adenine has been researched along with 2-aminopurine in 195 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 94 (48.21) | 18.7374 |
| 1990's | 33 (16.92) | 18.2507 |
| 2000's | 38 (19.49) | 29.6817 |
| 2010's | 27 (13.85) | 24.3611 |
| 2020's | 3 (1.54) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, ST; Choong, KF; Hsieh, JF; Wu, SH; Yang, YL | 1 |
| Carlson, EE; Goswami, M; Wilke, KE | 1 |
| Goodman, MF; Gore, WC; Hopkins, R | 1 |
| Kimball, RF; Perdue, SW | 1 |
| Kocharian, ShM | 1 |
| Janion, C | 1 |
| Chukanova, TI; Kocharian, ShM; Sukhodolets, VV | 1 |
| Glickman, B; Radman, M; van den Elsen, P | 1 |
| Wallis, C; Wilkie, D | 1 |
| Bessman, MJ; Engler, MJ | 1 |
| Aleksandrushkina, NI; Khudiakov, IIa; Kirnos, MD; Vaniushin, BF | 1 |
| Branscomb, EW; Clayton, LK; Galas, DJ; Goodman, MF | 1 |
| Mollica, F; Nuciforo, G; Pavone, L; Sorge, G | 1 |
| Duncan, ME | 1 |
| Alexandrushkina, NI; Khudyakov, IY; Kirnos, MD; Vanyushin, BF | 1 |
| Rudakov, VF | 1 |
| Bierzynski, A; Kozlowska, H; Wierzchowski, KL | 1 |
| Bierzyński, A; Kozlowska, H; Wierzchowski, KI | 1 |
| Bierzyński, A; Kollowska, H; Proba, Z; Wierzchowski, KL | 1 |
| Rapoport, H; Wegner, MM | 1 |
| Bernstein, C; Gensler, HL; Holmes, GE; Morgan, D; Schneider, S | 1 |
| Halevy, C; Rahat, A; Ronen, A | 1 |
| LeBreton, PR; Padva, A; Peng, S | 1 |
| Beburov, MIu; Stepanov, AI; Zhdanov, VG | 1 |
| Bishop, PL; Cooper, GE; DiMartino, DL; Khattar, NH; Turker, MS | 1 |
| Bayat-Sarmadi, M; Houdebine, LM; Maliénou-Ngassa, R; Puissant, C | 1 |
| Huang, JT; Schneider, RJ | 1 |
| Clegg, RM; Diekmann, S; Loontiens, FG; McLaughlin, LW | 1 |
| Belinsky, GS; Harris, MO; Schlegel, R | 1 |
| Belinsky, GS; Lee, D; Schlegel, R; Steinmann, KE | 1 |
| Brockman, HE; de Serres, FJ; Overton, LK | 1 |
| Brockman, HE; de Serres, FJ | 1 |
| Heath, JK; Hirst, EA; Mahadevan, LC; Rathjen, PD; Wills, AJ | 1 |
| Chovnick, A; Dutton, FL | 1 |
| Garkov, S; Haupter, S; Köberle, B; Speit, G | 1 |
| Akiyama, Y; Hashimoto, H; Kitoh, T; Kubota, M; Mikawa, H; Shimizu, T; Takimoto, T | 1 |
| Avery, TL; Finch, RA; Hanna, NB; Imamura, N; Larson, SB; Lewis, AF; Revankar, GR; Robins, RK | 1 |
| Brody, MS; Samuel, CE | 1 |
| Simili, M; Tartaglia, P; Turchi, G | 1 |
| Jhaveri, S; Laurence, J; Salmon, JE; Sikder, SK | 1 |
| Shah, YB; Wigler, PW | 1 |
| Kumar, R; Kusari, J; Sen, GC; Tiwari, RK | 1 |
| Diver, WP; Woodcock, DM | 1 |
| Clauss, IM; Huez, GA; Paillard, FC; Wathelet, MG | 1 |
| Brockman, HE; de Serres, FJ; Hung, CY; Ong, T | 1 |
| Greene, LA; Loeb, DM; Rukenstein, A; Volonté, C | 1 |
| Boyd, MR; Harnden, MR; Jarvest, RL; Sutton, D; Vere Hodge, RA | 2 |
| Chen, FM; Eritja, R; Fazakerley, GV; Goodman, MF; Kaplan, BE; Khwaja, T; Sowers, LC | 1 |
| Bandyopadhyay, R; Das, J; Sengupta, A | 1 |
| Heath, JK; Mahadevan, LC; Targett, K | 1 |
| Matveyev, AV; Szekeres, M | 1 |
| Claesens, F; Gräslund, A; Larsson, U; Lycksell, PO; McLaughlin, LW; Rigler, R | 1 |
| Chollet, A; Kawashima, E | 1 |
| Holt, G; Rogers, ME; Rogers, SD; Saunders, G | 1 |
| Czochralska, B; Johansson, NG; Kusmierek, JT; Shugar, D | 1 |
| Belogurov, AA; Del'ver, EP; Efimova, EP; Zavil'gel'skiĭ, GB | 1 |
| Benseler, F; Leong, T; McLaughlin, LW; Piel, N | 1 |
| Brockman, HE; de Serres, FJ; Hung, CY; Ong, TM | 1 |
| Belogurov, AA; Delver, EP; Efimova, EP | 1 |
| Hofnung, M; Quillardet, P | 1 |
| Amsterdam, A; Grafstrom, RH; Zachariasewycz, K | 1 |
| Brockman, HE; de Serres, FJ; Hung, CY; Overton, LK | 1 |
| Bodalbhai, L; Brajter-Toth, A | 1 |
| Coll, M; Rich, A; van Boom, JH; van der Marel, GA; Wang, AH | 1 |
| Keller, A; Maniatis, T; Whittemore, LA; Zinn, K | 1 |
| Cheong, C; Chollet, A; Tinoco, I | 1 |
| Marcus, PI; Sekellick, MJ | 1 |
| Eritja, R; Fazakerley, GV; Goodman, MF; Kaplan, BE; Sowers, LC | 2 |
| Zgaga, Z | 1 |
| Eritja, R; Goodman, MF; Kaplan, BE; Mhaskar, D; Petruska, J; Sowers, LC | 1 |
| Martin, GM; Turker, MS | 1 |
| Glickman, BW | 1 |
| Goodman, MF; Hopkins, RL | 2 |
| Aida, M; Nagata, C; Yamane, K | 1 |
| Goodman, MF; Hopkins, RL; Lasken, R; Mhaskar, DN | 1 |
| Adamson, DJ; Bennett, LL; Brockman, RW; Rose, LM; Smithers, D | 1 |
| Clifford, AJ; Clifford, CK; Ho, YK; Koehn, DJ; Sobieski, RJ | 1 |
| Caillet-Fauquet, P; Maenhaut-Michel, G | 2 |
| Clough, W; Grossberger, D | 1 |
| Grigg, GW; MacPhee, DG; Podger, DM | 1 |
| Bebenek, K; Janion, C | 1 |
| Bessman, MJ; Pless, RC | 1 |
| MacPhee, DG; Nagel, BA; Podger, DM | 1 |
| Arraj, JA; Craig, RJ; Marinus, MG | 1 |
| Goodman, MF; Mhaskar, DN | 1 |
| Howard, FB; Miles, HT | 1 |
| Goodman, MF; Ratliff, RL | 1 |
| Bradley, WE; Simon, AE; Taylor, MW | 1 |
| Chen, CW; Cohen, JS; Howard, FB; Miles, HT | 1 |
| Garber, BB; Gots, JS | 1 |
| Goodman, MF; Watanabe, SM | 2 |
| Barrett, JC | 1 |
| Caras, IW; Coffino, P; MacInnes, MA; Martin, DW; Persing, DH | 1 |
| Ronen, A | 1 |
| Warren, RA | 1 |
| Ong, TM; Simpson, JP; Sorenson, WG | 1 |
| Adams, CW; Fowler, RG; McGinty, L; Persing, DH | 1 |
| Bessman, MJ; Levitt, LM; Pless, RC | 1 |
| Ripley, LS | 1 |
| Bailly, C; Waring, MJ | 2 |
| Jennings, CD; Khattar, NH; Turker, MS; Walker, KA | 1 |
| Efremova, EJ; Limborska, SA; Myasnikov, VA; Potapov, VK; Prosnyak, MI; Sverdlov, ED; Veselovskaya, SI | 1 |
| Carnero, A; Jiménez, B; Lacal, JC | 1 |
| Acedo, M; Aviño, A; Eritja, R; Fàbrega, C; Fagan, P; Goodman, M; Wemmer, D | 1 |
| Adamiak, RW; Zagórowska, I | 1 |
| Allan, BW; Reich, NO | 1 |
| Dubois, S; Eritja, R; Guschlbauer, W; Thielking, V | 1 |
| Bailly, C; Mollegaard, NE; Nielsen, PE; Waring, MJ | 1 |
| Allemann, RK; Meierhans, D; Sieber, M | 1 |
| Christensen, L; Dahl, O; Haaima, G; Hansen, HF; Nielsen, PE | 1 |
| Wong, ML; Yen, YR | 1 |
| Buc, H; Lavigne, M | 1 |
| Barton, JK; Kelley, SO | 1 |
| Evdokimov, AA; Hattman, S; Jen-Jacobson, L; Kossykh, VG; Malygin, EG; Petrov, NA; Zinoviev, VV | 1 |
| Freiman, JS; McCaughan, GW | 1 |
| Mishra, PC; Mishra, SK; Shukla, MK | 1 |
| Leung, N | 1 |
| Gowher, H; Jeltsch, A | 1 |
| Barton, JK; Fiebig, T; Schiemann, O; Wan, C; Zewail, AH | 1 |
| Grande Santamaría, L; Romero Gómez, M; Suárez García, E | 1 |
| Kontogiannis, L; Lilley, DM; Maxwell, K; Wilson, TJ; Zhao, ZY | 1 |
| Lau, GK | 1 |
| Delaney, WE; Locarnini, S; Shaw, T | 1 |
| Berger, MD; Jackson, BE; Lee, AM; Roca, AI; Simonette, RA; Singleton, SF | 1 |
| Kozlov, IA; Orgel, LE | 1 |
| de Man, RA; Niesters, HG; Wolters, LM | 1 |
| Perrillo, RP | 1 |
| Chaput, JC; Sinha, S; Switzer, C | 1 |
| Terrault, NA | 1 |
| Lafontaine, DA; Lilley, DM; Wilson, TJ; Zhao, ZY | 1 |
| Cairns, MJ; King, A; Sun, LQ | 1 |
| Holý, A; Kmoníèková, E; Potmesil, P; Zídek, Z | 1 |
| DUNCAN, RE; SETTERFIELD, G | 1 |
| REMY, CN | 1 |
| HAMZI, HQ; SKOOG, F | 1 |
| BERENBLUM, I; KAYE, AM; TRAININ, N | 1 |
| DYER, E; FARRIS, RE; REITZ, JM | 1 |
| HOWARD, BD; TESSMAN, I | 1 |
| GUTHRIE, R; LU, WC | 1 |
| Lagget, M; Rizzetto, M | 1 |
| Doláková, P; Holý, A; Masojídková, M | 1 |
| MORGAN, HR | 1 |
| Avci, A; Erhardt, A; Häussinger, D; Heintges, T; Lörke, J; Sagir, A | 1 |
| Andrei, G; De Clercq, E; Snoeck, R | 1 |
| Breaker, RR; Cheah, MT; Crothers, DM; Wickiser, JK | 1 |
| O'Neil, LL; Wiest, O | 1 |
| Holý, A; Kmonícková, E; Potmesil, P; Zídek, Z | 1 |
| Barbieri, CM; Kaul, M; Pilch, DS | 1 |
| Jean, JM; Krueger, BP | 1 |
| Batey, RT; Gilbert, SD; Stoddard, CD; Wise, SJ | 1 |
| Borin, AC; Merchán, M; Serrano-Andrés, L | 1 |
| Arndt-Jovin, DJ; Jovin, TM; Kaluzhny, DN; Shchyolkina, AK; Zhurkin, VB | 1 |
| Lafontaine, DA; Lemay, JF; Lilley, DM; Penedo, JC; Tremblay, R | 1 |
| Lafontaine, DA; Lemay, JF | 1 |
| Barbieri, CM; LaVoie, EJ; Pilch, DS; Rice, JE; Rzuczek, SG; Srinivasan, AR | 1 |
| Barch, M; Breslauer, KJ; Castner, EW; Lee, BJ; Völker, J | 1 |
| Augustyn, KE; Barton, JK; Davis, ML; Genereux, JC; Shao, F | 1 |
| Matsika, S; Mburu, E | 1 |
| Kuchta, RD; Patro, JN; Urban, M | 1 |
| Xia, T; Zhao, L | 1 |
| Kawai, K; Kodera, H; Majima, T | 1 |
| Chaires, JB; Garbett, NC; Petraccone, L; Trent, JO | 1 |
| Jain, N; Liu, JD; Xia, T; Zhao, L | 1 |
| Fernández-Botello, A; Holy, A; Moreno, V; Operschall, BP; Sigel, H | 1 |
| Buma, WJ; Drabbels, M; Rijs, AM; Smolarek, S | 1 |
| Degtyareva, NN; Petty, JT | 1 |
| Leutwyler, S; Lobsiger, S; Sinha, RK; Trachsel, M | 1 |
| Balzarini, J; Baszczyňski, O; de Clercq, E; Dračínský, M; Holý, A; Janeba, Z; Jansa, P; Klepetářová, B; Votruba, I | 1 |
| Castiñeiras, A; Choquesillo-Lazarte, D; Domínguez-Martín, A; González-Pérez, JM; Niclós-Gutiérrez, J | 1 |
| Ghatak, C; Mandal, S; Pramanik, R; Rao, VG; Sarkar, N; Sarkar, S; Verma, PK | 1 |
| Fu, Q; Fuhrmann, A; Getfert, S; Lindsay, S; Reimann, P; Ros, R | 1 |
| Blindauer, CA; Gómez-Coca, RB; Holý, A; Operschall, BP; Sigel, A; Sigel, H | 1 |
| Liang, J; Matsika, S; Nguyen, QL | 1 |
| Burrows, CJ; Ding, Y; Fleming, AM; Jin, Q; White, HS | 1 |
| Golinelli-Pimpaneau, B; Guelorget, A; Guérineau, V; Hamdane, D | 1 |
| Belogurov, GA; Malinen, AM; Turtola, M | 1 |
| Castiñeiras, A; Choquesillo-Lazarte, D; Domínguez-Martín, A; El Bakkali, H; García-Rubiño, ME; González-Pérez, JM; Niclós-Gutiérrez, J; Nurchi, VM; Pérez-Toro, I; Vílchez-Rodríguez, E | 1 |
| Cialla-May, D; Pollok, S; Popp, J; Schwenkbier, L; Weber, K; Yüksel, S | 1 |
| Cameron, SA; Ducati, RG; Firestone, RS; Schramm, VL; Spitz, AZ; Tyler, PC | 1 |
| Hariharan, M; Kohler, B; Philip, AM; Remington, JM | 1 |
| Lagisetti, C; Park, J; Sambucetti, LC; Shi, Y; Webb, TR; Zhou, W | 1 |
| Mondal, S; Puranik, M | 1 |
| Du, Y; Li, T; Peng, P | 1 |
| Kamble, NR; Sigurdsson, ST | 1 |
| Hornum, M; Kumar, P; Nielsen, P; Nielsen, RB; Petersen, M; Sharma, PK; Stendevad, J | 1 |
| Charnay, AP; Kohl, FR; Kohler, B; Snyder, JA; Zhang, Y | 1 |
| Czernecki, D; Delarue, M; Kaminski, PA; Legrand, P; Rosario, S; Tekpinar, M | 1 |
| Green, NJ; Kruse, H; Rak, J; Spisz, P; Šponer, J; Stadlbauer, P; Szabla, R; Zdrowowicz, M | 1 |
| Datta, D; Egli, M; Madaoui, M; Manoharan, M; Ross, BS; Wassarman, K; Zlatev, I | 1 |
13 review(s) available for adenine and 2-aminopurine
| Article | Year |
|---|---|
Mutagenicity of 2-aminopurine, 6-N-hydroxylaminopurine, and 2-amino-N6-hydroxyadenine in Neurospora crassa.
Topics: 2-Aminopurine; Adenine; Alleles; Chemical Phenomena; Chemistry; Dose-Response Relationship, Drug; Genes, Fungal; Methylnitronitrosoguanidine; Mutagens; Mutation; Neurospora; Neurospora crassa | 1985 |
2-Aminopurine mutagenesis in Escherichia coli.
Topics: 2-Aminopurine; Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Base Composition; Deoxycytosine Nucleotides; DNA Polymerase I; DNA Repair; DNA, Bacterial; Escherichia coli; Hydrogen Bonding; Insecta; Mutagens; Mutation; Plants; Saccharomyces cerevisiae | 1985 |
2-Aminopurine.
Topics: 2-Aminopurine; Adenine; Animals; Bacteria; Bacteriophages; DNA; DNA Replication; Fungi; Genetic Code; Insecta; Mammals; Mutagens; Mutation; Plants; RNA; Temperature; Transcription, Genetic | 1980 |
Modified bases in bacteriophage DNAs.
Topics: 2-Aminopurine; 5-Methylcytosine; Adenine; Bacteriophages; Base Composition; Chemical Phenomena; Chemistry; Chemistry, Physical; Cytosine; Deoxyribonucleases; DNA Replication; DNA, Viral; Nucleic Acid Conformation; Pentoxyl; Substrate Specificity; Templates, Genetic; Thymine; Transcription, Genetic; Uracil | 1980 |
Current limitations to nucleoside analogue therapy for chronic hepatitis B virus infection in the liver transplant and non-transplant settings.
Topics: 2-Aminopurine; Adenine; Antiviral Agents; DNA, Viral; Famciclovir; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Transplantation; Organophosphonates; Treatment Outcome | 2000 |
Nucleoside analogues in the treatment of chronic hepatitis B.
Topics: 2-Aminopurine; Adenine; Antiviral Agents; Deoxycytidine; Emtricitabine; Famciclovir; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates | 2000 |
Hepatitis B infection in China.
Topics: 2-Aminopurine; Adenine; Antiviral Agents; China; Deoxycytidine; DNA, Viral; Drug Therapy, Combination; Drugs, Chinese Herbal; Emtricitabine; Famciclovir; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Organophosphonates; Thymosin | 2001 |
Resistance of hepatitis B virus to antiviral drugs: current aspects and directions for future investigation.
Topics: 2-Aminopurine; Adenine; Amino Acid Sequence; Animals; Anti-HIV Agents; Antimetabolites; Antiviral Agents; Biological Availability; Cell Line; Clinical Trials as Topic; DNA Replication; DNA-Directed DNA Polymerase; DNA, Viral; Drug Design; Drug Evaluation, Preclinical; Drug Resistance, Multiple; Drug Resistance, Viral; Drug Therapy, Combination; Enzyme Inhibitors; Famciclovir; Gene Products, pol; Hepatitis B; Hepatitis B virus; Hepatitis Viruses; Hepatitis, Animal; HIV; Humans; Lamivudine; Models, Animal; Molecular Sequence Data; Molecular Structure; Nucleosides; Organophosphonates; Sequence Alignment; Sequence Homology, Amino Acid; Species Specificity; Virus Replication | 2001 |
Nucleoside analogues for chronic hepatitis B.
Topics: 2-Aminopurine; Adenine; Antiviral Agents; Famciclovir; Ganciclovir; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates; Reverse Transcriptase Inhibitors | 2001 |
How will we use the new antiviral agents for hepatitis B?
Topics: 2-Aminopurine; Adenine; Alanine Transaminase; Antiviral Agents; Drug Resistance; Drug Therapy, Combination; Famciclovir; Ganciclovir; Gene Products, pol; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Mutation; Organophosphonates; Practice Guidelines as Topic | 2002 |
Current pharmacotherapy for the treatment of chronic hepatitis B.
Topics: 2-Aminopurine; Adenine; Antiviral Agents; Clinical Trials as Topic; Famciclovir; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferons; Lamivudine; Liver Transplantation; Mutation; Nucleosides; Organophosphonates | 2003 |
[New approaches in the treatment of hepatitis B].
Topics: 2-Aminopurine; Adenine; Antiviral Agents; Arabinofuranosyluracil; Carcinoma, Hepatocellular; Contraindications; Deoxycytidine; Emtricitabine; Famciclovir; Guanine; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Liver Neoplasms; Organophosphonates; Organophosphorus Compounds; Polyethylene Glycols; Prodrugs; Prognosis; Recombinant Proteins; Tenofovir; Zalcitabine | 2004 |
Probing RNA conformational dynamics and heterogeneity using femtosecond time-resolved fluorescence spectroscopy.
Topics: 2-Aminopurine; Adenine; Anisotropy; Equipment Design; Guanine; Models, Molecular; Models, Statistical; Molecular Conformation; Molecular Structure; Nucleic Acid Conformation; RNA; RNA, Viral; Spectrometry, Fluorescence; Time Factors | 2009 |
182 other study(ies) available for adenine and 2-aminopurine
| Article | Year |
|---|---|
The screening and characterization of 6-aminopurine-based xanthine oxidase inhibitors.
Topics: Allopurinol; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; Enzyme Inhibitors; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Plant Leaves; Purines; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Triticum; Xanthine Oxidase | 2007 |
Rational Design of Selective Adenine-Based Scaffolds for Inactivation of Bacterial Histidine Kinases.
Topics: Adenine; Adenosine Triphosphate; Anti-Bacterial Agents; Aspartic Acid; Bacteria; Drug Design; Histidine Kinase; HSP90 Heat-Shock Proteins; Models, Molecular; Molecular Docking Simulation; Structure-Activity Relationship | 2017 |
2-Aminopurine-induced mutagenesis in T4 bacteriophage: a model relating mutation frequency to 2-aminopurine incorporation in DNA.
Topics: 2-Aminopurine; Adenine; Aminopyrine; Coliphages; DNA, Viral; Models, Biological; Mutagens | 1977 |
Attempts to induce mutations in Haemophilus influenzae with the base analogues 5-bromodeoxyuridine and 2-aminopurine.
Topics: 2-Aminopurine; Adenine; Bromodeoxyuridine; DNA Repair; DNA Replication; DNA, Bacterial; Haemophilus influenzae; Mutagens; Mutation | 1977 |
[Genetic control of Escherichia coli K-12 strains' assimilation of 2,6-diaminopurine as a purine source].
Topics: 2-Aminopurine; Adenine; Adenine Phosphoribosyltransferase; Escherichia coli; Guanine; Hypoxanthines; Mutation; Transduction, Genetic | 1977 |
The efficiency and extent of mutagenic activity of some new mutagens of base-analogue type.
Topics: 2-Aminopurine; Adenine; Cytidine; DNA Repair; DNA, Bacterial; Escherichia coli; Genetic Techniques; Mutagens; Mutation; Salmonella typhimurium | 1978 |
[Mutations of resistance to 2,6-diaminopurine and 6-methylpurine that affect adenine phosphoribosyltransferase in Escherichia coli K-12].
Topics: 2-Aminopurine; Adenine; Adenine Phosphoribosyltransferase; Chromosome Mapping; Drug Resistance, Microbial; Escherichia coli; Mutation; Pentosyltransferases; Phenotype; Purines; Recombination, Genetic; Transduction, Genetic | 1977 |
Induced mutagenesis in dam- mutants of Escherichia coli: a role for 6-methyladenine residues in mutation avoidance.
Topics: 2-Aminopurine; Adenine; DNA Repair; DNA, Bacterial; Escherichia coli; Ethyl Methanesulfonate; Mutation; Ultraviolet Rays | 1978 |
Mitochondrial activity of 2,6-diaminopurine in Saccharomyces cerevisiae.
Topics: 2-Aminopurine; Adenine; Chloramphenicol; DNA, Mitochondrial; Drug Resistance, Microbial; Mutagens; Oligomycins; Phenotype; Saccharomyces cerevisiae | 1979 |
Characterization of a mutator DNA polymerase I from Salmonella typhimurium.
Topics: 2-Aminopurine; Adenine; DNA Polymerase I; DNA Replication; DNA-Directed DNA Polymerase; Mutation; Phenotype; Salmonella typhimurium; Substrate Specificity | 1979 |
[2,6-Diaminopurine--a new adenine substituent base in the DNA of cyanophage S-2].
Topics: 2-Aminopurine; Adenine; Chemical Phenomena; Chemistry; Chromatography; Cyanobacteria; DNA, Viral; Plant Viruses; Spectrum Analysis | 1977 |
Error induction and correction by mutant and wild type T4 DNA polymerases. Kinetic error discrimination mechanisms.
Topics: 2-Aminopurine; Adenine; Base Sequence; Coliphages; Deoxyribonucleotides; DNA Polymerase I; DNA Polymerase II; DNA-Directed DNA Polymerase; DNA, Viral; Exonucleases; Kinetics; Mutation; Species Specificity; Structure-Activity Relationship; Thermodynamics | 1979 |
A case of cyclopia. Role of environmental factors.
Topics: 2-Aminopurine; Abnormalities, Drug-Induced; Abnormalities, Severe Teratoid; Adenine; Anti-Bacterial Agents; Female; Humans; Maternal-Fetal Exchange; Pregnancy; Pregnancy Trimester, First; Virus Diseases | 1979 |
Isolation and preliminary characterization of drug resistant mutants of human lymphoblastoid cells.
Topics: 2-Aminopurine; Adenine; Adenine Phosphoribosyltransferase; Cell Line; Cell Membrane; Drug Resistance; Humans; Hypoxanthine Phosphoribosyltransferase; Karyotyping; Mutation; Nucleotidases; Ouabain; Thioguanine | 1977 |
Cyanophage S-2L contains DNA with 2,6-diaminopurine substituted for adenine.
Topics: 2-Aminopurine; Adenine; Bacteriophages; Centrifugation, Density Gradient; DNA, Viral; Nucleic Acid Conformation; Nucleic Acid Denaturation | 1978 |
[The antifolic activity of several derivatives of 2,4,6-triaminopyrimidine and 2,6-diaminopurine in a microbiologic test system].
Topics: 2-Aminopurine; Adenine; Biological Assay; Enterococcus faecalis; Folic Acid Antagonists; Pyrimidines | 1975 |
Investigations on purine and pyrimidine bases stacking associations in aqueous solutions by the fluorescence quenching method. I. Autoassociation of 2-aminopurine.
Topics: 2-Aminopurine; Adenine; Chemical Phenomena; Chemistry; Chemistry, Physical; Kinetics; Mathematics; Polymers; Spectrometry, Fluorescence; Thermodynamics | 1977 |
Investigations on purine and pyrimidine bases stacking associations in aqueous solutions by the fluorescence quenching method. II. Heteroassociation between 2-aminopurine and thymidine.
Topics: 2-Aminopurine; Adenine; Chemical Phenomena; Chemistry; Chemistry, Physical; Kinetics; Mathematics; Spectrometry, Fluorescence; Thermodynamics; Thymidine | 1977 |
Investigations on purine and pyrimidine bases stacking associations in aqueous solutions by the fluorescence quenching method. III. Intramolecular association of 9,9'-[1,3-propylene]-bis-2-aminopurine.
Topics: 2-Aminopurine; Adenine; Chemical Phenomena; Chemistry; Chemistry, Physical; Kinetics; Mathematics; Spectrometry, Fluorescence; Thermodynamics | 1977 |
Perhydrogenation of 2,8-diaminopurine.
Topics: 2-Aminopurine; Adenine; Catalysis; Chemical Phenomena; Chemistry; Hydrogenation; Methods; Saxitoxin | 1977 |
The dependence of HNO2 mutagenesis in phage T4 on ligase and the lack of dependence of 2AP mutagenesis on repair functions.
Topics: 2-Aminopurine; Adenine; Coliphages; DNA Repair; DNA, Viral; Gene Frequency; Hot Temperature; Ligases; Mutagens; Mutation; Nitrites; Nitrous Acid; Recombination, Genetic | 1976 |
Marker effects on reversion of T4rII mutants.
Topics: 2-Aminopurine; Adenine; Base Sequence; Bromouracil; Coliphages; DNA, Viral; Genes; Genetic Linkage; Mutation | 1976 |
Ultraviolet photoelectron studies of biological purines: the valence electronic structure of adenine.
Topics: 2-Aminopurine; Adenine; Chemical Phenomena; Chemistry, Physical; Spectrophotometry, Ultraviolet | 1976 |
[Eremothecium ashbyii mutants resistant to 2,6-diaminopurine].
Topics: 2-Aminopurine; Adenine; Ascomycota; Mutagens; Purines; Riboflavin; Saccharomycetales | 1975 |
Molecular and biochemical elucidation of a cellular phenotype characterized by adenine analogue resistance in the presence of high levels of adenine phosphoribosyltransferase activity.
Topics: 2-Aminopurine; Adenine; Adenine Phosphoribosyltransferase; Adenosine Monophosphate; Amino Acid Sequence; Animals; Azaserine; Base Sequence; DNA Mutational Analysis; Drug Resistance; Exons; Genes; Mice; Molecular Sequence Data; Neoplasm Proteins; Phenotype; Polymerase Chain Reaction; Transfection; Tumor Cells, Cultured | 1992 |
6-Dimethyl amino purine and 2-amino purine inhibit the induction of expression of milk protein genes by prolactin.
Topics: 2-Aminopurine; Adenine; Animals; Caseins; Cells, Cultured; Female; Gene Expression; Mammary Glands, Animal; Milk Proteins; Prolactin; Rabbits; RNA, Messenger | 1992 |
Adenovirus inhibition of cellular protein synthesis is prevented by the drug 2-aminopurine.
Topics: 2-Aminopurine; Adenine; Adenoviruses, Human; Cell Line; Cell Transformation, Viral; eIF-2 Kinase; Humans; Kinetics; Protein Biosynthesis; Protein Kinases; Protein Synthesis Inhibitors; Proteins; RNA | 1990 |
Binding of Hoechst 33258 and 4',6'-diamidino-2-phenylindole to self-complementary decadeoxynucleotides with modified exocyclic base substituents.
Topics: 2-Aminopurine; Adenine; Base Composition; Base Sequence; Bisbenzimidazole; Fluorescent Dyes; Indoles; Kinetics; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides | 1991 |
Premature mitosis induced in mammalian cells by the protein kinase inhibitors 2-aminopurine and 6-dimethylaminopurine.
Topics: 2-Aminopurine; Adenine; Animals; Caffeine; Cell Division; Cell Line; Chromosomes; Cricetinae; Drug Synergism; Fibroblasts; Mesocricetus; Mitosis; Phosphorylation; Protein Biosynthesis; Protein Kinase Inhibitors; Protein Processing, Post-Translational; RNA | 1990 |
Chemically induced premature mitosis: differential response in rodent and human cells and the relationship to cyclin B synthesis and p34cdc2/cyclin B complex formation.
Topics: 2-Aminopurine; Adenine; Animals; Caffeine; CDC2 Protein Kinase; Cell Line; Cricetinae; Cricetulus; Cyclins; Ethers, Cyclic; HeLa Cells; Humans; Kinetics; Macromolecular Substances; Mice; Mitosis; Okadaic Acid | 1991 |
2-Amino-N6-hydroxyadenine induces gene/point mutations and multiple-locus mutations, but not multilocus deletion mutations, in the ad-3 region of a two-component heterokaryon of Neurospora crassa.
Topics: 2-Aminopurine; Adenine; Alleles; Chromosome Deletion; DNA Damage; Genetic Complementation Test; Genotype; Mutagens; Neurospora crassa | 1991 |
Qualitative differences in the spectra of genetic damage in 2-aminopurine-induced ad-3 mutants between nucleotide excision-repair-proficient and -deficient strains of Neurospora crassa.
Topics: 2-Aminopurine; Adenine; Chromosome Deletion; DNA Damage; DNA Repair; Genes, Lethal; Genes, Recessive; Genetic Complementation Test; Genetic Linkage; Mutation; Neurospora crassa | 1991 |
2-Aminopurine abolishes EGF- and TPA-stimulated pp33 phosphorylation and c-fos induction without affecting the activation of protein kinase C.
Topics: 2-Aminopurine; Adenine; Adenosine Triphosphate; Animals; Base Sequence; Blotting, Northern; Cell Membrane; Cells, Cultured; Enzyme Induction; Epidermal Growth Factor; Membrane Proteins; Mice; Molecular Sequence Data; Nucleic Acid Hybridization; Oligonucleotide Probes; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Transcription Factors | 1990 |
The PurR mutation of Drosophila melanogaster confers resistance to purine and 2,6-diaminopurine by elevating adenosine deaminase activity.
Topics: 2-Aminopurine; Adenine; Adenosine Deaminase; Animals; Chromosome Mapping; Crosses, Genetic; Drosophila melanogaster; Female; Gene Expression Regulation, Enzymologic; Genetic Linkage; Genotype; Hot Temperature; Male; Mutation; Nucleoside Deaminases; Purines; Recombination, Genetic; Repressor Proteins | 1990 |
Genetic effects of 2-aminopurine in mammalian cells.
Topics: 2-Aminopurine; Adenine; Aneuploidy; Animals; Cells, Cultured; Cricetinae; DNA; DNA Replication; Flow Cytometry; Fluorescence; Mutation; Sister Chromatid Exchange | 1990 |
Biochemical basis of the prevention of 6-thiopurine toxicity by the nucleobases, hypoxanthine and adenine.
Topics: 2-Aminopurine; Adenine; Adenine Phosphoribosyltransferase; Antineoplastic Agents; Biological Transport; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine Monophosphate; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Promyelocytic, Acute; Mercaptopurine; Thioguanine; Thionucleotides; Tumor Cells, Cultured | 1990 |
Synthesis and in vivo antitumor activity of 2-amino-9H-purine-6-sulfenamide, -sulfinamide, and -sulfonamide and related purine ribonucleosides.
Topics: 2-Aminopurine; Adenine; Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Female; Leukemia L1210; Mice; Molecular Conformation; Molecular Structure; Purine Nucleosides; Ribonucleosides; Sulfonamides; X-Ray Diffraction | 1990 |
Biosynthesis of reovirus-specified polypeptides. 2-aminopurine increases the efficiency of translation of reovirus s1 mRNA but not s4 mRNA in transfected cells.
Topics: 2-Aminopurine; Adenine; Animals; Cells, Cultured; DNA, Viral; Eukaryotic Initiation Factor-2; Gene Expression; Genes, Viral; Protein Biosynthesis; Protein Kinase Inhibitors; Reoviridae; RNA, Messenger; Transfection; Viral Proteins | 1990 |
High sensitivity of Chinese hamster epithelial liver cells to toxic analogues of purines.
Topics: 2-Aminopurine; Adenine; Adenine Phosphoribosyltransferase; Animals; Azaguanine; Cells, Cultured; Cricetinae; Epithelial Cells; Epithelium; Hypoxanthine Phosphoribosyltransferase; Liver; Mutagenicity Tests; Pentosyltransferases; Thioguanine; Thymine Nucleotides | 1990 |
Phorbol ester-mediated induction of HIV-1 from a chronically infected promonocyte clone: blockade by protein kinase inhibitors and relationship to tat-directed trans-activation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Aminopurine; Adenine; Alkaloids; Cell Line; Clone Cells; Gene Products, tat; HIV-1; Humans; Idoxuridine; Isoquinolines; Lymphoma, Large B-Cell, Diffuse; Piperazines; Protein Kinase Inhibitors; Staurosporine; tat Gene Products, Human Immunodeficiency Virus; Tetradecanoylphorbol Acetate; Trans-Activators; Transcriptional Activation; Virus Replication | 1990 |
Perfluorodecanoic acid inactivation of a channel for 2-aminopurine in the L5178Y cell membrane and recovery of the channel.
Topics: 2-Aminopurine; Adenine; Animals; Biological Transport; Cell Line; Cell Membrane; Decanoic Acids; Fluorocarbons; Ion Channels; Kinetics; Leukemia L5178; Mice | 1986 |
Gene induction by interferons and double-stranded RNA: selective inhibition by 2-aminopurine.
Topics: 2-Aminopurine; Adenine; Animals; Cells, Cultured; Gene Expression Regulation; Humans; Interferons; Mice; Protein Kinases; RNA, Double-Stranded; RNA, Messenger; Time Factors; Transcription, Genetic; Transcriptional Activation | 1988 |
2-Aminopurine as a probe for mismatch repair in mammalian cells and its relationship to DNA methylation.
Topics: 2-Aminopurine; Adenine; Animals; Azacitidine; Cell Line; Clone Cells; Cricetinae; Cricetulus; Decitabine; DNA; DNA Repair; DNA Replication; Female; Methylation; Molecular Probes; Ovary | 1989 |
2-Aminopurine selectively blocks the transcriptional activation of cellular genes by virus, double-stranded RNA and interferons in human cells.
Topics: 2-Aminopurine; Adenine; Cell Line; Heat-Shock Proteins; Humans; Interferon Inducers; Interferons; Protein Kinase Inhibitors; RNA, Double-Stranded; Transcription, Genetic; Viruses | 1989 |
Effect of the uvs-2 allele of Neurospora crassa on the mutagenic potency of two N-hydroxylaminopurines and 2-aminopurine in the ad-3 forward-mutation test.
Topics: 2-Aminopurine; Adenine; Alleles; DNA Repair; Genes, Fungal; Mutagenicity Tests; Mutagens; Mutation; Neurospora; Neurospora crassa | 1989 |
Differential inhibition of nerve growth factor responses by purine analogues: correlation with inhibition of a nerve growth factor-activated protein kinase.
Topics: 2-Aminopurine; Adenine; Adrenal Gland Neoplasms; Animals; Axons; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Kinetics; Nerve Growth Factors; Nerve Regeneration; Ornithine Decarboxylase; Pheochromocytoma; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Thioguanine | 1989 |
Selection of an oral prodrug (BRL 42810; famciclovir) for the antiherpesvirus agent BRL 39123 [9-(4-hydroxy-3-hydroxymethylbut-l-yl)guanine; penciclovir].
Topics: 2-Aminopurine; Acyclovir; Adenine; Animals; Antiviral Agents; Bile; Biological Availability; Chromatography, High Pressure Liquid; Duodenum; Famciclovir; Guanine; Humans; In Vitro Techniques; Intestinal Mucosa; Liver; Male; Prodrugs; Rats; Tissue Distribution | 1989 |
Characterization of the high pH wobble structure of the 2-aminopurine.cytosine mismatch by N-15 NMR spectroscopy.
Topics: 2-Aminopurine; Adenine; Base Composition; Cytosine; Hydrogen Bonding; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Nitrogen Isotopes; Nucleic Acid Conformation | 1989 |
A mutation in the dam gene of Vibrio cholerae: 2-aminopurine sensitivity with intact GATC methylase activity.
Topics: 2-Aminopurine; Adenine; Aminacrine; Bacteriophages; Base Sequence; Conjugation, Genetic; Escherichia coli; Genes, Bacterial; Kinetics; Methyl Methanesulfonate; Mutation; Plasmids; Site-Specific DNA-Methyltransferase (Adenine-Specific); Substrate Specificity; Ultraviolet Rays; Vibrio cholerae | 1989 |
Prodrugs of the selective antiherpesvirus agent 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]guanine (BRL 39123) with improved gastrointestinal absorption properties.
Topics: 2-Aminopurine; Acyclovir; Adenine; Animals; Antiviral Agents; Chemical Phenomena; Chemistry; Famciclovir; Guanine; Intestinal Absorption; Mice; Prodrugs | 1989 |
2-Aminopurine abolishes epidermal growth factor-stimulated phosphorylation of complexed and chromatin-associated forms of a 33 kDa phosphoprotein.
Topics: 2-Aminopurine; Adenine; Animals; Cells, Cultured; Centrifugation, Density Gradient; Chromatin; Epidermal Growth Factor; Gene Expression Regulation; Humans; Mice; Mitogens; Molecular Weight; Peptide Mapping; Phosphoproteins; Phosphorylation; Ribosomal Protein S6; Ribosomal Proteins; RNA, Double-Stranded; Time Factors; Transcription, Genetic | 1989 |
Cleavage and sequence recognition of 2,6-diaminopurine-containing DNA by site-specific endonucleases.
Topics: 2-Aminopurine; Adenine; Base Sequence; DNA Restriction Enzymes; DNA, Viral; Kinetics; Substrate Specificity | 1987 |
Base pair opening dynamics of a 2-aminopurine substituted Eco RI restriction sequence and its unsubstituted counterpart in oligonucleotides.
Topics: 2-Aminopurine; Adenine; Base Composition; Base Sequence; Deoxyribonuclease EcoRI; DNA Restriction Enzymes; Fluorescent Dyes; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Spectrophotometry, Ultraviolet | 1987 |
DNA containing the base analogue 2-aminoadenine: preparation, use as hybridization probes and cleavage by restriction endonucleases.
Topics: 2-Aminopurine; Adenine; Base Sequence; DNA; DNA Restriction Enzymes; Indicators and Reagents; Molecular Sequence Data; Nucleic Acid Hybridization; Oligodeoxyribonucleotides; Templates, Genetic | 1988 |
Isolation of mutants sensitive to 2-aminopurine and alkylating agents and evidence for the role of DNA methylation in Penicillium chrysogenum.
Topics: 2-Aminopurine; Adenine; Alkylating Agents; DNA Repair; DNA Restriction Enzymes; DNA, Bacterial; Methylation; Mutation; Penicillium; Penicillium chrysogenum | 1986 |
Preparative electrochemical reduction of 2-amino-6-chloropurine and synthesis of 6-deoxyacyclovir, a fluorescent substrate of xanthine oxidase and a prodrug of acyclovir.
Topics: 2-Aminopurine; Acyclovir; Adenine; Animals; Antiviral Agents; Electrolysis; Guinea Pigs; Herpes Simplex; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Polarography; Prodrugs; Simplexvirus; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Viral Plaque Assay; Xanthine Oxidase | 1987 |
[Weakening of type I restriction in E. coli: the effect of 2-aminopurine and 5-bromouracil].
Topics: 2-Aminopurine; Adenine; Bromouracil; Deoxyribonucleases, Type I Site-Specific; DNA Repair; DNA Restriction Enzymes; Escherichia coli; Mutation | 1987 |
A new approach to the synthesis of a protected 2-aminopurine derivative and its incorporation into oligodeoxynucleotides containing the Eco RI and Bam HI recognition sites.
Topics: 2-Aminopurine; Adenine; Base Sequence; Deoxyribonuclease BamHI; Deoxyribonuclease EcoRI; DNA Restriction Enzymes; Indicators and Reagents; Magnetic Resonance Spectroscopy; Oligodeoxyribonucleotides; Substrate Specificity | 1988 |
Two N-hydroxylaminopurines are highly mutagenic in the ad-3 forward-mutation test in growing cultures of heterokaryon 12 of Neurospora crassa.
Topics: 2-Aminopurine; Adenine; Dose-Response Relationship, Drug; Genes, Fungal; Mutagenicity Tests; Neurospora; Neurospora crassa | 1987 |
2-Aminopurine and 5-bromouracil induce alleviation of type I restriction in Escherichia coli: mismatches function as inducing signals?
Topics: 2-Aminopurine; Adenine; Bacteriophage lambda; Bromouracil; Deoxyribonucleases, Type I Site-Specific; Escherichia coli; Genotype; Phenotype | 1988 |
Induction of the SOS system in a dam-3 mutant: a diagnostic strain for chemicals causing DNA mismatches.
Topics: 2-Aminopurine; Adenine; Bacterial Proteins; Bromodeoxyuridine; DNA Damage; DNA Repair; DNA, Bacterial; Escherichia coli; Ethyl Methanesulfonate; Gene Expression Regulation; Genes, Bacterial; Methyltransferases; Mutagenicity Tests; Recombinant Fusion Proteins; Site-Specific DNA-Methyltransferase (Adenine-Specific); SOS Response, Genetics | 1987 |
In vivo studies of repair of 2-aminopurine in Escherichia coli.
Topics: 2-Aminopurine; Adenine; DNA Repair; DNA, Bacterial; Escherichia coli; Genes, Bacterial; Methyltransferases; Mutation; Site-Specific DNA-Methyltransferase (Adenine-Specific); Temperature | 1988 |
Different methods of graphite electrode treatment and their effect on the electrochemical behavior of a small adsorbing biological molecule, 2,6-diamino-8-purinol.
Topics: 2-Aminopurine; Adenine; Electrochemistry; Electrodes; Graphite; Hydrogen-Ion Concentration | 1988 |
Crystal structure of a Z-DNA fragment containing thymine/2-aminoadenine base pairs.
Topics: 2-Aminopurine; Adenine; Base Composition; Circular Dichroism; Crystallization; DNA; Nucleic Acid Conformation; Thymine | 1986 |
2-Aminopurine selectively inhibits the induction of beta-interferon, c-fos, and c-myc gene expression.
Topics: 2-Aminopurine; Adenine; Animals; Cells, Cultured; Gene Expression Regulation; Heat-Shock Proteins; Humans; Interferon Type I; Mice; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogenes; Regulatory Sequences, Nucleic Acid; Transcription, Genetic | 1988 |
Thermodynamic studies of base pairing involving 2,6-diaminopurine.
Topics: 2-Aminopurine; Adenine; Base Composition; Oligodeoxyribonucleotides; Thermodynamics | 1988 |
Interferon induction by viruses. XVI. 2-Aminopurine blocks selectively and reversibly an early stage in interferon induction.
Topics: 2-Aminopurine; Adenine; Animals; Chick Embryo; Dactinomycin; Depression, Chemical; eIF-2 Kinase; Fibroblasts; Gene Expression Regulation; Heat-Shock Proteins; Interferon Inducers; Interferon Type I; L Cells; Protein Kinase Inhibitors; Protein Kinases; RNA, Double-Stranded; Viral Plaque Assay | 1988 |
Base pairing and mutagenesis: observation of a protonated base pair between 2-aminopurine and cytosine in an oligonucleotide by proton NMR.
Topics: 2-Aminopurine; Adenine; Cytosine; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Mutation; Oligodeoxyribonucleotides; Temperature | 1986 |
Mutagenic and comutagenic effects of ethionine in Escherichia coli K12.
Topics: 2-Aminopurine; Adenine; Bacterial Proteins; DNA (Cytosine-5-)-Methyltransferases; DNA Repair; DNA, Bacterial; Drug Synergism; Escherichia coli; Ethionine; Methylation; Rec A Recombinases | 1986 |
NMR studies on an oligodeoxynucleotide containing 2-aminopurine opposite adenine.
Topics: 2-Aminopurine; Adenine; Base Composition; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Oligodeoxyribonucleotides | 1987 |
Synthesis and properties of defined DNA oligomers containing base mispairs involving 2-aminopurine.
Topics: 2-Aminopurine; Adenine; Base Composition; Base Sequence; DNA; Hydrogen Bonding; Indicators and Reagents; Magnetic Resonance Spectroscopy; Oligodeoxyribonucleotides; Spectrophotometry, Ultraviolet | 1986 |
Induction of adenine salvage in mouse cell lines deficient in adenine phosphoribosyltransferase.
Topics: 2-Aminopurine; Adenine; Adenine Phosphoribosyltransferase; Alanine; Animals; Azaserine; Cell Line; Cross Reactions; Drug Resistance; Gene Expression Regulation; Karyotyping; Mice; Mycoplasma; Pentosyltransferases | 1985 |
Ribonucleoside and deoxyribonucleoside triphosphate pools during 2-aminopurine mutagenesis in T4 mutator-, wild type-, and antimutator-infected Escherichia coli.
Topics: 2-Aminopurine; Adenine; Alleles; Deoxyribonucleotides; DNA-Directed DNA Polymerase; Escherichia coli; Mutation; Ribonucleotides; T-Phages | 1985 |
An explanation of the induction of mutations by 2-aminopurine from an ab initio molecular orbital study.
Topics: 2-Aminopurine; Adenine; Base Composition; Chemical Phenomena; Chemistry; Cytosine; DNA; Hydrogen Bonding; Mutagens; Mutation | 1986 |
The biochemical basis of 5-bromouracil- and 2-aminopurine-induced mutagenesis.
Topics: 2-Aminopurine; Adenine; Base Composition; Bromouracil; Cytosine; Deoxycytosine Nucleotides; Deoxyribonucleotides; Deoxyuracil Nucleotides; Guanine; Mutation; Nucleic Acid Heteroduplexes; Thymine | 1985 |
Mode of action of 2-amino-6-chloro-1-deazapurine.
Topics: 2-Aminopurine; Adenine; AMP Deaminase; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line; Cell Survival; Glycine; Humans; Hypoxanthine; Hypoxanthines; IMP Dehydrogenase; Laryngeal Neoplasms; Leukemia L1210; Macromolecular Substances; Mice; Nucleotides; Ribonucleotides; Structure-Activity Relationship | 1984 |
Effects of purine amino groups on the development of Drosophila.
Topics: 2-Aminopurine; Adenine; Animals; Charcoal; Drosophila melanogaster; Guanine; Larva; Purines | 1984 |
[2-Aminopurine, analog of adenine, induces a nonmutagenic repair mechanism acting upon UV lesions of double-stranded DNA in E. coli].
Topics: 2-Aminopurine; Adenine; Bacteriophage lambda; DNA Polymerase I; DNA Repair; DNA, Viral; Escherichia coli; Mutation; Ultraviolet Rays | 1982 |
2-aminopurine induced DNA repair in E. coli.
Topics: 2-Aminopurine; Adenine; Bacteriophage lambda; Bacteriophage phi X 174; DNA; DNA Repair; DNA, Single-Stranded; DNA, Viral; Escherichia coli; Recombination, Genetic; Ultraviolet Rays; Virus Activation | 1982 |
Incorporation into DNA of the base analog 2-aminopurine by the Epstein-Barr virus-induced DNA polymerase in vivo and in vitro.
Topics: 2-Aminopurine; Adenine; Adenine Nucleotides; Cells, Cultured; DNA-Directed DNA Polymerase; DNA, Viral; Enzyme Induction; Herpesvirus 4, Human; Humans; Structure-Activity Relationship; Substrate Specificity; Virus Replication | 1981 |
Ethionine abolishes mutagenesis by 9-aminoacridine (but not by 2-aminopurine) in Salmonella plate tests.
Topics: 2-Aminopurine; Adenine; Aminoacridines; Ethionine; Mutagenicity Tests; Mutagens; Salmonella typhimurium | 1983 |
Involvement of the mismatch repair system in base analogue-induced mutagenesis.
Topics: 2-Aminopurine; Adenine; Base Composition; DNA Repair; Escherichia coli; Genes, Bacterial; Mutation | 1983 |
Influence of local nucleotide sequence on substitution of 2-aminopurine for adenine during deoxyribonucleic acid synthesis in vitro.
Topics: 2-Aminopurine; Adenine; Base Sequence; DNA; DNA Nucleotidylexotransferase; DNA Polymerase I; DNA Replication; DNA-Directed DNA Polymerase; Escherichia coli; T-Phages | 1983 |
Mutagenesis and anti-mutagenesis in Salmonella: influence of ethionine and caffeine on yields of mutations induced by 2-aminopurine and 9-aminoacridine.
Topics: 2-Aminopurine; Adenine; Aminacrine; Aminoacridines; Caffeine; Ethionine; Mutagenicity Tests; Mutagens; Mutation; Salmonella typhimurium; Species Specificity | 1983 |
Induction of damage inducible (SOS) repair in dam mutants of Escherichia coli exposed to 2-aminopurine.
Topics: 2-Aminopurine; Adenine; DNA (Cytosine-5-)-Methyltransferases; DNA Repair; DNA, Bacterial; Enzyme Induction; Escherichia coli; Methyltransferases; Site-Specific DNA-Methyltransferase (Adenine-Specific) | 1984 |
On the molecular basis of transition mutations. Frequency of forming 2-aminopurine-cytosine base mispairs in the G X C----A X T mutational pathway by T4 DNA polymerase in vitro.
Topics: 2-Aminopurine; Adenine; Base Sequence; Cytosine; DNA-Directed DNA Polymerase; Mutation; Polydeoxyribonucleotides; T-Phages; Templates, Genetic; Time Factors | 1984 |
2NH2A X T helices in the ribo- and deoxypolynucleotide series. Structural and energetic consequences of 2NH2A substitution.
Topics: 2-Aminopurine; Adenine; Base Composition; Nucleic Acid Conformation; Polydeoxyribonucleotides; Polyribonucleotides; Thermodynamics | 1984 |
Evidence of 2-aminopurine-cytosine base mispairs involving two hydrogen bonds.
Topics: 2-Aminopurine; Adenine; Base Composition; Cytosine; DNA; Hydrogen Bonding; Nucleic Acid Conformation; Nucleic Acid Denaturation; Polydeoxyribonucleotides; Spectrophotometry, Ultraviolet; Temperature; Thymine | 1983 |
Mechanism of mutation at the aprt locus in Chinese hamster ovary cells: analysis of heterozygotes and hemizygotes.
Topics: 2-Aminopurine; Adenine; Adenine Phosphoribosyltransferase; Animals; Cell Line; Chromosome Deletion; Cricetinae; Cricetulus; Drug Resistance; Female; Fibroblasts; Heterozygote; Models, Genetic; Mutation; Ovary; Pentosyltransferases | 1983 |
Poly(d2NH2A-dT): effect of 2-amino substituent on the B to Z transition.
Topics: 2-Aminopurine; Adenine; Circular Dichroism; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Poly dA-dT; Polydeoxyribonucleotides; Spectrophotometry, Infrared; Structure-Activity Relationship | 1984 |
Utilization of 2,6-diaminopurine by Salmonella typhimurium.
Topics: 2-Aminopurine; Adenine; Adenosine Deaminase; Guanine; Mutation; Purine-Nucleoside Phosphorylase; Purines; Salmonella typhimurium | 1980 |
Deoxyribonucleotide pools, base pairing, and sequence configuration affecting bromodeoxyuridine- and 2-aminopurine-induced mutagenesis.
Topics: 2-Aminopurine; Adenine; Adenosine Deaminase Inhibitors; Base Sequence; Bromodeoxyuridine; Deoxyribonucleotides; DNA; DNA Replication; Hydrogen Bonding; Mutagens; Structure-Activity Relationship | 1980 |
On the molecular basis of transition mutations: frequencies of forming 2-aminopurine.cytosine and adenine.cytosine base mispairs in vitro.
Topics: 2-Aminopurine; Adenine; Animals; Base Composition; Carcinoma; Cattle; Cell Line; Cytosine; DNA; DNA Nucleotidyltransferases; DNA Polymerase II; DNA-Directed DNA Polymerase; Humans; Kinetics; Mouth Neoplasms; Mutation; Templates, Genetic; Thymus Gland | 1981 |
Induction of gene mutation in and cell transformation of mammalian cells by modified purines: 2-aminopurine and 6-N-hydroxylaminopurine.
Topics: 2-Aminopurine; Adenine; Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Mesocricetus; Mutation | 1981 |
Kinetic measurement of 2-aminopurine X cytosine and 2-aminopurine X thymine base pairs as a test of DNA polymerase fidelity mechanisms.
Topics: 2-Aminopurine; Adenine; Animals; Cattle; DNA Replication; DNA-Directed DNA Polymerase; Humans; Hydrogen Bonding; Kinetics; Structure-Activity Relationship; Substrate Specificity; Thermodynamics | 1982 |
Mechanism of 2-aminopurine mutagenesis in mouse T-lymphosarcoma cells.
Topics: 2-Aminopurine; Adenine; Animals; Base Sequence; Cell Line; Cytidine Triphosphate; DNA; DNA Repair; DNA Replication; Lymphoma, Non-Hodgkin; Mice; Mutagens; T-Lymphocytes; Thymine Nucleotides | 1982 |
Comparison of mutagenic and recombinogenic effects of some adenine analogues in Saccharomyces cerevisiae D7.
Topics: 2-Aminopurine; Adenine; Dose-Response Relationship, Drug; Mutagens; Recombination, Genetic; Saccharomyces cerevisiae | 1981 |
Mutational specificity of the base analogue, 2-aminopurine, in Escherichia coli.
Topics: 2-Aminopurine; Adenine; Escherichia coli; Mutagens; Mutation; Recombination, Genetic; Transduction, Genetic | 1981 |
Nonrandom substitution of 2-aminopurine for adenine during deoxyribonucleic acid synthesis in vitro.
Topics: 2-Aminopurine; Adenine; Base Sequence; DNA Polymerase I; DNA Polymerase II; DNA Replication; DNA-Directed DNA Polymerase; Escherichia coli; Kinetics; Substrate Specificity; T-Phages | 1981 |
Influence of diverse gene 43 DNA polymerases on the incorporation and replication in vivo of 2-aminopurine at A X T base-pairs in bacteriophage T4.
Topics: 2-Aminopurine; Adenine; Base Composition; DNA Replication; DNA-Directed DNA Polymerase; DNA, Viral; Genes, Viral; Mutation; T-Phages; Templates, Genetic; Virus Replication | 1981 |
The purine 2-amino group as a critical recognition element for binding of small molecules to DNA.
Topics: 2-Aminopurine; Adenine; Anti-Bacterial Agents; Autoradiography; Base Sequence; Dactinomycin; Deoxyribonuclease I; DNA; Echinomycin; Guanine; Inosine; Molecular Sequence Data; Netropsin; Nucleic Acid Conformation; RNA, Transfer, Tyr | 1994 |
Isolation and characterization of mutations in the mouse APRT gene that encode functional enzymes with resistance to toxic adenine analogs.
Topics: 2-Aminopurine; Adenine; Adenine Phosphoribosyltransferase; Animals; Carcinoma, Embryonal; Cell Division; Cell Line; Ethyl Methanesulfonate; Kinetics; Mice; Mutagenesis; Tumor Cells, Cultured; Ultraviolet Rays | 1994 |
Transferring the purine 2-amino group from guanines to adenines in DNA changes the sequence-specific binding of antibiotics.
Topics: 2-Aminopurine; Adenine; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Base Sequence; Binding Sites; Dinucleoside Phosphates; DNA; Guanine; Inosine; Intercalating Agents; Ligands; Molecular Sequence Data; Peptides; RNA, Transfer, Tyr | 1995 |
Substitution of 2-aminoadenine and 5-methylcytosine for adenine and cytosine in hybridization probes increases the sensitivity of DNA fingerprinting.
Topics: 2-Aminopurine; 5-Methylcytosine; Adenine; Base Sequence; Blotting, Southern; Cytosine; DNA; DNA Fingerprinting; DNA Primers; Humans; Molecular Sequence Data; Oligonucleotide Probes; Sensitivity and Specificity | 1994 |
Progesterone but not ras requires MPF for in vivo activation of MAPK and S6 KII: MAPK is an essential conexion point of both signaling pathways.
Topics: 2-Aminopurine; Adenine; Animals; Calcium-Calmodulin-Dependent Protein Kinases; CDC2 Protein Kinase; Cell Cycle; Cycloheximide; Enzyme Activation; Female; In Vitro Techniques; Maturation-Promoting Factor; Microinjections; Mitosis; Oocytes; Progesterone; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins p21(ras); Ribosomal Protein S6 Kinases; Xenopus laevis | 1994 |
A simple method for N-15 labelling of exocyclic amino groups in synthetic oligodeoxynucleotides.
Topics: 2-Aminopurine; Adenine; Ammonia; Base Sequence; Chromatography, High Pressure Liquid; Cytosine; Guanine; Isotope Labeling; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Nitrogen Isotopes; Oligodeoxyribonucleotides | 1994 |
2-Aminopurine labelled RNA bulge loops. Synthesis and thermodynamics.
Topics: 2-Aminopurine; Adenine; Antimetabolites; Fluorescent Dyes; Nucleic Acid Conformation; RNA; Spectrometry, Fluorescence; Thermodynamics | 1996 |
Targeted base stacking disruption by the EcoRI DNA methyltransferase.
Topics: 2-Aminopurine; Adenine; Biological Assay; DNA; Models, Molecular; Nucleic Acid Conformation; Site-Specific DNA-Methyltransferase (Adenine-Specific); Spectrometry, Fluorescence | 1996 |
Dam methyltransferase from Escherichia coli: kinetic studies using modified DNA oligomers: nonmethylated substrates.
Topics: 2-Aminopurine; Adenine; Base Sequence; DNA Methylation; DNA Probes; DNA, Bacterial; Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Guanine; Hypoxanthine; Kinetics; Molecular Sequence Data; Nucleic Acid Heteroduplexes; Oligonucleotide Probes; Site-Specific DNA-Methyltransferase (Adenine-Specific); Software; Substrate Specificity; Temperature; Thermodynamics; Thymine; Uracil | 1997 |
Effects of diaminopurine and inosine substitutions on A-tract induced DNA curvature. Importance of the 3'-A-tract junction.
Topics: 2-Aminopurine; Adenine; Base Sequence; Deoxyribonuclease EcoRI; Deoxyribonucleases, Type II Site-Specific; DNA; Electrophoresis, Polyacrylamide Gel; Inosine; Nucleic Acid Conformation; Photochemistry; Polymerase Chain Reaction; Repetitive Sequences, Nucleic Acid; Structure-Activity Relationship; Uranyl Nitrate | 1997 |
High affinity binding of MEF-2C correlates with DNA bending.
Topics: 2-Aminopurine; Adenine; Amino Acid Sequence; Binding Sites; DNA; DNA-Binding Proteins; Escherichia coli; MEF2 Transcription Factors; Molecular Sequence Data; Myogenic Regulatory Factors; Nucleic Acid Conformation; Protein Binding; Purines; Recombinant Fusion Proteins; Transcription Factors | 1997 |
Increased DNA binding and sequence discrimination of PNA oligomers containing 2,6-diaminopurine.
Topics: 2-Aminopurine; Adenine; DNA; Molecular Mimicry; Nucleic Acids; Nylons; Peptides | 1997 |
Protein synthesis in pseudorabies virus-infected cells: decreased expression of protein kinase PKR, and effects of 2-aminopurine and adenine.
Topics: 2-Aminopurine; Adenine; Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Cell Line; eIF-2 Kinase; Electrophoresis, Polyacrylamide Gel; Herpesvirus 1, Suid; Mice; Mitogen-Activated Protein Kinase 1; Protein Biosynthesis; Swine; Time Factors | 1998 |
Compression of the DNA minor groove is responsible for termination of DNA synthesis by HIV-1 reverse transcriptase.
Topics: 2-Aminopurine; Adenine; Base Sequence; DNA; DNA, Viral; HIV Reverse Transcriptase; HIV-1; Hydroxyl Radical; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; RNA-Directed DNA Polymerase | 1999 |
Electron transfer between bases in double helical DNA.
Topics: 2-Aminopurine; Adenine; Base Pairing; DNA; Electrons; Guanine; Hydrogen Bonding; Kinetics; Light; Nucleic Acid Conformation; Oxidation-Reduction; Spectrometry, Fluorescence; Thermodynamics | 1999 |
Effect of base analog substitutions in the specific GATC site on binding and methylation of oligonucleotide duplexes by the bacteriophage T4 Dam DNA-[N6-adenine] methyltransferase.
Topics: 2-Aminopurine; Adenine; Bacteriophage T4; Binding Sites; DNA Methylation; Guanine; Kinetics; Mutagenesis, Site-Directed; Oligonucleotides; Purines; Site-Specific DNA-Methyltransferase (Adenine-Specific); Viral Proteins | 1999 |
Electronic spectra of adenine and 2-aminopurine: an ab initio study of energy level diagrams of different tautomers in gas phase and aqueous solution.
Topics: 2-Aminopurine; Adenine; DNA; Fluorescence; Mutation; Spectrum Analysis | 2000 |
Molecular enzymology of the EcoRV DNA-(Adenine-N (6))-methyltransferase: kinetics of DNA binding and bending, kinetic mechanism and linear diffusion of the enzyme on DNA.
Topics: 2-Aminopurine; Adenine; Base Sequence; Binding, Competitive; Catalysis; Coenzymes; Diffusion; DNA; DNA Methylation; DNA-Binding Proteins; Escherichia coli; Fluorescence; Kinetics; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Protein Binding; S-Adenosylhomocysteine; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific); Substrate Specificity; Thermodynamics | 2000 |
Femtosecond direct observation of charge transfer between bases in DNA.
Topics: 2-Aminopurine; Adenine; Base Pairing; DNA; Electron Transport; Guanine; Inosine; Models, Molecular; Time Factors | 2000 |
[Current treatment of hepatitis B].
Topics: 2-Aminopurine; Adenine; Anti-Inflammatory Agents; Antiviral Agents; DNA Replication; Famciclovir; Forecasting; Hepatitis B; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Organophosphonates; Prednisone; Prognosis; Reverse Transcriptase Inhibitors; Time Factors; Virus Replication | 2001 |
Importance of specific nucleotides in the folding of the natural form of the hairpin ribozyme.
Topics: 2-Aminopurine; Adenine; Base Composition; Base Sequence; Carbocyanines; Cytosine; Deoxyribonucleosides; Energy Transfer; Fluorescein; Fluorescent Dyes; Guanine; Hydrolysis; Molecular Sequence Data; Nepovirus; Nucleic Acid Conformation; Oligonucleotides; Point Mutation; Purine Nucleotides; Ribose; RNA, Catalytic; Spectrometry, Fluorescence; Uridine | 2001 |
Design and evaluation of a tryptophanless RecA protein with wild type activity.
Topics: 2-Aminopurine; Adenine; Cell Survival; DNA; DNA, Single-Stranded; Dose-Response Relationship, Radiation; Electrophoresis, Polyacrylamide Gel; Hydrolysis; Models, Molecular; Mutagenesis, Site-Directed; Mutagens; Mutation; Promoter Regions, Genetic; Protein Binding; Protein Structure, Tertiary; Rec A Recombinases; Spectrometry, Fluorescence; Tryptophan; Ultraviolet Rays | 2001 |
Nonenzymatic oligomerization reactions on templates containing inosinic acid or diaminopurine nucleotide residues.
Topics: 2-Aminopurine; Adenine; Adenosine; Adenosine Monophosphate; Base Pairing; Cytidine Monophosphate; Cytosine; DNA Primers; Evolution, Chemical; Evolution, Molecular; Exobiology; Guanine; Inosine Monophosphate; RNA; Templates, Genetic; Uracil; Uridine Monophosphate | 1999 |
5-propynyluracil.diaminopurine: an efficient base-pair for non-enzymatic transcription of DNA.
Topics: 2-Aminopurine; Adenine; Alkynes; Autoradiography; Base Pairing; DNA Replication; Electrophoresis, Polyacrylamide Gel; Templates, Genetic; Transcription, Genetic; Uracil | 2002 |
Treatment of recurrent hepatitis B infection in liver transplant recipients.
Topics: 2-Aminopurine; Adenine; Antiviral Agents; Famciclovir; Hepatitis B; Humans; Interferon-alpha; Lamivudine; Liver Transplantation; Organophosphonates; Recurrence; Reverse Transcriptase Inhibitors | 2002 |
Functional group requirements in the probable active site of the VS ribozyme.
Topics: 2-Aminopurine; Adenine; Base Sequence; Binding Sites; Catalysis; Endoribonucleases; Hydrolysis; Imidazoles; Molecular Sequence Data; Nucleic Acid Conformation; RNA, Catalytic; Spectrometry, Fluorescence | 2002 |
Optimisation of the 10-23 DNAzyme-substrate pairing interactions enhanced RNA cleavage activity at purine-cytosine target sites.
Topics: 2-Aminopurine; Adenine; Base Pairing; Base Sequence; Catalysis; Cytosine; DNA, Catalytic; DNA, Single-Stranded; Guanine; Hydrogen Bonding; Kinetics; Nucleic Acid Conformation; RNA; RNA, Catalytic; Substrate Specificity | 2003 |
Immunobiological activity of N-[2-(phosphonomethoxy)alkyl] derivatives of N6-substituted adenines, and 2,6-diaminopurines.
Topics: 2-Aminopurine; Adenine; Adjuvants, Immunologic; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Female; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Organophosphonates; Organophosphorus Compounds; Tenofovir | 2003 |
Cytological studies on the antimetabolite action of 2, 6-diaminopurine in Vicia faba roots.
Topics: 2-Aminopurine; Adenine; Adenosine; Antimetabolites; Cell Division; Deoxyadenosines; DNA; Growth; Guanine; Hypoxanthine; Purines; Vicia faba | 1955 |
Metabolism of 2,6-diaminopurine: S-adenosylmethionine as methyl donor for 2-methylamino-6-aminopurine synthesis.
Topics: 2-Aminopurine; Adenine; Adenosine; Metabolic Networks and Pathways; Methionine; Purines; S-Adenosylmethionine | 1959 |
KINETIN-LIKE GROWTH-PROMOTING ACTIVITY OF 1-SUBSTITUTED ADENINES (1-BENZYL-6-AMINOPURINE AND 1-(GAMMA, GAMMA-DIMETHYLALLYL)-6-AMINOPURINE.
Topics: 2-Aminopurine; Adenine; Chlorophyll; Kinetin; Nerve Growth Factors; Nicotiana; Pharmacology; Plant Growth Regulators; Purines; Research | 1964 |
INFLUENCE OF MUTAGENS ON THE INITIATION OF SKIN CARCINOGENESIS.
Topics: 2-Aminopurine; Acridines; Adenine; Carcinogenesis; Carcinogens; Idoxuridine; Lung Neoplasms; Mice; Mutagens; Nucleosides; Pharmacology; Purines; Research; Skin Neoplasms; Thymidine; Toxicology; Tritium; Urethane | 1964 |
CARBAMATES DERIVED FROM AMINOPURINES.
Topics: 2-Aminopurine; Adenine; Animals; Antineoplastic Agents; Carbamates; Chemistry, Pharmaceutical; Leukemia L1210; Pharmacology; Purines; Pyrimidines; Research; Sarcoma 180 | 1963 |
IDENTIFICATION OF THE ALTERED BASES IN MUTATED SINGLE-STRANDED DNA. II. IN VIVO MUTAGENESIS BY 5-BROMODEOXYURIDINE AND 2-AMINOPURINE.
Topics: 2-Aminopurine; Adenine; Antineoplastic Agents; Bromodeoxyuridine; Coliphages; Cytosine; Cytosine Nucleotides; DNA; DNA, Single-Stranded; DNA, Viral; Guanine; Guanine Nucleotides; Mutagenesis; Mutation; Nucleosides; Purines; Research; Thymidine; Thymine | 1964 |
ANTAGONISM BETWEEN PURINES IN PURINE-REQUIRING BACILLUS SUBTILIS MUTANTS.
Topics: 2-Aminopurine; Adenine; Adenine Nucleotides; Azaguanine; Bacillus subtilis; Guanine; Guanine Nucleotides; Hypoxanthines; Mercaptopurine; Metabolism; Mutation; Nucleosides; Nucleotides; Pharmacology; Purines; Research; Xanthines | 1964 |
Synthesis of base substituted 2-hydroxy-3-(purin-9-yl)-propanoic acids and 4-(purin-9-yl)-3-butenoic acids.
Topics: 2-Aminopurine; Adenine; Antineoplastic Agents; Antiviral Agents; Butyrates; Guanine; Hypoxanthines; Lactic Acid; Magnetic Resonance Spectroscopy; Molecular Structure; Purines | 2003 |
Factors related to the growth of psittacosis virus (strain 6BC) II. Purines, pyrimidines, and other components related to nucleic acid.
Topics: 2-Aminopurine; Adenine; Benzimidazoles; Guanine; Nucleic Acids; Psittacosis; Pterins; Purines; Pyrimidines | 1952 |
In vitro selection of drug-resistant varicella-zoster virus (VZV) mutants (OKA strain): differences between acyclovir and penciclovir?
Topics: 2-Aminopurine; Acyclovir; Adenine; Antiviral Agents; Arabinofuranosyluracil; Bromodeoxyuridine; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Multiple, Viral; Drug Resistance, Viral; Foscarnet; Guanine; Herpesvirus 3, Human; Humans; Microbial Sensitivity Tests; Mutation; Organophosphonates; Phenotype; Selection, Genetic; Thymidine Kinase; Viral Proteins | 2004 |
The kinetics of ligand binding by an adenine-sensing riboswitch.
Topics: 2-Aminopurine; 5' Untranslated Regions; Adenine; Bacillus subtilis; Bacterial Proteins; Dose-Response Relationship, Drug; Gene Expression Regulation, Bacterial; Genes, Reporter; Hot Temperature; Kinetics; Ligands; Microscopy, Fluorescence; Nucleic Acid Conformation; Protein Binding; RNA; RNA, Messenger; Temperature; Thermodynamics; Time Factors; Transcription, Genetic | 2005 |
A selective, noncovalent assay for base flipping in DNA.
Topics: 2-Aminopurine; Adenine; Base Pairing; DNA; Fluorescence; Kinetics; Models, Molecular; Nucleic Acid Conformation; Thymine; Titrimetry | 2005 |
Purine P1 receptor-dependent immunostimulatory effects of antiviral acyclic analogues of adenine and 2,6-diaminopurine.
Topics: 2-Aminopurine; Adenine; Adjuvants, Immunologic; Animals; Anti-HIV Agents; Caffeine; Cell Survival; Cells, Cultured; Chemokine CCL3; Chemokine CCL4; Chemokine CCL5; Dihydropyridines; Dose-Response Relationship, Drug; Female; Flavins; Humans; Interleukin-10; Lipopolysaccharides; Macrophage Inflammatory Proteins; Macrophages; Mice; Mice, Inbred C57BL; Molecular Structure; Organophosphonates; Purinergic P1 Receptor Antagonists; Quinazolines; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Theophylline; Triazoles; Tumor Necrosis Factor-alpha | 2006 |
Aminoglycoside-induced reduction in nucleotide mobility at the ribosomal RNA A-site as a potentially key determinant of antibacterial activity.
Topics: 2-Aminopurine; Adenine; Aminoglycosides; Anti-Bacterial Agents; Binding Sites; Carbohydrate Sequence; Escherichia coli; Molecular Sequence Data; Paromomycin; Ribostamycin; RNA, Ribosomal, 16S; Spectrometry, Fluorescence | 2006 |
Structural fluctuations and excitation transfer between adenine and 2-aminopurine in single-stranded deoxytrinucleotides.
Topics: 2-Aminopurine; Adenine; DNA, Single-Stranded; Energy Transfer; Models, Chemical; Molecular Structure; Temperature; Time Factors | 2006 |
Thermodynamic and kinetic characterization of ligand binding to the purine riboswitch aptamer domain.
Topics: 2-Aminopurine; 5' Untranslated Regions; Adenine; Aptamers, Nucleotide; Guanine; Ligands; Models, Molecular; Mutation; Nucleic Acid Conformation; Purines; Pyrimidines; Regulatory Sequences, Ribonucleic Acid; RNA, Bacterial; Thermodynamics | 2006 |
Adenine and 2-aminopurine: paradigms of modern theoretical photochemistry.
Topics: 2-Aminopurine; Adenine; Energy Transfer; Fluorescence; Photochemistry | 2006 |
Recombination R-triplex: H-bonds contribution to stability as revealed with minor base substitutions for adenine.
Topics: 2-Aminopurine; Adenine; DNA; Hydrogen Bonding; Nucleic Acid Conformation; Recombination, Genetic; Thermodynamics; Tubercidin | 2006 |
Folding of the adenine riboswitch.
Topics: 2-Aminopurine; Adenine; Aptamers, Nucleotide; Bacillus subtilis; Binding Sites; Fluorescence Resonance Energy Transfer; Ligands; Magnesium; Nucleic Acid Conformation; RNA | 2006 |
Core requirements of the adenine riboswitch aptamer for ligand binding.
Topics: 2-Aminopurine; Adenine; Aptamers, Nucleotide; Base Pairing; Base Sequence; Fluorescence; Gene Expression Regulation; Ligands; Molecular Sequence Data; Nucleic Acid Conformation; Regulatory Sequences, Ribonucleic Acid | 2007 |
Defining the mode, energetics and specificity with which a macrocyclic hexaoxazole binds to human telomeric G-quadruplex DNA.
Topics: 2-Aminopurine; Adenine; Antineoplastic Agents; Binding Sites; DNA; Entropy; G-Quadruplexes; Humans; Ligands; Models, Molecular; Nucleic Acid Conformation; Oxazoles; Spectrometry, Fluorescence; Telomere | 2007 |
Structure and dynamics in DNA looped domains: CAG triplet repeat sequence dynamics probed by 2-aminopurine fluorescence.
Topics: 2-Aminopurine; Adenine; Base Composition; Base Sequence; DNA; Fluorescent Dyes; Humans; Kinetics; Models, Chemical; Molecular Sequence Data; Nucleic Acid Conformation; Nucleic Acid Denaturation; Nucleic Acid Heteroduplexes; Oligodeoxyribonucleotides; Spectrometry, Fluorescence; Structure-Activity Relationship; Temperature; Thermodynamics; Trinucleotide Repeat Expansion; Trinucleotide Repeats | 2007 |
Back-electron transfer suppresses the periodic length dependence of DNA-mediated charge transport across adenine tracts.
Topics: 2-Aminopurine; Adenine; Anthraquinones; Base Sequence; DNA; Electrons; Models, Molecular; Oligonucleotides; Oxidation-Reduction; Quantum Theory; Rhodium | 2008 |
An ab initio study of substituent effects on the excited states of purine derivatives.
Topics: 2-Aminopurine; Adenine; Electrons; Gases; Guanine; Hypoxanthine; Isomerism; Purines; Quantum Theory; Xanthine | 2008 |
Role of the 2-amino group of purines during dNTP polymerization by human DNA polymerase alpha.
Topics: 2-Aminopurine; Adenine; Base Pairing; Biopolymers; Cytosine; Deoxyribonucleotides; DNA Polymerase I; Humans; Hydrogen Bonding; Kinetics; Purines | 2009 |
Long-range charge transfer through DNA by replacing adenine with diaminopurine.
Topics: 2-Aminopurine; Adenine; DNA; Electron Transport | 2010 |
An integrated molecular dynamics (MD) and experimental study of higher order human telomeric quadruplexes.
Topics: 2-Aminopurine; Adenine; Biophysics; DNA; Humans; Molecular Conformation; Nucleic Acid Conformation; Potassium; Spectrometry, Fluorescence; Spectrophotometry; Static Electricity; Telomere; Temperature; Ultracentrifugation; Ultraviolet Rays | 2010 |
Heterogeneity and dynamics of the ligand recognition mode in purine-sensing riboswitches.
Topics: 2-Aminopurine; Adenine; Aptamers, Nucleotide; Base Pairing; Base Sequence; Binding Sites; Fluorescence Polarization; Guanine; Hydrogen Bonding; Ligands; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; RNA, Catalytic; Spectrometry, Fluorescence; Thermodynamics | 2010 |
Metal ion-binding properties of 9-[(2-phosphonomethoxy)ethyl]-2-aminopurine (PME2AP), an isomer of the antiviral nucleotide analogue 9-[(2-phosphonomethoxy)ethyl]adenine (PMEA). Steric guiding of metal ion-coordination by the purine-amino group.
Topics: 2-Aminopurine; Adenine; Antiviral Agents; Coordination Complexes; Isomerism; Metals; Organophosphonates; Oxygen | 2010 |
Absorption spectroscopy of adenine, 9-methyladenine, and 2-aminopurine in helium nanodroplets.
Topics: 2-Aminopurine; Absorption; Adenine; Chemical Phenomena; Helium; Molecular Structure; Solvents; Spectrum Analysis | 2010 |
Non-B conformations of CAG repeats using 2-aminopurine.
Topics: 2-Aminopurine; Adenine; Base Sequence; DNA; Fragile X Syndrome; Humans; Nucleic Acid Conformation; Thermodynamics; Trinucleotide Repeats | 2011 |
Low-lying excited states and nonradiative processes of the adenine analogues 7H- and 9H-2-aminopurine.
Topics: 2-Aminopurine; Adenine; Algorithms; Electrons; Isomerism; Photons; Quantum Theory; Rotation; Spectrum Analysis; Vibration | 2011 |
Synthesis and antiviral activity of N9-[3-fluoro-2-(phosphonomethoxy)propyl] analogues derived from N6-substituted adenines and 2,6-diaminopurines.
Topics: 2-Aminopurine; 3T3 Cells; Adenine; Animals; Antiviral Agents; Cells, Cultured; Crystallography, X-Ray; Dose-Response Relationship, Drug; HIV-1; HIV-2; Humans; Mice; Mice, Inbred C3H; Moloney murine sarcoma virus; Organophosphonates; Purines; Structure-Activity Relationship | 2011 |
Molecular recognition patterns of 2-aminopurine versus adenine: a view through ternary copper(II) complexes.
Topics: 2-Aminopurine; Adenine; Binding Sites; Chelating Agents; Copper; Cytosine; Imino Acids; Isomerism; Ligands; Models, Molecular; Thymine | 2011 |
Förster resonance energy transfer among a structural isomer of adenine and various Coumarins inside a nanosized reverse micelle.
Topics: 2-Aminopurine; Adenine; Coumarins; Fluorescence Resonance Energy Transfer; Isomerism; Micelles; Nanostructures | 2012 |
Long lifetime of hydrogen-bonded DNA basepairs by force spectroscopy.
Topics: 2-Aminopurine; Adenine; Base Pairing; DNA; Hydrogen Bonding; Kinetics; Spectrum Analysis; Thermodynamics; Thymine; Time Factors | 2012 |
Extent of intramolecular π-stacks in aqueous solution in mixed-ligand copper(II) complexes formed by heteroaromatic amines and several 2-aminopurine derivatives of the antivirally active nucleotide analog 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA).
Topics: 2-Aminopurine; Adenine; Amines; Antiviral Agents; Coordination Complexes; Copper; Drug Stability; Molecular Structure; Solutions; Water | 2012 |
Exciplexes and conical intersections lead to fluorescence quenching in π-stacked dimers of 2-aminopurine with natural purine nucleobases.
Topics: 2-Aminopurine; Adenine; Dimerization; Fluorescence; Guanine; Models, Molecular | 2013 |
Structural destabilization of DNA duplexes containing single-base lesions investigated by nanopore measurements.
Topics: 2-Aminopurine; Adenine; Base Pairing; Cytosine; DNA; Guanidines; Hydantoins; Hydrogen Bonding; Kinetics; Models, Theoretical; Nanopores; Nanotechnology | 2013 |
Dynamics of RNA modification by a multi-site-specific tRNA methyltransferase.
Topics: 2-Aminopurine; Adenine; Archaeal Proteins; Base Sequence; Models, Molecular; Pyrococcus abyssi; RNA, Transfer, Asp; S-Adenosylmethionine; Substrate Specificity; tRNA Methyltransferases | 2014 |
Monitoring translocation of multisubunit RNA polymerase along the DNA with fluorescent base analogues.
Topics: 2-Aminopurine; Adenine; DNA; DNA-Directed RNA Polymerases; Escherichia coli; Fluorescence; Guanine; Molecular Biology; Molecular Structure; Oligonucleotides; Spectrometry, Fluorescence; Transcription, Genetic; Xanthopterin | 2015 |
Molecular recognition between adenine or 2,6-diaminopurine and copper(II) chelates with N,O2,S-tripodal tetradentate chelators having thioether or disulfide donor groups.
Topics: 2-Aminopurine; Adenine; Chelating Agents; Copper; Crystallography, X-Ray; Disulfides; Molecular Structure; Nitrogen; Oxygen; Sulfides; Sulfur | 2015 |
Label-free detection of Phytophthora ramorum using surface-enhanced Raman spectroscopy.
Topics: 2-Aminopurine; Adenine; DNA; Metal Nanoparticles; Microscopy, Electron, Scanning; Nanotechnology; Nucleic Acid Hybridization; Phytophthora; Plant Leaves; Rhododendron; Scattering, Radiation; Silver; Spectrum Analysis, Raman; Surface Properties | 2015 |
Continuous Fluorescence Assays for Reactions Involving Adenine.
Topics: 2-Aminopurine; Adenine; Adenine Phosphoribosyltransferase; Enzyme Assays; Fluorescence; Humans; Kinetics; Saccharomyces cerevisiae; Substrate Specificity | 2016 |
On the origin of multiexponential fluorescence decays from 2-aminopurine-labeled dinucleotides.
Topics: 2-Aminopurine; Adenine; Fluorescence; Kinetics; Nucleic Acid Conformation; Nucleotides | 2016 |
A triple exon-skipping luciferase reporter assay identifies a new CLK inhibitor pharmacophore.
Topics: 2-Aminopurine; Adenine; Binding Sites; Cyclin-Dependent Kinases; Exons; Genes, Reporter; High-Throughput Screening Assays; Humans; Inhibitory Concentration 50; Luciferases; Molecular Dynamics Simulation; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; RNA Splicing; Structure-Activity Relationship | 2017 |
Ultrafast structural dynamics of photoexcited adenine.
Topics: 2-Aminopurine; Adenine; Guanine; Quantum Theory; Spectrum Analysis, Raman; Ultraviolet Rays | 2017 |
DNA nanodevices monitored with fluorogenic looped-out 2-aminopurine.
Topics: 2-Aminopurine; Adenine; Base Pairing; DNA; G-Quadruplexes; Nanotechnology; Nucleic Acid Conformation | 2018 |
Purine-Derived Nitroxides for Noncovalent Spin-Labeling of Abasic Sites in Duplex Nucleic Acids.
Topics: 2-Aminopurine; Adenine; Cyclic N-Oxides; Cytosine; DNA; Guanine; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acids; Purines; RNA; Spin Labels; Thymine | 2018 |
Base-Pairing Properties of Double-Headed Nucleotides.
Topics: 2-Aminopurine; Adenine; Base Pair Mismatch; Base Pairing; Cytosine; DNA; Guanine; Hypoxanthine; Models, Molecular; Nucleic Acid Conformation; Nucleotides; Thymine | 2019 |
DNA-like Photophysics in Self-Assembled Silver(I)-Nucleobase Nanofibers.
Topics: 2-Aminopurine; Adenine; DNA; Nanofibers; Silver Nitrate; Water | 2019 |
How cyanophage S-2L rejects adenine and incorporates 2-aminoadenine to saturate hydrogen bonding in its DNA.
Topics: 2-Aminopurine; Adenine; Bacteriophages; Binding Sites; Biocatalysis; Cyanobacteria; DNA Primase; DNA-Directed DNA Polymerase; DNA, Viral; Hydrogen Bonding; Models, Molecular; Molecular Structure; Protein Domains; Synechococcus; Viral Proteins | 2021 |
2,6-diaminopurine promotes repair of DNA lesions under prebiotic conditions.
Topics: 2-Aminopurine; Adenine; DNA; DNA Repair; Molecular Dynamics Simulation; Nucleic Acids; Nucleotides; Pyrimidine Dimers; RNA; Ultraviolet Rays | 2021 |
A Chemical Approach to Introduce 2,6-Diaminopurine and 2-Aminoadenine Conjugates into Oligonucleotides without Need for Protecting Groups.
Topics: 2-Aminopurine; Adenine; Oligonucleotides | 2022 |