Compounds > adenine

adenine and camptothecin

adenine has been researched along with camptothecin in 19 studies

Research

Studies (19)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (10.53)	18.7374
1990's	4 (21.05)	18.2507
2000's	7 (36.84)	29.6817
2010's	6 (31.58)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Diasio, RB; Stagg, MP	1
McMahon, D; Miller, MJ	1
Abelson, HT; Penman, S; Perlman, S	1
Burris, HA; Eckardt, JR; Fields, S; O'Rourke, T; Rodriguez, GI; Rothenberg, ML; Weiss, GR	1
Courtney, A; Cox, J; Meyer, W; Mues, G; Nemunaitis, J	1
Bjornsti, MA; Pommier, Y; Pourquier, P	1
Innocenti, F; Iyer, L; Ratain, MJ	2
Aimi, N; Saito, K; Sudo, H; Yamazaki, M; Yamazaki, Y	1
Blank, A; Bobola, MS; D Kolstoe, D; Gold, B; Loeb, LA; Meade, EH; Rabinovitch, PS; Silber, JR; Varadarajan, S	1
Bian, JS; Boelsterli, UA; Chan, E; Chan, SY; Duan, W; Ho, PC; Huang, M; Li, X; Tan, TM; Tian, Q; Xiong, W; Yang, H; Zhang, J; Zhou, S; Zhu, YZ	1
Darro, F; Dewelle, J; Dumont, P; El Yazidi, M; Gaussin, JF; Kiss, R; Lefranc, F; Mahieu, T; Mijatovic, T; Ribaucour, F; Sauvage, S; Simon, G; Tuti, J; Van Quaquebeke, E; Van Vynckt, F	1
Corona, G; Innocenti, F; Sandron, S; Sartor, I; Tirelli, U; Toffoli, G; Vaccher, E	1
Li, R; Liu, WT; Song, JR; Sun, K; Wei, LX; Wu, MC; Zhang, JW; Zhang, SS; Zhao, QD; Zong, C	1
Duan, J; Liu, Q; Mu, H; Niu, H; Tang, J; Wang, D	1
Bernstein, KA; Godin, SK; Herken, BW; Lee, AG; Mihalevic, MJ; Resnick, MA; Sobol, RW; Westmoreland, JW; Yu, Z; Zhang, Z	1
Cao, L; Cheng, K; Su, Q; Zhang, X; Zhang, Y	1
Chen, BH; Chen, JY; Chiu, CC; Chiu, YH; Hsu, HW; Hsu, SH; Huang, KC; Huang, WP; Liu, W; Wu, CY	1

Reviews

3 review(s) available for adenine and camptothecin

Article	Year
Novel chemotherapeutic agents in early clinical development. Current opinion in oncology, 1990, Volume: 2, Issue:6 Topics: Adenine; Alkaloids; Anthraquinones; Antineoplastic Agents; Biphenyl Compounds; Camptothecin; Humans; Imides; Irinotecan; Isoquinolines; Naphthalimides; Neoplasms; Organophosphonates; Paclitaxel; Pyrazoles; Quinazolines; Sulfonylurea Compounds; Terpenes; Trimetrexate	1990
New anticancer agents. Cancer chemotherapy and biological response modifiers, 1994, Volume: 15 Topics: Adenine; Animals; Antineoplastic Agents; Camptothecin; Deoxycytidine; Gemcitabine; Humans; Imides; Indoles; Irinotecan; Isoquinolines; Naphthalimides; Organophosphonates; Pyridines; Topotecan; Vinblastine; Vinorelbine	1994
Pharmacogenetics: a tool for individualizing antineoplastic therapy. Clinical pharmacokinetics, 2000, Volume: 39, Issue:5 Topics: Adenine; Antineoplastic Agents; Camptothecin; Dihydrouracil Dehydrogenase (NADP); Fluorouracil; Genotype; Glucuronosyltransferase; Humans; Imides; Irinotecan; Isoquinolines; Mercaptopurine; Methyltransferases; Naphthalimides; Organophosphonates; Oxidoreductases; Pharmacogenetics; Phenotype	2000

Trials

1 trial(s) available for adenine and camptothecin

Article	Year
Novel chemotherapeutic agents in early clinical development. Current opinion in oncology, 1990, Volume: 2, Issue:6 Topics: Adenine; Alkaloids; Anthraquinones; Antineoplastic Agents; Biphenyl Compounds; Camptothecin; Humans; Imides; Irinotecan; Isoquinolines; Naphthalimides; Neoplasms; Organophosphonates; Paclitaxel; Pyrazoles; Quinazolines; Sulfonylurea Compounds; Terpenes; Trimetrexate	1990

Other Studies

16 other study(ies) available for adenine and camptothecin

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Synthesis and maturation of chloroplast and cytoplasmic ribosomal RNA in Chlamydomonas reinhardi. Biochimica et biophysica acta, 1974, Sep-27, Volume: 366, Issue:1 Topics: Adenine; Camptothecin; Chlamydomonas; Chloroplasts; Cytoplasm; Dactinomycin; Electrophoresis, Polyacrylamide Gel; Genes; Isotope Labeling; Molecular Weight; Mutation; Phosphorus Radioisotopes; Rifamycins; RNA, Ribosomal; Species Specificity; Time Factors; Transcription, Genetic; Tritium	1974
Mitochondrial protein synthesis: RNA with the properties of Eukaryotic messenger RNA. Proceedings of the National Academy of Sciences of the United States of America, 1973, Volume: 70, Issue:2 Topics: Adenine; Adenosine; Camptothecin; Carbon Isotopes; Cell Fractionation; Cell Nucleus; Deoxyribonucleases; Electrophoresis, Polyacrylamide Gel; HeLa Cells; Humans; Mitochondria; Polynucleotides; Puromycin; Ribonucleases; RNA; RNA, Messenger; Tritium; Uridine	1973
Irinotecan hydrochloride (CPT-11) resistance identified by K-ras mutation in patients with progressive colon cancer after treatment with 5-fluorouracil (5-FU). American journal of clinical oncology, 1997, Volume: 20, Issue:5 Topics: Adenine; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Camptothecin; Codon; Colonic Neoplasms; Disease Progression; DNA, Neoplasm; Drug Resistance, Neoplasm; Exons; Female; Fluorouracil; Forecasting; Genes, ras; Guanine; Humans; Irinotecan; Male; Middle Aged; Mutation; Prognosis; Retreatment; Sequence Analysis, DNA; Survival Rate; Thymine; Treatment Failure	1997
Induction of topoisomerase I cleavage complexes by the vinyl chloride adduct 1,N6-ethenoadenine. The Journal of biological chemistry, 1998, Oct-16, Volume: 273, Issue:42 Topics: Adenine; Base Pairing; Camptothecin; Carcinogens; DNA Adducts; DNA Topoisomerases, Type I; Humans; Molecular Mimicry; Vinyl Chloride	1998
Pharmacogenetics of anticancer agents: lessons from amonafide and irinotecan. Drug metabolism and disposition: the biological fate of chemicals, 2001, Volume: 29, Issue:4 Pt 2 Topics: Adenine; Antineoplastic Agents; Camptothecin; Humans; Imides; Irinotecan; Isoquinolines; Naphthalimides; Organophosphonates; Pharmacogenetics; Polymorphism, Genetic	2001
Camptothecin biosynthetic genes in hairy roots of Ophiorrhiza pumila: cloning, characterization and differential expression in tissues and by stress compounds. Plant & cell physiology, 2003, Volume: 44, Issue:4 Topics: Acetates; Adenine; Aromatic-L-Amino-Acid Decarboxylases; Base Sequence; Benzyl Compounds; Camptothecin; Carbon-Nitrogen Lyases; Cloning, Molecular; Cyclopentanes; DNA, Complementary; Escherichia coli; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Kinetin; Molecular Sequence Data; NADPH-Ferrihemoprotein Reductase; Naphthaleneacetic Acids; Oxylipins; Phylogeny; Plant Roots; Purines; Rubiaceae; Salicylic Acid; Sequence Analysis, DNA	2003
The Werner syndrome protein confers resistance to the DNA lesions N3-methyladenine and O6-methylguanine: implications for WRN function. DNA repair, 2004, Jun-03, Volume: 3, Issue:6 Topics: 4-Nitroquinoline-1-oxide; Adenine; Alkylating Agents; Antineoplastic Agents; Apoptosis; Camptothecin; Carcinogens; Cells, Cultured; DNA Damage; DNA Helicases; DNA Replication; Drug Resistance; Exodeoxyribonucleases; Fibroblasts; Glioma; Guanine; Humans; Hydroxyurea; Netropsin; O(6)-Methylguanine-DNA Methyltransferase; Oligonucleotides, Antisense; RecQ Helicases; Werner Syndrome; Werner Syndrome Helicase	2004
Human multidrug resistance associated protein 4 confers resistance to camptothecins. Pharmaceutical research, 2005, Volume: 22, Issue:11 Topics: Adenine; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line; Drug Resistance, Neoplasm; Glutathione; Humans; Irinotecan; Methotrexate; Multidrug Resistance-Associated Proteins; Organophosphonates; Paclitaxel	2005
2,2,2-Trichloro-N-({2-[2-(dimethylamino)ethyl]-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin- 5-yl}carbamoyl)acetamide (UNBS3157), a novel nonhematotoxic naphthalimide derivative with potent antitumor activity. Journal of medicinal chemistry, 2007, Aug-23, Volume: 50, Issue:17 Topics: Acetamides; Adenine; Animals; Antineoplastic Agents; Apoptosis; Autophagy; Camptothecin; Cell Line, Tumor; Cellular Senescence; Deoxycytidine; Drug Screening Assays, Antitumor; Erythrocyte Count; Female; Gemcitabine; Humans; Imides; Irinotecan; Isoquinolines; Leukocyte Count; Maximum Tolerated Dose; Mice; Naphthalimides; Neoplasm Transplantation; Organophosphonates; Platelet Count; Structure-Activity Relationship; Topoisomerase I Inhibitors; Urea	2007
Lopinavir-ritonavir dramatically affects the pharmacokinetics of irinotecan in HIV patients with Kaposi's sarcoma. Clinical pharmacology and therapeutics, 2008, Volume: 83, Issue:4 Topics: Adenine; Adult; Aged; Anti-HIV Agents; Antineoplastic Agents, Phytogenic; Antiretroviral Therapy, Highly Active; Area Under Curve; Camptothecin; Drug Therapy, Combination; HIV Infections; Humans; Irinotecan; Lamivudine; Lopinavir; Male; Middle Aged; Organophosphonates; Pyrimidinones; Ritonavir; Sarcoma, Kaposi; Tenofovir; White People	2008
Autophagy inhibition switches low-dose camptothecin-induced premature senescence to apoptosis in human colorectal cancer cells. Biochemical pharmacology, 2014, Aug-01, Volume: 90, Issue:3 Topics: Adenine; AMP-Activated Protein Kinases; Antineoplastic Agents; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Autophagy; Camptothecin; Cell Line, Tumor; Cellular Senescence; Chloroquine; Class III Phosphatidylinositol 3-Kinases; Colorectal Neoplasms; Drug Resistance, Neoplasm; Enzyme Inhibitors; Humans; Lysosomes; Neoplasm Proteins; Osmolar Concentration; Signal Transduction; Tumor Suppressor Protein p53	2014
Autophagy promotes DNA-protein crosslink clearance. Mutation research. Genetic toxicology and environmental mutagenesis, 2016, Volume: 797 Topics: Adenine; Animals; Antineoplastic Agents; Autophagy; Autophagy-Related Protein 5; Autophagy-Related Protein 7; Camptothecin; Cell Line, Tumor; Cell Survival; Chloroquine; DNA Damage; Formaldehyde; Gene Silencing; Humans; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; RNA, Small Interfering; Sirolimus; Ubiquitin-Activating Enzymes; Ultraviolet Rays	2016
The Shu complex promotes error-free tolerance of alkylation-induced base excision repair products. Nucleic acids research, 2016, 09-30, Volume: 44, Issue:17 Topics: Adenine; Alkylation; Camptothecin; Cisplatin; DNA Damage; DNA Polymerase beta; DNA Repair; DNA, Fungal; Epistasis, Genetic; Etoposide; Genes, Fungal; Genetic Loci; Homologous Recombination; Humans; Hydrogen Peroxide; Hydroxyurea; Methyl Methanesulfonate; Models, Biological; Mutation; Mutation Rate; Protein Binding; Radiation, Ionizing; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Ultraviolet Rays	2016
[Inhibition of autophagy initiation stage enhances camptothecin-induced apoptosis in NCI-H1975 cells]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2017, Volume: 33, Issue:12 Topics: Adenine; Apoptosis; Autophagy; Camptothecin; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Chloroquine; Humans; Lung Neoplasms; Transforming Growth Factor beta1	2017
Human non‑small cell lung cancer cells can be sensitized to camptothecin by modulating autophagy. International journal of oncology, 2018, Volume: 53, Issue:5 Topics: Adenine; Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Camptothecin; Carcinoma, Non-Small-Cell Lung; Caspase Inhibitors; Cell Line, Tumor; Cell Movement; DNA Damage; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Histones; Humans; Inhibitory Concentration 50; Lung Neoplasms	2018