adenine has been researched along with 7-methylguanine in 55 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (38.18) | 18.7374 |
| 1990's | 17 (30.91) | 18.2507 |
| 2000's | 9 (16.36) | 29.6817 |
| 2010's | 8 (14.55) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liszewski, MK; Munns, TW; Oberst, RJ; Sims, HF | 1 |
| Ahnström, G; Eizirik, DL; Sandler, S; Welsh, M | 1 |
| Cushnir, JR; Farmer, PB; Lamb, JH; Parry, A | 1 |
| Correa, P; Glogowski, J; Stillwell, WG; Tannenbaum, SR; Wishnok, JS; Xu, HX | 1 |
| Chakravarti, D; Ibeanu, GC; Mitra, S; Tano, K | 1 |
| Correa, P; Glogowski, J; Montes, G; Stillwell, WG; Tannenbaum, SR; Wishnok, JS; Xu, HX; Zavala, D | 1 |
| Berdal, KG; Bjelland, S; Bjørås, M; Seeberg, E | 1 |
| Hanawalt, PC; Scicchitano, DA | 1 |
| Lawrence, CW; Nisson, PE | 1 |
| Backendorf, C; Kaina, B; Thielmann, HW; Van de Putte, P; Van Zeeland, AA | 1 |
| Bailey, E; Farmer, PB; Shuker, DE | 1 |
| D'Ambrosio, SM; Wani, AA | 1 |
| Helland, DE; Kleppe, K; Male, R | 1 |
| Briscoe, WT; Cotter, LE | 1 |
| Cathcart, R; Goldthwait, DA | 1 |
| Achwal, CW; Chandra, HS; Iyer, CA | 1 |
| Bresil, H; Cooper, DP; Margison, GP; Montesano, R; O'Connor, PJ; Planche-Martel, G; Smith, RA | 1 |
| Huang, SS; Pontzer, NJ; Shaikh, B | 1 |
| Aurich, O; Heindorff, K; Kaina, B | 1 |
| Alekandrov, VA; Anisimov, VN; Bespalov, VG; Korsakov, MV; Likhachev, AJ; Napalkov, NP; Ovsyannikov, AI; Popovich, IG; Tomatis, L | 1 |
| Margison, GP; Pegg, AE | 1 |
| Goldthwait, DA; Thomas, L; Yang, CH | 1 |
| Hjelmgren, T; Jacobsson, A; Lindahl, T; Olsson, M; Rydberg, B | 1 |
| Barrows, LR; Magee, PN | 1 |
| Kerler, R; Rabes, HM; Rode, G; Wilhelm, R | 1 |
| Brent, TP; Gallagher, PE | 1 |
| Abanobi, SE; Columbano, A; Mulivor, RA; Rajalakshmi, S; Sarma, DS | 1 |
| Scicchitano, DA; Sitaram, A; Wang, W | 1 |
| Brooks, C; Mitra, S; Roy, R | 1 |
| Aquilina, G; Bignami, M; Biondo, R; Dogliotti, E | 1 |
| Boosalis, MS; Chen, BJ; Deng, Z; Engelward, BP; Samson, LD; Siciliano, MJ | 1 |
| Chen, FX; Church, K; Encell, L; Gold, B; Mehta, P; Shuker, DE; Williams, J | 1 |
| Holmquist, GP; O'Connor, TR; Ye, N | 1 |
| Dobrzańska, M; Kraszewska, E; Tudek, B | 1 |
| Calléja, F; Jansen, JG; Laval, F; van Zeeland, AA; Vrieling, H | 1 |
| Augusto, O; Hix, S | 1 |
| Honsho, A; Ide, H; Kobayashi, M; Masaoka, A; Ohyama, Y; Terato, H | 1 |
| Asaeda, A; Asagoshi, K; Ide, H; Kubo, K; Matsuyama, S; Murakami, A; Takamori, Y; Tano, K | 1 |
| Graziewicz, M; Kazanova, O; Laval, J; Obtułowicz, T; Tudek, B; Zastawny, TH | 1 |
| Engelward, BP; Smith, SA | 1 |
| Engelward, BP; Gold, B; Magnotti, M; Millas, T; Plosky, B; Samson, L; Schlaen, B; Schor, J; Scicchitano, DA | 1 |
| Chen, FX; Dande, P; Fronza, G; Gold, B; Settles, S; Shah, D; Varadarajan, S | 1 |
| Arris, CA; Calvert, HA; Canan-Koch, S; Curtin, NJ; Durkacz, BW; Hostomsky, Z; Kyle, S; Newell, DR; Wang, LZ; Webber, SE; Yiakouvaki, A | 1 |
| Connor, EE; Wilson, JJ; Wyatt, MD | 1 |
| Bogdanffy, MS; Frame, SR; Mathison, BH | 1 |
| Chadt, J; Nilsson, R; Sykora, D; Vodicka, P | 1 |
| Delaney, JC; Essigmann, JM; Kartalou, M; Lee, CY; Lingaraju, GM; Maor-Shoshani, A; Samson, LD | 1 |
| Chen, M; Lee, JK; Michelson, AZ; Wang, K | 1 |
| Chao, MR; Hu, CW | 1 |
| Chao, MR; Chen, JL; Hu, CW; Lee, H; Li, YJ | 1 |
| Chao, MR; Chen, JL; Hsu, YW; Hu, CW; Tam, LM | 1 |
| Eichman, BF; Mullins, EA; Rubinson, EH | 1 |
| Chao, MR; Hsu, YW; Hu, CW; Lin, JH; Liu, HH | 1 |
| Ko, T; Li, M; Li, S | 1 |
| Bobrowska-Korczak, B; Gątarek, P; Giebułtowicz, J; Kałużna-Czaplińska, J; Rosiak, A | 1 |
1 review(s) available for adenine and 7-methylguanine
| Article | Year |
|---|---|
Enhanced repair of O6-alkylguanine in mammalian tissues.
Topics: 2-Acetylaminofluorene; Adenine; Aflatoxin B1; Aflatoxins; Alkylating Agents; Alkylation; Animals; Carcinogens; Cricetinae; Dimethylnitrosamine; DNA; DNA Repair; Dose-Response Relationship, Drug; Gerbillinae; Guanine; Hepatectomy; Liver; Methylnitrosourea; Mice; Rats; Rodentia; Species Specificity | 1984 |
54 other study(ies) available for adenine and 7-methylguanine
| Article | Year |
|---|---|
Antibody-nucleic acid complexes. Immunospecific recognition of 7-methylguanine- and N6-methyladenine-containing 5'-terminal oligonucleotides of mRNA.
Topics: Adenine; Adenoviruses, Human; Antigen-Antibody Complex; Cell Line; Cell Transformation, Viral; Guanine; Humans; Oligoribonucleotides; RNA, Messenger | 1979 |
Exposure of pancreatic islets to different alkylating agents decreases mitochondrial DNA content but only streptozotocin induces long-lasting functional impairment of B-cells.
Topics: Adenine; Alkylating Agents; Animals; Cytochrome b Group; DNA; Dose-Response Relationship, Drug; Glucagon; Glucose; Guanine; Immunoblotting; Insulin; Islets of Langerhans; Male; Methyl Methanesulfonate; Methylnitrosourea; Mice; Mitochondria; RNA, Messenger; Streptozocin | 1991 |
Tandem mass spectrometric approaches for determining exposure to alkylating agents.
Topics: Adenine; Alkylating Agents; Environmental Monitoring; Guanine; Humans; Mass Spectrometry | 1991 |
Comparison of urinary nitrate, N-nitrosoproline, 7-methylguanine and 3-methyladenine levels in a human population at risk for gastric cancer.
Topics: Adenine; Guanine; Humans; Nitrates; Nitrosamines; Risk; Stomach Neoplasms | 1991 |
Cloning and expression in Escherichia coli of a human cDNA encoding the DNA repair protein N-methylpurine-DNA glycosylase.
Topics: Adenine; Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Blotting, Southern; Cloning, Molecular; DNA; DNA Glycosylases; DNA Repair; Escherichia coli; Genes, Bacterial; Guanine; HeLa Cells; Humans; Molecular Sequence Data; N-Glycosyl Hydrolases; Rats; Restriction Mapping; RNA, Messenger; Sequence Homology, Nucleic Acid | 1991 |
Urinary excretion of nitrate, N-nitrosoproline, 3-methyladenine, and 7-methylguanine in a Colombian population at high risk for stomach cancer.
Topics: Adenine; Colombia; Guanine; Humans; Nitrates; Nitrosamines; Regression Analysis; Risk Factors; Stomach Neoplasms | 1991 |
Cloning and expression in Escherichia coli of a gene for an alkylbase DNA glycosylase from Saccharomyces cerevisiae; a homologue to the bacterial alkA gene.
Topics: Adenine; Amino Acid Sequence; Base Sequence; Cloning, Molecular; DNA Glycosylases; DNA Repair; Drug Resistance; Escherichia coli; Gene Expression; Genes, Bacterial; Genes, Fungal; Guanine; Methyl Methanesulfonate; Molecular Sequence Data; N-Glycosyl Hydrolases; Open Reading Frames; Restriction Mapping; Saccharomyces cerevisiae; Sequence Homology, Nucleic Acid | 1990 |
Repair of N-methylpurines in specific DNA sequences in Chinese hamster ovary cells: absence of strand specificity in the dihydrofolate reductase gene.
Topics: Adenine; Animals; Cell Line; Cricetinae; Deoxyribonucleases, Type II Site-Specific; Dimethyl Sulfoxide; DNA; DNA Damage; DNA Probes; DNA Repair; Electrophoresis, Agar Gel; Exons; Guanine; Hot Temperature; Hydrolysis; Nucleic Acid Hybridization; RNA Probes; Sulfuric Acid Esters; Tetrahydrofolate Dehydrogenase; Transcription, Genetic | 1989 |
The isolation and characterization of an alkylating-agent-sensitive yeast mutant, ngs1.
Topics: Adenine; Alkylating Agents; DNA Repair; Genes, Fungal; Guanine; Methylnitronitrosoguanidine; Mutation; Saccharomyces cerevisiae; Sulfuric Acid Esters | 1986 |
Transfer of human genes conferring resistance to methylating mutagens, but not to UV irradiation and cross-linking agents, into Chinese hamster ovary cells.
Topics: Adenine; Alkylating Agents; Animals; Cricetinae; Cross-Linking Reagents; DNA Repair; Genes; Guanine; Humans; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Transfection; Ultraviolet Rays | 1987 |
Excretion of methylated nucleic acid bases as an indicator of exposure to nitrosatable drugs.
Topics: Adenine; Animals; Female; Guanine; Methylation; Nitroso Compounds; Nucleic Acids; Rats | 1987 |
Specific DNA alkylation damage and its repair in carcinogen-treated rat liver and brain.
Topics: Adenine; Alkylating Agents; Animals; Brain; Carcinogens; DNA; DNA Repair; Guanine; Hydrogen-Ion Concentration; Hydrolysis; Liver; Male; Methyl Methanesulfonate; Methylnitrosourea; Rats; Rats, Inbred Strains | 1986 |
Purification and characterization of 3-methyladenine-DNA glycosylase from calf thymus.
Topics: Adenine; Animals; Cattle; Chemical Phenomena; Chemistry, Physical; Chromatin; DNA Glycosylases; Guanine; Hot Temperature; Isoelectric Point; Kinetics; Molecular Weight; N-Glycosyl Hydrolases; Substrate Specificity; Sulfhydryl Compounds; Thymus Gland | 1985 |
DNA sequence has an effect on the extent and kinds of alkylation of DNA by a potent carcinogen.
Topics: Adenine; Alkylation; Animals; Base Sequence; Cattle; DNA; Guanine; Methylnitrosourea; Polydeoxyribonucleotides; Structure-Activity Relationship; Thymus Gland; Tritium | 1985 |
Enzymatic excision of 3-methyladenine and 7-methylguanine by a rat liver nuclear fraction.
Topics: Adenine; Animals; Cell Nucleus; Chromatography, Affinity; DNA Glycosylases; Endonucleases; Guanine; Kinetics; Liver; Molecular Weight; N-Glycosyl Hydrolases; Rats; Substrate Specificity | 1981 |
Immunochemical evidence for the presence of 5mC, 6mA and 7mG in human, Drosophila and mealybug DNA.
Topics: 5-Methylcytosine; Adenine; Animals; Antibodies; Chemical Phenomena; Chemistry; Cytosine; DNA; Drosophila melanogaster; Female; Guanine; Humans; Immunochemistry; Insecta; Male; Placenta; Rats; Species Specificity; Spermatozoa | 1983 |
Urinary excretion of methylated purines and 1-methyl-nicotinamide following administration of methylating carcinogens.
Topics: 1,2-Dimethylhydrazine; Adenine; Alkylating Agents; Animals; Carcinogens; Dimethylhydrazines; Dimethylnitrosamine; Guanine; Male; Methyl Methanesulfonate; Methylation; Methylnitronitrosoguanidine; Niacinamide; Rats | 1980 |
O6-methylguanine, but not N7-methylguanine or N3-methyladenine, induces gene mutations, sister-chromatid exchanges and chromosomal aberrations in Chinese hamster cells.
Topics: Adenine; Animals; Cells, Cultured; Chromosome Aberrations; Cricetinae; Crossing Over, Genetic; Dose-Response Relationship, Drug; Guanine; Karyotyping; Mutation; Sister Chromatid Exchange | 1983 |
Persistence of methylated purines in the DNA of various rat fetal and maternal tissues and carcinogenesis in the offspring following a single transplacental dose of N-methyl-N-nitrosourea.
Topics: Adenine; Animals; Brain; DNA; Female; Fetus; Guanine; Kidney; Liver; Methylation; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Placenta; Pregnancy; Purines; Rats; Time Factors | 1983 |
Enzymatic release of 7-methylguanine from methylated DNA by rodent liver extracts.
Topics: Adenine; Animals; Cattle; Cricetinae; DNA; DNA Glycosylases; Escherichia coli; Guanine; Kinetics; Liver; Methylation; N-Glycosyl Hydrolases; Rats; Thymus Gland | 1981 |
Two DNA glycosylases in Escherichia coli which release primarily 3-methyladenine.
Topics: Adenine; Bacterial Proteins; DNA Glycosylases; Escherichia coli; Guanine; Hot Temperature; Isoelectric Focusing; Kinetics; Molecular Weight; N-Glycosyl Hydrolases; Substrate Specificity | 1982 |
Cellular defense mechanisms against alkylation of DNA.
Topics: Adenine; Alkylation; DNA Glycosylases; DNA Repair; Escherichia coli; Guanine; Methyltransferases; Mutation; N-Glycosyl Hydrolases; S-Adenosylmethionine | 1982 |
Nonenzymatic methylation of DNA by S-adenosylmethionine in vitro.
Topics: Adenine; Animals; Cattle; Chromatography, High Pressure Liquid; DNA; DNA Repair; Guanine; In Vitro Techniques; Methylation; S-Adenosylmethionine; Scintillation Counting; Spectrophotometry, Ultraviolet | 1982 |
Dose- and cell cycle-dependent O6-methylguanine elimination from DNA in regenerating rat liver after [14C]dimethylnitrosamine injection.
Topics: Adenine; Animals; Dimethylnitrosamine; DNA; DNA Repair; Dose-Response Relationship, Drug; Guanine; Interphase; Liver; Liver Regeneration; Male; Rats | 1982 |
Partial purification and characterization of 3-methyladenine-DNA glycosylase from human placenta.
Topics: Adenine; Chromatography, High Pressure Liquid; DNA Glycosylases; Female; Guanine; Humans; N-Glycosyl Hydrolases; Placenta; Pregnancy; Substrate Specificity | 1982 |
In vivo replication of hepatic deoxyribonucleic acid of rats treated with dimethylnitrosamine: presence of dimethylnitrosamine-induced O6-methylguanine, N7-methylguanine, and N3-methyladenine in the replicated hybrid deoxyribonucleic acid.
Topics: Adenine; Animals; Dimethylnitrosamine; DNA Replication; Guanine; Liver; Male; Nucleic Acid Hybridization; Rats | 1980 |
3-Methyladenine and 7-methylguanine exhibit no preferential removal from the transcribed strand of the dihydrofolate reductase gene in Chinese hamster ovary B11 cells.
Topics: Adenine; Animals; Autoradiography; CHO Cells; Cricetinae; DNA Damage; Guanine; Tetrahydrofolate Dehydrogenase; Transcription, Genetic | 1995 |
Purification and biochemical characterization of recombinant N-methylpurine-DNA glycosylase of the mouse.
Topics: Adenine; Amino Acid Sequence; Animals; DNA; DNA Glycosylases; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Guanine; Hydrogen-Ion Concentration; Kinetics; Magnesium Chloride; Methylation; Mice; Molecular Sequence Data; N-Glycosyl Hydrolases; Recombinant Proteins; Sodium Chloride; Spermine; Substrate Specificity | 1994 |
Genetic consequences of tolerance to methylation DNA damage in mammalian cells.
Topics: Adenine; Adenine Phosphoribosyltransferase; Animals; Aza Compounds; Base Sequence; Cell Survival; CHO Cells; Cricetinae; DNA; DNA Damage; Drug Resistance; Guanine; Methylation; Methylnitrosourea; Molecular Sequence Data; Mutation; Ouabain; Thioguanine | 1993 |
Cloning and characterization of a mouse 3-methyladenine/7-methyl-guanine/3-methylguanine DNA glycosylase cDNA whose gene maps to chromosome 11.
Topics: Adenine; Amino Acid Sequence; Animals; Base Sequence; Blotting, Southern; Cell Nucleus; Chromosome Mapping; Chromosomes; Cloning, Molecular; DNA; DNA Glycosylases; DNA Repair; Escherichia coli; Gene Expression; Guanine; Humans; Mice; Molecular Sequence Data; N-Glycosyl Hydrolases; Rats; RNA, Messenger; Sequence Homology, Amino Acid | 1993 |
The design of agents to control DNA methylation adducts. Enhanced major groove methylation of DNA by an N-methyl-N-nitrosourea functionalized phenyl neutral red intercalator.
Topics: Adenine; Circular Dichroism; DNA Adducts; DNA Methylation; Drug Design; Ethidium; Guanine; Intercalating Agents; Methylnitrosourea; Neutral Red; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1996 |
Heterogeneous repair of N-methylpurines at the nucleotide level in normal human cells.
Topics: Adenine; Base Sequence; Chromatin; DNA Adducts; DNA Damage; DNA Footprinting; DNA Glycosylases; DNA Repair; Exons; Fibroblasts; Guanine; Half-Life; Humans; Male; Molecular Sequence Data; N-Glycosyl Hydrolases; Phosphoglycerate Kinase; Promoter Regions, Genetic; Sulfuric Acid Esters | 1998 |
Tobacco BY-2 cells excise both 3-methyladenine and 7-methylguanine from methylated DNA.
Topics: Adenine; Animals; Cattle; Cell Line; Chromatography, High Pressure Liquid; DNA; DNA Glycosylases; DNA Methylation; Guanine; Methyl Methanesulfonate; Methylnitrosourea; Mutagens; N-Glycosyl Hydrolases; Nicotiana; Plants, Toxic | 1998 |
Modulation of the toxic and mutagenic effects induced by methyl methanesulfonate in Chinese hamster ovary cells by overexpression of the rat N-alkylpurine-DNA glycosylase.
Topics: Adenine; Alkylating Agents; Animals; Base Pair Mismatch; CHO Cells; Cricetinae; Cricetulus; DNA Damage; DNA Glycosylases; DNA Ligases; DNA Methylation; DNA Repair; Enzyme Induction; Frameshift Mutation; Guanine; Hypoxanthine Phosphoribosyltransferase; Methyl Methanesulfonate; Mutagenesis; Mutagens; N-Glycosyl Hydrolases; Rats; Recombinant Fusion Proteins; Transfection | 1999 |
DNA methylation by tert-butyl hydroperoxide-iron (II): a role for the transition metal ion in the production of DNA base adducts.
Topics: Adenine; Animals; Cattle; Chelating Agents; Copper; DNA Adducts; DNA Methylation; Electron Spin Resonance Spectroscopy; Free Radicals; Guanine; Iron; Molecular Structure; tert-Butylhydroperoxide | 1999 |
Enzymatic repair of 5-formyluracil. I. Excision of 5-formyluracil site-specifically incorporated into oligonucleotide substrates by alka protein (Escherichia coli 3-methyladenine DNA glycosylase II).
Topics: Adenine; Base Pair Mismatch; DNA Damage; DNA Glycosylases; DNA Repair; Escherichia coli; Guanine; Kinetics; Magnetic Resonance Spectroscopy; Methylnitronitrosoguanidine; Molecular Structure; N-Glycosyl Hydrolases; Oligodeoxyribonucleotides; Pentoxyl; Substrate Specificity; Thymine; Uracil | 1999 |
Substrate specificity of human methylpurine DNA N-glycosylase.
Topics: Adenine; Binding, Competitive; DNA; DNA Glycosylases; DNA Repair; Guanine; Guanosine; Humans; Hypoxanthine; Kinetics; N-Glycosyl Hydrolases; Oligonucleotides; Recombinant Proteins; Substrate Specificity | 2000 |
Mutagenic specificity of imidazole ring-opened 7-methylpurines in M13mp18 phage DNA.
Topics: Adenine; Base Sequence; DNA Damage; DNA Methylation; DNA-Formamidopyrimidine Glycosylase; DNA, Viral; Escherichia coli; Escherichia coli Proteins; Guanine; Imidazoles; Lac Operon; Molecular Sequence Data; Mutagens; Mutation; N-Glycosyl Hydrolases; Pyrimidines; Transfection | 1999 |
In vivo repair of methylation damage in Aag 3-methyladenine DNA glycosylase null mouse cells.
Topics: Adenine; Animals; Cell Line; DNA Adducts; DNA Damage; DNA Glycosylases; DNA Methylation; DNA Repair; DNA Replication; Gene Deletion; Genotype; Guanine; Guanosine; Methylnitrosourea; Mice; Mice, Knockout; N-Glycosyl Hydrolases | 2000 |
Base excision repair and nucleotide excision repair contribute to the removal of N-methylpurines from active genes.
Topics: Adenine; Animals; Cells, Cultured; DNA Damage; DNA Glycosylases; DNA Repair; DNA Replication; Guanine; Mice; Mice, Knockout; N-Glycosyl Hydrolases; Phenotype; Pyrimidine Dimers; Tetrahydrofolate Dehydrogenase; Transcription, Genetic | 2002 |
DNA damage and cytotoxicity induced by minor groove binding methyl sulfonate esters.
Topics: Adenine; Anti-Bacterial Agents; Base Sequence; DNA Adducts; DNA Damage; DNA Fragmentation; DNA Methylation; DNA Repair; DNA, Bacterial; Escherichia coli; Esters; Guanine; Mesylates; Molecular Sequence Data; Netropsin; Nucleic Acid Conformation; Protein Binding | 2003 |
Novel poly(ADP-ribose) polymerase-1 inhibitor, AG14361, restores sensitivity to temozolomide in mismatch repair-deficient cells.
Topics: Adenine; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Azulenes; Base Pair Mismatch; Benzodiazepines; Cell Division; Cell Line, Tumor; Cisplatin; Dacarbazine; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Genotype; Guanine; Humans; Models, Chemical; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Temozolomide | 2004 |
Effects of substrate specificity on initiating the base excision repair of N-methylpurines by variant human 3-methyladenine DNA glycosylases.
Topics: Adenine; Animals; DNA Damage; DNA Glycosylases; DNA Repair; Dose-Response Relationship, Drug; Genetic Engineering; Guanine; Humans; Methyl Methanesulfonate; Mutagens; Saccharomyces cerevisiae; Substrate Specificity | 2005 |
DNA methylation, cell proliferation, and histopathology in rats following repeated inhalation exposure to dimethyl sulfate.
Topics: Adenine; Administration, Inhalation; Alkylating Agents; Animals; Body Weight; Cell Proliferation; DNA; DNA Adducts; DNA Methylation; Guanine; Male; Methylation; Models, Biological; Mutagens; Olfactory Mucosa; Purines; Rats; Risk; Sulfuric Acid Esters | 2004 |
Monitoring of dimethyl sulphate-induced N3-methyladenine, N7-methylguanine and O(6)-methylguanine DNA adducts using reversed-phase high performance liquid chromatography and mass spectrometry.
Topics: Adenine; Animals; Chromatography, High Pressure Liquid; DNA; DNA Adducts; Guanine; Male; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Sulfuric Acid Esters; Testis | 2008 |
Recognition and processing of a new repertoire of DNA substrates by human 3-methyladenine DNA glycosylase (AAG).
Topics: Adenine; Base Sequence; Catalysis; Catalytic Domain; DNA; DNA Damage; DNA Glycosylases; DNA Repair; DNA, Single-Stranded; Electrophoretic Mobility Shift Assay; Guanine; Humans; Kinetics; Models, Molecular; Molecular Structure; Oligonucleotides; Protein Binding; Protein Structure, Tertiary; Sequence Deletion; Substrate Specificity | 2009 |
Gas-phase studies of purine 3-methyladenine DNA glycosylase II (AlkA) substrates.
Topics: Adenine; Catalytic Domain; DNA Glycosylases; Escherichia coli; Guanine; Protons; Purines; Stereoisomerism; Substrate Specificity; Temperature; Xanthine | 2012 |
Direct-acting DNA alkylating agents present in aqueous extracts of areca nut and its products.
Topics: Adenine; Alkylation; Animals; Areca; Cattle; Chromatography, Liquid; DNA; DNA Damage; Guanine; Molecular Structure; Nuts; Plant Extracts; Tandem Mass Spectrometry; Water | 2012 |
Optimization of global DNA methylation measurement by LC-MS/MS and its application in lung cancer patients.
Topics: Adenine; Adenocarcinoma; Aged; Carcinoma, Squamous Cell; Chromatography, Liquid; Deoxycytidine; DNA Methylation; DNA, Neoplasm; Female; Fungal Proteins; Guanine; Humans; Indicator Dilution Techniques; Limit of Detection; Lung Neoplasms; Male; Middle Aged; Reproducibility of Results; Single-Strand Specific DNA and RNA Endonucleases; Solid Phase Extraction; Tandem Mass Spectrometry; Tumor Microenvironment | 2013 |
Direct analysis of tobacco-specific nitrosamine NNK and its metabolite NNAL in human urine by LC-MS/MS: evidence of linkage to methylated DNA lesions.
Topics: Adenine; Adult; Biomarkers; Chromatography, Liquid; Cotinine; DNA Methylation; Guanine; Humans; Limit of Detection; Nicotine; Nitrosamines; Pyridines; Sensitivity and Specificity; Smoking; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2014 |
The substrate binding interface of alkylpurine DNA glycosylase AlkD.
Topics: Adenine; Catalytic Domain; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; Guanine; Models, Molecular; Mutation; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Substrate Specificity | 2014 |
Simultaneous Detection of 3-Nitrotyrosine and 3-Nitro-4-hydroxyphenylacetic Acid in Human Urine by Online SPE LC-MS/MS and Their Association with Oxidative and Methylated DNA Lesions.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenine; Adult; Chromatography, High Pressure Liquid; Chromatography, Liquid; Deoxyguanosine; Dimethylnitrosamine; DNA Methylation; Guanine; Humans; Limit of Detection; Middle Aged; Nitrophenols; Oxidation-Reduction; Phenylacetates; Solid Phase Extraction; Tandem Mass Spectrometry; Tyrosine; Young Adult | 2015 |
High-resolution Digital Mapping of N-Methylpurines in Human Cells Reveals Modulation of Their Induction and Repair by Nearest-neighbor Nucleotides.
Topics: Adenine; Cell Line; DNA Repair; Fibroblasts; Guanine; Humans; Sulfuric Acid Esters | 2015 |
Reduced levels of modified nucleosides in the urine of autistic children. Preliminary studies.
Topics: Adenine; Adenosine; Adolescent; Autistic Disorder; Child; Child, Preschool; Chromatography, Liquid; Female; Guanine; Guanosine; Humans; Male; Mass Spectrometry | 2019 |