adenine and 5'-methylthioadenosine

adenine has been researched along with 5'-methylthioadenosine in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199012 (48.00)18.7374
1990's3 (12.00)18.2507
2000's3 (12.00)29.6817
2010's7 (28.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Inoue, H; Ishida, H; Kasahara, S; Nagata, T; Nishikawa, S; Ohishi, K; Wakano, Y; Yamauchi, N1
Akaoka, I; Fujimori, S; Kamatani, N; Kaneko, K; Kumakawa, T1
Bottiglieri, T; Chanarin, I; Deacon, R; Lumb, M; Perry, J1
Blackwell, K; Emmerson, BT; Gordon, RB1
Krenitsky, TA; Miller, RL; Sabourin, CL1
Goldblum, RM; Mills, GC; Schmalstieg, FC1
Dainko, JL; Schlenk, F; Zydek-Cwick, CR1
Ekström, P; Kanje, M1
Boliska, SA; Bols, NC; Mosser, DD; Snyder, FF1
Carson, DA; Frincke, LA; Kamatani, N; Kubota, M; Willis, EH1
Ferro, AJ; MacDonald, MR; Vandenbark, AA1
Chun, BG; Kim, S; Paik, WK1
Eloranta, TO; Raina, AM; Tuomi, K1
Cartenì-Farina, M; Della Ragione, F; Galletti, P; Manna, C; Oliva, A1
Cartenì-Farina, M; Della Ragione, F; Galletti, P; Giordano, F; Manna, C; Oliva, A1
Avila, MA; Corrales, FJ; García-Trevijano, ER; Lu, SC; Mato, JM1
Batova, A; Carrera, CJ; Cottam, H; Diccianni, MB; Yu, AL; Yu, J1
Almo, SC; Fedorov, AA; Fedorov, E; Hermann, JC; Marti-Arbona, R; Raushel, FM; Shoichet, BK1
Basu, I; Belbin, TJ; Cassera, MB; Dong, X; Evans, GB; Guha, C; Hemeon, I; Locker, J; Merino, EF; Schramm, VL1
Anderson, PS; Hong-Geller, E; Martí-Arbona, R; Nowak-Lovato, KL; Teshima, M; Unkefer, CJ; Unkefer, PJ1
Almo, SC; Evans, GB; Haapalainen, AM; Schramm, VL; Thomas, K; Tyler, PC1
Bai, G; Liang, Q; Luo, G; Ma, J; Wang, Y; Ying, X1
Evans, GB; Guan, R; Schramm, VL; Tyler, PC1
Chen, Z; Jiang, D; Kang, X; Li, X; Wang, X; Wu, Y; Zhang, XC; Zhao, Y1
Banco, MT; Evans, GB; Kovalevsky, A; Mishra, V; Ostermann, A; Ronning, DR; Schrader, TE1

Reviews

1 review(s) available for adenine and 5'-methylthioadenosine

ArticleYear
Methylthioadenosine.
    The international journal of biochemistry & cell biology, 2004, Volume: 36, Issue:11

    Topics: Adenine; Animals; Apoptosis; Cell Differentiation; Deoxyadenosines; Gene Expression Regulation; Humans; Methionine; Neoplasms; Purines; S-Adenosylhomocysteine; Thionucleosides

2004

Other Studies

24 other study(ies) available for adenine and 5'-methylthioadenosine

ArticleYear
The role of 5'-methylthioadenosine on rat calvaria cell differentiation.
    Biochemical and biophysical research communications, 1992, Jan-31, Volume: 182, Issue:2

    Topics: Adenine; Adenosine; Alkaline Phosphatase; Animals; Bone and Bones; Cell Differentiation; Cell Division; Cells, Cultured; Deoxyadenosines; Kinetics; Osteopontin; Purine-Nucleoside Phosphorylase; Rats; Sialoglycoproteins; Thionucleosides

1992
Disturbance in the metabolism of 5'-methylthioadenosine and adenine in patients with neoplastic diseases, and in those with a deficiency in adenine phosphoribosyltransferase.
    Metabolism: clinical and experimental, 1991, Volume: 40, Issue:9

    Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Adult; Aged; Deoxyadenosines; Female; Humans; Leukemia; Male; Middle Aged; Neoplasms; Osmolar Concentration; Thionucleosides

1991
Methylthioadenosine serves as a single carbon source to the folate co-enzyme pool in rat bone marrow cells.
    Biochimica et biophysica acta, 1990, Jun-20, Volume: 1034, Issue:3

    Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Bone Marrow; Carbon; Deoxyadenosines; Folic Acid; Formates; Glycine; Guanine; Male; Methionine; Methionine Adenosyltransferase; Oxidation-Reduction; Rats; Rats, Inbred Strains; Serine; Thionucleosides

1990
Synthesis of purines in human lymphoblast cells deficient in methylthioadenosine phosphorylase activity.
    Biochimica et biophysica acta, 1987, Jan-19, Volume: 927, Issue:1

    Topics: Adenine; Adenosine; B-Lymphocytes; Cell Line; Deoxyadenosines; Humans; Kinetics; Leukemia, Lymphoid; Lymphocytes; Pentosyltransferases; Purine-Nucleoside Phosphorylase; Purines; T-Lymphocytes; Thionucleosides

1987
Trypanosoma cruzi adenine nucleoside phosphorylase. Purification and substrate specificity.
    Biochemical pharmacology, 1987, Feb-15, Volume: 36, Issue:4

    Topics: Adenine; Adenosine; Animals; Deoxyadenosines; Kinetics; Molecular Weight; Pentosyltransferases; Purine-Nucleoside Phosphorylase; Substrate Specificity; Thionucleosides; Trypanosoma cruzi

1987
Urinary purines and nucleosides in immune deficiencies.
    Annals of the New York Academy of Sciences, 1985, Volume: 451

    Topics: Adenine; Adenosine; Adenosine Deaminase; Adult; Child; Deoxyadenosines; Female; Humans; Immunologic Deficiency Syndromes; Inosine; Purine Nucleosides; Purines; Pyrimidine Nucleosides; Pyrimidines; S-Adenosylhomocysteine; Thionucleosides

1985
5'-Methylthioadenosine and related compounds as precursors of S-adenosylmethionine in yeast.
    Biochimica et biophysica acta, 1973, Sep-14, Volume: 320, Issue:2

    Topics: Adenine; Adenosine; Aerobiosis; Candida; Carbon Radioisotopes; Deoxyadenosines; Methionine; Optical Rotation; S-Adenosylmethionine; Spectrophotometry, Ultraviolet; Sulfides; Sulfur Radioisotopes; Thionucleosides; Time Factors

1973
Inhibition of fast axonal transport by erythro-9-[3-(2-hydroxynonyl)]adenine.
    Journal of neurochemistry, 1984, Volume: 43, Issue:5

    Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Axonal Transport; Cycloleucine; Deoxyadenosines; Rana esculenta; Rana temporaria; Sciatic Nerve; Thionucleosides

1984
The transfer of 5'-methylthioadenosine from B82 cells through the medium to CHW-1102 cells.
    Experimental cell research, 1983, Apr-15, Volume: 145, Issue:1

    Topics: Adenine; Adenosine; Animals; Cell Communication; Cell Line; Cricetinae; Culture Media; Deoxyadenosines; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Mitoguazone; Purine-Nucleoside Phosphorylase; Thionucleosides

1983
5'-Methylthioadenosine is the major source of adenine in human cells.
    Advances in experimental medicine and biology, 1984, Volume: 165 Pt B

    Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Cell Line; Cells, Cultured; Deoxyadenosines; Humans; Leukemia, Lymphoid; Purine-Nucleoside Phosphorylase; Thionucleosides

1984
Inactivation of S-adenosylhomocysteine hydrolase by 5'-deoxy-5'-methylthioadenosine.
    Biochemical and biophysical research communications, 1981, May-29, Volume: 100, Issue:2

    Topics: Adenine; Adenosine; Adenosylhomocysteinase; Deoxyadenosines; Erythrocytes; Humans; Hydrolases; In Vitro Techniques; Ribose; Thioglycosides; Thionucleosides

1981
Simple separation of adenine and adenosyl-sulfur compounds by high-performance liquid chromatography.
    Journal of chromatography, 1983, Jul-15, Volume: 264, Issue:2

    Topics: Adenine; Adenosine; Animals; Chromatography, High Pressure Liquid; Deoxyadenosines; Male; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides

1983
Uptake and utilization of 5'-methylthioadenosine by cultured baby-hamster kidney cells.
    The Biochemical journal, 1982, Jun-15, Volume: 204, Issue:3

    Topics: Adenine; Adenosine; Animals; Cell Division; Cell Line; Cricetinae; Deoxyadenosines; Kidney; Thionucleosides; Tubercidin

1982
Effect of 5'-methylthioadenosine on in vivo methyl esterification of human erythrocyte membrane proteins.
    FEBS letters, 1981, Apr-20, Volume: 126, Issue:2

    Topics: Adenine; Adenosine; Deoxyadenosines; Erythrocyte Membrane; Erythrocytes; Humans; Membrane Proteins; Methylation; Protein Methyltransferases; Protein O-Methyltransferase; Thionucleosides

1981
[Possible regulatory role of 5'-methylthioadenosine on enzymatic methyl esterification of membrane protein].
    Bollettino della Societa italiana di biologia sperimentale, 1981, Jun-15, Volume: 57, Issue:11

    Topics: Adenine; Adenosine; Deoxyadenosines; Erythrocytes; Humans; Membrane Proteins; Methylation; Protein O-Methyltransferase; S-Adenosylmethionine; Thionucleosides

1981
EFA (9-beta-D-erythrofuranosyladenine) is an effective salvage agent for methylthioadenosine phosphorylase-selective therapy of T-cell acute lymphoblastic leukemia with L-alanosine.
    Blood, 2006, Feb-01, Volume: 107, Issue:3

    Topics: Adenine; Alanine; Antibiotics, Antineoplastic; Cell Line, Tumor; Deoxyadenosines; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme Inhibitors; Erythroid Precursor Cells; Furans; Granulocyte Precursor Cells; Humans; Leukemia-Lymphoma, Adult T-Cell; Purine-Nucleoside Phosphorylase; Salvage Therapy; Thionucleosides

2006
Structure-based activity prediction for an enzyme of unknown function.
    Nature, 2007, Aug-16, Volume: 448, Issue:7155

    Topics: Adenine; Catalysis; Crystallography, X-Ray; Deamination; Deoxyadenosines; Enzymes; Homocysteine; Inosine; Models, Molecular; Nucleoside Deaminases; Protein Conformation; S-Adenosylhomocysteine; Structure-Activity Relationship; Substrate Specificity; Thermotoga maritima; Thionucleosides

2007
Growth and metastases of human lung cancer are inhibited in mouse xenografts by a transition state analogue of 5'-methylthioadenosine phosphorylase.
    The Journal of biological chemistry, 2011, Feb-11, Volume: 286, Issue:6

    Topics: Adenine; Adenosine; Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Deoxyadenosines; Humans; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Purine-Nucleoside Phosphorylase; Pyrrolidines; S-Adenosylmethionine; Thionucleosides; Transplantation, Heterologous; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays

2011
Identification of new ligands for the methionine biosynthesis transcriptional regulator (MetJ) by FAC-MS.
    Journal of molecular microbiology and biotechnology, 2012, Volume: 22, Issue:4

    Topics: Adenine; Bacterial Proteins; Binding Sites; Chromatography, Affinity; Cloning, Molecular; Deoxyadenosines; DNA, Bacterial; Escherichia coli; Gene Expression Regulation, Bacterial; Genes, Bacterial; Genetic Vectors; High-Throughput Screening Assays; Ligands; Methionine; Protein Binding; Repressor Proteins; S-Adenosylmethionine; Spectrometry, Mass, Electrospray Ionization; Thionucleosides; Time Factors; Transcription, Genetic

2012
Salmonella enterica MTAN at 1.36 Å resolution: a structure-based design of tailored transition state analogs.
    Structure (London, England : 1993), 2013, Jun-04, Volume: 21, Issue:6

    Topics: Adenine; Deoxyadenosines; Models, Molecular; N-Glycosyl Hydrolases; Polymers; Propylene Glycols; Protein Conformation; S-Adenosylhomocysteine; Salmonella enterica; Thionucleosides

2013
Identification and analysis of the constituents in an aqueous extract of Tricholoma matsutake by HPLC coupled with diode array detection/electrospray ionization mass spectrometry.
    Journal of food science, 2013, Volume: 78, Issue:8

    Topics: Adenine; Adenosine; Chromatography, High Pressure Liquid; Cytidine; Deoxyadenosines; Guanosine; Inosine; Phenylalanine; Riboflavin; Spectrometry, Mass, Electrospray Ionization; Thionucleosides; Tricholoma; Tryptophan; Tyrosine; Uridine; Water

2013
Thermodynamic analysis of transition-state features in picomolar inhibitors of human 5'-methylthioadenosine phosphorylase.
    Biochemistry, 2013, Nov-19, Volume: 52, Issue:46

    Topics: Adenine; Catalytic Domain; Deoxyadenosines; Enzyme Stability; Humans; Protein Structure, Tertiary; Purine-Nucleoside Phosphorylase; Pyrrolidines; Thermodynamics; Thionucleosides

2013
Crystal structure and biochemical studies of Brucella melitensis 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase.
    Biochemical and biophysical research communications, 2014, Apr-18, Volume: 446, Issue:4

    Topics: Adenine; Brucella melitensis; Brucellosis; Catalytic Domain; Crystallography, X-Ray; Deoxyadenosines; Kinetics; Models, Molecular; N-Glycosyl Hydrolases; Protein Conformation; Substrate Specificity; Thionucleosides

2014
Neutron structures of the Helicobacter pylori 5'-methylthioadenosine nucleosidase highlight proton sharing and protonation states.
    Proceedings of the National Academy of Sciences of the United States of America, 2016, 11-29, Volume: 113, Issue:48

    Topics: Adenine; Catalytic Domain; Crystallography, X-Ray; Deoxyadenosines; Formycins; Helicobacter pylori; Hydrogen Bonding; Models, Molecular; Neutrons; Protein Binding; Protons; Purine-Nucleoside Phosphorylase; Pyrrolidines; S-Adenosylhomocysteine; Substrate Specificity; Thionucleosides

2016