adenine has been researched along with 2-fluoroadenine in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (22.73) | 18.7374 |
| 1990's | 1 (4.55) | 18.2507 |
| 2000's | 10 (45.45) | 29.6817 |
| 2010's | 6 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Koning, HP; Eze, AA; Gustavsson, AL; Hammarström, LG; Lundbäck, T; Olivera, GC; Rottenberg, ME; Sjöberg, B; Svensson, R; Vodnala, SK; Yeheskieli, E | 1 |
| Carlson, EE; Goswami, M; Wilke, KE | 1 |
| Nygaard, P; Saxild, HH | 1 |
| Huang, P; Plunkett, W | 1 |
| Jackson, D; McInerney, D; Miller, BE; Miller, FR | 1 |
| Avramis, VI; Plunkett, W | 1 |
| Allan, PW; Bennett, LL; Gillespie, GY; Parker, WB; Rose, LM; Shaddix, SC; Speegle, HF | 1 |
| Bennetts, E; Both, GW; Madden, V; Martiniello-Wilks, R; Russell, PJ; Smith, K; Voeks, D | 1 |
| BROCKMAN, RW; CHAMBERS, P; MONCRIEF, C; PITTILLO, RF | 1 |
| Ito, Y; Kim, HS; Kitade, Y; Kojima, H; Nakanishi, M; Ueno, Y; Wataya, Y; Yabe, S; Yamagiwa, D; Zulfiqur, F | 1 |
| Deng, WP; Kirk, KL; Rezende, MM; Ye, S | 1 |
| Both, GW; Cameron, F; Cooke-Yarborough, C; Coulston, N; Ho, T; Lockett, TJ; Martiniello-Wilks, R; Moghaddam, M; Molloy, PL; Russell, PJ; Shaw, JM; Smith, IK; Wang, XY; Webster, LK | 1 |
| Geierstanger, BH; Hennig, M; Scott, LG; Williamson, JR | 1 |
| Ealick, SE; Wang, CC; Wang, WH; Wu, SW; Zang, Y | 1 |
| Allan, PW; Fowler, AT; Hassan, AE; Parker, WB; Secrist, JA; Silamkoti, AV; Sorscher, EJ | 1 |
| Bauta, WE; Cantrell, WR; Schulmeier, BE | 1 |
| Charlot, F; Choinard, S; Nogué, F; Schaefer, DG; Trouiller, B | 1 |
| Afshar, S; Morrison, SL; Sawaya, MR | 1 |
| Guillen, KP; Harrison, RG; Kurkjian, C; Restuccia, A | 1 |
| Charlot, F; Collonnier, C; Epert, A; Guyon-Debast, A; Maclot, F; Mara, K; Nogué, F; Schaefer, DG; White, C | 1 |
| Bald, I; Dąbkowska, I; Ebel, K; Kopyra, J; Milosavljević, AR; Rackwitz, J; Ranković, MLj | 1 |
| Behbahani, TE; Parker, WB; Rosenthal, EL; Sorscher, EJ | 1 |
1 review(s) available for adenine and 2-fluoroadenine
| Article | Year |
|---|---|
Intratumoral generation of 2-fluoroadenine to treat solid malignancies of the head and neck.
Topics: Adenine; Escherichia coli; Head and Neck Neoplasms; Humans; Purine-Nucleoside Phosphorylase; Squamous Cell Carcinoma of Head and Neck; Transduction, Genetic | 2019 |
21 other study(ies) available for adenine and 2-fluoroadenine
| Article | Year |
|---|---|
Structure-activity relationships of synthetic cordycepin analogues as experimental therapeutics for African trypanosomiasis.
Topics: Animals; Cell Survival; Cells, Cultured; Deoxyadenosines; Dose-Response Relationship, Drug; Humans; Male; Mice; Mice, Inbred C57BL; Models, Molecular; Molecular Structure; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense; Trypanosomiasis, African | 2013 |
Rational Design of Selective Adenine-Based Scaffolds for Inactivation of Bacterial Histidine Kinases.
Topics: Adenine; Adenosine Triphosphate; Anti-Bacterial Agents; Aspartic Acid; Bacteria; Drug Design; Histidine Kinase; HSP90 Heat-Shock Proteins; Models, Molecular; Molecular Docking Simulation; Structure-Activity Relationship | 2017 |
Genetic and physiological characterization of Bacillus subtilis mutants resistant to purine analogs.
Topics: Adenine; Adenine Phosphoribosyltransferase; Azaguanine; Bacillus subtilis; Biological Transport; Chromosome Mapping; Drug Resistance, Microbial; Genes, Bacterial; Genotype; Pentosyltransferases; Purines; Xanthines | 1987 |
Phosphorolytic cleavage of 2-fluoroadenine from 9-beta-D-arabinofuranosyl-2-fluoroadenine by Escherichia coli. A pathway for 2-fluoro-ATP production.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Binding, Competitive; Cell Line; Escherichia coli; Humans; Kidney; Kinetics; Leukemia; Liver; Mice; Phosphates; Purine Nucleosides; Rats; Vidarabine | 1987 |
Metabolic cooperation between mouse mammary tumor subpopulations in three-dimensional collagen gel cultures.
Topics: Adenine; Animals; Cell Communication; Cell Line; Cells, Cultured; Collagen; Culture Media; Drug Resistance; Extracellular Matrix; Female; Gels; Mammary Neoplasms, Experimental; Mice; Ouabain; Thioguanine | 1986 |
2-fluoro-ATP: a toxic metabolite of 9-beta-D-arabinosyl-2-fluoroadenine.
Topics: Adenine; Adenosine Triphosphate; Animals; Arabinonucleotides; Cell Line; Chromatography, High Pressure Liquid; Leukemia P388; Leukemia, Experimental; Mice; Vidarabine | 1983 |
Metabolism and metabolic actions of 6-methylpurine and 2-fluoroadenine in human cells.
Topics: 3T3 Cells; Adenine; Animals; Cell Division; Cell Line; Cycloheximide; DNA; Fluorouracil; Humans; Mice; Nucleic Acid Synthesis Inhibitors; Protein Synthesis Inhibitors; Purines; RNA | 1998 |
Gene therapy for prostate cancer delivered by ovine adenovirus and mediated by purine nucleoside phosphorylase and fludarabine in mouse models.
Topics: Adenine; Animals; Avian Sarcoma Viruses; Gene Expression; Genetic Therapy; Genetic Vectors; Humans; Male; Mastadenovirus; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasms, Experimental; Prodrugs; Prostatic Neoplasms; Purine-Nucleoside Phosphorylase; Transduction, Genetic; Transplantation, Heterologous; Tumor Cells, Cultured; Vidarabine Phosphate | 2002 |
ANTIMICROBIAL ACTIVITY OF 2-FLUOROADENOSINE AND 2-FLUOROADENINE.
Topics: Adenine; Adenosine; Anti-Infective Agents; Bacteria; Nucleosides; Pharmacology; Research | 1964 |
Synthesis of carbocyclic and acyclic nucleosides possessing 2-fluoroadenine derivatives and their inhibitory activities against Plasmodium falciparum SAH hydrolase.
Topics: Adenine; Adenosylhomocysteinase; Animals; Antimalarials; Enzyme Inhibitors; Hydrolases; Nucleosides; Plasmodium falciparum; Recombinant Proteins | 2003 |
Convenient synthesis of 2'-deoxy-2-fluoroadenosine from 2-fluoroadenine.
Topics: Adenine; Deoxyadenosines; Molecular Structure | 2003 |
Preclinical evaluation of a prostate-targeted gene-directed enzyme prodrug therapy delivered by ovine atadenovirus.
Topics: Adenine; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; DNA Replication; Drug Evaluation, Preclinical; Genetic Therapy; Genetic Vectors; Humans; Male; Mice; Mice, Nude; Neoplasm Transplantation; Prodrugs; Prostatic Neoplasms; Purine-Nucleoside Phosphorylase; Vidarabine Phosphate | 2004 |
Enzymatic synthesis and 19F NMR studies of 2-fluoroadenine-substituted RNA.
Topics: Adenine; Adenosine Triphosphate; Adenylate Kinase; Creatine Kinase; Fluorine; HIV Long Terminal Repeat; HIV-2; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; RNA, Viral; Thermodynamics | 2004 |
Identification of a subversive substrate of Trichomonas vaginalis purine nucleoside phosphorylase and the crystal structure of the enzyme-substrate complex.
Topics: Adenine; Adenosine; Animals; Binding Sites; Catalysis; Crystallography, X-Ray; Dose-Response Relationship, Drug; Electrons; Formycins; Humans; Hydrolysis; Inhibitory Concentration 50; Inosine; Ligands; Models, Chemical; Models, Molecular; Protein Binding; Protein Conformation; Purine-Nucleoside Phosphorylase; Recombinant Proteins; Substrate Specificity; Threonine; Time Factors; Trichomonas vaginalis; X-Rays | 2005 |
Synthesis and biological activity of 2-fluoro adenine and 6-methyl purine nucleoside analogs as prodrugs for suicide gene therapy of cancer.
Topics: Adenine; Antineoplastic Agents; Carbon; Escherichia coli; Genetic Therapy; Humans; Models, Chemical; Mutation; Neoplasms; Nucleosides; Prodrugs; Purine Nucleosides; Purine-Nucleoside Phosphorylase; Purines; Substrate Specificity; Xylose | 2005 |
Preparation of a fludarabine intermediate via selective alkylation of 2-fluoroadenine.
Topics: Adenine; Alkylation; Arabinose; Nucleic Acid Conformation; Pentanols; Stereoisomerism; Vidarabine | 2006 |
Comparison of gene targeting efficiencies in two mosses suggests that it is a conserved feature of Bryophyte transformation.
Topics: Adenine; Adenine Phosphoribosyltransferase; Bryophyta; Gene Targeting; Models, Genetic; Mutation; Plant Proteins; Plants, Genetically Modified; Protoplasts; Species Specificity; Transformation, Genetic | 2007 |
Structure of a mutant human purine nucleoside phosphorylase with the prodrug, 2-fluoro-2'-deoxyadenosine and the cytotoxic drug, 2-fluoroadenine.
Topics: Adenine; Antineoplastic Agents; Biocatalysis; Crystallography, X-Ray; Deoxyadenosines; Genetic Engineering; Humans; Models, Molecular; Mutation; Prodrugs; Protein Binding; Protein Conformation; Purine-Nucleoside Phosphorylase; Substrate Specificity | 2009 |
Annexin V-Directed Enzyme Prodrug Therapy Plus Docetaxel for the Targeted Treatment of Pancreatic Cancer.
Topics: Adenine; Adenocarcinoma; Annexin A5; Antineoplastic Combined Chemotherapy Protocols; Carbon-Sulfur Lyases; Cell Death; Cell Line, Tumor; Cytosine Deaminase; Docetaxel; Dose-Response Relationship, Drug; Enzymes; Flucytosine; Fluorouracil; Humans; Methanol; Molecular Targeted Therapy; Organoselenium Compounds; Pancreatic Neoplasms; Prodrugs; Purine-Nucleoside Phosphorylase; Recombinant Fusion Proteins; Selenomethionine; Taxoids; Tubulin Modulators; Vidarabine | 2015 |
CRISPR-Cas9-mediated efficient directed mutagenesis and RAD51-dependent and RAD51-independent gene targeting in the moss Physcomitrella patens.
Topics: Adenine; Arabidopsis Proteins; Bryopsida; Clustered Regularly Interspaced Short Palindromic Repeats; CRISPR-Cas Systems; DNA End-Joining Repair; Endonucleases; Gene Targeting; Genetic Engineering; Genome, Plant; Homologous Recombination; Mutagenesis; Plants, Genetically Modified; Protoplasts; Rad51 Recombinase; Sequence Deletion; Sequence Homology; Streptococcus pyogenes; Transformation, Genetic | 2017 |
Sensitizing DNA Towards Low-Energy Electrons with 2-Fluoroadenine.
Topics: Adenine; DNA; Electrons; Quantum Theory | 2016 |