adenine has been researched along with adenosine in 1055 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 589 (55.83) | 18.7374 |
| 1990's | 196 (18.58) | 18.2507 |
| 2000's | 143 (13.55) | 29.6817 |
| 2010's | 88 (8.34) | 24.3611 |
| 2020's | 39 (3.70) | 2.80 |
| Authors | Studies |
|---|---|
| Bhave, DP; Carroll, KS; Hong, JA | 1 |
| Bearne, SL; Lunn, FA; Roy, AC | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Bing, T; Chang, T; Liu, X; Qi, C; Shangguan, D; Zhang, N | 1 |
| Carlson, EE; Goswami, M; Wilke, KE | 1 |
| Di Prisco, G | 1 |
| McCann, PA; Pogell, BM; Redshaw, PA; Sankaran, L | 1 |
| Divekar, AY | 1 |
| Farmer, JB; Farrar, DG | 1 |
| Corbin, JD; Sugden, PH | 1 |
| Kohno, S; Matsuno, T; Shirasawa, N | 1 |
| Wong, JL; Zady, MF | 1 |
| Meuwissen, HJ; Pollara, B; Schrader, WP | 1 |
| Ivanova, GS; Kagan, ZS; Krupianko, VI | 1 |
| Saebø, J; Ueland, PM | 1 |
| Bloch, A | 1 |
| Dozi-Vassiliades, J; Kokolis, N; Tsiamitas, C | 1 |
| Langer, J; Szyfter, K | 1 |
| Königk, E; Rasoul, SA | 1 |
| Ipata, PL; Mura, U; Romano, M; Sgarrella, F | 1 |
| Magill, CW; Magill, JM | 2 |
| Kutas, J; Mozsik, G; Vizi, F | 1 |
| Colman, RF; Mansour, TE | 1 |
| McBurney, MW; Whimore, GF | 1 |
| Daly, JW; Skolnick, P | 1 |
| Kostopoulos, GK; Limacher, JJ; Phillis, JW | 2 |
| Greenspan, J; Love, JD; Orengo, A | 1 |
| Clark, RB; Cubeddu, L; Johnson, GL; Ortmann, R; Perkins, JP; Su, YF | 1 |
| Berlin, RD; Yin, HH | 1 |
| Belamarich, FA; Shepro, D; Stiller, RA | 1 |
| Caplan, AI; Rosenberg, MJ | 1 |
| Weiner, M | 1 |
| Daly, JW; Mah, HD | 1 |
| Isaksson, O; Rosberg, S; Selstam, G | 1 |
| Hayano, K; Ishida, N; Mizuno, K; Sakaguchi, K; Tsujino, M | 1 |
| Berlin, RD; Oliver, JM | 2 |
| Borg, DC; Schmidt, J | 1 |
| Huot, J; Jard, S; Penit, J | 1 |
| Hillyard, D; Olivera, BM; Rechsteiner, M | 1 |
| Fredholm, BB | 1 |
| Londesborough, J | 1 |
| Kapoor, HC; Sachar, RC | 1 |
| Daly, JW; Dismukes, RK | 1 |
| Tamura, Z; Yoshioka, M | 1 |
| McIlwain, H | 2 |
| Albach, RA; Booden, T; Boonlayangoor, P | 1 |
| Rapaport, E; Zamecnik, PC | 1 |
| Cohen, A; Martin, DW; Ullman, B | 1 |
| Livshits, VA | 1 |
| Ozato, K | 1 |
| Seegmiller, JE; Shreier, MH; Waldmann, TA; Watanabe, T | 1 |
| Hershfield, MS; Seegmiller, JE; Snyder, FF | 3 |
| Bally, PR; Bogdanov, SS; Honegger, UE | 1 |
| Brown, RD; Kronenberg, H; Rickard, KA; Yuen, E | 1 |
| Allison, AC; Hovi, T; Raivio, K; Vaheri, A | 1 |
| Ueland, PM | 1 |
| Albach, RA; Booden, T; Boonlayangoor, P; Stern, ML | 1 |
| Cohen, SS; North, TW | 1 |
| Fredholm, BB; Hjemdahl, P | 1 |
| Saebø, J; Ueland, M | 1 |
| Fredholm, BB; Vernet, L | 1 |
| Bartlett, V; Nakatsu, K; Stewart, RR | 1 |
| Del Giudice, R; Hatanaka, M; Long, C | 1 |
| Budowsky, EI; Ivanchenko, VA; Simukova, NA; Titschenko, AI; Wulfson, NS | 1 |
| Cohen, A; Hirschhorn, R; Hong, R; Horowitz, SD; Martin, DW; Polmar, SH; Rubinstein, A | 1 |
| Cohen, SS; Lapi, L | 1 |
| Dryden, EE; Manery, JF; Riordan, JR; Woo, YT | 1 |
| Cohen, A; Gudas, LJ; Martin, DW; Ullman, B | 1 |
| Hovi, T; Raivio, KO | 2 |
| Goldblum, RM; Goldman, AS; May, LT; Mills, GC; Nelson, JA; Schmalstieg, FC | 1 |
| Spinowitz, BS; Zadunaisky, JA | 1 |
| Ko, RC; Wong, PC | 1 |
| Geiger, JR; Speyer, JF | 1 |
| Beacham, IR; Nissim, A; Price, G; Yagil, E | 1 |
| Akkerman, JW; De Bree, PK; De Bruyn, CH; Siegenbeek Van Heukelom, LH; Staal, GE; Stoop, JW; Wadman, SK; Zegers, BJ | 1 |
| Magnuson, NS; Perryman, LE | 1 |
| Johnston, JM; Kredich, NM | 1 |
| Bleck, V; Lewin, E | 1 |
| Barankiewicz, J; Jezewska, MM; Kadłubowska, H | 1 |
| Deeprose, RD; Duncan, GS; Harvey, RJ; Wolberg, G; Zimmerman, TP | 1 |
| Chiba, P; Kraupp, M; Müller, MM | 1 |
| Iwahashi, H; Kainosho, M; Kyogoku, Y; Sugeta, H; Watanabe, M | 1 |
| Dowdall, MJ; Lane, DA; Zimmermann, H | 1 |
| Parish, RW | 1 |
| Dye, FJ; Kollar, EJ | 1 |
| Polasa, H; Rao, SP | 1 |
| MacFarlane, DE; Mills, DC | 1 |
| Goh, SH; LéJohn, HB; Wright, JA | 1 |
| Chheda, GB; Cox, C; Dutta, SP; Hong, CI; Parthasarthy, R; Tritsch, GL | 1 |
| Cox, RP; Holland, MJ; Klein, NC | 1 |
| Carleton, JS; Gordon, JL; Hutchings, A; Pearson, JD | 1 |
| Bowman, K; Gangarosa, LP; Green, K; Hill, JM; Hull, DS; Park, NH; Tuggle, CL | 1 |
| Hayashi, E; Kunitomo, M; Mori, M; Shinozuka, K; Yamada, S | 1 |
| Dean, BM; Perrett, D; Sahota, A; Simmonds, HA; Van Acker, KJ | 1 |
| Taylor, MW; Witney, FR | 1 |
| Andreeva, IS; Poslovina, AS; Salganik, RI; Vasiunina, EA | 3 |
| Love, SH; Rubin, HE | 1 |
| Anderson, JM; Roth, R | 1 |
| MacLennan, BD | 1 |
| Erbe, J; Howard, R; Marz, R; Plagemann, PG; Sheppard, JR; Zylka, JM | 1 |
| Drummond, AH; Gordon, JL; Grainge, CA; MacIntyre, DE | 1 |
| Polmar, SH; Raivio, KO; Schwartz, AL; Stern, RC | 1 |
| Raivio, KO; Rovamo, L; Smith, C | 1 |
| Eberl, R; Partsch, G | 1 |
| Ma, WC | 1 |
| Takegami, T; Yoshida, K | 1 |
| Dean, B; Perrett, D | 1 |
| Hirschhorn, R; Sela, E | 1 |
| Buttin, G; Debatisse, M | 1 |
| Kekomäki, MP; Raivio, KO; Rovamo, LM; Smith, CM | 1 |
| Kolassa, N; Stengg, R; Turnheim, K | 2 |
| Aussedat, J; Rossi, A | 1 |
| Dean, BM; Perrett, D | 1 |
| Blanco, FG; Buc, H; Morange, M; Vandenbunder, B | 1 |
| Holmsen, H; Lips, JP; Sixma, JJ; Trieschnigg, AM | 1 |
| Battell, ML; Henderson, JF | 1 |
| de Bono, DP; Gordon, JL; MacIntyre, DE; Pearson, JD | 1 |
| Dawes, EA; Reece, P; Toth, D | 1 |
| Nose, K | 1 |
| Makarov, AD; Mal'ian, AN; Sarancha, IuP | 1 |
| Lewin, E | 1 |
| Firtel, RA; Pederson, T | 1 |
| Darnell, JE; Puckett, L; Sheiness, D | 1 |
| Abelson, HT; Green, H; Johnson, LF; Penman, S; Williams, JG | 1 |
| MacInnis, AJ; Page, CR | 1 |
| Cohen, SS; Plunkett, W | 1 |
| Babior, BM; Hull, WE; Mauck, L | 1 |
| Beacham, IR; Yagil, E | 1 |
| Greenberg, JR | 1 |
| Van Dyke, K | 1 |
| Brownlee, BG; Hall, RH; Whitty, CD | 1 |
| Lucacchini, A; Montali, U; Ronca, G; Rossi, CA | 1 |
| Geel, SE; Gonzales, LW | 1 |
| Miech, FP; Senft, AW; Senft, DG | 1 |
| Cornford, EM; Oldendorf, WH | 1 |
| Brawerman, G; Jeffery, WR | 2 |
| Léjohn, HB | 1 |
| Lazorik, FC; Schramm, VL | 1 |
| Friderici, K; Kelley, DE; Perry, RP; Rottman, F | 1 |
| Blume, AJ; Foster, CJ | 1 |
| Mel'gunov, VI | 1 |
| Clements, GB; Subak-Sharpe, JH | 2 |
| Guranowski, A; Schneider, Z | 1 |
| Cane, D; Fox, IH; Gladman, DD; Keystone, EC; Moore, M | 1 |
| Eguchi, Y; Ochi, D; Yashima, S | 1 |
| Lohmann, W; Sapper, H; Schimmack, W | 1 |
| Lohmann, W; Schimmack, W | 1 |
| Moffatt, JG; Prisbe, EJ; Smejkal, J; Verheyden, JP | 1 |
| Henderson, JF; Smith, CM | 1 |
| Rahn, RO | 1 |
| Buhl, MR | 1 |
| Behrman, EJ; Ragazzo, JA | 1 |
| Hurt, CM; Pelleg, A | 1 |
| Haley, B; Lin, PC; Shoemaker, M | 1 |
| Firth, JL; Kendall, DA; Millns, PJ | 1 |
| Robin, L; Srivastava, US; Thakur, ML | 1 |
| Close, DM; Hole, EO; Nelson, WH; Sagstuen, E | 1 |
| De Croos, PZ; Johnson, ME; Kar, L; Matsumura, P; Roman, SJ | 1 |
| Mita, M | 1 |
| Kang, HK; Shim, SC; Shin, EJ | 1 |
| Berne, RM; Coleman, SD; Ely, SW; Matherne, GP | 1 |
| Belt, JA; Cass, CE; Dagnino, L; Gati, WP; Paterson, AR; Vijayalakshmi, D | 1 |
| Martin, PL | 1 |
| Davey, RA; Duffield, GA; Ey, PL | 1 |
| Barrett, RJ; Droppleman, DA; Wright, KF | 1 |
| O'Regan, MH; Perkins, LM; Phillis, JW | 1 |
| Tsiftsoglou, AS; Vizirianakis, IS; Wong, W | 1 |
| Belardinelli, L; Shryock, JC; Travagli, HC | 1 |
| Cornford, EM; Fitzpatrick, AM | 1 |
| Geiger, JD; Gu, JG | 1 |
| Hasan, A; Srivastava, PC | 1 |
| Deeley, MC | 1 |
| Fujise, H; Higashijima, M; Hisamatsu, S; Ogawa, E; Sakamoto, Y; Sonoki, S; Takahashi, R | 1 |
| Barsacchi, D; Camici, M; Cappiello, M; Del Corso, A; Ipata, PL; Mura, U; Tozzi, MG | 1 |
| Ayers, CR; Feldman, MD; Iflah, S; Linden, J; Patel, A; Ripley, ML; Taylor, HE; Woodward, EB | 1 |
| Cunha, RA; Sebastião, AM | 1 |
| Cerný, J; Holý, A; Hrebabecký, H; Merta, A; Otmar, M; Rosenberg, I; Sedivá, K; Veselý, J; Vlach, J; Votruba, I | 1 |
| Inoue, H; Ishida, H; Kasahara, S; Nagata, T; Nishikawa, S; Ohishi, K; Wakano, Y; Yamauchi, N | 1 |
| Boyd, FL; Porter, DJ | 1 |
| Camiña, F; Castro-Gago, M; Lojo, S; Rodríguez-Núñez, A; Rodríguez-Segade, S | 1 |
| Duley, JA; Montero, C; Simmonds, HA; Smolenski, RT | 1 |
| Capuozzo, E; Crifò, C; Salerno, C; Siems, W | 1 |
| Lieberman, M; Wagenknecht, B | 1 |
| Burrier, AC; Jeng, AY; Oei, HH | 1 |
| Paglia, DE; Valentine, WN | 1 |
| Arai, S; Kaneko, C; Katagiri, N; Kurimoto, A; Nomura, M; Sato, H; Tameda, C; Toyota, A | 1 |
| Hanai, Y; Maruyama, T; Sato, Y | 1 |
| Baba, M; De Clercq, E; Konno, K; Shigeta, S; Yokota, T | 1 |
| Dorheim, TA; Hoffman, A; Mentzer, RM; Van Wylen, DG | 1 |
| Glaesser, D; Iwig, M | 1 |
| Carney, DF; Papadimitriou, JC; Shin, ML | 1 |
| Akaoka, I; Fujimori, S; Kamatani, N; Kaneko, K; Kumakawa, T | 1 |
| Güemes, M; Ibañez, C; Marin, J; Rivilla, F; Salaices, M; Sanchez-Ferrer, CF | 1 |
| Domenighini, M; Montecucco, C; Neri, P; Papini, E; Rappuoli, R; Santucci, A; Schiavo, G | 1 |
| Cristalli, G; Eleuteri, A; Franchetti, P; Grifantini, M; Lupidi, G; Vittori, S | 1 |
| Cronstein, BN; Eberle, MA; Gruber, HE; Levin, RI | 1 |
| Caswell, AM; Leong, WS; Russell, RG | 1 |
| Melzig, M; Teuscher, E | 1 |
| Iwamoto, K; Lin, ML; Seno, M | 1 |
| Carabaza, A; Ciudad, CJ; Guinovart, JJ; Mor, A; Ricart, MD | 1 |
| Bottiglieri, T; Chanarin, I; Deacon, R; Lumb, M; Perry, J | 1 |
| Jones, M; Milliner, KJ; Rana, KK; Ward, JG; Young, RC | 1 |
| de Jong, JW; Den Boer, PJ; Grootegoed, JA; Mackenbach, P | 1 |
| Behrman, HR; Lavy, G; Polan, ML | 1 |
| Fujimori, H; Hibi, K; Sasaki, T; Senda, M; Yoshioka, M | 1 |
| Belardinelli, L; Froldi, G | 1 |
| Daly, JW; Eger, K; Hide, I; Müller, CE; Rothenhäusler, K | 1 |
| Belardinelli, L; Boykin, MT; Hill, JA; Shryock, JC | 1 |
| Blanco, J; Canela, EI; Franco, R; Lluis, C; Mallol, J | 1 |
| de Jong, JW; Opie, LH; Owen, P; van der Meer, P; van Loon, H | 1 |
| Jackson, EK; Kuan, CJ; Wells, JN | 1 |
| Barankiewicz, J; Cohen, A | 1 |
| Chalmers, AH; Coleman, M; Marshall, VR; Mohan Rao, M; Rotstein, T | 1 |
| Dhillon, GS; Honnor, RC; Londos, C | 1 |
| Church, MK; Hughes, PJ; Vardey, CJ | 1 |
| Butcher, RW; Clark, RB; Proll, MA | 1 |
| García, RA; Muñoz, A; Pérez-Aranda, A | 1 |
| Dalaker, K; Prydz, H | 1 |
| Narahashi, T; Tsunoo, A | 1 |
| Krenitsky, TA; LaFon, SW; Miller, RL; Miller, WH; Nelson, DJ | 1 |
| Belloni, FL; Gerritsen, ME; Liang, BC | 1 |
| Bowditch, J; Brown, AK; Dow, JW; Nigdikar, SV | 1 |
| Brian, EL; De Clercq, E; Pagano, JS; Smith, MS | 1 |
| Cespuglio, R; Gharib, A; Reynaud, D; Sarda, N | 1 |
| Hocart, CH; Schlunegger, UP | 1 |
| Montecucco, C; Papini, E; Rappuoli, R; Sandoná, D; Schiavo, G | 1 |
| Bingham, H; Chan, VL; Du, RP; Juranka, P; Pang, JC | 1 |
| Deussen, A; Möser, GH; Schrader, J | 1 |
| Cools, M; de Clercq, E | 2 |
| Khramtsova, SN; Pimenov, AM; Potapova, GI; Shapot, VS; Tikhonov, IuV; Toguzov, RT | 1 |
| Bürrig, KF; Kelm, MK; Kroll, K; Schrader, J | 1 |
| Allen, TM; Baer, HP; Cass, CE; Clanachan, AS; Cook, DA; Fathi-Afshar, R; Krueger, CA; Vriend, R | 1 |
| Leyimu, EO; Mehta, R; Thedford, R; Thornton, DL | 1 |
| Bittar, N; Fu, LM; Koke, JR; Sun, D; Vaughan, DM | 1 |
| David, H; Gerber, G; Schmidt, H; Siems, W; Uerlings, I; Werner, A | 1 |
| Deussen, A; Lloyd, HG; Schrader, J | 1 |
| Bontemps, F; Van den Berghe, G | 1 |
| Monteiro, EC; Ribeiro, JA | 1 |
| Des Rosiers, C; Nees, S | 1 |
| Abu-Zeid, MM; Fujimori, H; Fuke, A; Goto, A; Hirai, K; Ishii, M; Parvez, H; Sugimoto, T; Yamada, K; Yoshioka, M | 1 |
| Fredholm, BB; Lerner, UH; Sahlberg, K | 1 |
| DeClercq, E; Lin, JC; Pagano, JS | 1 |
| DeMeester, CA; Pike, MC | 1 |
| Meghji, P; Middleton, KM; Newby, AC | 1 |
| Lo, HS; Wang, CC | 1 |
| O'Brien, DR; Rall, TW | 1 |
| Pisoni, RL; Thoene, JG | 1 |
| Henson, PM; Riches, DW; Stanworth, DR; Watkins, JL | 1 |
| Holmes, EW; Manfredi, JP | 1 |
| Durston, AJ; Weijer, CJ | 1 |
| Fredholm, BB; Jonzon, B; Nilsson, J | 1 |
| Dorflinger, LJ; Schonbrunn, A | 1 |
| Feigl, EO; Kroll, K | 1 |
| Aultman, M; Gerrard, TL; Kaplan, AM; Squire, C; Strawson, J | 1 |
| De Clercq, E; Kitaoka, S; Konno, T | 1 |
| Fredholm, BB; Lindgren, E | 1 |
| Atkins, C; Bax, M; Psychoyos, S | 1 |
| Gudenzi, M; Mustafa, SJ; Nakagawa, Y | 1 |
| Kaul, R; Wenman, WM | 1 |
| Cartner, LA; Holliss, DG; Humphrey, SM | 1 |
| Hirobe, M; Katori, E; Mashino, T; Nagano, T; Yada, N; Yamane, H | 1 |
| Avila, A; Avila, JL | 1 |
| Laten, HM; Valentine, PJ; van Kast, CA | 1 |
| Berens, RL; Marr, JJ | 1 |
| Blackwell, K; Emmerson, BT; Gordon, RB | 1 |
| Belzer, FO; McAnulty, JF; Southard, JH | 2 |
| Krenitsky, TA; Miller, RL; Sabourin, CL | 1 |
| Daly, JW; Eger, K; Padgett, WL | 1 |
| Katsaros, N; Tselepi-Kalouli, E | 1 |
| Huang, P; Plunkett, W | 1 |
| Mohrman, DE | 1 |
| Borchardt, RT; Borcherding, DR; Keller, BT; Narayanan, SR; Scholtz, SA | 1 |
| De Clercq, E; Durbin, RK; Stollar, V | 1 |
| Adams, R; Drachman, DB; Kuncl, RW | 1 |
| Campochiaro, PA; Hackett, SF | 1 |
| Borchardt, RT; Borcherding, DR; Hasobe, M; Keller, BT; McKee, JG; Narayanan, S | 1 |
| Jennings, SR; Lum, CT; Tevethia, SS; Wanner, FJ | 1 |
| Bontemps, F; Hers, HG; Van den Berghe, G | 1 |
| Fujii, T; Hayashibara, H; Kizu, K; Kumazawa, Y; Nakajima, S; Saito, T | 1 |
| Kontinen, VP; Pispa, JP | 1 |
| Brown, P; Gewirtz, H; Most, AS | 1 |
| Krzanowski, JJ; Polson, JB; Sakamoto, Y; Szentivanyi, A; Urdaneta-Bohorquez, A | 1 |
| DeWitt, DF; Heller, LJ; Sparks, HV | 1 |
| McIlwain, H; Poll, JD | 1 |
| Arnold, ST; Cysyk, RL | 1 |
| Kopff, M | 1 |
| Djurhuus, R; Refsum, H; Svardal, AM; Ueland, PM | 1 |
| Barankiewicz, J; Cohen, A; Kaplinsky, C; Yeger, H | 1 |
| Müller, MM; Rumpold, H; Schopf, G | 1 |
| Adler, S; Doerjer, G; Oesch, F; Rettelbach, R | 1 |
| Jaskólski, M; Krzyzosiak, WJ; Wiewiórowski, M | 1 |
| Ehinger, BE; Fredholm, BB; Lindström, K; Perez, MT | 1 |
| Phadtare, S; Zemlicka, J | 1 |
| Goldblum, RM; Mills, GC; Schmalstieg, FC | 1 |
| Silverstein, SC; Sung, SJ | 1 |
| Rutledge, CO; Samet, MK | 2 |
| Samet, MK | 1 |
| Wolberg, G; Zimmerman, TP | 1 |
| Castaneda, M; Codd, JE; Garvin, PJ; Jellinek, M; Niehoff, M | 1 |
| Holmsen, H | 1 |
| Archer, S; Chan, VL; Ho, JH; Juranka, PF | 1 |
| Elford, HL; Lin, AL | 1 |
| Cristalli, G; Grifantini, M; Lupidi, G; Marmocchi, F; Riva, F | 1 |
| Kollman, PA; Rao, SN | 1 |
| Miras-Portugal, MT; Rotllán, P | 1 |
| Achterberg, PW; de Jong, JW | 1 |
| Teuscher, E; Weidlich, V | 1 |
| Jarvis, SM; Martin, BW; Ng, AS | 1 |
| Abe, Y; Hyodo, T; Kusachi, S; Nakatsu, T; Saito, D; Takeda, K; Tani, H; Ueeda, M | 1 |
| Hirayama, T; Kato, I; Matsuda, F; Noda, M | 1 |
| Achterberg, PW; de Jong, JW; Harmsen, E | 1 |
| Bartlett, GR | 1 |
| Carr, J; Hollingsworth, JW | 1 |
| Marshall, R | 1 |
| Rossi, A | 1 |
| Barrio, JR; Leonard, NJ; Spencer, RD; Tolman, GL; Weber, G | 1 |
| Moore, MM; Perkins, JP | 1 |
| Holmsen, H; Sixma, JJ; Trieschnigg, AC | 1 |
| Molnár, J; Prágai, B | 2 |
| Hosono, R; Kuno, S | 1 |
| Vigny, P | 1 |
| Kattlove, HE | 1 |
| Hochstadt-Ozer, J; Stadtman, ER | 1 |
| Barrnett, RJ; Beer, M; Gibson, DW | 1 |
| Del Monte, M; Nadler, HL; Rao, GJ | 1 |
| Rall, TW | 1 |
| Olszowy, J; Switzer, RL; White, MN | 1 |
| Rall, TW; Sattin, A | 1 |
| Creveling, CR; Daly, JW; Shimizu, H | 1 |
| Field, JB; Yamashita, K | 1 |
| Inamasu, M; Iwai, H; Takeyama, S | 1 |
| Kyogoku, Y; Yu, BS | 1 |
| Davies, JI; Peers, DG | 1 |
| Rammler, DH | 1 |
| Danenberg, PV; Montgomery, KA; Santi, DV | 1 |
| Park, M; Sempuku, C; Takiura, K; Yuki, H | 1 |
| Hochstadt-Ozer, J | 1 |
| Fujimoto, S; Uehara, K | 1 |
| Lerner, LM; Rossi, RR | 1 |
| Fuller, WD; Orgel, LE; Sanchez, RA | 1 |
| Ghilardelli, G; Perego, R | 1 |
| Hanamitsu, K; Yoshida, H | 1 |
| Hilz, H; Nolde, S | 1 |
| Mills, DC; Smith, JB | 1 |
| Kensler, PC; Levine, L; Salzman, EW | 1 |
| Daly, JW; Schultz, J | 2 |
| Bennett, EL; Calvin, M; Holler, E; Orme, A; Rainey, P | 1 |
| Kodama, T; Matsukado, Y; Shimizu, H | 1 |
| Formoso, C | 1 |
| Bieck, P; Vapaatalo, H; Westermann, E | 1 |
| Okayama, H; Shimizu, H | 1 |
| Daly, J; Hoffer, B; Huang, M; Skolnick, P | 1 |
| Ginsborg, BL; Hirst, GD; Maizels, JV; Walker, J | 1 |
| Ebert, R; Schwabe, U | 1 |
| Balcar, VJ; Johnston, GA | 1 |
| Kuroda, Y; McIlwain, H | 2 |
| Namm, DH | 1 |
| Carpenter, J; Messinger, K; Peck, WA | 1 |
| Beckner, SK; Gourley, DR | 1 |
| Feldman, JM; Jackson, TB | 1 |
| Lawrence, F; Shire, DJ; Waller, JP | 1 |
| Daly, JW; Gruenstein, E; Huang, M | 1 |
| Bagnara, AS; Finch, LR | 1 |
| Blume, AJ; Dalton, C; Sheppard, H | 1 |
| Campbell, JN; Phillippe, L; Pickard, MA | 1 |
| Baxter, CS; Byvoet, P | 1 |
| Iwashima, A; Nishino, H; Nose, Y | 1 |
| Carchman, RA; D'armiento, M; Johnson, GS | 1 |
| Hsu, LL; Mandel, AJ | 1 |
| Fraenkel-Conrat, H; Singer, B; Sun, L | 1 |
| Hochstadt, J | 1 |
| Lin, PP | 1 |
| Clark, RB; Gross, R; Perkins, JP; Su, YF | 1 |
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| Carvalho Junior, RN; J C Neto, AM; Martins, AY; Reis, AF; S Costa, JF; Silva Arouche, TD | 1 |
| Chen, Q; Liu, N; Long, J; Qin, F; Tang, W; Tao, R; Wang, Y; Yang, Y; Yao, S; Zhou, L | 1 |
| Koganti, P; Manimaran, M; Meena, DK; Misra, K; Negi, PS; Sharma, P; Singh, M; Tulsawani, R | 1 |
| Li, Y; Liu, J | 1 |
| Da Silva, RS; Lutte, AH; Majolo, JH | 1 |
| Clément, DA; Coelho, D; Dussurget, O; Gelin, M; Huteau, V; Labesse, G; Leseigneur, C; Lionne, C; Pochet, S | 1 |
| Brafman, DA; Brookhouser, N; Nguyen, T; Standage-Beier, K; Tekel, SJ; Wang, X | 1 |
| Brzezinski, K | 1 |
| Ding, Y; Hua, K; Liu, Y; Zhang, X; Zhang, Y | 1 |
| Chan, CT; Chan, RC; Gu, KY; Kwok, WM; Ma, C; Wang, ML; Wong, AK; Xie, HX; Xiong, QW | 1 |
| Celik, I; Duzgun, Z; Erol, M | 1 |
| Chang, P; Chen, J; Gao, L; Li, J; Liu, F; Liu, X; Lu, M; Tang, H; Tang, Y; Wang, H; Yao, L | 1 |
| D'Alonzo, D; De Fenza, M; Esposito, A; Guaragna, A | 1 |
| Chen, Z; Tang, J; Wang, F; Wang, Y; Yang, H | 1 |
| Jang, C; Jung, S; Lee, G; Mathur, L | 1 |
| Babu, YS; Demarest, JF; Gowen, BB; Julander, JG; Mathis, A; Taylor, R; Walling, DM | 1 |
| Assis, LC; da Cunha, EFF; de Almeida La Porta, F; de Castro Ramalho, T; de Castro, AA; de Jesus, JPA; Kuca, K; Nepovimova, E | 1 |
| Fu, G; Jiang, M; Qu, J; Wang, L; Wei, Z; Zhang, X | 1 |
| Babu, YS; Bielefeldt-Ohmann, H; Bowen, R; Demarest, JF; DeSpirito, M; Hartwig, A; Mathis, A; Taylor, R; Walling, DM | 1 |
| Brizzolari, A; Ciuffreda, P; Foti, MC; Lazarević, J; Santaniello, E; Saso, L | 1 |
| Collins, D; Dobo, S; Mathis, A; Sheridan, WP; Taylor, R; Walling, DM | 1 |
| Aa, J; Aa, N; Kong, X; Li, S; Lu, Z; Wang, G; Xu, C; Zhang, R; Zhang, S; Zhang, Y | 1 |
| Barbatti, M; Mansour, R; Toldo, JM | 1 |
| Colombo, G; Paladino, A; Rinaldi, S | 1 |
| Alheli Monroy Mora, K; de Lourdes Mora-García, M; Don-López, CA; García-Rocha, R; Hernández-Montes, J; Monroy-García, A; Monroy-Mora, A; Montesinos-Montesinos, JJ; Weiss-Steider, B | 1 |
| Blumenthal, RM; Cheng, X; Ciogli, A; Fiorentino, F; Hajian, T; Horton, JR; Hüben, M; Mai, A; Mazzoccanti, G; Menna, M; Ren, R; Rotili, D; Vedadi, M; Weinhold, E; Yu, D; Zhang, X; Zhou, J | 1 |
| Cao, J; Chen, J; Cheng, TL; Qiu, J; Qiu, Z; Song, L; Yuan, B; Zhang, S; Zhao, XM | 1 |
| Chen, H; Chen, Q; Fang, L; Huang, Y; Liu, J; Liu, M; Mao, C; Zuo, H | 1 |
| Blumenthal, RM; Cheng, X; Deng, Y; Hajian, T; Horton, JR; Huang, R; Iyamu, ID; Mai, A; Rotili, D; Vedadi, M; Yu, D; Zhang, X; Zhou, J | 1 |
| Barelier, S; Canard, B; Colmant, A; Coutard, B; Debart, F; Decroly, E; Delpal, A; Hausdorff, M; Nicollet, L; Touret, F; Vasseur, JJ | 1 |
| Alvarado, FJ; Berezuk, AM; Cholak, S; Haji-Ghassemi, O; Saville, JW; Subramaniam, S; Tuttle, KS; Van Petegem, F; Zhu, X | 1 |
| Chen, J; Chen, W; Liu, X; Shen, Y; Xu, X; Xu, Y | 1 |
| Brunetti, CR; Emery, RJN; Logan, SR; Seegobin, M | 1 |
| Li, XJ; Lin, L; Xie, J; Xie, L; Xu, Y; Zhang, X | 1 |
| Borde, M; Singh, SK | 1 |
42 review(s) available for adenine and adenosine
| Article | Year |
|---|---|
The structure of nucleosides in relation to their biological and and biochemical activity: a summary.
Topics: 3-Deazauridine; Adenine; Adenosine; Anti-Bacterial Agents; Azacitidine; Cytarabine; Idoxuridine; Isopentenyladenosine; Nucleosides; Pseudouridine; Puromycin; Structure-Activity Relationship; Tubercidin; Uridine | 1975 |
Membrane transport of purine and pyrimidine bases and nucleosides in animal cells.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Animals; Binding Sites; Binding, Competitive; Biological Transport, Active; Blood; Blood Cells; Cell Division; Cell Line; Cell Membrane; Cyclic AMP; Hypoxanthines; Intestinal Mucosa; Kinetics; Lipids; Nucleosides; Phosphorus; Purines; Pyrimidines; Structure-Activity Relationship; Temperature; Thymidine; Uric Acid; Uridine | 1975 |
Transport of adenine derivatives in tissues of the brain.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Animals; Biological Transport; Brain; Chlorpromazine; Cyclic AMP; Desipramine; Electric Stimulation; Glutamates; Guinea Pigs; Hypoxanthines; In Vitro Techniques; Mice; Pentobarbital | 1976 |
Immunological aspects of purine metabolism.
Topics: Adenine; Adenosine; Adenosine Deaminase; Antibody Formation; Hormones; Humans; Immunity, Cellular; Immunologic Deficiency Syndromes; Immunosuppression Therapy; Inosine; Lesch-Nyhan Syndrome; Liver; Lymphocyte Activation; Lymphocytes; Mercaptopurine; Models, Biological; Nucleoside Deaminases; Pentosyltransferases; Purine-Nucleoside Phosphorylase; Purines; Synaptic Transmission; Uridine | 1977 |
Purine metabolism and control of cell proliferation.
Topics: Adenine; Adenosine; Animals; Avian Sarcoma Viruses; Calcium; Cell Division; Cell Transformation, Viral; Chick Embryo; Cyclic GMP; DNA; Fibroblasts; Glycine; Humans; Hypoxanthines; Lectins; Lipopolysaccharides; Lymphocytes; Mitogens; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Ribose-Phosphate Pyrophosphokinase; Trypsin | 1977 |
Messenger RNA metabolism of animal cells. Possible involvement of untranslated sequences and mRNA-associated proteins.
Topics: Adenine; Adenosine; Animals; Base Sequence; Cell Nucleus; Cytoplasm; Genes; Humans; Nucleic Acid Hybridization; Nucleoproteins; Polynucleotides; Protein Biosynthesis; RNA; RNA, Messenger; Transcription, Genetic; Tritium | 1975 |
Red cell metabolism, normal and abnormal implications for red cell aging.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Kinase; Adenosine Monophosphate; Anemia, Hemolytic; Energy Metabolism; Erythrocyte Aging; Erythrocytes; Erythrocytes, Abnormal; Glycolysis; Hematologic Diseases; Humans | 1991 |
Purine salvage pathways in myocardium.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Adenosine Kinase; Adenosine Monophosphate; Animals; Guanine; Guanosine; Guanosine Monophosphate; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine Monophosphate; Myocardium; Purine Nucleosides; Purine Nucleotides | 1985 |
Nucleotide metabolism of platelets.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biological Transport, Active; Blood Platelets; Calcium; Cytoplasmic Granules; Humans; Serotonin | 1985 |
Regulatory significance of the release and action of adenine derivatives in cerebral systems.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Brain; Calcium; Carbon Radioisotopes; Cyclic AMP; Electric Stimulation; Histamine; Humans; Neurosecretion; Neurotransmitter Agents; Norepinephrine | 1972 |
The role of the membrane in the utilization of nucleic acid precursors.
Topics: Adenine; Adenosine; Bacillus subtilis; Biological Transport; Cell Membrane; Chromatography, Gel; Cytosine; DNA; Escherichia coli; Guanine; Guanosine; Hydrogen-Ion Concentration; Hypoxanthines; Inosine; Kinetics; Pentosephosphates; Pentosyltransferases; Phosphoric Acids; Purines; Pyrimidines; RNA; Thymine; Uracil; Xanthines | 1974 |
Cyclic nucleotides in higher plants?
Topics: Adenine; Adenosine; Adenylyl Cyclases; Caffeine; Cyclic AMP; Gibberellins; Phosphoric Diester Hydrolases; Plant Growth Regulators; Plants; Protein Kinases; Theophylline | 1974 |
Haemostatic functions of platelets and their disorders.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Afibrinogenemia; Aspirin; Blood Coagulation Disorders; Blood Platelet Disorders; Blood Platelets; Carbon Isotopes; Hemostasis; Humans; Microscopy, Electron; Phosphates; Phosphorus Isotopes; Platelet Adhesiveness | 1972 |
Inhibition of animal and invertebrate cell growth by naturally occurring purine bases and ribonucleosides.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Biotransformation; Cattle; Cell Division; Chromosomes; Cricetinae; Cyclic AMP; Deoxyribonucleotides; Guanine; Guanosine; Humans; Invertebrates; Mice; Mitosis; Purine Nucleosides; Purines; Pyrimidines; Rats; RNA; S-Adenosylhomocysteine; Uridine | 1980 |
The possible role of protein-carboxyl methylation in sperm motility and capacitation.
Topics: Adenine; Adenosine; Animals; Dyneins; Homocysteine; Humans; Infertility, Male; Male; Methylation; Mitochondria; Protein Methyltransferases; Protein O-Methyltransferase; Sperm Capacitation; Sperm Motility; Spermatogenesis; Spermatozoa; Testis | 1982 |
Adenosine deaminase deficiency and severe combined immunodeficiency disease.
Topics: Adenine; Adenosine; Adenosine Deaminase; B-Lymphocytes; Cells, Cultured; Cyclic AMP; Humans; Immunologic Deficiency Syndromes; Lymphocyte Activation; Nucleoside Deaminases; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Pyrimidines; Ribonucleotide Reductases; T-Lymphocytes; Tissue Distribution | 1980 |
Chemotaxis and methylation in a macrophage cell line.
Topics: Adenine; Adenosine; Animals; Blood Proteins; Cell Line; Chemotaxis, Leukocyte; Guinea Pigs; Humans; Macrophages; Methylation; Mice; Phosphatidylethanolamines; Rabbits; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1983 |
Metabolic intervention to affect myocardial recovery following ischemia.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Aminoimidazole Carboxamide; Animals; Citric Acid Cycle; Coronary Circulation; Coronary Disease; Fructosediphosphates; Glucose; Glycogen; Heart; Humans; Inosine; Myocardium; Oxidative Phosphorylation; Ribonucleosides; Ribose | 1984 |
Structure and mechanism of liver alcohol dehydrogenase, lactate dehydrogenase and glyceraldehyde-3-phosphate dehydrogenase.
Topics: Adenine; Adenosine; Alcohol Oxidoreductases; Animals; Binding Sites; Coenzymes; Glyceraldehyde-3-Phosphate Dehydrogenases; L-Lactate Dehydrogenase; Liver; Macromolecular Substances; Models, Molecular; Niacinamide; Protein Binding; Protein Conformation | 1980 |
[Oxidative reactions of the base moiety in purine nucleosides and their applications].
Topics: Adenine; Adenosine; Cyclic N-Oxides; Guanine; Oxidation-Reduction | 1995 |
Partial agonists for A(3) adenosine receptors.
Topics: Adenine; Adenosine; Adenosine A3 Receptor Agonists; Animals; Humans; Ligands; Receptor, Adenosine A3; Ribose; Structure-Activity Relationship; Xanthine | 2004 |
[The adenine riboswitch: a new gene regulation mechanism].
Topics: Adenine; Adenosine; Bacteria; Base Sequence; Crystallography, X-Ray; Gene Expression Regulation; Homeostasis; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Ribosomes; RNA; RNA, Messenger | 2006 |
[Attention-getting sexually transmitted diseases: Hepatitis B].
Topics: Adenine; Adenosine; Antiviral Agents; Comorbidity; Drug Therapy, Combination; Genotype; Guanine; Guanosine; Hepatitis B; Hepatitis B virus; HIV Infections; Humans; Lamivudine; Organophosphonates; Reverse Transcriptase Inhibitors; Sexually Transmitted Diseases, Viral | 2007 |
Current developments in the synthesis and biological activity of aza-C-nucleosides: immucillins and related compounds.
Topics: Adenine; Adenosine; Aza Compounds; Glycoside Hydrolases; N-Glycosyl Hydrolases; Nucleosides; Purine Nucleosides; Purine-Nucleoside Phosphorylase; Pyrimidinones; Pyrroles; Pyrrolidines | 2008 |
A2A adenosine receptor and its modulators: overview on a druggable GPCR and on structure-activity relationship analysis and binding requirements of agonists and antagonists.
Topics: Adenine; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Drug Design; Drug Partial Agonism; Humans; Ligands; Neuroprotective Agents; Protein Conformation; Radiopharmaceuticals; Receptor, Adenosine A2A; Structure-Activity Relationship; Xanthines | 2008 |
Current status of chemically synthesized inhibitors of Ebola virus.
Topics: Adenine; Adenosine; Amides; Antiviral Agents; Cytosine; Drug Discovery; Ebolavirus; Hemorrhagic Fever, Ebola; Humans; Organophosphonates; Patents as Topic; Purine Nucleosides; Pyrazines; Pyrrolidines | 2014 |
The Immucillins: Design, Synthesis and Application of Transition- State Analogues.
Topics: Adenine; Adenosine; Animals; Enzyme Inhibitors; Humans; N-Glycosyl Hydrolases; Protein Binding; Purine-Nucleoside Phosphorylase; Pyrrolidines; Substrate Specificity; Thermodynamics | 2015 |
C-Nucleosides To Be Revisited.
Topics: Adenine; Adenosine; Alanine; Animals; Antineoplastic Agents; Antiviral Agents; Humans; Nucleosides; Nucleotides; Pseudouridine; Purine Nucleosides; Pyrrolidines; Triazines | 2016 |
Ebola Virus Infection: Review of the Pharmacokinetic and Pharmacodynamic Properties of Drugs Considered for Testing in Human Efficacy Trials.
Topics: Adenine; Adenosine; Amides; Animals; Antiviral Agents; Disease Outbreaks; Ebolavirus; Healthy Volunteers; Hemorrhagic Fever, Ebola; Humans; Models, Animal; Purine Nucleosides; Pyrazines; Pyrrolidines | 2016 |
Nucleic Acid Modifications in Regulation of Gene Expression.
Topics: 5-Methylcytosine; Adenine; Adenosine; Animals; Cytidine; DNA; DNA Methylation; Gene Expression Regulation; Humans; Pseudouridine; RNA | 2016 |
Gas-Phase Femtosecond Particle Spectroscopy: A Bottom-Up Approach to Nucleotide Dynamics.
Topics: Adenine; Adenosine; DNA; Equipment Design; Gases; Ions; Kinetics; Nucleotides; Photochemical Processes; Spectrum Analysis; Time Factors | 2016 |
Bacterial DNA Methylation and Methylomes.
Topics: 5-Methylcytosine; Adenine; Adenosine; Alphaproteobacteria; Cell Lineage; DNA Methylation; DNA Replication; Gammaproteobacteria; Gene Expression Regulation, Bacterial; Genome, Bacterial | 2016 |
Will There Be a Cure for Ebola?
Topics: Adenine; Adenosine; Adenosine Monophosphate; Africa, Western; Alanine; Animals; Antiviral Agents; Disease Outbreaks; Ebolavirus; Hemorrhagic Fever, Ebola; Humans; Purine Nucleosides; Pyrrolidines; Ribonucleotides | 2017 |
8-Oxo-7,8-dihydroadenine and 8-Oxo-7,8-dihydroadenosine-Chemistry, Structure, and Function in RNA and Their Presence in Natural Products and Potential Drug Derivatives.
Topics: Adenine; Adenosine; Biological Products; Oxidation-Reduction; Purine Nucleotides; RNA; Spectrophotometry | 2017 |
Comprehensive Review on Ebola (EBOV) Virus: Future Prospects.
Topics: Adenine; Adenosine; Africa, Western; Animals; Antiviral Agents; Disease Outbreaks; Drug Discovery; Ebolavirus; Hemorrhagic Fever, Ebola; Humans; Immune System; Purine Nucleosides; Pyrrolidines; Virus Replication | 2018 |
The path towards effective antivirals against rabies.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Drug Repositioning; Humans; Post-Exposure Prophylaxis; Pyrazines; Pyrrolidines; Rabies; Rabies virus | 2019 |
New Nucleoside Analogues for the Treatment of Hemorrhagic Fever Virus Infections.
Topics: Adenine; Adenosine; Alanine; Amides; Antiviral Agents; Base Pairing; Ebolavirus; Guanine; Hemorrhagic Fevers, Viral; Humans; Nucleotides; Phosphoric Acids; Pyrazines; Triazines | 2019 |
Aptamer-based strategies for recognizing adenine, adenosine, ATP and related compounds.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Aptamers, Nucleotide; Biosensing Techniques | 2020 |
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Amino Acid Motifs; Animals; Crystallography, X-Ray; Databases, Protein; Homocysteine; Humans; Ligands; Methylation; Molecular Conformation; NAD; Nucleotides; Protein Binding; Protein Domains; Protein Folding; Software | 2020 |
An update on the progress of galidesivir (BCX4430), a broad-spectrum antiviral.
Topics: Adenine; Adenosine; Animals; Antiviral Agents; Clinical Trials, Phase I as Topic; Drug Evaluation, Preclinical; Marburgvirus; Nucleosides; Pyrrolidines; SARS-CoV-2 | 2021 |
Targeting IGF2BP3 in Cancer.
Topics: Adenine; Adenosine; Eukaryota; Humans; Neoplasms; RNA | 2023 |
Emerging Roles for DNA 6mA and RNA m6A Methylation in Mammalian Genome.
Topics: Adenine; Adenosine; Animals; DNA; Mammals; Methylation; RNA | 2023 |
1 trial(s) available for adenine and adenosine
| Article | Year |
|---|---|
Pharmacokinetics and Safety of the Nucleoside Analog Antiviral Drug Galidesivir Administered to Healthy Adult Subjects.
Topics: Adenine; Adenosine; Animals; Antiviral Agents; Healthy Volunteers; Humans; Nucleosides; Pyrrolidines; Zika Virus; Zika Virus Infection | 2022 |
1012 other study(ies) available for adenine and adenosine
| Article | Year |
|---|---|
Identification of critical ligand binding determinants in Mycobacterium tuberculosis adenosine-5'-phosphosulfate reductase.
Topics: Catalytic Domain; Drug Design; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Ligands; Magnesium; Models, Molecular; Mycobacterium tuberculosis; Oxidoreductases Acting on Sulfur Group Donors; Pseudomonas aeruginosa; Static Electricity; Substrate Specificity | 2009 |
Inhibition of CTP synthase from Escherichia coli by xanthines and uric acids.
Topics: Carbon-Nitrogen Ligases; Enzyme Inhibitors; Escherichia coli; Kinetics; Methylation; Structure-Activity Relationship; Uric Acid; Xanthines | 2010 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Specific interactions between adenosine and streptavidin/avidin.
Topics: Adenosine; Aptamers, Nucleotide; Avidin; Fluorescent Dyes; Kinetics; Protein Binding; Spectrometry, Fluorescence; Streptavidin | 2012 |
Rational Design of Selective Adenine-Based Scaffolds for Inactivation of Bacterial Histidine Kinases.
Topics: Adenine; Adenosine Triphosphate; Anti-Bacterial Agents; Aspartic Acid; Bacteria; Drug Design; Histidine Kinase; HSP90 Heat-Shock Proteins; Models, Molecular; Molecular Docking Simulation; Structure-Activity Relationship | 2017 |
Effect of pH and ionic strength on the catalytic and allosteric properties of native and chemically modified ox liver mitochondrial glutamate dehydrogenase.
Topics: Adenine; Adenine Nucleotides; Adenosine; Allosteric Regulation; Allosteric Site; Animals; Cattle; Dinitrophenols; Glutamate Dehydrogenase; Guanine; Guanine Nucleotides; Guanosine; Hydrogen-Ion Concentration; Kinetics; Mitochondria, Liver; Osmolar Concentration; Protein Binding | 1975 |
Control of differentiation in streptomycetes: involvement of extrachromosomal deoxyribonucleic acid and glucose repression in aerial mycelia development.
Topics: Adenine; Adenosine; Depression, Chemical; DNA, Bacterial; Ethidium; Extrachromosomal Inheritance; Glucose; Guanosine; Hydrogen-Ion Concentration; Puromycin; Spores, Bacterial; Streptomyces | 1976 |
Adenosine phosphyorylase activity as distinct from inosine-guanosine phosphorylase activity in Sarcoma 180 cells and rat liver.
Topics: Adenine; Adenosine; Animals; Chloromercuribenzoates; Guanine; Hydrogen-Ion Concentration; Inosine; Kinetics; Liver; Pentosyltransferases; Rats; Sarcoma 180 | 1976 |
Pharmacological studies with adenine, adenosine and some phosphorylated derivatives on guinea-pig tracheal muscle.
Topics: Adenine; Adenosine; Animals; Dipyridamole; Guinea Pigs; Imidazoles; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth; Propranolol; Quinidine; Theophylline; Trachea | 1976 |
Adenosine 3':5'-cyclic monophosphate-binding proteins in bovine and rat tissues.
Topics: Adenine; Adenine Nucleotides; Adenosine; Aging; Animals; Binding, Competitive; Carrier Proteins; Cattle; Chromatography, Agarose; Chromatography, DEAE-Cellulose; Cyclic AMP; Histones; Hydrogen-Ion Concentration; Liver; Molecular Weight; Protein Kinases; Rats; Trypsin | 1976 |
Reversible inhibition of interferon-induced antiviral state by deoxyadenosine.
Topics: Adenine; Adenosine; Animals; Cell Nucleolus; Chick Embryo; Culture Techniques; Dactinomycin; Deoxyadenosines; Drug Antagonism; Interferons; Protein Biosynthesis; RNA; Sindbis Virus; Vesicular stomatitis Indiana virus | 1976 |
Kinetics and mechanism of carbon-8 methylation of purine bases and nucleosides by methyl radical.
Topics: Adenine; Adenosine; Caffeine; Guanine; Guanosine; Hot Temperature; Hydrogen-Ion Concentration; Hypoxanthines; Inosine; Kinetics; Methods; Methylation; Photochemistry; Purine Nucleosides | 1977 |
Characterization of the residual adenosine deaminating activity in the spleen of a patient with combined immunodeficiency disease and adenosine deaminase deficiency.
Topics: Adenine; Adenosine; Adenosine Deaminase; Cross Reactions; Hydrogen-Ion Concentration; Immunologic Deficiency Syndromes; Kinetics; Nucleoside Deaminases; Spleen | 1978 |
[Interaction of intracellular RNAase from Aspergillus clavatus with derivatives of its substrates].
Topics: Acylation; Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aspergillus; Binding Sites; Hydrogen-Ion Concentration; Isomerism; Ribonucleases; Ribosemonophosphates; Spectrophotometry, Ultraviolet; Substrate Specificity | 1978 |
A study on the sequestration of adenosine and its conversion to adenine by the cyclic AMP-adenosine binding protein/S-adenosylhomocysteinase from mouse liver.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosylhomocysteinase; Animals; Carrier Proteins; Cyclic AMP; Hydrogen-Ion Concentration; Hydrolases; Liver; S-Adenosylhomocysteine; Temperature; Time Factors | 1979 |
Studies in vitro on the effect of adenosine, adenine and NAD on guinea pig myometrium in the presence of exogenously applied PGE2.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Female; Guinea Pigs; Indomethacin; Muscle Contraction; Myometrium; NAD; Prostaglandins E; Uterus | 1979 |
Application of uracil-bonded silica gel to the separation of adenine and its derivatives, and to poly(A)-containing RNA.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Chromatography, Gel; Poly A; Rabbits; Reticulocytes; RNA; Silicon Dioxide; Uracil | 1979 |
Catabolism of adenosine 5'-monophosphate in promastigotes of Leishmania tropica.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Hypoxanthines; Inosine; Leishmania; Nucleotidases; Purine-Nucleoside Phosphorylase | 1978 |
A coupled optical assay for determination of adenine in mixtures.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Monophosphate; Kinetics; Medicago sativa; Plants; Purine-Nucleoside Phosphorylase; Ribonucleosides; Ribonucleotides; Spectrophotometry, Ultraviolet | 1979 |
Purine base transport in Neurospora crassa.
Topics: Adenine; Adenosine; Biological Transport, Active; Cytosine; Guanine; Hypoxanthines; Kinetics; Mutation; Neurospora; Neurospora crassa; Purines; Recombination, Genetic; Spores, Fungal | 1975 |
A cellular-biochemical evaluation of gastric body mucosa and muscular layer in patients with different basal acid outputs.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; DNA; Gastric Juice; Gastric Mucosa; Humans; Muscle, Smooth; Peptic Ulcer; Phospholipids; RNA; Secretory Rate | 1976 |
Affinity labeling of AMP-ADP sites in heart phosphofructokinase by 5-p-fluorosulfonylbenzoyl adenosine.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Affinity Labels; Allosteric Site; Animals; Myocardium; Phosphofructokinase-1; Sheep | 1978 |
Mutants of chinese hamster cells resistant to adenosine.
Topics: Adenine; Adenosine; Aminohydrolases; Animals; Carbon Radioisotopes; Cell Count; Cell Division; Cell Line; Cell-Free System; Cricetinae; Drug Resistance; Female; Guanine; Hypoxanthines; Inosine; Inosine Nucleotides; Ketone Oxidoreductases; Mutation; Ovary; Pentosyltransferases; Phosphotransferases; Pyrimidines; Tritium | 1975 |
Functional compartments of adenine nucleotides serving as precursors of adenosine 3',5'-monophosphate in mouse cerebral cortex.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Cerebral Cortex; Cyclic AMP; Histamine; Mice; Mice, Inbred Strains; Norepinephrine; Time Factors; Veratrine | 1975 |
Action of various adenine derivatives on cerebellar Purkinje cells.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cyclic AMP; Electrophysiology; Iontophoresis; Male; Purkinje Cells; Rats; Structure-Activity Relationship | 1975 |
A potent depressant action of adenine derivatives on cerebral cortical neurones.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Cerebral Cortex; Cyclic AMP; Depression, Chemical; Glutamates; In Vitro Techniques; Inosine; Iontophoresis; Male; Neurons; Rats | 1975 |
Separation of cyclic AMP from adenine and hypoxanthine, their nucleosides and nucleotides by high voltage paper electrophoresis.
Topics: Adenine; Adenine Nucleotides; Adenosine; Cyclic AMP; Electrophoresis, Paper; Hypoxanthines; Inosine; Inosine Nucleotides; Methods; Ribonucleosides; Ribonucleotides; Time Factors | 1975 |
Factors influencing the effect of hormones on the accumulation of cyclic AMP in cultured human astrocytoma cells.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Astrocytoma; Catecholamines; Cells, Cultured; Cyclic AMP; Dipyridamole; Dopamine; Drug Interactions; Epinephrine; Humans; Isoproterenol; Norepinephrine; Propranolol; Prostaglandin Antagonists; Prostaglandins; Structure-Activity Relationship; Theophylline; Time Factors; Tritium | 1975 |
The relation of endogenous adenosine cyclic 3':5'-monophosphate to the antagonistic effects of adenosine and colchicine on cell shape.
Topics: Adenine; Adenosine; Animals; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Colchicine; Cricetinae; Cyclic AMP; Lung; Simian virus 40 | 1975 |
Aggregation and release in thrombocytes of the duck.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Platelets; Collagen; Ducks; Glucuronidase; L-Lactate Dehydrogenase; Phosphoric Monoester Hydrolases; Platelet Adhesiveness; Platelet Aggregation; Serotonin | 1975 |
Interrelationship between poly (ADP-Rib) synthesis, intracellular NAD levels, and muscle or cartilage differentiation from mesodermal cells of embryonic chick limb.
Topics: Adenine; Adenosine; Animals; Cartilage; Cell Differentiation; Cells, Cultured; Chick Embryo; Chromatin; Chromatography, Agarose; Muscles; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Thymidine; Time Factors | 1975 |
Comparative effects of adenosine and adenine and guanine nucleotides on drug biotransformation in rats.
Topics: Adenine; Adenosine; Aniline Compounds; Animals; Biotransformation; Bucladesine; Cyclic AMP; Guanine Nucleotides; Hexobarbital; In Vitro Techniques; Liver; Male; Microsomes, Liver; Pharmaceutical Preparations; Rats; Sleep; Theophylline | 1975 |
Intracellular formation of analogs of cyclic AMP. Studies with brain slices labeled with radioactive derivatives of adenine and adenosine.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Animals; Cerebral Cortex; Cyclic AMP; Deoxyadenosines; Guinea Pigs; In Vitro Techniques; Male; Veratridine | 1975 |
Characterization of the metabolism of exogenous cyclic AMP by perfused rat heart and incubated prepubertal rat ovary.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cyclic AMP; Female; Metabolic Clearance Rate; Myocardium; Ovary; Phosphoric Diester Hydrolases; Rats; Theophylline; Time Factors | 1975 |
Effect of bredinin and its aglycone on L5178Y cells.
Topics: Adenine; Adenosine; Animals; Antibiotics, Antineoplastic; Antifungal Agents; Candida albicans; Cell Line; DNA, Neoplasm; Dose-Response Relationship, Drug; Guanine; Guanine Nucleotides; Guanosine; Guanosine Monophosphate; Imidazoles; Mice; Rats; Ribonucleosides; RNA, Neoplasm | 1975 |
Free radicals from purine nucleosides after hydroxyl radical attack.
Topics: Adenine; Adenosine; Caffeine; Deoxyadenosines; Electron Spin Resonance Spectroscopy; Free Radicals; Guanosine; Hydroxylation; Imidazoles; Inosine; Purine Nucleosides; Radiation Effects | 1976 |
Neuroblastoma cell adenylate cyclase: direct activation by adenosine and prostaglandins.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Adenosine; Adenylyl Cyclases; Cell Line; Cyclic GMP; Dopamine; Isoproterenol; Kinetics; Neoplasms, Experimental; Neuroblastoma; Norepinephrine; Papaverine; Prostaglandins E; Prostaglandins F; Theophylline | 1976 |
Turnover at nicotinamide adenine dinucleotide in cultures of human cells.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Cell Line; Kinetics; Mathematics; NAD | 1976 |
Release of adenosine-like material from isolated perfused dog adipose tissue following sympathetic nerve stimulation and its inhibition by adrenergic alpha-receptor blockade.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Adipose Tissue; Animals; Cyclic AMP; Dogs; Electric Stimulation; Female; Glycerol; Inosine; Perfusion; Phentolamine; Sympathetic Nervous System | 1976 |
Quantitative estimation of 3'5' cyclic AMP phosphodiesterase using anion exchange resin in a batch process.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Adenosine; Adenosine Monophosphate; Anion Exchange Resins; Binding Sites; Chromatography, Ion Exchange; Cyclic AMP; Ethanol; Guanosine; Hypoxanthines; Inosine; Magnesium; Phosphoric Diester Hydrolases; Protein Binding | 1976 |
Stimulation of ribonuclease activity and its isoenzymes in germinating seeds of cowpea (Vigna sinensis) by gibberellic acid and adenosine-3',5-cyclic monophosphate.
Topics: Adenine; Adenine Nucleotides; Adenosine; Cyclic AMP; Cycloheximide; Dactinomycin; Gibberellins; Isoenzymes; Plant Proteins; Ribonucleases; RNA; Seeds; Theophylline | 1976 |
Altered brain cyclic AMP-responses in rats reared in enriched or impoverished environments.
Topics: Adenine; Adenosine; Animals; Cyclic AMP; Histamine; Isoproterenol; Male; Norepinephrine; Prostaglandins E; Rats; Social Environment; Social Isolation; Telencephalon | 1976 |
Fluorimetric determination of adenine and adenosine and its nucleotides by high-performance liquid chromatography.
Topics: Adenine; Adenine Nucleotides; Adenosine; Chromatography, High Pressure Liquid; Cyclic AMP; Methods; Microchemistry; Spectrometry, Fluorescence | 1976 |
Incorporation of purines and pyrimidines in axenically grown Entamoeba histolytica.
Topics: Adenine; Adenosine; Animals; Cytidine; Cytosine; Entamoeba histolytica; Purine Nucleosides; Purines; Pyrimidine Nucleosides; Pyrimidines | 1976 |
Incorporation of adenosine into ATP: formation of compartmentalized ATP.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Hypoxanthines; Liver; Liver Neoplasms; Mice; Mice, Nude; Neoplasms, Experimental | 1976 |
Characterization of a cell culture model for the study of adenosine deaminase- and purine nucleoside phosphorylase-deficient immunologic disease.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Bucladesine; Cell Line; Cell Survival; Cyclic AMP; Dexamethasone; Formycins; Immunologic Deficiency Syndromes; Inosine; Nucleoside Deaminases; Pentosyltransferases; Purine-Nucleoside Phosphorylase; Uridine | 1976 |
[Effect of 2,6-diaminopurine resistance mutations on adenine and adenosine assimilation by cells of an adenine-dependent strain of Escherichia coli K-12].
Topics: Adenine; Adenosine; Adenosine Kinase; Escherichia coli; Mutation; Phosphotransferases; Purines; Recombination, Genetic | 1976 |
Effects of ACTH, adenyl compounds, and methylxanthines on goldfish erythrophores in culture.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adrenocorticotropic Hormone; Animals; Bucladesine; Caffeine; Cells, Cultured; Chromatophores; Cyclic AMP; Cytoplasmic Granules; Dose-Response Relationship, Drug; Goldfish; Kinetics; Microscopy, Phase-Contrast; Pigments, Biological; Theophylline; Xanthines | 1977 |
Adenine and adenosine are toxic to human lymphoblast mutants defective in purine salvage enzymes.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Cell Line; Humans; Hypoxanthine Phosphoribosyltransferase; Lymphocytes; Nucleotides; Pentosyltransferases; Phosphotransferases | 1977 |
Quantitative extraction, separation, and recovery of adenine-derived radioactivity in bases, nucleosides, and nucleotides from blood platelets using PEI-cellulose thin-layer chromatography.
Topics: Adenine; Adenine Nucleotides; Adenosine; Blood Platelets; Cellulose; Chromatography, Thin Layer; Cyclic AMP; Humans; Inosine Monophosphate; Purines | 1977 |
The effect of cyclic AMP on human colony forming cell and colony stimulating factor production.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Bone Marrow; Bone Marrow Cells; Bucladesine; Cell Division; Cell Separation; Clone Cells; Colony-Stimulating Factors; Culture Techniques; Cyclic AMP; Glycoproteins; Humans | 1977 |
An adenosine 3':5'-monophosphate/adenosine binding protein from mouse liver. A study of its interaction with synthetic and naturally occurring adenosine derivatives.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Carrier Proteins; Cyclic AMP; Kinetics; Liver; Mice; Structure-Activity Relationship | 1978 |
Entamoeba histolytica: uptake of purine bases and nucleosides during axenic growth.
Topics: Adenine; Adenosine; Animals; Culture Media; Entamoeba histolytica; Guanine; Guanosine; Hypoxanthines; Inosine; Purine Nucleosides; Purines | 1978 |
Erythro-9-(2-hydroxy-3-nonyl)adenine as a specific inhibitor of herpes simplex virus replication in the presence and absence of adenosine analogues.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Deoxyadenosines; DNA Replication; DNA, Viral; Drug Synergism; HeLa Cells; Nucleoside Deaminases; RNA, Viral; Simplexvirus; Vidarabine; Viral Proteins; Virus Replication | 1978 |
Uptake and release of adenosine in isolated rat fat cells.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adipose Tissue; Animals; Cyclic AMP; Isoproterenol; Lipid Metabolism; Methoxamine; Norepinephrine; Nucleotidases; Papaverine; Rats; Theophylline | 1979 |
Cyclic AMP-adenosine binding protein/S-adenosylhomocysteinase from mouse liver. A fraction of adenosine bound is converted to adenine.
Topics: Adenine; Adenosine; Adenosine Deaminase; Animals; Carrier Proteins; Chromatography, Gel; Chromatography, Thin Layer; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Homocysteine; Hydrolases; Hydrolysis; In Vitro Techniques; Inosine; Liver; Mice; Protein Denaturation; Ribose; S-Adenosylhomocysteine | 1979 |
Release of 3H-nucleosides from 3H-adenine labelled hypothalamic synaptosomes.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Antimycin A; Chromatography, Gel; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cyclic AMP; Electric Stimulation; Energy Metabolism; Glucose; Hypothalamus; Hypoxia; Male; Nucleosides; Perfusion; Rats; Secretory Rate; Synaptosomes; Veratridine | 1979 |
Evidence for two adenine derivative receptors in rat ileum which are not involved in the nonadrenergic, noncholinergic response.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Electric Stimulation; Ileum; In Vitro Techniques; Male; Nicotine; Parasympathetic Nervous System; Rats; Receptors, Cell Surface; Sympathetic Nervous System; Theophylline | 1979 |
Adenine formation from adenosine by mycoplasmas: adenosine phosphorylase activity.
Topics: Acholeplasma laidlawii; Adenine; Adenosine; Animals; Cell Line; Cells, Cultured; Cricetinae; Humans; Kinetics; Mice; Mycoplasma; Pentosyltransferases; Purine-Nucleoside Phosphorylase; Species Specificity; Time Factors | 1975 |
The photochemistry of purine components of nucleic acids. I. The efficiency of photolysis of adenine and guanine derivatives in aqueous solution.
Topics: Adenine; Adenine Nucleotides; Adenosine; Guanine; Guanine Nucleotides; Guanosine; Hydrogen-Ion Concentration; Oxygen; Partial Pressure; Photolysis; Quantum Theory; Spectrophotometry, Ultraviolet; Temperature; Time Factors | 1975 |
Deoxyadenosine triphosphate as a potentially toxic metabolite in adenosine deaminase deficiency.
Topics: Adenine; Adenosine; Adenosine Deaminase; Deoxyadenine Nucleotides; Erythrocytes; Humans; Immunologic Deficiency Syndromes; Monocytes; Nucleoside Deaminases | 1978 |
Toxicities of adenosine and 2'-deoxyadrenosine in L cells treated with inhibitors of adenosine deaminase.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Anti-Bacterial Agents; Azepines; Deoxyadenosines; Deoxyribonucleosides; Fibroblasts; L Cells; Mice; Nucleoside Deaminases; Vidarabine | 1977 |
Uptake and metabolism of purine nucleosides and nucleotides in isolated frog skeletal muscle.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Anura; Binding, Competitive; Biological Transport; Biological Transport, Active; Hypoxanthines; Inosine; Inosine Monophosphate; Kinetics; Muscles; Purine Nucleosides; Rana pipiens; Ribonucleotides; Temperature | 1977 |
Analysis of adenosine-mediated pyrimidine starvation using cultured wild-type and mutant mouse T-lymphoma cells.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Azepines; Cell Line; Cells, Cultured; Deoxyribonucleosides; Hypoxanthine Phosphoribosyltransferase; Lymphoma, Non-Hodgkin; Mice; Mutation; Phosphoribosyl Pyrophosphate; Pyrimidines; T-Lymphocytes | 1978 |
Purine reutilization in phytohemagglutinin-stimulated human T-lymphocytes.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Adenosine Deaminase; Adenosine Kinase; Guanine; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Kinetics; Lectins; Lymphocyte Activation; Nucleotides; T-Lymphocytes | 1978 |
Limited effect of erythrocyte and plasma infusions in adenosine deaminase deficiency.
Topics: Adenine; Adenosine; Adenosine Deaminase; Blood Transfusion; Child, Preschool; Deoxyadenosines; Erythrocyte Transfusion; Erythrocytes; Humans; Immunologic Deficiency Syndromes; Infant; Lymphocytes; Male; Nucleoside Deaminases | 1978 |
Action of adenosine on chloride active transport of isolated frog cornea.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Animals; Anura; Biological Transport, Active; Chlorides; Cornea; Epinephrine; Polyphloretin Phosphate; Propranolol; Rana catesbeiana; Ribose; Theophylline | 1979 |
De novo purine ribonucleotide biosynthesis in adult Angiostrongylus cantonensis (Nematoda: Metastrongyloidea).
Topics: Adenine; Adenosine; Angiostrongylus; Animals; Female; Guanine; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; Male; Metastrongyloidea; Purine Nucleotides | 1979 |
A conditional antimutator in E. coli.
Topics: Adenine; Adenosine; Chromosomes, Bacterial; Escherichia coli; Gene Frequency; Genes; Genes, Recessive; Mutation; Nitrosoguanidines; Phenotype; Temperature; Ultraviolet Rays | 1977 |
Crypticity of periplasmic enzymes. Involvement of protein b in the permeability of the outer membranes of Escherichia coli.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Bacterial Proteins; Biological Transport; Cell Membrane Permeability; Escherichia coli; Kinetics; Membrane Proteins; Mutation | 1978 |
A patient with purine nucleoside phosphorylase deficiency: enzymological and metabolic aspects.
Topics: Adenine; Adenosine; Child; Erythrocytes; Female; Humans; Hypoxanthines; Inosine; Pentosyltransferases; Phosphoribosyl Pyrophosphate; Purine-Nucleoside Phosphorylase; Purines; Time Factors | 1977 |
In vitro of adenosine on lymphocytes and erythrocytes from horses with combined immunodeficiency.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Animals; Erythrocytes; Female; Horse Diseases; Horses; Immunologic Deficiency Syndromes; Lymphocytes; Male; Mitogens; Nucleotides; Thymidine; Time Factors; Uridine | 1979 |
Inhibition of methylation by adenosine in adenosine deaminase-inhibited, phytohemagglutinin-stimulated human lymphocytes.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; DNA; Homocysteine; Humans; Lymphocyte Activation; Methylation; Nucleoside Deaminases; Phytohemagglutinins; S-Adenosylhomocysteine; S-Adenosylmethionine | 1979 |
Uptake and release of adenosine by cultured astrocytoma cells.
Topics: Adenine; Adenosine; Astrocytoma; Biological Transport; Cell Line; Humans; Kinetics | 1979 |
Adenine cycle in hepatopancreocytes of Helix pomatia (Gastropoda).
Topics: Adenine; Adenosine; Animals; Cells, Cultured; Culture Media; Formates; Glycine; Helix, Snails; Hibernation; Liver; Pancreas; Purine Nucleotides | 1979 |
Inhibition of immune cell function by adenosine: biochemical studies.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenine; Adenosine; Animals; Cytotoxicity, Immunologic; Homocysteine; Imidazoles; Lymphocytes; Methionine; Mice; S-Adenosylmethionine; Theophylline; Uridine | 1979 |
Uptake of adenosine in human erythrocytes.
Topics: Adenine; Adenosine; Biological Transport; Erythrocytes; Humans; Kinetics; Temperature | 1979 |
An 15N NMR study of adenine-uracil base pair in a non-aqueous solvent.
Topics: Adenine; Adenosine; Base Composition; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Nitrogen Isotopes; Nucleic Acid Conformation; Solvents; Uracil | 1979 |
Purine salvage at the cholinergic nerve endings of the Torpedo electric organ: the central role of adenosine.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Cholinergic Fibers; Electric Organ; Fishes; Hypoxanthines; Inosine; Synaptosomes | 1979 |
Inhibition of Dictyostelium discoideum beta-glucosidase by purines.
Topics: Adenine; Adenosine; Dictyostelium; Glucose; Glucosidases; Guanosine; Hypoxanthines; Inosine; Kinetics; Myxomycetes; Purines | 1977 |
Inhibition of mouse molar morphogenesis in vitro by hadacidin.
Topics: Adenine; Adenosine; Animals; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Formaldehyde; Glycine; Mice; Mitosis; Molar; Morphogenesis; Odontogenesis; Organ Culture Techniques; Teratogens; Tooth Germ | 1978 |
Determination of the mutational block in the adenine biosynthetic pathway of yeast Torulopsis bovina.
Topics: Adenine; Adenosine; Candida; Hypoxanthines; Mutation | 1979 |
Depletion of platelet amine storage granules by the antithrombotic agent, suloctidil.
Topics: Adenine; Adenosine; Blood Platelets; Cytoplasmic Granules; Energy Metabolism; Fibrinolytic Agents; Platelet Aggregation; Propanolamines; Serotonin | 1977 |
Possible regulation of macromolecular biosynthesis in mammalian cells by a novel dinucleoside polyphosphate (HS3) produced during step-down growth conditions.
Topics: Adenine; Adenosine; Cell Line; Cycloheximide; Dactinomycin; DNA; Glutamine; Hypoxanthines; Nucleotides; Protein Biosynthesis; RNA | 1977 |
Synthesis and biological activities of some N6- and N9-carbamoyladenines and related ribonucleosides.
Topics: Adenine; Adenosine; Animals; Cell Division; Cell Line; Chemical Phenomena; Chemistry; Leukemia L1210; Mice; Structure-Activity Relationship | 1977 |
Experimental modulation of PRPP availability for ribonucleotide synthesis from hypoxanthine in human skin fibroblast cultures.
Topics: Adenine; Adenosine; Cell Line; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Kinetics; Methylene Blue; Orotic Acid; Pentosephosphates; Phosphoribosyl Pyrophosphate; Ribonucleotides | 1978 |
Uptake and metabolism of adenosine by pig aortic endothelial and smooth-muscle cells in culture.
Topics: Adenine; Adenosine; Animals; Aorta, Thoracic; Biological Transport; Cells, Cultured; Dipyridamole; Endothelium; Inosine; Kinetics; Muscle, Smooth; Papaverine; Swine | 1978 |
Iontophoresis of vidarabine monophosphate into rabbit eyes.
Topics: Adenine; Adenosine; Animals; Aqueous Humor; Cornea; Eye; Hypoxanthines; Iontophoresis; Iris; Lens, Crystalline; Ophthalmic Solutions; Rabbits; Vidarabine | 1978 |
The development of tachyphylaxis to electrical stimulation in guinea-pig ileal longitudinal muscles and the possible participation of adenosine and adenine nucleotides.
Topics: Acetylcholine; Adenine; Adenine Nucleotides; Adenosine; Animals; Dipyridamole; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Tachyphylaxis; Theophylline | 1978 |
Cytotoxic and metabolic effects of adenosine and adenine on human lymphoblasts.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Azepines; Cell Division; Humans; Lymphocytes; Phosphoribosyl Pyrophosphate; Pyrimidine Nucleotides; Ribonucleosides; Uridine | 1978 |
Adenine and adenosine metabolism in intact erythrocytes deficient in adenosine monophosphate-pyrophosphate phosphoribosyltransferase: a study of two families.
Topics: Adenine; Adenine Nucleotides; Adenine Phosphoribosyltransferase; Adenosine; Adult; Child; Child, Preschool; Erythrocytes; Female; Humans; Hypoxanthines; In Vitro Techniques; Inosine Monophosphate; Male; Pentosyltransferases | 1978 |
Role of adenine phosphoribosyltransferase in adenine uptake in wild-type and APRT- mutants of CHO.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Biological Transport; Cell Line; Kinetics; Mutation; Pentosyltransferases | 1978 |
[The influence of adenine, adenosine and adenylic nucleotides on the mutagenic action of hydroxylamine].
Topics: Adenine; Adenosine; Adenosine Monophosphate; Deoxyadenosines; Drug Interactions; Escherichia coli; Hydroxylamines; Mutagens; Phosphates | 1975 |
Production of a precursor to the pyrimidine moiety of thiamine.
Topics: Adenine; Adenosine; Drug Stability; Enterobacter; Escherichia coli; Imidazoles; Mutation; Pyrimidines; Ribonucleosides; Salmonella typhimurium; Temperature; Thiamine; Thiamine Pyrophosphate | 1976 |
[Effect of adenine, adenosine and adenylic nucleotides on the mutagenic action of hydroxylamine].
Topics: Adenine; Adenosine; Adenosine Monophosphate; Deoxyadenosines; Drug Interactions; Escherichia coli; Hydroxylamines; Mutagens | 1975 |
[Effect of adenine, adenosine and adenylic nucleotides on the mutagenic effect of hydroxylamine].
Topics: Adenine; Adenine Nucleotides; Adenosine; Drug Interactions; Escherichia coli; Hydroxylamines; Mutagens | 1975 |
Adenosine utilization in cordycepin-sensitive mutants of Saccharomyces cerevisiae.
Topics: Adenine; Adenosine; Biological Transport, Active; Deoxyadenosines; Mutation; Saccharomyces cerevisiae; Uracil | 1976 |
Enzymatic demodification of transfer RNA species containing N-6-(delta-2-isopentenyl)adenosine.
Topics: Adenine; Adenosine; Animals; Cattle; Chromatography, Paper; Isopentenyladenosine; Kinetics; Lactobacillus acidophilus; Liver; Mevalonic Acid; RNA, Bacterial; RNA, Transfer | 1975 |
G2+M arrest of cultured mammalian cells after incorporation of tritium-labeled nucleosides.
Topics: Adenine; Adenosine; Cell Division; Cell Line; DNA; Mitosis; Thymidine; Tritium; Uridine | 1977 |
Effect of thio reagents on platelet transport processes and responses to stimuli.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Biological Transport, Active; Blood Platelets; Collagen; Humans; In Vitro Techniques; Platelet Aggregation; Serotonin; Stimulation, Chemical; Sulfhydryl Reagents | 1977 |
Purine toxicity in human lymphoblasts.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Cell Division; Cell Line; Drug Synergism; Glucose; Hypoxanthines; Lymphocytes; Mutation; Phosphoribosyl Pyrophosphate; Purines; Ribonucleotides; Uridine | 1977 |
Adenine and adenosine metabolism in phytohemagglutinin (PHA) - stimulated and unstimulated normal human lymphocytes.
Topics: Adenine; Adenine Nucleotides; Adenine Phosphoribosyltransferase; Adenosine; Adenosine Deaminase; Humans; Hypoxanthines; Inosine; Lectins; Lymphocyte Activation; Lymphocytes | 1977 |
Adenine and adenosine metabolism in lymphocytes deficient in adenosine deaminase (ADA) activity.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase; Humans; Hypoxanthines; Immunologic Deficiency Syndromes; Inosine; Lymphocytes; Nucleoside Deaminases | 1977 |
Isolated rat liver cells - purine metabolism and effects of fructose.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Animals; Fructose; Guanine; Guanine Nucleotides; Hypoxanthines; Liver; Oxygen Consumption; Phosphates; Purines; Rats | 1977 |
6-Azauridine, an inhibitor of the purine salvage pathway.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Azauridine; DNA; HeLa Cells; Hypoxanthine Phosphoribosyltransferase; Kinetics; Pentosyltransferases; Purines | 1977 |
Electrophysiological evidence for chemosensitivity to adenosine, adenine and sugars in Spodoptera exempta and related species.
Topics: Adenine; Adenosine; Animals; Carbohydrates; Dose-Response Relationship, Drug; Lepidoptera; Moths; Plant Extracts; Sensory Receptor Cells; Species Specificity; Zea mays | 1977 |
Isolation of cytokinin binding protein from tobacco leaves by bioaffinity chromatography and its partial characterization.
Topics: Adenine; Adenosine; Amino Acids; Benzyl Compounds; Binding Sites; Binding, Competitive; Carrier Proteins; Chromatography, Affinity; Cytokinins; Kinetics; Molecular Weight; Nicotiana; Plant Growth Regulators; Plants; Plants, Toxic; Spectrophotometry, Ultraviolet | 1977 |
The function of adenosine deaminase in the human erythrocyte.
Topics: Adenine; Adenosine; Adenosine Deaminase; Erythrocytes; Humans; Immunologic Deficiency Syndromes; Kinetics; Nucleoside Deaminases | 1977 |
Adenosine deaminase and immunodeficiency: an in vitro model.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Humans; Immunologic Deficiency Syndromes; Lectins; Lymphocyte Activation; Nucleoside Deaminases | 1977 |
The control of cell proliferation by preformed purines: a genetic study. II. Pleiotropic manifestations and mechanism of a control exerted by adenylic purines on PRPP synthesis.
Topics: Adenine; Adenosine; Adenosine Kinase; Anti-Bacterial Agents; Azepines; Cell Line; Hypoxanthine Phosphoribosyltransferase; Mutation; Pentosephosphates; Phosphoribosyl Pyrophosphate; Ribonucleosides | 1977 |
Purine metabolism in isolated rat hepatocytes.
Topics: Adenine; Adenine Nucleotides; Adenosine; Allantoin; Animals; Guanine; Guanine Nucleotides; Hypoxanthines; Liver; Oxygen Consumption; Purines; Rats | 1977 |
Adenosine uptake by the isolated epithelium of guine pig jejunum.
Topics: Adenine; Adenosine; Animals; Biological Transport; Depression, Chemical; Diffusion; Epithelium; Female; Guanosine; Guinea Pigs; Hexobendine; Hypoxanthines; Inosine; Intestinal Absorption; Intestinal Mucosa; Jejunum; Kinetics; Male; Thionucleosides | 1977 |
Salvage of adenosine, inosine, hypoxanthine, and adenisine by the isolated epithelium of guinea pig jejunum.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Epithelium; Female; Guinea Pigs; Hypoxanthines; In Vitro Techniques; Inosine; Inosine Monophosphate; Intestinal Mucosa; Jejunum; Male; Purines | 1977 |
[Consequences of incorporation of adenosine on the turnover rate of the adenine nucleotides in the isolated perfused rabbit heart (author's transl)].
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Coronary Circulation; Heart; Heart Rate; Myocardium; Phosphocreatine; Rabbits | 1977 |
Studies on adenine and adenosine metabolism by intact human erythrocytes using high performance liquid chromatography.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Blood Glucose; Chromatography, High Pressure Liquid; Erythrocytes; Glycolysis; Humans; Inosine Nucleotides; Kinetics; Lactates; Purines | 1976 |
AMP analogs: their function in the activation of glycogen phosphorylase b.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Binding Sites; Binding, Competitive; Cysteine; Dialysis; Enzyme Activation; Glucosephosphates; In Vitro Techniques; Kinetics; Nucleotides; Phosphorylases; Protein Conformation; Spectrophotometry; Temperature; Thermodynamics | 1976 |
Transport and metabolism of adenosine in human blood platelets.
Topics: Adenine; Adenosine; Binding, Competitive; Biological Transport, Active; Blood Platelets; Cell Membrane; Humans; Kinetics; Ouabain; Papaverine; Phlorhizin; Sulfhydryl Reagents | 1976 |
Metabolic effects of ethyl adenosine 5'-carboxylate in Ehrlich ascites tumor cells in vitro.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Carboxylic Acids; Carcinoma, Ehrlich Tumor; Deoxyglucose; Nucleosides; Purine Nucleotides | 1976 |
Active transport of adenine and adenosine by blood platelets and cultured endothelial cells [proceedings].
Topics: Adenine; Adenosine; Biological Transport, Active; Blood Platelets; Endothelium; Humans; In Vitro Techniques | 1976 |
Fermentation of purines and their effect on the adenylate energy charge and viability of starved Peptococcus prévotii.
Topics: Acetates; Adenine; Adenosine; Adenosine Triphosphate; Ammonia; Anaerobiosis; Butyrates; Carbon Dioxide; Fermentation; Peptococcus; Purines; Ribose; RNA, Bacterial; Xanthines | 1976 |
Stimulation by adenine of uridine uptake in cultured mammalian cells.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Cells, Cultured; Guanosine; Rats; RNA; Uridine | 1976 |
[Interaction of adenine derivatives with chloroplast membranes].
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adsorption; Cell Membrane; Chloroplasts; Photophosphorylation | 1976 |
Endogenously released adenine derivatives: a possible role in epileptogenesis.
Topics: Adenine; Adenosine; Animals; Hypoxanthines; Inosine; Rats; Seizures | 1976 |
Ribonucleoprotein particles containing heterogeneous nuclear RNA in the cellular slime mold Dictyostelium discoideum.
Topics: Adenine; Adenine Nucleotides; Adenosine; Centrifugation, Density Gradient; Electrophoresis, Polyacrylamide Gel; Fungal Proteins; Myxomycetes; Nucleic Acid Hybridization; Nucleoproteins; Polynucleotides; Protein Binding; RNA; Transcription, Genetic; Tritium; Uracil | 1975 |
Possible relationship of poly(A) shortening to mRNA turnover.
Topics: Adenine; Adenine Nucleotides; Adenosine; Base Sequence; Dactinomycin; Emetine; Female; HeLa Cells; Humans; Molecular Weight; Polynucleotides; RNA, Messenger | 1975 |
Changes in RNA in relation to growth of the fibroblast. III. Posttranscriptional regulation of mRNA formation in resting and growing cells.
Topics: Adenine; Adenosine; Animals; Cell Division; Cell Fractionation; Cell Nucleus; Cells, Cultured; Cytoplasm; Deoxyadenosines; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Hypoxanthines; Kinetics; Mice; Nucleic Acid Hybridization; Phosphorus Radioisotopes; Poly U; Polynucleotides; RNA, Messenger; Tritium | 1975 |
Characterization of nucleoside transport in hymenolepidid cestodes.
Topics: Adenine; Adenosine; Animals; Binding, Competitive; Biological Transport, Active; Cestoda; Cricetinae; Deoxyadenosines; Guanosine; Hymenolepis; Hypoxanthines; Kinetics; Male; Mice; Nucleosides; Rats; Stimulation, Chemical; Thymidine; Thymine; Uracil; Uridine | 1975 |
Two approaches that increase the activity of analogs of adenine nucleosides in animal cells.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Animals; Carcinoma, Ehrlich Tumor; Deamination; Deoxyadenine Nucleotides; Deoxyadenosines; Dideoxynucleotides; DNA; Drug Synergism; L Cells; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Nucleoside Deaminases; Phosphates; Purine Nucleosides; RNA; Thymidine; Uridine; Vidarabine | 1975 |
Mechanism of action of ethanolamine ammonia-lyase, an adenosylcobalamin-dependent enzyme. Proton nuclear magnetic resonance studies of the binding of adenine nucleosides and substrate to ethanolamine ammonia-lyase.
Topics: Adenine; Adenosine; Ammonia-Lyases; Binding Sites; Clostridium; Deoxyadenosines; Ethanolamine Ammonia-Lyase; Ethanolamines; Kinetics; Magnetic Resonance Spectroscopy; Mathematics; Protein Binding; Protein Conformation; Vitamin B 12 | 1975 |
Uptake of adenosine 5'-monophosphate by Escherichia coli.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Carbon Radioisotopes; Escherichia coli; Micropore Filters; Models, Biological; Mutation; Nucleic Acids; Nucleotidases; Pentosyltransferases; Phosphorus Radioisotopes; Tritium | 1975 |
Comparison of tritiated hypoxanthine, adenine and adenosine for purine-salvage incorporation into nucleic acids of the malarial parasite, Plasmodium berghei.
Topics: Adenine; Adenosine; Allopurinol; Animals; Erythrocytes; Hypoxanthines; Inosine; Inosine Nucleotides; Mice; Nucleic Acids; Plasmodium berghei; Purines | 1975 |
3-Methyl-2-butenal: an enzymatic degradation product of the cytokinin, N-6-(delta-2 isopentenyl)adenine.
Topics: Adenine; Adenosine; Aldehydes; Chromatography, Gas; Chromatography, Thin Layer; Hydrolases; Mass Spectrometry; Plant Growth Regulators; Plants; Zea mays | 1975 |
A general method of purification of adenosine deaminase by affinity chromatography.
Topics: Adenine; Adenosine; Aminohydrolases; Animals; Cattle; Cellulose; Chickens; Chromatography, Affinity; Duodenum; Electrophoresis; Erythrocytes; Humans; Intestinal Mucosa; Spleen | 1975 |
Thin-layer chromatography of brain adenine nucleoside and nucleotides and determination of ATP specific activity.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Animals; Carbon Radioisotopes; Cerebral Cortex; Charcoal; Chromatography, Thin Layer; Luciferases; Methods; Rats | 1975 |
Pathways of nucleotide metabolism in Schistosoma mansoni--VI adenosine phosphorylase.
Topics: Adenine; Adenosine; Animals; Hypoxanthines; Kinetics; Phosphates; Phosphotransferases; Schistosoma mansoni; Time Factors; Transaminases | 1975 |
Independent blood-brain barrier transport systems for nucleic acid precursors.
Topics: Adenine; Adenosine; Animals; Biological Transport, Active; Blood-Brain Barrier; Brain; DNA; Guanosine; Hypoxanthines; Inosine; Kinetics; Purines; Pyrimidines; Rats; RNA; Uridine | 1975 |
Association of the polyadenylate segment of messenger RNA with other polynucleotide sequences in mouse sarcoma 180 polyribosomes.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Base Sequence; Chromatography, Affinity; Hypoxanthines; Mice; Polynucleotides; Polyribosomes; Ribonucleases; RNA, Messenger; RNA, Neoplasm; RNA, Ribosomal; Sarcoma 180; Uridine | 1975 |
A rapid and sensitive auxin binding system for detecting N6-substituted adenines, and some urea and thiourea derivatives, that show cytokinin activity in cell division tests.
Topics: Adenine; Adenosine; Amino Acids; Biological Assay; Biological Transport, Active; Cell Division; Cytokinins; Fungi; Glucose; Indoleacetic Acids; Methods; Plant Growth Regulators; Ribonucleosides; Thiourea; Urea | 1975 |
The pathway of adenylate catabolism in Azotobacter vinelandii. Evidence for adenosine monophosphate nucleosidase as the regulatory enzyme.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Aminohydrolases; Animals; Azotobacter; Cell-Free System; Hypoxanthines; Immunoglobulins; N-Glycosyl Hydrolases; Nucleoside Deaminases; Phosphates; Rabbits | 1975 |
The methylated constituents of L cell messenger RNA: evidence for an unusual cluster at the 5' terminus.
Topics: Adenine; Adenosine; Alkaline Phosphatase; Animals; Base Sequence; Chromatography, Ion Exchange; L Cells; Methionine; Methylation; Mice; Nucleotides; Nucleotidyltransferases; Oligonucleotides; Polyribosomes; RNA, Messenger; Uridine | 1975 |
Mouse neuroblastoma adenylate cyclase. Adenosine and adenosine analogues as potent effectors of adenylate cyclase activity.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Adenylyl Cyclases; Animals; Clone Cells; Cytidine; Guanine; Guanosine; Kinetics; Mice; Neuroblastoma; Phosphorus Radioisotopes; Prostaglandins E; Ribose; Theophylline; Tolazoline; Uridine; Yohimbine | 1975 |
[Adsorption chromatography of the nitrogenous bases of nucleic acids and their derivatives on sephadex G-10 columns].
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Azaguanine; Chromatography; Cytosine; Cytosine Nucleotides; Guanine; Hypoxanthines; Nucleic Acids; Nucleotides; Pyrimidine Nucleotides; Uracil; Xanthines | 1975 |
Reactivation of chick erythrocyte nuclei in BHK derived cells with multiple biochemical lesions.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Cell Fusion; Cell Line; Cell Nucleolus; Cell Nucleus; Deoxycytidine; DNA; Erythrocytes; Guanosine; Hybrid Cells; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; RNA; Thymidine; Uridine | 1975 |
Metabolic co-operation between biochemically variant hamster cells and heterokaryons formed between these cells and chick erythrocytes.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Cell Fusion; Cell Line; Cell Nucleus; Erythrocytes; Hybrid Cells; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine | 1975 |
Determination of labeled adenine by means of adsorption on cellulose nitrate filters: a sensitive method for estimation of nucleosidase activity.
Topics: Adenine; Adenosine; Adsorption; Cellulose; Chloroplasts; Filtration; Microchemistry; N-Glycosyl Hydrolases; Plants | 1975 |
Inhibition of mitogen mediated lymphocyte blastogenesis by adenosine.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Humans; Inosine; Lymphocyte Activation; Mitogens | 1975 |
Biosynthesis of formycin. Formation of formycin from formycin B.
Topics: Adenine; Adenosine; Amino Acids; Antibiotics, Antineoplastic; Aspartic Acid; Fluorides; Formycins; Fumarates; Guanine; Guanosine; Inosine Nucleotides; Ligases; Lyases; Streptomyces | 1975 |
Stacking interactions of nucleobases: NMR-investigations. II. Self-association of purine-and pyrimidine-derivatives.
Topics: Adenine; Adenosine; Caffeine; Chemical Phenomena; Chemistry; Cytosine; Deuterium; Hypoxanthines; Magnetic Resonance Spectroscopy; Polymers; Purines; Pyrimidines; Thermodynamics; Uracil; Uric Acid; Water | 1975 |
Association of sexual hormones with nucleobases in water: NMR-investigations.
Topics: Adenine; Adenosine; Caffeine; Chemical Phenomena; Chemistry; Cytosine; Deuterium; Estradiol; Hypoxanthines; Magnetic Resonance Spectroscopy; Purines; Pyrimidines; Testosterone; Thermodynamics; Uracil; Uric Acid; Water | 1975 |
Halo sugar nucleosides. 5. Synthesis of angustmycin A and some base analogues.
Topics: Adenine; Adenosine; Anti-Bacterial Agents; Catalysis; Cytosine; Isomerism; Methods; Nucleosides; Oxidation-Reduction | 1976 |
Relative importance of alternative pathways of purine nucleotide biosynthesis in Ehrlich ascites tumor cells in vivo.
Topics: Adenine; Adenosine; AMP Deaminase; Animals; Carcinoma, Ehrlich Tumor; Glycine; Guanine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Mice; Pentosyltransferases; Purine Nucleotides | 1976 |
Search for an adenine photoproduct in DNA.
Topics: Adenine; Adenosine; Calorimetry; Circular Dichroism; DNA; Luminescent Measurements; Nucleic Acid Conformation; Polydeoxyribonucleotides; Radiation Effects; Species Specificity; Spectrophotometry; Spectrophotometry, Ultraviolet; Temperature; Thermodynamics; Ultraviolet Rays | 1976 |
The postanoxic regeneration of 5'-adenosine nucleotides in rabbit kidney tissue during in vitro perfusion.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Female; Hypoxanthines; Hypoxia; Inosine; Kidney; Male; Organ Preservation; Perfusion; Purines; Rabbits; Regeneration; Ribose | 1976 |
The reactions of oxo-osmium ligand complexes with isopentenyl adenine and its nucleoside.
Topics: Adenine; Adenosine; Binding Sites; Ketones; Kinetics; Ligands; Magnetic Resonance Spectroscopy; Molecular Conformation; Osmium; Spectrophotometry; Spectrophotometry, Infrared; Thymidine | 1976 |
Effects of N6-endonorbornan-2-yl-9-methyladenine, N0861, on negative chronotropic and vasodilatory actions of adenosine in the canine heart in vivo.
Topics: Adenine; Adenosine; Animals; Coronary Vessels; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Injections, Intravenous; Male; Norbornanes; Purinergic Antagonists; Vasodilation | 1992 |
Identification of the guanine binding domain peptide of the GTP-binding site of glucagon.
Topics: Adenine; Adenine Nucleotides; Adenosine; Amino Acid Sequence; Binding Sites; Binding, Competitive; Chromatography, High Pressure Liquid; Chymotrypsin; Electrophoresis, Polyacrylamide Gel; Glucagon; Guanosine Triphosphate; Humans; Kinetics; Molecular Sequence Data; Peptide Fragments | 1992 |
Direct and indirect stimulations of cyclic AMP formation in human brain.
Topics: Adenine; Adenosine; Cerebral Cortex; Cyclic AMP; Female; Humans; In Vitro Techniques; Isoproterenol; Male; Norepinephrine; Prazosin; Pyrilamine; Species Specificity | 1992 |
Turnover of cyclic adenosine-5'-monophosphate is elevated in skeletal muscle of vitamin E-deficient rabbits.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cyclic AMP; Muscles; Rabbits; Vitamin E; Vitamin E Deficiency | 1992 |
Ionization of adenine derivatives: EPR and ENDOR studies of X-irradiated adenine.HCl.1/2H2O and adenosine.HCl.
Topics: Adenine; Adenosine; Electron Spin Resonance Spectroscopy; Free Radicals | 1992 |
Specificity and affinity of binding of phosphate-containing compounds to CheY protein.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Bacterial Proteins; Binding Sites; Guanosine Triphosphate; Kinetics; Magnetic Resonance Spectroscopy; Membrane Proteins; Methyl-Accepting Chemotaxis Proteins; Nucleotides; Phosphates; Phosphoric Monoester Hydrolases; Phosphorus; Phosphorylation; Protein Binding; Protons; Sensitivity and Specificity; Thymine Nucleotides; Uridine Triphosphate | 1992 |
Involvement of cyclic adenosine 3',5'-monophosphate in methylation during 1-methyladenine production by starfish ovarian follicle cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Animals; Concanavalin A; Cyclic AMP; Female; Methionine; Methionine Adenosyltransferase; Methylation; Ovarian Follicle; Starfish; Trypsin | 1992 |
Transient absorption spectra and quenching of coumarin excited states by nucleic acid bases.
Topics: Adenine; Adenosine; Coumarins; Deoxyadenosines; Kinetics; Lasers; Molecular Structure; Photolysis; Thymidine; Thymine | 1992 |
Inhibition of adenosine metabolism increases myocardial interstitial adenosine concentrations and coronary flow.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Coronary Circulation; Extracellular Space; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Myocardium; Perfusion; Tubercidin; Vascular Resistance | 1992 |
L1210/B23.1 cells express equilibrative, inhibitor-sensitive nucleoside transport activity and lack two parental nucleoside transport activities.
Topics: Adenine; Adenosine; Animals; Antiviral Agents; Biological Transport; Carrier Proteins; Cell Membrane; Clone Cells; Formycins; Kinetics; Leukemia L1210; Membrane Proteins; Mice; Mutagenesis; Nucleoside Transport Proteins; Nucleosides; Thioinosine; Thymidine; Tumor Cells, Cultured; Vidarabine | 1992 |
Evidence that adenosine receptors in the dog left atrium are not of the typical A1 or A2 adenosine receptor subtypes.
Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Dogs; Female; Heart Atria; In Vitro Techniques; Male; Myocardium; Norbornanes; Receptors, Purinergic; Theophylline; Vasodilation; Xanthines | 1992 |
A low-affinity nucleobase transporter in the protozoan parasite Giardia intestinalis.
Topics: Adenine; Adenosine; Animals; Binding, Competitive; Carrier Proteins; Giardia lamblia; Guanine; Kinetics; Membrane Proteins; Nucleoside Transport Proteins; Temperature; Thymine | 1992 |
N-0861 selectively antagonizes adenosine A1 receptors in vivo.
Topics: Adenine; Adenosine; Animals; Dose-Response Relationship, Drug; Heart Rate; Injections, Intravenous; Male; Norbornanes; Purinergic Antagonists; Rats; Rats, Inbred Strains; Theophylline; Vasodilation | 1992 |
Measurement of rat plasma adenosine levels during normoxia and hypoxia.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Animals; Blood Pressure; Carbon Dioxide; Chromatography, High Pressure Liquid; Dipyridamole; Edetic Acid; Egtazic Acid; Hydrogen-Ion Concentration; Hypoxia; Male; Oxygen; Phosphorylation; Rats; Rats, Inbred Strains | 1992 |
Analysis of the inhibition of commitment of murine erythroleukemia (MEL) cells to terminal maturation by N6-methyladenosine.
Topics: Adenine; Adenosine; Animals; Cell Differentiation; Cell Division; Cell Survival; Deoxyadenosines; Dimethyl Sulfoxide; Hemoglobins; Homocysteine; Leukemia, Erythroblastic, Acute; Methionine; Mice; RNA, Messenger; Structure-Activity Relationship; Tumor Cells, Cultured | 1992 |
Evaluation of N-0861, (+-)-N6-endonorbornan-2-yl-9-methyladenine, as an A1 subtype-selective adenosine receptor antagonist in the guinea pig isolated heart.
Topics: Adenine; Adenosine; Animals; Carrier Proteins; Coronary Vessels; Guinea Pigs; Heart; Heart Conduction System; Hypoxia; In Vitro Techniques; Membrane Proteins; Norbornanes; Nucleoside Transport Proteins; Perfusion; Receptors, Purinergic; Vasodilation | 1992 |
Glucose-induced modulation of nutrient influx in Schistosoma mansoni.
Topics: Adenine; Adenosine; Animals; Arginine; Biological Transport; Choline; Cytosine; Female; Glucose; Histidine; Lysine; Male; Schistosoma japonicum; Schistosoma mansoni | 1992 |
Transport and metabolism of D-[3H]adenosine and L-[3H]adenosine in rat cerebral cortical synaptoneurosomes.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Biological Transport; Cerebral Cortex; Neurons; Rats; Stereoisomerism; Synaptosomes; Tritium; Tubercidin | 1992 |
Synthesis and biological studies of unsaturated acyclonucleoside analogues of S-adenosyl-L-homocysteine hydrolase inhibitors.
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Animals; Anti-Bacterial Agents; Enzyme Inhibitors; Female; Hydrolases; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Structure-Activity Relationship; Tissue Distribution | 1992 |
Adenine deaminase and adenine utilization in Saccharomyces cerevisiae.
Topics: Adenine; Adenosine; Aminohydrolases; Cell Division; Cloning, Molecular; Culture Media; Escherichia coli; Gene Expression Regulation, Fungal; Genes, Bacterial; Mutation; Nitrogen; Proline; Quaternary Ammonium Compounds; Restriction Mapping; RNA, Messenger; Saccharomyces cerevisiae | 1992 |
HPLC determination of adenine compounds as fluorescent derivatives in canine red blood cells.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; Dogs; Erythrocytes; Sensitivity and Specificity | 1992 |
Purine salvage as a metabolite and energy saving mechanism in the ocular lens.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Cattle; Energy Metabolism; Epithelium; Inosine; Lens Capsule, Crystalline; Male; Oxidoreductases; Rats; Rats, Inbred Strains; Transferases | 1992 |
The precise radioimmunoassay of adenosine: minimization of sample collection artifacts and immunocrossreactivity.
Topics: Adenine; Adenosine; Artifacts; Automation; Chromatography, High Pressure Liquid; Cross Reactions; Humans; Immunosuppressive Agents; Molecular Structure; Radioimmunoassay; Sensitivity and Specificity; Temperature | 1992 |
Extracellular metabolism of adenine nucleotides and adenosine in the innervated skeletal muscle of the frog.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cations; Coformycin; Dipyridamole; In Vitro Techniques; Inosine Monophosphate; Kinetics; Muscles; Piperazines; Rana ridibunda; Sodium-Potassium-Exchanging ATPase; Thioinosine | 1991 |
Acyclic nucleotide analogues: synthesis, antiviral activity and inhibitory effects on some cellular and virus-encoded enzymes in vitro.
Topics: Adenine; Adenosine; Antiviral Agents; Cidofovir; Cytosine; DNA Viruses; Guanine; In Vitro Techniques; Nucleic Acid Synthesis Inhibitors; Nucleotides; Organophosphonates; Organophosphorus Compounds; Purine-Nucleoside Phosphorylase; Reverse Transcriptase Inhibitors; Ribonucleotide Reductases; Structure-Activity Relationship; Tubercidin | 1990 |
The role of 5'-methylthioadenosine on rat calvaria cell differentiation.
Topics: Adenine; Adenosine; Alkaline Phosphatase; Animals; Bone and Bones; Cell Differentiation; Cell Division; Cells, Cultured; Deoxyadenosines; Kinetics; Osteopontin; Purine-Nucleoside Phosphorylase; Rats; Sialoglycoproteins; Thionucleosides | 1992 |
Reduced S-adenosylhomocysteine hydrolase. Kinetics and thermodynamics for binding of 3'-ketoadenosine, adenosine, and adenine.
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Animals; Apoenzymes; Cattle; Hydrolases; Kinetics; Liver; Mathematics; Models, Theoretical; NAD; Protein Conformation; Spectrometry, Fluorescence; Spectrophotometry; Thermodynamics | 1992 |
Purine metabolites and pyrimidine bases in cerebrospinal fluid of children with simple febrile seizures.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Child, Preschool; Cytosine; Female; Guanine; Guanosine; Humans; Hypoxanthine; Hypoxanthines; Infant; Inosine; Inosine Monophosphate; Male; Purines; Pyrimidine Nucleosides; Seizures, Febrile; Thymine; Uracil; Uric Acid; Xanthine; Xanthines | 1991 |
An alternative pathway of adenylate and ATP synthesis.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Erythrocytes; Humans; Myocardium; Rats; Reference Values | 1991 |
Effect of adenosine on the membrane potential changes of human neutrophils triggered by the tripeptide F-Met-Leu-Phe.
Topics: Adenine; Adenosine; Adenosine Deaminase; Calcium; Cell Membrane; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Kinetics; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils | 1991 |
Adenine nucleotide degradation in cultured chick heart muscle cells.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Chick Embryo; Chromatography, High Pressure Liquid; Dipyridamole; Glycolysis; Inosine; Myocardium; Oxidative Phosphorylation; Phosphorylation; Thioinosine | 1991 |
5-Amino-4-imidazolecarboxamide riboside raises adenosine in perfused hypoxic rat heart.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Aminoimidazole Carboxamide; Animals; Cardiac Output; Coronary Circulation; Heart; Hypoxia; Inosine; Male; Myocardium; Perfusion; Rats; Rats, Inbred Strains; Ribonucleosides | 1991 |
Synthesis of purine bases having a di(hydroxymethyl)cyclopentenyl group by means of high-pressure reaction and their anti-HIV activity.
Topics: Adenine; Adenosine; Antiviral Agents; Dideoxynucleosides; HIV; Molecular Structure; Prospective Studies | 1991 |
Synthesis of methylenecyclobutyl- and cyclobutenyl adenine A, potent antiviral carbocyclic analogues of oxetanocin A.
Topics: Adenine; Adenosine; Antiviral Agents; Molecular Structure | 1991 |
Comparative inhibitory effects of nucleoside analogues on different clinical isolates of human cytomegalovirus in vitro.
Topics: Adenine; Adenosine; Antiviral Agents; Cell Line; Cidofovir; Cytidine; Cytomegalovirus; Cytosine; Ganciclovir; Guanosine; Humans; Nucleosides; Organophosphonates; Organophosphorus Compounds; Thymidine | 1991 |
Enhanced interstitial fluid adenosine attenuates myocardial stunning.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Coronary Disease; Dogs; Extracellular Space; Female; Hemodynamics; Male; Time Factors; Ventricular Function | 1991 |
Serum albumin stimulates the reactivation of bovine lens epithelial cells in primary culture.
Topics: Adenine; Adenosine; Animals; Cattle; Cell Adhesion; Cell Division; Cell Movement; Cells, Cultured; Crystallins; Epithelial Cells; Epithelium; Kinetics; Lens, Crystalline; Phosphates; Serum Albumin, Bovine | 1991 |
Inhibitors of membrane lipid metabolism enhance complement-mediated nucleated cell killing through distinct mechanisms.
Topics: 1-Acylglycerophosphocholine O-Acyltransferase; Acylation; Adenine; Adenosine; Adenosine Triphosphate; Animals; Carcinoma, Ehrlich Tumor; Complement C9; Complement Membrane Attack Complex; Complement System Proteins; Cytotoxicity, Immunologic; Flow Cytometry; Homocysteine; Immunosuppressive Agents; L-Lactate Dehydrogenase; Membrane Lipids; Methylation; Mice; Thimerosal | 1991 |
Disturbance in the metabolism of 5'-methylthioadenosine and adenine in patients with neoplastic diseases, and in those with a deficiency in adenine phosphoribosyltransferase.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Adult; Aged; Deoxyadenosines; Female; Humans; Leukemia; Male; Middle Aged; Neoplasms; Osmolar Concentration; Thionucleosides | 1991 |
Role of presynaptic purinoceptors and cyclic AMP on the noradrenaline release in cat cerebral arteries.
Topics: Adenine; Adenosine; Animals; Cats; Cerebral Arteries; Cyclic AMP; Dipyridamole; Electric Stimulation; Female; Male; Norepinephrine; Potassium; Receptors, Purinergic | 1990 |
Tyrosine 65 is photolabeled by 8-azidoadenine and 8-azidoadenosine at the NAD binding site of diphtheria toxin.
Topics: Adenine; Adenosine; Amino Acid Sequence; Azides; Binding Sites; Binding, Competitive; Diphtheria Toxin; Models, Molecular; Molecular Sequence Data; Molecular Weight; NAD; Peptide Fragments; Tyrosine | 1991 |
Adenosine deaminase inhibitors: synthesis and structure-activity relationships of imidazole analogues of erythro-9-(2-hydroxy-3-nonyl)adenine.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Aminoimidazole Carboxamide; Animals; Binding Sites; Cattle; Chemical Phenomena; Chemistry; Intestines; Molecular Structure; Structure-Activity Relationship; Tubercidin | 1991 |
Methotrexate inhibits neutrophil function by stimulating adenosine release from connective tissue cells.
Topics: Adenine; Adenosine; Analysis of Variance; Cell Line; Cells, Cultured; Connective Tissue; Endothelium, Vascular; Fibroblasts; Humans; In Vitro Techniques; Kinetics; Methotrexate; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Umbilical Veins | 1991 |
Evidence for the presence of P2-purinoceptors at the surface of human articular chondrocytes in monolayer culture.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Cartilage, Articular; Cells, Cultured; Humans; Indomethacin; Nucleotides; Pertussis Toxin; Prostaglandins E; Receptors, Purinergic; Theophylline; Virulence Factors, Bordetella | 1991 |
[Investigations of the influence of essential oils and their main components on the adenosine uptake by cultivated endothelial cells].
Topics: Adenine; Adenosine; Animals; Cattle; Cells, Cultured; Endothelium, Vascular; Nasal Mucosa; Oils, Volatile; Olfactory Nerve | 1991 |
Chromatographic behaviour of cyclodextrin complexes of nucleotides, nucleosides and their bases.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Chromatography, Liquid; Cyclodextrins; Nucleosides; Nucleotides; Thymidine; Thymine; Uracil; Uridine | 1990 |
Role of AMP on the activation of glycogen synthase and phosphorylase by adenosine, fructose, and glutamine in rat hepatocytes.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Enzyme Activation; Fructose; Glutamine; Glycogen Synthase; Kinetics; Liver; Male; Models, Biological; Phosphorylase a; Phosphorylases; Rats; Rats, Inbred Strains | 1990 |
Methylthioadenosine serves as a single carbon source to the folate co-enzyme pool in rat bone marrow cells.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Bone Marrow; Carbon; Deoxyadenosines; Folic Acid; Formates; Glycine; Guanine; Male; Methionine; Methionine Adenosyltransferase; Oxidation-Reduction; Rats; Rats, Inbred Strains; Serine; Thionucleosides | 1990 |
Purine derivatives as competitive inhibitors of human erythrocyte membrane phosphatidylinositol 4-kinase.
Topics: 1-Phosphatidylinositol 4-Kinase; Adenine; Adenosine; Adenosine Triphosphate; Binding, Competitive; Chemical Phenomena; Chemistry; Erythrocyte Membrane; Humans; Molecular Structure; Phosphotransferases; Purines; Structure-Activity Relationship | 1990 |
Effects of glucose and adenosine on the ATP content of hamster spermatids.
Topics: Adenine; Adenosine; Adenosine Kinase; Adenosine Triphosphate; Animals; Cricetinae; Cyclic AMP; Dipyridamole; Dose-Response Relationship, Drug; Fructose; Galactose; Glucose; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Male; Mannose; Spermatids; Tubercidin | 1990 |
Purine levels and metabolism in human follicular fluid.
Topics: Adenine; Adenosine; Adult; Chorionic Gonadotropin; Chromatography, High Pressure Liquid; Cyclic AMP; Female; Follicular Fluid; Humans; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; Menotropins; Oocytes; Ovary; Purines | 1990 |
Direct injection of blood samples into a high-performance liquid chromatographic adenine analyser to measure adenine, adenosine, and the adenine nucleotides with fluorescence detection.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; Cricetinae; Cyclic AMP; Fluorescence; Humans; Injections; Rats | 1990 |
Species-dependent effects of adenosine on heart rate and atrioventricular nodal conduction. Mechanism and physiological implications.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Atrioventricular Node; Bundle of His; Depression, Chemical; Dipyridamole; Female; Guinea Pigs; Heart Atria; Heart Block; Heart Rate; Hypoxia; Male; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Xanthines | 1990 |
7-Deaza-2-phenyladenines: structure-activity relationships of potent A1 selective adenosine receptor antagonists.
Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Adipose Tissue; Animals; Binding, Competitive; Brain; Chemical Phenomena; Chemistry, Physical; Corpus Striatum; Hypoxanthines; In Vitro Techniques; Phenylisopropyladenosine; Rats; Receptors, Purinergic; Structure-Activity Relationship | 1990 |
A new method of sampling blood for measurement of plasma adenosine.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Blood Specimen Collection; Carbon Radioisotopes; Catheterization; Dipyridamole; Humans | 1990 |
Adenosine metabolism in kidney slices under normoxic conditions.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Animals; Biological Transport; Chromatography, High Pressure Liquid; Female; Guinea Pigs; In Vitro Techniques; Inosine; Kidney; Oxygen; Pentostatin; Purines | 1990 |
Adenosine as adjunct to potassium cardioplegia: effect on function, energy metabolism, and electrophysiology.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Drug Combinations; Electrophysiology; Energy Metabolism; Heart; Heart Arrest, Induced; Potassium; Potassium Compounds; Rats | 1990 |
Endogenous adenosine restrains renin release in conscious rats.
Topics: Adenine; Adenosine; Adenosine Deaminase; Animals; Hydralazine; Hypertension, Renovascular; Male; Rats; Rats, Inbred Strains; Renin; Xanthines | 1990 |
Purine nucleotide metabolism in resident and activated rat macrophages in vitro.
Topics: Adenine; Adenosine; Animals; Cells, Cultured; Guanine; Guanosine; Hypoxanthine; Hypoxanthines; Inosine; Macrophage Activation; Macrophages; Pentosephosphates; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Rats; Thioglycolates | 1985 |
Studies on the mechanism of immunosuppression with adenine.
Topics: Adenine; Adenosine; Animals; Chromatography, High Pressure Liquid; Erythrocytes; Female; Hemolytic Plaque Technique; Hypoxanthine Phosphoribosyltransferase; Immunosuppressive Agents; Kidney; Mice; Mice, Inbred C57BL; Phosphoribosyl Pyrophosphate; Sheep; Spleen | 1985 |
cAMP-dependent protein kinase and lipolysis in rat adipocytes. I. Cell preparation, manipulation, and predictability in behavior.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Adenosine Deaminase; Adipose Tissue; Animals; Isoproterenol; Kinetics; Lipolysis; Male; Phenylisopropyladenosine; Protein Kinases; Rats; Rats, Inbred Strains; Seasons; Starvation | 1985 |
Studies on the receptor mediating cyclic AMP-independent enhancement by adenosine of IgE-dependent mediator release from rat mast cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenine Nucleotides; Adenosine; Animals; Cyclic AMP; Dose-Response Relationship, Drug; Immunoglobulin E; In Vitro Techniques; Male; Mast Cells; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Serotonin; Tachyphylaxis; Theophylline; Time Factors; Tubercidin | 1986 |
A1 and A2 adenosine receptors regulate adenylate cyclase in cultured human lung fibroblasts.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Cell Line; Cyclic AMP; Fibroblasts; Humans; Lung; Receptors, Cell Surface; Receptors, Purinergic; Theophylline; Virulence Factors, Bordetella | 1986 |
Potentiation by levamisole, methisoprinol, and adenine or adenosine of the inhibitory activity of human interferon against encephalomyocarditis virus.
Topics: Adenine; Adenosine; Drug Synergism; Encephalomyocarditis virus; HeLa Cells; Humans; Inosine; Inosine Pranobex; Interferons; Levamisole; Virus Replication | 1986 |
Effect of some drugs on thromboplastin activity in mouse trophoblast cells in vitro and in vivo.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Animals; Calcium Channel Blockers; Dinoprostone; Felodipine; Female; Gallic Acid; Methylation; Mice; Monensin; Nifedipine; Nitrendipine; Pregnancy; Prostaglandins E; Thromboplastin; Trophoblasts; Tubercidin; Verapamil | 1986 |
Cyclic nucleotide potentiation of muscarinic responses in neuroblastoma cells.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Acetylcholine; Adenine; Adenosine; Animals; Bucladesine; Cell Line; Cyclic AMP; Cyclic GMP; Dopamine; Membrane Potentials; Neurons; Receptors, Muscarinic | 1987 |
Antigiardial activity of guanine arabinoside. Mechanism studies.
Topics: Adenine; Adenosine; Animals; Arabinonucleotides; Deoxyadenosines; Deoxyguanosine; DNA Replication; Giardia; Guanine; Guanosine; Guanosine Triphosphate; Protein Biosynthesis; RNA | 1987 |
Effects of alkylxanthines and calcium antagonists on adenosine uptake by cultured rabbit coronary microvascular endothelium.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcium Channel Blockers; Cells, Cultured; Coronary Vessels; Dipyridamole; Endothelium; Ethanol; Isoproterenol; Male; Microcirculation; Rabbits; Theophylline; Trifluoperazine; Xanthines | 1987 |
Salvage mechanisms for regeneration of adenosine triphosphate in rat cardiac myocytes.
Topics: Adenine; Adenosine; Adenosine Kinase; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Female; Kinetics; Myocardium; Phosphoribosyl Pyrophosphate; Rats; Rats, Inbred Strains | 1987 |
Susceptibility of human immunodeficiency virus type 1 replication in vitro to acyclic adenosine analogs and synergy of the analogs with 3'-azido-3'-deoxythymidine.
Topics: Adenine; Adenosine; Animals; Antiviral Agents; Dideoxynucleotides; Drug Synergism; HIV-1; Organophosphonates; Reverse Transcriptase Inhibitors; T-Lymphocytes; Thymine Nucleotides; Virus Replication; Zidovudine | 1989 |
[Role of hypothalamic adenosinergic systems in regulating states of wakefulness in the rat].
Topics: Adenine; Adenosine; Animals; Hypothalamus; Hypothalamus, Posterior; Immunosuppressive Agents; Male; Piperazines; Rats; Rats, Inbred Strains; Sleep; Wakefulness | 1989 |
Negative-ion mass spectrometry of substituted adenine bases and adenosine nucleosides.
Topics: Adenine; Adenosine; Mass Spectrometry | 1989 |
Histidine 21 is at the NAD+ binding site of diphtheria toxin.
Topics: Adenine; Adenosine; Binding Sites; Diethyl Pyrocarbonate; Diphtheria Toxin; Formates; Histidine; Kinetics; NAD; Niacinamide; Peptide Fragments | 1989 |
Imbalance of purine nucleotides in alanosine-resistant baby hamster kidney cells.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Kinase; Adenylosuccinate Lyase; Adenylosuccinate Synthase; Alanine; Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Cricetinae; Culture Media; Humans; Hypoxanthine Phosphoribosyltransferase; Mutation; Phosphotransferases; Purines; Selection, Genetic; Transformation, Genetic; Uridine | 1989 |
Turnover of adenosine in plasma of human and dog blood.
Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosylhomocysteinase; Animals; Blood Flow Velocity; Dipyridamole; Dogs; Forearm; Half-Life; Humans; Hydrolases; Nucleotidases; Tritium | 1989 |
Correlation between the antiviral activity of acyclic and carbocyclic adenosine analogues in murine L929 cells and their inhibitory effect on L929 cells S-adenosylhomocysteine hydrolase.
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Animals; Antiviral Agents; Cell Line; Fibroblasts; Hydrolases; Kinetics; Mice; Vaccinia virus; Vesicular stomatitis Indiana virus; Virus Replication | 1989 |
[The pool of free purine and pyrimidine nucleosides and bases in the thymocytes, and splenic T- and B-lymphocytes of C3HA mice during the growth of solid hepatoma 22a].
Topics: Adenine; Adenosine; Animals; B-Lymphocytes; Deoxycytidine; DNA, Neoplasm; Guanine; Hypoxanthine; Hypoxanthines; Inosine; Liver Neoplasms, Experimental; Mice; Mice, Inbred C3H; Purine Nucleosides; Pyrimidine Nucleosides; Spleen; T-Lymphocytes; Thymus Gland; Time Factors; Xanthine; Xanthines | 1989 |
Transendothelial transport and metabolism of adenosine and inosine in the intact rat aorta.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aorta; Endothelium, Vascular; Female; Inosine; Male; Muscle, Smooth, Vascular; Purines; Rats; Rats, Inbred Strains; Tritium | 1989 |
Some pharmacological activities of novel adenine-related compounds isolated from a marine sponge Agelas mauritiana.
Topics: Adenine; Adenosine; Animals; Aorta; Cell Cycle; Erythrocytes; In Vitro Techniques; Kinetics; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Mice; Muscle Relaxation; Muscle, Smooth, Vascular; Naphthols; Porifera; Rabbits; Rats; Rats, Inbred Strains; Receptors, Purinergic | 1989 |
Cytotoxicity of N6-cycloalkylated adenine and adenosine analogs to mouse hepatoma cells.
Topics: Adenine; Adenosine; Alkylating Agents; Animals; Antineoplastic Agents; Cell Transformation, Neoplastic; Liver Neoplasms, Experimental; Mice; Tumor Cells, Cultured | 1989 |
Inhibitors of adenosine catabolism improve recovery of dog myocardium after ischemia.
Topics: Adenine; Adenosine; Animals; Dipyridamole; Dogs; Drug Combinations; Energy Metabolism; Female; Free Radicals; Male; Myocardial Contraction; Myocardial Reperfusion Injury | 1989 |
Changes in the nucleotide metabolism of Ehrlich ascites tumour cells during their growth in vivo.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Carcinoma, Ehrlich Tumor; Cell Division; Chromatography, High Pressure Liquid; Female; Hypoxanthines; Mice; Mice, Inbred ICR; Microscopy, Electron; Mitochondria; Purine Nucleotides; Pyrimidine Nucleotides; Time Factors; Tumor Cells, Cultured | 1989 |
Contribution of S-adenosylhomocysteine to cardiac adenosine formation.
Topics: Adenine; Adenosine; Animals; Guinea Pigs; Heart; Homocysteine; In Vitro Techniques; Kinetics; Models, Theoretical; Myocardium; Perfusion; S-Adenosylhomocysteine | 1989 |
Mechanism of adenosine triphosphate catabolism induced by deoxyadenosine and by nucleoside analogues in adenosine deaminase-inhibited human erythrocytes.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Coformycin; Deoxyadenosines; Erythrocytes; Humans; In Vitro Techniques; Kinetics; Nucleoside Deaminases; Pentostatin; Ribonucleosides; Structure-Activity Relationship | 1989 |
Adenosine deaminase and adenosine uptake inhibitions facilitate ventilation in rats.
Topics: Adenine; Adenosine; Adenosine Deaminase; Animals; Carotid Arteries; Carotid Body; Chemoreceptor Cells; Dipyridamole; Injections; Nucleoside Deaminases; Rats; Rats, Inbred Strains; Respiration; Stimulation, Chemical; Xanthines | 1989 |
Functional evidence for the presence of adenosine A2-receptors in cultured coronary endothelial cells.
Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cells, Cultured; Coronary Vessels; Cyclic AMP; Endothelium; Guinea Pigs; In Vitro Techniques; Muscle, Smooth, Vascular; Receptors, Purinergic; Xanthines | 1987 |
Analyses of adenosine and adenine nucleotides in biological materials by fluorescence reaction-high-performance liquid chromatography.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Erythrocyte Membrane; Humans; Mice; Neuroblastoma; Ouabain; Rats; Sodium-Potassium-Exchanging ATPase; Spectrometry, Fluorescence | 1987 |
Characterization of adenosine receptors in bone. Studies on the effect of adenosine analogues on cyclic AMP formation and bone resorption in cultured mouse calvaria.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Bone and Bones; Bone Resorption; Cells, Cultured; Colforsin; Cyclic AMP; Mice; Phenylisopropyladenosine; Pyrrolidinones; Receptors, Cyclic AMP; Rolipram; Theophylline | 1987 |
Novel acyclic adenosine analogs inhibit Epstein-Barr virus replication.
Topics: Adenine; Adenosine; Antimetabolites; Antiviral Agents; Cell Line; Cell Survival; DNA, Viral; Herpesvirus 4, Human; Organophosphonates; Organophosphorus Compounds; Virus Replication | 1987 |
Inhibition of phosphoinositide metabolism in human polymorphonuclear leukocytes by S-adenosylhomocysteine.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Homocysteine; Humans; In Vitro Techniques; Kinetics; Neutrophils; Phosphatidylinositols; S-Adenosylhomocysteine; Type C Phospholipases | 1988 |
Absolute rates of adenosine formation during ischaemia in rat and pigeon hearts.
Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Deaminase; Adenosine Kinase; Adult; AMP Deaminase; Animals; Columbidae; Coronary Disease; Female; Heart; Histocytochemistry; Humans; Male; Middle Aged; Myocardium; Nucleotidases; Nucleotides; Phosphoric Monoester Hydrolases; Rats; Rats, Inbred Strains; Species Specificity; Tubercidin | 1988 |
Purine salvage in Entamoeba histolytica.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Chromatography, High Pressure Liquid; Entamoeba histolytica; Guanine; Guanine Nucleotides; Guanosine; Inosine Monophosphate; Kinetics; Ribose | 1985 |
Accumulation of adenosine 3',5'-monophosphate in slices of rat cerebral cortex induced by alpha-adrenergic agonists. II. Studies on mechanisms underlying the interaction with adenosine.
Topics: Adenine; Adenosine; Adrenergic alpha-Agonists; Animals; Calcimycin; Calcium; Cerebral Cortex; Cyclic AMP; Drug Interactions; Norepinephrine; Rats; Rats, Inbred Strains | 1987 |
Detection and characterization of a nucleoside transport system in human fibroblast lysosomes.
Topics: Adenine; Adenosine; Amino Acid Transport Systems; Biological Transport; Carrier Proteins; Cell Line; Dipyridamole; Fibroblasts; Humans; Kinetics; Lysosomes; Nucleosides; Substrate Specificity; Thioinosine | 1989 |
Regulation of macrophage lysosomal secretion by adenosine, adenosine phosphate esters, and related structural analogues of adenosine.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Esterases; Homocysteine; Kinetics; Lysosomes; Macrophages; Male; Mice; Receptors, Cell Surface; Receptors, Purinergic; Secretory Rate; Structure-Activity Relationship; Theophylline; Tubercidin | 1985 |
Antiviral potency of adenosine analogues: correlation with inhibition of S-adenosylhomocysteine hydrolase.
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Antibiotics, Antineoplastic; Antiviral Agents; Hydrolases; Kinetics; Measles virus; Reoviridae; Tubercidin; Vaccinia virus; Vesicular stomatitis Indiana virus; Virus Replication | 1985 |
Influence of cyclic AMP and hydrolysis products on cell type regulation in Dictyostelium discoideum.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Acid Phosphatase; Adenine; Adenosine; Caffeine; Cell Differentiation; Cyclic AMP; Dictyostelium; Electrophoresis, Polyacrylamide Gel; Hydrolysis; Isoenzymes; Spores, Fungal | 1985 |
Adenosine receptor-mediated changes in cyclic AMP production and DNA synthesis in cultured arterial smooth muscle cells.
Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; DNA Replication; Muscle, Smooth, Vascular; Phenylisopropyladenosine; Platelet-Derived Growth Factor; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic | 1985 |
Adenosine inhibits prolactin and growth hormone secretion in a clonal pituitary cell line.
Topics: Adenine; Adenosine; Adenosine Deaminase; Animals; Carbachol; Cell Line; Chromatography, High Pressure Liquid; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; Dipyridamole; Growth Hormone; Phenylisopropyladenosine; Pituitary Gland; Pituitary Neoplasms; Prolactin; Rats; Thyrotropin-Releasing Hormone; Vasoactive Intestinal Peptide | 1985 |
Adenosine is unimportant in controlling coronary blood flow in unstressed dog hearts.
Topics: Adenine; Adenosine; Adenosine Deaminase; Animals; Coronary Circulation; Dogs; Female; Hemodynamics; Histamine; Lymph; Male; Mathematics; Receptors, Cell Surface; Receptors, Purinergic; Regional Blood Flow; Substrate Specificity; Vasodilation | 1985 |
Role of adenosine deaminase in human monocyte differentiation and tumor cell cytotoxicity.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Antibody-Dependent Cell Cytotoxicity; Carcinoma, Transitional Cell; Cell Differentiation; Cell Line; Cytotoxicity, Immunologic; Homocysteine; Humans; Lymphokines; Macrophage Activation; Monocytes; Nucleoside Deaminases; Phagocytosis; Superoxides; Urinary Bladder Neoplasms | 1985 |
Comparative efficacy of broad-spectrum antiviral agents as inhibitors of rotavirus replication in vitro.
Topics: Adenine; Adenosine; Amides; Antiviral Agents; Cell Line; Cytidine; Dose-Response Relationship, Drug; Pyrazoles; Ribavirin; Ribonucleosides; Ribose; Rotavirus; Tubercidin; Vidarabine; Virus Replication | 1986 |
Possible involvement of the Ni-protein in the prejunctional inhibitory effect of a stable adenosine analogue (R-PIA) on noradrenaline release in the rat hippocampus.
Topics: Adenine; Adenosine; Animals; Colforsin; Cyclic AMP; GTP-Binding Proteins; Hippocampus; Male; Norepinephrine; Phenylisopropyladenosine; Rats; Rats, Inbred Strains | 1986 |
Differences in Ca2+ entry blockers revealed by effects on adenosine- and adrenergic- receptors and cyclic AMP levels of [2-3H]adenine-prelabeled vesicles prepared from guinea pig brain.
Topics: Adenine; Adenosine; Animals; Arrhythmias, Cardiac; Brain Chemistry; Calcium Channel Blockers; Cell Membrane; Cyclic AMP; Epinephrine; Guinea Pigs; In Vitro Techniques; Nifedipine; Perhexiline; Prenylamine; Receptors, Adrenergic; Receptors, Cell Surface; Receptors, Purinergic; Stereoisomerism; Tritium; Verapamil | 1986 |
Calcium entry blocking activity of dilazep in dog coronary artery.
Topics: Adenine; Adenosine; Adenosine Deaminase; Animals; Arteries; Azepines; Calcium; Calcium Channel Blockers; Coronary Vessels; Dilazep; Diltiazem; Dipyridamole; Dogs; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Lidoflazine; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1986 |
Cyclic AMP inhibits developmental regulation of Chlamydia trachomatis.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenine; Adenine Nucleotides; Adenosine; Antigens, Bacterial; Bucladesine; Chlamydia trachomatis; Cyclic AMP; HeLa Cells; Humans; Receptors, Cyclic AMP | 1986 |
The influence of inhibitors of the ATP degradative pathway on recovery of function and high energy phosphate after transient ischemia in the rat heart.
Topics: 5'-Nucleotidase; Acute Disease; Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Adenylate Kinase; Animals; Coronary Circulation; Coronary Disease; Dinucleoside Phosphates; Male; Nucleotidases; Rats; Rats, Inbred Strains; Thioinosine | 1986 |
Base liberation from nucleotides by superoxide and intramolecular enhancement effect of phosphate group.
Topics: Adenine; Adenosine; DNA; Free Radicals; Kinetics; Nucleosides; Nucleotides; Phosphates; Purines; Pyrimidines; Superoxides | 1987 |
Defective transport of pyrazolopyrimidine ribosides in insensitive Trypanosoma cruzi wild strains is a parasite-stage specific and reversible characteristic.
Topics: Adenine; Adenosine; Adenosine Kinase; Animals; Antiprotozoal Agents; Biological Transport; Drug Resistance; Formycins; Kinetics; Phosphotransferases; Pyrimidine Nucleosides; Trypanosoma cruzi | 1987 |
Adenosine accumulation in Saccharomyces cerevisiae cultured in medium containing low levels of adenine.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Monophosphate; Aspergillus; Chromatography, High Pressure Liquid; Hypoxanthine; Hypoxanthines; Inosine; Models, Chemical; Purine-Nucleoside Phosphorylase; Saccharomyces cerevisiae | 1986 |
Adenosine analog metabolism in Giardia lamblia. Implications for chemotherapy.
Topics: Adenine; Adenosine; Formycins; Giardia; Giardiasis; Guanine; Phosphorylation; Purine-Nucleoside Phosphorylase; Tubercidin | 1986 |
Synthesis of purines in human lymphoblast cells deficient in methylthioadenosine phosphorylase activity.
Topics: Adenine; Adenosine; B-Lymphocytes; Cell Line; Deoxyadenosines; Humans; Kinetics; Leukemia, Lymphoid; Lymphocytes; Pentosyltransferases; Purine-Nucleoside Phosphorylase; Purines; T-Lymphocytes; Thionucleosides | 1987 |
Improved maintenance of adenosine triphosphate in five-day perfused kidneys with adenine and ribose.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Animals; Dogs; Kidney; Perfusion; Potassium; Ribose; Sodium; Tissue Preservation | 1987 |
Trypanosoma cruzi adenine nucleoside phosphorylase. Purification and substrate specificity.
Topics: Adenine; Adenosine; Animals; Deoxyadenosines; Kinetics; Molecular Weight; Pentosyltransferases; Purine-Nucleoside Phosphorylase; Substrate Specificity; Thionucleosides; Trypanosoma cruzi | 1987 |
Comparison of the effects of adenine-ribose with adenosine for maintenance of ATP concentrations in 5-day hypothermically perfused dog kidneys.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Cold Temperature; Dogs; Kidney Cortex; Perfusion; Ribose; Time Factors; Water-Electrolyte Balance | 1988 |
7-Deaza-9-phenyladenines. A new class of adenosine receptor antagonists.
Topics: Adenine; Adenosine; Animals; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Rats; Receptors, Purinergic; Structure-Activity Relationship | 1988 |
Ruthenium(III) ion complexes with nucleic acid bases and nucleosides.
Topics: Adenine; Adenosine; Cytosine; Guanine; Guanosine; Inosine; Ruthenium; Ruthenium Compounds; Spectrophotometry; Spectrophotometry, Infrared | 1988 |
Phosphorolytic cleavage of 2-fluoroadenine from 9-beta-D-arabinofuranosyl-2-fluoroadenine by Escherichia coli. A pathway for 2-fluoro-ATP production.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Binding, Competitive; Cell Line; Escherichia coli; Humans; Kidney; Kinetics; Leukemia; Liver; Mice; Phosphates; Purine Nucleosides; Rats; Vidarabine | 1987 |
Adenosine handling in interstitia of cremaster muscle studied by bioassay.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arterioles; Biological Assay; Cricetinae; Diffusion; Dipyridamole; Extracellular Space; Kinetics; Methods; Muscles; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Thioinosine; Vasodilation | 1988 |
9-(trans-2',trans-3'-dihydroxycyclopent-4'-enyl) derivatives of adenine and 3-deazaadenine: potent inhibitors of bovine liver S-adenosylhomocysteine hydrolase.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosylhomocysteinase; Animals; Cattle; Hydrolases; Kinetics; Liver; NAD | 1988 |
SVLM21, a mutant of Sindbis virus able to grow in Aedes albopictus cells in the absence of methionine, shows increased sensitivity to S-adenosylhomocysteine hydrolase inhibitors such as neplanocin A.
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Aedes; Animals; Antiviral Agents; Cell Line; Genes, Viral; Hydrolases; Methionine; Methyltransferases; Mutation; S-Adenosylmethionine; Sindbis Virus; Tubercidin; Viral Plaque Assay | 1988 |
Inhibition of methyltransferase reduces the turnover of acetylcholine receptors.
Topics: Adenine; Adenosine; Animals; Dose-Response Relationship, Drug; Endocytosis; Homocysteine; In Vitro Techniques; Methionine; Methyltransferases; Muscles; Myasthenia Gravis; Phospholipids; Rats; Receptors, Nicotinic | 1988 |
Implication of protein carboxymethylation in retinal pigment epithelial cell chemotaxis.
Topics: Adenine; Adenosine; Chemotaxis; Eye Proteins; Fibronectins; Homocysteine; Humans; Hydrolysis; Methanol; Pigment Epithelium of Eye; Platelet-Derived Growth Factor; Protein Methyltransferases; Protein O-Methyltransferase | 1988 |
Potential inhibitors of S-adenosylmethionine-dependent methyltransferases. 11. Molecular dissections of neplanocin A as potential inhibitors of S-adenosylhomocysteine hydrolase.
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Animals; Antibiotics, Antineoplastic; Antiviral Agents; Cattle; Cell Line; Chemical Phenomena; Chemistry; Hydrolases; Liver; Mice; Vaccinia virus; Virus Replication | 1988 |
Inhibition of T cell cytotoxicity by cyclosporine (CSA), adenosine (Ado) and an inhibitor of adenosine deaminase (ADA).
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Animals; Cyclosporins; Cytotoxicity, Immunologic; Drug Synergism; In Vitro Techniques; Male; Mice; T-Lymphocytes, Cytotoxic | 1986 |
Pathways of adenine nucleotide catabolism in human erythrocytes.
Topics: Adenine; Adenine Nucleotides; Adenosine; Blood Glucose; Coformycin; Erythrocytes; Humans; Hydrogen-Ion Concentration; Hypoxanthine; Hypoxanthines; Pentostatin; Phosphates; Tubercidin | 1986 |
A new synthetic pathway to adenine-2-d, 9-alkyladenine-2-d, adenosine-2-d, and 2'-deoxyadenosine-2-d.
Topics: Adenine; Adenosine; Deoxyadenosines; Deuterium; Indicators and Reagents; Isotope Labeling | 1986 |
Enhancement of biotinidase activity in mouse serum by inhibitors of methylation.
Topics: Adenine; Adenosine; Amidohydrolases; Animals; Biotinidase; Coformycin; Ethionine; Female; Liver; Methylation; Mice; Pentostatin; Vidarabine | 1987 |
Measurement of plasma adenosine concentration: methodological and physiological considerations.
Topics: Adenine; Adenosine; Dipyridamole; Erythrocytes; False Positive Reactions; Hemolysis; Humans; Indicators and Reagents; Radioisotope Dilution Technique; Tritium | 1987 |
Effects of adenosine and theophylline on canine tracheal smooth muscle tone.
Topics: Adenine; Adenosine; Animals; Dipyridamole; Dogs; Drug Interactions; In Vitro Techniques; Inosine; Male; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Theophylline; Trachea | 1987 |
Transient increase in release of adenosine during rapid cardiac pacing; transient effects on overdrive suppression of ventricular automaticity.
Topics: Adenine; Adenosine; Animals; Cardiac Pacing, Artificial; Electrocardiography; Heart Rate; Heart Ventricles; In Vitro Techniques; Male; Myocardium; Oxygen Consumption; Rats; Rats, Inbred Strains; Theophylline | 1987 |
Adenosine in cerebral homeostatic role: appraisal through actions of homocysteine, colchicine, and dipyridamole.
Topics: Adenine; Adenosine; Animals; Cerebral Cortex; Colchicine; Dipyridamole; Glutamates; Guinea Pigs; Homeostasis; Homocysteine; Hypoxia; Potassium; Rats | 1986 |
Adenosine export from the liver: oxygen dependency.
Topics: Adenine; Adenosine; Animals; Bicarbonates; Blood Substitutes; Chromatography, High Pressure Liquid; Fluorocarbons; Hypoxanthine; Hypoxanthines; Liver; Male; Oxygen; Perfusion; Purines; Rats; Rats, Inbred Strains | 1986 |
Incorporation of adenosine and adenine into hypoxanthine nucleotides of fresh red blood cells.
Topics: Adenine; Adenosine; Carbon Radioisotopes; Erythrocytes; Humans; In Vitro Techniques; Inosine Monophosphate; Inosine Nucleotides; Inosine Triphosphate | 1986 |
Disposition of homocysteine in rat hepatocytes and in nontransformed and malignant mouse embryo fibroblasts following exposure to inhibitors of S-adenosylhomocysteine catabolism.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Adenosylhomocysteinase; Animals; Cell Line; Cell Transformation, Neoplastic; Fibroblasts; Homocysteine; Hydrolases; In Vitro Techniques; Liver; Methionine; Rats; S-Adenosylhomocysteine | 1986 |
Purine metabolism in human neuroblastoma cell lines.
Topics: Adenine; Adenosine; Cell Line; Guanosine; Humans; Hypoxanthine; Hypoxanthines; Neuroblastoma; Nucleosides; Purine Nucleosides; Purine Nucleotides; Purines; Tubercidin | 1986 |
Purine salvage in rat heart myoblasts.
Topics: Adenine; Adenosine; Animals; Biological Transport; Hypoxanthine; Hypoxanthines; Inosine; Myocardium; Phosphates; Purine Nucleotides; Purines; Rats | 1986 |
Repair of etheno DNA adducts by N-glycosylases.
Topics: Acetaldehyde; Adenine; Adenosine; DNA Glycosylases; DNA Repair; Guanine; Guanosine; N-Glycosyl Hydrolases; Substrate Specificity | 1986 |
Chemical modification of adenine and cytosine residues with chloroacetaldehyde at the nucleoside and the tRNA level: the structural effect of chloroacetaldehyde modification.
Topics: Acetaldehyde; Adenine; Adenosine; Chemical Phenomena; Chemistry; Cytidine; Cytosine; Molecular Conformation; RNA, Transfer | 1986 |
Release of endogenous and radioactive purines from the rabbit retina.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Animals; Dipyridamole; Evoked Potentials; Female; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Male; Potassium; Purines; Rabbits; Retina; Tritium | 1986 |
Synthesis and biological properties of 9-(trans-4-hydroxy-2-buten-1-yl)adenine and guanine: open-chain analogues of neplanocin A.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Antibiotics, Antineoplastic; Guanine; Indicators and Reagents; Leukemia L1210; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1987 |
Urinary purines and nucleosides in immune deficiencies.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adult; Child; Deoxyadenosines; Female; Humans; Immunologic Deficiency Syndromes; Inosine; Purine Nucleosides; Purines; Pyrimidine Nucleosides; Pyrimidines; S-Adenosylhomocysteine; Thionucleosides | 1985 |
Inhibition of macrophage phagocytosis by methylation inhibitors. Lack of correlation of protein carboxymethylation and phospholipid methylation with phagocytosis.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Cells, Cultured; Deoxyadenosines; Homocysteine; Kinetics; Macrophages; Methylation; Mice; Phagocytosis; Phospholipids; Proteins; Vidarabine | 1985 |
Antagonism of the positive chronotropic effect of norepinephrine by purine nucleosides in rat atria.
Topics: Adenine; Adenosine; Animals; Deoxyadenosines; Heart Atria; Heart Rate; Inosine; Male; Norepinephrine; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Stimulation, Chemical | 1985 |
Inhibition of antibody production by 2-chloroadenosine.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Antibody Formation; B-Lymphocytes; Cells, Cultured; DNA Replication; Homocysteine; Immunosuppressive Agents; Lymphocyte Activation; Male; Methylation; Mice; S-Adenosylmethionine | 1985 |
Effects of adenosine deaminase inhibitors on lymphocyte-mediated cytolysis.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Cell Line; Coformycin; Cytotoxicity, Immunologic; Immunity, Cellular; Immunosuppressive Agents; Leukemia; Mice; Nucleoside Deaminases; Pentostatin; T-Lymphocytes, Cytotoxic | 1985 |
An experimental evaluation of nucleotide enhancement techniques for kidney transplantation.
Topics: Adenine; Adenosine; Animals; Dipyridamole; Dogs; Female; Graft Survival; Kidney; Kidney Transplantation; Nucleotides; Organ Preservation; Transplantation, Autologous | 1985 |
An analysis of multiple mechanisms of adenosine toxicity in baby hamster kidney cells.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Cell Adhesion; Cell Line; Coformycin; Drug Resistance; Drug Synergism; Guinea Pigs; Homocysteine; Kidney; Nucleotides; Pentostatin; Ribonucleotide Reductases; S-Adenosylhomocysteine; Uridine | 1985 |
Adenosine deaminase impairment and ribonucleotide reductase in human cells.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Cell Division; Deoxyadenosines; HeLa Cells; Humans; Interphase; Nucleoside Deaminases; Ribonucleotide Reductases; Thymine Nucleotides | 1985 |
Inhibition of adenosine deaminase from several sources by deaza derivatives of adenosine and EHNA.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Antiviral Agents; Erythrocytes; Escherichia coli; Humans; Kinetics; Nucleoside Deaminases; Saccharomyces cerevisiae; Structure-Activity Relationship | 1985 |
Hydrogen-bonding preferences in 2,6-diaminopurine: uracil (thymine) and 8-methyl adenine:uracil (thymine) complexes.
Topics: Adenine; Adenosine; Hydrogen Bonding; Nucleic Acid Conformation; Structure-Activity Relationship; Thymine; Uracil | 1986 |
Purine nucleotide synthesis in adrenal chromaffin cells.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Adenosine Deaminase; Adenosine Kinase; Adrenal Glands; Animals; Cattle; Chromaffin System; Formates; Glycine; Hypoxanthine Phosphoribosyltransferase; Male; Purine Nucleotides | 1985 |
Adenosine deaminase inhibition and myocardial adenosine metabolism during ischemia.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Monophosphate; Animals; Coronary Circulation; Coronary Disease; Inosine Monophosphate; Male; Myocardial Contraction; Myocardium; Nucleoside Deaminases; Purines; Rats; Rats, Inbred Strains | 1985 |
Adenosine nucleotides, adenosine and adenine as angiogenesis factors.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Angiogenesis Inducing Agents; Animals; Aorta; Cells, Cultured; Chemotaxis; Endothelium; Growth Substances; Swine | 1985 |
2-Chloroadenosine, a permeant for the nucleoside transporter.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Biological Transport; Blood Proteins; Carrier Proteins; Erythrocyte Membrane; Erythrocytes; Humans; Kinetics; Membrane Proteins; Nucleoside Transport Proteins; Thioinosine; Uridine | 1985 |
Effect of adenosine deaminase inhibitors on myocardial reactive hyperaemia following brief coronary occlusions.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Arterial Occlusive Diseases; Azaguanine; Blood Flow Velocity; Coronary Vessels; Dogs; Heart; Hyperemia; Nucleoside Deaminases | 1985 |
An early effect of the S component of staphylococcal leukocidin on methylation of phospholipid in various leukocytes.
Topics: Adenine; Adenosine; Animals; Cell Survival; Enzyme Activation; Homocysteine; Leukocidins; Membrane Lipids; Methylation; Neutrophils; Phospholipases A; Phospholipases A2; Phospholipids; Rabbits; Staphylococcus | 1985 |
Adenosine deaminase inhibition and myocardial purine release during normoxia and ischaemia.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Monophosphate; Animals; Coronary Circulation; Deamination; Depression, Chemical; Heart; Male; Myocardium; Nucleoside Deaminases; Oxygen Consumption; Perfusion; Purines; Rats; Rats, Inbred Strains | 1985 |
In vivo and in vitro age-related alterations in adenine nucleotide metabolism in human red cells.
Topics: Adenine; Adenine Nucleotides; Adenosine; Blood Preservation; Erythrocyte Aging; Erythrocytes; Humans | 1985 |
3H-uridine incorporation as a T lymphocyte indicator in the rat.
Topics: Adenine; Adenosine; Animals; Ascitic Fluid; Autoradiography; Cycloheximide; Cytidine; Dactinomycin; Female; Lymphocyte Depletion; Lymphopenia; Male; Orotic Acid; Phosphorus Isotopes; Polyethylenes; Puromycin; Rats; Rats, Inbred Strains; T-Lymphocytes; Thoracic Duct; Tritium; Uridine | 1973 |
Q-band chromosome patterns of a variant of the BHK-21 C13 cell line.
Topics: Adenine; Adenosine; Animals; Aza Compounds; Cell Line; Cell Transformation, Neoplastic; Chromosomes; Cricetinae; Drug Resistance; Karyotyping; Kidney; Microscopy, Fluorescence; Polyomavirus; Quinacrine; Staining and Labeling | 1973 |
[Incorporation of adenosine and adenine in isolated rabbit heart].
Topics: Adenine; Adenosine; Adenosine Monophosphate; Animals; Carbon Radioisotopes; Chromatography, Ion Exchange; Chromatography, Paper; Guanine Nucleotides; In Vitro Techniques; Kinetics; Myocardium; Perfusion; Rabbits; Spectrophotometry, Ultraviolet; Time Factors; Tritium | 1974 |
Species responsible for the fluorescence of 1:N6-ethenoadenosine.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Cyclic AMP; Dimethylformamide; Dioxins; Fluorescence; Heterocyclic Compounds; Hydrogen-Ion Concentration; Imidazoles; Magnetic Resonance Spectroscopy; Polycyclic Compounds; Protons; Solvents; Spectrometry, Fluorescence; Time Factors; Water | 1974 |
Regulation of the adenosine cyclic 3',5'-monophosphate content of rat cerebral cortex: ontogenetic development of the responsiveness to catecholamines and adenosine.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Cyclases; Adrenergic alpha-Antagonists; Aging; Animals; Animals, Newborn; Carbon Radioisotopes; Catecholamines; Cerebral Cortex; Cyclic AMP; Drug Synergism; Female; In Vitro Techniques; Isoproterenol; Male; Norepinephrine; Phentolamine; Pregnancy; Propranolol; Rats; Receptors, Adrenergic | 1973 |
Adenine nucleotide metabolism of blood platelets. 8. Transport of adenine into human platelets.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Antimetabolites; Antimycin A; Biological Transport, Active; Blood Platelets; Cyclic N-Oxides; Edetic Acid; Electrophoresis, Paper; Erythrocytes; Glucose; Humans; Hydrogen-Ion Concentration; Hypoxanthines; Kinetics; Papaverine; Prostaglandins; Time Factors; Tritium | 1973 |
Repression of alkaline phosphatase synthesis by adenine, adenosine and adenine nucleotides in an adenine auxotroph of Bacillus anthracis.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Alkaline Phosphatase; Bacillus anthracis; Caffeine; Chlorpromazine; Culture Media; Dinitrophenols; Enzyme Repression; Inosine Nucleotides; Lyases; Mutation; Phosphates; Theophylline | 1973 |
Mechanism of inhibition of bacterial growth by adenine.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Bacterial Proteins; Carbon Radioisotopes; Culture Media; Depression, Chemical; DNA, Bacterial; Edetic Acid; Escherichia coli; Guanosine; Inosine; Orotic Acid; Oxygen Consumption; Phosphorus Radioisotopes; Purine Nucleotides; Pyrimidine Nucleotides; RNA, Bacterial; Uridine | 1974 |
[Fluorescence of polyadenylic acid at ambiant temperature].
Topics: Adenine; Adenosine; Adenosine Monophosphate; Buffers; Hydrogen-Ion Concentration; Methods; Polynucleotides; Solvents; Spectrometry, Fluorescence; Temperature | 1973 |
Possible role of adenosine deaminase in suboptimal growth of the bacillus anthracis adenine auxotroph mutant.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Aminohydrolases; Bacillus anthracis; Carbon Radioisotopes; Cell-Free System; Culture Media; Deoxyadenosines; Hypoxanthines; Inosine; Lyases; Mutation; Pentosyltransferases; Phosphates; Succinates; Virulence | 1973 |
Primary platelet aggregation. Energy metabolism and the effect of inhibitors.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Antimetabolites; Blood Platelets; Chloromercuribenzoates; Colchicine; Cyanides; Edetic Acid; Epinephrine; Humans; Hydrochloric Acid; Hydrogen-Ion Concentration; Inosine Nucleotides; Lidocaine; Mercury; Organometallic Compounds; Platelet Adhesiveness; Platelet Aggregation; Prostaglandins; Serotonin; Sulfonic Acids; Time Factors; Tosyl Compounds; Tritium; Vasopressins | 1974 |
Correlation of growth inhibition patterns to nucleoside transport models in Neurospora crassa.
Topics: Adenine; Adenosine; Guanosine; Inosine; Ligases; Models, Biological; Neurospora; Neurospora crassa; Nucleosides; Pyrimidines; Succinates; Time Factors; Uridine | 1973 |
The regulation of purine utilization in bacteria. I. Purification of adenine phosphoribosyltransferase from Escherichia coli K12 and control of activity by nucleotides.
Topics: Acetone; Adenine; Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Ammonium Sulfate; Calcium Phosphates; Carbon Isotopes; Chemical Precipitation; Chlorides; Chromatography, Gel; Chromatography, Thin Layer; Culture Media; Deoxyadenosines; Electrophoresis; Enzyme Activation; Escherichia coli; Gels; Hydrogen-Ion Concentration; Kinetics; Magnesium; Manganese; Molecular Weight; Nucleotides; Pentosephosphates; Pentosyltransferases; Phosphoric Acids; Ribose; Streptomycin; Sulfuric Acids | 1971 |
Gold (III) complexes of adenine nucleotides.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Buffers; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography; Chromatography, Gel; Chromatography, Thin Layer; Cyclic AMP; Deoxyadenosines; Ethanol; Gold; Hydrogen-Ion Concentration; Mathematics; Models, Structural; Phosphoric Acids; Polymers; Potassium; Solubility; Spectrophotometry; Thallium; Time Factors; Ultracentrifugation; Ultraviolet Rays | 1971 |
Adenyl cyclase activity in cultivated human skin fibroblasts.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenylyl Cyclases; Adrenocorticotropic Hormone; Carbon Isotopes; Cells, Cultured; Chromatography, Paper; Cyclic AMP; Enzyme Activation; Epinephrine; Fibroblasts; Fluorides; Glucagon; Humans; Isoproterenol; Norepinephrine; Skin; Sodium; Tritium; Vasopressins | 1971 |
Formation and metabolism of cyclic AMP in the mammalian central nervous system.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Animals; Biogenic Amines; Brain; Cerebellum; Cerebral Cortex; Cyclic AMP; Electric Stimulation; Guinea Pigs; Histamine; In Vitro Techniques; Magnesium; Mice; Norepinephrine; Potassium; Rabbits; Rats; Theophylline | 1971 |
Regulation and mechanism of phosphoribosylpyrophosphate synthetase: repression by end products.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Aspartic Acid; Cell-Free System; Culture Media; Enzyme Repression; Fluorometry; Histidine; Nucleotides; Oxidoreductases; Phosphates; Phosphoric Monoester Hydrolases; Phosphorus Isotopes; Phosphotransferases; Salmonella typhimurium; Transferases; Tryptophan; Uridine | 1971 |
Factors influencing the accumulation of cyclic AMP in brain tissue.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Brain; Cerebellum; Cerebral Cortex; Cyclic AMP; Diphenhydramine; Dogs; Electric Stimulation; Guinea Pigs; Histamine; In Vitro Techniques; Magnesium; Mice; Norepinephrine; Osmolar Concentration; Phosphorus Isotopes; Potassium; Potassium Chloride; Rats; Serotonin; Theophylline; Tissue Extracts; Tritium | 1970 |
Effect of membrane depolarization and biogenic amines on the formation of cyclic AMP in incubated brain slices.
Topics: Acetylcholine; Adenine; Adenosine; Adenosine Triphosphate; Alkaloids; Animals; Biogenic Amines; Calcium; Carbon Isotopes; Caudate Nucleus; Cerebellum; Cerebral Cortex; Cevanes; Chromatography, Thin Layer; Cyclic AMP; Dopamine; Guinea Pigs; Histamine; In Vitro Techniques; Membrane Potentials; Norepinephrine; Ouabain; Phenethylamines; Potassium; Rabbits; Serotonin; Stimulation, Chemical; Tetrodotoxin; Toxins, Biological; Veratrine | 1970 |
Cyclic AMP-stimulated protein kinase prepared from bovine thyroid glands.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Caseins; Cattle; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Cobalt; Cyclic AMP; Cyclic GMP; Cytosine Nucleotides; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Guanine Nucleotides; Guanosine; Histones; Hydrogen-Ion Concentration; In Vitro Techniques; Isoleucine; Magnesium; Manganese; Nucleotides; Phosphorus Isotopes; Phosphotransferases; Protamines; Proteins; Serum Albumin, Bovine; Thyroid Gland; Uracil Nucleotides | 1972 |
Inhibition of the protein kinase by adenine compounds: competitive inhibition with respect to ATP.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Ammonium Sulfate; Animals; Chemical Precipitation; Chromatography, DEAE-Cellulose; Cyclic AMP; Enzyme Activation; Histones; Kinetics; Liver; Male; Phosphorus Isotopes; Phosphotransferases; Proteins; Rats | 1972 |
Selective binding of barbital to the adenine moieties of FAD and NAD.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Barbiturates; Chemical Phenomena; Chemistry; Deuterium; Dimethyl Sulfoxide; Flavin-Adenine Dinucleotide; Fluorometry; Infrared Rays; Magnetic Resonance Spectroscopy; Methylation; Models, Chemical; NAD; Optical Rotatory Dispersion; Phenobarbital; Spectrophotometry; Ultraviolet Rays | 1970 |
Significance of the caffeine-like effect of various purines, pyrimidines and derivatives on adipose-tissue phosphodiesterase.
Topics: Adenine; Adenosine; Adipose Tissue; Animals; Caffeine; Deoxyadenosines; Epididymis; Guanosine; Male; Phosphoric Monoester Hydrolases; Purines; Pyrimidines; Rats | 1971 |
Periodate oxidations of enamines. I. Oxidation of adenosine 5'-monophosphate in the presence of methylamine.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Amines; Amino Sugars; Base Sequence; Carbon Dioxide; Chemical Phenomena; Chemistry; Chromatography, Paper; Deoxyuridine; Formates; Kinetics; Methylamines; Models, Chemical; Oxidation-Reduction; Periodic Acid; Phosphates; RNA; Structure-Activity Relationship; Uracil Nucleotides | 1971 |
Phenylalanyl transfer ribonucleic acid synthetase from Escherichia coli. Analysis of the adenosine triphosphate binding site.
Topics: Acylation; Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Alcohols; Amino Acyl-tRNA Synthetases; Binding Sites; Cyclohexanes; Deoxyadenosines; Diphosphates; Escherichia coli; Organophosphonates; Phosphoric Acids; Phosphorus Isotopes; Protein Binding; Purines; Structure-Activity Relationship; Thermodynamics | 1971 |
Fluorometric determination of adenine and its derivatives by reaction with glyoxal hydrate trimer.
Topics: Acetates; Adenine; Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Aldehydes; Fluorometry; Indicators and Reagents; Kinetics; Methods; Microchemistry; NAD; Spectrometry, Fluorescence | 1972 |
The regulation of purine utilization in bacteria. IV. Roles of membrane-localized and pericytoplasmic enzymes in the mechanism of purine nucleoside transport across isolated Escherichia coli membranes.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Biological Transport; Carbon Isotopes; Cell Membrane; Escherichia coli; Glucose; Guanine Nucleotides; Guanosine Triphosphate; Hypoxanthines; Inosine; Kinetics; Nucleosides; Pentosephosphates; Pentosyltransferases; Phosphoric Acids; Ribose; Temperature | 1972 |
Inactivation of yeast alcohol dehydrogenase by dehydroascorbic acid and D-arabinosone.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Alcohol Oxidoreductases; Arabinose; Ascorbic Acid; Chloromercuribenzoates; Depression, Chemical; Glutathione; Ketones; Mercaptoethanol; NAD; Niacinamide; Ozone; Saccharomyces | 1972 |
Inhibition of adenosine deaminase by alcohols derived from adenine nucleosides.
Topics: Adenine; Adenosine; Alcohols; Aminohydrolases; Animals; Binding Sites; Borohydrides; Cattle; Chemical Phenomena; Chemistry; Ethers; Glycols; Intestines; Nucleosides; Oxidation-Reduction; Periodic Acid; Structure-Activity Relationship | 1972 |
Studies in prebiotic synthesis. VI. Synthesis of purine nucleosides.
Topics: Adenine; Adenosine; Chemical Phenomena; Chemistry; Chromatography, Paper; Diphosphates; Electrophoresis, Paper; Guanine; Guanosine; Hot Temperature; Hypoxanthines; Inosine; Kinetics; Magnesium; Nucleosides; Phosphates; Ribonucleosides; Ribose | 1972 |
[Determination of adenine, adenosine, adenosine-5'-monophosphoric acid, thymine and thymidine by gel filtration].
Topics: Adenine; Adenosine; Chromatography; Chromatography, Gel; Cyclic AMP; Spectrophotometry; Thymidine; Thymine | 1972 |
Acid phosphatases from Fusarium moniliforme. II. Further studies on substrate specificity and mode of action of acid phosphatase II.
Topics: Acid Phosphatase; Adenine; Adenosine; Cytidine; Diphosphates; Fusarium; Glucosephosphates; Glycerophosphates; Guanosine; Hydrogen-Ion Concentration; Kinetics; Nitrophenols; Phosphates; Phosphoenolpyruvate; Uridine | 1972 |
The cytostatic action of extracellular NAD in tumour-bearing mice.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Carcinoma, Ehrlich Tumor; Cell Division; Culture Techniques; Cyclic AMP; DNA; Female; HeLa Cells; L-Lactate Dehydrogenase; Mast-Cell Sarcoma; Mice; NAD; Neoplasms, Experimental; Thymidine; Tritium | 1972 |
The control of platelet responsiveness by agents that influence cyclic AMP metabolism.
Topics: Adenine; Adenosine; Carbon Isotopes; Catecholamines; Cyclic AMP; Ethylmaleimide; Platelet Adhesiveness; Prostaglandins | 1972 |
Cyclic 3',5'-adenosine monophosphate in human blood platelets. IV. Regulatory role of cyclic amp in platelet function.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Blood Platelets; Butyrates; Carbon Isotopes; Chromatography, Paper; Cyclic AMP; Humans; Platelet Adhesiveness; Prostaglandins; Protein Binding; Tritium | 1972 |
Cyclic adenosine 3',5'-monophosphate in guinea pig cerebral cortical slices. I. Formation of cyclic adenosine 3',5'-monophosphate from endogenous adenosine triphosphate and from radioactive adenosine triphosphate formed during a prior incubation with radi
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Animals; Carbon Isotopes; Cerebral Cortex; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cyclic AMP; Diffusion; Drug Synergism; Guinea Pigs; Half-Life; Histamine; In Vitro Techniques; Kinetics; Male; Norepinephrine; Sorbitol; Time Factors; Tritium; Veratrine | 1973 |
On the active site topography of isoleucyl transfer ribonucleic acid synthetase of Escherichia coli B.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Amino Acids; Amino Acyl-tRNA Synthetases; Binding Sites; Binding, Competitive; Carbon Isotopes; Catalysis; Chemical Phenomena; Chemistry; Diphosphates; Escherichia coli; Isoleucine; Kinetics; Magnesium; Mathematics; Naphthalenes; Phosphorus Isotopes; Ribose; Spectrometry, Fluorescence; Structure-Activity Relationship; Sulfonic Acids; Toluidines | 1973 |
The cyclic AMP system of human brain.
Topics: Adenine; Adenosine; Adenylyl Cyclases; Adult; Aged; Brain; Brain Chemistry; Brain Neoplasms; Carbon Isotopes; Cerebral Cortex; Child, Preschool; Cyclic AMP; Epinephrine; Female; Histamine; Humans; Intracranial Aneurysm; Isoproterenol; Male; Middle Aged; Norepinephrine; Phosphoric Diester Hydrolases; Serotonin; Tritium; Veratrine | 1973 |
The interaction of -cyclodextrin with nucleic acid monomer units.
Topics: Adenine; Adenosine; Chemical Phenomena; Chemistry; Circular Dichroism; Cyclic AMP; Mathematics; Nucleic Acids; Polysaccharides; Temperature; Thermodynamics | 1973 |
Actions of various cyclic nucleotides, nucleosides and purine bases on the synthesis of corticosterone in vitro.
Topics: Adenine; Adenosine; Adrenal Glands; Adrenocorticotropic Hormone; Allopurinol; Animals; Corticosterone; Cyclic AMP; Cyclic GMP; Drug Synergism; Hypoxanthines; In Vitro Techniques; Inosine; Inosine Nucleotides; Male; Nucleosides; Nucleotides; Purines; Rats; Uracil Nucleotides; Xanthines | 1972 |
An ATP pool associated with adenyl cyclase of brain tissue.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Brain; Carbon Isotopes; Chromatography, Thin Layer; Cyclic AMP; Electrophoresis, Paper; Guinea Pigs; Histamine; In Vitro Techniques; Male; Time Factors; Tritium; Veratrine | 1973 |
Microbiological assay of purines.
Topics: Adenine; Adenosine; Escherichia coli; Genetics, Microbial; Hydrolysis; Hypoxanthines; Kinetics; Methods; Mutation; Periodic Acid; Purines; Tritium; Uracil | 1973 |
Accumulation of adenosine 3', 5'-monophosphate in incubated slices from discrete regions of squirrel monkey cerebral cortex: effect of norepinephrine, serotonin and adenosine.
Topics: Adenine; Adenosine; Animals; Auditory Cortex; Carbon Isotopes; Cerebral Cortex; Cyclic AMP; Drug Synergism; Gyrus Cinguli; Haplorhini; Histamine; In Vitro Techniques; Male; Norepinephrine; Serotonin; Visual Cortex | 1973 |
Specificity of adenosine on transmitter output at the neuromuscular junction.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Animals; Calcium; Cyclic AMP; Cystine; Diaphragm; Evoked Potentials; Guanosine; In Vitro Techniques; Inosine; Magnesium; Membrane Potentials; Muscle Contraction; Neuromuscular Junction; Rats; Uridine | 1973 |
Studies on the antilipolytic effect of adenosine and related compounds in isolated fat cells.
Topics: Adenine; Adenosine; Adipose Tissue; Animals; Culture Techniques; Cyclic AMP; Dipyridamole; Dose-Response Relationship, Drug; Drug Synergism; Glycerol; Hypoxanthines; Inosine; Insulin; Male; Norepinephrine; Rats; Theophylline; Xanthines | 1973 |
High affinity uptake of cyclic AMP in rat brain slices.
Topics: Adenine; Adenosine; Animals; Brain; Cerebellum; Cerebral Cortex; Corpus Striatum; Cyclic AMP; Deoxyadenosines; Hypothalamus; In Vitro Techniques; Medulla Oblongata; Mesencephalon; Rats | 1973 |
Subcellular localization of (14C)adenine derivatives newly-formed in cerebral tissues and the effects of electrical excitation.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Animals; Brain; Carbon Radioisotopes; Cell Nucleus; Centrifugation, Density Gradient; Cyclic AMP; Cytosol; Electric Stimulation; Guinea Pigs; Hypoxanthines; In Vitro Techniques; Inosine; Microsomes; Mitochondria; Synaptic Transmission; Synaptosomes; Tritium | 1973 |
Myocardial nucleotide synthesis from purine bases and nucleosides. Comparison of the rates of formation of purine nucleotides from various precursors and identification of the enzymatic routes for nucleotide formation in the isolated rat heart.
Topics: Adenine; Adenosine; Animals; Carbon Radioisotopes; Enzyme Precursors; Hypoxanthines; In Vitro Techniques; Inosine; Methods; Myocardium; Oxidative Phosphorylation; Phosphotransferases; Purine Nucleotides; Rats; Tritium | 1973 |
Cyclic 3',5'-adenosine monophosphate in isolated bone cells. II. Responses to adenosine and parathyroid hormone.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Bone and Bones; Carbon Radioisotopes; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Epinephrine; Fluorides; Guanosine; In Vitro Techniques; Parathyroid Hormone; Rats; Theophylline; Uridine | 1974 |
Antagonism of morphine analgesia by adenine, adenosine, and adenine nucleotides.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Analgesics; Animals; Cyclic AMP; Cytidine; Deoxyadenosines; Hypoxanthines; Male; Methods; Mice; Morphine; Structure-Activity Relationship; Uridine | 1973 |
Specificity of nucleotide-induced insulin secretion.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cricetinae; Cyclic AMP; Cytosine Nucleotides; Glucose; Guanosine Triphosphate; Inosine Nucleotides; Insulin; Insulin Secretion; Male; Pancreas; Phosphates; Phosphocreatine; Sodium; Uracil Nucleotides; Uridine | 1974 |
The effect of adenosine analogues on the ATP-pyrophosphate exchange reaction catalysed by methionyl-tRNA synthetase.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Amino Acyl-tRNA Synthetases; Binding Sites; Chromatography, Paper; Diphosphates; Electrophoresis, Paper; Escherichia coli; Kinetics; Methionine; Phosphorus Radioisotopes; Protein Binding; Purines; Ribose; Structure-Activity Relationship | 1974 |
Depolarization-evoked accumulation of cyclic AMP in brain slices: inhibition by exogenous adenosine deaminase.
Topics: Adenine; Adenosine; Aminohydrolases; Animals; Carbon Radioisotopes; Cerebral Cortex; Cyclic AMP; Electric Stimulation; Guinea Pigs; Histamine; In Vitro Techniques; Norepinephrine; Ouabain; Potassium; Theophylline; Veratrine | 1973 |
The effects of bases and nucleosides on the intracellular contents of nucleotides and 5-phosphoribosyl 1-pyrophosphate in Escherichia coli.
Topics: Adenine; Adenine Nucleotides; Adenosine; Carbon Radioisotopes; Cytosine Nucleotides; Escherichia coli; Guanine; Guanine Nucleotides; Guanosine; Hypoxanthines; Inosine; Inosine Nucleotides; Kinetics; Organophosphorus Compounds; Orotic Acid; Pentosephosphates; Phosphoric Acids; Ribonucleosides; Ribonucleotides; Time Factors; Uracil; Uracil Nucleotides; Uridine | 1974 |
Adenosine-mediated elevation of cyclic 3':5'-adenosine monophosphate concentrations in cultured mouse neuroblastoma cells.
Topics: Acetylcholine; Adenine; Adenosine; Animals; Benzyl Compounds; Clone Cells; Cyclic AMP; Ethers; Guanine; Guanosine; Histamine; Imidazoles; Isoproterenol; Mice; Neuroblastoma; Phosphodiesterase Inhibitors; Stimulation, Chemical; Theophylline | 1973 |
Metabolism and transport of purine nucleosides by membrane preparations of Micrococcus sodonensis.
Topics: Adenine; Adenine Nucleotides; Adenosine; Aminohydrolases; Biological Transport, Active; Carbon Radioisotopes; Hydrogen-Ion Concentration; Inosine; Magnesium; Membranes; Micrococcus; Microscopy, Electron; Organophosphorus Compounds; Pentosephosphates; Pentosyltransferases; Phosphoric Acids; Spheroplasts | 1974 |
Effects of carcinogens and other agents on histone methylation by a histone arginine methyltransferase purified from rat liver cytoplasm.
Topics: Acridines; Adenine; Adenosine; Animals; Arginine; Azo Compounds; Carbon Radioisotopes; Carcinogens; Cytoplasm; Dimethylformamide; Ethidium; Ethionine; Fluorenes; Histones; Homocysteine; Liver; Male; Mesylates; Methylation; Methyltransferases; Nitrosamines; Nitrosoguanidines; Nitrosourea Compounds; Pyrimidines; Pyrroles; Rats; Ribonucleosides; S-Adenosylmethionine | 1974 |
Biogenesis of cocarboxylase in Escherichia coli: regulatory properties of thiamine monophosphate kinase.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Escherichia coli; Magnesium; Organophosphorus Compounds; Phosphotransferases; Phosphotransferases (Phosphate Group Acceptor); Potassium; Thiamine; Thiamine Pyrophosphate | 1973 |
N6-substituted adenines induce cell elongation irrespective of the intracellular cyclic AMP levels.
Topics: Adenine; Adenosine; Animals; Cell Adhesion; Cell Movement; Cell-Free System; Cells, Cultured; Cyclic AMP; Fibroblasts; L Cells; Mice; Microscopy, Phase-Contrast; Phosphoric Diester Hydrolases; Purines; Theophylline; Tritium; Xanthines | 1974 |
Stimulation of brain aromatic alkylamine N-methyltransferase activity by FAD and methylcobalamin.
Topics: Adenine; Adenine Nucleotides; Adenosine; Allosteric Regulation; Amines; Aminophylline; Animals; Binding Sites; Brain; Carbon Radioisotopes; Cyclic AMP; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Kinetics; Mercaptoethanol; Methyltransferases; NAD; Oxidation-Reduction; Papaverine; Protein Binding; Rats; Tetrahydrofolates; Vitamin B 12 | 1974 |
Reaction of adenosine with ethylating agents.
Topics: Adenine; Adenine Nucleotides; Adenosine; Alkylating Agents; Carbon Radioisotopes; Chromatography, Paper; Drug Stability; Electrophoresis, Paper; Fluorescence; Hydrocarbons, Iodinated; Hydrogen-Ion Concentration; Imidazoles; Mesylates; Poly A-U; Polynucleotides; Purine Nucleosides; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Sulfuric Acids | 1974 |
Uptake and relase of (14C)adenine derivatives at beds of mammalian cortical synaptosomes in a superfusion system.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Biological Transport; Carbon Radioisotopes; Cerebral Cortex; Cyclic AMP; Electric Stimulation; Hypoxanthines; Inosine; Lactates; Mitochondria; Nylons; Potassium Chloride; Spectrometry, Fluorescence; Synaptosomes; Tetrodotoxin; Time Factors | 1974 |
Regulation of adenosine 3':5'-monophosphate content in human astrocytoma cells by adenosine and the adenine nucleotides.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Astrocytoma; Biological Transport; Carbon Radioisotopes; Cell Line; Chromatography, Ion Exchange; Chromatography, Paper; Clone Cells; Cyclic AMP; Humans; Kinetics; Norepinephrine; Papaverine; Phentolamine; Phosphoric Diester Hydrolases; Propranolol; Receptors, Drug; Theophylline; Time Factors; Tritium; Xanthines | 1974 |
Cyclic AMP as a cell surface activating agent in Dictyostelium discoideum.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Cell Membrane; Chromatography, Thin Layer; Cyclic AMP; Isotope Labeling; Kinetics; Myxomycetes; Phosphates; Phosphorus Radioisotopes; Time Factors; Tritium | 1974 |
Stimulated formation of cyclic adenosine 3':5'-monophosphate by aspartate and glutamate in cerebral cortical slices of guinea pig.
Topics: Adenine; Adenosine; Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Calcium; Carbon Radioisotopes; Cerebral Cortex; Cocaine; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Glutamates; Guinea Pigs; Kinetics; Male; Phosphoric Diester Hydrolases; Stereoisomerism; Stimulation, Chemical; Structure-Activity Relationship; Theophylline | 1974 |
The aggregation of rabbit polymorphonuclear leucocytes: effects of antimitotic agents, cyclic nucleotides and methyl xanthines.
Topics: Adenine; Adenosine; Animals; Bucladesine; Caffeine; Cell Aggregation; Colchicine; Cyclic AMP; Cyclic GMP; Depression, Chemical; In Vitro Techniques; Leukocytes; Nucleotides, Cyclic; Rabbits; Stimulation, Chemical; Theobromine; Theophylline; Vinblastine; Xanthines | 1974 |
Effect of pharmacological agents on human keratinocyte mitosis in vitro. I. Inhibition by adenine nucleotides.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Bucladesine; Cells, Cultured; Cyclic AMP; Cyclic GMP; Cytidine; Cytosine Nucleotides; Depression, Chemical; Guanine; Guanine Nucleotides; Guanosine; Guanosine Triphosphate; Humans; Hypoxanthines; Inosine; Inosine Nucleotides; Mitosis; Skin; Thymine Nucleotides; Uracil Nucleotides | 1974 |
Cytokinins: formation of the nucleoside-5'-triphosphate in tobacco and Acer cells.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Triphosphatases; Alkaline Phosphatase; Animals; Carbon Radioisotopes; Cell Line; Chromatography, Paper; Chromatography, Thin Layer; Electrophoresis, Paper; Nicotiana; Nucleotidases; Phosphoric Monoester Hydrolases; Plants; Plants, Toxic; Pyruvate Kinase; Snakes; Species Specificity; Venoms | 1974 |
A simple method for routine determination of adenylate cyclase activity in intact fat cells.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenylyl Cyclases; Adipose Tissue; Adrenocorticotropic Hormone; Aluminum; Animals; Carbon Radioisotopes; Chromatography; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cyclic AMP; Epididymis; Evaluation Studies as Topic; In Vitro Techniques; Male; Methods; Norepinephrine; Phosphorus Radioisotopes; Rats; Time Factors; Tritium | 1974 |
Human IMP dehydrogenase. Kinetics and regulatory properties.
Topics: Adenine; Adenosine; Carbon Radioisotopes; Cell Fractionation; Chromatography, DEAE-Cellulose; Chromatography, Paper; Cytosol; Female; Guanine; Guanosine; Humans; Inosine Nucleotides; Ketone Oxidoreductases; Kinetics; Mercaptopurine; Mitochondria; NAD; Placenta; Pregnancy; Purine Nucleotides; Pyrimidine Nucleotides; Structure-Activity Relationship; Ultracentrifugation | 1974 |
Interrelationships among the levels of ATP, adenosine and cyclic AMP in incubated slices of guinea-pig cerebral cortex: effects of depolarizing agents, psychotropic drugs and metabolic inhibitors.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antimetabolites; Batrachotoxins; Carbon Radioisotopes; Cerebral Cortex; Chlorpromazine; Chromatography, Ion Exchange; Chromatography, Thin Layer; Clomipramine; Cyclic AMP; Dibenzazepines; Guinea Pigs; Histamine; In Vitro Techniques; Male; Norepinephrine; Ouabain; Potassium; Prenylamine; Serotonin; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Time Factors; Veratrine | 1974 |
Effect of cyclic AMP on nucleoside metabolism. III. Effect on uridine incorporation in monkey (CV-1) cells.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Bucladesine; Cell Line; Chromatography, Paper; Cyclic AMP; Haplorhini; Kidney; Kinetics; Phosphorus Radioisotopes; RNA; Solubility; Time Factors; Transcription, Genetic; Uridine | 1974 |
Different half-lives of nicotinamide and adenine moieties of NAD in HeLa S3 cultures.
Topics: Adenine; Adenosine; Carbon Radioisotopes; Chromatography, Ion Exchange; Half-Life; HeLa Cells; Humans; Isotope Labeling; Kinetics; NAD; Niacinamide; Nicotinic Acids; Time Factors; Triaziquone | 1973 |
Reaction of methyl methanesulphonate with nucleic acids of fetal and newborn rats in vivo.
Topics: Adenine; Adenosine; Animals; Animals, Newborn; Autoradiography; Carbon Radioisotopes; Cytidine; DNA; Female; Fetus; Gestational Age; Guanine; Guanosine; Hydrolysis; Injections, Intraperitoneal; Maternal-Fetal Exchange; Mesylates; Methylation; Nucleic Acids; Pregnancy; Rats; Rats, Inbred Strains; RNA; Time Factors | 1974 |
Purification and characterization of adenosine-adenosine cyclic 3',5'-monophosphate binding protein factors from rabbit erythrocytes.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Binding Sites; Carrier Proteins; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Cyclic AMP; Electrophoresis, Disc; Erythrocytes; Kinetics; Molecular Weight; Phosphorus Radioisotopes; Protamines; Protein Binding; Protein Conformation; Protein Kinases; Rabbits; Receptors, Drug; Tritium; Urea | 1974 |
Theophylline inhibition of nucleoside transport and its relation to cyclic AMP in skeletal muscle.
Topics: Adenine; Adenosine; Animals; Biological Transport; Bucladesine; Caffeine; Carbon Radioisotopes; Chromatography, Paper; Cyclic AMP; Hypoxanthines; In Vitro Techniques; Inosine; Isoproterenol; Muscle Contraction; Muscles; Nucleosides; Phenytoin; Propranolol; Protein Binding; Purines; Rana pipiens; Ribose; Sorbitol; Theophylline; Tritium; Uridine | 1974 |
Cyclic AMP-induced tyrosinase synthesis in Neurospora crassa.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Bucladesine; Caffeine; Catechol Oxidase; Cyclic AMP; Cycloheximide; Enzyme Induction; Neurospora; Neurospora crassa; Theophylline | 1974 |
[Demonstration of 2 compartments of cyclic AMP in suspensions of human platelets].
Topics: Adenine; Adenosine; Adenylyl Cyclases; Autoantibodies; Blood Platelets; Collagen; Cyclic AMP; Gliclazide; Humans; In Vitro Techniques; Prostaglandins E; Thrombin | 1974 |
Carbon dioxide fixation by isolated chloroplasts of Egulena gracilis. II. Inhibition of CO 2 fixation by AMP.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Carbon Dioxide; Carbon Isotopes; Chloroplasts; Euglena gracilis; Light; NADP; Nucleotides; Pentosephosphates; Phosphotransferases; Photophosphorylation; Purines; Radiation Effects | 1972 |
Output of ( 14 C)adenine derivatives on electrical excitation of tissues from the brain: calcium ion-sensitivity and an accompanying re-uptake process.
Topics: Adenine; Adenine Nucleotides; Adenosine; Brain; Calcium; Carbon Isotopes; Cyclic AMP; Electric Stimulation; Hypoxanthines; In Vitro Techniques; Inosine; Neurotransmitter Agents | 1972 |
Cyclic adenosine 3',5'-monophosphate in guinea pig cerebral cortical slices. 3. Formation, degradation, and reformation of cyclic adenosine 3',5'-monophosphate during sequential stimulations by biogenic amines and adenosine.
Topics: Adenine; Adenosine; Animals; Biogenic Amines; Carbon Isotopes; Cerebral Cortex; Cyclic AMP; Drug Synergism; Guinea Pigs; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Male; Norepinephrine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Time Factors; Tritium; Veratrine | 1973 |
Mercuration of modified nucleotides: chemical methods toward nucleic acid sequencing by electron microscopy.
Topics: Adenine; Adenosine; Alkenes; Base Sequence; Chemical Phenomena; Chemistry; Cytidine; Cytosine; DNA; Kinetics; Mercury; Microscopy, Electron; Nucleotides; Purines | 1974 |
Self-association studies of two adenine derivatives by equilibrium ultracentrifugation.
Topics: Adenine; Adenosine; Binding Sites; Calorimetry; Chemical Phenomena; Chemistry, Physical; Chromatography, Thin Layer; Kinetics; Mathematics; Methane; Methanol; Molecular Conformation; Molecular Weight; Spectrophotometry, Ultraviolet; Temperature; Thermodynamics; Ultracentrifugation | 1974 |
Nucleic acid precursor incorporation by Eimeria nieschulzi (Protozoa: Apicomplexa) and jejunal villus epithelium.
Topics: Adenine; Adenosine; Animals; Autoradiography; Coccidiosis; DNA; Eimeria; Epithelium; Guanosine; Jejunum; Male; Rats; RNA; Thymidine; Tritium | 1974 |
Biotransformation of 9-beta-D-arabinofurano-syladenine by rat and human erythrocytes.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Arabinose; Biotransformation; Blood Proteins; Carbon Radioisotopes; Chromatography, Thin Layer; Erythrocytes; Humans; Hypoxanthines; In Vitro Techniques; Inosine Nucleotides; Kinetics; Macaca mulatta; Male; Nucleosides; Rats; Time Factors; Tritium | 1974 |
Characterization of the steady-state population of messenger RNA and its poly(adenylic acid) segment in mammalian cells.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Base Sequence; Carbon Radioisotopes; Centrifugation, Zonal; Isotope Labeling; Mice; Molecular Weight; Neoplasms, Experimental; Polyribosomes; Rabbits; Reticulocytes; RNA, Messenger; RNA, Neoplasm; RNA, Ribosomal; Sarcoma; Time Factors; Tritium | 1974 |
Adenine nucleosides in solution: stabilisation of the anti-conformation by C-5' substituents.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Aminohydrolases; Binding Sites; Circular Dichroism; Deuterium; Dimethyl Sulfoxide; Magnetic Resonance Spectroscopy; Molecular Conformation; Muscles; Optical Rotatory Dispersion; S-Adenosylmethionine; Solvents; Spectrophotometry, Ultraviolet | 1974 |
Biochemical and genetic studies of laboratory purine auxotrophic strains of Micrococcus luteus.
Topics: Adenine; Adenosine; Carbon Dioxide; Crosses, Genetic; Hypoxanthines; Imidazoles; Inosine; Micrococcus; Mutation; Purines; Recombination, Genetic; Ribonucleotides; Transformation, Genetic | 1974 |
Presence of heterodisperse nuclear RNA in a plant: Zea mays.
Topics: Adenine; Adenosine; Cell Nucleus; Cytosine; Guanine; Molecular Weight; Plants; RNA; Tritium; Uracil; Zea mays | 1974 |
Chemistry and pharmacology of apiose. 7. Susceptibility of some branched-chain sugar nucleosides to enzymatic deamination.
Topics: Adenine; Adenosine; Aminohydrolases; Animals; Cattle; Deamination; Intestines; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Nucleosides; Pentoses; Protein Binding; Stereoisomerism; Structure-Activity Relationship; Xylose | 1974 |
Effect of concanavalin A on phagocytosis.
Topics: Adenine; Adenosine; Animals; Biological Transport; Cell Membrane Permeability; Concanavalin A; Glucose; In Vitro Techniques; Lactose; Lectins; Leukocytes; Maltose; Phagocytosis; Polyvinyls; Rabbits; Ribose; Suspensions; Temperature | 1972 |
Inhibition of adenosine uptake by platelets.
Topics: Adenine; Adenosine; Blood Platelets; Buffers; Carbon Isotopes; Dipyridamole; Drug Synergism; Humans; Hypoxanthines; In Vitro Techniques; Inosine; Uric Acid | 1972 |
Identification of the enzymatic pathways of nucleotide metabolism in human lymphocytes and leukemia cells.
Topics: Adenine; Adenine Nucleotides; Adenosine; Aminohydrolases; Animals; Cell Fractionation; Cell Line; Child; Cytidine; Guanine; Guanine Nucleotides; Humans; Leukemia, Lymphoid; Lymphocytes; Male; Nucleotides; Pentosyltransferases; Phosphotransferases; Purine Nucleotides; Purines; Pyrimidines; Sarcoma 180; Xanthine Oxidase | 1973 |
Mitochondrial protein synthesis: RNA with the properties of Eukaryotic messenger RNA.
Topics: Adenine; Adenosine; Camptothecin; Carbon Isotopes; Cell Fractionation; Cell Nucleus; Deoxyribonucleases; Electrophoresis, Polyacrylamide Gel; HeLa Cells; Humans; Mitochondria; Polynucleotides; Puromycin; Ribonucleases; RNA; RNA, Messenger; Tritium; Uridine | 1973 |
Polyadenylic acid segment in mRNA becomes shorter with age.
Topics: Adenine; Adenine Nucleotides; Adenosine; Amino Acids; Carbon Isotopes; Cell Fractionation; Cytoplasm; Dactinomycin; Electrophoresis; Emetine; Female; HeLa Cells; Humans; Kinetics; Neoplasm Proteins; Phosphorus Isotopes; Polynucleotides; Ribonucleases; RNA, Messenger; RNA, Neoplasm; Tritium | 1973 |
Solution studies of the nucleic acid bases and related model compounds. Solubility in aqueous alcohol and glycol solutions.
Topics: 1-Propanol; Adenine; Adenosine; Butanols; Cytosine; Deoxyadenosines; Ethanol; Glycols; Guanosine; Mathematics; Methanol; Nucleic Acid Denaturation; Nucleosides; Solubility; Spectrophotometry, Ultraviolet; Thermodynamics; Thymine; Uracil; Water | 1972 |
Adenosine aminohydrolase from Halobacterium cutirubrum.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Aminohydrolases; Ammonium Sulfate; Chemical Precipitation; Chromatography, Gel; Cytidine; Deoxyadenosines; Dextrans; Enzyme Activation; Glycols; Guanine; Halobacterium; Hydrogen-Ion Concentration; Kinetics; Molecular Weight; Nucleosides; Polyethylenes; Sodium Chloride; Structure-Activity Relationship | 1973 |
Nucleoside antibiotics. Biosynthesis of arabinofuranosyladenine by Streptomyces antibioticus.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Anti-Bacterial Agents; Arabinose; Carbon Isotopes; Chromatography, Paper; Cytidine; Cytosine Nucleotides; Glucose; Isomerism; Nucleosides; Ribose; RNA, Bacterial; Streptomyces; Streptomyces antibioticus | 1972 |
Partial purification and characterization of S-adenosylhomocysteine hydrolase isolated from Saccharomyces cerevisiae.
Topics: Acetone; Adenine; Adenosine; Aminohydrolases; Carbon Isotopes; Cell-Free System; Chemical Precipitation; Chromatography, Gel; Chromatography, Paper; Dextrans; Homocysteine; Hydrolases; Hydroxyapatites; Nucleosides; Nucleotides; Ribonucleosides; Saccharomyces cerevisiae; Ultracentrifugation | 1972 |
Adenosine uptake by isolated membrane vesicles from Escherichia coli K-12.
Topics: Adenine; Adenosine; Ascorbic Acid; Azides; Biological Transport, Active; Caffeine; Carbon Radioisotopes; Cell Membrane; Chloromercuribenzoates; Escherichia coli; Iodoacetates; Kinetics; Maleimides; Microscopy, Electron; Mutation; Organoids; Phenazines; Ribonucleosides; Time Factors | 1973 |
Labeling of sporozoites of Plasmodium berghei with tritiated purines.
Topics: Adenine; Adenosine; Animals; Anopheles; Blood; Deoxyadenosines; Deoxyribonucleosides; Guanosine; Isotope Labeling; Malaria; Mice; Orotic Acid; Plasmodium berghei; Purines; Salivary Glands; Thymidine; Tritium | 1974 |
[Enzymatic degradation of kinetin and certain N6-substituted adenines, in Schizosaccharomyces pombe].
Topics: Adenine; Adenosine; Aminohydrolases; Ascomycota; Carbon Isotopes; Hypoxanthines; Kinetics; Plant Growth Regulators; Purines; Spectrophotometry; Time Factors | 1972 |
Effect of AMP and related compounds on glycogen content of Tetrahymena.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Anaerobiosis; Animals; Carbon Dioxide; Carbon Isotopes; Cell Count; Culture Media; Cytidine; Glycogen; Glyoxylates; Inosine; Lipid Metabolism; Tetrahymena pyriformis; Uridine | 1972 |
Crystal structure of the aminoglycosyl antibiotic puromycin dihydrochloride pentahydrate. Models for the terminal 3'-aminoacyladenosine moieties of transfer RNA's and protein-nucleic acid interactions.
Topics: Adenine; Adenosine; Chlorides; Hydrogen; Models, Structural; Molecular Conformation; Nucleic Acids; Phenylalanine; Proteins; Protons; Puromycin; Ribose; RNA, Transfer; Water; X-Ray Diffraction | 1972 |
1-methyladenosine ribohydrolase in the starfish ovary and its relation to oocyte maturation.
Topics: Adenine; Adenosine; Ammonium Sulfate; Animals; Chemical Precipitation; Chromatography, Gel; Chromatography, Thin Layer; Female; Glycoside Hydrolases; Gonads; Hot Temperature; Hydrogen-Ion Concentration; Isoelectric Focusing; Male; Methane; Molecular Weight; Ovary; Ovum; Peptides; Seawater; Starfish; Testis; Tissue Extracts | 1972 |
Solvolysis of adenine nucleosides. I. Effects of sugars and adenine substituents on acid solvolyses.
Topics: Acids; Adenine; Adenosine; Chemical Phenomena; Chemistry; Hydrogen-Ion Concentration; Nucleosides; Ribose; Solubility; Spectrophotometry; Thermodynamics | 1972 |
Solvolysis of adenine nucleosides. II. Effects of sugars and adenine substituents on alkaline solvolyses.
Topics: Adenine; Adenosine; Alkalies; Chemical Phenomena; Chemistry; Chromatography, Paper; Hydrogen-Ion Concentration; Kinetics; Nucleosides; Ribose; Solubility | 1972 |
Raphanatin, an unusual purine derivative and a metabolite of zeatin.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Butylamines; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Paper; Chromatography, Thin Layer; Glycosides; Mass Spectrometry; Plant Growth Regulators; Plants; Purine Nucleotides; Purines; Ribonucleosides; Spectrophotometry, Ultraviolet; Tritium; Zeatin | 1972 |
A 13 C nuclear-magnetic-resonance study of the enzyme cofactor flavin-adenine dinucleotide.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Carbon Isotopes; Chemical Phenomena; Chemistry; Deuterium; Flavin-Adenine Dinucleotide; Fourier Analysis; Magnetic Resonance Spectroscopy; Riboflavin | 1972 |
[Influence of adenine and adenosine concentrations in plasma on the adenine nucleotide content of erythrocytes. I. Comparative studies in ACD-preserved blood with and without addition of adenine].
Topics: Adenine; Adenine Nucleotides; Adenosine; Blood Preservation; Citrates; Erythrocytes; Glucose; Humans | 1972 |
Effects of persantin on several transport systems of murine leukemias.
Topics: Adenine; Adenosine; Amino Acids; Animals; Biological Transport; Cell Line; Cyclopentanes; Cytidine; Depression, Chemical; Dipyridamole; Fucose; Glucose; Glycerol; Leukemia L1210; Leukemia, Experimental; Mice; Phosphates; Uracil; Uridine | 1972 |
A quantitative limit for cytokinin incorporation into transfer ribonucleic acid by soya-bean callus tissue.
Topics: Adenine; Adenosine; Benzyl Compounds; Glycine max; Hydrolysis; Molecular Weight; Plant Growth Regulators; Plants; RNA, Transfer; Tritium; Uridine | 1972 |
Pathways of nucleotide metabolism in Schistosoma mansoni. II. Disposition of adenosine by whole worms.
Topics: Adenine; Adenine Nucleotides; Adenosine; Aminohydrolases; Animals; Carbon Isotopes; Culture Media; Erythrocytes; Hydrogen-Ion Concentration; In Vitro Techniques; Inosine; Inosine Nucleotides; Mice; Nucleosides; Pentosyltransferases; Purines; Ribose; Schistosoma mansoni; Time Factors | 1973 |
Pathways of nucleotide metabolism in Schistosoma mansoni. 3. Identification of enzymes in cell-free extracts.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Aminohydrolases; Animals; Carbon Isotopes; Cell-Free System; Chromatography, Thin Layer; Creatine Kinase; Cytidine; Freeze Drying; Guanine; Hypoxanthines; Mice; Mice, Inbred Strains; Nucleotides; Pentosyltransferases; Phosphotransferases; Purines; Schistosoma mansoni; Time Factors | 1973 |
[Identification of atypical adenine decomposition products of isolated epidermis in the hairless mouse].
Topics: Adenine; Adenosine; Animals; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography; Chromatography, Paper; Deamination; In Vitro Techniques; Mice; Mice, Inbred Strains; Purines; Skin; Spectrum Analysis; Xanthine Oxidase | 1973 |
Nucleoside antibiotics. Epimerization of carbon 2' of adenosine during the biosynthesis of 9- -D--arabinofuranosyladenine by Streptomyces antibioticus.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Ammonium Chloride; Anti-Bacterial Agents; Arabinose; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Paper; Hydrolysis; Isomerism; Isotope Labeling; Mass Spectrometry; Nitrogen Isotopes; Nucleosides; Ribose; RNA, Bacterial; Spectrophotometry, Ultraviolet; Streptomyces; Tritium | 1973 |
Spectrophotometric evidence for the formation of a 2-nickel-adenosine triphosphate complex.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Chemical Phenomena; Chemistry; Fluorescence; Hydrogen-Ion Concentration; Ligands; Mathematics; Nickel; Osmolar Concentration; Protein Binding; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1973 |
Sugar-modified N 6 -(3-methyl-2-butenyl)adenosine derivatives, N 6 -benzyl analogs, and cytokinin-related nucleosides containing sulfur or formycin.
Topics: Adenine; Adenosine; Alkenes; Alkylation; Benzyl Compounds; Chromatography, Thin Layer; Growth Substances; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microchemistry; Nucleosides; Spectrophotometry, Ultraviolet; Sulfur | 1973 |
Metabolism of N-(purin-6-ylcarbamoyl)-L-threonine riboside in rat and man.
Topics: Adenine; Adenosine; Administration, Oral; Animals; Carbamates; Carbon Isotopes; Chromatography, Paper; Drug Stability; Humans; In Vitro Techniques; Injections, Intravenous; Liver; Purines; Rats; Ribonucleosides; RNA, Transfer; Threonine | 1973 |
Absence of demonstrable linkage of human genes for enzymes of the purine and pyrimidine salvage pathways in human-mouse somatic cell hybrids.
Topics: Adenine; Adenosine; Alkaline Phosphatase; Aminohydrolases; Animals; Cell Line; Cytidine; Diploidy; Electrophoresis; Fibroblasts; Guanine; HeLa Cells; Humans; Hybrid Cells; Hypoxanthines; Isoelectric Focusing; L Cells; Mice; Nucleotidases; Pentosyltransferases; Phosphotransferases; Purines; Pyrimidines; Thymidine Kinase | 1973 |
Effect of anoxia on sugar transport in avian erythrocytes.
Topics: Adenine; Adenosine; Aerobiosis; Anaerobiosis; Animals; Biological Transport; Blood Glucose; Buffers; Calcium; Carbon Isotopes; Erythrocytes; Geese; Glucose; Hypoxia; Magnesium; Phosphates; Potassium; Ribonucleotides; Sodium; Sorbitol; Time Factors; Water | 1973 |
The reaction of 14C-labelled platinum ethylenediamine dichloride with adenine compounds and DNA.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Animals; Binding Sites; Calorimetry; Carbon Isotopes; Cattle; Chlorides; DNA; Ethylenediamines; Kinetics; Molecular Conformation; Nucleic Acid Conformation; Platinum; Polynucleotides; Temperature; Thermodynamics; Thymus Gland; Time Factors | 1973 |
Interconversions of hexofuranosyl nucleosides. V. Synthesis and reexamination of the structure of 9-(6-deoxy-alpha-L-mannofuranosyl)adenine.
Topics: Adenine; Adenosine; Chromatography, Paper; Deoxy Sugars; Mannose; Molecular Conformation; Nucleosides; Optical Rotation; Stereoisomerism | 1973 |
The glucosylation of cytokinins.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Amino Alcohols; Benzyl Compounds; Chromatography, DEAE-Cellulose; Chromatography, Paper; Chromatography, Thin Layer; Glycosides; Plant Growth Regulators; Plants; Purines; Ribonucleosides; Ribonucleotides; Spectrophotometry, Ultraviolet; Tritium | 1973 |
Development of defined media for growth of Trypanosoma brucei sspp.
Topics: Adenine; Adenosine; Bicarbonates; Buffers; Cell Count; Citrates; Culture Media; Glucosamine; Guanine; Guanosine; Hydrogen-Ion Concentration; Proline; Succinates; Trypanosoma brucei brucei | 1973 |
[Effect of plasma adenine and adenosine concentration on adenine nucleotid content of erythrocytes. II. Longitudinal studies on erythrocytes of varying density from ACD-adenine preserved blood using density gradient centrifugation in a dextran medium].
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Blood Preservation; Centrifugation, Density Gradient; Dextrans; Erythrocytes; Female; Glucosephosphate Dehydrogenase; Hemoglobins; Humans; Male; Time Factors | 1973 |
A role of liver adenosine in the renewal of the adenine nucleotides of human and rabbit erythrocytes.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Erythrocytes; Humans; Hypoxanthines; Inosine; Kinetics; Liver; Models, Biological; Perfusion; Rabbits; Species Specificity; Time Factors; Tritium; Xanthines | 1973 |
Purine metabolism in intact erythrocytes from controls and HG-PRT deficient individuals.
Topics: Adenine; Adenosine; Carbon Radioisotopes; Cell Membrane; Erythrocytes; Guanine; Guanine Nucleotides; Humans; Hypoxanthines; Inosine Nucleotides; Kinetics; Pentosephosphates; Pentosyltransferases; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Time Factors | 1973 |
A comparative study on the restoration of radiation-induced damage in mice and in cultured mouse L cells.
Topics: Adenine; Adenosine; Animals; Cell Survival; Deoxyribonucleosides; L Cells; Male; Mice; Radiation Effects; Radiation Injuries, Experimental | 1973 |
5'-Methylthioadenosine and related compounds as precursors of S-adenosylmethionine in yeast.
Topics: Adenine; Adenosine; Aerobiosis; Candida; Carbon Radioisotopes; Deoxyadenosines; Methionine; Optical Rotation; S-Adenosylmethionine; Spectrophotometry, Ultraviolet; Sulfides; Sulfur Radioisotopes; Thionucleosides; Time Factors | 1973 |
Rapid equilibration of adenosine with the ATP pool of mammalian cells.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Chromatography, Thin Layer; Guanine Nucleotides; L Cells; Methods; Mice; RNA; Tritium | 1973 |
Enzyme inhibitors. 26. Bridging hydrophobic and hydrophilic regions on adenosine deaminase with some 9-(2-hydroxy-3-alkyl)adenines.
Topics: Adenine; Adenosine; Aminohydrolases; Animals; Binding Sites; Cattle; Intestinal Mucosa; Molecular Conformation; Stereoisomerism; Structure-Activity Relationship | 1974 |
The formation of adenosine in rabbit liver and its possible role as a direct precursor of erythrocyte adenine nucleotides.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Chromatography, Ion Exchange; Chromatography, Paper; Erythrocytes; Humans; Hypoxanthines; Liver; Perfusion; Purine Nucleotides; Rabbits; Species Specificity; Spectrophotometry, Ultraviolet; Time Factors; Tritium | 1974 |
Production of flavine-adenine dinucleotide from riboflavine by a mutant of Sarcina lutea.
Topics: Acetates; Adenine; Adenosine; Air; Aminohydrolases; Culture Media; Cycloserine; Fermentation; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Guanine; Hydrogen-Ion Concentration; Mutation; Penicillins; Riboflavin; Sarcina; Sodium; Streptomycin; Surface-Active Agents; Thiamine | 1974 |
Nucleic acid related compounds. 11. Adenosine 2',3'-ribo-epoxide. Synthesis, intramolecular degradation, and transformation into 3'-substituted xylofuranosyl nucleosides and the lyxo-epoxide.
Topics: Adenine; Adenosine; Ethers, Cyclic; Molecular Weight; Nucleic Acids; Nucleosides; Ribonucleosides; Xylose | 1974 |
Studies on the molecular complex of flavins. V. Possible role of free sulfhydryl group in apoprotein of glucose oxidase and 6-amino group in adenine moiety of FAD.
Topics: Adenine; Adenosine; Apoproteins; Aspergillus; Chloromercuribenzoates; Dithiothreitol; Flavin-Adenine Dinucleotide; Glucose Oxidase; Sulfhydryl Compounds | 1974 |
The separation of certain bases, nucleosides, and nucleotides related to adenine by continuous-flow electrophoresis.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Electrophoresis; Guanine Nucleotides; Inosine; Methods; Nucleosides; Nucleotides | 1974 |
A new method to determine sugar-base torsion in purine nucleosides and nucleotides.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Binding Sites; Bromine; Deuterium; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Manganese; Molecular Conformation; Ribose | 1974 |
Influence of cytokinins and sulfhydryl group-reacting agents on calcium transport in fungi.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Benzimidazoles; Binding Sites; Biological Transport; Calcium; Calcium Radioisotopes; Cell Membrane; Cell Wall; Depression, Chemical; Fungi; Glycopeptides; Hydrogen-Ion Concentration; Hydroxymercuribenzoates; Iodine; Kinetics; Mercury; Osmosis; Ruthenium; Silver; Stimulation, Chemical; Sulfhydryl Reagents; Temperature | 1974 |
Chinese hamster cells exhibiting a temperature dependent alteration in purine transport.
Topics: Adenine; Adenosine; Animals; Antimetabolites; Azaguanine; Biological Transport; Carbon Radioisotopes; Cell Division; Cell Line; Cricetinae; Female; Guanine; Guanosine; Hybrid Cells; Hypoxanthines; Inosine Nucleotides; Kinetics; Ovary; Pentosephosphates; Pentosyltransferases; Phenotype; Purines; Temperature; Thymidine | 1974 |
Quantitative studies of the release of purine compounds following stimulation of non-adrenergic inhibitory nerves in the stomach.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Bufo marinus; Chromatography, Paper; Electric Stimulation; Gastric Mucosa; In Vitro Techniques; Inosine; Kinetics; Neurons; Nucleosides; Nucleotides; Perfusion; Purines; Spectrophotometry; Stimulation, Chemical; Stomach; Time Factors; Ultraviolet Rays; Vagus Nerve | 1971 |
Metabolic significance of adenosine in the mouse erythrocytes.
Topics: Adenine; Adenine Nucleotides; Adenosine; Alkaline Phosphatase; Aminohydrolases; Animals; Carbon Isotopes; Chromatography; Erythrocytes; Hypoxanthines; In Vitro Techniques; Inosine; Intestine, Small; Kidney; Liver; Male; Mice; Myocardium; Nucleotides; Purines; Ribose; RNA | 1972 |
Kinetics of dissociation of polynucleotide-monomer complexes.
Topics: Adenine; Adenosine; Hydrogen-Ion Concentration; Kinetics; Macromolecular Substances; Models, Chemical; Polynucleotides; Temperature; Uracil Nucleotides; Viscosity | 1972 |
Release of adenine derivatives on electrical stimulation of superfused tissues from the brain.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Brain; Carbon Isotopes; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Perfusion; Rats | 1972 |
Adenine nucleotide salvage synthesis in the rat heart; pathways of adnosine salvage.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Aminohydrolases; Animals; Aspartic Acid; Carbon Isotopes; Female; Guanosine Triphosphate; Hypoxanthines; Inosine Nucleotides; Kinetics; Ligases; Lyases; Male; Myocardium; Pentosephosphates; Pentosyltransferases; Phosphotransferases; Rats; Spectrophotometry; Succinates; Ultraviolet Rays; Xanthine Oxidase | 1972 |
Analogs of S-adenosylhomocysteine as potential inhibitors of biological transmethylation. Synthesis and biological activity of homocysteine derivatives bridged to adenine.
Topics: Adenine; Adenosine; Catechol O-Methyltransferase Inhibitors; Chromatography, Ion Exchange; Chromatography, Thin Layer; Homocysteine; Methylation; Spectrum Analysis; Structure-Activity Relationship; Ultraviolet Rays | 1972 |
Studies on nucleotides and related compounds in plants. 3. Adenine and adenosine ratios in starch from potatoes held under prescribed conditions.
Topics: Adenine; Adenosine; Cold Temperature; Drug Stability; Food Preservation; Plants, Edible; Starch; Time Factors; Vegetables | 1972 |
Crystal structure of a naturally occurring dinucleoside phoaphate: uridylyl 3',5'-adenosine phosphate model for RNA chain folding.
Topics: Adenine; Adenosine; Base Sequence; Models, Structural; Nucleic Acid Conformation; Nucleosides; Oxygen; Ribose; RNA; Uracil; Uridine; X-Ray Diffraction | 1972 |
Adaptive significance of inosine and adenosine kinase activities in cultured human skin fibroblasts.
Topics: Adenine; Adenosine; Azaserine; Cells, Cultured; Fibroblasts; Guanine; Humans; Hypoxanthines; Inosine; Lesch-Nyhan Syndrome; Phosphotransferases; Skin; Thymidine; Tritium | 1972 |
Deamination of arabinosyladenine by adenosine deaminase and inhibition by arabinosyl-6-mercaptopurine.
Topics: Adenine; Adenosine; Aminohydrolases; Animals; Antibiotics, Antineoplastic; Arabinose; Cell Fractionation; Cell Line; Deamination; Drug Resistance; Female; Leukemia L1210; Mercaptopurine; Mice; Mice, Inbred Strains; Mutation; Nucleosides | 1972 |
Enzyme inhibitors. 25. An equation to calculate the unknown K i from two known values of K i in an R,S, and RS series. Stereoselectivity of inhibition of Adenosine deaminase by (R)-, (S)-, and (RS)-9-(1-hydroxy-2-alkyl and -aralkyl)adenines.
Topics: Adenine; Adenosine; Alkylation; Aminohydrolases; Animals; Cattle; Chemical Phenomena; Chemistry; Intestinal Mucosa; Nucleic Acid Conformation; Optical Rotation; Stereoisomerism | 1972 |
Metabolism of ( 14 C)adenine and derivatives by cerebral tissues, superfused and electrically stimulated.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Brain; Carbon Isotopes; Chromatography, Thin Layer; Electric Stimulation; Guinea Pigs; Hypoxanthines; In Vitro Techniques; Inosine; Lactates | 1972 |
Activation of 1-methyladenosine by starfish oocytes.
Topics: Adenine; Adenosine; Animals; Biological Transport; Female; Gonadotropins; Meiosis; Methane; Nucleosides; Nucleotides; Ovum; Radial Nerve; Starfish | 1972 |
Processing of adenovirus specific nuclear RNA during virus replication.
Topics: Adenine; Adenosine; Adenoviridae; Cell Nucleus; Centrifugation, Density Gradient; Cycloheximide; Dimethyl Sulfoxide; DNA, Viral; Genes; HeLa Cells; Humans; Molecular Weight; Nucleic Acid Hybridization; Polynucleotides; Polyribosomes; RNA, Messenger; RNA, Viral; Time Factors; Transcription, Genetic; Tritium; Uridine; Virus Replication | 1972 |
Effect of phagocytosis on membrane transport of nonelectrolytes.
Topics: Adenine; Adenosine; Animals; Biological Transport; Carbon Isotopes; Cell Membrane; Chloromercuribenzoates; Diffusion; Female; Kinetics; Lysine; Macrophages; Male; Mercury Isotopes; Methods; Neutrophils; Peritoneum; Phagocytosis; Rabbits; Tritium | 1971 |
Polyadenylic acid sequences: role in conversion of nuclear RNA into messenger RNA.
Topics: Adenine; Adenine Nucleotides; Adenosine; Autoradiography; Centrifugation, Density Gradient; Dactinomycin; Electrophoresis; Furans; HeLa Cells; Methanol; Ribonucleases; RNA; RNA, Messenger; Tritium | 1971 |
Inhibition of guanine metabolism of mammalian tumor cells by the carbocyclic analogue of adenosine.
Topics: Adenine; Adenocarcinoma; Adenosine; Carbon Isotopes; Cells, Cultured; Chromatography, Paper; Cyclopentanes; Guanine; Guanine Nucleotides; Hypoxanthines; Inosine Nucleotides; Kinetics; Neoplasms, Experimental; Pentosephosphates; Pentosyltransferases; Phosphotransferases | 1971 |
Effects of L-2-pyrrolidone-5-carboxylate on hepatic adenosine triphosphate levels in the ethionine-treated rat.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Antibiotics, Antineoplastic; Carbon Isotopes; Drug Antagonism; Ethionine; Female; Glycine; Liver; Pyrrolidinones; Rats | 1971 |
Adenine nucleotides and platelet function.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Biological Transport; Blood Platelets; Carbon Isotopes; Cell Membrane; Collagen; Energy Transfer; Ethanol; Hypoxanthines; Papaverine; Phosphorus Isotopes; Platelet Adhesiveness; Protein Binding; Thrombin | 1971 |
Factors affecting the rate of hydrated electron attack on polynucleotides.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Cytosine Nucleotides; Electrons; Hydrogen-Ion Concentration; Nucleic Acid Conformation; Polynucleotides; Radiation Effects; Time Factors; Uracil Nucleotides | 1971 |
Mass spectra of some heterocycles related to N 6 -( 2 -isopentenyl)adenosine.
Topics: Adenine; Adenosine; Alkenes; Mass Spectrometry; Methylation; Nucleosides; Pyrazoles; Pyrimidines; Pyrroles; Sulfides | 1971 |
Detailed comparison of the urinary excretion of purines in a patient with the Lesch-Nyhan syndrome and a control subject.
Topics: Adenine; Adenosine; Athetosis; Child; Chromatography, Gel; Chromatography, Ion Exchange; Formamides; Formates; Humans; Hypoxanthines; Imidazoles; Intellectual Disability; Lesch-Nyhan Syndrome; Male; Methods; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Ribonucleosides; Self Mutilation; Spectrophotometry; Ultraviolet Rays; Xanthines | 1970 |
The effect of 5-bromouracil on energy transfer in DNA and related model systems. Purine: pyrimidine crystal complexes.
Topics: Adenine; Adenosine; Bromouracil; Crystallography; DNA; Energy Transfer; Kinetics; Luminescent Measurements; Models, Chemical; Purines; Pyrimidines; Radiation Effects; Spectrum Analysis; Temperature; Thymine; Uracil; Uridine | 1971 |
The mechanism of aristeromycin. I. Growth inhibition of Xanthomonas oryzae by aristeromycin.
Topics: Adenine; Adenosine; Anti-Bacterial Agents; Cytidine; Cytosine; Deoxyuridine; Guanine; Guanosine; Hypoxanthines; Inosine; Nucleosides; Thymidine; Thymine; Uracil; Uridine; Xanthines; Xanthomonas | 1971 |
The reaction of adenosine with hydroxylamine.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Chromatography, Paper; Cytidine; Hydrogen-Ion Concentration; Hydroxylamines; Kinetics; Oxides; Spectrophotometry; Spectrum Analysis; Ultraviolet Rays | 1971 |
Pathways of purine ribonucleotide catabolism in Ehrlich ascites tumor cells in vitro.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cell Line; Guanine; Guanine Nucleotides; Guanosine; Hypoxanthines; Inosine; Inosine Nucleotides; Kinetics; Models, Biological; Nucleotides; Ribonucleosides; Ribonucleotides; Xanthines | 1971 |
Precursor pools and RNA synthesis in preimplantation mouse embryos.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Animals; Chromatography, Paper; Embryo Implantation; Embryo, Mammalian; Female; Gestational Age; Guanine; Mice; Mice, Inbred Strains; Purines; Pyrimidines; RNA; Spectrophotometry; Tritium; Uridine | 1971 |
Nucleosides. XIV. Synthesis of 3'-deoxyadenosine and 9-(3-deoxy- -L-threo-pentofuranosyl)adenine.
Topics: Adenine; Adenosine; Antibiotics, Antineoplastic; Deoxyadenosines; Deoxyribonucleosides; Methods; Nucleosides | 1971 |
Adenosine inhibits cell division and promotes neurite extension in PC12 cells.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenylyl Cyclases; Animals; Axons; Cell Division; Cell Line; Cyclic AMP; Drug Synergism; Nerve Growth Factors; Neurons; Receptors, Cell Surface; Receptors, Purinergic | 1984 |
[Effect of adenosine, AMP and papaverine on the cAMP content in thymocytes prelabelled with 14C-adenine].
Topics: Adenine; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Carbon Radioisotopes; Cell Compartmentation; Cyclic AMP; Papaverine; Rats; Rats, Inbred Strains; Thymus Gland | 1984 |
Adenosine A2 receptors on human monocytes modulate C2 production.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Complement C2; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Immunosuppressive Agents; Monocytes; Phenylisopropyladenosine; Receptors, Cell Surface; Receptors, Purinergic; Tubercidin | 1984 |
A new physiological function for adenosine: regulation of superoxide anion production.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Anions; Calcimycin; Concanavalin A; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1983 |
Neither vasoactive intestinal peptide (VIP) nor purine derivatives may mediate non-adrenergic tracheal inhibition.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Atropine; Carbachol; Electric Stimulation; Female; Guinea Pigs; Male; Muscle Relaxation; Muscle, Smooth; Purines; Synaptic Transmission; Theophylline; Trachea; Vasoactive Intestinal Peptide | 1984 |
Control of transmitter release in guinea-pig vas deferens by prejunctional P1-purinoceptors.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Triphosphate; Animals; Dipyridamole; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Neurotransmitter Agents; Norepinephrine; Receptors, Neurotransmitter; Receptors, Purinergic; Theophylline; Vas Deferens | 1984 |
Purine metabolism in mesophyll protoplasts of tobacco (Nicotiana tabacum) leaves.
Topics: Adenine; Adenosine; Guanine; Hypoxanthines; Nicotiana; Plants; Plants, Toxic; Protoplasts; Purines; RNA | 1980 |
Purine metabolism of erythrocytes in myotonic dystrophy.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Erythrocytes; Humans; Muscular Dystrophies; Purines | 1980 |
Methylxanthines modulate adenosine release from slices of cerebral cortex.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Adenosine Triphosphatases; Aminophylline; Animals; Caffeine; Cerebral Cortex; Cyclic AMP; gamma-Aminobutyric Acid; Male; Mice; Ouabain; Theophylline; Xanthines | 1981 |
Effect of inhibitors of transmethylation on histamine release from human basophils.
Topics: Adenine; Adenosine; Basophils; Calcimycin; Histamine Release; Homocysteine; Humans; Immunoglobulin E; In Vitro Techniques; Methylation; Ribonucleosides; S-Adenosylmethionine; Tubercidin | 1981 |
Inhibition of IgE-mediated histamine release from rat basophilic leukemia cells and rat mast cells by inhibitors of transmethylation.
Topics: Adenine; Adenosine; Animals; Basophils; Female; Histamine Release; Homocysteine; Immunoglobulin E; Leukemia; Mast Cells; Methylation; Mice; Rabbits; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1981 |
Effects of adenosine and deoxyadenosine on PHA-stimulation of lymphocytes of man, horse and pig.
Topics: Adenine; Adenosine; Adult; Animals; Deoxyadenosines; Horses; Humans; In Vitro Techniques; Lymphocytes; Phosphoribosyl Pyrophosphate; Phytohemagglutinins; Species Specificity; Swine; Thymidine; Uridine | 1982 |
Synergistic effect of purine derivatives on the toxicity of pyrazofurin and 6-azauridine towards cultured mammalian cells.
Topics: Adenine; Adenosine; Amides; Animals; Antimetabolites, Antineoplastic; Azauridine; Cell Line; Cell Survival; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Drug Synergism; Female; Hypoxanthines; Ovary; Purines; Pyrazoles; Ribonucleosides; Ribose; Structure-Activity Relationship | 1982 |
Effect of inhibitors of methylation on early and late interferon synthesis in bovine kidney cell cultures.
Topics: Adenine; Adenosine; Animals; Cattle; Cells, Cultured; Cycloheximide; Cycloleucine; Homocysteine; Interferons; Methylation; Newcastle disease virus; Poly I-C; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine | 1981 |
On the mechanism by which theophylline inhibits histamine release from rat mast cells.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Antigens; Cyclic AMP; Cyclic GMP; Histamine Release; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Rats; Rats, Inbred Strains; Species Specificity; Theophylline | 1982 |
The effect of methyltransferase inhibitors on histamine release from human dispersed lung mast cells activated with anti-human IgE and calcium ionophore A23187.
Topics: Adenine; Adenosine; Antibodies, Anti-Idiotypic; Calcimycin; Histamine Release; Humans; Immunoglobulin E; Mast Cells; Membrane Lipids; Methylation; Methyltransferases; Phospholipids; Ribonucleosides; S-Adenosylmethionine; Tubercidin | 1984 |
Inhibition of fast axonal transport by erythro-9-[3-(2-hydroxynonyl)]adenine.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Axonal Transport; Cycloleucine; Deoxyadenosines; Rana esculenta; Rana temporaria; Sciatic Nerve; Thionucleosides | 1984 |
Temperature-sensitive mutant rho-115 rho-RNA binary complexes, and stabilization by substrates and analogues.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Mutation; Poly C; Rho Factor; RNA, Messenger; Temperature; Transcription Factors | 1982 |
Azathioprine and 6-mercaptopurine (6-MP) suppress the human mixed lymphocyte reaction (MLR) by different mechanisms.
Topics: Adenine; Adenosine; Aminoimidazole Carboxamide; Azathioprine; DNA; Guanine; Humans; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Lymphocyte Culture Test, Mixed; Lymphocytes; Mercaptopurine; Xanthine; Xanthines | 1984 |
Molecular basis for the pharmacological actions of Clostridium botulinum type C2 toxin.
Topics: Adenine; Adenosine; Adenosine Diphosphate Ribose; Adenylyl Cyclases; Amino Acids; Animals; Chromatography, High Pressure Liquid; Hot Temperature; Mice; Molecular Weight; Niacinamide; Peptides; Toxoids | 1984 |
Purine-containing compounds, including cyclic adenosine 3',5'-monophosphate, induce fruiting of Myxococcus xanthus by nutritional imbalance.
Topics: Adenine; Adenosine; Cyclic AMP; Glycine; Hypoxanthines; Myxococcales; Purines | 1980 |
Effects of exogenous adenosine deaminase and erythro-9-(2-hydroxy-3-nonyl) adenine on intracellular cyclic AMP levels in C1300 murine neuroblastoma in tissue culture.
Topics: Adenine; Adenosine; Adenosine Deaminase; Animals; Cell Line; Culture Techniques; Cyclic AMP; Dipyridamole; Mice; Neoplasms, Experimental; Neuroblastoma; Nucleoside Deaminases; Theophylline | 1980 |
The effects of adenine derivatives on urate biosynthesis by isolated chicken liver cells [proceedings].
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Animals; Bucladesine; Chickens; Cyclic AMP; In Vitro Techniques; Liver; Uric Acid | 1980 |
Adenosine transport by a variant of C1300 murine neuroblastoma cells deficient in adenosine kinase.
Topics: Adenine; Adenosine; Adenosine Kinase; Animals; Biological Transport; Cell Line; Genetic Variation; Kinetics; Mice; Neuroblastoma; Phosphotransferases; Purines; Structure-Activity Relationship | 1980 |
Adenine nucleotide degradation by the obligate intracellular bacterium Rickettsia typhi.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Adenylate Kinase; ATP Synthetase Complexes; Biological Transport, Active; Multienzyme Complexes; Phosphotransferases; Rickettsia typhi | 1980 |
Role of adenylate cyclase in immunologic release of mediators from rat mast cells: agonist and antagonist effects of purine- and ribose-modified adenosine analogs.
Topics: Adenine; Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Binding Sites; Cyclic AMP; Hexosaminidases; Mast Cells; Rats; Secretory Rate | 1980 |
The quantitative relationship between intracellular concentration and egress of cyclic AMP from cultured cells.
Topics: Adenine; Adenosine; Adenylyl Cyclases; Cell Membrane; Cells, Cultured; Cyclic AMP; Fibroblasts; Humans; Intracellular Fluid; Kinetics; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases | 1981 |
Comparative effect of S-adenosyl-homocysteine (SAH) and Sinefungin on tRNA-base methylation in whole cells and in vitro.
Topics: Adenine; Adenosine; Animals; Antifungal Agents; Avian Sarcoma Viruses; Cell Transformation, Viral; Escherichia coli; Guanine; Homocysteine; Methylation; RNA, Transfer; S-Adenosylhomocysteine | 1981 |
Purine amplification of luteinizing hormone action in ovarian luteal cells.
Topics: 2-Chloroadenosine; Adenine; Adenine Nucleotides; Adenosine; Androgens; Animals; Corpus Luteum; Cyclic AMP; Female; Kinetics; Luteinizing Hormone; Progesterone; Purines; Rats | 1981 |
Eritadenine: a new tool for investigation of the adenosine P site in plasma membranes of rat fat cells.
Topics: Adenine; Adenosine; Adenylyl Cyclase Inhibitors; Adipose Tissue; Animals; Cell Membrane; Cyclic AMP; Dose-Response Relationship, Drug; In Vitro Techniques; Lipolysis; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1981 |
Role of membrane-bound 5'-nucleotidase in nucleotide uptake by the moderate halophile Vibrio costicola.
Topics: 5'-Nucleotidase; Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Biological Transport, Active; Cell Membrane; Kinetics; Magnesium; Nucleotidases; Vibrio | 1982 |
Highly activatable adenylate cyclase in [2-3H]adenine-prelabeled vesicles prepared from guinea pig cerebral cortex by a simplified procedure.
Topics: Adenine; Adenosine; Adenylyl Cyclases; Animals; Calcium; Cell Fractionation; Cerebral Cortex; Cyclic AMP; Epinephrine; Guinea Pigs; Histamine; Male; Microscopy, Electron | 1982 |
Inhibition by etazolate (SQ 20009) and cartazolate (SQ 65396) of adenosine-stimulated [3H]cAMP formation in [2-3H]adenine-prelabeled vesicles prepared from guinea pig cerebral cortex.
Topics: Adenine; Adenosine; Adenylyl Cyclases; Animals; Cerebral Cortex; Cyclic AMP; Enzyme Activation; Etazolate; Guinea Pigs; Nicotinic Acids; Pyrazoles | 1982 |
2-chloroadenosine increases calcium mobilization from mouse calvaria in vitro.
Topics: 2-Chloroadenosine; 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Adenosine; Animals; Bone and Bones; Bone Resorption; Calcium; Cells, Cultured; Cyclic AMP; Mice; Purines | 1982 |
Adenine-derived purines increase adenosine triphosphate (ATP) levels in the luteal cell: evidence that cell levels of ATP may limit the stimulation of adenosine 3',5'-monophosphate accumulation by luteinizing hormone.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Coformycin; Corpus Luteum; Cyclic AMP; Dinoprost; Dose-Response Relationship, Drug; Female; Luteinizing Hormone; Prostaglandins F; Purine Nucleosides; Rats | 1983 |
Inhibition of lymphocyte-mediated cytolysis and cyclic AMP phosphodiesterase by erythro-9-(2-hydroxy-3-nonyl)adenine.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenylyl Cyclases; Animals; Immunosuppressive Agents; In Vitro Techniques; Mice; S-Adenosylhomocysteine; T-Lymphocytes, Cytotoxic | 1982 |
Adenosine: a physiological modulator of superoxide anion generation by human neutrophils.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Deaminase; Calcimycin; Cell Aggregation; Coformycin; Cytochalasin B; Cytoplasmic Granules; Depression, Chemical; Dipyridamole; Humans; Methylation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentostatin; Superoxides | 1983 |
Further evidence for the purinergic inhibition of adrenergic neurotransmission in the rat portal vein.
Topics: Adenine; Adenosine; Aminophylline; Animals; Female; Male; Norepinephrine; Phenoxybenzamine; Portal Vein; Rats; Rats, Inbred Strains; Synaptic Transmission; Tetraethylammonium Compounds | 1981 |
Halogenated pyrrolopyrimidine analogues of adenosine from marine organisms: pharmacological activities and potent inhibition of adenosine kinase.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Adenosine; Adenosine Kinase; Adenylyl Cyclases; Animals; Brain; Bronchodilator Agents; Cardiovascular System; Central Nervous System; Guinea Pigs; In Vitro Techniques; Male; Marine Biology; Mice; Phosphotransferases; Rats; Ribonucleosides; Theophylline; Tubercidin | 1984 |
Capacity for energy metabolism in microvessels isolated from rat brain.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Cerebrovascular Circulation; Electron Transport Complex IV; Energy Metabolism; Microcirculation; Oxygen Consumption; Rats; Rats, Inbred Strains | 1984 |
Effect of hormones on adenine and adenosine metabolism in mammary gland in vitro.
Topics: Adenine; Adenosine; Animals; Female; Hydrocortisone; Insulin; Mammary Glands, Animal; Mice; Organ Culture Techniques; Phosphotransferases; Pregnancy; Prolactin | 1984 |
Characterization of purine nucleotide metabolism in primary rat cardiomyocyte cultures.
Topics: 5'-Nucleotidase; Adenine; Adenosine; AMP Deaminase; Animals; Carbon Radioisotopes; Cells, Cultured; Fibroblasts; Formates; Humans; Hypoxanthine; Hypoxanthines; Kinetics; Muscles; Myocardium; Nucleotidases; Purine Nucleotides; Rats; Rats, Inbred Strains; Skin; Tritium | 1984 |
The synergistic action of caffeine or adenosine on glucose stimulation of liver glycogen synthase phosphatase activity.
Topics: Adenine; Adenosine; Animals; Caffeine; Drug Synergism; Enzyme Activation; Glucose; Glycogen-Synthase-D Phosphatase; Liver; Phosphoprotein Phosphatases; Rats | 1984 |
Inhibition of equine S-adenohomocysteine hydrolase by 2'-deoxyadenosine.
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Animals; Deoxyadenosines; Horses; Hydrolases; Liver; S-Adenosylhomocysteine; Vidarabine | 1984 |
Cyclosporine-induced adenosine triphosphate depletion in murine T and B lymphocytes.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Animals; B-Lymphocytes; Cell Separation; Chromatography, High Pressure Liquid; Cyclosporins; Female; Fluorescent Antibody Technique; Mice; Mice, Inbred C57BL; Spleen; T-Lymphocytes | 1984 |
Purine-mediated growth inhibition caused by a pyrE mutation in Escherichia coli K-12.
Topics: Adenine; Adenosine; Drug Resistance, Microbial; Escherichia coli; Genes; Genes, Bacterial; Kinetics; Mutation; Orotate Phosphoribosyltransferase; Pentosyltransferases; Purines | 1984 |
The transfer of 5'-methylthioadenosine from B82 cells through the medium to CHW-1102 cells.
Topics: Adenine; Adenosine; Animals; Cell Communication; Cell Line; Cricetinae; Culture Media; Deoxyadenosines; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Mitoguazone; Purine-Nucleoside Phosphorylase; Thionucleosides | 1983 |
Specificity and control of uptake of purines and other compounds in Bacillus subtilis.
Topics: Adenine; Adenosine; Aminoisobutyric Acids; Bacillus subtilis; Biological Transport; Guanine; Guanosine; Guanosine Triphosphate; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; Methylglucosides; Methylglycosides; Purines; Spores, Bacterial; Uracil | 1983 |
Purine biosynthesis de novo in rat skeletal muscle.
Topics: Adenine; Adenosine; Animals; Azaserine; Cycloserine; Female; Formates; Glycine; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Male; Muscles; Purines; Rats; Rats, Inbred Strains; Serine | 1983 |
5'-Methylthioadenosine is the major source of adenine in human cells.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Cell Line; Cells, Cultured; Deoxyadenosines; Humans; Leukemia, Lymphoid; Purine-Nucleoside Phosphorylase; Thionucleosides | 1984 |
Partial methylation of two adjacent adenosines in ribosomes from Euglena gracilis chloroplasts suggests evolutionary loss of an intermediate stage in the methyl-transfer reaction.
Topics: Adenine; Adenosine; Biological Evolution; Chloroplasts; Cloacin; Escherichia coli; Euglena gracilis; Methylation; Methyltransferases; Ribosomes; RNA Processing, Post-Transcriptional; RNA, Ribosomal | 1984 |
Ethanol-induced activation of adenine nucleotide turnover. Evidence for a role of acetate.
Topics: Acetates; Acetic Acid; Adenine; Adenine Nucleotides; Adenosine; Adult; Carbon Radioisotopes; Ethanol; Humans; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; Time Factors; Xanthine; Xanthines | 1984 |
Effects of adenosine and adenine nucleotides on the atrioventricular node of isolated guinea pig hearts.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Aminophylline; Animals; Atrioventricular Node; Atropine; Dipyridamole; Dose-Response Relationship, Drug; Electrophysiology; Guinea Pigs; Heart Block; Heart Conduction System; In Vitro Techniques; Nucleosides; Time Factors | 1984 |
Correlations between phospholipid methylation and neuronal catecholamine transport.
Topics: Adenine; Adenosine; Animals; Biological Transport; Cerebral Cortex; Cytosol; Homocysteine; Kinetics; Male; Membrane Lipids; Methylation; Norepinephrine; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; Synaptosomes | 1984 |
A comparison of adenine and some derivatives on pig isolated tracheal muscle.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Airway Resistance; Animals; Carbachol; In Vitro Techniques; Swine; Trachea | 1983 |
Regulation of thymocyte proliferation by endogenous adenosine and adenosine deaminase.
Topics: Adenine; Adenosine; Adenosine Deaminase; Animals; Cells, Cultured; Dipyridamole; DNA; Guinea Pigs; Lymphocyte Activation; Nucleoside Deaminases; Phenylisopropyladenosine; T-Lymphocytes; Theophylline | 1983 |
Spectrophotometric studies of the interaction of S-adenosylhomocysteinase with adenosine, adenine and cordycepin.
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Animals; Binding, Competitive; Deoxyadenosines; Dimethyl Sulfoxide; Hydrolases; Liver; NAD; Protein Binding; Rats; Spectrophotometry; Spectrophotometry, Ultraviolet | 1984 |
Evidence for the conversion of adenosine to 2'-deoxycoformycin by Streptomyces antibioticus.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Carbon Radioisotopes; Chromatography, Thin Layer; Coformycin; Cytarabine; Glycine; Pentostatin; Ribonucleosides; Streptomyces | 1984 |
Selective inhibition of various mitogen responses in human lymphocytes.
Topics: Adenine; Adenosine; B-Lymphocytes; DNA Replication; Humans; Immunosuppressive Agents; Lymphocyte Activation; Mitogens; T-Lymphocytes | 1984 |
N6-Methyladenosine inhibition of hypoxanthine uptake by Chinese hamster ovary cells.
Topics: Adenine; Adenosine; Animals; Biological Transport; Cells, Cultured; Cricetinae; Cricetulus; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Kinetics | 1983 |
Sensitive and selective assay for adenosine using high-pressure liquid chromatography with fluorometry.
Topics: Adenine; Adenosine; Animals; Chromatography, High Pressure Liquid; Dogs; Myocardium; Spectrometry, Fluorescence | 1983 |
Influence of adenosine on the vascular responses to sympathetic nerve stimulation in the canine subcutaneous adipose tissue.
Topics: Adenine; Adenosine; Adipose Tissue; Animals; Body Temperature; Dipyridamole; Dogs; Electric Stimulation; Female; Homeostasis; Inosine; Norepinephrine; Propranolol; Regional Blood Flow; Sympathetic Nervous System; Theophylline; Vascular Resistance; Vasoconstriction | 1983 |
Metabolism and uptake of adenosine in rat isolated lung and its inhibition.
Topics: Adenine; Adenosine; Animals; Dipyridamole; Guinea Pigs; In Vitro Techniques; Lung; Male; Platelet Aggregation; Rats; Rats, Inbred Strains; Tritium | 1983 |
Relationship between adenylate cytokinin production and Ti plasmid of Agrobacterium tumefaciens.
Topics: Adenine; Adenosine; Cell Transformation, Neoplastic; Cytokinins; Isopentenyladenosine; Plant Growth Regulators; Plasmids; Rhizobium; Zeatin | 1983 |
Effect of intraventricular adenosine on food intake in rats.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Animals; Appetite; Dose-Response Relationship, Drug; Drinking Behavior; Feeding Behavior; Humans; Injections, Intraventricular; Male; Rats; Rats, Inbred Strains; Stereotyped Behavior | 1983 |
Adenosine as a mediator of postcontraction hyperemia in dog gracilis muscle.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Animals; Dipyridamole; Dogs; Electric Conductivity; Female; Male; Muscle Contraction; Muscles; Oxygen Consumption; Perfusion | 1984 |
Adenine nucleotide stimulation of Ca2+-induced Ca2+ release in sarcoplasmic reticulum.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Calcium; Kinetics; Muscles; Rabbits; Sarcoplasmic Reticulum; Structure-Activity Relationship | 1984 |
Absorption and metabolism of adenine, adenosine-5'-monophosphate, adenosine and hypoxanthine by the isolated vascularly perfused rat small intestine.
Topics: Absorption; Adenine; Adenosine; Adenosine Monophosphate; Animals; Carbon Radioisotopes; Hypoxanthine; Hypoxanthines; Intestine, Small; Male; Rats; Rats, Inbred Strains | 1984 |
Influence of dietary purines on allopurinol metabolism and allopurinol induced oroticaciduria.
Topics: Adenine; Adenosine; Allopurinol; Diet; Humans; Hypoxanthine; Hypoxanthines; Male; Orotic Acid; Purines | 1984 |
Substance rates of different steps of purine metabolism in normal and preserved red blood cells (RBC) studied in experiments simulating in vivo conditions.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Dialysis; Erythrocytes; Humans; Kinetics; Purine Nucleotides; Purines | 1984 |
Interaction among the distinct effects of adenine and guanine depletion in mouse lymphoma cells.
Topics: Adenine; Adenosine; Alanine; Animals; Antimetabolites, Antineoplastic; Cell Division; DNA Replication; Guanine; Kinetics; Lymphoma; Methylthioinosine; Mice; Mycophenolic Acid | 1984 |
The relationship between purines, pyrimidines, nucleosides, and glutamine for fibroblast cell proliferation.
Topics: Adenine; Adenosine; Animals; Cell Division; Cell Line; DNA; Fibroblasts; Glutamine; Hypoxanthine; Hypoxanthines; Inosine; Mice; Nucleosides; Purines; Pyrimidines | 1984 |
[Adenosine and its derivatives released by neocortex synaptosomes of the guinea pig].
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Cerebral Cortex; Guinea Pigs; Hypoxanthines; In Vitro Techniques; Inosine; Synaptosomes | 1980 |
Inactivation of S-adenosylhomocysteine hydrolase by 5'-deoxy-5'-methylthioadenosine.
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Deoxyadenosines; Erythrocytes; Humans; Hydrolases; In Vitro Techniques; Ribose; Thioglycosides; Thionucleosides | 1981 |
Dependence of adenine production upon polyamine synthesis in cultured human lymphoblasts.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Adenosylmethionine Decarboxylase; Cells, Cultured; Genetic Variation; Humans; Hypoxanthine Phosphoribosyltransferase; Leukemia, Lymphoid; Polyamines; Purine-Nucleoside Phosphorylase; Putrescine; Spermidine; Spermine; Spleen; Thionucleosides | 1981 |
Transmethylation reactions are required for initial morphologic and biochemical responses of human monocytes to chemoattractants.
Topics: Adenine; Adenosine; Arachidonic Acid; Arachidonic Acids; Chemical Phenomena; Chemistry; Chemoreceptor Cells; Chemotaxis, Leukocyte; Homocysteine; Humans; Kinetics; Lipid Metabolism; Methylation; Monocytes | 1981 |
Adenine and adenosine metabolizing enzymes in cell-free extracts from Euglena gracilis.
Topics: Acid Phosphatase; Adenine; Adenine Phosphoribosyltransferase; Adenosine; Adenosine Kinase; Aminohydrolases; Euglena gracilis; Kinetics; Purine-Nucleoside Phosphorylase; Thionucleosides | 1982 |
[Escherichia coli K-12 mutants assimilating adenine via a new metabolic pathway].
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Adenosine Monophosphate; Escherichia coli; Genes, Bacterial; Genotype; Mutation; Phenotype; Purine-Nucleoside Phosphorylase | 1982 |
Some adenine and adenosine methylene-bridged estrogens.
Topics: Adenine; Adenosine; Animals; Breast Neoplasms; Cell Line; Drug Evaluation, Preclinical; Estradiol Congeners; Female; Humans; Indicators and Reagents; Leukemia P388; Mice; Structure-Activity Relationship | 1983 |
Beneficial metabolic effect of nucleoside augmentation on reperfusion injury following cardioplegic arrest.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Animals; Coronary Circulation; Dogs; Heart Arrest, Induced; Myocardium; Phosphocreatine | 1983 |
Effects of hyperoxia on biochemical indexes of pig aortic endothelial function.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Aorta, Thoracic; Cells, Cultured; DNA; Endothelium; L-Lactate Dehydrogenase; Oxygen; Proteins; Rubidium; Swine; Time Factors | 1983 |
Simple separation of adenine and adenosyl-sulfur compounds by high-performance liquid chromatography.
Topics: Adenine; Adenosine; Animals; Chromatography, High Pressure Liquid; Deoxyadenosines; Male; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides | 1983 |
6-substituted purines: a novel class of inhibitors of endogenous protein degradation in isolated rat hepatocytes.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Liver; Lysosomes; Male; Mercaptopurine; Proteins; Purines; Puromycin Aminonucleoside; Rats; Rats, Inbred Strains | 1982 |
[Incorporation of adenine derivatives into the cells of Brevibacterium ammoniagenes ganA mutants producers of inosinic acid].
Topics: Adenine; Adenosine; Brevibacterium; Culture Media; Inosine Monophosphate; Inosine Nucleotides; Mutation; Selection, Genetic | 1982 |
Uptake and utilization of 5'-methylthioadenosine by cultured baby-hamster kidney cells.
Topics: Adenine; Adenosine; Animals; Cell Division; Cell Line; Cricetinae; Deoxyadenosines; Kidney; Thionucleosides; Tubercidin | 1982 |
Role of adenosine in signal transmission of tubuloglomerular feedback.
Topics: Adenine; Adenosine; Angiotensin II; Animals; Dipyridamole; Dogs; Feedback; Glomerular Filtration Rate; Hydrostatic Pressure; Kidney Glomerulus; Kidney Tubules; Vasoconstriction | 1982 |
Two T lymphocyte subpopulations isolated from human peripheral blood following "in vitro" treatment with adenosine.
Topics: Adenine; Adenosine; Adult; Animals; Humans; In Vitro Techniques; Phytohemagglutinins; Rosette Formation; Sheep; T-Lymphocytes; Theophylline | 1980 |
Adenosine stimulation of uphill adenine transport in L1210 leukemia cells. Evidence for a novel countertransport mechanism.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Biological Transport; Coformycin; Dipyridamole; Kinetics; Leukemia L1210; Mice; Mice, Inbred Strains; Pentostatin | 1981 |
Determination of ionization constants by paper electrophoresis.
Topics: Adenine; Adenine Nucleotides; Adenosine; Bacteriocins; Buffers; Deoxyadenosines; Electrophoresis, Paper; Hydrogen-Ion Concentration; Models, Chemical | 1981 |
Suppression of human lymphocyte DNA and protein synthesis in vitro by adenosine and eight modified adenine nucleosides in the presence or in the absence of adenosine deaminase inhibitors, 2'-deoxycoformycin (DCF) and erythro-9-(2-hydroxy-3-nonyl) adenine
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Blood Proteins; Coformycin; DNA; Humans; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Pentostatin; Phytohemagglutinins | 1982 |
S-Adenosylhomocysteine accumulation and selective cytotoxicity in cultured T- and B-lymphocytes.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosylhomocysteinase; B-Lymphocytes; Cell Division; Cells, Cultured; Deoxyadenosines; Homocysteine; Humans; Hydrolases; Nucleoside Deaminases; S-Adenosylhomocysteine; T-Lymphocytes | 1982 |
Renal handling of 2'-deoxyadenosine and adenosine in humans and mice.
Topics: Adenine; Adenosine; Animals; Blood Proteins; Child, Preschool; Chromatography, High Pressure Liquid; Coformycin; Creatinine; Deoxyadenosines; Humans; Infant; Kidney; Male; Mice; Pentostatin; Protein Binding; Species Specificity | 1982 |
Inactivation of liver S-adenosylhomocysteine hydrolase in vitro of rats treated with erythro-9-(2-hydroxynon-3-yl)adenine.
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Animals; Deoxyadenosines; Enzyme Activation; Female; Hydrolases; Kinetics; Liver; Rats; Rats, Inbred Strains; Temperature | 1982 |
Metabolism of adenosine and 2'-deoxy-adenosine by fetal mouse calvaria in culture.
Topics: Adenine; Adenosine; Animals; Bone and Bones; Culture Media; Deoxyadenosines; Dilazep; Dipyridamole; Hypoxanthine; Hypoxanthines; Inosine; Mice; Organ Culture Techniques | 1982 |
Purine base and nucleoside uptake in Plasmodium berghei and host erythrocytes.
Topics: Adenine; Adenosine; Animals; Biological Transport, Active; Diffusion; Erythrocytes; Hypoxanthines; Inosine; Kinetics; Male; Plasmodium berghei; Purine Nucleosides; Purines; Rats | 1980 |
Adenylate degradation in Escherichia coli. The role of AMP nucleosidase and properties of the purified enzyme.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Escherichia coli; Hypoxanthines; Inosine; Kinetics; Molecular Weight; Mutation; N-Glycosyl Hydrolases; Phosphates | 1980 |
Purine metabolism during continuous erythrocyte culture of human malaria parasites (P. falciparum).
Topics: Adenine; Adenosine; Adenosine Triphosphate; Carbon Radioisotopes; Erythrocytes; Guanine; Humans; Hypoxanthines; Plasmodium falciparum; Purines | 1981 |
Uridine and uracil transport in Escherichia coli and transport-deficient mutants.
Topics: Adenine; Adenosine; Biological Transport; Escherichia coli; Guanine; Hypoxanthines; Inosine; Kinetics; Mutation; Species Specificity; Thymine; Uracil; Uridine | 1981 |
S-adenosylhomocysteine hydrolase from rat liver.
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Animals; Chromatography, Affinity; Hydrolases; Hydrolysis; Kinetics; Liver; Molecular Weight; Rats; S-Adenosylhomocysteine | 1982 |
Improved functional recovery of ischemic myocardium by suppression of adenosine catabolism.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Heart Arrest, Induced; In Vitro Techniques; Male; Myocardium; Perfusion; Rats; Rats, Inbred Strains | 1982 |
Purine levels in the intact rat brain. Studies with an implanted perfused hollow fibre.
Topics: Adenine; Adenosine; Animals; Brain; Chromatography, High Pressure Liquid; Guanosine; Hypoxanthines; Inosine; Male; Purines; Rats; Rats, Inbred Strains | 1982 |
The influence of adenosine on the no-reflow phenomenon in anoxic and ischaemic hearts.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Coronary Circulation; Coronary Disease; Dilatation, Pathologic; Kinetics; Male; Oxygen; Perfusion; Rats; Rats, Inbred Strains | 1982 |
Inactivation of rat liver S-adenosylhomocysteinase by iodoacetamide.
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Amino Acids; Animals; Chemical Phenomena; Chemistry; Hydrolases; Iodoacetamide; Iodoacetates; Liver; NAD; Rats; Sulfhydryl Compounds | 1982 |
The specificity of purine base and nucleoside uptake in promastigotes of Leishmania braziliensis panamensis.
Topics: Adenine; Adenosine; Animals; Biological Transport; Hypoxanthines; Inosine; Kinetics; Leishmania; Purine Nucleosides; Purines | 1982 |
Effect of 9-beta-D-arabinofuranosyladenine and erythro-9-(2-hydroxy-3-nonyl) adenine on the metabolism of S-adenosylhomocysteine, S-adenosylmethionine, and adenosine in rat liver.
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Animals; Female; Homocysteine; Hydrolases; Liver; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Vidarabine | 1982 |
Role of transmethylation reactions in cellular motility and phagocytosis.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adult; Animals; Cell Movement; Chemotaxis, Leukocyte; Depression, Chemical; Guinea Pigs; Humans; In Vitro Techniques; Lactones; Macrophages; Methylation; Models, Biological; Monocytes; Peptides; Phagocytosis; Phospholipids; S-Adenosylhomocysteine; S-Adenosylmethionine | 1980 |
Irreversible inhibition of S-adenosylhomocysteine hydrolase by nucleoside analogs.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosylhomocysteinase; Animals; Cattle; Chemical Phenomena; Chemistry; Hydrolases; Kinetics; Liver; Nucleosides; Structure-Activity Relationship; Vidarabine | 1981 |
Effect of 5'-methylthioadenosine on in vivo methyl esterification of human erythrocyte membrane proteins.
Topics: Adenine; Adenosine; Deoxyadenosines; Erythrocyte Membrane; Erythrocytes; Humans; Membrane Proteins; Methylation; Protein Methyltransferases; Protein O-Methyltransferase; Thionucleosides | 1981 |
Arginase inhibition.
Topics: Adenine; Adenosine; Animals; Arginase; Borates; Cattle; Cytidine; Cytosine; In Vitro Techniques; Liver; Ornithine | 1981 |
Structure and stability of complexes between poly-5-bromouridylic acid and 2,9-dimethyladenine or 2-methyladenosine.
Topics: Adenine; Adenosine; Chemical Phenomena; Chemistry; Circular Dichroism; Drug Stability; Molecular Conformation; Nucleic Acid Conformation; Poly U | 1980 |
Sensitive fluorimetry of adenine, its nucleosides and nucleotides.
Topics: Adenine; Adenine Nucleotides; Adenosine; Aldehydes; Indicators and Reagents; Microchemistry; Spectrometry, Fluorescence | 1980 |
[Possible regulatory role of 5'-methylthioadenosine on enzymatic methyl esterification of membrane protein].
Topics: Adenine; Adenosine; Deoxyadenosines; Erythrocytes; Humans; Membrane Proteins; Methylation; Protein O-Methyltransferase; S-Adenosylmethionine; Thionucleosides | 1981 |
Detection of proton-acceptor sites of hydrogen bonding in adenine X uracil base pairs by the use of 15N magnetic resonance.
Topics: Adenine; Adenosine; Base Composition; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; RNA, Transfer; Uracil | 1981 |
Role of adenosine in adipose tissue circulation.
Topics: Adenine; Adenosine; Adipose Tissue; Animals; Capillary Permeability; Dilazep; Dipyridamole; Dogs; Female; Inosine; Vascular Resistance; Vasodilator Agents | 1981 |
Release of radiolabelled adenosine derivatives from superfused synaptosome beds. Evidence for the output of adenosine.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Brain; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Potassium; Synaptosomes | 1981 |
Purine metabolism of human erythrocytes during storage and physiological conditions.
Topics: Adenine; Adenine Nucleotides; Adenosine; Blood Preservation; Dialysis; Erythrocyte Aging; Erythrocytes; Guanosine; Humans; Purines | 1981 |
The antilipolytic effect of endogenous and exogenous adenosine in canine adipose tissue in situ.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adipose Tissue; Animals; Dilazep; Dipyridamole; Dogs; Female; Lipolysis | 1981 |
Degradation of ATP by membrane-bound enzymatic activities in Dictyostelium discoideum monitored by high-pressure liquid chromatography.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Cell Membrane; Chromatography, High Pressure Liquid; Dictyostelium | 1980 |
Action of coenzyme A on adenine derivative receptors in isolated tissues.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Coenzyme A; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Muscle Contraction; Rabbits; Rats; Receptors, Drug; Theophylline | 1980 |
High affinity binding of 2-chloroadenosine to rat brain synaptic membranes.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Animals; Binding Sites; Brain; Rats; Synaptic Membranes | 1980 |
Metabolism of 1,N6-ethenoadenosine.
Topics: Adenine; Adenosine; Animals; Cells, Cultured; Leukemia L1210; Male; Mice; Rats; Sarcoma 180 | 1980 |
Adenosine metabolism and myocardial preservation. Consequences of adenosine catabolism on myocardial high-energy compounds and tissue blood flow.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Cardiopulmonary Bypass; Dogs; Heart Arrest, Induced; Myocardium; Phosphocreatine; Regional Blood Flow | 1980 |
Metabolism of adenine and adenosine in erythrocytes of patients with myotonic muscular dystrophy (MMD).
Topics: Adenine; Adenine Nucleotides; Adenosine; Biological Transport; Carbon Radioisotopes; Erythrocytes; Humans; Muscular Dystrophies | 1980 |
Uptake of purine bases and nucleosides in African trypanosomes.
Topics: Adenine; Adenosine; Animals; Dipyridamole; Guanosine; Hypoxanthines; Inosine; Kinetics; Purines; Trypanosoma; Trypanosoma brucei brucei | 1980 |
Newborn rabbit blood-brain barrier is selectively permeable and differs substantially from the adult.
Topics: Adenine; Adenosine; Aging; Amino Acids; Animals; Animals, Newborn; Blood-Brain Barrier; Brain; Carbohydrate Metabolism; Cerebrovascular Circulation; Choline; Rabbits | 1980 |
The metabolism of purine and pyrimidine nucleotides in rat cortex during insulin-induced hypoglycemia and recovery.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cerebral Cortex; Chromatography, High Pressure Liquid; Hypoglycemia; Insulin Coma; Male; Purine Nucleosides; Purine Nucleotides; Pyrimidine Nucleosides; Pyrimidine Nucleotides; Rats | 1981 |
Role of neutrophils in the development of preservation injury after small bowel preservation for transplantation in the rat.
Topics: Adenine; Adenosine; Allopurinol; Animals; Dextrans; Drug Combinations; Glutathione; Graft Survival; Hypertonic Solutions; Insulin; Intestine, Small; Male; Neutrophils; Organ Preservation; Organ Preservation Solutions; Raffinose; Rats; Rats, Sprague-Dawley; Transplantation, Heterotopic | 1993 |
Regulation of extracellular adenosine levels in the striatum of aging rats.
Topics: 2-Amino-5-phosphonovalerate; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Aging; Amino Acids; Animals; Corpus Striatum; Enzyme Inhibitors; Extracellular Space; Male; Microdialysis; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tubercidin | 1995 |
Hyperthyroidism increases adenosine transport and metabolism in the rat heart.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Kinase; Adenosylhomocysteinase; AMP Deaminase; Animals; Biological Transport; Body Weight; Disease Models, Animal; Heart; Hydrolases; Hyperthyroidism; Male; Myocardium; Nucleotidases; Organ Size; Phosphorylation; Purine-Nucleoside Phosphorylase; Rats; Thyroxine; Time Factors; Xanthine Oxidase | 1995 |
Characterization of the PGE receptor subtype mediating inhibition of superoxide production in human neutrophils.
Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Alprostadil; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Humans; Misoprostol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Prostaglandin E; Superoxides | 1995 |
Adenosine transformation by human red blood cell membranes.
Topics: Adenine; Adenosine; Erythrocyte Membrane; Humans; Piperazines | 1995 |
Involvement of adenosine deaminase and adenosine kinase in regulating extracellular adenosine concentration in rat hippocampal slices.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Basal Metabolism; Electric Stimulation; Hippocampus; In Vitro Techniques; Male; Purines; Rats; Tubercidin | 1995 |
Intermittent aortic crossclamping prevents cumulative adenosine triphosphate depletion, ventricular fibrillation, and dysfunction (stunning): is it preconditioning?
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Animals; Aorta; Constriction; Dogs; Inosine; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardial Stunning; Myocardium; Thioinosine; Ventricular Dysfunction, Left; Ventricular Fibrillation; Ventricular Function, Left | 1995 |
Accelerated purine base salvage--a possible cause of elevated nucleotide pool in the erythrocytes of patients with uraemia.
Topics: Adenine; Adenine Nucleotides; Adenosine; Erythrocyte Aging; Erythrocytes; Humans; Kidney Failure, Chronic; Purines; Reference Values; Uremia | 1994 |
Specific enzyme synthesizing adenosine from adenine and ribose-1-phosphate in invertebrates.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Adenosine Deaminase; Animals; Chromatography, DEAE-Cellulose; Chromatography, Gel; Fasciola hepatica; Hypoxanthine Phosphoribosyltransferase; Insecta; Invertebrates; Mollusca; Purine-Nucleoside Phosphorylase; Ribosemonophosphates; Snails; Trematoda | 1994 |
Synthesis of new N(6)-substituted 2-phenyl-8-azaadenosines. Their affinity for adenosine A1 and A2 receptors. A comparison with the corresponding 2-phenyl-9-benzyl-8-azaadenines. VI.
Topics: Adenine; Adenosine; Animals; Aza Compounds; Receptors, Purinergic P1; Sheep; Stereoisomerism; Structure-Activity Relationship | 1995 |
Interactions of nucleotides with fully unadenylylated glutamine synthetase from Salmonella typhimurium.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenylyl Imidodiphosphate; Amino Acid Sequence; Binding, Competitive; Crystallography, X-Ray; Fourier Analysis; Glutamate-Ammonia Ligase; Guanosine Diphosphate; Kinetics; Models, Molecular; Salmonella typhimurium | 1994 |
Induction of polyploidy in human lymphocytes in vitro by excess adenine, but not by adenosine.
Topics: Adenine; Adenosine; Cell Count; Cells, Cultured; Chi-Square Distribution; Chromosome Aberrations; Chromosome Disorders; Dose-Response Relationship, Drug; Female; Humans; Male; Metaphase; Mitosis; Polyploidy; Sister Chromatid Exchange; T-Lymphocytes | 1995 |
Preparation and characterization of polyclonal and monoclonal antibodies specific for covalently linked DNA/RNA cross sections.
Topics: Adenine; Adenosine; Animals; Antibodies; Antibodies, Monoclonal; Antibody Specificity; Antigen-Antibody Reactions; Binding, Competitive; Enzyme-Linked Immunosorbent Assay; Hemocyanins; Mice; Mice, Inbred BALB C; Rabbits; Serum Albumin, Bovine; Thymidine; Uridine | 1994 |
Structure-activity relationships of 9-alkyladenine and ribose-modified adenosine derivatives at rat A3 adenosine receptors.
Topics: Adenine; Adenosine; Animals; CHO Cells; Cricetinae; Rats; Receptors, Purinergic P1; Ribose; Structure-Activity Relationship | 1995 |
Characterization of the reactive intermediates in laser flash photolysis of adenine, adenosine and dAMP using acetone as photosensitizer.
Topics: Acetone; Adenine; Adenosine; Deoxyadenine Nucleotides; Kinetics; Lasers; Molecular Structure; Photolysis; Photosensitizing Agents; Spectrophotometry | 1995 |
[Interaction of formaldehyde with nucleic acids and their structural components in the presence of amines. V. Isotopic exchange of hydrogen 3H---1H at the C8 atom of dATP, adenosine, adenine, guanosine, and poly(A)].
Topics: Adenine; Adenosine; Amines; Amino Acid Sequence; Deoxyadenine Nucleotides; Formaldehyde; Guanosine; Hydrogen; Isotopes; Kinetics; Molecular Sequence Data; Nucleic Acids; Poly A | 1994 |
Effect of N-0861, a selective adenosine A1 receptor antagonist, on pharmacologic stress imaging with adenosine.
Topics: Adenine; Adenosine; Animals; Coronary Circulation; Coronary Disease; Dogs; Exercise Test; Hemodynamics; Norbornanes; Purinergic P1 Receptor Antagonists; Radionuclide Imaging; Thallium Radioisotopes; Vasodilation | 1995 |
New directions in pharmacologic stress imaging.
Topics: Adenine; Adenosine; Animals; Coronary Circulation; Coronary Disease; Dogs; Hemodynamics; Norbornanes; Purinergic P1 Receptor Antagonists | 1995 |
Adenosine analogues prevent phorbol ester-induced PKC depletion in porcine coronary artery via A1 receptor.
Topics: Adenine; Adenosine; Animals; Coronary Vessels; Dose-Response Relationship, Drug; Endothelins; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norbornanes; Phenethylamines; Phorbol 12,13-Dibutyrate; Protein Kinase C; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Receptors, Purinergic P2; Swine | 1995 |
Reversal of methylmercaptopurine ribonucleoside cytotoxicity by purine ribonucleosides and adenine.
Topics: Adenine; Adenosine; Antineoplastic Agents; Cell Division; Cell Survival; Cells, Cultured; Guanosine; Humans; Inosine; Mercaptopurine; Methylthioinosine; Nucleosides; Nucleotides; Purine Nucleosides; Ribonucleosides; T-Lymphocytes; Thioinosine; Thionucleotides | 1995 |
Selective determination of adenine-containing compounds by capillary electrophoresis with laser-induced fluorescence detection.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Electrophoresis; Hot Temperature; Hydrogen-Ion Concentration; Lasers; Reproducibility of Results; Spectrometry, Fluorescence; Xenopus laevis | 1994 |
Conformationally locked nucleoside analogues. Synthesis of dideoxycarbocyclic nucleoside analogues structurally related to neplanocin C.
Topics: Adenine; Adenosine; Adenosine Deaminase; Antiviral Agents; Bridged Bicyclo Compounds; Chromatography, High Pressure Liquid; Computer Simulation; HIV; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Nucleic Acid Conformation; Nucleosides; Stereoisomerism; Structure-Activity Relationship; Temperature | 1994 |
Damage to uracil- and adenine-containing bases, nucleosides, nucleotides and polynucleotides: quantum yields on irradiation at 193 and 254 nm.
Topics: Adenine; Adenosine; Adenosine Monophosphate; DNA Damage; Dose-Response Relationship, Radiation; Lasers; Polydeoxyribonucleotides; Polyribonucleotides; Quantum Theory; Structure-Activity Relationship; Ultraviolet Rays; Uracil; Uridine; Uridine Monophosphate | 1994 |
2-Aryl-8-azaadenosines: structure-activity relationships in the binding with A1 and A2 receptors. A comparison with the corresponding 9-benzyl-8-azaadenines. III.
Topics: Adenine; Adenosine; Animals; Cerebral Cortex; In Vitro Techniques; Ligands; Membrane Proteins; Rats; Receptors, Purinergic P1; Sheep; Structure-Activity Relationship | 1994 |
Identification and functional characterization of A1 and A2 adenosine receptors in the rat vas deferens: a comparison with A1 receptors in guinea pig left atrium and A2 receptors in guinea pig aorta.
Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta; Guinea Pigs; Heart; In Vitro Techniques; Male; Norbornanes; Phenethylamines; Rats; Receptors, Purinergic P1; Theophylline; Vas Deferens; Xanthines | 1994 |
Cardiovascular effects of a non-xanthine-selective antagonist of the A1 adenosine receptor in the anaesthetised pig: pharmacological and therapeutic implications.
Topics: Adenine; Adenosine; Anesthesia; Animals; Atropine; Cardiovascular System; Coronary Vessels; Female; Heart; Male; Norbornanes; Propranolol; Purinergic P1 Receptor Antagonists; Regional Blood Flow; Swine; Theophylline | 1994 |
Nucleoside trapping during reperfusion prevents ventricular dysfunction, "stunning," in absence of adenosine. Possible separation between ischemic and reperfusion injury.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Affinity Labels; Animals; Biological Transport, Active; Dogs; Female; Inosine; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Stunning; Purinones; Random Allocation; Thioinosine; Ventricular Function, Left | 1994 |
A selective adenosine A1 receptor antagonist attenuates renal dysfunction during controlled hypotension with adenosine in rats.
Topics: Adenine; Adenosine; Animals; Blood Pressure; Hypotension, Controlled; Kidney; Male; Norbornanes; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley | 1994 |
Separation between ischemic and reperfusion injury by site specific entrapment of endogenous adenosine and inosine using NBMPR and EHNA.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Dogs; Female; Heart; Inosine; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Thioinosine; Ventricular Function, Left | 1994 |
Effect of the carbocyclic nucleoside analogue MDL 201,112 on inhibition of interferon-gamma-induced priming of Lewis (LEW/N) rat macrophages for enhanced respiratory burst and MHC class II Ia+ antigen expression.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Bordetella pertussis; Brain; Dipyridamole; Down-Regulation; Female; Histocompatibility Antigens Class II; Interferon-gamma; Kinetics; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Mycobacterium tuberculosis; Rats; Rats, Inbred Lew; Receptors, Purinergic P1; Receptors, Purinergic P2; Recombinant Proteins; Respiratory Burst; Stimulation, Chemical; Superoxides; Tumor Necrosis Factor-alpha; Zymosan | 1994 |
Adenosine is a key component in preservation of ischemically damaged canine pancreas by the two-layer cold storage method.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Cold Temperature; Dogs; Female; Graft Survival; Hypertonic Solutions; Hypoxanthine; Hypoxanthines; Inosine; Ischemia; Kinetics; Male; Organ Preservation; Pancreas; Pancreas Transplantation; Time Factors | 1994 |
Release and regulation of endogenous adenosine during hemorrhage.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Blood Pressure; Cats; Chromatography, High Pressure Liquid; Dilazep; Drug Interactions; Female; Hemorrhage; Male | 1994 |
Nucleoside-induced arteriolar constriction: a mast cell-dependent response.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Affinity Labels; Animals; Arterioles; Cricetinae; Dose-Response Relationship, Drug; In Vitro Techniques; Inosine; Male; Mast Cells; Mesocricetus; Methylene Blue; Mouth; Muscle, Smooth, Vascular; p-Methoxy-N-methylphenethylamine; Purinergic P1 Receptor Antagonists; Thioinosine; Vasoconstriction | 1994 |
Pulsed magnetic fields affect oscillations of the adenylate cyclase enzyme system in Dictyostelium discoideum, athermally.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenylyl Cyclases; Animals; Dictyostelium; Kinetics; Magnetics; Spores, Fungal; Time Factors | 1994 |
Effects of mutational loss of nucleoside kinases on deoxyadenosine 5'-phosphate/deoxyadenosine substrate cycle in cultured CEM and V79 cells.
Topics: Adamantane; Adenine; Adenosine; Adenosine Kinase; Animals; Cell Division; Cell Line; Cricetinae; Deoxyadenosines; Deoxycytidine; Deoxycytidine Kinase; Deoxyribonucleotides; DNA; Fibroblasts; Humans; Hypoxanthine; Hypoxanthines; Kinetics; Lymphocytes; Thymidine; Time Factors; Tritium | 1994 |
Purine nucleotide levels in host tissues of Ehrlich ascites tumor-bearing mice in different growth phases of the tumor.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Carcinoma, Ehrlich Tumor; Cell Division; Chromatography, High Pressure Liquid; Female; Guanine Nucleotides; Guanosine; Inosine; Kinetics; Liver; Mice; Mice, Inbred ICR; Muscles; Purine Nucleotides; Time Factors | 1993 |
Augmentation of endogenous adenosine attenuates myocardial 'stunning' independently of coronary flow or hemodynamic effects.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Coronary Circulation; Dogs; Heart; Hemodynamics; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Stunning; Nucleosides; Thioinosine | 1993 |
Purine release and inhibition of synaptic transmission during hypoxia and hypoglycemia in rat hippocampal slices.
Topics: Adenine; Adenosine; Animals; Brain Ischemia; Electric Stimulation; Electrophysiology; Evoked Potentials; Hippocampus; Hypoglycemia; Hypoxia, Brain; In Vitro Techniques; Male; Purines; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission | 1993 |
Interactions of adenosine A1 receptor-mediated renal vasoconstriction with endogenous nitric oxide and ANG II.
Topics: Adenine; Adenosine; Angiotensin II; Animals; Arginine; Arginine Vasopressin; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Imidazoles; Kidney; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Purinergic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Regional Blood Flow; Renal Circulation; Serotonin; Tetrazoles; Thromboxane A2; Vascular Resistance; Vasoconstriction | 1993 |
Adenophostins A and B: potent agonists of inositol-1,4,5-trisphosphate receptor produced by Penicillium brevicompactum. Taxonomy, fermentation, isolation, physico-chemical and biological properties.
Topics: Adenine; Adenosine; Animals; Calcium Channels; Chromatography, High Pressure Liquid; Fermentation; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Mice; Penicillium; Receptors, Cytoplasmic and Nuclear | 1993 |
Accumulation and metabolism of adenallene by murine leukemia L1210 cells.
Topics: Adenine; Adenosine; Animals; Antiviral Agents; Biological Transport; Biotransformation; Cytosine; Kinetics; Leukemia L1210; Mice; Temperature; Thymine; Tritium; Tumor Cells, Cultured | 1994 |
Adenosine and a related carbocyclic nucleoside analogue selectively inhibit tumor necrosis factor-alpha production and protect mice against endotoxin challenge.
Topics: Adenine; Adenosine; Animals; Cytokines; Endotoxins; Female; Interleukin-1; Macrophage Activation; Macrophages; Mice; Tumor Necrosis Factor-alpha | 1993 |
Position of cyclization in cyclic ADP-ribose.
Topics: Adenine; Adenosine; Adenosine Diphosphate Ribose; Cyclic ADP-Ribose; Hydrogen-Ion Concentration; Models, Chemical; Spectrophotometry, Ultraviolet | 1993 |
In vitro and in vivo pharmacological characterization of N6-cyclopentyl-9-methyladenine (N-0840): a selective, orally active A1 adenosine receptor antagonist.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Adenosine; Adenosine Deaminase; Administration, Oral; Animals; Cattle; Guinea Pigs; Heart Rate; In Vitro Techniques; Male; Purinergic Antagonists; Rabbits; Radioligand Assay; Rats; Vasodilator Agents | 1993 |
Activity-dependent release of endogenous adenosine modulates synaptic responses in the rat hippocampus.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Animals; Baclofen; Electric Stimulation; Electrophysiology; Evoked Potentials; Hippocampus; Male; Purinergic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Purinergic; Synapses; Theophylline | 1993 |
Arsenical-resistant trypanosomes lack an unusual adenosine transporter.
Topics: Adenine; Adenosine; Animals; Antiprotozoal Agents; Arsenicals; Biological Transport; Carrier Proteins; Drug Resistance; Inosine; Kinetics; Melarsoprol; Trypanosoma brucei brucei | 1993 |
Increases in interstitial adenosine and cerebral blood flow with inhibition of adenosine kinase and adenosine deaminase.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Brain; Cerebrovascular Circulation; Dialysis Solutions; Dose-Response Relationship, Drug; Extracellular Space; Hypoxanthine; Hypoxanthines; Inosine; Male; Rats; Rats, Wistar; Tubercidin | 1993 |
Changes in pial arteriolar diameter and CSF adenosine concentrations during hypoxia.
Topics: Adenine; Adenosine; Animals; Arterioles; Cerebrovascular Circulation; Dipyridamole; Hypoxanthine; Hypoxanthines; Hypoxia; Inosine; Male; Pia Mater; Rats; Rats, Sprague-Dawley; Vasodilation | 1993 |
Hepatic utilization of exogenous nucleotide precursors for restoration of ATP after cold ischemia in rats.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; Cold Temperature; Ischemia; Liver; Magnetic Resonance Spectroscopy; Male; Nucleotides; Rats; Rats, Sprague-Dawley | 1993 |
Effect of selective A1 adenosine receptor antagonism of postdefibrillation cardiovascular depression: evidence for an antiadrenergic role of endogenous adenosine.
Topics: Adenine; Adenosine; Animals; Electric Countershock; Female; Heart; Male; Myocardial Contraction; Norbornanes; Propranolol; Purinergic Antagonists; Receptors, Adrenergic; Swine | 1993 |
Endogenous adenosine, A1 adenosine receptor, and pertussis toxin sensitive guanine nucleotide binding protein mediate hypoxia induced AV nodal conduction block in guinea pig heart in vivo.
Topics: Adenine; Adenosine; Animals; Female; GTP-Binding Proteins; Guinea Pigs; Heart; Heart Block; Male; Myocardial Ischemia; Norbornanes; Pertussis Toxin; Purinergic Antagonists; Receptors, Purinergic; Virulence Factors, Bordetella | 1993 |
Adenosine increases lactate release and delays onset of contracture during global low flow ischaemia.
Topics: Adenine; Adenosine; Animals; Glucose; Lactates; Lactic Acid; Male; Myocardial Contraction; Myocardial Ischemia; Rats; Rats, Wistar; Xanthines | 1993 |
Effect of K+ depolarization, tetrodotoxin, and NMDA receptor inhibition on extracellular adenosine levels in rat striatum.
Topics: 2-Amino-5-phosphonovalerate; Adenine; Adenosine; Amino Acids; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dipyridamole; Male; Perfusion; Potassium; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 1993 |
(+-)-N6-endonorbornan-2-yl-9-methyladenine (N-0861) and its enantiomers: selective antagonists of A1-adenosine receptors in guinea pig isolated atria.
Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta; Drug Antagonism; Guinea Pigs; Heart; Heart Atria; In Vitro Techniques; Male; Muscle Relaxation; Norbornanes; Purinergic Antagonists; Stereoisomerism; Vasodilator Agents | 1993 |
2-Phenylethoxy-9-methyladenine: an adenosine receptor antagonist that discriminates between A2 adenosine receptors in the aorta and the coronary vessels from the guinea pig.
Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta; Coronary Vessels; Guinea Pigs; Heart Atria; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Purinergic Antagonists; Vasodilator Agents | 1993 |
[3H]adenosine transport in synaptoneurosomes of postmortem human brain.
Topics: Adenine; Adenosine; Aged; Biological Transport; Cadaver; Cerebral Cortex; Dilazep; Dipyridamole; Female; Humans; Kinetics; Male; Synaptosomes; Time Factors; Tritium; Tubercidin | 1993 |
Characterization of adenosine A2 receptors in bovine retinal membranes.
Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding Sites; Cattle; Receptors, Purinergic; Retina; Synaptic Membranes; Vasodilator Agents | 1993 |
Inhibition of hydroxyl radical production by lactobionate, adenine, and tempol.
Topics: Adenine; Adenosine; Antioxidants; Bicarbonates; Cardioplegic Solutions; Cyclic N-Oxides; Disaccharides; HEPES; Hydroxyl Radical; Kinetics; Phosphates; Spin Labels; Superoxides | 1995 |
Automated screening system for purine and pyrimidine metabolism disorders using high-performance liquid chromatography.
Topics: Adenine; Adenosine; Autoanalysis; Chromatography, High Pressure Liquid; Humans; Orotic Acid; Pseudouridine; Purine-Pyrimidine Metabolism, Inborn Errors; Uracil; Xanthine; Xanthines | 1995 |
N(6) or N(9) substituted 2-phenyl-8-azaadenines: affinity for A1 adenosine receptors. VII.
Topics: Adenine; Adenosine; Animals; Aza Compounds; Cerebral Cortex; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Kinetics; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Muscle, Smooth; Myocardial Contraction; Neostriatum; Rats; Receptors, Purinergic P1; Sheep; Thermodynamics; Vasodilator Agents | 1995 |
Activities associated with the presence of ribosome-inactivating proteins increase in senescent and stressed leaves.
Topics: Adenine; Adenosine; Cell Extracts; DNA; Hot Temperature; Osmotic Pressure; Plant Leaves; Plant Proteins; Plants; Protein Biosynthesis; Protein Synthesis Inhibitors | 1996 |
Smooth muscle cell-derived adenosine inhibits cell growth.
Topics: Adenine; Adenosine; Animals; Cell Division; Cells, Cultured; Dipyridamole; DNA Replication; Enzyme Inhibitors; Male; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley | 1996 |
Selective attenuation by N-0861 (N6-endonorboran-2-yl-9-methyladenine) of cardiac A1 adenosine receptor-mediated effects in humans.
Topics: Adenine; Adenosine; Aged; Coronary Circulation; Dose-Response Relationship, Drug; Female; Heart; Humans; Male; Middle Aged; Norbornanes; Pain; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1 | 1996 |
Release of oxygen metabolites from chemoattractant-stimulated neutrophils is inhibited by resting platelets: role of extracellular adenosine and actin polymerization.
Topics: Actin Cytoskeleton; Actins; Adenine; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Biological Factors; Blood Platelets; Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Culture Media, Conditioned; Cytochalasin B; Humans; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Purinergic P1 Receptor Antagonists; Reactive Oxygen Species; Receptors, Purinergic P1; Respiratory Burst; Theophylline | 1996 |
Antagonistic effect of nucleic acid precursors on the anticoccidial activity of 6-azauracil.
Topics: Adenine; Adenosine; Animals; Chickens; Coccidiosis; Coccidiostats; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance; Eimeria; Food, Fortified; Male; Nucleic Acid Precursors; Orotic Acid; Poultry Diseases; Uracil; Uridine | 1996 |
Carbocyclic nucleosides as inhibitors of human tumor necrosis factor-alpha production: effects of the stereoisomers of (3-hydroxycyclopentyl)adenines.
Topics: Adenine; Adenosine; Animals; Cyclopentanes; Galactosamine; Humans; Interleukin-1; Interleukin-6; Lipopolysaccharides; Macrophages; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; Stereoisomerism; Tumor Necrosis Factor-alpha | 1996 |
Role of adenine nucleotides in the activation of microsomal cholesterol ester hydrolase by fructose or adenosine in rat hepatocytes.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; AMP Deaminase; Animals; Cells, Cultured; Enzyme Activation; Female; Fructose; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Sterol Esterase | 1996 |
Characterization of inhibitor-sensitive and -resistant adenosine transporters in cultured human fetal astrocytes.
Topics: Adenine; Adenosine; Affinity Labels; Astrocytes; Biological Transport; Carrier Proteins; Cells, Cultured; Dilazep; Dipyridamole; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fetus; Humans; Kinetics; Membrane Proteins; Nucleoside Transport Proteins; Thioinosine; Tritium; Tubercidin; Vasodilator Agents | 1996 |
Adenosine uptake and deamination regulate tonic A2a receptor facilitation of evoked [3H]acetylcholine release from the rat motor nerve terminals.
Topics: Acetylcholine; Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Affinity Labels; Animals; Deamination; Diaphragm; Electric Stimulation; Enzyme Inhibitors; Female; In Vitro Techniques; Male; Motor Neurons; Phrenic Nerve; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, Purinergic P1; Thioinosine | 1996 |
Endogenous adenosine increases O2 utilisation efficiency in isoprenaline-stimulated canine myocardium.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adrenergic beta-Agonists; Animals; Dogs; Hypoxia; Isoproterenol; Lactic Acid; Myocardial Contraction; Myocardial Ischemia; Myocardium; Oxygen; Oxygen Consumption; Perfusion; Stimulation, Chemical | 1996 |
Involvement of adenosine in retinal ischemia. Studies on the rat.
Topics: Adenine; Adenosine; Adenosine Deaminase; Animals; Calbindin 2; Dyneins; Electroretinography; Enzyme Inhibitors; Eye Proteins; Fluorescent Antibody Technique, Indirect; Glial Fibrillary Acidic Protein; Ischemia; Phenylisopropyladenosine; Rats; Receptors, Purinergic P1; Reperfusion Injury; Retinal Vessels; S100 Calcium Binding Protein G | 1996 |
Neurite outgrowth in PC12 cells is enhanced by guanosine through both cAMP-dependent and -independent mechanisms.
Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Animals; Antineoplastic Agents; Colforsin; Cyclic AMP; Enzyme Inhibitors; Guanosine; Guanosine Triphosphate; Nerve Growth Factors; Neurites; PC12 Cells; Rats | 1996 |
Interruption of Escherichia coli heat-stable enterotoxin-induced guanylyl cyclase signaling and associated chloride current in human intestinal cells by 2-chloroadenosine.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Bacterial Toxins; Caco-2 Cells; Chloride Channels; Enterotoxins; Enzyme Inhibitors; Escherichia coli Proteins; Guanylate Cyclase; Humans; Models, Biological; Pentostatin; Purinergic P1 Receptor Agonists; Signal Transduction | 1997 |
Adenosine increases the cAMP content of the rat carotid body in vitro.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenine; Adenosine; Animals; Carotid Body; Cyclic AMP; Male; Nerve Tissue Proteins; Perfusion; Phenethylamines; Rats; Rats, Wistar; Receptors, Purinergic P1; Second Messenger Systems | 1996 |
Crystal structure of a polyhistidine-tagged recombinant catalytic subunit of cAMP-dependent protein kinase complexed with the peptide inhibitor PKI(5-24) and adenosine.
Topics: Adenine; Adenosine; Amino Acid Sequence; Animals; Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; Cyclic AMP-Dependent Protein Kinases; Histidine; Mice; Molecular Sequence Data; Peptide Fragments; Peptides; Phosphates; Protein Conformation; Protein Kinase Inhibitors; Recombinant Proteins; Ribose | 1997 |
Carbocyclic oxetanocins lacking the C-3' methylene.
Topics: Adenine; Adenosine; Animals; Antiviral Agents; Cells, Cultured; Giant Cells; Guanine; Herpesvirus 1, Human; Herpesvirus 3, Human; HIV-1; HIV-2; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Viruses | 1997 |
Adenosine metabolism during phorbol myristate acetate-mediated induction of HL-60 cell differentiation: changes in expression pattern of adenosine kinase, adenosine deaminase, and 5'-nucleotidase.
Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Deaminase; Adenosine Kinase; B-Lymphocytes; Cell Differentiation; Extracellular Space; Gene Expression Regulation, Enzymologic; HL-60 Cells; Humans; Hypoxanthine; Purines; RNA, Messenger; Stress, Physiological; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1997 |
Hypoxanthine uptake at the fetal side of human placenta proceeds through a nucleobase-preferring carrier and a non-saturable process.
Topics: Adenine; Adenosine; Biological Transport; Blood Flow Velocity; Female; Fetus; Guanine; Humans; Hypoxanthine; Papaverine; Placenta; Pregnancy; Sodium; Tritium | 1997 |
Endogenous adenosine facilitates neurotransmission via A2A adenosine receptors in the rat superior colliculus in vivo.
Topics: Adenine; Adenosine; Animals; Electrophysiology; Enzyme Inhibitors; Purinergic Antagonists; Purines; Rats; Receptors, Purinergic P1; RNA, Messenger; Superior Colliculi; Synaptic Transmission; Xanthines | 1997 |
Trypanosoma brucei: lack of cross-resistance to melarsoprol in vitro by cymelarsan-resistant parasites.
Topics: Adenine; Adenosine; Animals; Arsenicals; Diminazene; Dose-Response Relationship, Drug; Drug Resistance; Enzyme Inhibitors; Female; Inosine; Melarsoprol; Mice; Pentamidine; Trypanocidal Agents; Trypanosoma brucei brucei | 1997 |
Neurotoxicity in organotypic hippocampal slices mediated by adenosine analogues and nitric oxide.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Animals, Newborn; Brain Ischemia; Cell Survival; Enzyme Inhibitors; Hippocampus; Neurons; Neurotoxins; Nitric Oxide; Organ Culture Techniques; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theobromine; Theophylline; Xanthines | 1997 |
Evidence against a major role of adenosine in oxygen-dependent regulation of erythropoietin in rats.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Animals; Antihypertensive Agents; Carbon Monoxide; Dipyridamole; Diuretics; Drug Synergism; Enzyme Inhibitors; Erythropoietin; Gene Expression; Hypoxia; Kidney; Male; Oxygen; Phenethylamines; Phosphodiesterase Inhibitors; Piperazines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; RNA, Messenger; Theophylline; Vasodilator Agents; Xanthines | 1997 |
Adenosine triphosphate degradation products after oxidative stress and metabolic dysfunction in cultured retinal cells.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Cell Hypoxia; Cells, Cultured; Chick Embryo; Enzyme Inhibitors; Glucose; Hypoxanthine; Inosine; Iodoacetates; Iodoacetic Acid; Ischemia; Kinetics; Oligomycins; Oxidative Stress; Retina; Thioinosine | 1997 |
Ischemic preconditioning prevents the impairment of hypoxic coronary vasodilatation caused by ischemia/reperfusion: role of adenosine A1/A3 and bradykinin B2 receptor activation.
Topics: Adenine; Adenosine; Animals; Bradykinin; Bradykinin Receptor Antagonists; Coronary Vessels; Guinea Pigs; Hypoxia; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Male; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Synthase; Norbornanes; Receptor, Adenosine A3; Receptor, Bradykinin B2; Receptors, Bradykinin; Receptors, Purinergic P1; Vasodilation | 1997 |
Hydrolysis of extracellular adenine nucleotides by equine epidydimal spermatozoa.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Apyrase; Epididymis; Horses; Hydrolysis; Kinetics; Male; Nucleotidases; Nucleotides; Spermatozoa; Time Factors | 1997 |
Canine mast cell adenosine receptors: cloning and expression of the A3 receptor and evidence that degranulation is mediated by the A2B receptor.
Topics: Adenine; Adenosine; Amino Acid Sequence; Animals; Base Sequence; beta-N-Acetylhexosaminidases; Calcium; Chlorocebus aethiops; COS Cells; Dinucleoside Phosphates; DNA, Complementary; Dogs; Mast Cells; Mast-Cell Sarcoma; Molecular Sequence Data; Neoplasm Proteins; Norbornanes; Receptor, Adenosine A3; Receptors, Purinergic P1; RNA, Messenger; Sequence Alignment; Sequence Homology, Amino Acid; Xanthines | 1997 |
Exogenous and endogenous adenosine inhibits fetal calf serum-induced growth of rat cardiac fibroblasts: role of A2B receptors.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Adenosine-5'-(N-ethylcarboxamide); Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Cattle; Cell Division; Culture Media; Dipyridamole; DNA Replication; Enzyme Inhibitors; Fibroblasts; Heart; Male; Myocardium; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Tubercidin; Xanthines | 1997 |
Expansion of the cellular content of ribonucleoside triphosphates induces cell shrinkage and KCl loss in Ehrlich ascites tumor cells and in Chinese hamster ovary cells.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Carcinoma, Ehrlich Tumor; Chloride Channels; Chlorides; CHO Cells; Cricetinae; Guanine; Guanosine; Guanosine Triphosphate; Kinetics; Mice; Potassium Channels; Potassium Chloride; Purines; Ribonucleotides; Tumor Cells, Cultured | 1997 |
Inosine binds to A3 adenosine receptors and stimulates mast cell degranulation.
Topics: Adenine; Adenosine; Animals; Arterioles; Binding, Competitive; Cell Degranulation; Cricetinae; Guinea Pigs; Inosine; Iodine Radioisotopes; Iodobenzenes; Lung; Mast Cells; Norbornanes; Rats; Receptor, Adenosine A3; Receptors, Purinergic P1; Recombinant Fusion Proteins; Transfection; Tumor Cells, Cultured | 1997 |
Regulation of adenosine concentration and cytoprotective effects of novel reversible adenosine deaminase inhibitors.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Astrocytoma; Cattle; Cytoprotection; Endothelium, Vascular; Enzyme Inhibitors; Hippocampus; Humans; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured | 1997 |
Three-minute G + A specific reaction for DNA sequencing.
Topics: Adenine; Adenosine; Deoxyadenosines; DNA; Formamides; Guanosine; Guanosine Triphosphate; Sequence Analysis, DNA | 1998 |
Cyclic AMP-adenosine pathway induces nitric oxide synthesis in aortic smooth muscle cells.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Animals; Aorta, Thoracic; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytosol; Dideoxyadenosine; Enzyme Inhibitors; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Signal Transduction; Thionucleotides | 1998 |
Adenosine inhibits growth of human aortic smooth muscle cells via A2B receptors.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adult; Animals; Aorta, Thoracic; Cell Division; Cells, Cultured; Collagen; Dipyridamole; DNA; Humans; Kinetics; Male; Muscle, Smooth, Vascular; Phenethylamines; Purinergic P1 Receptor Antagonists; Rats; Receptor, Adenosine A2B; Receptors, Purinergic P1; Thymidine; Xanthines | 1998 |
Probing the active site of adenosine deaminase by a pH responsive fluorescent competitive inhibitor.
Topics: Adenine; Adenosine; Adenosine Deaminase; Animals; Binding Sites; Binding, Competitive; Catalysis; Cattle; Enzyme Inhibitors; Fluorescence Polarization; Fluorescent Dyes; Hydrogen-Ion Concentration; Intestines; Kinetics; Molecular Structure; Pentostatin; Protein Binding; Spectrometry, Fluorescence; Spectrophotometry | 1998 |
[Effects of adenosine and adenine on cold acclimation in mice].
Topics: Acclimatization; Adenine; Adenosine; Adipose Tissue, Brown; Animals; Blood Glucose; Body Temperature; Body Weight; Cold Temperature; Drinking; Eating; Fatty Acids, Nonesterified; Male; Mice; Mice, Inbred Strains; Organ Size; Rectum | 1997 |
Adenine/ribose supply increases adenosine production and protects ATP pool in adenosine kinase-inhibited cardiac cells.
Topics: Adenine; Adenosine; Adenosine Kinase; Adenosine Triphosphate; Animals; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Heart; In Vitro Techniques; Kinetics; Male; Myocardium; Purines; Rats; Rats, Sprague-Dawley; Ribose; Tubercidin; Uridine | 1998 |
The levels of adenosine and its metabolites in the guinea pig and rat brain during complete ischemia-in vivo study.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Brain; Brain Chemistry; Brain Ischemia; Chromatography, High Pressure Liquid; Dyneins; Enzyme Inhibitors; Guinea Pigs; Hypoxanthine; Inosine; Male; Microwaves; Rats; Rats, Wistar; Spectrophotometry, Ultraviolet; Tissue Fixation | 1998 |
The effects of adenosine on the energy metabolism of the reperfused intestine in rats.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; Energy Metabolism; Ischemia; Jejunum; Lipid Peroxidation; Male; Mesenteric Arteries; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Thiobarbituric Acid Reactive Substances | 1998 |
Dual cardiac microdialysis to assess drug-induced changes in interstitial purine metabolites: adenosine deaminase inhibition versus adenosine kinase inhibition.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Chromatography, High Pressure Liquid; Extracellular Space; Hypoxanthine; Inosine; Male; Microdialysis; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Rabbits; Tubercidin | 1998 |
Differential cardioprotection with selective inhibitors of adenosine metabolism and transport: role of purine release in ischemic and reperfusion injury.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Biological Transport; Carrier Proteins; Dogs; Enzyme Inhibitors; Membrane Proteins; Models, Cardiovascular; Myocardial Ischemia; Myocardial Reperfusion Injury; Nucleoside Transport Proteins; Purines; Thioinosine | 1998 |
Effects of nucleoside transport inhibitors and adenine/ribose supply on ATP concentration and adenosine production in cardiac myocytes.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Biological Transport; Carrier Proteins; Dipyridamole; Enzyme Inhibitors; Membrane Proteins; Myocardium; NAD; Nucleoside Transport Proteins; Rats; Rats, Sprague-Dawley; Ribose; Thioinosine | 1998 |
[Deamination of adenine and adenosine in staphylococci].
Topics: Adenine; Adenosine; Adenosine Deaminase; Ammonia; Animals; Chromatography, High Pressure Liquid; Deamination; Humans; Species Specificity; Staphylococcus | 1997 |
Structure of DNA containing aristeromycin analog.
Topics: Adenine; Adenosine; Base Sequence; Calorimetry; Cyclopentanes; DNA; Nucleic Acid Denaturation; Oligodeoxyribonucleotides; Thermodynamics | 1997 |
Inhibition of adenosine deaminase by erythro-9-(2-hydroxy-3-nonyl)adenine (EHNA) mimics the effect of inescapable shock on escape learning in rats.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Analysis of Variance; Animals; Caffeine; Central Nervous System Stimulants; Electroshock; Enzyme Inhibitors; Escape Reaction; Fear; Helplessness, Learned; Male; Neural Inhibition; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Reaction Time; Restraint, Physical; Stress, Psychological | 1998 |
Effects of nucleoside transport inhibitors and adenine/ribose on ATP concentration and adenosine production in cardiac myocytes.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Animals; Biological Transport; Cells, Cultured; Dipyridamole; Heart; Myocardium; Rats; Rats, Sprague-Dawley; Thioinosine | 1998 |
Endothelial purine metabolism and reperfusion injury.
Topics: Adenine; Adenosine; Benzene Derivatives; Cells, Cultured; Endothelium, Vascular; Humans; Hydrogen Peroxide; Hypoxanthine; Kinetics; Oxidants; Phosphocreatine; Purines; Reperfusion Injury; Umbilical Veins | 1998 |
Effects of adenine/ribose supply on adenosine production and ATP concentration in adenosine kinase inhibited cardiac cells.
Topics: Adenine; Adenosine; Adenosine Kinase; Adenosine Triphosphate; Animals; Cells, Cultured; Endothelium, Vascular; Heart; Kinetics; Myocardium; Rats; Rats, Sprague-Dawley; Ribose | 1998 |
Effects of dipyridamole and adenine/ribose on ATP concentration and adenosine production in cardiac myocytes.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Cardiomyopathy, Dilated; Cardiomyopathy, Hypertrophic; Dipyridamole; Energy Metabolism; Guanine Nucleotides; Heart Transplantation; Heart-Lung Transplantation; Humans; Myocardium; NAD; Ribose | 1998 |
Evaluation of adenine concentration in plasma of patients with renal failure using improved ultrafiltration technique.
Topics: Adenine; Adenosine; Chromatography, High Pressure Liquid; Humans; Kidney Failure, Chronic; Reference Values; Reproducibility of Results; Ultrafiltration | 1998 |
Effects of adenosine deaminase inhibition on blood pressure in old spontaneously hypertensive rats.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Aging; Animals; Blood Pressure; Enzyme Inhibitors; Hemodynamics; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Xanthines | 1998 |
Study of cytokinin metabolism using HPLC with radioisotope detection.
Topics: Adenine; Adenosine; Benzyl Compounds; Chromatography, High Pressure Liquid; Kinetin; Purines; Radiometry; Reproducibility of Results; Triticum; Tritium | 1998 |
Restoring adenine nucleotides in a brain slice model of cerebral reperfusion.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Animals; Carbon Dioxide; Glucose; Hippocampus; In Vitro Techniques; Ischemic Attack, Transient; Kinetics; Male; Models, Biological; Nitrogen; Oxygen; Rats; Rats, Sprague-Dawley; Reperfusion | 1998 |
Synthesis, antiviral and cytostatic activities of carbocyclic nucleosides incorporating a modified cyclopentane ring. Part 2: Adenosine and uridine analogues.
Topics: Adenine; Adenosine; Animals; Antiviral Agents; Cell Division; Cyclopentanes; Models, Chemical; Tumor Cells, Cultured; Uracil; Uridine | 1998 |
Modulation of adenosine effects in attenuation of ischemia and reperfusion injury in rat heart.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Enzyme Inhibitors; Heart; Heart Rate; In Vitro Techniques; Isoenzymes; L-Lactate Dehydrogenase; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Organophosphates; Purines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Stroke Volume; Superoxides; Thioinosine; Xanthine Oxidase | 1998 |
Involvement of adenosine in vanadate-stimulated release of lipoprotein lipase activity.
Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenylyl Cyclases; Adipose Tissue; Animals; Enzyme Inhibitors; Extracellular Space; In Vitro Techniques; Lipoprotein Lipase; Male; Rats; Rats, Wistar; Stimulation, Chemical; Vanadates | 1998 |
Evidence that IgE receptor stimulation increases adenosine release from rat basophilic leukaemia (RBL-2H3) cells.
Topics: Adenine; Adenosine; Animals; beta-N-Acetylhexosaminidases; Cytoplasmic Granules; Leukemia, Basophilic, Acute; Mast Cells; Purinergic P1 Receptor Agonists; Rats; Receptor, Adenosine A3; Receptors, IgE; Serotonin; Tubercidin; Tumor Cells, Cultured | 1998 |
Metabolic regulation of endogenous adenosine release from single neurons.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Dinucleoside Phosphates; Drug Administration Routes; Electric Stimulation; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Models, Biological; Neurons; Patch-Clamp Techniques; Purinergic P1 Receptor Antagonists; Pyramidal Cells; Rats; Theophylline; Tubercidin | 1998 |
Inhibition studies on membrane adenosine deaminase from human placenta.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Cell Membrane; Chromatography, Affinity; Erythrocytes; Female; Humans; Placenta; Pregnancy; Ultracentrifugation | 1998 |
Adenosine inhibits collagen and total protein synthesis in vascular smooth muscle cells.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Animals; Aorta, Abdominal; Cells, Cultured; Collagen; Cyclic AMP; Dipyridamole; Kinetics; Leucine; Male; Muscle, Smooth, Vascular; Proline; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Xanthines | 1999 |
Processing of adenosine receptor agonists in rat and human whole blood.
Topics: Adenine; Adenosine; Adenosine Kinase; Aminohydrolases; Animals; Blood; Deoxyadenosines; Enzyme Inhibitors; Humans; Purinergic P1 Receptor Agonists; Rats; Thioinosine | 1998 |
Endogenous adenosine reduces the occurrence of ischemia-induced ventricular fibrillation in rat heart.
Topics: Adenine; Adenosine; Aminoimidazole Carboxamide; Animals; Caffeine; Creatine Kinase; Electrocardiography; Enzyme Inhibitors; Hypoxanthine; Inosine; Male; Myocardial Ischemia; Myocardium; Perfusion; Rats; Rats, Wistar; Reperfusion Injury; Ribonucleosides; Theophylline; Thioinosine; Thiophenes; Time Factors; Ventricular Fibrillation; Xanthines | 1999 |
Involvement of the adenosine neuromodulatory system in the benzodiazepine-induced depression of excitatory synaptic transmissions in rat hippocampal neurons in vitro.
Topics: Adenine; Adenosine; Aminophylline; Animals; Benzodiazepines; Bicuculline; Dentate Gyrus; Dipyridamole; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; GABA Antagonists; Hippocampus; Midazolam; Neurons; Neurotransmitter Agents; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Synaptic Transmission | 1999 |
Quantification of extracellular and intracellular adenosine production: understanding the transmembranous concentration gradient.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Biological Transport; Bradykinin; Coronary Circulation; Cytosol; Depression, Chemical; Dipyridamole; Drug Synergism; Enzyme Inhibitors; Extracellular Space; Guinea Pigs; Heart; Models, Biological; Myocardium; Osmolar Concentration; Oxygen; Oxygen Consumption; Piperazines; Thioinosine; Tubercidin | 1999 |
Propentofylline protects neurons in culture from death triggered by macrophage or microglial secretory products.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Cell Death; Cell Hypoxia; Cell Survival; Cells, Cultured; Culture Media, Conditioned; Fetus; Hippocampus; Macrophages, Peritoneal; Mice; Microglia; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Xanthines | 1999 |
The prebiotic synthesis of modified purines and their potential role in the RNA world.
Topics: Adenine; Adenosine; Amines; Amino Acids; Guanine; Hydrogen-Ion Concentration; Hydrolysis; Hypoxanthine; Hypoxanthines; Purines; RNA; Temperature | 1999 |
Adenine-nucleotide binding sites on the inositol 1,4,5-trisphosphate receptor bind caffeine, but not adenophostin A or cyclic ADP-ribose.
Topics: Adenine; Adenosine; Adenosine Diphosphate Ribose; Animals; Binding Sites; Caffeine; Calcium; Calcium Channels; Cyclic ADP-Ribose; Dose-Response Relationship, Drug; Inhibitory Concentration 50; Inositol 1,4,5-Trisphosphate Receptors; Mice; Models, Genetic; Protein Binding; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Time Factors | 1999 |
Is the growth of brown adipocytes necessary for cold acclimation in mice?
Topics: Acclimatization; Adenine; Adenosine; Adipocytes; Adipose Tissue, Brown; Animals; Blood Glucose; Butyrates; Cardiovascular Agents; Cold Temperature; Drinking; Eating; Fatty Acids, Nonesterified; Male; Mice; Organ Size; Weight Gain | 1999 |
Further evidence for the role of adenosine in hypercapnia/acidosis-evoked coronary flow regulation.
Topics: Acidosis; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Carbon Dioxide; Coronary Circulation; Enzyme Inhibitors; Heart Rate; Hypercapnia; Male; Myocardial Contraction; Rats; Rats, Sprague-Dawley; Time Factors; Tubercidin; Vasodilator Agents | 1999 |
The anticonvulsant BW534U87 depresses epileptiform activity in rat hippocampal slices by an adenosine-dependent mechanism and through inhibition of voltage-gated Na+ channels.
Topics: Action Potentials; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Anticonvulsants; Brain Chemistry; CHO Cells; Cricetinae; Electrophysiology; Enzyme Inhibitors; Epilepsy; Female; Hippocampus; In Vitro Techniques; Ion Channel Gating; Magnesium; Male; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sodium Channels; Triazoles | 1999 |
Effects of allopurinol, erythro-9-(2-hydroxy-3-nonyl)adenine and S-(4-nitrobenzyl)-6-thioinosine on the degradation of adenosine 5'-triphosphate in the rat colon muscularis mucosae.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Allopurinol; Animals; Colon; Enzyme Inhibitors; Half-Life; In Vitro Techniques; Intestinal Mucosa; Muscle, Smooth; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Thioinosine | 1999 |
A(2B) receptors mediate antimitogenesis in vascular smooth muscle cells.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Kinase; Adenosine-5'-(N-ethylcarboxamide); Animals; Anticoagulants; Antihypertensive Agents; Aorta, Abdominal; Becaplermin; Cell Division; Dinucleoside Phosphates; Enzyme Inhibitors; Hyperplasia; Male; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Oligonucleotides, Antisense; Phenethylamines; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-2; Thymidine; Tritium; Tubercidin; Vasodilator Agents; Xanthines | 2000 |
Age-related changes in A(1)-adenosine receptor-mediated bradycardia.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Aging; Animals; Bradycardia; Enzyme Inhibitors; Male; Rats; Rats, Wistar; Receptors, Purinergic P1; Tritium | 2000 |
Affinity NMR: decoding DNA binding.
Topics: Adenine; Adenosine; DNA; Ligands; Magnetic Resonance Spectroscopy; Oligonucleotides; Spectrum Analysis; Thiamine | 1999 |
Adenosine-mediated killing of cultured epithelial cancer cells.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Apoptosis; Breast Neoplasms; Carcinoma, Squamous Cell; Cell Division; Cell Survival; Coformycin; Deoxyadenosines; Dipyridamole; Enzyme Inhibitors; Female; Humans; Kinetics; Ovarian Neoplasms; Pentostatin; Tumor Cells, Cultured | 2000 |
Synthesis of S-adenosyl-L-homocysteine hydrolase inhibitors and their biological activities.
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Antimalarials; Antiviral Agents; Enzyme Inhibitors; Humans; Hydrolases | 1999 |
Adenosine and its receptor agonists regulate nitric oxide production and RAW 264.7 macrophages via both receptor binding and its downstream metabolites-inosine.
Topics: Adenine; Adenosine; Bacterial Toxins; Cell Line; Dose-Response Relationship, Drug; Dyneins; Enterotoxins; Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Humans; Hypoxanthine; Inosine; Lipopolysaccharides; Macrophages; Nitric Oxide; Nitric Oxide Synthase; Purinergic P1 Receptor Agonists | 2000 |
Evidence for increased dorsal hippocampal adenosine release and metabolism during pharmacologically induced seizures in rats.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Bicuculline; Convulsants; Disease Models, Animal; Electroencephalography; Enzyme Inhibitors; Excitatory Amino Acid Agonists; GABA Antagonists; Guanosine; Hippocampus; Hypoxanthine; Inosine; Kainic Acid; Male; Microdialysis; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures; Xanthine | 2000 |
Structural factors that determine the ability of adenosine and related compounds to activate the cardiac ryanodine receptor.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Binding, Competitive; Guanosine Triphosphate; Heart; In Vitro Techniques; Ion Channel Gating; Models, Molecular; Myocardium; Ryanodine Receptor Calcium Release Channel; Sheep; Vasodilator Agents | 2000 |
Purine-induced alterations of dopamine metabolism in rat pheochromocytoma PC12 cells.
Topics: Adenine; Adenosine; Animals; Disease Models, Animal; Dopamine; Guanine; Guanosine; Hypoxanthine; Neostriatum; Neural Pathways; Neurons; Parkinson Disease; PC12 Cells; Purines; Rats; Substantia Nigra; Uric Acid; Xanthine | 2000 |
Purine uptake and release in rat C6 glioma cells: nucleoside transport and purine metabolism under ATP-depleting conditions.
Topics: Adenine; Adenosine; Adenosine Triphosphate; AMP Deaminase; Animals; Carrier Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Equilibrative Nucleoside Transport Proteins; Equilibrative-Nucleoside Transporter 2; Formycins; Glioma; Hypoxanthine; Inosine; Iodoacetates; Nucleosides; Phosphodiesterase Inhibitors; Purines; Rats; Reverse Transcriptase Polymerase Chain Reaction; Sodium; Sodium Cyanide; Thioinosine; Tumor Cells, Cultured | 2000 |
Selective transport of adenosine into porcine coronary smooth muscle.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Animals; Biological Transport; Carrier Proteins; Coronary Vessels; Dinoprost; Dipyridamole; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Female; In Vitro Techniques; Muscle, Smooth, Vascular; Purinergic P1 Receptor Agonists; Substrate Specificity; Swine; Thioinosine; Vasoconstriction; Vasodilation; Vasodilator Agents | 2000 |
Substrate binding in vitro and kinetics of RsrI [N6-adenine] DNA methyltransferase.
Topics: Adenine; Adenosine; Binding Sites; Buffers; Carbon Radioisotopes; Catalysis; Chromatography, High Pressure Liquid; Coenzymes; DNA; DNA Methylation; DNA-Binding Proteins; Fluorescence; Kinetics; Nucleic Acid Conformation; Protein Binding; Rhodobacter sphaeroides; S-Adenosylhomocysteine; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific); Substrate Specificity; Thermodynamics | 2000 |
DNA binding properties in vivo and target recognition domain sequence alignment analyses of wild-type and mutant RsrI [N6-adenine] DNA methyltransferases.
Topics: Adenine; Adenosine; Amino Acid Sequence; Amino Acid Substitution; Bacteriophages; Binding Sites; Catalysis; DNA; DNA Methylation; DNA-Binding Proteins; Escherichia coli; Gene Expression Regulation, Bacterial; Isopropyl Thiogalactoside; Lysogeny; Molecular Sequence Data; Mutation; Phylogeny; Plasmids; Protein Binding; Protein Structure, Tertiary; Sequence Alignment; Site-Specific DNA-Methyltransferase (Adenine-Specific); Substrate Specificity; Thermodynamics | 2000 |
Nucleoside binding site of herpes simplex type 1 thymidine kinase analyzed by X-ray crystallography.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Amino Acid Substitution; Antiviral Agents; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Enzyme Inhibitors; Herpesvirus 1, Human; Mutation; Nucleosides; Organophosphonates; Prodrugs; Protein Structure, Tertiary; Stereoisomerism; Substrate Specificity; Thymidine; Thymidine Kinase; Viral Proteins; Water | 2000 |
Contribution of the adenine base to the activity of adenophostin A investigated using a base replacement strategy.
Topics: Adenine; Adenosine; Animals; Calcium; Calcium Channel Agonists; Calcium Channels; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Liver; Magnetic Resonance Spectroscopy; Membranes; Radioligand Assay; Rats; Receptors, Cytoplasmic and Nuclear; Spectrometry, Mass, Fast Atom Bombardment; Structure-Activity Relationship | 2000 |
Ischemic-like condition releases norepinephrine and purines from different sources in superfused rat spleen strips.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Hypoxanthine; Inosine; Ischemia; Male; Norepinephrine; Rats; Rats, Wistar; Spleen; Sympathectomy; Sympathetic Nervous System; Sympathomimetics; Tetrodotoxin; Tritium; Vasodilator Agents; Xanthine | 2000 |
Biomesogenic matrix systems.
Topics: Adenine; Adenosine; Calorimetry, Differential Scanning; Macromolecular Substances; Magnetic Resonance Spectroscopy; Microscopy, Polarization; Models, Molecular; Nucleic Acid Conformation; Poly U; Polyribonucleotides; Thermodynamics | 2000 |
Extracellular ATP formation on vascular endothelial cells is mediated by ecto-nucleotide kinase activities via phosphotransfer reactions.
Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenylate Kinase; Apyrase; Cells, Cultured; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Kinetics; Luminescent Measurements; Membrane Proteins; Nucleoside-Diphosphate Kinase; Phosphates; Phosphorylation; Phosphotransferases (Phosphate Group Acceptor); Substrate Specificity | 2001 |
Adenosine signaling in outer medullary descending vasa recta.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Angiotensin II; Animals; Calcimycin; Calcium; Colforsin; Cyclic AMP; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Female; Ionophores; Kidney Medulla; Kinetics; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Signal Transduction; Thromboxane A2; Vasodilation | 2001 |
Renal interstitial adenosine metabolism during ischemia in dogs.
Topics: Adenine; Adenosine; Animals; Antibiotics, Antineoplastic; Dogs; Extracellular Space; Hypoxanthine; Inosine; Ischemia; Kidney; Tubercidin | 2001 |
Regulation of protoporphyrin IX biosynthesis by intraplastidic compartmentalization and adenosine triphosphate.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Aminolevulinic Acid; Chemical Fractionation; Chloroplasts; Cucumis sativus; Dithiothreitol; Hydroxamic Acids; Hydroxymethylbilane Synthase; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Plastids; Porphobilinogen Synthase; Protoporphyrinogen Oxidase; Protoporphyrins; Thylakoids | 2000 |
A(1) or A(3) adenosine receptors induce late preconditioning against infarction in conscious rabbits by different mechanisms.
Topics: Adenine; Adenosine; Animals; Binding, Competitive; Cell Line; Consciousness; Decanoic Acids; Humans; Hydroxy Acids; Iodine Radioisotopes; Ischemic Preconditioning, Myocardial; Membranes; Myocardial Infarction; Nitroarginine; Norbornanes; Phenethylamines; Rabbits; Radioligand Assay; Receptor, Adenosine A3; Receptors, Purinergic P1 | 2001 |
Tryptophan environment in adenosine deaminase. I. Enzyme modification with N-bromosuccinimide in the presence of adenosine and EHNA analogues.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Binding Sites; Brain; Bromosuccinimide; Cattle; Enzyme Inhibitors; Kinetics; Protein Conformation; Spleen; Tryptophan | 2001 |
Ascorbic acid changes the pattern of purine metabolism during germination of white spruce somatic embryos.
Topics: Adenine; Adenosine; Ascorbic Acid; Germination; Inosine; Picea; Purines; Trees | 2001 |
Ring-Constrained (N)-methanocarba nucleosides as adenosine receptor agonists: independent 5'-uronamide and 2'-deoxy modifications.
Topics: Adenine; Adenosine; Animals; Binding, Competitive; Brain; Cell Line; Cell Membrane; CHO Cells; Cricetinae; Cyclopentanes; Humans; Nucleosides; Protein Binding; Purinergic P1 Receptor Agonists; Rats; Receptors, Purinergic P1; Structure-Activity Relationship; Transfection | 2001 |
Cytokinin production by plant growth promoting rhizobacteria and selected mutants.
Topics: Adenine; Adenosine; Burkholderia; Cytokinins; Gibberellins; Indoleacetic Acids; Isopentenyladenosine; Lactuca; Plant Roots; Pseudomonas | 2001 |
Activation of presynaptic A1-receptors by endogenous adenosine inhibits acetylcholine release in the guinea-pig ileum.
Topics: Acetylcholine; Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Cholinergic Fibers; Dipyridamole; Dose-Response Relationship, Drug; Electrophysiology; Enzyme Inhibitors; Female; Guinea Pigs; Ileum; Isotope Labeling; Male; Models, Biological; Muscle Contraction; Muscle, Smooth; Receptors, Purinergic P1; Vasodilator Agents; Xanthines | 2001 |
Identification of two distinct vasodilator pathways activated by ATP in the mesenteric bed of the rat.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Arachidonic Acids; Capsaicin; Dose-Response Relationship, Drug; Endocannabinoids; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Histamine; In Vitro Techniques; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Piperidines; Polyunsaturated Alkamides; Potassium Chloride; Pyrazoles; Pyrilamine; Quinoxalines; Rats; Rats, Wistar; Rimonabant; Signal Transduction; Stereoisomerism; Theophylline; Vasodilation | 2001 |
Role of cyclic nucleotides in vasodilations of the rat thoracic aorta induced by adenosine analogues.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Acetylcholine; Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Male; Nitroprusside; Nucleotides, Cyclic; Oxadiazoles; Purinones; Quinazolines; Quinoxalines; Rats; Rats, Wistar; Vasodilation; Vasodilator Agents | 2001 |
Some aspects of the role of vitamin B12 in nucleic acid synthesis in a neoplastic C3H mouse cell strain. I. Growth studies.
Topics: Adenine; Adenosine; Animals; Cell Division; Cytidine; Deoxyadenosines; Deoxycytidine; Deoxyuridine; DNA, Neoplasm; Folic Acid; Guanine; Mice; Nucleic Acid Precursors; Nucleosides; Pyrimidines; Thymidine; Tumor Cells, Cultured; Uridine; Vitamin B 12 | 1970 |
Inhibition of adenosine deaminase attenuates endotoxin-induced release of cytokines in vivo in rats.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Blood Pressure; Caffeine; Catecholamines; Cytokines; Endotoxemia; Endotoxins; Enzyme Inhibitors; Heart; Heart Rate; Male; Propranolol; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Renin; Xanthines | 2001 |
Binding of adenine and adenine-related compounds to the clay montmorillonite and the mineral hydroxylapatite.
Topics: Adenine; Adenosine; Aminoimidazole Carboxamide; Bentonite; Binding Sites; Durapatite; Evolution, Chemical; Evolution, Molecular; Hydrogen-Ion Concentration; Hypoxanthine; Nucleosides; Nucleotides; Origin of Life; Purines; Pyrimidines; RNA | 1995 |
Nonenzymatic template-directed synthesis on hairpin oligonucleotides. 3. Incorporation of adenosine and uridine residues.
Topics: Adenine; Adenosine; Base Composition; Base Sequence; Cytidine Monophosphate; Cytosine; Guanine; Guanosine Monophosphate; Molecular Sequence Data; Oligonucleotides; Polymers; Templates, Genetic; Thymidine; Thymine; Uridine | 1992 |
Nonenzymatic oligomerization reactions on templates containing inosinic acid or diaminopurine nucleotide residues.
Topics: 2-Aminopurine; Adenine; Adenosine; Adenosine Monophosphate; Base Pairing; Cytidine Monophosphate; Cytosine; DNA Primers; Evolution, Chemical; Evolution, Molecular; Exobiology; Guanine; Inosine Monophosphate; RNA; Templates, Genetic; Uracil; Uridine Monophosphate | 1999 |
Adenine derivatives as phosphate-activating groups for the regioselective formation of 3',5'-linked oligoadenylates on montmorillonite: possible phosphate-activating groups for the prebiotic synthesis of RNA.
Topics: 4-Aminopyridine; Adenine; Adenosine; Adenosine Monophosphate; Bentonite; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Evolution, Molecular; Magnetic Resonance Spectroscopy; Oligonucleotides; Origin of Life; RNA; Uridine Monophosphate | 1997 |
Cardioprotection with adenosine metabolism inhibitors in ischemic-reperfused mouse heart.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Enzyme Inhibitors; Female; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Perfusion; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Tubercidin | 2001 |
Protection from reperfusion injury after cardiac transplantation by inhibition of adenosine metabolism and nucleotide precursor supply.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Cardioplegic Solutions; Creatinine; Deoxyadenosines; Enzyme Inhibitors; Heart Transplantation; In Vitro Techniques; Inflammation; Male; Myocardial Reperfusion Injury; Myocardium; Neutrophil Infiltration; Perfusion; Rats; Rats, Sprague-Dawley; Ribose; Treatment Outcome | 2001 |
Kinetic analysis of the action of P-site analogs.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Binding Sites; Cyclic AMP; Dialysis; Diphosphates; Enzyme Inhibitors; In Vitro Techniques; Kinetics; Ligands; Models, Biological | 2002 |
Guanine nucleosides and Jurkat cell death: roles of ATP depletion and accumulation of deoxyribonucleotides.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Apoptosis; Cell Nucleus; Cell Separation; Deoxyadenosines; Deoxyguanosine; Deoxyribonucleotides; Flow Cytometry; Guanine; Guanosine; Guanosine Triphosphate; Humans; Jurkat Cells; K562 Cells; Leukocytes; Time Factors | 2001 |
Evidence for the presence of A(1) adenosine receptors in the aorta of spontaneously hypertensive rats.
Topics: Adenine; Adenosine; Animals; Aorta; Culture Techniques; Dose-Response Relationship, Drug; Endothelium, Vascular; Free Radical Scavengers; Hypertension; Indomethacin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norbornanes; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Theobromine; Vasodilation | 2001 |
Inhibition of S-adenosylhomocysteine hydrolase by acyclic sugar adenosine analogue D-eritadenine. Crystal structure of S-adenosylhomocysteine hydrolase complexed with D-eritadenine.
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Animals; Anticholesteremic Agents; Binding Sites; Crystallography, X-Ray; Escherichia coli; Hydrolases; Models, Chemical; Models, Molecular; Plasmids; Protein Binding; Rats; Ultraviolet Rays | 2002 |
Changes in properties of adenosine transporters in Trypanosoma evansi and modes of selection of resistance to the melaminophenyl arsenical drug, Mel Cy.
Topics: Adenine; Adenosine; Animals; Arsenicals; Biological Transport; Biomarkers; Carrier Proteins; Diminazene; Dose-Response Relationship, Drug; Drug Resistance; Inosine; Membrane Transport Proteins; Nucleoside Transport Proteins; Parasitic Sensitivity Tests; Trypanocidal Agents; Trypanosoma | 2001 |
The role of 5'-deoxy-5'-methyl thioadenosine phosphorylase in cardiac adenosine breakdown and adenine production.
Topics: Adenine; Adenosine; Animals; Myocardium; Purine-Nucleoside Phosphorylase; Rats; Rats, Wistar | 2000 |
The effect of adenosine metabolism inhibition and nucleotide precursor supply on adenosine production in human heart endothelial cells.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Adenosine Triphosphate; Cells, Cultured; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; Humans; Nucleotides; Pentostatin; Phosphates; Ribose; Tubercidin | 2000 |
Enhanced endogenous adenosine production and protection of the heart after transplantation.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Adenosine Triphosphate; Animals; Guanosine Triphosphate; Heart; Heart Transplantation; Myocardium; Rats; Ribose | 2000 |
Charcoal affects early development and hormonal concentrations of somatic embryos of hybrid larch.
Topics: Abscisic Acid; Adenine; Adenosine; Charcoal; Indoleacetic Acids; Isopentenyladenosine; Larix; Plant Growth Regulators; Seeds; Trees; Zeatin | 2002 |
Mechanisms of apoptosis induced by purine nucleosides in astrocytes.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Apoptosis; Astrocytes; Carrier Proteins; Cells, Cultured; Central Nervous System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Guanine; Guanosine; Hypoxanthine; Inosine; Male; Purine Nucleosides; Purinergic P1 Receptor Antagonists; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A3; Receptors, Purinergic P1; RNA, Messenger | 2002 |
Does endogenous or exogenous adenosine facilitate the functional recovery of the cochlea after ischemia?
Topics: Action Potentials; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Cochlea; Enzyme Inhibitors; Guinea Pigs; Ischemia; Recovery of Function; Reperfusion Injury; Time Factors; Vasodilator Agents | 2002 |
Cassette mutagenesis and photoaffinity labeling of adenine binding domain of ADP regulatory site within human glutamate dehydrogenase.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Amino Acid Sequence; Animals; Azides; Binding Sites; Glutamate Dehydrogenase; Humans; Mammals; Molecular Sequence Data; Mutagenesis, Insertional; Mutagenesis, Site-Directed; Peptides; Photoaffinity Labels; Protein Structure, Tertiary; Tyrosine | 2002 |
Hydrolysis of N-methyl-D-aspartate receptor-stimulated cAMP and cGMP by PDE4 and PDE2 phosphodiesterases in primary neuronal cultures of rat cerebral cortex and hippocampus.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Adenosine; Animals; Cells, Cultured; Cerebral Cortex; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 2; Cyclic Nucleotide Phosphodiesterases, Type 4; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Guanylate Cyclase; Hippocampus; N-Methylaspartate; Neurons; Nitric Oxide Donors; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Rolipram | 2002 |
The purine nucleoside phosphorylase from Trichomonas vaginalis is a homologue of the bacterial enzyme.
Topics: Adenine; Adenosine; Amino Acid Sequence; Animals; Bacterial Proteins; Binding, Competitive; Catalysis; DNA, Complementary; Enzyme Inhibitors; Escherichia coli; Formycins; Kinetics; Molecular Sequence Data; Protozoan Proteins; Purine-Nucleoside Phosphorylase; Recombinant Proteins; Sequence Alignment; Sequence Analysis, Protein; Sequence Homology, Amino Acid; Substrate Specificity; Trichomonas vaginalis | 2002 |
Purine metabolism and release during cardioprotection with hyperkalemia and hypothermia.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Animals; Guinea Pigs; Heart; Hyperkalemia; Hypothermia; Hypoxanthine; Inosine; L-Lactate Dehydrogenase; Lactates; Myocardium; Purines; Reperfusion Injury; Temperature; Time Factors; Xanthine | 2002 |
Broad spectrum anticonvulsant activity of BW534U87: possible role of an adenosine-dependent mechanism.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Amygdala; Animals; Anticonvulsants; Convulsants; Dose-Response Relationship, Drug; Electroshock; Enzyme Inhibitors; Female; Kindling, Neurologic; Male; Mice; Pentylenetetrazole; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Seizures; Triazoles; Xanthines | 2002 |
Adenosine A(2a) receptor-mediated inhibition of rod opsin mRNA expression in tiger salamander.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenylyl Cyclases; Ambystoma; Animals; Cells, Cultured; Colforsin; Darkness; Enzyme Inhibitors; Gene Expression Regulation; Purinergic P1 Receptor Agonists; Receptor, Adenosine A2A; Receptors, Purinergic P1; Retina; Retinal Rod Photoreceptor Cells; RNA, Messenger; Rod Opsins | 2002 |
Effects of an adenosine kinase inhibitor and an adenosine deaminase inhibitor on accumulation of extracellular adenosine by equine articular chondrocytes.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Cartilage, Articular; Chondrocytes; Enzyme Inhibitors; Horses; Lipopolysaccharides; Nitric Oxide; Nitrites; Tubercidin | 2002 |
Amyloplast formation in cultured tobacco BY-2 cells requires a high cytokinin content.
Topics: 2,4-Dichlorophenoxyacetic Acid; Adenine; Adenosine; Benzyl Compounds; Cells, Cultured; Cytokinins; Gene Expression Regulation; Glucose-1-Phosphate Adenylyltransferase; Hemiterpenes; Isopentenyladenosine; Kinetin; Lovastatin; Mass Spectrometry; Mevalonic Acid; Nicotiana; Nucleotidyltransferases; Organophosphorus Compounds; Plant Growth Regulators; Plastids; Purines; RNA, Messenger; Starch; Zeatin | 2002 |
Medicinal chemistry and pharmacology of A2B adenosine receptors.
Topics: Adenine; Adenosine; Animals; Drug Design; Humans; Molecular Sequence Data; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A2B; Receptors, Purinergic P1; Sequence Homology; Structure-Activity Relationship; Xanthines | 2003 |
Tracer adenosine: a novel myocardial flow marker.
Topics: Adenine; Adenosine; Alprostadil; Animals; Carbon Radioisotopes; Coronary Circulation; Dogs; Isotope Labeling; Microspheres; Myocardial Ischemia; Myocardium; Sensitivity and Specificity; Statistics as Topic; Ventricular Dysfunction, Left | 2003 |
Extracellular purines from cells of seminiferous tubules.
Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Animals; Cells, Cultured; Dipyridamole; Enzyme Inhibitors; Extracellular Space; Germ Cells; Kinetics; Male; Paracrine Communication; Phosphodiesterase Inhibitors; Purines; Rats; Rats, Wistar; Receptors, Purinergic; Seminiferous Tubules; Sertoli Cells; Thioinosine | 2003 |
[Studies on chemical constituents from the water-soluble part of root of Angelica dahurica].
Topics: Adenine; Adenosine; Angelica; Plant Roots; Plants, Medicinal; Solubility; Water | 2002 |
The human D2 dopamine receptor synergizes with the A2A adenosine receptor to stimulate adenylyl cyclase in PC12 cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenine; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenylyl Cyclases; Animals; Benzamides; Binding, Competitive; Cell Cycle; Cell Membrane; Cofilin 1; Colforsin; Cyclic AMP; Cytoskeletal Proteins; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Enzyme Activation; Gene Expression; Glutamic Acid; Humans; Membrane Potentials; Patch-Clamp Techniques; PC12 Cells; Pertussis Toxin; Phenethylamines; Phosphodiesterase Inhibitors; Phosphoproteins; Propionates; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrrolidines; Quinpirole; Radioligand Assay; Rats; Receptors, Dopamine D2; Receptors, Purinergic P1; Thionucleotides; Transfection; Triazines; Triazoles; Xenopus Proteins | 2003 |
Activation of A(3) receptors by endogenous adenosine inhibits synaptic transmission during hypoxia in rat cortical neurons.
Topics: Adenine; Adenosine; Animals; Cell Hypoxia; Cerebral Cortex; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Guanosine; Guanosine Diphosphate; In Vitro Techniques; Male; Neurotransmitter Uptake Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyramidal Cells; Rats; Rats, Wistar; Receptor, Adenosine A3; Receptors, Purinergic P1; Synaptic Transmission; Thionucleosides; Thionucleotides; Time Factors | 2003 |
An angiogenic switch in macrophages involving synergy between Toll-like receptors 2, 4, 7, and 9 and adenosine A(2A) receptors.
Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Angiogenesis Inhibitors; Animals; Cells, Cultured; DNA-Binding Proteins; Endothelial Growth Factors; Enzyme Inhibitors; Humans; Intercellular Signaling Peptides and Proteins; Lipopolysaccharides; Lipoproteins; Lymphokines; Macrophages, Peritoneal; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Physiologic; NF-kappa B; Paclitaxel; Purinergic P1 Receptor Agonists; Receptor, Adenosine A2A; Receptors, Cell Surface; Receptors, Purinergic P1; Toll-Like Receptor 2; Toll-Like Receptor 3; Toll-Like Receptor 4; Toll-Like Receptor 5; Toll-Like Receptor 7; Toll-Like Receptor 9; Toll-Like Receptors; Tumor Necrosis Factor-alpha; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Vasodilator Agents | 2003 |
Adenine, an inhibitor of platelet aggregation, from the leaves of Cassia alata.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Cassia; Collagen; Humans; In Vitro Techniques; Light; Plant Leaves; Platelet Aggregation; Platelet Aggregation Inhibitors; Scattering, Radiation; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet | 2003 |
The mechanism of adenine thiomethylriboside formation.
Topics: Adenine; Adenosine; Yeasts | 1953 |
Formation of adenosine by cell-free extracts of Escherichia coli.
Topics: Adenine; Adenosine; Biochemical Phenomena; Escherichia coli; Inosine | 1954 |
[The role of adenine (vitamin B4) in the metabolism of organic compounds and its repercussions on acid-base equilibrium].
Topics: Acid-Base Equilibrium; Adenine; Adenosine; Blood; Nucleotides; Organic Chemicals; Vitamins | 1954 |
Cytological studies on the antimetabolite action of 2, 6-diaminopurine in Vicia faba roots.
Topics: 2-Aminopurine; Adenine; Adenosine; Antimetabolites; Cell Division; Deoxyadenosines; DNA; Growth; Guanine; Hypoxanthine; Purines; Vicia faba | 1955 |
[Substances derived from Crataegus. VIII. Adenosine, adenine, guanine, uric acid].
Topics: Adenine; Adenosine; Crataegus; Guanine; Plant Extracts; Plants; Uric Acid | 1955 |
Enzymic transfer of the ribosyl group from inosine to adenine.
Topics: Adenine; Adenosine; Humans; Inosine; Xanthines | 1957 |
Metabolism of 2,6-diaminopurine: S-adenosylmethionine as methyl donor for 2-methylamino-6-aminopurine synthesis.
Topics: 2-Aminopurine; Adenine; Adenosine; Metabolic Networks and Pathways; Methionine; Purines; S-Adenosylmethionine | 1959 |
Inhibition of aminonucleoside nephrosis in rats. I. The effect of adenine, adenosine and adenosine triphosphate.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Animals; Nephrosis; Nucleosides; Nucleotides; Puromycin Aminonucleoside; Rats | 1961 |
Separation of adenine, hypoxanthine, and the 5'-(mono-,di-,and tri-)-phosphates of adenosine and inosine by one-dimensional paper chromatography.
Topics: Adenine; Adenine Nucleotides; Adenosine; Chromatography; Chromatography, Paper; Hypoxanthine; Inosine; Nucleosides; Nucleotides; Phosphates; Retinal Degeneration; Retinal Detachment | 1962 |
[Study of the action of adenine, adenosine and adenosine-5-monophosphoric acid on experimental porphyria in the white rat and on the in vitro biosynthesis of porphyrins].
Topics: Adenine; Adenosine; Animals; In Vitro Techniques; Nucleosides; Nucleotides; Porifera; Porphyrias; Porphyrins; Rats | 1962 |
Phosphorylated carbohydrate intermediates of the human erythrocyte during storage in acid citrate dextrose. III. Effect of incubation at 37 degrees C. with inosine, inosine plus adenine, and adenosine after storage for 6, 10, 14 and 18 weeks.
Topics: Adenine; Adenosine; Blood Preservation; Carbohydrates; Citrates; Citric Acid; Cold Temperature; Erythrocytes; Glucose; Humans; Inosine; Nucleosides; Nucleotides | 1962 |
Formation of adenosine by ultra-violet irradiation of a solution of adenine and ribose.
Topics: Adenine; Adenosine; Nucleosides; Ribose; Solutions; Ultraviolet Rays; Viola | 1963 |
Effect of magnesium and calcium ions on the fluorescence of the protonated ring of adenine, adenosine, adenosine 5'-phosphate, adenosine diphosphate, and adenosine triphosphate.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Calcium; Fluorescence; Ions; Magnesium; Nucleosides | 1963 |
Biosynthesis of S-adenosylmethionine by Saccharomyces cerevisiae. I. Adenine and methionine requirments.
Topics: Adenine; Adenosine; Guanine; Methionine; Naphthalenes; S-Adenosylmethionine; Saccharomyces cerevisiae; Sulfonamides; Yeasts | 1962 |
OCCURRENCE OF NUCLEOTIDES IN CULTURE FLUIDS OF MICROORGANISMS. V. EXCRETION OF ADENOSINE CYCLIC 3',5'-PHOSPHATE BY BREVIBACTERIUM LIQUEFACIENS SP. N.
Topics: Adenine; Adenosine; Amino Acids; Arthrobacter; Brevibacterium; Japan; Metabolism; Nucleotides; Phosphates; Research | 1963 |
INSTABILITY OF THE TERMINAL ADENOSINE OF SOLUBLE RIBONUCLEIC ACID OF ESCHERICHIA COLI IN VIVO.
Topics: Adenine; Adenosine; Carbon Isotopes; Chromatography; Escherichia coli; Metabolism; Mutation; Nucleosides; Research; RNA; RNA, Bacterial | 1964 |
THE INFLUENCE OF ADENOSINE, INOSINE AND ADENINE ON THE ELECTROPHORETIC PATTERNS OF RED CELL HEMOLYSATES OF STORED BLOOD.
Topics: Adenine; Adenosine; Blood Preservation; Electrophoresis; Erythrocytes; Humans; Inosine; Nucleosides; Protein Hydrolysates; Research | 1964 |
ANTIMICROBIAL ACTIVITY OF 2-FLUOROADENOSINE AND 2-FLUOROADENINE.
Topics: Adenine; Adenosine; Anti-Infective Agents; Bacteria; Nucleosides; Pharmacology; Research | 1964 |
STUDIES ON DONOR-ACCEPTOR COMPLEXES RELATING TO THE INTRAMOLECULAR ASSOCIATION OF THE RIBOFLAVIN AND ADENOSINE MOIETIES OF FLAVIN- ADENINE DINUCLEOTIDE.
Topics: Adenine; Adenosine; Chemical Phenomena; Chemistry; Flavin-Adenine Dinucleotide; Flavins; Fluorescence; Hydrogen-Ion Concentration; Nucleosides; Research; Riboflavin | 1965 |
THE SYNTHESIS OF ADENOSINE-5'-PHOSPHATE SIMULATED BY THYROID HORMONES.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Aspartic Acid; Chromatography; Fumarates; Guanine Nucleotides; Metabolism; Nucleotides; Pharmacology; Phosphates; Research; Spectrophotometry; Tetrazolium Salts; Thymus Gland; Thyroid Hormones; Thyroxine; Triiodothyronine | 1965 |
METHODS FOR AUTOMATIC NUCLEOTIDE-SEQUENCE ANALYSIS. MULTICOMPONENT SPECTROPHOTOMETRIC ANALYSIS OF MIXTURES OF NUCLEIC ACID COMPONENTS BY A LEAST-SQUARES PROCEDURE.
Topics: Adenine; Adenosine; Biochemical Phenomena; Biochemistry; Computers; Electronic Data Processing; Guanosine; Least-Squares Analysis; Nucleosides; Nucleotides; Oligonucleotides; Research; RNA; Sequence Analysis; Spectrophotometry; Ultraviolet Rays | 1965 |
REGULATION OF XANTHINE DEHYDROGENASE IN CHICK LIVER. EFFECT OF STARVATION AND OF ADMINISTRATION OF PURINES AND PURINE NUCLEOSIDES.
Topics: Adenine; Adenosine; Animals; Chickens; Cortisone; Guanine; Guanosine; Hypoxanthines; Inosine; Liver; Nucleosides; Pharmacology; Poultry; Purine Nucleosides; Purines; Puromycin; Research; Ribonucleosides; Spectrophotometry; Starvation; Xanthine Dehydrogenase; Xanthine Oxidase; Xanthines | 1965 |
Biosynthesis of nucleic acid purines. I. Formation of guanine from adenine compounds in bone marrow extracts.
Topics: Adenine; Adenosine; Biochemical Phenomena; Bone Marrow; Guanine; Nucleic Acids; Purines; Tissue Extracts | 1955 |
[Cardiovascular effects of adenylic acid derivaties; adenine, inosine, adenosine, A5MP and of a related compound, cytidine].
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Cardiovascular System; Cytidine; Inosine; Nucleosides; Nucleotides | 1961 |
Extracellular ATP and adenosine induce cell apoptosis of human hepatoma Li-7A cells via the A3 adenosine receptor.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Apoptosis; Biological Transport; Carcinoma, Hepatocellular; Caspase 3; Caspases; Cell Division; Cell Line; Cell Line, Tumor; Coformycin; Dipyridamole; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Humans; In Situ Nick-End Labeling; Nucleosides; Oligonucleotide Array Sequence Analysis; Receptor, Adenosine A3; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Uridine Triphosphate | 2003 |
Mechanisms of arsenical and diamidine uptake and resistance in Trypanosoma brucei.
Topics: Adenine; Adenosine; Animals; Arsenicals; Benzamidines; Cell Death; Cell Division; Diminazene; Drug Resistance; Female; Gene Silencing; Hypoxanthine; Inhibitory Concentration 50; Inosine; Melarsoprol; Mice; Mutation; Nucleoside Transport Proteins; Pentamidine; Stilbamidines; Trypanosoma brucei brucei | 2003 |
Endogenous adenosine modulation of 22Na uptake by rat brain synaptosomes.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Brain; In Vitro Techniques; Rats; Rats, Wistar; Sodium; Sodium Radioisotopes; Synaptosomes; Thioinosine | 2003 |
Nucleobase adenine as a trophic factor acting on Purkinje cells.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Astrocytes; Cell Count; Cells, Cultured; Coculture Techniques; Enzyme Inhibitors; Fetus; Immunohistochemistry; Nerve Growth Factors; Purkinje Cells; Rats; Rats, Wistar | 2003 |
"Acceptor-donor-acceptor" motifs recognize the Watson-Crick, Hoogsteen and Sugar "donor-acceptor-donor" edges of adenine and adenosine-containing ligands.
Topics: Adenine; Adenosine; Amino Acid Motifs; Amino Acyl-tRNA Synthetases; Animals; Humans; Protein Binding; Protein Conformation | 2003 |
Simultaneous separation and determination of active components in Cordyceps sinensis and Cordyceps militarris by LC/ESI-MS.
Topics: Adenine; Adenosine; Cordyceps; Deoxyadenosines; Drugs, Chinese Herbal; Gas Chromatography-Mass Spectrometry; Hypoxanthine; Nucleosides; Principal Component Analysis; Spectrometry, Mass, Electrospray Ionization | 2003 |
Synthesis and biological evaluation of disubstituted N6-cyclopentyladenine analogues: the search for a neutral antagonist with high affinity for the adenosine A1 receptor.
Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Animals; Cell Line; CHO Cells; Cricetinae; Drug Evaluation, Preclinical; Humans; Receptor, Adenosine A1 | 2004 |
Changes in adenosine transport associated with melaminophenyl arsenical (Mel CY) resistance in Trypanosoma evansi: down-regulation and affinity changes of the P2 transporter.
Topics: Adenine; Adenosine; Animals; Arsenicals; Diminazene; Down-Regulation; Drug Resistance; Inosine; Kinetics; Nucleoside Transport Proteins; Trypanocidal Agents; Trypanosoma | 2003 |
Regulation of adenosine receptor subtypes during cultivation of human monocytes: role of receptors in preventing lipopolysaccharide-triggered respiratory burst.
Topics: Adenine; Adenosine; Adenosine Deaminase; Base Sequence; Calcium Signaling; Cells, Cultured; Dipyridamole; DNA, Complementary; Humans; In Vitro Techniques; Lipopolysaccharides; Monocytes; Purinergic P1 Receptor Antagonists; Reactive Oxygen Species; Receptors, Purinergic P1; Respiratory Burst; RNA, Messenger | 2004 |
Stimulus- and cell-type-specific release of purines in cultured rat forebrain astrocytes and neurons.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Astrocytes; Cell Hypoxia; Cells, Cultured; Deoxyglucose; Glucose; Inosine; Iodoacetic Acid; Neurons; Oligomycins; Prosencephalon; Purines; Rats; Stimulation, Chemical | 2004 |
Conformational and inframolecular studies of the protonation of adenophostin analogues lacking the adenine moiety.
Topics: Adenine; Adenosine; Bacterial Proteins; Calcium Channel Agonists; Inositol 1,4,5-Trisphosphate; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Phosphorus; Phosphorylation; Protein Conformation; Protons | 2004 |
Efficient synthesis of an adenosine A2a agonist: glycosylation of 2-haloadenines and an N2-alkyl-6-chloroguanine.
Topics: Adenine; Adenosine; Adenosine A2 Receptor Agonists; Alkylation; Anti-Inflammatory Agents; Glycosylation; Guanine; Hydrocarbons, Halogenated; Maleates; Molecular Structure; Purines; Ribose | 2004 |
Positive inotropic effect of the inhibition of cyclic GMP-stimulated 3',5'-cyclic nucleotide phosphodiesterase (PDE2) on guinea pig left atria in eu- and hyperthyroidism.
Topics: Adenine; Adenosine; Animals; Cardiotonic Agents; Culture Techniques; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 2; Guinea Pigs; Heart Atria; Hyperthyroidism; Male; Myocardial Contraction; Phosphoric Diester Hydrolases; Thioinosine | 2003 |
NMR regulatory analysis: determination and characterization of S-adenosyl-L-methionine in dietary supplements.
Topics: Adenine; Adenosine; Deuterium Oxide; Dietary Supplements; Magnetic Resonance Spectroscopy; Methionine; Reference Standards; S-Adenosylmethionine; Stereoisomerism; United States | 2004 |
Adenosine induces apoptosis in the human gastric cancer cells via an intrinsic pathway relevant to activation of AMP-activated protein kinase.
Topics: Adenine; Adenosine; Adenylate Kinase; Aminoimidazole Carboxamide; Apoptosis; Caspase Inhibitors; Dipyridamole; Drug Interactions; Enzyme Activation; Humans; Membrane Potentials; Mitochondria; Receptors, Purinergic P1; Ribonucleotides; Signal Transduction; Stomach Neoplasms; Tumor Cells, Cultured | 2004 |
Nucleotide release provides a mechanism for airway surface liquid homeostasis.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Cell Line; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Firefly Luciferin; Humans; Hydrolysis; Luciferases; Microscopy, Confocal; Mucous Membrane; Nucleotides; Protein Kinase C; Purines; Receptor, Adenosine A2B; Respiratory Mucosa; Respiratory System; Time Factors; Trachea | 2004 |
Development and validation of a high-performance liquid chromatography assay and a capillary electrophoresis assay for the analysis of adenosine and the degradation product adenine in infusions.
Topics: Adenine; Adenosine; Chromatography, High Pressure Liquid; Electrophoresis, Capillary | 2004 |
Protective effect of adenosine and purine nucleos(t)ides against the death by hydrogen peroxide and glucose deprivation in rat primary astrocytes.
Topics: Adenine; Adenosine; Analysis of Variance; Animals; Animals, Newborn; Astrocytes; Benzimidazoles; Carbocyanines; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Glucose; Hydrogen Peroxide; In Vitro Techniques; L-Lactate Dehydrogenase; Membrane Potentials; Mitochondria; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Rats; Rats, Sprague-Dawley; Theobromine; Thioinosine; Time Factors; Xanthines | 2005 |
Adenophostin A and analogues modified at the adenine moiety: synthesis, conformational analysis and biological activity.
Topics: Adenine; Adenosine; Animals; Binding Sites; Calcium; Calcium Channels; Cell Line; Chickens; Hydrogen Bonding; Inositol 1,4,5-Trisphosphate Receptors; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Rats; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; Solutions; Structure-Activity Relationship | 2005 |
Chemical engineering of the peptidyl transferase center reveals an important role of the 2'-hydroxyl group of A2451.
Topics: Adenine; Adenosine; Base Sequence; Chemical Engineering; Molecular Sequence Data; Mutation; Nucleosides; Peptidyl Transferases; Ribosomes; RNA, Ribosomal, 23S | 2005 |
The role of extracellular adenosine in regulating mossy fiber synaptic plasticity.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Animals; Animals, Newborn; Bicuculline; Cyclopentanes; Cyclopropanes; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glycine; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Mossy Fibers, Hippocampal; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptor, Adenosine A1; Synapses; Synaptic Transmission; Xanthines | 2005 |
Adenosine-dependent induction of glutathione peroxidase 1 in human primary endothelial cells and protection against oxidative stress.
Topics: Adenine; Adenosine; Apoptosis; Cells, Cultured; Endothelial Cells; Enzyme Induction; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Hydrogen Peroxide; Oxidative Stress; Protein Kinase C; Receptors, Purinergic P1; RNA, Messenger; Signal Transduction | 2005 |
Identification of specific [3H]adenine-binding sites in rat brain membranes.
Topics: Adenine; Adenosine; Animals; Binding Sites; Brain; Cell Membrane; Male; Purines; Rats; Rats, Wistar; Receptors, Purinergic; Structure-Activity Relationship; Tissue Distribution; Tritium | 2005 |
Identification of a subversive substrate of Trichomonas vaginalis purine nucleoside phosphorylase and the crystal structure of the enzyme-substrate complex.
Topics: Adenine; Adenosine; Animals; Binding Sites; Catalysis; Crystallography, X-Ray; Dose-Response Relationship, Drug; Electrons; Formycins; Humans; Hydrolysis; Inhibitory Concentration 50; Inosine; Ligands; Models, Chemical; Models, Molecular; Protein Binding; Protein Conformation; Purine-Nucleoside Phosphorylase; Recombinant Proteins; Substrate Specificity; Threonine; Time Factors; Trichomonas vaginalis; X-Rays | 2005 |
New adenosine A2A receptor antagonists: actions on Parkinson's disease models.
Topics: Adenine; Adenosine; Adenosine A2 Receptor Antagonists; Animals; Antiparkinson Agents; Behavior, Animal; Binding, Competitive; Catalepsy; CHO Cells; Cricetinae; Cricetulus; Disease Models, Animal; Drug Synergism; Levodopa; Male; Molecular Structure; Parkinson Disease; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Tritium | 2005 |
Domain motions and the open-to-closed conformational transition of an enzyme: a normal mode analysis of S-adenosyl-L-homocysteine hydrolase.
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Animals; Binding Sites; Catalysis; Crystallography, X-Ray; Dimerization; Enzyme Inhibitors; Humans; Models, Chemical; Models, Molecular; Protein Conformation; Protein Structure, Tertiary; Rats; Substrate Specificity; Thermodynamics | 2005 |
Transition from nonspecific to specific DNA interactions along the substrate-recognition pathway of dam methyltransferase.
Topics: Adenine; Adenosine; Amino Acid Sequence; Amino Acid Substitution; Bacteriophage T4; Base Sequence; Binding Sites; Catalysis; Catalytic Domain; Crystallography, X-Ray; DNA; Escherichia coli; Escherichia coli Proteins; Kinetics; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Oligonucleotides; Protein Binding; Protein Conformation; S-Adenosylhomocysteine; Sequence Homology, Amino Acid; Site-Specific DNA-Methyltransferase (Adenine-Specific); Substrate Specificity; Viral Proteins | 2005 |
Ischemic preconditioning protects post-ischemic renal function in anesthetized dogs: role of adenosine and adenine nucleotides.
Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Animals; Blood Pressure; Dogs; Ischemic Preconditioning; Kidney; Renal Circulation; Reperfusion Injury; Urine; Xanthines | 2005 |
Lidoflazine combined with nucleotide precursors increases ATP content and adenosine production in cardiomyocytes.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Analysis of Variance; Animals; Lidoflazine; Myocytes, Cardiac; Nucleotides; Rats; Ribose; Time Factors; Vasodilator Agents | 2005 |
AMPD1 C34T mutation selectively affects AMP-deaminase activity in the human heart.
Topics: Adenine; Adenosine; Adenosine Monophosphate; AMP Deaminase; Biopsy; Chromatography, High Pressure Liquid; Codon, Nonsense; Genotype; Heterozygote; Humans; Mutation; Myocardium; Polymorphism, Restriction Fragment Length; Polymorphism, Single-Stranded Conformational | 2005 |
Adenosine down-regulates giant depolarizing potentials in the developing rat hippocampus by exerting a negative control on glutamatergic inputs.
Topics: Action Potentials; Adenine; Adenosine; Adenosine Triphosphate; Analgesics; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamic Acid; Hippocampus; In Vitro Techniques; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar; Thioinosine; Xanthines | 2005 |
Apoptosis induced by N6-substituted derivatives of adenosine is related to intracellular accumulation of corresponding mononucleotides in HL-60 cells.
Topics: Adenine; Adenine Nucleotides; Adenine Phosphoribosyltransferase; Adenosine; Adenosine Kinase; Adenosine Monophosphate; Amino Acid Chloromethyl Ketones; Apoptosis; Caspase 3; Caspase Inhibitors; Caspases; Enzyme Inhibitors; HL-60 Cells; Humans; Phosphorylation | 2005 |
Adenosine and deoxyadenosine induces apoptosis in oestrogen receptor-positive and -negative human breast cancer cells via the intrinsic pathway.
Topics: Adenine; Adenosine; Apoptosis; Breast Neoplasms; Caspase 3; Caspase 9; Caspases; Cell Line, Tumor; Cell Proliferation; Deoxyadenosines; Dose-Response Relationship, Drug; Humans; Receptors, Estrogen; Thioinosine; Time Factors | 2005 |
Adenine and adenosine salvage pathways in erythrocytes and the role of S-adenosylhomocysteine hydrolase. A theoretical study using elementary flux modes.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Kinase; Adenosine Triphosphate; Adenosylhomocysteinase; ADP Ribose Transferases; Erythrocytes; Humans; Metabolic Diseases; Models, Biological; Purine-Nucleoside Phosphorylase | 2005 |
Adenosine A1 receptors mediate inhibition of cAMP formation in vitro in the pontine, REM sleep induction zone.
Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Adenylyl Cyclase Inhibitors; Animals; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Microinjections; Phenethylamines; Pons; Rats; Rats, Long-Evans; Receptor, Adenosine A1; Sleep, REM | 2005 |
Ring-expanded analogues of natural oxetanocin: (+) and (-) hydroxymethyl isodideoxyadenosine.
Topics: Adenine; Adenosine; Adenosine Deaminase; Anti-HIV Agents; Antiviral Agents; Glucosamine; Glucose; Magnetic Resonance Spectroscopy; Models, Chemical; Purine Nucleosides; Purine-Nucleoside Phosphorylase; Stereoisomerism; Ultraviolet Rays; X-Rays | 2005 |
Condensation of nucleobases at mercury/aqueous solution interface--a structural perspective using hydrogen bonding considerations.
Topics: Adenine; Adenosine; Adsorption; Cytosine; Electrodes; Electrolytes; Guanine; Hydrogen Bonding; Mercury; Potassium; Purines; Pyrimidines; Sodium; Solutions; Thermodynamics; Thiouracil; Thymine; Uracil; Water | 2002 |
Signaling pathways for modulation of mouse sperm motility by adenosine and catecholamine agonists.
Topics: Adenine; Adenosine; Adenylyl Cyclases; Animals; Calcium; Catecholamines; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Catalytic Subunits; Dideoxyadenosine; Enzyme Inhibitors; Imines; Isoquinolines; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Protein Kinase Inhibitors; Signal Transduction; Sperm Motility; Sperm Tail; Sulfonamides | 2006 |
Assay of adenosine deaminase isoforms by HPLC.
Topics: Adenine; Adenosine; Adenosine Deaminase; Benzyl Compounds; Chromatography, High Pressure Liquid; Hypoxanthine; Inosine; Isoenzymes | 2006 |
Conformational transitions in RNA single uridine and adenosine bulge structures: a molecular dynamics free energy simulation study.
Topics: Adenine; Adenosine; Base Composition; Biophysics; Computer Simulation; Ligands; Models, Chemical; Models, Molecular; Molecular Conformation; Nucleic Acid Conformation; Nucleic Acids; Nucleotides; Protein Binding; RNA; Stereoisomerism; Thermodynamics; Uridine; Water | 2006 |
Role of the second transmembrane domain of rat adenosine A1 receptor in ligand-receptor interaction.
Topics: Adenine; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Amino Acid Sequence; Animals; Cell Line; Cell Membrane; Humans; Hydrophobic and Hydrophilic Interactions; Ligands; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Structure, Tertiary; Rats; Receptor, Adenosine A1; Xanthines | 2006 |
The role of adenosine in chondrocyte death in murine osteoarthritis and in a murine chondrocyte cell line.
Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Apoptosis; Cartilage, Articular; Cell Death; Cell Line; Chondrocytes; DNA Fragmentation; Enzyme Inhibitors; Homocysteine; Male; Mice; Mice, Inbred Strains; Osteoarthritis; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; Tubercidin | 2006 |
Adenosine2A receptor vasodilation of rat preglomerular microvessels is mediated by EETs that activate the cAMP/PKA pathway.
Topics: 8,11,14-Eicosatrienoic Acid; Adenine; Adenosine; Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Antihypertensive Agents; Arachidonic Acids; Benzamides; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, Gs; Kidney Glomerulus; Male; Peptides; Phenethylamines; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, Adenosine A2; Renal Artery; Signal Transduction; Vasodilation; Vasodilator Agents | 2006 |
Cloning and characterization of a second form of the rice adenine phosphoribosyl transferase gene (OsAPT2) and its association with TGMS.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Adenosine Monophosphate; Alleles; Amino Acid Sequence; Blotting, Northern; Cloning, Molecular; Computational Biology; DNA Primers; DNA, Complementary; Down-Regulation; Exons; Gene Expression Regulation, Plant; Genes, Plant; Genetic Vectors; Homozygote; Hot Temperature; Introns; Light; Models, Genetic; Molecular Sequence Data; Nucleotides; Oligonucleotides, Antisense; Oryza; Phenotype; Plant Leaves; Plant Physiological Phenomena; Pollen; Polymerase Chain Reaction; Protein Structure, Secondary; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Amino Acid; Temperature; Transgenes | 2006 |
Moderate hypoxia induces xanthine oxidoreductase activity in arterial endothelial cells.
Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta; Cattle; Endothelium, Vascular; Enzyme Induction; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Oxygen; Purinergic P1 Receptor Antagonists; Reactive Oxygen Species; Xanthine Oxidase | 2006 |
Fine-tuning modulation of myenteric motoneurons by endogenous adenosine: on the role of secreted adenosine deaminase.
Topics: Acetylcholine; Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase; Analysis of Variance; Animals; Calcium; Cholinergic Antagonists; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Female; In Vitro Techniques; Male; Motor Neurons; Myenteric Plexus; Neural Inhibition; Purinergic Antagonists; Purines; Rats; Rats, Wistar; Tritium | 2006 |
Effects of adenosine on myocardial glucose and palmitate metabolism after transient ischemia: role of 5'-AMP-activated protein kinase.
Topics: Acetyl-CoA Carboxylase; Adenine; Adenosine; Adenosine Triphosphate; Adrenergic alpha-Antagonists; AMP-Activated Protein Kinases; Animals; Energy Metabolism; Enzyme Activation; Glucose; Glycogen; Glycolysis; Heart; Ischemic Attack, Transient; Male; Multienzyme Complexes; Myocardium; Palmitates; Phentolamine; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Ventricular Function, Left | 2006 |
Adenosine A2A receptor modulation of juvenile female rat skeletal muscle microvessel permeability.
Topics: Adenine; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Aging; Animals; Arterioles; Cell Membrane Permeability; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Gene Expression Regulation; Muscle, Skeletal; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A2B; RNA, Messenger; Serum Albumin; Triazines; Triazoles; Vasodilator Agents; Venules | 2006 |
Fluorescent N2,N3-epsilon-adenine nucleoside and nucleotide probes: synthesis, spectroscopic properties, and biochemical evaluation.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Calcium; Cell Line; Cyclization; Enzyme Inhibitors; Fluorescent Dyes; Humans; Molecular Structure; Purinergic P2 Receptor Agonists; Rats; Receptors, Purinergic P2Y1; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 2006 |
Femtosecond time- and wavelength-resolved fluorescence and absorption spectroscopic study of the excited states of adenosine and an adenine oligomer.
Topics: Adenine; Adenosine; Oligonucleotides; Poly A; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 2006 |
Modulation of ischaemic contracture in mouse hearts: a 'supraphysiological' response to adenosine.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Animals; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Contraction; Myocardial Reperfusion Injury; Receptor, Adenosine A1; Theophylline; Time Factors; Ventricular Function, Left; Ventricular Pressure; Xanthines | 2007 |
Anandamide inhibits endothelin-1 production by human cultured endothelial cells: a new vascular action of this endocannabinoid.
Topics: Adenine; Adenosine; Arachidonic Acids; Cannabinoid Receptor Modulators; Cells, Cultured; Dose-Response Relationship, Drug; Endocannabinoids; Endothelial Cells; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Humans; Nitric Oxide; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Xanthines | 2007 |
A new functional, chemical proteomics technology to identify purine nucleotide binding sites in complex proteomes.
Topics: Adenine; Adenosine; Binding Sites; Cell Extracts; Chromatography, Liquid; Humans; Jurkat Cells; Models, Molecular; Proteins; Proteome; Proteomics; Tandem Mass Spectrometry | 2006 |
Mechanism of 3-deazaguanine transport in the rat heart.
Topics: Adenine; Adenosine; Animals; Dinitrophenols; Female; Guanine; In Vitro Techniques; Male; Myocardium; Nucleoside Transport Proteins; Radioisotope Dilution Technique; Rats; Sodium; Thymidine; Thymine; Tritium | 2006 |
The novel adenosine A2a antagonist ST1535 potentiates the effects of a threshold dose of l-dopa in unilaterally 6-OHDA-lesioned rats.
Topics: Adenine; Adenosine; Adenosine A2 Receptor Antagonists; Animals; Brain; Disease Models, Animal; Dopamine Agents; Dose-Response Relationship, Drug; Drug Synergism; Exploratory Behavior; Levodopa; Male; Movement; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar; Receptor, Adenosine A2A; Sympatholytics; Triazoles | 2007 |
Inhibition and structure of Trichomonas vaginalis purine nucleoside phosphorylase with picomolar transition state analogues.
Topics: Adenine; Adenosine; Animals; Catalytic Domain; Crystallization; Crystallography, X-Ray; Models, Molecular; Purine-Nucleoside Phosphorylase; Pyrrolidines; Substrate Specificity; Trichomonas vaginalis | 2007 |
A fundamental regulatory role of formate on thuringiensin production by resting cell of Bacillus thuringiensis YBT-032.
Topics: Adenine; Adenosine; Bacillus thuringiensis; Cell Line; Dose-Response Relationship, Drug; Formates; Gene Expression Regulation, Bacterial; Glycolysis; Pentose Phosphate Pathway; Signal Transduction; Sugar Acids | 2007 |
Methotrexate and erythro-9-(2-hydroxynon-3-yl) adenine therapy for rat adjuvant arthritis and the effect of methotrexate on in vivo purine metabolism.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Aminoimidazole Carboxamide; Animals; Antirheumatic Agents; Arthritis, Experimental; Biomarkers; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Inhibitors; Methotrexate; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Purines; Rats; Ribonucleosides | 2007 |
[Study on HPEC fingerprint of cultured Cordyceps militaris].
Topics: Adenine; Adenosine; Chromatography, High Pressure Liquid; Cordyceps; Culture Techniques; Deoxyadenosines; Electrophoresis, Capillary; Plant Extracts; Quality Control; Uridine | 2007 |
Adenosine deaminase inhibition enhances the inotropic response mediated by A1 adenosine receptor in hyperthyroid guinea pig atrium.
Topics: Adenine; Adenosine; Adenosine A1 Receptor Agonists; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Benzyl Compounds; Cyclic Nucleotide Phosphodiesterases, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Heart Atria; Hyperthyroidism; Inosine; Male; Myocardial Contraction; Pentostatin; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Receptor, Adenosine A1; Signal Transduction; Thyroxine | 2007 |
Determination of the impurity profile of adenosine by means of ion-pair reversed-phase chromatography.
Topics: Adenine; Adenosine; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Drug Contamination; Europe; Guanosine; Inosine; Pharmaceutical Preparations; Pharmacopoeias as Topic; Quality Control; Quaternary Ammonium Compounds; Reproducibility of Results; Technology, Pharmaceutical; Temperature; Uridine | 2006 |
Facile synthesis of 1',2'-cis-beta-pyranosyladenine nucleosides.
Topics: Acetates; Adenine; Adenosine; Camphor; Carbohydrates; Cesium; Chemistry; Galactosides; Glucosides; Models, Chemical; Nucleosides; Purines; Pyrans; Quaternary Ammonium Compounds; Sulfonic Acids | 2007 |
Interaction of A2A adenosine and D2 dopamine receptors modulates corticostriatal glutamatergic transmission.
Topics: Adenine; Adenosine; Animals; Cerebral Cortex; Corpus Striatum; Dopamine Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Male; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Phenethylamines; Quinpirole; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Dopamine D2; Synaptic Transmission; Triazines; Triazoles | 2007 |
Rofecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor increases pentylenetetrazol seizure threshold in mice: possible involvement of adenosinergic mechanism.
Topics: Adenine; Adenosine; Analysis of Variance; Animals; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Lactones; Male; Mice; Pentylenetetrazole; Seizures; Sulfones | 2008 |
Enhancement of glutathione production by altering adenosine metabolism of Escherichia coli in a coupled ATP regeneration system with Saccharomyces cerevisiae.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Bioreactors; Escherichia coli; Glucose; Glutathione; Glycolysis; Hypoxanthine; Industrial Microbiology; Saccharomyces cerevisiae | 2008 |
A Phytochemically characterized extract of Cordyceps militaris and cordycepin protect hippocampal neurons from ischemic injury in gerbils.
Topics: Adenine; Adenosine; Aldehydes; Animals; Antifungal Agents; Biological Products; Brain Injuries; Cordyceps; Deoxyadenosines; Gerbillinae; Hippocampus; Lipid Peroxidation; Male; Neurons | 2008 |
Kinetic characterization of adenosine deaminase activity in zebrafish (Danio rerio) brain.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Brain; Cattle; Deamination; Hydrogen-Ion Concentration; Kinetics; Membranes; Metals; Solubility; Substrate Specificity; Temperature; Time Factors; Zebrafish | 2008 |
Inhibition of erythroblast growth and fetal hemoglobin production by ribofuranose-substituted adenosine derivatives.
Topics: Adenine; Adenosine; Adult; Cell Cycle; Cell Differentiation; Cell Proliferation; Colforsin; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; Erythroblasts; Erythropoietin; Fetal Hemoglobin; Gene Expression Regulation; Gene Silencing; Globins; Humans; Kinetics; RNA, Messenger; Signal Transduction; Stem Cell Factor; Transforming Growth Factor beta | 2008 |
Gas-phase protonation thermochemistry of adenosine.
Topics: Adenine; Adenosine; Algorithms; Gases; Hydrogen Bonding; Kinetics; Molecular Structure; Protons; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Thermodynamics | 2008 |
A cell wall-bound adenosine nucleosidase is involved in the salvage of extracellular ATP in Solanum tuberosum.
Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Triphosphate; Apyrase; Cell Wall; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; N-Glycosyl Hydrolases; Plant Tubers; Plants, Genetically Modified; Solanum tuberosum | 2008 |
Adenosine as an endogenous regulating factor of hippocampal sharp waves.
Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Animals; Dizocilpine Maleate; Electric Stimulation; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Membrane Potentials; Mice; Mice, Inbred C57BL; Microelectrodes; Nucleoside Transport Proteins; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Receptor, Adenosine A1; Receptors, N-Methyl-D-Aspartate; Theophylline; Xanthines | 2009 |
The combination of adenine, adenosine, and adenylic acid with serum albumin.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Albumins; Humans; Serum Albumin | 1948 |
[Study on HPLC fingerprint characteristic analysis of Cordyceps sinensis and its similar products].
Topics: Adenine; Adenosine; Chromatography, High Pressure Liquid; Cordyceps; Deoxyadenosines; Drugs, Chinese Herbal; Powders; Quality Control; Solvents; Uracil; Uridine | 2008 |
Structure and dynamics of the ApA, ApC, CpA, and CpC RNA dinucleoside monophosphates resolved with NMR scalar spin-spin couplings.
Topics: Adenine; Adenosine; Cytosine; Dinucleoside Phosphates; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; RNA; Stress, Mechanical | 2009 |
Third-generation immucillins: syntheses and bioactivities of acyclic immucillin inhibitors of human purine nucleoside phosphorylase.
Topics: Adenine; Adenosine; Catalytic Domain; Drug Design; Humans; Molecular Conformation; Pliability; Protein Binding; Purine-Nucleoside Phosphorylase; Pyrrolidines; Structure-Activity Relationship | 2009 |
Russian isolates of potato spindle tuber viroid.
Topics: Adenine; Adenosine; Base Composition; Base Sequence; Cytosine; Molecular Sequence Data; Plant Diseases; Plant Viruses; RNA, Viral; Russia; Solanum tuberosum; Viroids | 2008 |
Pentamidine movement across the murine blood-brain and blood-cerebrospinal fluid barriers: effect of trypanosome infection, combination therapy, P-glycoprotein, and multidrug resistance-associated protein.
Topics: Adenine; Adenosine; Animals; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Blood-Brain Barrier; Brain; Cerebrospinal Fluid; Disease Models, Animal; Drug Interactions; Eflornithine; Indomethacin; Male; Melarsoprol; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Mice, Knockout; Multidrug Resistance-Associated Proteins; Nifurtimox; Pentamidine; Perfusion; Suramin; Trypanosoma brucei brucei; Trypanosomiasis, African | 2009 |
Photoexcitation of adenine cation radical [A*+] in the near UV-vis region produces sugar radicals in adenosine and in its nucleotides.
Topics: Adenine; Adenosine; Carbohydrates; Cations; Free Radicals; Light; Molecular Structure; Nucleotides; Photochemical Processes | 2008 |
Sequence selective formation of 1,N(6)-ethenoadenine in DNA by furan-conjugated probe.
Topics: Adenine; Adenosine; Base Sequence; DNA; DNA Adducts; DNA Probes; Fluorescent Dyes; Furans; Mutation; Oligodeoxyribonucleotides; Oxidation-Reduction | 2009 |
A novel mouse model for sudden unexpected death in epilepsy (SUDEP): role of impaired adenosine clearance.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Caffeine; Cause of Death; Death, Sudden; Disease Models, Animal; Enzyme Inhibitors; Epilepsy; Kainic Acid; Mice; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Risk Factors; Seizures; Survival Analysis; Tubercidin | 2010 |
Endocannabinoid 1 and 2 (CB(1); CB(2)) receptor agonists affect negatively cow luteal function in vitro.
Topics: Adenine; Adenosine; Animals; Arachidonic Acids; Cattle; Corpus Luteum; Dinoprost; Dinoprostone; Female; In Vitro Techniques; Indoles; Organophosphonates; Piperidines; Pregnancy; Progesterone; Pyrazoles; Pyrrolidines; Random Allocation; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2 | 2009 |
Caspase-4 activation in association with decreased adenosine deaminase activity may be a factor for gastric ulcer.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adult; Aged; Animals; Apoptosis; Caspase 3; Caspases, Initiator; Cell Line, Tumor; Cell Survival; Enzyme Activation; Enzyme Inhibitors; Female; Gastric Mucosa; Humans; Intestinal Mucosa; Male; Middle Aged; Osmolar Concentration; Rats; Stomach; Stomach Ulcer | 2010 |
Heavy involvement of stringent transcription control depending on the adenine or guanine species of the transcription initiation site in glucose and pyruvate metabolism in Bacillus subtilis.
Topics: Adenine; Adenosine; Bacillus subtilis; Bacterial Proteins; Base Sequence; DNA, Bacterial; Gene Expression Regulation, Bacterial; Glucose; Guanine; Operon; Pyruvic Acid; Transcription Initiation Site; Transcription, Genetic | 2010 |
A synchrotron radiation study of the one-dimensional complex of sodium with (1S)-N-carboxylato-1-(9-deazaadenin-9-yl)-1,4-dideoxy-1,4-imino-D-ribitol, a member of the 'immucillin' family.
Topics: Adenine; Adenosine; Crystallography, X-Ray; Hydrogen Bonding; Molecular Conformation; Polymers; Pyrrolidines; Radiation; Ribitol; Sodium; Stereoisomerism; Synchrotrons | 2010 |
Experiments on the synthesis of purine nucleosides; 9-beta-d-mannopyranosidoadenine; a proof of the location of the sugar residue in adenosine.
Topics: Adenine; Adenosine; Nucleosides; Purine Nucleosides; Purines | 1947 |
Rapid determination of adenosine deaminase kinetics using fast-scan cyclic voltammetry.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Caffeine; Cattle; Electric Conductivity; Electrochemistry; Enzyme Assays; Kinetics; Oxidation-Reduction; Pentostatin; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Silver; Time Factors | 2010 |
Ultrafast dynamics of 1-ethynylpyrene-modified RNA: a photophysical probe of intercalation.
Topics: Adenine; Adenosine; Intercalating Agents; Pyrenes; RNA; Spectrometry, Fluorescence; Time Factors | 2010 |
Growth and metastases of human lung cancer are inhibited in mouse xenografts by a transition state analogue of 5'-methylthioadenosine phosphorylase.
Topics: Adenine; Adenosine; Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Deoxyadenosines; Humans; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Purine-Nucleoside Phosphorylase; Pyrrolidines; S-Adenosylmethionine; Thionucleosides; Transplantation, Heterologous; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays | 2011 |
Determination of the nucleosides and nucleobases in Tuber samples by dispersive solid-phase extraction combined with liquid chromatography-mass spectrometry.
Topics: Adenine; Adenosine; Agaricales; Chromatography, High Pressure Liquid; Chromatography, Liquid; Fermentation; Guanine; Guanosine; Hypoxanthine; Inosine; Mass Spectrometry; Nucleosides; Plant Extracts; Plant Tubers; Solid Phase Extraction; Tandem Mass Spectrometry; Uridine | 2011 |
Biochemistry. The two faces of SAM.
Topics: Adenine; Adenosine; Bacterial Proteins; Biocatalysis; Catalytic Domain; Chemical Phenomena; Cysteine; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Proteins; Methylation; Methyltransferases; RNA, Bacterial; RNA, Ribosomal, 23S; S-Adenosylmethionine; Staphylococcus aureus | 2011 |
Adenosine activation of A(2B) receptor(s) is essential for stimulated epithelial ciliary motility and clearance.
Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Bronchi; Cattle; Cilia; Epithelial Cells; Female; In Vitro Techniques; Isoproterenol; Mice; Mice, Knockout; Movement; Procaterol; Protein Isoforms; Purinergic Agents; Receptors, Purinergic P1; Trachea | 2011 |
Effects of A₂A adenosine receptor blockade or stimulation on alcohol intake in alcohol-preferring rats.
Topics: Adenine; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Alcohol Drinking; Animals; Dose-Response Relationship, Drug; Drinking; Drug Delivery Systems; Eating; Ethanol; Male; Motor Activity; Phenethylamines; Rats; Receptor, Adenosine A2A; Self Administration; Thionucleosides | 2012 |
Distinctive immunoregulatory effects of adenosine on T cells of older humans.
Topics: Adenine; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adult; Age Factors; Aged; Aged, 80 and over; Antigens, CD; Apyrase; CD28 Antigens; Cells, Cultured; Chemotaxis; Cytokines; Dose-Response Relationship, Drug; Female; Flow Cytometry; Humans; Male; Middle Aged; Phenethylamines; Pyrimidines; T-Lymphocytes; Triazoles; Young Adult | 2012 |
Discovery of bacterial NAD⁺-dependent DNA ligase inhibitors: improvements in clearance of adenosine series.
Topics: Adenine; Adenosine; Administration, Oral; Animals; Anti-Bacterial Agents; Biological Availability; Chromatography, Liquid; DNA Ligases; Dogs; Drug Design; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fluorine; Inhibitory Concentration 50; Mass Spectrometry; Models, Chemical; NAD; Rats | 2012 |
Adenosine-mediated cardiovascular toxicity in amitriptyline-poisoned rats.
Topics: Adenine; Adenosine; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Arterial Pressure; Glucose; Heart Rate; Infusions, Intravenous; Long QT Syndrome; Male; Rats; Rats, Wistar; Thioinosine; Time Factors | 2012 |
Contribution of phosphates and adenine to the potency of adenophostins at the IP₃ receptor: synthesis of all possible bisphosphates of adenophostin A.
Topics: Adenine; Adenosine; Animals; Calcium; Cell Line; Chickens; Inositol 1,4,5-Trisphosphate Receptors; Models, Molecular; Organophosphates; Rats; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship | 2012 |
Simultaneous determination of five nucleosides and nucleobases of Rehmannia glutinosa Libosch. by high performance liquid chromatography.
Topics: Adenine; Adenosine; Chromatography, High Pressure Liquid; Guanosine; Hypoxanthine; Nucleosides; Plants, Medicinal; Rehmannia; Uridine | 2011 |
High-resolution structures of complexes of plant S-adenosyl-L-homocysteine hydrolase (Lupinus luteus).
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Crystallography, X-Ray; Deoxyadenosines; Hydrolases; Lupinus; Methylation; Models, Molecular; Molecular Conformation; Protein Binding; S-Adenosylhomocysteine; S-Adenosylmethionine | 2012 |
Reduced adenosine release from the aged mammalian heart.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adrenergic Antagonists; Aging; Animals; Heart; Hydrolases; Male; Myocardial Contraction; Perfusion; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; Sodium Chloride; Tubercidin | 2012 |
The role of autophagy during coxsackievirus infection of neural progenitor and stem cells.
Topics: Adenine; Adenosine; Animals; Autophagy; Cell Differentiation; Coxsackievirus Infections; Enterovirus B, Human; Fibroblast Growth Factors; Green Fluorescent Proteins; HeLa Cells; Humans; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Neural Stem Cells; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Sirolimus; Transduction, Genetic; Viral Load; Viral Proteins; Virus Replication | 2012 |
Development of a selective activity-based probe for adenylating enzymes: profiling MbtA Involved in siderophore biosynthesis from Mycobacterium tuberculosis.
Topics: Adenine; Adenosine; Antitubercular Agents; Ligases; Microbial Sensitivity Tests; Models, Molecular; Mycobacterium tuberculosis; Siderophores; Structure-Activity Relationship | 2012 |
BF066, a novel dual target antiplatelet agent without significant bleeding.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Arterioles; Chlorides; Collagen; Ferric Compounds; Fibrinogen; Hemorrhage; Humans; Immobilized Proteins; Mice; Mice, Inbred C57BL; Oligopeptides; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptor, Adenosine A2A; Thrombin; Thrombosis | 2012 |
C-3 halo and 3-methyl substituted 5'-nor-3-deazaaristeromycins: synthesis and antiviral properties.
Topics: Adenine; Adenosine; Antiviral Agents; Crystallography, X-Ray; Humans; Models, Molecular; Virus Diseases; Viruses | 2013 |
High-intensity swimming exercise reduces neuropathic pain in an animal model of complex regional pain syndrome type I: evidence for a role of the adenosinergic system.
Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine Deaminase Inhibitors; Animals; Caffeine; Exercise Therapy; Hyperalgesia; Male; Mice; Naloxone; Narcotic Antagonists; Neuralgia; Neurons; Reflex Sympathetic Dystrophy; Swimming; Triazines; Triazoles; Xanthines | 2013 |
A self-assembled luminescent host that selectively senses ATP in water.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Guanosine Triphosphate; Heterocyclic Compounds; Kinetics; Luminescence; Macrocyclic Compounds; Molecular Structure; Nucleotides; Organometallic Compounds; Rhenium; Ruthenium; Water | 2013 |
Time-resolved photoelectron spectroscopy of adenine and adenosine in aqueous solution.
Topics: Adenine; Adenosine; Molecular Structure; Photoelectron Spectroscopy; Solutions; Time Factors; Water | 2013 |
Adenine and adenosine salvage in Leishmania donovani.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Aminohydrolases; Gene Deletion; Leishmania donovani; Metabolic Networks and Pathways | 2013 |
Conformational freedom in tight binding enzymatic transition-state analogues.
Topics: Adenine; Adenosine; Bacteria; Bacterial Proteins; Binding Sites; Catalytic Domain; Escherichia coli; Escherichia coli Proteins; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Molecular Dynamics Simulation; N-Glycosyl Hydrolases; Protein Binding; Pyrrolidines; Vibrio cholerae | 2013 |
Identification and analysis of the constituents in an aqueous extract of Tricholoma matsutake by HPLC coupled with diode array detection/electrospray ionization mass spectrometry.
Topics: Adenine; Adenosine; Chromatography, High Pressure Liquid; Cytidine; Deoxyadenosines; Guanosine; Inosine; Phenylalanine; Riboflavin; Spectrometry, Mass, Electrospray Ionization; Thionucleosides; Tricholoma; Tryptophan; Tyrosine; Uridine; Water | 2013 |
Discovery of a cAMP deaminase that quenches cyclic AMP-dependent regulation.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Adenylyl Cyclases; Amino Acid Sequence; Bacterial Proteins; Cyclic AMP; Cyclic AMP Receptor Protein; Cyclic IMP; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Kinetics; Leptospira interrogans; Molecular Sequence Data; Nucleotide Deaminases; Recombinant Proteins; Substrate Specificity; Transcription, Genetic | 2013 |
Potent inhibition of the C-P lyase nucleosidase PhnI by Immucillin-A triphosphate.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Catalysis; Escherichia coli; Escherichia coli Proteins; Lyases; Magnesium; Models, Chemical; Organophosphonates; Pentosephosphates; Polyphosphates; Pyrrolidines | 2013 |
Bioactive metabolites isolated from Penicillium sp. YY-20, the endophytic fungus from Ginkgo biloba.
Topics: Adenine; Adenosine; Antioxidants; Biological Products; Biphenyl Compounds; Brassica; Deoxyadenosines; Deoxyuridine; Ginkgo biloba; Growth Substances; Molecular Structure; Penicillium; Picrates; Plant Roots; Raphanus | 2014 |
Exploration of novel predictive markers in rat plasma of the early stages of chronic renal failure.
Topics: Adenine; Adenosine; Animals; Biomarkers; Chromatography, Liquid; Cresols; Early Diagnosis; Glycocholic Acid; Indican; Kidney Failure, Chronic; Lysophospholipids; Male; Metabolomics; Multivariate Analysis; Rats; Rats, Sprague-Dawley; Sulfuric Acid Esters; Tandem Mass Spectrometry | 2014 |
Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430.
Topics: Adenine; Adenosine; Administration, Oral; Animals; Antiviral Agents; Disease Models, Animal; DNA-Directed RNA Polymerases; Ebolavirus; Filoviridae; Filoviridae Infections; Hemorrhagic Fever, Ebola; Humans; Injections, Intramuscular; Macaca fascicularis; Marburg Virus Disease; Marburgvirus; Purine Nucleosides; Pyrrolidines; RNA; Time Factors | 2014 |
The influence of four different anticoagulants on dynamic light scattering of platelets.
Topics: Adenine; Adenosine; Anticoagulants; Blood Platelets; Cell Size; Chelating Agents; Citrates; Dipyridamole; Edetic Acid; Glucose; Humans; Light; Phosphates; Platelet-Rich Plasma; Scattering, Radiation; Theophylline | 2014 |
Small molecule, big advance against Marburg virus.
Topics: Adenine; Adenosine; Animals; Antiviral Agents; Bunyaviridae; Disease Models, Animal; Filoviridae; Guinea Pigs; Humans; Macaca fascicularis; Marburg Virus Disease; Marburgvirus; Mice; Purine Nucleosides; Pyrrolidines | 2014 |
IL-6, A1 and A2aR: a crosstalk that modulates BDNF and induces neuroprotection.
Topics: Adenine; Adenosine; Animals; Axotomy; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Interleukin-6; Neuroprotective Agents; Phenethylamines; Rats; Receptor, Adenosine A1; Receptor, Adenosine A2A; Retinal Ganglion Cells | 2014 |
Structural probing of off-target G protein-coupled receptor activities within a series of adenosine/adenine congeners.
Topics: Adenine; Adenosine; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Humans; Molecular Docking Simulation; Protein Binding; Protein Conformation; Receptors, G-Protein-Coupled; Structure-Activity Relationship | 2014 |
BCX4430, a novel nucleoside analog, effectively treats yellow fever in a Hamster model.
Topics: Adenine; Adenosine; Alanine Transaminase; Animals; Antibodies, Neutralizing; Antibodies, Viral; Antiviral Agents; Cells, Cultured; Cricetinae; Disease Models, Animal; Female; Mesocricetus; Purine Nucleosides; Pyrrolidines; Treatment Outcome; Viral Plaque Assay; Viremia; Yellow Fever; Yellow fever virus | 2014 |
Scientific validation of the Chinese caterpillar medicinal mushroom, Ophiocordyceps sinensis (Ascomycetes) from India: immunomodulatory and antioxidant activity.
Topics: Adenine; Adenosine; Animals; Antioxidants; Ascomycota; Cell Line; Cell Survival; Flavonoids; Immunologic Factors; India; Interleukin-1beta; Macrophages, Peritoneal; Nitric Oxide; Phenols; Tumor Necrosis Factor-alpha; Uracil | 2014 |
Modulation of adenosine signaling prevents scopolamine-induced cognitive impairment in zebrafish.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Avoidance Learning; Cognition Disorders; Dipyridamole; Disease Models, Animal; Motor Activity; Muscarinic Antagonists; Nucleoside Transport Proteins; Purinergic P1 Receptor Antagonists; Scopolamine; Signal Transduction; Social Behavior; Zebrafish | 2015 |
Adenosine deaminase inhibitor EHNA exhibits a potent anticancer effect against malignant pleural mesothelioma.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Humans; Mesothelioma; Mice; Mice, Nude; Morpholines; Pleural Neoplasms; Pyrimidines; RNA Interference; RNA, Small Interfering; Transplantation, Heterologous | 2015 |
Role of adenosine signaling on pentylenetetrazole-induced seizures in zebrafish.
Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine Diphosphate; Animals; Benzyl Compounds; Convulsants; Dipyridamole; Gene Expression Regulation; Genes, fos; Pentylenetetrazole; Phenethylamines; Phosphodiesterase Inhibitors; Seizures; Signal Transduction; Thioinosine; Xanthines; Zebrafish | 2015 |
Structure and thermodynamics of N6-methyladenosine in RNA: a spring-loaded base modification.
Topics: Adenine; Adenosine; Base Pairing; Cell Line; Humans; Methylation; Models, Molecular; Ribonucleases; RNA; RNA Stability; Thermodynamics | 2015 |
The pivotal role of the mitochondrial amidoxime reducing component 2 in protecting human cells against apoptotic effects of the base analog N6-hydroxylaminopurine.
Topics: Adenine; Adenosine; Apoptosis; Cytochrome-B(5) Reductase; Cytochromes b5; Gene Expression; HEK293 Cells; HeLa Cells; Humans; Membrane Proteins; Metabolic Detoxication, Phase I; Mitochondria; Mitochondrial Proteins; Oxidoreductases; Poly(ADP-ribose) Polymerases; Proteolysis; RNA, Small Interfering | 2015 |
Infectious disease. Combating emerging viral threats.
Topics: Adenine; Adenosine; Antiviral Agents; Benzamides; Chloroquine; Communicable Diseases, Emerging; Cyclosporins; Cytosine; Dengue; Drug Approval; Drug Design; Erlotinib Hydrochloride; Hemorrhagic Fever, Ebola; Humans; Imatinib Mesylate; Indoles; Organophosphonates; Piperazines; Purine Nucleosides; Pyrimidines; Pyrroles; Pyrrolidines; Quinazolines; Sunitinib; Viruses | 2015 |
Immucillins Impair Leishmania (L.) infantum chagasi and Leishmania (L.) amazonensis Multiplication In Vitro.
Topics: Adenine; Adenosine; Animals; Antiprotozoal Agents; Cell Proliferation; Enzyme Inhibitors; Female; Humans; In Vitro Techniques; Kinetics; Leishmania infantum; Leishmania mexicana; Leishmaniasis, Cutaneous; Leishmaniasis, Visceral; Mice; Mice, Inbred BALB C; Microscopy, Electron, Transmission; N-Glycosyl Hydrolases; Purine Nucleosides; Pyrimidinones; Pyrroles; Pyrrolidines | 2015 |
Structure-Activity Relationships of Neplanocin A Analogues as S-Adenosylhomocysteine Hydrolase Inhibitors and Their Antiviral and Antitumor Activities.
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Animals; Antineoplastic Agents; Antiviral Agents; Cell Line, Tumor; Chlorocebus aethiops; Enzyme Inhibitors; Humans; Molecular Docking Simulation; Neoplasms; Structure-Activity Relationship; Vero Cells; Virus Diseases; Viruses | 2015 |
An adenosine kinase inhibitor, ABT-702, inhibits spinal nociceptive transmission by adenosine release via equilibrative nucleoside transporters in rat.
Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine Deaminase; Adenosine Kinase; Analgesics; Animals; Animals, Newborn; Enzyme Inhibitors; Membrane Potentials; Morpholines; Motor Neurons; Neural Pathways; Nociceptive Pain; Pyrimidines; Reflex; Spinal Cord; Tissue Culture Techniques; Xanthines | 2015 |
Damage/Danger Associated Molecular Patterns (DAMPs) Modulate Chlamydia pecorum and C. trachomatis Serovar E Inclusion Development In Vitro.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Adenosine; Adenosine Triphosphate; Apyrase; Benzyl Compounds; Chlamydia; Chlamydia trachomatis; Cyclic AMP; HeLa Cells; Host-Pathogen Interactions; Humans | 2015 |
Mechanism of Adefovir, Tenofovir and Entecavir Resistance: Molecular Modeling Studies of How A Novel Anti-HBV Agent (FMCA) Can Overcome the Drug Resistance.
Topics: Adenine; Adenosine; Amino Acid Sequence; Antiviral Agents; Binding Sites; Catalytic Domain; Databases, Protein; Drug Resistance, Viral; Gene Products, pol; Guanine; Hepatitis B; Hepatitis B virus; HIV Reverse Transcriptase; Humans; Hydrogen Bonding; Molecular Dynamics Simulation; Molecular Sequence Data; Mutation; Organophosphonates; Sequence Alignment; Tenofovir | 2015 |
Functional identification of SLC43A3 as an equilibrative nucleobase transporter involved in purine salvage in mammals.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Amino Acid Transport Systems; Animals; Biological Transport; Dogs; Equilibrative Nucleoside Transporter 1; HEK293 Cells; HeLa Cells; Hepatocytes; Humans; Hypoxanthine; Liver; Lung; Madin Darby Canine Kidney Cells; Mice; Protein Isoforms; Purines; RNA, Small Interfering; Thymidine; Uridine | 2015 |
Inhibition of adenosine metabolism induces changes in post-ictal depression, respiration, and mortality in genetically epilepsy prone rats.
Topics: Adenine; Adenosine; Animals; Blood Gas Analysis; Brugada Syndrome; Disease Models, Animal; Enzyme Inhibitors; Epilepsy; Female; Genetic Predisposition to Disease; Incidence; Male; Oxygen; Rats; Respiration; Respiration Disorders; Seizures; Sex Characteristics; Tubercidin | 2016 |
Immucillins ImmA and ImmH Are Effective and Non-toxic in the Treatment of Experimental Visceral Leishmaniasis.
Topics: Adenine; Adenosine; Animals; Antibodies, Protozoan; Antiprotozoal Agents; Blood Chemical Analysis; Disease Models, Animal; Drug-Related Side Effects and Adverse Reactions; Female; Gene Expression; Immunophenotyping; Interferon-gamma; Interleukin-10; Leishmania; Leishmaniasis, Visceral; Leukocytes, Mononuclear; Mesocricetus; Mice, Inbred BALB C; Parasite Load; Purine Nucleosides; Pyrimidinones; Pyrrolidines; Spleen; T-Lymphocyte Subsets; Treatment Outcome; Tumor Necrosis Factor-alpha | 2015 |
Enantiomeric 3-deaza-1',6'-isoneplanocin and its 3-bromo analogue: Synthesis by the Ullmann reaction and their antiviral properties.
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Antiviral Agents; Cytomegalovirus; Ebolavirus; Humans; Morbillivirus; Norovirus; Nucleosides; Stereoisomerism | 2016 |
Herbal Lead as Ideal Bioactive Compounds Against Probable Drug Targets of Ebola Virus in Comparison with Known Chemical Analogue: A Computational Drug Discovery Perspective.
Topics: Adenine; Adenosine; Antiviral Agents; Drug Discovery; Ebolavirus; Humans; Molecular Docking Simulation; Purine Nucleosides; Pyrrolidines; Transcription Factors; Viral Matrix Proteins; Viral Proteins; Viral Regulatory and Accessory Proteins | 2017 |
[Determination of Nucleosides and Nucleobases in Natural, Cultured and Tissue Culture Anoectochilus roxburghii Using LC-MS].
Topics: Adenine; Adenosine; Chromatography, Liquid; Drugs, Chinese Herbal; Guanosine; Hypoxanthine; Mass Spectrometry; Nucleosides; Nucleotides; Orchidaceae; Uracil; Uridine | 2015 |
Reactivity of nitrogen atoms in adenine and (Ade)2Cu complexes towards ribose and 2-furanmethanol: Formation of adenosine and kinetin.
Topics: Adenine; Adenosine; Kinetin; Maillard Reaction; Nitrogen; Ribose; Tandem Mass Spectrometry | 2017 |
Simultaneous separation of polar and non-polar mixtures by capillary HPLC based on an ostadecylsilane and taurine derivatized silica continuously packed column.
Topics: Adenine; Adenosine; Biogenic Amines; Chromatography, Liquid; Cytidine; Cytosine; Hydrocarbons; Hydrophobic and Hydrophilic Interactions; Silanes; Silicon Dioxide; Taurine | 2016 |
Efficacy of the broad-spectrum antiviral compound BCX4430 against Zika virus in cell culture and in a mouse model.
Topics: Adenine; Adenosine; Animals; Antiviral Agents; Brain; Cell Line; Disease Models, Animal; Humans; Male; Mice; Purine Nucleosides; Pyrrolidines; RNA, Viral; Testis; Viral Load; Viremia; Virus Replication; Zika Virus; Zika Virus Infection | 2017 |
Evaluation of purine utilization by Lactobacillus gasseri strains with potential to decrease the absorption of food-derived purines in the human intestine.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Diet; Food; Humans; Intestinal Absorption; Lactobacillus gasseri | 2016 |
Targeting ENT1 and adenosine tone for the treatment of Huntington's disease.
Topics: Adenine; Adenosine; Animals; Corpus Striatum; Disease Models, Animal; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; Humans; Huntingtin Protein; Huntington Disease; Indoles; Mice; Mice, Transgenic; Neostriatum; Trinucleotide Repeat Expansion | 2017 |
Butyrate influences intracellular levels of adenine and adenine derivatives in the fungus Penicillium restrictum.
Topics: Adenine; Adenosine; Anti-Infective Agents; Biomass; Butyrates; Chromatography, High Pressure Liquid; Cyclic AMP; Cytoplasm; Hypoxanthine; Microbial Sensitivity Tests; Penicillium; Spores, Fungal; Staphylococcus aureus | 2017 |
Antiviral activity of the adenosine analogue BCX4430 against West Nile virus and tick-borne flaviviruses.
Topics: Adenine; Adenosine; Animals; Antiviral Agents; Cell Line; Cell Survival; Chlorocebus aethiops; Culicidae; Dose-Response Relationship, Drug; Encephalitis Viruses, Tick-Borne; Encephalitis, Tick-Borne; Flavivirus; Purine Nucleosides; Pyrrolidines; Swine; Tick-Borne Diseases; Ticks; Vero Cells; Virus Replication; West Nile virus | 2017 |
New nucleoside hydrolase with transribosylation activity from Agromyces sp. MM-1 and its application for enzymatic synthesis of 2'-O-methylribonucleosides.
Topics: Actinomycetales; Adenine; Adenosine; Biocatalysis; Guanine; Hydrolysis; N-Glycosyl Hydrolases; Uridine | 2018 |
Determination of the Main Nucleosides and Nucleobases in Natural and Cultured Ophiocordyceps xuefengensis.
Topics: Adenine; Adenosine; Animals; Chromatography, High Pressure Liquid; Clerodendrum; Cordyceps; Fruiting Bodies, Fungal; Guanosine; Inosine; Larva; Moths; Nucleosides; Uracil; Uridine | 2017 |
Topics: Adenine; Adenosine; Brazil; Cell Proliferation; Cells, Cultured; Cytokines; Humans; Immunomodulation; Killer Cells, Natural; Leishmania braziliensis; Leishmaniasis, Cutaneous; Leukocytes, Mononuclear; Lymphocyte Activation; Purine-Nucleoside Phosphorylase; Pyrrolidines; Th1 Cells | 2017 |
Salinity Effects on the Adsorption of Nucleic Acid Compounds on Na-Montmorillonite: a Prebiotic Chemistry Experiment.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Adsorption; Bentonite; Origin of Life; Salinity; Sodium | 2018 |
Lactobacillus gasseri PA-3, but not L. gasseri OLL2996, reduces the absorption of purine nucleosides in rats.
Topics: Adenine; Adenosine; Animals; Carbon Radioisotopes; Gastric Absorption; Inosine; Lactobacillus gasseri; Male; Purine Nucleosides; Purines; Rats, Wistar; Species Specificity | 2018 |
Galidesivir limits Rift Valley fever virus infection and disease in Syrian golden hamsters.
Topics: Adenine; Adenosine; Animals; Antiviral Agents; Disease Models, Animal; Injections, Intramuscular; Injections, Intraperitoneal; Liver; Mesocricetus; Purine Nucleosides; Pyrrolidines; Rift Valley Fever; Rift Valley fever virus; Spleen; Survival Analysis; Treatment Outcome | 2018 |
The combination of ribose and adenine promotes adenosine release and attenuates the intensity and frequency of epileptiform activity in hippocampal slices: Evidence for the rapid depletion of cellular ATP during electrographic seizures.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Creatine; Electrophysiological Phenomena; Epilepsy; Extracellular Space; Hippocampus; In Vitro Techniques; Male; Microelectrodes; Rats; Rats, Sprague-Dawley; Ribose; Seizures; Synaptic Transmission | 2018 |
Reduced levels of modified nucleosides in the urine of autistic children. Preliminary studies.
Topics: Adenine; Adenosine; Adolescent; Autistic Disorder; Child; Child, Preschool; Chromatography, Liquid; Female; Guanine; Guanosine; Humans; Male; Mass Spectrometry | 2019 |
An E460D Substitution in the NS5 Protein of Tick-Borne Encephalitis Virus Confers Resistance to the Inhibitor Galidesivir (BCX4430) and Also Attenuates the Virus for Mice.
Topics: Adenine; Adenosine; Alleles; Amino Acid Substitution; Animals; Antiviral Agents; Cell Line; Disease Models, Animal; Drug Resistance, Microbial; Drug Resistance, Viral; Encephalitis Viruses, Tick-Borne; Encephalitis, Tick-Borne; Genotype; Mice; Mutation; Pyrrolidines; Viral Nonstructural Proteins | 2019 |
FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle.
Topics: Adenine; Adenosine; Adenosine Deaminase; Chromatography, Liquid; HEK293 Cells; Hep G2 Cells; Humans; Intracellular Signaling Peptides and Proteins; Mass Spectrometry; Multifunctional Enzymes; Phosphorylation; Proteins; Purine Nucleotides; Purines | 2020 |
Adenosine-producing regulatory B cells in head and neck cancer.
Topics: Adenine; Adenosine; Agammaglobulinaemia Tyrosine Kinase; Animals; Apoptosis; B-Lymphocytes, Regulatory; Case-Control Studies; Cell Proliferation; Head and Neck Neoplasms; Humans; Male; Mice; Piperidines; Prognosis; Pyrazoles; Pyrimidines; Squamous Cell Carcinoma of Head and Neck; Tumor Cells, Cultured; Tumor Microenvironment; Xenograft Model Antitumor Assays | 2020 |
Novel Coronavirus Polymerase and Nucleotidyl-Transferase Structures: Potential to Target New Outbreaks.
Topics: Adenine; Adenosine; Amides; Antiviral Agents; Betacoronavirus; Binding Sites; Coronavirus Infections; COVID-19; Humans; Molecular Docking Simulation; Nucleotidyltransferases; Pandemics; Pneumonia, Viral; Protein Structure, Tertiary; Pyrazines; Pyrrolidines; RNA-Dependent RNA Polymerase; SARS-CoV-2 | 2020 |
Methyl Adenine Identification (MadID): High-Resolution Detection of Protein-DNA Interactions.
Topics: Adenine; Adenosine; Bacterial Proteins; Binding Sites; Chromatin; Chromatin Immunoprecipitation; DNA; DNA Methylation; DNA-Binding Proteins; HeLa Cells; High-Throughput Nucleotide Sequencing; Humans; In Situ Hybridization, Fluorescence; Optical Imaging; Protein Binding; Protein Interaction Mapping; Sequence Analysis, DNA; Site-Specific DNA-Methyltransferase (Adenine-Specific); Telomere | 2020 |
Interactions Between Remdesivir, Ribavirin, Favipiravir, Galidesivir, Hydroxychloroquine and Chloroquine with Fragment Molecular of the COVID-19 Main Protease with Inhibitor N3 Complex (PDB ID:6LU7) Using Molecular Docking.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Betacoronavirus; Binding Sites; Chloroquine; Coronavirus 3C Proteases; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Cysteine Endopeptidases; Drug Interactions; Humans; Hydrogen Bonding; Hydroxychloroquine; Ligands; Molecular Docking Simulation; Nanotechnology; Pandemics; Pneumonia, Viral; Protease Inhibitors; Pyrazines; Pyrrolidines; Ribavirin; SARS-CoV-2; Static Electricity; Viral Nonstructural Proteins | 2020 |
sgBE: a structure-guided design of sgRNA architecture specifies base editing window and enables simultaneous conversion of cytosine and adenosine.
Topics: Adenine; Adenosine; CRISPR-Associated Protein 9; CRISPR-Cas Systems; Cryoelectron Microscopy; Cytosine; Gene Editing; HEK293 Cells; High-Throughput Nucleotide Sequencing; Humans; Nucleotides; RNA, Guide, Kinetoplastida; Software | 2020 |
Effects of Extraction Temperature on Efficacy of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Aqueous Extract against Oxidative Stress.
Topics: Adenine; Adenosine; Animals; Antioxidants; Biological Products; Cell Death; Cell Line; Cytoprotection; Flavonoids; Glutathione; Glutathione Peroxidase; Hydrogen Peroxide; Mice; Oxidative Stress; Phenols; Reactive Oxygen Species; Reishi; Superoxide Dismutase; Temperature; Uracil | 2020 |
Inhibition of ecto-5'-nucleotidase and adenosine deaminase is able to reverse long-term behavioural effects of early ethanol exposure in zebrafish (Danio rerio).
Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Animals; Antisocial Personality Disorder; Behavior, Animal; Disease Models, Animal; Ethanol; Female; Humans; Pregnancy; Prenatal Exposure Delayed Effects; Social Interaction; Zebrafish | 2020 |
New Chemical Probe Targeting Bacterial NAD Kinase.
Topics: Adenine; Adenosine; Amino Acid Sequence; Animals; Anti-Bacterial Agents; Bacterial Proteins; Disease Models, Animal; Enzyme Inhibitors; Mice; Models, Molecular; NADP; Phosphotransferases (Alcohol Group Acceptor); Protein Conformation; Sepharose; Staphylococcus aureus | 2020 |
A Cas9-mediated adenosine transient reporter enables enrichment of ABE-targeted cells.
Topics: Adenine; Adenosine; Base Composition; CRISPR-Associated Protein 9; Gene Editing; Genes, Reporter; Humans; Luminescent Proteins; Pluripotent Stem Cells; Red Fluorescent Protein; Single-Cell Analysis | 2020 |
Morphologic assessment of hypertonic citrate adenine, histidine-tryptophan-ketoglutarate, and university of Wisconsin solutions for hypothermic uterus preservation in rats.
Topics: Adenine; Adenosine; Allopurinol; Animals; Citric Acid; Female; Glucose; Glutathione; Histidine; Insulin; Mannitol; Organ Preservation; Organ Preservation Solutions; Potassium Chloride; Raffinose; Rats; Tryptophan; Universities; Uterus; Wisconsin | 2021 |
Long living excited state of protonated adenosine unveiled by ultrafast fluorescence spectroscopy and density functional theoretical study.
Topics: Adenine; Adenosine; Density Functional Theory; Hydrogen-Ion Concentration; Spectrometry, Fluorescence | 2021 |
In silico evaluation of potential inhibitory activity of remdesivir, favipiravir, ribavirin and galidesivir active forms on SARS-CoV-2 RNA polymerase.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; COVID-19 Drug Treatment; Drug Repositioning; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Pyrazines; Pyrrolidines; Ribavirin; RNA, Viral; SARS-CoV-2 | 2022 |
Impaired airway epithelial barrier integrity was mediated by PI3Kδ in a mouse model of lipopolysaccharide-induced acute lung injury.
Topics: Acute Lung Injury; Adenine; Adenosine; Animals; Bronchoalveolar Lavage Fluid; Cadherins; Class I Phosphatidylinositol 3-Kinases; Claudins; Cytokines; Disease Models, Animal; Lipopolysaccharides; Lung; Male; Mice, Inbred BALB C; Quinazolines; Quinolines | 2021 |
Synthesis of Piperidine Nucleosides as Conformationally Restricted Immucillin Mimics.
Topics: Adenine; Adenosine; Magnetic Resonance Spectroscopy; Molecular Conformation; Nucleosides; Piperidines; Purine Nucleosides; Pyrimidinones; Pyrrolidines; Structure-Activity Relationship | 2021 |
End-labeling-based electrochemical strategy for detection of adenine methylation in nucleic acid by differential pulse voltammetry.
Topics: Adenine; Adenosine; Antibodies, Monoclonal; Armoracia; DNA; Electrochemical Techniques; Escherichia coli; Gold; HeLa Cells; Horseradish Peroxidase; Humans; Immobilized Nucleic Acids; Immunoglobulin G; Limit of Detection; Metal Nanoparticles; Methylation; Reproducibility of Results; RNA | 2021 |
Quantitative analysis of m
Topics: Adenine; Adenosine; Biochemical Phenomena; Chromatography, Liquid; Methylation; Nucleosides; RNA; RNA, Messenger; Tandem Mass Spectrometry | 2021 |
Effect of drug metabolism in the treatment of SARS-CoV-2 from an entirely computational perspective.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Chloroquine; COVID-19; COVID-19 Drug Treatment; Drug Design; Drug Discovery; Humans; Metabolic Networks and Pathways; Molecular Docking Simulation; Nitro Compounds; Pyrazines; Pyrrolidines; Ribavirin; SARS-CoV-2; Thiazoles | 2021 |
Survival-associated N
Topics: Adenine; Adenosine; Aged; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Databases, Genetic; Female; Gene Expression; Humans; Immunohistochemistry; Lung Neoplasms; Male; Methylation; Methyltransferases; Middle Aged; Principal Component Analysis; Prognosis; RNA, Messenger; ROC Curve; Survival Rate; Time Factors | 2021 |
Activity of Galidesivir in a Hamster Model of SARS-CoV-2.
Topics: Adenine; Adenosine; Animals; Antiviral Agents; Cell Line; COVID-19; COVID-19 Drug Treatment; Cricetinae; Disease Models, Animal; Humans; Lung; Mesocricetus; Pyrrolidines; SARS-CoV-2; Viral Load | 2021 |
Evaluation of the radical scavenging activity of some representative isoprenoid and aromatic cytokinin ribosides (N
Topics: Adenine; Adenosine; Antioxidants; Cytokinins; Glycosides; Terpenes | 2022 |
Quantitative analysis of 20 purine and pyrimidine metabolites by HILIC-MS/MS in the serum and hippocampus of depressed mice.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Animals; Chromatography, High Pressure Liquid; Hippocampus; Hypoxanthines; Inosine; Mice; Purines; Pyrimidines; Tandem Mass Spectrometry | 2022 |
Role of the Hydrogen Bond on the Internal Conversion of Photoexcited Adenosine.
Topics: Adenine; Adenosine; Hydrogen Bonding; Protons; Sugars | 2022 |
The dynamics of t1 adenosine binding on human Argonaute 2: Understanding recognition with conformational selection.
Topics: Adenine; Adenosine; Humans; Nucleotides; Protein Binding; RNA; RNA Interference; RNA, Messenger | 2022 |
Inhibition of adenosine deaminase activity reverses resistance to the cytotoxic effect of high adenosine levels in cervical cancer cells.
Topics: Adenine; Adenosine; Adenosine Deaminase; Antineoplastic Agents; Female; Humans; Papillomavirus Infections; Tumor Microenvironment; Uterine Cervical Neoplasms | 2022 |
Systematic Design of Adenosine Analogs as Inhibitors of a
Topics: Adenine; Adenosine; Animals; Clostridioides difficile; DNA; Humans; Mammals; Methyltransferases; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine | 2023 |
TadA orthologs enable both cytosine and adenine editing of base editors.
Topics: Adenine; Adenosine; CRISPR-Cas Systems; Cytosine; DNA; Gene Editing; RNA | 2023 |
Enriching adenosine by thymine-rich DNA oligomers.
Topics: Adenine; Adenosine; DNA; Nucleic Acid Conformation; Thymine | 2023 |
Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a
Topics: Adenine; Adenosine; Clostridioides difficile; Clostridium Infections; DNA; Methyltransferases; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific) | 2023 |
Structure-guided optimization of adenosine mimetics as selective and potent inhibitors of coronavirus nsp14 N7-methyltransferases.
Topics: Adenine; Adenosine; Antiviral Agents; COVID-19; Humans; Methyltransferases; Pandemics; RNA, Viral; S-Adenosylmethionine; SARS-CoV-2; Viral Nonstructural Proteins | 2023 |
Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Humans; Muscle, Skeletal; Nucleotides; Rabbits; Ryanodine Receptor Calcium Release Channel | 2023 |
Components of the Nucleotide Salvage Pathway Increase Frog Virus 3 (FV3) Replication.
Topics: Adenine; Adenosine; Animals; Inosine; Nucleotides; Purines; Ranavirus | 2023 |
Enhanced production of cordycepin under solid-state fermentation of Cordyceps militaris by using combinations of grains/substrates.
Topics: Adenine; Adenosine; Cellulose; Cordyceps; Edible Grain; Fermentation; Humans; Saccharum | 2023 |