adenine and 8-hydroxyguanine

adenine has been researched along with 8-hydroxyguanine in 76 studies

Research

Studies (76)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (1.32)	18.7374
1990's	22 (28.95)	18.2507
2000's	34 (44.74)	29.6817
2010's	15 (19.74)	24.3611
2020's	4 (5.26)	2.80

Authors

Authors	Studies
Ciompi, ML; Lucacchini, A; Mazzoni, MR; Segnini, D	1
Essigmann, JM; Esteve, A; Kuziemko, GM; Morningstar, ML; Wood, ML	1
Haimanot, R; Malins, DC	1
Leukel, P; Mayer, KK; Müller, K; Wiegrebe, W	1
Ho, YS; Lin, JK; Lo, MJ; Wang, YJ	1
Becker, D; Sevilla, M; Swarts, SG; Wheeler, KT	1
Garner, MM; Gunselman, SJ; Malins, DC; Polissar, NL	1
Cillo, J; Clarke, ND; Gogos, A; Lu, AL	1
Elder, RH; Hang, B; Margison, GP; Singer, B	1
Aruoma, OI; England, TG; Halliwell, B; Jenner, A	2
Burrows, CJ; Duarte, V; Hickerson, RP; Muller, JG	1
Dix, TA; Simandan, T; Sun, J	1
Gabbita, SP; Lovell, MA; Markesbery, WR	1
Arvai, AS; Guan, Y; Lloyd, S; Manuel, RC; Miller, JH; Mol, CD; Parikh, SS; Tainer, JA	1
Dizdaroglu, M	1
Dogliotti, E; Fortini, P; Laval, J; Parlanti, E; Sidorkina, OM	1
Clarke, ND; Gogos, A; Granek, JA; Noll, DM	1
Foksinski, M; Jaruga, P; Makarewicz, R; Olinski, R	1
Dizdaroglu, M; Sentürker, S	1
Halota, W; Jaruga, B; Jaruga, P; Olczak, A; Olinski, R	1
Kolodner, RD; Marsischky, GT; Ni, TT	1
Fujiwara, T; Imaiso, Y; Iwai, S; Nakabeppu, Y; Nishioka, K; Oda, H; Ohtsubo, T; Shimokawa, H	1
Osheroff, N; Sabourin, M	1
Fukuoka, M; Inoue, H; Ohtsuka, E; Terashima, Y	1
Bohr, VA; Ganunis, R; Machwe, A; Orren, DK	1
Lu, AL	1
Kozai, S; Maruyama, T; Sasaki, F	1
Malins, DC; Ostrander, GK; Polissar, NL; Vinson, MA	1
Kim, SR; Nohmi, T; Saitoh, T; Shinmura, K; Takeuchi-Sasaki, M; Yamaguchi, S; Yokota, J	1
Bohr, VA; Cooper, MP; Karmakar, P; Machwe, A; Orren, DK; Piotrowski, J	1
Bassett, H; Boldogh, I; Lee, MS; Lloyd, RS; McCullough, AK; Milligan, D	1
Barker, EA; Johnson, PM; Malins, DC; Polissar, NL; Vinson, MA; Wheeler, TM	1
Bohr, VA; Dianov, GL; Nyaga, SG; Souza-Pinto, N; Stevnsner, T; Thybo, T	1
Gorenstein, DG; House, PG; Lloyd, RS; Luxon, BA; Manuel, RC; Thiviyanathan, V; Volk, DE	1
Hayashi, H; Hirano, S; Matsumoto, Y; McKenna, AE; Nakabeppu, Y; Tominaga, Y	1
Bruskov, VI; Chernikov, AV; Malakhova, LV; Masalimov, ZK	1
Funk, MC; Hunt, CR; Parsian, AJ; Tao, TY	1
Bohr, VA; Dizdaroglu, M; Jaruga, P; Rodriguez, H; Tuo, J	2
Allgayer, H; Kolb, M; Kruis, W; Stuber, V	1
Dogliotti, E; Fortini, P; Laval, J; Macpherson, P; Parlanti, E	1
Drummond, JT; Iams, K; Larson, ED	1
Behmanesh, M; Hirano, S; Ichinoe, A; Nakabeppu, Y; Sakai, Y; Sakumi, K; Tominaga, Y; Tsuchimoto, D; Ushijima, Y; Wake, N	1
Dizdaroglu, M; Jaruga, P; O'Connor, T; Reddy, P; Rodriguez, H	1
Lindahl, T	1
Banerjee, A; Fromme, JC; Huang, SJ; Verdine, GL	1
Dizdaroglu, M; Evans, MK; Jaruga, P; Lohani, A; Nyaga, SG; Trzeciak, AR	1
Hogue, BA; Kim, D; McNeill, DR; Wilson, DM; Wong, HK	1
Back, JH; Chung, JH; Han, YS; Kim, DS; Park, JH	1
Akatsuka, S; Aung, TT; Dutta, KK; Jiang, L; Kasai, H; Kawai, Y; Lee, WH; Liu, YT; Naito, Y; Nakabeppu, Y; Ochi, H; Onuki, J; Sakumi, K; Shirase, T; Tominaga, Y; Toyokuni, S; Tsuruyama, T; Uchida, K; Yamada, Y; Yamasaki, A; Yamasaki, K; Yoshikawa, T	1
Handa, H; Hayashida, M; Ikegami, T; Ito, S; Kuraoka, I; Kwei, JS; Nakabeppu, Y; Suzuki, K; Tanaka, K	1
David, SS; Kim, T; Kool, ET; Livingston, AL; O'Shea, VL	1
Basu, AK; Burke, TJ; McGregor, WG; Mukhopadhyay, S; Tolentino, JH	1
Hayter, S; Lamers, R; Matheson, CD	1
Hitomi, K; Perry, JJ; Tainer, JA	1
Cramer, P; Damsma, GE	1
Harashima, H; Kamiya, H; Suzuki, T	1
Fletcher, HM; Reid, K; Robles, AG; Roy, F	1
Beckett, TL; Bradley, MA; Dowling, AL; LeVine, H; Lovell, MA; Matveev, SV; Murphy, MP; Niedowicz, DM; Weidner, AM	1
Kumar, A; Sevilla, MD	1
Chauleau, M; Shuman, S	1
Czubaty, A; Dudzińska, DA; Masłowska, K; Nałęcz, M; Saparbaev, M; Staroń, K; Tudek, B; Winczura, A; Winczura, K	1
Beard, WA; Freudenthal, BD; Kim, T; Perera, L; Schlick, T; Shock, DD; Wilson, SH	1
Chao, MR; Hsu, YW; Hu, CW; Lin, JH; Liu, HH	1
Al Balushi, K; Al-Husseini, I; Ali, BH; Mandel, P; Nemmar, A; Ribeiro, DA; Schupp, N	1
Cao, S; Chu, A; David, SS; Horvath, MP; O'Shea, VL; Richards, JL; Woods, RD	1
Bielen, A; Ciesla, JM; Janowska, B; Jaworek, J; Kot, M; Kowalczyk, P; Sados, B; Sokolowska, B; Szparecki, G; Tudek, B	1
David, SS; Doyle, EL; Hamm, ML; Majumdar, C; Manlove, AH; McKibbin, PL	1
Alenko, A; Burrows, CJ; Fleming, AM	1
Hall, AR; Harvey, S; Hollis, T; Kohli, RM; Parsonage, D; Perrino, FW; Swain, BE; Taylor, EW; Wang, F; Zahid, OK	1
Averill, AM; Hilzinger, TS; Kathe, SD; Lee, AJ; Nelson, SR; Wallace, SS; Warshaw, DM	1
David, SS; Krajewski, AE; Lee, JK; Majumdar, C; Manlove, AH; McKibbin, PL	1
Jung, H; Lee, S	1
Chirifu, M; Hirayama, S; Ikemizu, S; Morioka, H; Nakabeppu, Y; Nakamura, T; Okabe, K; Yamagata, Y	1
David, SS; Jang, S; Khuu, C; Majumdar, C; Schaich, MA; Schnable, BL; Van Houten, B; Watkins, SC	1

Reviews

3 review(s) available for adenine and 8-hydroxyguanine

Article	Year
Facts about the artifacts in the measurement of oxidative DNA base damage by gas chromatography-mass spectrometry. Free radical research, 1998, Volume: 29, Issue:6 Topics: Adenine; Animals; Artifacts; Base Pairing; Cattle; Cytosine; DNA; DNA Damage; DNA Repair; Gas Chromatography-Mass Spectrometry; Guanine; Humans; Oxidation-Reduction; Oxidative Stress; Pentoxyl; Pyrimidines; Temperature; Thymus Gland	1998
Base excision repair in nuclear and mitochondrial DNA. Progress in nucleic acid research and molecular biology, 2001, Volume: 68 Topics: Adenine; Aging; Animals; Base Sequence; Cell Line; Cell Nucleus; Cell-Free System; DNA; DNA Damage; DNA Glycosylases; DNA Polymerase beta; DNA Repair; DNA-Formamidopyrimidine Glycosylase; DNA, Mitochondrial; Guanine; Hypoxanthine; Lymphocytes; Mammals; Mice; Mitochondria; Molecular Sequence Data; N-Glycosyl Hydrolases; Oxidants; Oxidation-Reduction; Oxidative Stress; Point Mutation; Proliferating Cell Nuclear Antigen; Rats; Thymine	2001
Potential double-flipping mechanism by E. coli MutY. Progress in nucleic acid research and molecular biology, 2001, Volume: 68 Topics: Adenine; Amino Acid Sequence; Bacterial Proteins; Base Pair Mismatch; Carbon-Oxygen Lyases; Catalysis; Catalytic Domain; Deoxyribonuclease IV (Phage T4-Induced); DNA Damage; DNA Glycosylases; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Guanine; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; N-Glycosyl Hydrolases; Phosphoric Monoester Hydrolases; Protein Conformation; Protein Structure, Tertiary; Pyrophosphatases; Sequence Alignment; Sequence Homology, Amino Acid; Structure-Activity Relationship; Substrate Specificity	2001

Trials

1 trial(s) available for adenine and 8-hydroxyguanine

Article	Year
Oxidative DNA base damage in lymphocytes of HIV-infected drug users. Free radical research, 1999, Volume: 31, Issue:3 Topics: Adenine; Adolescent; Adult; Chromatin; Cytosine; DNA Damage; Guanine; HIV Infections; Humans; Lymphocytes; Male; Oxidation-Reduction; Oxidative Stress; Substance Abuse, Intravenous; Uracil	1999

Other Studies

72 other study(ies) available for adenine and 8-hydroxyguanine

Article	Year
Urate-binding proteins in plasma studied by affinity chromatography. Advances in experimental medicine and biology, 1979, Volume: 122B Topics: Adenine; Carrier Proteins; Chromatography, Affinity; Guanine; Humans; Indicators and Reagents; Uric Acid; Xanthines	1979
Genetic effects of oxidative DNA damage: comparative mutagenesis of 7,8-dihydro-8-oxoguanine and 7,8-dihydro-8-oxoadenine in Escherichia coli. Nucleic acids research, 1992, Nov-25, Volume: 20, Issue:22 Topics: Adenine; Bacteriophage M13; Base Sequence; Chromatography, High Pressure Liquid; DNA Damage; DNA, Recombinant; Escherichia coli; Guanine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutagenicity Tests; Mutagens; Oligodeoxyribonucleotides; Oxidation-Reduction; Restriction Mapping; Transformation, Bacterial	1992
Major alterations in the nucleotide structure of DNA in cancer of the female breast. Cancer research, 1991, Oct-01, Volume: 51, Issue:19 Topics: Adenine; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cell Transformation, Neoplastic; Chromatography, Gas; DNA; Female; Guanine; Humans; Hydroxylation; Mass Spectrometry; Pyrimidines	1991
Modification of DNA bases by anthralin and related compounds. Biochemical pharmacology, 1995, May-26, Volume: 49, Issue:11 Topics: Adenine; Animals; Anthralin; Cattle; Dermatologic Agents; DNA; DNA Damage; Gas Chromatography-Mass Spectrometry; Guanine; Hydroxylation; Pyrimidines	1995
Oxidative modification of DNA bases in rat liver and lung during chemical carcinogenesis and aging. Chemico-biological interactions, 1995, Volume: 94, Issue:2 Topics: 2-Acetylaminofluorene; Adenine; Aging; Animals; Antineoplastic Agents; Disease Models, Animal; DNA Damage; DNA, Neoplasm; Gas Chromatography-Mass Spectrometry; Guanine; Hydrolysis; Liver; Liver Neoplasms, Experimental; Lung; Lung Neoplasms; Male; Methylamines; Nitrates; Oxidation-Reduction; Pyrimidines; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Thymine; Uracil	1995
Radiation-induced DNA damage as a function of hydration. II. Base damage from electron-loss centers. Radiation research, 1996, Volume: 145, Issue:3 Topics: Adenine; Animals; Base Composition; Cytosine; DNA; DNA Damage; Electron Spin Resonance Spectroscopy; Electrons; Gas Chromatography-Mass Spectrometry; Guanine; Hydrolysis; Nucleic Acid Conformation; Pyrimidines; Salmon; Thymine	1996
Mutagenic DNA base modifications are correlated with lesions in nonneoplastic hepatic tissue of the English sole carcinogenesis model. Cancer research, 1996, Dec-15, Volume: 56, Issue:24 Topics: Adenine; Age Factors; Animals; Confounding Factors, Epidemiologic; Fish Diseases; Guanine; Liver Diseases; Liver Neoplasms; Mutagenesis; Precancerous Conditions	1996
Specific recognition of A/G and A/7,8-dihydro-8-oxoguanine (8-oxoG) mismatches by Escherichia coli MutY: removal of the C-terminal domain preferentially affects A/8-oxoG recognition. Biochemistry, 1996, Dec-24, Volume: 35, Issue:51 Topics: Adenine; Amino Acid Sequence; Base Composition; Base Sequence; Binding Sites; DNA Damage; DNA Glycosylases; DNA Repair; Endopeptidases; Escherichia coli; Guanine; Molecular Sequence Data; N-Glycosyl Hydrolases; Oligodeoxyribonucleotides; Peptide Fragments; Sequence Homology, Amino Acid; Substrate Specificity	1996
Targeted deletion of alkylpurine-DNA-N-glycosylase in mice eliminates repair of 1,N6-ethenoadenine and hypoxanthine but not of 3,N4-ethenocytosine or 8-oxoguanine. Proceedings of the National Academy of Sciences of the United States of America, 1997, Nov-25, Volume: 94, Issue:24 Topics: Adenine; Animals; Cell-Free System; Cytosine; DNA Glycosylases; DNA Repair; Guanine; Hydrolysis; Hypoxanthine; Mice; Mice, Inbred BALB C; Mice, Knockout; N-Glycosyl Hydrolases; Recombinant Proteins; Substrate Specificity	1997
Measurement of oxidative DNA damage by gas chromatography-mass spectrometry: ethanethiol prevents artifactual generation of oxidized DNA bases. The Biochemical journal, 1998, Apr-15, Volume: 331 ( Pt 2) Topics: Adenine; Animals; Cattle; Cytosine; DNA; DNA Damage; Gas Chromatography-Mass Spectrometry; Guanine; Guanine Deaminase; Oxidation-Reduction; Pentoxyl; Sulfhydryl Compounds; Temperature	1998
Gel electrophoretic detection of 7,8-dihydro-8-oxoguanine and 7, 8-dihydro-8-oxoadenine via oxidation by Ir (IV). Nucleic acids research, 1998, May-01, Volume: 26, Issue:9 Topics: Adenine; DNA Damage; DNA Primers; Electrophoresis, Polyacrylamide Gel; Guanine; Iridium; Oxidation-Reduction	1998
Oxidation of DNA bases, deoxyribonucleosides and homopolymers by peroxyl radicals. The Biochemical journal, 1998, Oct-15, Volume: 335 ( Pt 2) Topics: Adenine; Amidines; Base Pairing; Cytosine; Deoxyribonucleosides; DNA; Free Radicals; Guanine; Mass Spectrometry; Oxidation-Reduction; Purines; Pyrimidines; Reactive Oxygen Species; Thymine	1998
Increased nuclear DNA oxidation in the brain in Alzheimer's disease. Journal of neurochemistry, 1998, Volume: 71, Issue:5 Topics: Adenine; Aged; Aged, 80 and over; Alzheimer Disease; Brain; Cadaver; Cell Nucleus; Cytosine; DNA; Gas Chromatography-Mass Spectrometry; Guanine; Humans; Oxidation-Reduction; Pyrimidines; Reference Values; Tissue Distribution	1998
MutY catalytic core, mutant and bound adenine structures define specificity for DNA repair enzyme superfamily. Nature structural biology, 1998, Volume: 5, Issue:12 Topics: Adenine; Amino Acid Sequence; Base Pair Mismatch; Catalytic Domain; Crystallography, X-Ray; DNA; DNA Glycosylases; DNA Repair; Guanine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; N-Glycosyl Hydrolases; Protein Conformation; Substrate Specificity	1998
Determination of oxidative DNA base damage by gas chromatography-mass spectrometry. Effect of derivatization conditions on artifactual formation of certain base oxidation products. Free radical research, 1998, Volume: 29, Issue:4 Topics: Adenine; Animals; Artifacts; Cytosine; DNA; DNA Damage; Gas Chromatography-Mass Spectrometry; Guanine; Hydantoins; Hydrolysis; Nitrogen; Oxidation-Reduction; Pentoxyl; Purines; Pyrimidines; Temperature; Time Factors	1998
The type of DNA glycosylase determines the base excision repair pathway in mammalian cells. The Journal of biological chemistry, 1999, May-21, Volume: 274, Issue:21 Topics: Adenine; Animals; Base Sequence; Cells, Cultured; DNA Glycosylases; DNA Repair; Guanine; HeLa Cells; Humans; Hypoxanthine; Mice; N-Glycosyl Hydrolases	1999
The C-terminal domain of the adenine-DNA glycosylase MutY confers specificity for 8-oxoguanine.adenine mispairs and may have evolved from MutT, an 8-oxo-dGTPase. Biochemistry, 1999, May-18, Volume: 38, Issue:20 Topics: Adenine; Amino Acid Sequence; Base Pair Mismatch; DNA Glycosylases; DNA Repair; DNA, Bacterial; Escherichia coli; Guanine; Humans; Kinetics; Molecular Sequence Data; N-Glycosyl Hydrolases; Peptide Fragments; Protein Structure, Tertiary; Sequence Analysis; Sequence Homology, Amino Acid	1999
Oxidative DNA base damage in cancerous tissues of patients undergoing brachytherapy. Cancer letters, 1998, Oct-23, Volume: 132, Issue:1-2 Topics: Adenine; Brachytherapy; Cytosine; DNA Damage; DNA, Neoplasm; Female; Gas Chromatography-Mass Spectrometry; Guanine; Humans; Oxidation-Reduction; Pyrimidines; Uracil; Uterine Cervical Neoplasms	1998
The effect of experimental conditions on the levels of oxidatively modified bases in DNA as measured by gas chromatography-mass spectrometry: how many modified bases are involved? Prepurification or not? Free radical biology & medicine, 1999, Volume: 27, Issue:3-4 Topics: Adenine; Animals; Artifacts; Cattle; Cytosine; DNA; Gas Chromatography-Mass Spectrometry; Guanine; Hydrolysis; Nucleotides; Oxidation-Reduction; Pentoxyl; Trifluoroacetic Acid; Uracil	1999
MSH2 and MSH6 are required for removal of adenine misincorporated opposite 8-oxo-guanine in S. cerevisiae. Molecular cell, 1999, Volume: 4, Issue:3 Topics: Adenine; Base Pair Mismatch; DNA Damage; DNA Repair; DNA-Binding Proteins; Fungal Proteins; Guanine; Models, Genetic; Mutagenesis; MutS Homolog 2 Protein; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins	1999
Identification of human MutY homolog (hMYH) as a repair enzyme for 2-hydroxyadenine in DNA and detection of multiple forms of hMYH located in nuclei and mitochondria. Nucleic acids research, 2000, Mar-15, Volume: 28, Issue:6 Topics: Adenine; Amino Acid Sequence; Blotting, Western; Cell Extracts; Cell Nucleus; DNA; DNA Glycosylases; DNA Repair; Gene Expression Profiling; Guanine; HeLa Cells; Humans; Isoenzymes; Jurkat Cells; Mitochondria; Molecular Sequence Data; Molecular Weight; N-Glycosyl Hydrolases; Peptides; Recombinant Proteins; RNA, Messenger; Sequence Alignment; Substrate Specificity	2000
Sensitivity of human type II topoisomerases to DNA damage: stimulation of enzyme-mediated DNA cleavage by abasic, oxidized and alkylated lesions. Nucleic acids research, 2000, May-01, Volume: 28, Issue:9 Topics: Adenine; Alkylation; Apurinic Acid; Base Sequence; DNA; DNA Adducts; DNA Damage; DNA Repair; DNA Topoisomerases, Type II; DNA-Binding Proteins; Guanine; Humans; Isoenzymes; Mutation; Oligonucleotides; Oxidation-Reduction; Plasmids; Sensitivity and Specificity	2000
Further studies of KMnO4 oxidation of synthetic DNAs containing oxidatively damaged bases. Nucleic acids symposium series, 1999, Issue:42 Topics: Adenine; Base Sequence; DNA; DNA Damage; Guanine; Oligodeoxyribonucleotides; Oxidation-Reduction; Potassium Permanganate; Uracil	1999
Selective blockage of the 3'-->5' exonuclease activity of WRN protein by certain oxidative modifications and bulky lesions in DNA. Nucleic acids research, 2000, Jul-15, Volume: 28, Issue:14 Topics: Adenine; Base Sequence; DNA; DNA Adducts; DNA Helicases; DNA Polymerase I; Exodeoxyribonucleases; Exonucleases; Guanine; Hypoxanthine; Mutation; Oxidation-Reduction; RecQ Helicases; Substrate Specificity; Uracil; Werner Syndrome Helicase	2000
Repair of A/G and A/8-oxoG mismatches by MutY adenine DNA glycosylase. Methods in molecular biology (Clifton, N.J.), 2000, Volume: 152 Topics: Adenine; Base Pair Mismatch; Binding Sites; DNA Glycosylases; DNA Primers; DNA Repair; Escherichia coli; Guanine; Kinetics; Mutation; N-Glycosyl Hydrolases; Polymerase Chain Reaction	2000
Method for the synthesis of uric acid derivatives. Nucleosides, nucleotides & nucleic acids, 2000, Volume: 19, Issue:7 Topics: 1-Propanol; Adenine; Alkylation; Ammonia; Guanine; Hydrocarbons, Iodinated; Mass Spectrometry; Methylation; Purines; Uric Acid	2000
Single 8-oxo-guanine and 8-oxo-adenine lesions induce marked changes in the backbone structure of a 25-base DNA strand. Proceedings of the National Academy of Sciences of the United States of America, 2000, Nov-07, Volume: 97, Issue:23 Topics: Adenine; DNA; DNA Damage; Guanine; Hydroxyl Radical; Multivariate Analysis; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Spectroscopy, Fourier Transform Infrared	2000
Adenine excisional repair function of MYH protein on the adenine:8-hydroxyguanine base pair in double-stranded DNA. Nucleic acids research, 2000, Dec-15, Volume: 28, Issue:24 Topics: Adenine; Animals; Base Pair Mismatch; Base Sequence; Carbon-Oxygen Lyases; Deoxyribonuclease IV (Phage T4-Induced); DNA; DNA Glycosylases; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA-Formamidopyrimidine Glycosylase; Escherichia coli; Escherichia coli Proteins; Genes, Bacterial; Genetic Complementation Test; Guanine; Humans; Kinetics; Mitochondria; Mutation; N-Glycosyl Hydrolases; Nuclear Proteins; Oligodeoxyribonucleotides; Polymorphism, Single Nucleotide; Potassium Chloride; Protein Binding; Protein Isoforms; Recombinant Fusion Proteins; Schizosaccharomyces; Sodium Chloride; Spodoptera	2000
A functional interaction of Ku with Werner exonuclease facilitates digestion of damaged DNA. Nucleic acids research, 2001, May-01, Volume: 29, Issue:9 Topics: Adenine; Antigens, Nuclear; Cell Line; Cell Nucleus; DNA; DNA Damage; DNA Helicases; DNA-Binding Proteins; Exodeoxyribonucleases; Exonucleases; Guanine; HeLa Cells; Humans; Ku Autoantigen; Nuclear Proteins; RecQ Helicases; Replication Protein A; Werner Syndrome Helicase	2001
hMYH cell cycle-dependent expression, subcellular localization and association with replication foci: evidence suggesting replication-coupled repair of adenine:8-oxoguanine mispairs. Nucleic acids research, 2001, Jul-01, Volume: 29, Issue:13 Topics: Adenine; Base Pair Mismatch; Blotting, Western; Cell Cycle; Cell Division; Cell Line; Cell Nucleus; Cytoplasm; DNA Glycosylases; DNA Repair; DNA Repair Enzymes; DNA Replication; DNA-Formamidopyrimidine Glycosylase; Fluorescent Antibody Technique, Indirect; G1 Phase; Guanine; Humans; Mitochondria; N-Glycosyl Hydrolases; Phosphoric Monoester Hydrolases; Proliferating Cell Nuclear Antigen; Protein Transport; S Phase; Tumor Cells, Cultured	2001
Age-related radical-induced DNA damage is linked to prostate cancer. Cancer research, 2001, Aug-15, Volume: 61, Issue:16 Topics: Adenine; Age Factors; Cell Transformation, Neoplastic; DNA; DNA Damage; DNA, Neoplasm; Gas Chromatography-Mass Spectrometry; Guanine; Humans; Hydroxyl Radical; Logistic Models; Male; Middle Aged; Models, Biological; Prostate; Prostatic Neoplasms; Pyrimidines	2001
Replication-associated repair of adenine:8-oxoguanine mispairs by MYH. Current biology : CB, 2002, Feb-19, Volume: 12, Issue:4 Topics: Adenine; Animals; Base Pair Mismatch; Cell Line; DNA Glycosylases; DNA Repair; DNA Replication; Guanine; Mice; Models, Biological; Mutation; N-Glycosyl Hydrolases; Proliferating Cell Nuclear Antigen	2002
Heat-induced formation of reactive oxygen species and 8-oxoguanine, a biomarker of damage to DNA. Nucleic acids research, 2002, Mar-15, Volume: 30, Issue:6 Topics: Adenine; Biomarkers; DNA; DNA Damage; Guanine; Hot Temperature; Hydrogen Peroxide; Kinetics; Oxidative Stress; Reactive Oxygen Species	2002
The effect of DNA damage on the formation of protein/DNA complexes. Mutation research, 2002, Apr-25, Volume: 501, Issue:1-2 Topics: Adenine; Binding Sites; DNA; DNA Damage; DNA-Binding Proteins; Guanine; Promoter Regions, Genetic; Protein Binding; Transcription Factor AP-1	2002
The cockayne syndrome group B gene product is involved in cellular repair of 8-hydroxyadenine in DNA. The Journal of biological chemistry, 2002, Aug-23, Volume: 277, Issue:34 Topics: Adenine; DNA Helicases; DNA Repair; DNA Repair Enzymes; Gamma Rays; Guanine; Humans; Poly-ADP-Ribose Binding Proteins	2002
Effects of bile acids on base hydroxylation in a model of human colonic mucosal DNA. Cancer detection and prevention, 2002, Volume: 26, Issue:1 Topics: Adenine; Animals; Cattle; Chenodeoxycholic Acid; Colon; Colonic Neoplasms; Deoxycholic Acid; DNA; DNA Damage; Gas Chromatography-Mass Spectrometry; Gastrointestinal Agents; Guanine; Humans; Hydroxylation; Intestinal Mucosa; Models, Chemical; Reactive Oxygen Species; Salicylates; Thymus Gland	2002
Base excision repair of adenine/8-oxoguanine mispairs by an aphidicolin-sensitive DNA polymerase in human cell extracts. Oncogene, 2002, Aug-08, Volume: 21, Issue:34 Topics: Adenine; Aphidicolin; Base Pair Mismatch; Base Pairing; Cell Extracts; DNA; DNA Primers; DNA Repair; Drug Resistance; Enzyme Inhibitors; Guanine; HeLa Cells; Humans; Nucleic Acid Synthesis Inhibitors	2002
Primary fibroblasts of Cockayne syndrome patients are defective in cellular repair of 8-hydroxyguanine and 8-hydroxyadenine resulting from oxidative stress. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2003, Volume: 17, Issue:6 Topics: Adenine; Adult; Cell Line; Child; Child, Preschool; Cockayne Syndrome; DNA; DNA Damage; DNA Repair; Endonucleases; Exonucleases; Female; Guanine; Humans; Infant; Male; Oxidative Stress	2003
Strand-specific processing of 8-oxoguanine by the human mismatch repair pathway: inefficient removal of 8-oxoguanine paired with adenine or cytosine. DNA repair, 2003, Nov-21, Volume: 2, Issue:11 Topics: Adenine; Base Pair Mismatch; Base Sequence; Cell Line, Tumor; Cytosine; DNA Damage; DNA Repair; Guanine; HeLa Cells; Humans; Models, Genetic	2003
Identification and characterization of two forms of mouse MUTYH proteins encoded by alternatively spliced transcripts. Nucleic acids research, 2004, Volume: 32, Issue:2 Topics: Adenine; Alternative Splicing; Amino Acid Sequence; Animals; Cell Line; Cell Nucleus; DNA Glycosylases; DNA-(Apurinic or Apyrimidinic Site) Lyase; Gene Deletion; Guanine; Isoenzymes; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Molecular Sequence Data; Protein Transport; Recombinant Fusion Proteins; RNA, Messenger; Solubility; Stem Cells; Thymus Gland	2004
Overexpression and rapid purification of Escherichia coli formamidopyrimidine-DNA glycosylase. Protein expression and purification, 2004, Volume: 34, Issue:1 Topics: Adenine; Carboxymethylcellulose Sodium; Chromatography, DEAE-Cellulose; Cloning, Molecular; DNA Damage; DNA Repair; DNA-Formamidopyrimidine Glycosylase; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gas Chromatography-Mass Spectrometry; Gene Expression Regulation, Bacterial; Genetic Vectors; Guanine; Kinetics; Nitrous Oxide; Pyrimidines; Recombinant Proteins; Substrate Specificity; Temperature	2004
Molecular biology: ensuring error-free DNA repair. Nature, 2004, Feb-12, Volume: 427, Issue:6975 Topics: Adenine; Binding Sites; Crystallography, X-Ray; DNA; DNA Damage; DNA Glycosylases; Geobacillus stearothermophilus; Guanine; N-Glycosyl Hydrolases; Protein Conformation; Structure-Activity Relationship	2004
Structural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylase. Nature, 2004, Feb-12, Volume: 427, Issue:6975 Topics: Adenine; Base Pairing; Binding Sites; Catalysis; Cross-Linking Reagents; Crystallography, X-Ray; Disulfides; DNA; DNA Glycosylases; Geobacillus stearothermophilus; Guanine; Models, Molecular; N-Glycosyl Hydrolases; Protein Conformation; Structure-Activity Relationship	2004
Cellular repair of oxidatively induced DNA base lesions is defective in prostate cancer cell lines, PC-3 and DU-145. Carcinogenesis, 2004, Volume: 25, Issue:8 Topics: Adenine; Antioxidants; Blotting, Western; Catalase; Cell Division; Cell Line, Tumor; Cell Nucleus; Comet Assay; Cytosine; DNA; DNA Damage; Dose-Response Relationship, Drug; Electron Transport Complex IV; Gas Chromatography-Mass Spectrometry; Glutathione Peroxidase; Guanine; Humans; Kinetics; Male; Mitochondria; Oxygen; Polymorphism, Genetic; Prostatic Neoplasms; Superoxide Dismutase; Time Factors	2004
DNA damage levels and biochemical repair capacities associated with XRCC1 deficiency. Biochemistry, 2005, Nov-01, Volume: 44, Issue:43 Topics: Adenine; Animals; Binding Sites; Cell Extracts; Cell Line; Cricetinae; Cytosine; DNA Damage; DNA Repair; DNA-Binding Proteins; Female; Guanine; Mutation; Ovary; Time Factors; Uracil; X-ray Repair Cross Complementing Protein 1	2005
A distinct TthMutY bifunctional glycosylase that hydrolyzes not only adenine but also thymine opposite 8-oxoguanine in the hyperthermophilic bacterium, Thermus thermophilus. DNA repair, 2006, Aug-13, Volume: 5, Issue:8 Topics: Adenine; Amino Acid Sequence; Base Pair Mismatch; Base Sequence; Binding Sites; DNA Glycosylases; DNA Primers; DNA Repair; Guanine; Molecular Sequence Data; Sequence Analysis, DNA; Sequence Homology; Thermus thermophilus; Thymine	2006
Contrasting genome-wide distribution of 8-hydroxyguanine and acrolein-modified adenine during oxidative stress-induced renal carcinogenesis. The American journal of pathology, 2006, Volume: 169, Issue:4 Topics: Acrolein; Adenine; Animals; Antibodies, Monoclonal; Cell Transformation, Neoplastic; Chromosome Mapping; DNA; DNA Glycosylases; Gene Expression; Gene Library; Genes, Neoplasm; Genome; Guanine; Immunoprecipitation; Kidney; Kidney Neoplasms; Male; Mice; Mice, Knockout; Oxidation-Reduction; Oxidative Stress	2006
RNA polymerase II bypasses 8-oxoguanine in the presence of transcription elongation factor TFIIS. DNA repair, 2007, Jun-01, Volume: 6, Issue:6 Topics: Adenine; Base Sequence; DNA Damage; DNA Repair; Guanine; HeLa Cells; Humans; Models, Chemical; Models, Genetic; Molecular Sequence Data; Oxygen; RNA Polymerase II; Thymine; Transcription, Genetic; Transcriptional Elongation Factors	2007
Unnatural substrates reveal the importance of 8-oxoguanine for in vivo mismatch repair by MutY. Nature chemical biology, 2008, Volume: 4, Issue:1 Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenine; Base Pairing; Base Sequence; Deoxyguanosine; DNA Damage; DNA Glycosylases; DNA Mismatch Repair; Escherichia coli; Guanine; Kinetics; Molecular Sequence Data; Oligonucleotides; Plasmids; Substrate Specificity	2008
Inhibition of DNA replication fork progression and mutagenic potential of 1, N6-ethenoadenine and 8-oxoguanine in human cell extracts. Nucleic acids research, 2008, Volume: 36, Issue:4 Topics: Adenine; Cell Extracts; Cell Line; DNA Damage; DNA Replication; DNA-Directed DNA Polymerase; Electrophoresis, Gel, Two-Dimensional; Genetic Vectors; Guanine; HeLa Cells; Humans; Mutagenesis	2008
Postmortem miscoding lesions in sequence analysis of human ancient mitochondrial DNA. Journal of molecular evolution, 2009, Volume: 68, Issue:1 Topics: Adenine; Cytosine; DNA Damage; DNA, Mitochondrial; Guanine; Humans; Sequence Analysis; Thymine	2009
Flexibility promotes fidelity. Structure (London, England : 1993), 2009, May-13, Volume: 17, Issue:5 Topics: Adenine; Animals; Base Pair Mismatch; DNA Mismatch Repair; DNA-Directed DNA Polymerase; Guanine; Humans	2009
Molecular basis of transcriptional mutagenesis at 8-oxoguanine. The Journal of biological chemistry, 2009, Nov-13, Volume: 284, Issue:46 Topics: Adenine; Crystallography, X-Ray; DNA, Fungal; Guanine; Mutagenesis; Protein Conformation; RNA Polymerase II; RNA, Fungal; Saccharomyces cerevisiae; Transcription, Genetic	2009
Effects of base excision repair proteins on mutagenesis by 8-oxo-7,8-dihydroguanine (8-hydroxyguanine) paired with cytosine and adenine. DNA repair, 2010, May-04, Volume: 9, Issue:5 Topics: Adenine; Base Sequence; Cell Line; Cytosine; Deoxyguanine Nucleotides; DNA; DNA Glycosylases; DNA Repair; Gene Knockdown Techniques; Guanine; Humans; Mutagenesis; Mutation; Plasmids; RNA, Small Interfering	2010
Porphyromonas gingivalis mutY is involved in the repair of oxidative stress-induced DNA mispairing. Molecular oral microbiology, 2011, Volume: 26, Issue:3 Topics: Adenine; Bacteriological Techniques; Base Pair Mismatch; Base Sequence; Conserved Sequence; DNA Damage; DNA Glycosylases; DNA Mismatch Repair; Glutamine; Guanine; Humans; Hydrogen Peroxide; Mutagenesis, Insertional; Mutagenesis, Site-Directed; Mutation; Oxidants; Oxidative Stress; Plasmids; Porphyromonas gingivalis; Reverse Transcriptase Polymerase Chain Reaction; Valine	2011
RNA oxidation adducts 8-OHG and 8-OHA change with Aβ42 levels in late-stage Alzheimer's disease. PloS one, 2011, Volume: 6, Issue:9 Topics: Adenine; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Brain; Case-Control Studies; DNA Damage; Enzyme-Linked Immunosorbent Assay; Female; Gas Chromatography-Mass Spectrometry; Guanine; Humans; Male; Neurofibrillary Tangles; Oxidation-Reduction; Plaque, Amyloid; RNA	2011
Excited state proton-coupled electron transfer in 8-oxoG-C and 8-oxoG-A base pairs: a time dependent density functional theory (TD-DFT) study. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2013, Volume: 12, Issue:8 Topics: Adenine; Base Pairing; Cytosine; DNA; Electrons; Guanine; Models, Molecular; Protons; Quantum Theory	2013
Kinetic mechanism of nick sealing by T4 RNA ligase 2 and effects of 3'-OH base mispairs and damaged base lesions. RNA (New York, N.Y.), 2013, Volume: 19, Issue:12 Topics: Adenine; Apurinic Acid; Base Pairing; Base Sequence; Escherichia coli; Guanine; Kinetics; RNA Ligase (ATP); RNA, Double-Stranded; Viral Proteins	2013
Lipid peroxidation product 4-hydroxy-2-nonenal modulates base excision repair in human cells. DNA repair, 2014, Volume: 22 Topics: Adenine; Aldehydes; Cell Line; Cytosine; DNA Breaks, Single-Stranded; DNA Glycosylases; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; Guanine; Humans; Lipid Peroxidation	2014
Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide. Nature, 2015, Jan-29, Volume: 517, Issue:7536 Topics: Adenine; Base Pairing; Catalytic Domain; Crystallography, X-Ray; Cytosine; Cytotoxins; Deoxyguanine Nucleotides; DNA; DNA Damage; DNA Polymerase beta; DNA Repair; DNA Replication; Guanine; Humans; Hydrogen Bonding; Kinetics; Models, Molecular; Molecular Conformation; Mutagenesis; Neoplasms; Oxidation-Reduction; Oxidative Stress; Static Electricity; Substrate Specificity; Time Factors	2015
Simultaneous Detection of 3-Nitrotyrosine and 3-Nitro-4-hydroxyphenylacetic Acid in Human Urine by Online SPE LC-MS/MS and Their Association with Oxidative and Methylated DNA Lesions. Chemical research in toxicology, 2015, May-18, Volume: 28, Issue:5 Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenine; Adult; Chromatography, High Pressure Liquid; Chromatography, Liquid; Deoxyguanosine; Dimethylnitrosamine; DNA Methylation; Guanine; Humans; Limit of Detection; Middle Aged; Nitrophenols; Oxidation-Reduction; Phenylacetates; Solid Phase Extraction; Tandem Mass Spectrometry; Tyrosine; Young Adult	2015
Gum acacia mitigates genetic damage in adenine-induced chronic renal failure in rats. European journal of clinical investigation, 2015, Volume: 45, Issue:12 Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenine; Animals; Comet Assay; Deoxyguanosine; DNA Damage; Guanine; Guanosine; Gum Arabic; Kidney Failure, Chronic; Kidney Function Tests; Male; Random Allocation; Rats, Wistar; Renal Agents	2015
Structure and stereochemistry of the base excision repair glycosylase MutY reveal a mechanism similar to retaining glycosidases. Nucleic acids research, 2016, Jan-29, Volume: 44, Issue:2 Topics: Adenine; Bacterial Proteins; Catalysis; Catalytic Domain; DNA Glycosylases; DNA Repair; Geobacillus stearothermophilus; Guanine; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Tyrosine	2016
Inflammation increases oxidative DNA damage repair and stimulates preneoplastic changes in colons of newborn rats. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2016, Volume: 67, Issue:2 Topics: Adenine; Animals; Animals, Newborn; Arachidonate 12-Lipoxygenase; Colon; Colonic Neoplasms; Cyclooxygenase 2; Cytosine; DNA Damage; DNA Repair; Escherichia coli; Guanine; Inflammation; Lipopolysaccharides; Oxidative Stress; Precancerous Conditions; Rats, Wistar; Salmonella typhimurium	2016
Structure-Activity Relationships Reveal Key Features of 8-Oxoguanine: A Mismatch Detection by the MutY Glycosylase. ACS chemical biology, 2017, 09-15, Volume: 12, Issue:9 Topics: Adenine; Base Pair Mismatch; DNA Glycosylases; DNA Repair; Escherichia coli; Guanine; Models, Molecular; Substrate Specificity	2017
Reverse Transcription Past Products of Guanine Oxidation in RNA Leads to Insertion of A and C opposite 8-Oxo-7,8-dihydroguanine and A and G opposite 5-Guanidinohydantoin and Spiroiminodihydantoin Diastereomers. Biochemistry, 2017, 09-26, Volume: 56, Issue:38 Topics: Adenine; Guanidines; Guanine; Guanosine; Hydantoins; Kinetics; Oxidation-Reduction; Reverse Transcription; RNA; RNA-Directed DNA Polymerase; Spiro Compounds; Stereoisomerism	2017
Solid-State Nanopore Analysis of Diverse DNA Base Modifications Using a Modular Enzymatic Labeling Process. Nano letters, 2017, 11-08, Volume: 17, Issue:11 Topics: Adenine; Base Pair Mismatch; Biosensing Techniques; DNA; DNA Damage; DNA Repair; Epigenesis, Genetic; Guanine; Humans; Models, Molecular; Nanopores; Nanotechnology; Neoplasms; Uracil	2017
Single molecule glycosylase studies with engineered 8-oxoguanine DNA damage sites show functional defects of a MUTYH polyposis variant. Nucleic acids research, 2019, 04-08, Volume: 47, Issue:6 Topics: Adenine; Adenomatous Polyposis Coli; Animals; Colorectal Neoplasms; DNA Damage; DNA Glycosylases; Escherichia coli; Genomic Instability; Guanine; Humans; Mice; Mutation; Oxidative Stress	2019
Unique Hydrogen Bonding of Adenine with the Oxidatively Damaged Base 8-Oxoguanine Enables Specific Recognition and Repair by DNA Glycosylase MutY. Journal of the American Chemical Society, 2020, 12-02, Volume: 142, Issue:48 Topics: Adenine; Base Pairing; Catalysis; Catalytic Domain; DNA; DNA Glycosylases; DNA Repair; Escherichia coli; Guanine; Hydrogen Bonding; Hydrolysis; Models, Molecular; Structure-Activity Relationship; Substrate Specificity	2020
Insights into the mismatch discrimination mechanism of Y-family DNA polymerase Dpo4. The Biochemical journal, 2021, 05-14, Volume: 478, Issue:9 Topics: Adenine; Amino Acid Sequence; Archaeal Proteins; Binding Sites; Cloning, Molecular; Crystallography, X-Ray; DNA Polymerase beta; Escherichia coli; Gene Expression; Genetic Vectors; Guanine; Kinetics; Models, Molecular; Nucleic Acid Conformation; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Sulfolobus solfataricus; Thermodynamics	2021
Structure of the mammalian adenine DNA glycosylase MUTYH: insights into the base excision repair pathway and cancer. Nucleic acids research, 2021, 07-09, Volume: 49, Issue:12 Topics: Adenine; Adenomatous Polyposis Coli; Amino Acid Motifs; Animals; DNA; DNA Glycosylases; DNA Repair; DNA Replication; Guanine; Humans; Mice; Models, Molecular; Mutation; Proliferating Cell Nuclear Antigen; Zinc	2021
Single molecule analysis indicates stimulation of MUTYH by UV-DDB through enzyme turnover. Nucleic acids research, 2021, 08-20, Volume: 49, Issue:14 Topics: Adenine; Animals; DNA Damage; DNA Glycosylases; DNA Repair; DNA Replication; Guanine; Hydrocarbons, Chlorinated; Mice; Oxidative Stress; Single Molecule Imaging	2021