adenine has been researched along with adenosine kinase in 57 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (42.11) | 18.7374 |
| 1990's | 16 (28.07) | 18.2507 |
| 2000's | 12 (21.05) | 29.6817 |
| 2010's | 5 (8.77) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Livshits, VA | 1 |
| Hershfield, MS; Seegmiller, JE; Snyder, FF | 3 |
| Cohen, A; Gudas, LJ; Martin, DW; Ullman, B | 1 |
| Hovi, T; Raivio, KO | 1 |
| Hershfield, MS; Seegmiller, JE | 1 |
| Buttin, G; Debatisse, M | 1 |
| Berne, RM; Coleman, SD; Ely, SW; Matherne, GP | 1 |
| Paglia, DE; Valentine, WN | 1 |
| de Jong, JW; Den Boer, PJ; Grootegoed, JA; Mackenbach, P | 1 |
| Bowditch, J; Brown, AK; Dow, JW; Nigdikar, SV | 1 |
| Bingham, H; Chan, VL; Du, RP; Juranka, P; Pang, JC | 1 |
| Meghji, P; Middleton, KM; Newby, AC | 1 |
| Holmes, EW; Manfredi, JP | 1 |
| Avila, A; Avila, JL | 1 |
| Abarzua, M; Davis, JA; Lawton, A; Weinberg, JM | 1 |
| Allan, PW; Bennett, LL; Brockman, RW; Rose, LM; Shaddix, SC | 1 |
| Gerber, G; Rapoport, I; Rapoport, SM | 1 |
| Archer, S; Chan, VL; Ho, JH; Juranka, PF | 1 |
| Miras-Portugal, MT; Rotllán, P | 1 |
| Chiba, P; Kraupp, M; Müller, MM; Rumpold, H | 1 |
| Green, RD | 1 |
| Martin, TF; Ronning, SA | 1 |
| Baird-Lambert, JA; Davies, LP; Jamieson, DD; Kazlauskas, R | 1 |
| Guranowski, A; Wasternack, C | 1 |
| Berry, M; Buttin, G; Debatisse, M | 1 |
| Corsi, C; Fratti, S; Pazzagli, M; Pedata, F; Pepeu, G | 1 |
| Seymour, AM; Smolenski, RT; Yacoub, MH | 1 |
| Fredholm, BB; Lloyd, HG | 1 |
| Connelly, MC; Fridland, A; Marshall, DR; Robbins, BL; Srinivas, RV | 1 |
| Bianchi, V; Bonvini, P; Borella, S; Ferraro, P; Reichard, P | 1 |
| Sciotti, VM; Van Wylen, DG | 1 |
| Barankiewicz, J; Mitchell, BS; Spychala, J | 1 |
| Dubey, RK; Gillespie, DG; Jackson, EK; Mi, Z | 1 |
| Kalsi, KK; Kochan, Z; Smolenski, RT; Yacoub, MH; Zych, M | 1 |
| Manthei, SA; Reiling, CM; Van Wylen, DG | 1 |
| Kalsi, K; Kochan, Z; Smolenski, RT; Yacoub, MH; Zych, M | 1 |
| IJzerman, AP; Pavan, B | 1 |
| Deussen, A; Kelm, M; Schäfer, S; Stappert, M | 1 |
| Dubey, RK; Gillespie, DG; Jackson, EK; Shue, H | 1 |
| Barry, CP; Lind, SE | 1 |
| Cerniway, RJ; Headrick, JP; Matherne, GP; Peart, J | 1 |
| Abunasra, H; Jayakumar, J; Kalsi, KK; Raisky, O; Slominska, EM; Smolenski, RT; Suzuki, K; Yacoub, MH | 1 |
| Gray, CC; Kalsi, KK; Kochan, Z; Smolenski, RT; Yacoub, MH; Zych, M | 1 |
| Abunasra, H; Jayakumar, J; Kalsi, KK; Raisky, O; Smolenski, RT; Suzuki, K; Yacoub, MH | 1 |
| Benton, HP; Kollias-Baker, C; MacDonald, MH; Tesch, AM | 1 |
| Dolezel, P; Mlejnek, P | 1 |
| Kenanov, D; Schuster, S | 1 |
| Chambers, MG; Mason, RM; Mistry, D | 1 |
| Long, MC; Parker, WB | 1 |
| Fijolek, A; Hofer, A; Mäser, P; Mosimann, M; Rofougaran, R; Vodnala, M | 1 |
| Boison, D; Li, T; Shen, HY | 1 |
| Bourderioux, A; Brynda, J; Dostál, J; Dušek, M; Dvořáková, H; Džubák, P; Fanfrlík, J; Hajdúch, M; Hnízda, A; Hocek, M; Konečný, P; Nauš, P; Pichová, I; Pohl, R; Rezáčová, P; Snášel, J; Stolaříková, J; Veverka, V; Votruba, I; Zábranská, H | 1 |
| Moretto, MB; Oliveira, MC; Pimentel, VC; Schetinger, MR; Sebastião, AM; Zanini, D | 1 |
| Ito, S; Kon, Y; Otsuguro, K; Otsuka, S; Tomonari, Y; Yamaguchi, S | 1 |
| Alzahrani, KJH; de Koning, HP; Ebiloma, GU; Hofer, A; Ranjbarian, F; Vodnala, M | 1 |
2 review(s) available for adenine and adenosine kinase
| Article | Year |
|---|---|
Red cell metabolism, normal and abnormal implications for red cell aging.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Kinase; Adenosine Monophosphate; Anemia, Hemolytic; Energy Metabolism; Erythrocyte Aging; Erythrocytes; Erythrocytes, Abnormal; Glycolysis; Hematologic Diseases; Humans | 1991 |
Purine salvage pathways in myocardium.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Adenosine Kinase; Adenosine Monophosphate; Animals; Guanine; Guanosine; Guanosine Monophosphate; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine Monophosphate; Myocardium; Purine Nucleosides; Purine Nucleotides | 1985 |
55 other study(ies) available for adenine and adenosine kinase
| Article | Year |
|---|---|
[Effect of 2,6-diaminopurine resistance mutations on adenine and adenosine assimilation by cells of an adenine-dependent strain of Escherichia coli K-12].
Topics: Adenine; Adenosine; Adenosine Kinase; Escherichia coli; Mutation; Phosphotransferases; Purines; Recombination, Genetic | 1976 |
Adenine and adenosine are toxic to human lymphoblast mutants defective in purine salvage enzymes.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Cell Line; Humans; Hypoxanthine Phosphoribosyltransferase; Lymphocytes; Nucleotides; Pentosyltransferases; Phosphotransferases | 1977 |
Analysis of adenosine-mediated pyrimidine starvation using cultured wild-type and mutant mouse T-lymphoma cells.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Azepines; Cell Line; Cells, Cultured; Deoxyribonucleosides; Hypoxanthine Phosphoribosyltransferase; Lymphoma, Non-Hodgkin; Mice; Mutation; Phosphoribosyl Pyrophosphate; Pyrimidines; T-Lymphocytes | 1978 |
Purine reutilization in phytohemagglutinin-stimulated human T-lymphocytes.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Adenosine Deaminase; Adenosine Kinase; Guanine; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Kinetics; Lectins; Lymphocyte Activation; Nucleotides; T-Lymphocytes | 1978 |
Cytotoxic and metabolic effects of adenosine and adenine on human lymphoblasts.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Azepines; Cell Division; Humans; Lymphocytes; Phosphoribosyl Pyrophosphate; Pyrimidine Nucleotides; Ribonucleosides; Uridine | 1978 |
Coordinate regulation of the proximal and distal steps of the pathway of purine synthesis de nono in WI-L2 human lymphoblasts.
Topics: Adenine; Adenine Nucleotides; Adenosine Kinase; Azaserine; Cell Line; Feedback; Formates; Guanine; Hypoxanthines; Inosine Nucleotides; Kinetics; Ligases; Lymphocytes; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Purines; Thioinosine | 1977 |
Purine toxicity in human lymphoblasts.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Cell Division; Cell Line; Drug Synergism; Glucose; Hypoxanthines; Lymphocytes; Mutation; Phosphoribosyl Pyrophosphate; Purines; Ribonucleotides; Uridine | 1977 |
The control of cell proliferation by preformed purines: a genetic study. II. Pleiotropic manifestations and mechanism of a control exerted by adenylic purines on PRPP synthesis.
Topics: Adenine; Adenosine; Adenosine Kinase; Anti-Bacterial Agents; Azepines; Cell Line; Hypoxanthine Phosphoribosyltransferase; Mutation; Pentosephosphates; Phosphoribosyl Pyrophosphate; Ribonucleosides | 1977 |
Inhibition of adenosine metabolism increases myocardial interstitial adenosine concentrations and coronary flow.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Coronary Circulation; Extracellular Space; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Myocardium; Perfusion; Tubercidin; Vascular Resistance | 1992 |
Effects of glucose and adenosine on the ATP content of hamster spermatids.
Topics: Adenine; Adenosine; Adenosine Kinase; Adenosine Triphosphate; Animals; Cricetinae; Cyclic AMP; Dipyridamole; Dose-Response Relationship, Drug; Fructose; Galactose; Glucose; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Male; Mannose; Spermatids; Tubercidin | 1990 |
Salvage mechanisms for regeneration of adenosine triphosphate in rat cardiac myocytes.
Topics: Adenine; Adenosine; Adenosine Kinase; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Female; Kinetics; Myocardium; Phosphoribosyl Pyrophosphate; Rats; Rats, Inbred Strains | 1987 |
Imbalance of purine nucleotides in alanosine-resistant baby hamster kidney cells.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Kinase; Adenylosuccinate Lyase; Adenylosuccinate Synthase; Alanine; Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Cricetinae; Culture Media; Humans; Hypoxanthine Phosphoribosyltransferase; Mutation; Phosphotransferases; Purines; Selection, Genetic; Transformation, Genetic; Uridine | 1989 |
Absolute rates of adenosine formation during ischaemia in rat and pigeon hearts.
Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Deaminase; Adenosine Kinase; Adult; AMP Deaminase; Animals; Columbidae; Coronary Disease; Female; Heart; Histocytochemistry; Humans; Male; Middle Aged; Myocardium; Nucleotidases; Nucleotides; Phosphoric Monoester Hydrolases; Rats; Rats, Inbred Strains; Species Specificity; Tubercidin | 1988 |
Defective transport of pyrazolopyrimidine ribosides in insensitive Trypanosoma cruzi wild strains is a parasite-stage specific and reversible characteristic.
Topics: Adenine; Adenosine; Adenosine Kinase; Animals; Antiprotozoal Agents; Biological Transport; Drug Resistance; Formycins; Kinetics; Phosphotransferases; Pyrimidine Nucleosides; Trypanosoma cruzi | 1987 |
Modulation of cell nucleotide levels of isolated kidney tubules.
Topics: Adenine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Adenosine Triphosphate; Animals; Biomechanical Phenomena; Extracellular Space; Female; Glycerophosphates; In Vitro Techniques; Kidney Tubules; Nucleosides; Nucleotides; Purines; Rabbits | 1988 |
Alterations in nucleotide pools induced by 3-deazaadenosine and related compounds. Role of adenylate deaminase.
Topics: Adenine; Adenosine Kinase; Alanine; Aminoglycosides; AMP Deaminase; Animals; Anti-Bacterial Agents; Cell Survival; Coformycin; Hypoxanthine; Hypoxanthines; Mice; Nucleotide Deaminases; Nucleotides; Time Factors; Tubercidin | 1988 |
Degradation of AMP in erythrocytes of man. Evidence for a cytosolic phosphatase activity.
Topics: Acid Phosphatase; Adenine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Adenosine Monophosphate; Chromatography, Gel; Coformycin; Cytosol; Deoxyadenosines; Erythrocytes; Humans; Hydrogen-Ion Concentration | 1987 |
An analysis of multiple mechanisms of adenosine toxicity in baby hamster kidney cells.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Cell Adhesion; Cell Line; Coformycin; Drug Resistance; Drug Synergism; Guinea Pigs; Homocysteine; Kidney; Nucleotides; Pentostatin; Ribonucleotide Reductases; S-Adenosylhomocysteine; Uridine | 1985 |
Purine nucleotide synthesis in adrenal chromaffin cells.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Adenosine Deaminase; Adenosine Kinase; Adrenal Glands; Animals; Cattle; Chromaffin System; Formates; Glycine; Hypoxanthine Phosphoribosyltransferase; Male; Purine Nucleotides | 1985 |
Regulation of purine uptake in normal and neoplastic cells.
Topics: 5'-Nucleotidase; Adenine; Adenosine Kinase; Cell Line; Erythrocytes; Granulocytes; Humans; Kinetics; Leukemia, Experimental; Nucleotidases; Pentosyltransferases; Purine Nucleosides; Purine Nucleotides; Purines | 1983 |
Adenosine transport by a variant of C1300 murine neuroblastoma cells deficient in adenosine kinase.
Topics: Adenine; Adenosine; Adenosine Kinase; Animals; Biological Transport; Cell Line; Genetic Variation; Kinetics; Mice; Neuroblastoma; Phosphotransferases; Purines; Structure-Activity Relationship | 1980 |
Multiple mechanisms of growth inhibition by cyclic AMP derivatives in rat GH1 pituitary cells: isolation of an adenylate cyclase-deficient variant.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Adenosine Kinase; Adenylyl Cyclases; Animals; Bucladesine; Cell Division; Cell Line; Clone Cells; Cyclic AMP; Pituitary Gland; Rats | 1981 |
Halogenated pyrrolopyrimidine analogues of adenosine from marine organisms: pharmacological activities and potent inhibition of adenosine kinase.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Adenosine; Adenosine Kinase; Adenylyl Cyclases; Animals; Brain; Bronchodilator Agents; Cardiovascular System; Central Nervous System; Guinea Pigs; In Vitro Techniques; Male; Marine Biology; Mice; Phosphotransferases; Rats; Ribonucleosides; Theophylline; Tubercidin | 1984 |
Adenine and adenosine metabolizing enzymes in cell-free extracts from Euglena gracilis.
Topics: Acid Phosphatase; Adenine; Adenine Phosphoribosyltransferase; Adenosine; Adenosine Kinase; Aminohydrolases; Euglena gracilis; Kinetics; Purine-Nucleoside Phosphorylase; Thionucleosides | 1982 |
The potentiation of adenine toxicity to Chinese hamster cells by coformycin: suppression in mutants with altered regulation of purine biosynthesis or increased adenylate-deaminase activity.
Topics: Adenine; Adenosine Kinase; AMP Deaminase; Animals; Cell Line; Coformycin; Cricetinae; Drug Synergism; Fibroblasts; Inosine Monophosphate; Mutation; Nucleotide Deaminases; Purines; Ribonucleosides; Temperature | 1981 |
Regulation of extracellular adenosine levels in the striatum of aging rats.
Topics: 2-Amino-5-phosphonovalerate; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Aging; Amino Acids; Animals; Corpus Striatum; Enzyme Inhibitors; Extracellular Space; Male; Microdialysis; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tubercidin | 1995 |
Hyperthyroidism increases adenosine transport and metabolism in the rat heart.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Kinase; Adenosylhomocysteinase; AMP Deaminase; Animals; Biological Transport; Body Weight; Disease Models, Animal; Heart; Hydrolases; Hyperthyroidism; Male; Myocardium; Nucleotidases; Organ Size; Phosphorylation; Purine-Nucleoside Phosphorylase; Rats; Thyroxine; Time Factors; Xanthine Oxidase | 1995 |
Involvement of adenosine deaminase and adenosine kinase in regulating extracellular adenosine concentration in rat hippocampal slices.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Basal Metabolism; Electric Stimulation; Hippocampus; In Vitro Techniques; Male; Purines; Rats; Tubercidin | 1995 |
A human T lymphoid cell variant resistant to the acyclic nucleoside phosphonate 9-(2-phosphonylmethoxyethyl)adenine shows a unique combination of a phosphorylation defect and increased efflux of the agent.
Topics: Adenine; Adenosine Kinase; Antiviral Agents; Biological Transport; Cell Line; Deoxycytidine Kinase; Drug Resistance; Humans; Organophosphonates; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); T-Lymphocytes | 1995 |
Effects of mutational loss of nucleoside kinases on deoxyadenosine 5'-phosphate/deoxyadenosine substrate cycle in cultured CEM and V79 cells.
Topics: Adamantane; Adenine; Adenosine; Adenosine Kinase; Animals; Cell Division; Cell Line; Cricetinae; Deoxyadenosines; Deoxycytidine; Deoxycytidine Kinase; Deoxyribonucleotides; DNA; Fibroblasts; Humans; Hypoxanthine; Hypoxanthines; Kinetics; Lymphocytes; Thymidine; Time Factors; Tritium | 1994 |
Increases in interstitial adenosine and cerebral blood flow with inhibition of adenosine kinase and adenosine deaminase.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Brain; Cerebrovascular Circulation; Dialysis Solutions; Dose-Response Relationship, Drug; Extracellular Space; Hypoxanthine; Hypoxanthines; Inosine; Male; Rats; Rats, Wistar; Tubercidin | 1993 |
Adenosine metabolism during phorbol myristate acetate-mediated induction of HL-60 cell differentiation: changes in expression pattern of adenosine kinase, adenosine deaminase, and 5'-nucleotidase.
Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Deaminase; Adenosine Kinase; B-Lymphocytes; Cell Differentiation; Extracellular Space; Gene Expression Regulation, Enzymologic; HL-60 Cells; Humans; Hypoxanthine; Purines; RNA, Messenger; Stress, Physiological; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1997 |
Exogenous and endogenous adenosine inhibits fetal calf serum-induced growth of rat cardiac fibroblasts: role of A2B receptors.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Adenosine-5'-(N-ethylcarboxamide); Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Cattle; Cell Division; Culture Media; Dipyridamole; DNA Replication; Enzyme Inhibitors; Fibroblasts; Heart; Male; Myocardium; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Tubercidin; Xanthines | 1997 |
Adenine/ribose supply increases adenosine production and protects ATP pool in adenosine kinase-inhibited cardiac cells.
Topics: Adenine; Adenosine; Adenosine Kinase; Adenosine Triphosphate; Animals; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Heart; In Vitro Techniques; Kinetics; Male; Myocardium; Purines; Rats; Rats, Sprague-Dawley; Ribose; Tubercidin; Uridine | 1998 |
Dual cardiac microdialysis to assess drug-induced changes in interstitial purine metabolites: adenosine deaminase inhibition versus adenosine kinase inhibition.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Chromatography, High Pressure Liquid; Extracellular Space; Hypoxanthine; Inosine; Male; Microdialysis; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Rabbits; Tubercidin | 1998 |
Effects of adenine/ribose supply on adenosine production and ATP concentration in adenosine kinase inhibited cardiac cells.
Topics: Adenine; Adenosine; Adenosine Kinase; Adenosine Triphosphate; Animals; Cells, Cultured; Endothelium, Vascular; Heart; Kinetics; Myocardium; Rats; Rats, Sprague-Dawley; Ribose | 1998 |
Processing of adenosine receptor agonists in rat and human whole blood.
Topics: Adenine; Adenosine; Adenosine Kinase; Aminohydrolases; Animals; Blood; Deoxyadenosines; Enzyme Inhibitors; Humans; Purinergic P1 Receptor Agonists; Rats; Thioinosine | 1998 |
Quantification of extracellular and intracellular adenosine production: understanding the transmembranous concentration gradient.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Biological Transport; Bradykinin; Coronary Circulation; Cytosol; Depression, Chemical; Dipyridamole; Drug Synergism; Enzyme Inhibitors; Extracellular Space; Guinea Pigs; Heart; Models, Biological; Myocardium; Osmolar Concentration; Oxygen; Oxygen Consumption; Piperazines; Thioinosine; Tubercidin | 1999 |
A(2B) receptors mediate antimitogenesis in vascular smooth muscle cells.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Kinase; Adenosine-5'-(N-ethylcarboxamide); Animals; Anticoagulants; Antihypertensive Agents; Aorta, Abdominal; Becaplermin; Cell Division; Dinucleoside Phosphates; Enzyme Inhibitors; Hyperplasia; Male; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Oligonucleotides, Antisense; Phenethylamines; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-2; Thymidine; Tritium; Tubercidin; Vasodilator Agents; Xanthines | 2000 |
Adenosine-mediated killing of cultured epithelial cancer cells.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Apoptosis; Breast Neoplasms; Carcinoma, Squamous Cell; Cell Division; Cell Survival; Coformycin; Deoxyadenosines; Dipyridamole; Enzyme Inhibitors; Female; Humans; Kinetics; Ovarian Neoplasms; Pentostatin; Tumor Cells, Cultured | 2000 |
Cardioprotection with adenosine metabolism inhibitors in ischemic-reperfused mouse heart.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Enzyme Inhibitors; Female; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Perfusion; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Tubercidin | 2001 |
Protection from reperfusion injury after cardiac transplantation by inhibition of adenosine metabolism and nucleotide precursor supply.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Cardioplegic Solutions; Creatinine; Deoxyadenosines; Enzyme Inhibitors; Heart Transplantation; In Vitro Techniques; Inflammation; Male; Myocardial Reperfusion Injury; Myocardium; Neutrophil Infiltration; Perfusion; Rats; Rats, Sprague-Dawley; Ribose; Treatment Outcome | 2001 |
The effect of adenosine metabolism inhibition and nucleotide precursor supply on adenosine production in human heart endothelial cells.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Adenosine Triphosphate; Cells, Cultured; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; Humans; Nucleotides; Pentostatin; Phosphates; Ribose; Tubercidin | 2000 |
Enhanced endogenous adenosine production and protection of the heart after transplantation.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Adenosine Triphosphate; Animals; Guanosine Triphosphate; Heart; Heart Transplantation; Myocardium; Rats; Ribose | 2000 |
Effects of an adenosine kinase inhibitor and an adenosine deaminase inhibitor on accumulation of extracellular adenosine by equine articular chondrocytes.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Cartilage, Articular; Chondrocytes; Enzyme Inhibitors; Horses; Lipopolysaccharides; Nitric Oxide; Nitrites; Tubercidin | 2002 |
Apoptosis induced by N6-substituted derivatives of adenosine is related to intracellular accumulation of corresponding mononucleotides in HL-60 cells.
Topics: Adenine; Adenine Nucleotides; Adenine Phosphoribosyltransferase; Adenosine; Adenosine Kinase; Adenosine Monophosphate; Amino Acid Chloromethyl Ketones; Apoptosis; Caspase 3; Caspase Inhibitors; Caspases; Enzyme Inhibitors; HL-60 Cells; Humans; Phosphorylation | 2005 |
Adenine and adenosine salvage pathways in erythrocytes and the role of S-adenosylhomocysteine hydrolase. A theoretical study using elementary flux modes.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Kinase; Adenosine Triphosphate; Adenosylhomocysteinase; ADP Ribose Transferases; Erythrocytes; Humans; Metabolic Diseases; Models, Biological; Purine-Nucleoside Phosphorylase | 2005 |
The role of adenosine in chondrocyte death in murine osteoarthritis and in a murine chondrocyte cell line.
Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Apoptosis; Cartilage, Articular; Cell Death; Cell Line; Chondrocytes; DNA Fragmentation; Enzyme Inhibitors; Homocysteine; Male; Mice; Mice, Inbred Strains; Osteoarthritis; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; Tubercidin | 2006 |
Structure-activity relationship for nucleoside analogs as inhibitors or substrates of adenosine kinase from Mycobacterium tuberculosis. I. Modifications to the adenine moiety.
Topics: Adenine; Adenosine Kinase; Enzyme Inhibitors; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Structure-Activity Relationship | 2006 |
Adenosine kinase mediates high affinity adenosine salvage in Trypanosoma brucei.
Topics: Adenine; Adenosine Kinase; Animals; Antimetabolites; Catalysis; Guanosine Triphosphate; Humans; Leishmania donovani; Membrane Transport Proteins; Protozoan Proteins; Recombinant Proteins; Substrate Specificity; Trypanosoma brucei brucei; Trypanosomiasis, African; Vidarabine | 2008 |
A novel mouse model for sudden unexpected death in epilepsy (SUDEP): role of impaired adenosine clearance.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Caffeine; Cause of Death; Death, Sudden; Disease Models, Animal; Enzyme Inhibitors; Epilepsy; Kainic Acid; Mice; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Risk Factors; Seizures; Survival Analysis; Tubercidin | 2010 |
Structural basis for inhibition of mycobacterial and human adenosine kinase by 7-substituted 7-(Het)aryl-7-deazaadenine ribonucleosides.
Topics: Adenine; Adenosine Kinase; Adenosine Triphosphate; Antitubercular Agents; Binding Sites; Crystallography, X-Ray; Drug Evaluation, Preclinical; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Ribonucleosides; Structure-Activity Relationship | 2014 |
Neuroinflammation after neonatal hypoxia-ischemia is associated with alterations in the purinergic system: adenosine deaminase 1 isoenzyme is the most predominant after insult.
Topics: Acetylglucosaminidase; Adenine; Adenosine Deaminase; Adenosine Kinase; Animals; Animals, Newborn; Blotting, Western; Brain; Cerebral Cortex; Hypoxia-Ischemia, Brain; Inflammation; Isoenzymes; Male; Peroxidase; Purines; Rats, Wistar; Receptor, Adenosine A1 | 2015 |
An adenosine kinase inhibitor, ABT-702, inhibits spinal nociceptive transmission by adenosine release via equilibrative nucleoside transporters in rat.
Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine Deaminase; Adenosine Kinase; Analgesics; Animals; Animals, Newborn; Enzyme Inhibitors; Membrane Potentials; Morpholines; Motor Neurons; Neural Pathways; Nociceptive Pain; Pyrimidines; Reflex; Spinal Cord; Tissue Culture Techniques; Xanthines | 2015 |
9-(2'-Deoxy-2'-Fluoro-β-d-Arabinofuranosyl) Adenine Is a Potent Antitrypanosomal Adenosine Analogue That Circumvents Transport-Related Drug Resistance.
Topics: Adenine; Adenosine Kinase; Animals; Antimetabolites; Drug Resistance; Mice; Purine-Nucleoside Phosphorylase; Trypanosoma; Trypanosoma brucei brucei; Trypanosomiasis, African | 2017 |