adenine and 3-deazaadenine

adenine has been researched along with 3-deazaadenine in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19902 (12.50)18.7374
1990's1 (6.25)18.2507
2000's8 (50.00)29.6817
2010's5 (31.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abdelrahman, A; Alksnis, E; Borrmann, T; Cristalli, G; Gorzalka, S; Knospe, M; Lambertucci, C; Müller, CE; Schiedel, AC; Volpini, R1
Borchardt, RT; Borcherding, DR; Keller, BT; Narayanan, SR; Scholtz, SA1
Allan, PW; Bennett, LL; Brockman, RW; Rose, LM; Shaddix, SC1
Brown, T; Cosstick, R; Ebel, S; Lever, C; Li, X1
Lan, T; McLaughlin, LW2
O'Daniel, PI; Salim, S; Seley, KL1
Kim, T; Kool, ET; Maki, AS1
Dhivant, S; Mitton, K; Ortiz, DO; Rogers, E; Shea, TB; Tjiattas, L1
Crey-Desbiolles, C; Kotera, M1
Hua, DH; Komoto, J; Lou, K; Ogawa, H; Sugiyama, K; Takata, Y; Takusagawa, F; Ueki, A; Yamada, T1
Ganguly, M; Gold, B; Marky, LA; Wang, RW1
Ceulemans, A; Dyubankova, N; Herdewijn, P; Lescrinier, E; Maiti, M; Michielssens, S1
Chen, Q; Liu, C; Schneller, SW; Yang, M1
Chandra, G; Chang, TS; Choi, S; Jang, JY; Jeong, LS; Kim, G; Lee, SK; Lee, Y; Moon, YW; Mulamoottil, VA; Nayak, A; Noh, M; Oh, K; Sahu, PK; Song, J1
Chen, Q; Liu, C; Schneller, SW1

Other Studies

16 other study(ies) available for adenine and 3-deazaadenine

ArticleYear
Structure-activity relationships of adenine and deazaadenine derivatives as ligands for adenine receptors, a new purinergic receptor family.
    Journal of medicinal chemistry, 2009, Oct-08, Volume: 52, Issue:19

    Topics: Adenine; Animals; Astrocytoma; Cell Line; Cell Line, Tumor; Cerebral Cortex; Humans; Ligands; Protein Binding; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; Structure-Activity Relationship; Tubercidin

2009
9-(trans-2',trans-3'-dihydroxycyclopent-4'-enyl) derivatives of adenine and 3-deazaadenine: potent inhibitors of bovine liver S-adenosylhomocysteine hydrolase.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:3

    Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosylhomocysteinase; Animals; Cattle; Hydrolases; Kinetics; Liver; NAD

1988
Alterations in nucleotide pools induced by 3-deazaadenosine and related compounds. Role of adenylate deaminase.
    Biochemical pharmacology, 1988, Apr-01, Volume: 37, Issue:7

    Topics: Adenine; Adenosine Kinase; Alanine; Aminoglycosides; AMP Deaminase; Animals; Anti-Bacterial Agents; Cell Survival; Coformycin; Hypoxanthine; Hypoxanthines; Mice; Nucleotide Deaminases; Nucleotides; Time Factors; Tubercidin

1988
Thermodynamic stability and drug-binding properties of oligodeoxyribonucleotide duplexes containing 3-deazaadenine:thymine base pairs.
    Nucleic acids research, 1993, Apr-25, Volume: 21, Issue:8

    Topics: Adenine; Base Composition; Base Sequence; Molecular Sequence Data; Molecular Structure; Oligodeoxyribonucleotides; Thermodynamics; Thymine

1993
Minor groove functional groups are critical for the B-form conformation of duplex DNA.
    Biochemistry, 2001, Jan-30, Volume: 40, Issue:4

    Topics: Adenine; Circular Dichroism; DNA; Humidity; Nucleic Acid Conformation; Nucleic Acid Denaturation; Nucleic Acid Heteroduplexes; Oligonucleotides; Poly dA-dT; Pyridones; Salts; Sodium Chloride; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Thermodynamics; Thionucleotides; Trifluoroethanol

2001
Design and synthesis of a series of chlorinated 3-deazaadenine analogues.
    Nucleosides, nucleotides & nucleic acids, 2003, Volume: 22, Issue:12

    Topics: Adenine; Antineoplastic Agents; Chlorine; Drug Design; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Purines

2003
Direct comparison of A- and T-strand minor groove interactions in DNA curvature at A tracts.
    Biochemistry, 2004, Feb-03, Volume: 43, Issue:4

    Topics: Adenine; Base Composition; Base Pairing; Binding Sites; Cations; DNA; Hydrogen Bonding; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Static Electricity; Thionucleotides; Thymine

2004
Folate deficiency and homocysteine induce toxicity in cultured dorsal root ganglion neurons via cytosolic calcium accumulation.
    Aging cell, 2004, Volume: 3, Issue:2

    Topics: Adenine; Aniline Compounds; Animals; Calcium; Cells, Cultured; Chick Embryo; Cytosol; Dizocilpine Maleate; Folic Acid; Folic Acid Deficiency; Ganglia, Spinal; Homocysteine; Membrane Potentials; Microscopy, Fluorescence; Mitochondria; Neurons; Nimodipine; Oxidative Stress; Reactive Oxygen Species; Thapsigargin; Xanthenes

2004
Synthesis of a dA-dT base pair analogue and its effects on DNA-ligand binding.
    Bioorganic chemistry, 2001, Volume: 29, Issue:4

    Topics: Adenine; Base Pairing; Base Sequence; Bisbenzimidazole; DNA; Hydrogen Bonding; Indoles; Molecular Structure; Nucleic Acid Conformation; Nucleosides; Poly dA-dT; Pyridones

2001
Synthesis of 3-deaza-3-nitro-2'-deoxyadenosine.
    Bioorganic & medicinal chemistry, 2006, Mar-15, Volume: 14, Issue:6

    Topics: Adenine; Deoxyadenosines; Glycosylation; Molecular Structure

2006
Structure and function of eritadenine and its 3-deaza analogues: potent inhibitors of S-adenosylhomocysteine hydrolase and hypocholesterolemic agents.
    Biochemical pharmacology, 2007, Apr-01, Volume: 73, Issue:7

    Topics: Adenine; Adenosylhomocysteinase; Animals; Anticholesteremic Agents; Rats; S-Adenosylhomocysteine; Substrate Specificity

2007
Thermodynamic characterization of DNA with 3-deazaadenine and 3-methyl-3-deazaadenine substitutions: the effect of placing a hydrophobic group in the minor groove of DNA.
    The journal of physical chemistry. B, 2010, Jun-10, Volume: 114, Issue:22

    Topics: Adenine; Base Sequence; DNA; Molecular Structure; Nucleic Acid Conformation; Thermodynamics; Water

2010
Influence of the nucleobase and anchimeric assistance of the carboxyl acid groups in the hydrolysis of amino acid nucleoside phosphoramidates.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2012, Jan-16, Volume: 18, Issue:3

    Topics: Adenine; Amides; Amino Acids; Antiviral Agents; Crystallography, X-Ray; HIV-1; Kinetics; Magnetic Resonance Spectroscopy; Models, Theoretical; Molecular Conformation; Nucleosides; Phosphoric Acids; Prodrugs; Structure-Activity Relationship

2012
C-3 halo and 3-methyl substituted 5'-nor-3-deazaaristeromycins: synthesis and antiviral properties.
    Bioorganic & medicinal chemistry, 2013, Jan-01, Volume: 21, Issue:1

    Topics: Adenine; Adenosine; Antiviral Agents; Crystallography, X-Ray; Humans; Models, Molecular; Virus Diseases; Viruses

2013
Structure-Activity Relationships of Neplanocin A Analogues as S-Adenosylhomocysteine Hydrolase Inhibitors and Their Antiviral and Antitumor Activities.
    Journal of medicinal chemistry, 2015, Jun-25, Volume: 58, Issue:12

    Topics: Adenine; Adenosine; Adenosylhomocysteinase; Animals; Antineoplastic Agents; Antiviral Agents; Cell Line, Tumor; Chlorocebus aethiops; Enzyme Inhibitors; Humans; Molecular Docking Simulation; Neoplasms; Structure-Activity Relationship; Vero Cells; Virus Diseases; Viruses

2015
Enantiomeric 3-deaza-1',6'-isoneplanocin and its 3-bromo analogue: Synthesis by the Ullmann reaction and their antiviral properties.
    Bioorganic & medicinal chemistry letters, 2016, Feb-01, Volume: 26, Issue:3

    Topics: Adenine; Adenosine; Adenosylhomocysteinase; Antiviral Agents; Cytomegalovirus; Ebolavirus; Humans; Morbillivirus; Norovirus; Nucleosides; Stereoisomerism

2016