adefovir has been researched along with p-aminohippuric acid in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cihlar, T; Fuller, MD; Lin, DC; Mendel, DB; Pritchard, JB; Sweet, DH | 1 |
| Cihlar, T; Ho, ES; Lin, DC; Mendel, DB | 1 |
| Cihlar, T; Ho, ES | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brett, CM; Brown, C; Burchard, EG; Carlson, EJ; Castro, R; Chen, CW; de la Cruz, M; Ferrin, TE; Fujita, K; Fujita, T; Giacomini, KM; Huang, CC; Johns, SJ; Kawamoto, M; Leabman, MK; Lin, ET; Stryke, D; Taylor, T | 1 |
| Bleasby, K; Hall, LA; Mohrenweiser, HW; Perry, JL; Pritchard, JB | 1 |
| Fujita, T; Horita, S; Ikeda, Y; Kondo, T; Kumagai, Y; Kusuhara, H; Maeda, K; Nakayama, H; Sugiyama, Y; Tanabe, K; Tian, Y | 1 |
2 review(s) available for adefovir and p-aminohippuric acid
| Article | Year |
|---|---|
Membrane transporters in drug development.
Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs | 2010 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for adefovir and p-aminohippuric acid
| Article | Year |
|---|---|
Inhibitory effects of p-aminohippurate and probenecid on the renal clearance of adefovir and benzylpenicillin as probe drugs for organic anion transporter (OAT) 1 and OAT3 in humans.
Topics: Adenine; Adult; Drug Interactions; HEK293 Cells; Humans; In Vitro Techniques; Kidney; Male; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Organophosphonates; p-Aminohippuric Acid; Penicillin G; Probenecid; Young Adult | 2014 |
6 other study(ies) available for adefovir and p-aminohippuric acid
| Article | Year |
|---|---|
The antiviral nucleotide analogs cidofovir and adefovir are novel substrates for human and rat renal organic anion transporter 1.
Topics: Adenine; Amino Acid Sequence; Animals; Anion Transport Proteins; Antiviral Agents; Base Sequence; Biological Transport; Carrier Proteins; Cidofovir; Cloning, Molecular; Cytosine; DNA, Complementary; Humans; Immunoblotting; Kidney; Molecular Sequence Data; Nucleosides; Organophosphonates; Organophosphorus Compounds; Rats | 1999 |
Cytotoxicity of antiviral nucleotides adefovir and cidofovir is induced by the expression of human renal organic anion transporter 1.
Topics: Adenine; Alanine; Animals; Anion Transport Proteins; Antiviral Agents; Biological Transport; Carrier Proteins; CHO Cells; Cidofovir; Cricetinae; Cytosine; Humans; Kidney; Organophosphate Poisoning; Organophosphonates; Organophosphorus Compounds; Probenecid | 2000 |
Fluorescence-based assay for the interaction of small molecules with the human renal organic anion transporter 1.
Topics: Animals; Anion Transport Proteins; Anions; Arylsulfonates; Boron Compounds; Carrier Proteins; CHO Cells; Cricetinae; DNA, Complementary; Dose-Response Relationship, Drug; Fluorescein; Fluoresceins; Fluorescent Dyes; Glutarates; Humans; Inhibitory Concentration 50; Kinetics; Models, Chemical; Spectrometry, Fluorescence; Time Factors; Transfection | 2000 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Functional analysis of polymorphisms in the organic anion transporter, SLC22A6 (OAT1).
Topics: Adenine; Adult; Animals; Anions; Antineoplastic Agents; DNA, Complementary; Genetic Variation; Genotype; Haplotypes; Heterozygote; Humans; Kidney; Kinetics; Male; Methotrexate; Models, Chemical; Models, Genetic; Mycotoxins; Ochratoxins; Organic Anion Transport Protein 1; Organic Anion Transporters; Organophosphonates; p-Aminohippuric Acid; Pedigree; Pharmacogenetics; Polymorphism, Genetic; Protein Structure, Secondary; RNA, Complementary; Xenobiotics; Xenopus laevis | 2005 |
Functional consequences of single nucleotide polymorphisms in the human organic anion transporter hOAT1 (SLC22A6).
Topics: Adenine; Amino Acid Sequence; Animals; Antiviral Agents; Cidofovir; Cytosine; DNA; Genetic Variation; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Organic Anion Transport Protein 1; Organophosphonates; p-Aminohippuric Acid; Polymorphism, Single Nucleotide; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Complementary; Tenofovir; Xenopus laevis | 2005 |