adenine has been researched along with alpha-aminopyridine in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (22.73) | 29.6817 |
| 2010's | 12 (54.55) | 24.3611 |
| 2020's | 5 (22.73) | 2.80 |
| Authors | Studies |
|---|---|
| Décout, JL; Dumas, L; Gautier-Luneau, I; Maurel, MC; Routaboul, C; Vergne, J | 1 |
| Leutwyler, S; Müller, A; Talbot, F | 1 |
| Frey, HM; Frey, JA; Leutwyler, S; Müller, A | 1 |
| Barbatti, M; Lischka, H | 1 |
| Baraldi, PG; Kalla, RV; Tabrizi, MA; Zablocki, J | 1 |
| Beukers, MW; Ijzerman, AP; Klaasse, E; Lane, JR; Lin, J; van Bruchem, J | 1 |
| Ai, YJ; Cui, GL; Fang, WH; Luo, Y; Zhang, F | 1 |
| Burger, JA | 1 |
| Wiestner, A | 2 |
| Mukkanti, K; Thappali, SR; Vakkalanka, SK; Varanasi, KV; Veeraraghavan, S | 1 |
| Dharmarajan, S; Dinavahi, SS; Nyayapathy, S; Perumal, Y; Viswanadha, S | 1 |
| Niemann, CU | 1 |
| Baran-Marszak, F; Bernard, S; Cymbalista, F; Danglade, D; Gardano, L; Gribben, J; Laguillier, C; Lazarian, G; Ledoux, D; Marzec, J; Roger, C; Thieblemont, C; Varin-Blank, N | 1 |
| Pettitt, AR; Slupsky, JR; Till, KJ | 1 |
| Casellato, A; Macaccaro, P; Mandato, E; Nunes, SC; Piazza, F; Semenzato, G; Trentin, L; Tubi, LQ; Visentin, A; Zaffino, F | 1 |
| Batchelor, TT; Grommes, C; Nayak, L; Tun, HW | 1 |
| Chiba, J; Hino, A; Inouye, M; Kurosaki, F; Oda, Y | 1 |
| Chen, Z; Li, Y; Tian, C | 1 |
| Fan, L; Kong, YL; Li, JY; Liang, JH; Pan, BH; Wang, L; Wu, JZ; Xia, Y; Xu, W; Zhu, HY | 1 |
| Beauchamp, E; Berthiaume, LG; Dong, WF; Gamma, JM; Gray, DW; Iyer, A; Lakshmanan, M; Lim, ST; Mackey, JR; Perinpanayagam, MA; Postovit, LM; Raju, A; Read, KD; Tan, SY; Tergaonkar, V; Vincent, KM; Wyatt, PG; Yap, MC | 1 |
| Batlevi, CL; De Frank, S; Drullinsky, P; Gerecitano, JF; Hamilton, A; Hamlin, PA; Horwitz, SM; Kumar, A; Matasar, MJ; Michaud, L; Moskowitz, A; Moskowitz, CH; Nakajima, R; Nichols, C; Rademaker, J; Salles, G; Schöder, H; Seshan, V; Stewart, CM; Straus, D; Tsui, DWY; Whiting, K; Younes, A; Zelenetz, AD | 1 |
6 review(s) available for adenine and alpha-aminopyridine
| Article | Year |
|---|---|
Recent developments in A2B adenosine receptor ligands.
Topics: Adenine; Adenosine A2 Receptor Antagonists; Aminopyridines; Animals; Asthma; Drug Discovery; Humans; Pyrazines; Pyrimidines; Receptor, Adenosine A2B; Xanthines | 2009 |
Inhibiting B-cell receptor signaling pathways in chronic lymphocytic leukemia.
Topics: Adenine; Aminopyridines; Antineoplastic Agents; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Morpholines; Oxazines; Phosphoinositide-3 Kinase Inhibitors; Piperidines; Protein Kinase Inhibitors; Purines; Pyrazoles; Pyridines; Pyrimidines; Quinazolinones; Receptors, Antigen, B-Cell; Risk Factors; Signal Transduction | 2012 |
Emerging role of kinase-targeted strategies in chronic lymphocytic leukemia.
Topics: Adenine; Aminopyridines; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Models, Biological; Morpholines; Oxazines; Piperidines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrazoles; Pyridines; Pyrimidines; Receptors, Antigen, B-Cell; Signal Transduction | 2012 |
Emerging role of kinase-targeted strategies in chronic lymphocytic leukemia.
Topics: Adenine; Aminopyridines; Antineoplastic Agents; Clinical Trials as Topic; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocyte Count; Medical Oncology; Morpholines; Mutation; NF-kappa B; Oxazines; Phosphatidylinositol 3-Kinases; Piperidines; Purines; Pyrazoles; Pyridines; Pyrimidines; Quinazolinones; Receptors, Antigen, B-Cell; Signal Transduction; src-Family Kinases | 2012 |
[Targeted treatment of chronic lymphocytic leukaemia].
Topics: Adenine; Aminopyridines; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Morpholines; Oxazines; Piperidines; Purines; Pyrazoles; Pyridines; Pyrimidines; Quinazolinones; Receptors, Antigen, B-Cell; Signal Transduction; Sulfonamides | 2014 |
Introduction of novel agents in the treatment of primary CNS lymphoma.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Aminopyridines; Antineoplastic Agents, Immunological; Burkitt Lymphoma; Central Nervous System Neoplasms; Humans; Immunologic Factors; Lenalidomide; Lymphoma, Large B-Cell, Diffuse; Lymphoma, T-Cell; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Piperidines; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; Rituximab; Salvage Therapy; Thalidomide; Toll-Like Receptors; TOR Serine-Threonine Kinases; Tumor Escape | 2019 |
1 trial(s) available for adenine and alpha-aminopyridine
| Article | Year |
|---|---|
Phase I/Ib Study of the Efficacy and Safety of Buparlisib and Ibrutinib Therapy in MCL, FL, and DLBCL with Serial Cell-Free DNA Monitoring.
Topics: Adenine; Adult; Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Cell-Free Nucleic Acids; Humans; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Morpholines; Phosphatidylinositol 3-Kinases; Piperidines; Pyrazoles; Pyrimidines | 2022 |
15 other study(ies) available for adenine and alpha-aminopyridine
| Article | Year |
|---|---|
New stereoselective reaction of methylglyoxal with 2-aminopyridine and adenine derivatives: formation of imino acid-nucleic base derivatives in water under mild conditions.
Topics: Adenine; Aminopyridines; Imino Acids; Models, Molecular; Nucleic Acids; Pyruvaldehyde; Stereoisomerism; Water | 2002 |
Hydrogen bond vibrations of 2-aminopyridine.2-pyridone, a Watson-Crick analogue of adenine.uracil.
Topics: Adenine; Aminopyridines; Base Pairing; Hydrogen Bonding; Models, Molecular; Pyridones; Spectrometry, Fluorescence; Uracil | 2002 |
Infrared depletion spectra of 2-aminopyridine2-pyridone, a Watson-Crick mimic of adenine.uracil.
Topics: Adenine; Aminopyridines; Chemistry, Physical; Dimerization; Hydrogen; Infrared Rays; Mass Spectrometry; Models, Chemical; Nitrogen; Normal Distribution; Nucleic Acid Conformation; Pyridones; Software; Spectrophotometry, Infrared; Ultraviolet Rays; Uracil | 2004 |
Can the nonadiabatic photodynamics of aminopyrimidine be a model for the ultrafast deactivation of adenine?
Topics: Adenine; Aminopyridines; Carbon; Chemistry, Physical; Electrons; Energy Transfer; Light; Models, Chemical; Molecular Conformation; Nitrogen; Photochemistry; Software; Time Factors; Ultraviolet Rays | 2007 |
Characterization of [3H]LUF5834: A novel non-ribose high-affinity agonist radioligand for the adenosine A1 receptor.
Topics: Adenine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Aminopyridines; Animals; Cell Line; Cell Membrane; Cricetinae; Gene Expression Regulation; Humans; Imidazoles; Radioligand Assay; Receptor, Adenosine A1; Receptor, Adenosine A2B | 2010 |
Ultrafast deactivation processes in the 2-aminopyridine dimer and the adenine-thymine base pair: similarities and differences.
Topics: Adenine; Aminopyridines; Base Pairing; Dimerization; Hydrogen Bonding; Models, Chemical; Models, Molecular; Monte Carlo Method; Photochemistry; Thermodynamics; Thymine | 2010 |
Simultaneous quantitation of IC87114, roflumilast and its active metabolite roflumilast N-oxide in plasma by LC-MS/MS: application for a pharmacokinetic study.
Topics: Adenine; Aminopyridines; Animals; Benzamides; Chromatography, High Pressure Liquid; Cyclopropanes; Drug Stability; Linear Models; Male; Quinazolines; Rats; Rats, Wistar; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry | 2012 |
Combined inhibition of PDE4 and PI3Kδ modulates the inflammatory component involved in the progression of chronic obstructive pulmonary disease.
Topics: Adenine; Aminopyridines; Benzamides; Cell Line, Tumor; Class I Phosphatidylinositol 3-Kinases; Cyclopropanes; Disease Progression; Humans; Lipopolysaccharides; Macrophages; Matrix Metalloproteinase 9; Neutrophils; Nicotiana; Phosphodiesterase 4 Inhibitors; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pulmonary Alveoli; Pulmonary Disease, Chronic Obstructive; Quinazolines; Smoke; U937 Cells | 2014 |
Inhibitors of BCR signalling interrupt the survival signal mediated by the micro-environment in mantle cell lymphoma.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Aged; Aged, 80 and over; Aminopyridines; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Survival; Cells, Cultured; Coculture Techniques; Cytokines; Female; Gene Expression; Humans; Intracellular Signaling Peptides and Proteins; Lymphoma, Mantle-Cell; Male; Middle Aged; Morpholines; Oxazines; Phosphorylation; Piperidines; Protein-Tyrosine Kinases; Pyrazoles; Pyridines; Pyrimidines; Receptors, Antigen, B-Cell; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Syk Kinase; Tumor Cells, Cultured | 2015 |
Expression of functional sphingosine-1 phosphate receptor-1 is reduced by B cell receptor signaling and increased by inhibition of PI3 kinase δ but not SYK or BTK in chronic lymphocytic leukemia cells.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Aminopyridines; Antineoplastic Agents; B-Lymphocytes; Case-Control Studies; Cell Movement; Class I Phosphatidylinositol 3-Kinases; Gene Expression Regulation, Leukemic; Germinal Center; Human Umbilical Vein Endothelial Cells; Humans; Integrins; Intracellular Signaling Peptides and Proteins; Leukemia, Lymphocytic, Chronic, B-Cell; Lymph Nodes; Lysophospholipids; Morpholines; Oxazines; Piperidines; Primary Cell Culture; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Purines; Pyrazoles; Pyridines; Pyrimidines; Quinazolinones; Receptors, Antigen, B-Cell; Receptors, Lysosphingolipid; Signal Transduction; Sphingosine; Sphingosine-1-Phosphate Receptors; Syk Kinase | 2015 |
CX-4945, a Selective Inhibitor of Casein Kinase 2, Synergizes with B Cell Receptor Signaling Inhibitors in Inducing Diffuse Large B Cell Lymphoma Cell Death.
Topics: Adenine; Aminopyridines; Apoptosis; Casein Kinase II; Cell Proliferation; Drug Synergism; Humans; Lymphoma, Large B-Cell, Diffuse; Morpholines; Naphthyridines; Oxazines; Phenazines; Piperidines; Pyrazoles; Pyridines; Pyrimidines; Receptors, Antigen, B-Cell; Tumor Cells, Cultured | 2018 |
2-Aminopyridine as a Nucleobase Substitute for Adenine in DNA-like Architectures: Synthesis of Alkynyl
Topics: Adenine; Aminopyridines; DNA; Nucleotides; Thymine | 2020 |
Chidamide combined with ibrutinib improved the prognosis of primary bone marrow diffuse large B cell lymphoma.
Topics: Adenine; Aged; Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Bone Marrow; Bone Marrow Cells; China; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Lymphoma, Large B-Cell, Diffuse; Male; Piperidines; Prednisone; Prognosis; Rituximab; Transplantation, Autologous; Vincristine | 2020 |
Chidamide, a histone deacetylase inhibitor, inhibits autophagy and exhibits therapeutic implication in chronic lymphocytic leukemia.
Topics: Adenine; Adult; Aged; Aged, 80 and over; Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Autophagy-Related Proteins; Benzamides; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Phosphatidylinositol 3-Kinase; Piperidines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Signal Transduction; TOR Serine-Threonine Kinases | 2020 |
Targeting N-myristoylation for therapy of B-cell lymphomas.
Topics: Acyltransferases; Adenine; Aminopyridines; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dasatinib; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Female; Humans; Lymphoma, B-Cell; Mice; Mice, SCID; Models, Biological; Myristic Acid; Piperidines; Pyrazoles; Pyrimidines; Receptors, Antigen, B-Cell; Signal Transduction; src-Family Kinases; Sulfonamides; Xenograft Model Antitumor Assays | 2020 |