored at 4 degrees C reduces in vitro hemolysis and improves in vivo viability.
    Transfusion, 1997, Volume: 37, Issue:2

    Topics: Adenine; Blood Preservation; Carnitine; Citrates; Cryopreservation; Erythrocyte Aging; Erythrocytes; Glucose; Hemolysis; Humans; Phosphates; Sodium Chloride

1997
NDA submitted for adefovir.
    AIDS patient care and STDs, 1999, Volume: 13, Issue:9

    Topics: Adenine; Carnitine; Drug Approval; Drug Packaging; Drug Therapy, Combination; HIV Infections; Humans; Organophosphonates; Reverse Transcriptase Inhibitors; United States; United States Food and Drug Administration

1999
Expanded access for adefovir.
    BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation, 1998

    Topics: Adenine; Anti-HIV Agents; Carnitine; Drugs, Investigational; HIV Infections; Humans

1998
Blood acylcarnitine levels in normal newborns and heterozygotes for medium-chain acyl-CoA dehydrogenase deficiency: a relationship between genotype and biochemical phenotype?
    Journal of inherited metabolic disease, 2004, Volume: 27, Issue:1

    Topics: Acyl-CoA Dehydrogenase; Adenine; Carnitine; Diagnosis, Differential; Gene Frequency; Genotype; Guanine; Heterozygote; Humans; Infant, Low Birth Weight; Infant, Newborn; Metabolism, Inborn Errors; Osmolar Concentration; Phenotype

2004
L-carnitine suppresses the onset of neuromuscular degeneration and increases the life span of mice with familial amyotrophic lateral sclerosis.
    Brain research, 2006, Jan-27, Volume: 1070, Issue:1

    Topics: Adenine; Amyotrophic Lateral Sclerosis; Animals; Apoptosis; Carnitine; Disease Progression; Female; Guanine; Hindlimb; Humans; Injections, Subcutaneous; Longevity; Male; Mice; Mice, Transgenic; Muscle Proteins; Muscle, Skeletal; Mutation; Nerve Degeneration; Nerve Tissue Proteins; Oxidation-Reduction; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1; Vitamin B Complex

2006
Cellular properties of human erythrocytes preserved in saline-adenine-glucose-mannitol in the presence of L-carnitine.
    American journal of hematology, 2007, Volume: 82, Issue:1

    Topics: Adenine; Blood Preservation; Carnitine; Cations, Monovalent; Cell Membrane Permeability; Erythrocyte Aging; Erythrocytes; Glucose; Humans; Mannitol; Osmosis; Potassium; Sodium; Sodium Chloride; Time Factors

2007
Human Pompe disease-induced pluripotent stem cells for pathogenesis modeling, drug testing and disease marker identification.
    Human molecular genetics, 2011, Dec-15, Volume: 20, Issue:24

    Topics: Adenine; alpha-Glucosidases; Animals; Base Sequence; Biomarkers; Carnitine; Cell Differentiation; Drug Monitoring; Fibroblasts; Glycogen Storage Disease Type II; Humans; Induced Pluripotent Stem Cells; Mice; Models, Biological; Molecular Sequence Data; Myocytes, Cardiac

2011
HBsAg loss in patients treated with peginterferon alfa-2a and adefovir is associated with SLC16A9 gene variation and lower plasma carnitine levels.
    Journal of hepatology, 2014, Volume: 61, Issue:4

    Topics: Adenine; Adult; Antiviral Agents; Carnitine; CD8-Positive T-Lymphocytes; Drug Therapy, Combination; Female; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Male; Middle Aged; Monocarboxylic Acid Transporters; Organophosphonates; Polyethylene Glycols; Polymorphism, Single Nucleotide; Prognosis; Recombinant Proteins; Treatment Outcome; Vitamin B Complex

2014
[The use of complex tools ezetimibe, hepadyfu fosinopril and correction of blood pressure and endothelial dysfunction in patients with nonalcoholic steatohepatitis and essential hypertension stage II].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 2014, Volume: 67, Issue:2 Pt 2

    Topics: Adenine; Anticholesteremic Agents; Azetidines; Carnitine; Drug Combinations; Endothelium, Vascular; Essential Hypertension; Ezetimibe; Fosinopril; Humans; Hypertension; Non-alcoholic Fatty Liver Disease; Obesity; Vascular Diseases

2014
Influence of L-Carnitine on Stored Rat Blood: A Study on Plasma.
    Turkish journal of haematology : official journal of Turkish Society of Haematology, 2017, Dec-01, Volume: 34, Issue:4

    Topics: Adenine; Animals; Antioxidants; Blood Preservation; Carnitine; Catalase; Citrates; Glucose; Lipid Peroxidation; Male; Oxidative Stress; Phosphates; Plasma; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances

2017
Skin fibroblast metabolomic profiling reveals that lipid dysfunction predicts the severity of Friedreich's ataxia.
    Journal of lipid research, 2022, Volume: 63, Issue:9

    Topics: 3-Hydroxybutyric Acid; Adenine; Carnitine; Ceramides; Coenzyme A; Fibroblasts; Friedreich Ataxia; Guanine; Humans; Iron; Phosphatidylglycerols; Sulfur; Triglycerides

2022