adenine has been researched along with 9-(2,3-dihydroxypropyl)adenine in 53 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 28 (52.83) | 18.7374 |
1990's | 9 (16.98) | 18.2507 |
2000's | 7 (13.21) | 29.6817 |
2010's | 9 (16.98) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Carlson, EE; Goswami, M; Wilke, KE | 1 |
De Clercq, E; Holy, A | 1 |
Holý, A; Kára, J; Vácha, P | 1 |
Cools, M; De Clercq, E | 3 |
Alba, AP; De Clercq, E; De Fazio, G; Vicente, M | 1 |
Nĕmec, V; Sláma, K | 1 |
DeClercq, E; Lin, JC; Pagano, JS | 1 |
Frost, N; Herrmann, G; Jennrich, H; Reefschläger, J | 1 |
De Clercq, E; Kitaoka, S; Konno, T | 1 |
Doskocil, M; Holý, A; Jelínek, R | 1 |
Holý, A; Schuster, G | 1 |
Seichert, V | 1 |
De Clercq, E; Durbin, RK; Stollar, V | 1 |
De Clercq, E; De Fazio, G; Vicente, M | 1 |
De Clercq, E; Gil-Fernández, C | 1 |
Holý, A; Sodja, I | 1 |
Dragún, M; Holý, A; Rada, B; Votruba, I | 1 |
Gresíková, M; Holý, A; Rada, B | 1 |
Dragún, M; Holý, A; Rada, B | 1 |
De Clercq, E; Holý, A; Votruba, I | 1 |
Holý, A; Rada, B | 1 |
de Clercq, E | 2 |
Barnett, BB; Clark, SM; Sidwell, RW; Smee, DF; Spendlove, RS | 2 |
Dzhavadova, GM; Gurskaia, GV; Tsilevich, TL; Vasil'ev, DG; Zavgorodniĭ, SG | 1 |
Beránek, J; Havlas, Z; Hrebabecký, H | 1 |
Cihák, A; Holý, A | 1 |
De Clercq, E; De Somer, P; Holý, A; Leyten, R; Matousek, J; Sobis, H | 1 |
Holý, A; Jelínek, R; Votruba, I | 1 |
Bezdĕk, M; Holý, A; Koukalová, B; Kovarík, A | 1 |
Gelbic, I; Marec, F | 1 |
Dominici, P; Moore, PS; Voltattorni, CB | 1 |
Fojtová, M; Holý, A; Kovarík, A; Votruba, I | 1 |
Gotoh, T; Hayashi, M; Hiraoka, A; Hosoya, A; Kitade, Y; Mori, K; Nakanishi, M; Yatome, C | 1 |
Bezdek, M; Fulnecek, J; Kovarík, A; Matyásek, R | 1 |
Depicker, A; Holý, A; Kovarík, A; Van Houdt, H | 1 |
Bezdek, M; Koukalová, B; Kovarík, A; Leitch, AR; Lichtenstein, CP; Lim, KY; Matyásek, R | 1 |
Tao, PZ; Wang, GX; Wang, L; Zhang, T; Zhao, ZZ | 1 |
Lu, MH; Tan, DM; Xiong, HE | 1 |
Fujita, K; Kiso, T; Ping, X; Tanaka, T; Taniguchi, M | 1 |
Ctrnáctá, V; Hrdý, I; Keithly, JS; Stejskal, F | 1 |
Cristani, C; D'Anna, F; Panattoni, A; Triolo, E | 1 |
Ctrnáctá, V; Fritzler, JM; Hrdý, I; Stejskal, F; Surinová, M; Zhu, G | 1 |
Fulneček, J; Holý, A; Kovařík, A; Křížová, K; Matyášek, R; Votruba, I | 1 |
Bittová, M; Fajkus, J; Fojtová, M; Majerová, E; Mozgová, I | 1 |
Frantík, E; Králík, A; Krouželka, J; Linhart, I; Mikeš, P; Mráz, J; Sístek, V | 1 |
Blažek, J; Brabcová, J; Janská, L; Krečmerová, M; Zarevúcka, M | 1 |
Baddorf, AP; Bonnesen, PV; Fuentes-Cabrera, M; James Cleaves Ii, H; Maksymovych, P; Pan, M; Rangel, E; Sanchez-Castillo, A; Sumpter, BG; Vallejo, E; Wang, J | 1 |
Blažek, J; Brabcová, J; Krečmerová, M; Palomo, JM; Vondrášek, J; Zarevúcka, M | 1 |
Chen, D; Cheng, Z; Fan, X; Fang, L; Hou, X; Wang, Z; Zhang, W | 1 |
2 review(s) available for adenine and 9-(2,3-dihydroxypropyl)adenine
Article | Year |
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Nucleoside analogues as antiviral agents.
Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Arabinonucleosides; Bromodeoxyuridine; Chemical Phenomena; Chemistry; Cytarabine; Deoxyuridine; Guanine; Herpesviridae Infections; Humans; Idoxuridine; Nucleosides; Ribavirin; Thymidine; Virus Diseases; Viruses | 1981 |
The discovery of antiviral agents: ten different compounds, ten different stories.
Topics: Acyclovir; Adenine; Antiviral Agents; Benzodiazepines; Benzylamines; Cidofovir; Cyclams; Cytosine; Heterocyclic Compounds; Humans; Imidazoles; Nucleosides; Organophosphonates; Tenofovir; Valacyclovir; Valine; Virus Diseases | 2008 |
51 other study(ies) available for adenine and 9-(2,3-dihydroxypropyl)adenine
Article | Year |
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Rational Design of Selective Adenine-Based Scaffolds for Inactivation of Bacterial Histidine Kinases.
Topics: Adenine; Adenosine Triphosphate; Anti-Bacterial Agents; Aspartic Acid; Bacteria; Drug Design; Histidine Kinase; HSP90 Heat-Shock Proteins; Models, Molecular; Molecular Docking Simulation; Structure-Activity Relationship | 2017 |
Antiviral activity of aliphatic nucleoside analogues: structure-function relationship.
Topics: Adenine; Antiviral Agents; Cytopathogenic Effect, Viral; Purines; Pyrimidines; Stereoisomerism; Structure-Activity Relationship; Vaccinia virus; Vesicular stomatitis Indiana virus | 1979 |
9-(S)-(2,3-Dihydroxypropyl)adenine inhibits the transformation of chick embryo fibroblasts infected with Rous sarcoma virus: Evidence for inhibition of enzymatic activity of isolated cellular protein kinases by the drug.
Topics: Adenine; Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Cells, Cultured; Chick Embryo; Fibroblasts; L-Lactate Dehydrogenase; Protein Kinases | 1979 |
Influence of S-adenosylhomocysteine hydrolase inhibitors on S-adenosylhomocysteine and S-adenosylmethionine pool levels in L929 cells.
Topics: Adenine; Adenosylhomocysteinase; Animals; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Hydrolases; L Cells; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine; Structure-Activity Relationship; Vaccinia virus | 1990 |
Antiviral activity of S-adenosylhomocysteine hydrolase inhibitors against plant viruses.
Topics: Adenine; Adenosylhomocysteinase; Animals; Antiviral Agents; Enzyme-Linked Immunosorbent Assay; Hydrolases; Phenylbutyrates; Plant Diseases; Plant Viruses; Rabbits; Tobacco Mosaic Virus; Virus Replication | 1990 |
Inhibition of phosphatase by open-chain nucleoside analogues in insects.
Topics: Acid Phosphatase; Adenine; Alkaline Phosphatase; Animals; Female; Hemiptera; Intestines; Malpighian Tubules; Nitrophenols; Organophosphorus Compounds; Phosphoric Monoester Hydrolases | 1989 |
Correlation between the antiviral activity of acyclic and carbocyclic adenosine analogues in murine L929 cells and their inhibitory effect on L929 cells S-adenosylhomocysteine hydrolase.
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Animals; Antiviral Agents; Cell Line; Fibroblasts; Hydrolases; Kinetics; Mice; Vaccinia virus; Vesicular stomatitis Indiana virus; Virus Replication | 1989 |
Novel acyclic adenosine analogs inhibit Epstein-Barr virus replication.
Topics: Adenine; Adenosine; Antimetabolites; Antiviral Agents; Cell Line; Cell Survival; DNA, Viral; Herpesvirus 4, Human; Organophosphonates; Organophosphorus Compounds; Virus Replication | 1987 |
Anti-herpes simplex virus and cytostatic activity of some new 5-substituted 1-(4-hydroxybutyl)-and 1-(2-hydroxyethoxymethyl) uracil nucleoside analogues.
Topics: Acyclovir; Adenine; Animals; Antimetabolites; Antiviral Agents; Cell Division; Cells, Cultured; Cricetinae; Humans; Simplexvirus; Structure-Activity Relationship; Uridine; Virus Replication | 1985 |
Antiviral potency of adenosine analogues: correlation with inhibition of S-adenosylhomocysteine hydrolase.
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Antibiotics, Antineoplastic; Antiviral Agents; Hydrolases; Kinetics; Measles virus; Reoviridae; Tubercidin; Vaccinia virus; Vesicular stomatitis Indiana virus; Virus Replication | 1985 |
Comparative efficacy of broad-spectrum antiviral agents as inhibitors of rotavirus replication in vitro.
Topics: Adenine; Adenosine; Amides; Antiviral Agents; Cell Line; Cytidine; Dose-Response Relationship, Drug; Pyrazoles; Ribavirin; Ribonucleosides; Ribose; Rotavirus; Tubercidin; Vidarabine; Virus Replication | 1986 |
Microscopic-anatomical changes in the chick embryo after administration of 9-(RS)-(2,3-dihydroxypropyl) adenine.
Topics: Abnormalities, Drug-Induced; Adenine; Animals; Chick Embryo; Eye Abnormalities; Limb Deformities, Congenital; Spinal Cord; Teratogens | 1987 |
Inhibitory effects of 9-(2,3-dihydroxypropyl)adenine and 3-(adenin-9-yl)-2-hydroxypropanoic acid 2-methylpropylester on potato virus X replication.
Topics: Adenine; Antiviral Agents; Plant Viruses; Virus Replication | 1988 |
Significance of the differential growth, relative tissue shifts and the vascular bed in limb development.
Topics: Abnormalities, Drug-Induced; Adenine; Animals; Chick Embryo; Citrates; Citric Acid; Dactinomycin; Ectoderm; Extremities; Mesoderm; Morphogenesis; Teratogens; Wings, Animal | 1988 |
SVLM21, a mutant of Sindbis virus able to grow in Aedes albopictus cells in the absence of methionine, shows increased sensitivity to S-adenosylhomocysteine hydrolase inhibitors such as neplanocin A.
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Aedes; Animals; Antiviral Agents; Cell Line; Genes, Viral; Hydrolases; Methionine; Methyltransferases; Mutation; S-Adenosylmethionine; Sindbis Virus; Tubercidin; Viral Plaque Assay | 1988 |
Antiviral effects of dihydroxypropyladenine [RS)-DHPA) and bromovinyldeoxyuridine (BVDU) on plant viruses.
Topics: Adenine; Antiviral Agents; Bromodeoxyuridine; Mosaic Viruses; Plant Viruses; Plants | 1987 |
Comparative efficacy of broad-spectrum antiviral agents as inhibitors of African swine fever virus replication in vitro.
Topics: Adenine; African Swine Fever Virus; Amides; Animals; Antiviral Agents; Dose-Response Relationship, Drug; Iridoviridae; Organophosphonates; Organophosphorus Compounds; Pyrazoles; Ribavirin; Ribonucleosides; Ribose; Thymidine; Tubercidin; Vero Cells; Virus Replication; Zidovudine | 1987 |
Effect of 9-(S)-(2,3-dihydroxypropyl)adenine on experimental rabies infection in laboratory mice.
Topics: Adenine; Administration, Oral; Animals; Mice; Rabies; Rabies virus | 1980 |
Characteristics of the antiviral effect of 9-(S)-(2, 3-dihydroxypropyl)adenine.
Topics: Adenine; Animals; Cell Line; Chick Embryo; Rabbits; RNA, Messenger; RNA, Viral; Vaccinia virus; Virus Replication | 1980 |
Studies on the effect of 9-(R, S)-(2,3-dihydroxypropyl)adenine on tick-borne encephalitis virus.
Topics: Adenine; Animals; Antiviral Agents; Encephalitis Viruses, Tick-Borne; Encephalitis, Tick-Borne; Hemagglutination, Viral; Mice | 1982 |
Transport of antiviral agent 9-(S)-(2,3-dihydroxypropyl) adenine to animal cells.
Topics: Adenine; Animals; Antiviral Agents; Biological Transport, Active; Cell Line; Cells; Chick Embryo; Eukaryotic Cells; HeLa Cells; Humans; Kinetics; Lung; Nucleosides; Rabbits; Temperature; Vaccinia virus | 1983 |
Metabolism of the broad-spectrum antiviral agent, 9-(S)-(2,3-dihydroxypropyl) adenine, in different cell lines.
Topics: Adenine; Animals; Antiviral Agents; Cats; Cell Line; Chlorocebus aethiops; HeLa Cells; Humans; Rabbits; Vesicular stomatitis Indiana virus | 1983 |
Virus inhibitory effect of combination of 9-(S)-(2,3-dihydroxypropyl) adenine and 6-azauridine.
Topics: Adenine; Antiviral Agents; Azauridine; Drug Synergism; HeLa Cells; Humans; Vaccinia virus | 1980 |
Inhibition of bluetongue and Colorado tick fever orbiviruses by selected antiviral substances.
Topics: 3-Deazauridine; Adenine; Antiviral Agents; Bluetongue virus; Cells, Cultured; Colorado tick fever virus; Guanosine; Reoviridae; Ribavirin | 1981 |
Inhibition of rotaviruses by selected antiviral substances: mechanisms of viral inhibition and in vivo activity.
Topics: Adenine; Animals; Antiviral Agents; Guanine; Mice; Mice, Inbred Strains; Peptide Biosynthesis; Reoviridae; Reoviridae Infections; Ribavirin; RNA, Viral; Rotavirus | 1982 |
[X-ray study of an antiviral agent (S)-9-(2,3-dihydroxypropyl)adenine].
Topics: Adenine; Antiviral Agents; Crystallization; Hydrogen Bonding; Molecular Conformation; X-Ray Diffraction | 1984 |
Quantum chemical calculation of the (S)-9-(2,3-dihydroxypropyl)adenine molecule.
Topics: Adenine; Antiviral Agents; Molecular Conformation; Quantum Theory; Ribose; Thermodynamics; Xylose | 1980 |
Metabolism of 9-(S)-(2,3-dihydroxypropyl)adenine, an antiviral agent, in mice.
Topics: Adenine; Animals; Antiviral Agents; Female; Mice; Xanthine Oxidase | 1981 |
Inhibitory effect of a broad-spectrum antiviral agent, (S)-9-(2,3-dihydroxypropyl)adenine, on spermatogenesis in mice.
Topics: Adenine; Aging; Animals; Antiviral Agents; Blood Cell Count; Depression, Chemical; Male; Mice; Reproduction; Spermatogenesis; Spermatozoa; Testis | 1981 |
Embryotoxicity of 9-(S)-(2,3-dihydroxypropyl)adenine.
Topics: Adenine; Animals; Chick Embryo; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Isomerism; Mice; Morphogenesis; Structure-Activity Relationship | 1981 |
Sequence-specific hypomethylation of the tobacco genome induced with dihydroxypropyladenine, ethionine and 5-azacytidine.
Topics: Adenine; Adenosylhomocysteinase; Azacitidine; Cells, Cultured; Deoxyribonucleases, Type II Site-Specific; DNA-Cytosine Methylases; DNA, Plant; Ethionine; Genome, Plant; Hydrolases; Methylation; Nicotiana; Plants, Toxic | 1994 |
High recombinagenic activities of three antiviral agents, adenine derivatives, in the Drosophila wing spot test.
Topics: Abnormalities, Drug-Induced; Adenine; Animals; Antiviral Agents; Dose-Response Relationship, Drug; Drosophila melanogaster; Female; Larva; Male; Mitosis; Mutagenicity Tests; Mutagens; Organophosphonates; Recombination, Genetic; Wings, Animal | 1994 |
Transaldimination induces coenzyme reorientation in pig kidney dopa decarboxylase.
Topics: 5-Hydroxytryptophan; Adenine; Amines; Animals; Circular Dichroism; Dopa Decarboxylase; Hydroxyindoleacetic Acid; Kidney; Levodopa; Ligands; Pyridoxal Phosphate; Schiff Bases; Substrate Specificity; Swine | 1995 |
Evaluation of the impact of S-adenosylhomocysteine metabolic pools on cytosine methylation of the tobacco genome.
Topics: Adenine; Cell Line; DNA Methylation; DNA, Plant; DNA, Ribosomal; Genome, Plant; Nicotiana; Plants, Toxic; RNA, Ribosomal, 5S; S-Adenosylhomocysteine; S-Adenosylmethionine | 1998 |
Synthesis of DHPA analogs and their inhibitory activities of human recombinant S-adenosyl-L-homocysteine hydrolase.
Topics: Adenine; Adenosylhomocysteinase; Antiviral Agents; Carcinoma, Hepatocellular; Drug Design; Enzyme Inhibitors; Humans; Hydrolases; Kinetics; Liver Neoplasms; Recombinant Proteins; Tumor Cells, Cultured | 1997 |
Mapping of 5-methylcytosine residues in Nicotiana tabacum 5S rRNA genes by genomic sequencing.
Topics: 5-Methylcytosine; Adenine; Base Sequence; Consensus Sequence; Cytosine; DNA Methylation; DNA, Plant; Genes, Plant; Molecular Sequence Data; Nicotiana; Plants, Toxic; Polymerase Chain Reaction; RNA, Ribosomal, 5S; Sequence Analysis, DNA | 1998 |
Drug-induced hypomethylation of a posttranscriptionally silenced transgene locus of tobacco leads to partial release of silencing.
Topics: 3' Untranslated Regions; Adenine; Azacitidine; Cells, Cultured; Cytosine; DNA Methylation; DNA, Bacterial; Gene Expression Regulation, Plant; Gene Silencing; Genes, Reporter; Kanamycin Kinase; Nicotiana; Open Reading Frames; Plants, Genetically Modified; Plants, Toxic; Transcription, Genetic; Transgenes | 2000 |
Comparative analysis of DNA methylation in tobacco heterochromatic sequences.
Topics: Adenine; Blotting, Southern; Cells, Cultured; Cytosine; DNA Methylation; DNA Restriction Enzymes; DNA, Plant; DNA, Satellite; Genome, Plant; Heterochromatin; Interphase; Nicotiana; Nucleotides; Plants, Toxic; Repetitive Sequences, Nucleic Acid; Transcription, Genetic | 2000 |
[Synthesis of S-9-(2,3-dihydroxypropyl)adenine (DHPA) analogs and their inhibition of S-adenosyl-L-homocysteine (SAH) hydrolase].
Topics: Adenine; Adenosylhomocysteinase; Animals; Antiviral Agents; Hydrolases; Molecular Structure; Rats | 1997 |
[Inhibitory effect of the combination of DHPAs and hyperbaric oxygen on Japanese B encephalitis virus infection in mice].
Topics: Adenine; Animals; Antiviral Agents; Encephalitis Virus, Japanese; Encephalitis, Japanese; Hyperbaric Oxygenation; Mice; Random Allocation | 2001 |
Screening for microtubule-disrupting antifungal agents by using a mitotic-arrest mutant of Aspergillus nidulans and novel action of phenylalanine derivatives accompanying tubulin loss.
Topics: Adenine; Antifungal Agents; Antineoplastic Agents; Aspergillus nidulans; Blotting, Western; Cell Nucleus; Chromosomes, Fungal; Coloring Agents; Drug Evaluation, Preclinical; Electrophoresis, Polyacrylamide Gel; Fungal Proteins; Fungi; Microbial Sensitivity Tests; Microscopy, Fluorescence; Microtubules; Mitosis; Mitotic Index; Nocodazole; Oxazines; Phenylalanine; Tubulin; Xanthenes | 2004 |
Characterization of S-adenosylhomocysteine hydrolase from Cryptosporidium parvum.
Topics: Adenine; Adenosylhomocysteinase; Amino Acid Sequence; Animals; Cryptosporidium parvum; Escherichia coli; Gene Expression; Gene Expression Regulation, Developmental; Introns; Molecular Sequence Data; Molecular Weight; Recombinant Fusion Proteins; RNA, Messenger; RNA, Protozoan; Sequence Homology, Amino Acid; Vidarabine | 2007 |
Grapevine vitivirus A eradication in Vitis vinifera explants by antiviral drugs and thermotherapy.
Topics: Adenine; Antiviral Agents; Flexiviridae; Hot Temperature; Plant Diseases; Ribavirin; Vitis | 2007 |
Efficacy of S-adenosylhomocysteine hydrolase inhibitors, D-eritadenine and (S)-DHPA, against the growth of Cryptosporidium parvum in vitro.
Topics: Adenine; Adenosylhomocysteinase; Cryptosporidium parvum; Dose-Response Relationship, Drug; Enzyme Inhibitors; Recombinant Proteins; Regression Analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Protozoan | 2010 |
Inhibition of SAH-hydrolase activity during seed germination leads to deregulation of flowering genes and altered flower morphology in tobacco.
Topics: Adenine; Adenosylhomocysteinase; Blotting, Southern; DNA Methylation; DNA Primers; DNA, Complementary; Epigenesis, Genetic; Flowers; Gene Expression Regulation, Plant; Germination; Nicotiana; Plant Proteins; Pollen; Statistics, Nonparametric | 2011 |
Hypomethylating drugs efficiently decrease cytosine methylation in telomeric DNA and activate telomerase without affecting telomere lengths in tobacco cells.
Topics: Adenine; Cells, Cultured; Cytidine; DNA Methylation; DNA, Plant; Enzyme Activation; Epigenesis, Genetic; Nicotiana; Nucleosomes; Plant Proteins; Telomerase; Telomere; Transcription, Genetic | 2011 |
3-(3,4-Dihydroxyphenyl)adenine, a urinary DNA adduct formed in mice exposed to high concentrations of benzene.
Topics: Adenine; Administration, Inhalation; Animals; Benzene; Biomarkers; Carcinogens; Chromatography, High Pressure Liquid; DNA Adducts; Male; Mass Spectrometry; Mice; Reference Standards; Spectrometry, Mass, Electrospray Ionization | 2013 |
Lipases as tools in the synthesis of prodrugs from racemic 9-(2,3-dihydroxypropyl)adenine.
Topics: Adenine; Chitosan; Enzymes, Immobilized; Esterification; Esters; Geotrichum; Lipase; Prodrugs | 2012 |
Supramolecular polymerization of a prebiotic nucleoside provides insights into the creation of sequence-controlled polymers.
Topics: Adenine; Gold; Nanostructures; Polymerization; Polymers; Prebiotics | 2016 |
Regioselective Palmitoylation of 9-(2,3-Dihydroxy- propyl)adenine Catalyzed by a Glycopolymer-enzyme Conjugate.
Topics: Adenine; Candida; Catalysis; Enzymes, Immobilized; Fungal Proteins; Glycosylation; Hexanes; Lipase; Lipoylation; Polymers; Solvents; Stereoisomerism | 2016 |
Novel mitochondrial targeting charge-reversal polysaccharide hybrid shell/core nanoparticles for prolonged systemic circulation and antitumor drug delivery.
Topics: Adenine; Animals; Antineoplastic Agents; Berberine; Cell Line; Chitosan; Curcumin; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Drug Liberation; Endocytosis; Humans; Hyaluronan Receptors; Hyaluronic Acid; Mice; Mice, Nude; Micelles; Mitochondria; Nanoparticles; Polymers; Polysaccharides | 2019 |