adenine and 2'-deoxyadenosine triphosphate

adenine has been researched along with 2'-deoxyadenosine triphosphate in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19902 (12.50)18.7374
1990's6 (37.50)18.2507
2000's3 (18.75)29.6817
2010's5 (31.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bianchi, V; Pontis, E; Reichard, P1
Beattie, KL; Revich, GG1
Fairbanks, LD; Goday, A; Morris, GS; Simmonds, HA1
Volkov, VS1
Aquaro, S; Balestra, E; Balzarini, J; Calio, R; Cenci, A; Di Pierro, D; Lazzarino, G; Panti, S; Perno, CF; Tavazzi, B1
Johnson, KA; Suo, Z1
Balzarini, J; De Clercq, E; Hatse, S; Naesens, L1
Downey, KM; Kramata, P1
Bartholomew, B; Zofall, M1
Fridland, A; Olson, L; Ray, AS; Vela, JE1
Chi, LM; Lam, SL1
Babusis, D; Durand-Gasselin, L; Flaherty, JF; Hawkins, T; Ray, AS; Reddy, YS; Veikley, W1
Aung, W; Cong, ME; García-Lerma, JG; Hanson, DL; Heneine, W; Holder, A; Kersh, E; Kuklenyik, S; Lee, WA; Lin, CY; Luo, W; Martin, A; Mitchell, J; Pau, CP; Ray, AS; Rooney, JF; Youngpairoj, AS; Zheng, Q1
Kaur, P; Kushwaha, GS; Pandey, N; Sharma, S; Singh, SB; Singh, TP; Sinha, M1
Anderson, KS; Becnel, KD; Frey, KM; Garforth, SJ; Kim, J; Li, Y; Liotta, DC; Prasad, VR; Schinazi, RF; Wang, L1
Cafarelli, TM; Godoy, VG; Rands, TJ1

Trials

1 trial(s) available for adenine and 2'-deoxyadenosine triphosphate

ArticleYear
Intracellular nucleotide levels during coadministration of tenofovir disoproxil fumarate and didanosine in HIV-1-infected patients.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:4

    Topics: Adenine; Adult; Aged; Anti-HIV Agents; Chromatography, Liquid; Deoxyadenine Nucleotides; Deoxyguanine Nucleotides; Didanosine; Dideoxynucleotides; Female; HIV Infections; Humans; Male; Middle Aged; Nucleotides; Organophosphonates; Tandem Mass Spectrometry; Tenofovir; Young Adult

2011

Other Studies

15 other study(ies) available for adenine and 2'-deoxyadenosine triphosphate

ArticleYear
Dynamics of the dATP pool in cultured mammalian cells.
    Experimental cell research, 1992, Volume: 199, Issue:1

    Topics: 3T3 Cells; Adenine; Animals; Aphidicolin; Cell Line; Cytarabine; Deoxyadenine Nucleotides; Deoxyadenosines; DNA; Hypoxanthine; Hypoxanthines; Kinetics; Mice; Pentostatin; Substrate Cycling; Thymine Nucleotides

1992
Utilization of 1,N6-etheno-2'-deoxyadenosine 5'-triphosphate during DNA synthesis on natural templates, catalyzed by DNA polymerase I of Escherichia coli.
    Carcinogenesis, 1986, Volume: 7, Issue:9

    Topics: Adenine; Adenosine Triphosphate; Base Composition; Deoxyadenine Nucleotides; Deoxyribonucleotides; DNA; DNA Polymerase I; Escherichia coli; Ethenoadenosine Triphosphate; Templates, Genetic

1986
B cells as well as T cells form deoxynucleotides from either deoxyadenosine or deoxyguanosine.
    Clinical and experimental immunology, 1984, Volume: 56, Issue:1

    Topics: Adenine; Adenosine Deaminase Inhibitors; B-Lymphocytes; Cell Line; Cell Survival; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; Deoxyguanine Nucleotides; Deoxyguanosine; Dose-Response Relationship, Drug; Guanosine; Humans; Pentostatin; Purine-Nucleoside Phosphorylase; T-Lymphocytes

1984
[Interaction of formaldehyde with nucleic acids and their structural components in the presence of amines. V. Isotopic exchange of hydrogen 3H---1H at the C8 atom of dATP, adenosine, adenine, guanosine, and poly(A)].
    Biokhimiia (Moscow, Russia), 1994, Volume: 59, Issue:8

    Topics: Adenine; Adenosine; Amines; Amino Acid Sequence; Deoxyadenine Nucleotides; Formaldehyde; Guanosine; Hydrogen; Isotopes; Kinetics; Molecular Sequence Data; Nucleic Acids; Poly A

1994
Potent inhibition of human immunodeficiency virus and herpes simplex virus type 1 by 9-(2-phosphonylmethoxyethyl)adenine in primary macrophages is determined by drug metabolism, nucleotide pools, and cytokines.
    Molecular pharmacology, 1996, Volume: 50, Issue:2

    Topics: Adenine; Animals; Antiviral Agents; Chlorocebus aethiops; Deoxyadenine Nucleotides; Granulocyte-Macrophage Colony-Stimulating Factor; Herpesvirus 1, Human; HIV; Humans; Macrophage Colony-Stimulating Factor; Macrophages; Organophosphonates; Vero Cells

1996
Selective inhibition of HIV-1 reverse transcriptase by an antiviral inhibitor, (R)-9-(2-Phosphonylmethoxypropyl)adenine.
    The Journal of biological chemistry, 1998, Oct-16, Volume: 273, Issue:42

    Topics: Adenine; Animals; Anti-HIV Agents; Deoxyadenine Nucleotides; Dideoxynucleotides; DNA Polymerase beta; HIV Reverse Transcriptase; Kinetics; Models, Chemical; Organophosphonates; Organophosphorus Compounds; Rats; Reverse Transcriptase Inhibitors; RNA, Viral; Tenofovir

1998
N6-cyclopropyl-PMEDAP: a novel derivative of 9-(2-phosphonylmethoxyethyl)-2,6-diaminopurine (PMEDAP) with distinct metabolic, antiproliferative, and differentiation-inducing properties.
    Biochemical pharmacology, 1999, Jul-15, Volume: 58, Issue:2

    Topics: Adenine; Adenosine Deaminase; Adenosine Triphosphate; AMP Deaminase; Animals; Antineoplastic Agents; Cell Cycle; Cell Differentiation; Cell Division; Deoxyadenine Nucleotides; Drug Interactions; Drug Screening Assays, Antitumor; Erythrocytes; Guanine; Humans; K562 Cells; Leukemia L1210; Mice; Organophosphonates; Organophosphorus Compounds; Pentostatin; Prodrugs; Rats; Tumor Cells, Cultured

1999
9-(2-phosphonylmethoxyethyl) derivatives of purine nucleotide analogs: A comparison of their metabolism and interaction with cellular DNA synthesis.
    Molecular pharmacology, 1999, Volume: 56, Issue:6

    Topics: Adenine; Antineoplastic Agents; Deoxyadenine Nucleotides; DNA; DNA Polymerase I; DNA Polymerase II; DNA Polymerase III; Guanine; Humans; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Tumor Cells, Cultured

1999
Two novel dATP analogs for DNA photoaffinity labeling.
    Nucleic acids research, 2000, Nov-01, Volume: 28, Issue:21

    Topics: Adenine; Adenosine Monophosphate; Azides; Base Sequence; Chromatography, Thin Layer; Deoxyadenine Nucleotides; Deoxyadenosines; Diphosphates; DNA; DNA Polymerase I; DNA-Binding Proteins; Indicators and Reagents; Phosphorylation; Photoaffinity Labels

2000
Effective metabolism and long intracellular half life of the anti-hepatitis B agent adefovir in hepatic cells.
    Biochemical pharmacology, 2004, Nov-01, Volume: 68, Issue:9

    Topics: Adenine; Animals; Antiviral Agents; Biological Transport; Cells, Cultured; Deoxyadenine Nucleotides; Half-Life; Hepatitis B virus; Hepatocytes; Humans; Organophosphonates; Phosphorylation

2004
Nuclear magnetic resonance investigation of primer--template models: formation of a pyrimidine bulge upon misincorporation.
    Biochemistry, 2008, Apr-15, Volume: 47, Issue:15

    Topics: Adenine; Base Pair Mismatch; Base Pairing; Cytosine; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; DNA Primers; DNA Replication; Guanine; Models, Genetic; Nuclear Magnetic Resonance, Biomolecular; Templates, Genetic; Thymidine; Thymine Nucleotides

2008
Natural substrate concentrations can modulate the prophylactic efficacy of nucleotide HIV reverse transcriptase inhibitors.
    Journal of virology, 2011, Volume: 85, Issue:13

    Topics: Adenine; Animals; Anti-HIV Agents; Chemoprevention; Deoxyadenine Nucleotides; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lymphocytes; Lymphoid Tissue; Macaca; Organophosphonates; Prodrugs; Rectum; Reverse Transcriptase Inhibitors; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Substrate Specificity; Tenofovir

2011
Crystal structures of a type-1 ribosome inactivating protein from Momordica balsamina in the bound and unbound states.
    Biochimica et biophysica acta, 2012, Volume: 1824, Issue:4

    Topics: Adenine; Adenosine Triphosphate; Amino Acid Sequence; Animals; Catalytic Domain; Conserved Sequence; Crystallography, X-Ray; Deoxyadenine Nucleotides; Guanine; Hydrobromic Acid; Models, Molecular; Molecular Sequence Data; Momordica; Plant Proteins; Protein Binding; Protein Structure, Secondary; Rats; Ribose; Ribosome Inactivating Proteins, Type 1; Ribosomes; RNA, Bacterial; RNA, Ribosomal; Structural Homology, Protein

2012
Pre-steady state kinetic analysis of cyclobutyl derivatives of 2'-deoxyadenosine 5'-triphosphate as inhibitors of HIV-1 reverse transcriptase.
    Bioorganic & medicinal chemistry letters, 2012, Jun-15, Volume: 22, Issue:12

    Topics: Adenine; Anti-HIV Agents; Cyclobutanes; Deoxyadenine Nucleotides; DNA Primers; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Kinetics; Mutation; Nucleic Acid Amplification Techniques; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir

2012
The DinB•RecA complex of Escherichia coli mediates an efficient and high-fidelity response to ubiquitous alkylation lesions.
    Environmental and molecular mutagenesis, 2014, Volume: 55, Issue:2

    Topics: Adenine; Alkylation; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA Adducts; DNA Replication; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Kinetics; Mutagenesis; Rec A Recombinases; Thymine Nucleotides

2014