adenine has been researched along with alanosine in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Graff, JC; Plagemann, PG | 1 |
| Dye, FJ; Kollar, EJ | 1 |
| Bingham, H; Chan, VL; Du, RP; Juranka, P; Pang, JC | 1 |
| Allan, PW; Bennett, LL; Brockman, RW; Rose, LM; Shaddix, SC | 1 |
| Martin, GM; Turker, MS | 1 |
| Assandri, A; Barone, D; Galliani, G; Grandi, M; Lancini, GC; Mistrello, G | 1 |
| El Sayed, YM; Nguyen, BT; Sadée, W | 1 |
| Cadman, E; Goldberg, D; Heimer, R | 1 |
| Gupta, RS | 1 |
| Batova, A; Carrera, CJ; Cottam, H; Diccianni, MB; Yu, AL; Yu, J | 1 |
| Burris, HA; Kindler, HL; Oliff, IA; Sandler, AB | 1 |
1 trial(s) available for adenine and alanosine
| Article | Year |
|---|---|
A phase II multicenter study of L-alanosine, a potent inhibitor of adenine biosynthesis, in patients with MTAP-deficient cancer.
Topics: Adenine; Adolescent; Adult; Aged; Alanine; Antimetabolites, Antineoplastic; Drug Administration Schedule; Female; Humans; Male; Neoplasms; Purine-Nucleoside Phosphorylase | 2009 |
11 other study(ies) available for adenine and alanosine
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Alanosine toxicity in Novikoff rat hepatoma cells due to inhibition of the conversion of inosine monophosphate to adenosine monophosphate.
Topics: Adenine; Adenosine Monophosphate; Adenosine Triphosphate; Alanine; Aspartic Acid; Carcinoma, Hepatocellular; Cell Division; Cell Line; Cells, Cultured; Depression, Chemical; DNA, Neoplasm; Glucose; Hypoxanthines; Inosine Nucleotides; Liver Neoplasms; Mengovirus; Neoplasm Proteins; Neoplasms, Experimental; Nitroso Compounds; Purine Nucleotides; Pyrimidine Nucleotides; RNA, Neoplasm; Succinates; Uracil Nucleotides; Uridine | 1976 |
Inhibition of mouse molar tooth germ morphogenesis in organ culture by alanosine.
Topics: Adenine; Alanine; Animals; Mice; Mice, Inbred BALB C; Mitosis; Molar; Morphogenesis; Nitrosamines; Odontogenesis; Organ Culture Techniques; Tooth Germ | 1978 |
Imbalance of purine nucleotides in alanosine-resistant baby hamster kidney cells.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Kinase; Adenylosuccinate Lyase; Adenylosuccinate Synthase; Alanine; Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Cricetinae; Culture Media; Humans; Hypoxanthine Phosphoribosyltransferase; Mutation; Phosphotransferases; Purines; Selection, Genetic; Transformation, Genetic; Uridine | 1989 |
Alterations in nucleotide pools induced by 3-deazaadenosine and related compounds. Role of adenylate deaminase.
Topics: Adenine; Adenosine Kinase; Alanine; Aminoglycosides; AMP Deaminase; Animals; Anti-Bacterial Agents; Cell Survival; Coformycin; Hypoxanthine; Hypoxanthines; Mice; Nucleotide Deaminases; Nucleotides; Time Factors; Tubercidin | 1988 |
Induction of adenine salvage in mouse cell lines deficient in adenine phosphoribosyltransferase.
Topics: 2-Aminopurine; Adenine; Adenine Phosphoribosyltransferase; Alanine; Animals; Azaserine; Cell Line; Cross Reactions; Drug Resistance; Gene Expression Regulation; Karyotyping; Mice; Mycoplasma; Pentosyltransferases | 1985 |
Contragestational profile of the tumor-inhibiting agent, L-alanosine, in the rat and the hamster.
Topics: Adenine; Alanine; Animals; Antibiotics, Antineoplastic; Aspartic Acid; Cell Division; Cricetinae; Dose-Response Relationship, Drug; Female; Fertility; Mesocricetus; Pregnancy; Rats; Rats, Inbred Strains; Time Factors | 1985 |
Interaction among the distinct effects of adenine and guanine depletion in mouse lymphoma cells.
Topics: Adenine; Adenosine; Alanine; Animals; Antimetabolites, Antineoplastic; Cell Division; DNA Replication; Guanine; Kinetics; Lymphoma; Methylthioinosine; Mice; Mycophenolic Acid | 1984 |
Modulation of fluoropyrimidine metabolism in L1210 cells by L-alanosine.
Topics: Adenine; Alanine; Animals; Aspartic Acid; Cells, Cultured; Clone Cells; Deoxyuridine; Leukemia L1210; Mice; Nucleotides; Pyrimidines; Time Factors | 1983 |
A novel synergistic effect of alanosine and guanine on adenine nucleotide synthesis in mammalian cells. Alanosine as a useful probe for investigating purine nucleotide metabolism.
Topics: Adenine; Adenine Nucleotides; Adenylosuccinate Synthase; Alanine; Animals; Cell Division; Cell Line; Cricetinae; Dose-Response Relationship, Drug; Drug Synergism; Female; Guanine; Humans; Nitrosamines; Ovary; Purine Nucleotides | 1980 |
EFA (9-beta-D-erythrofuranosyladenine) is an effective salvage agent for methylthioadenosine phosphorylase-selective therapy of T-cell acute lymphoblastic leukemia with L-alanosine.
Topics: Adenine; Alanine; Antibiotics, Antineoplastic; Cell Line, Tumor; Deoxyadenosines; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme Inhibitors; Erythroid Precursor Cells; Furans; Granulocyte Precursor Cells; Humans; Leukemia-Lymphoma, Adult T-Cell; Purine-Nucleoside Phosphorylase; Salvage Therapy; Thionucleosides | 2006 |