adefovir has been researched along with methotrexate in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 6 (46.15) | 29.6817 |
| 2010's | 5 (38.46) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Balzarini, J; De Clercq, E; Degrève, B; Hatse, S; Naesens, L; Vandeputte, M; Waer, M | 1 |
| Balzarini, J; De Clercq, E; Hatse, S; Naesens, L | 1 |
| Ambudkar, SV; Nandigama, K; Sauna, ZE | 1 |
| Brett, CM; Brown, C; Burchard, EG; Carlson, EJ; Castro, R; Chen, CW; de la Cruz, M; Ferrin, TE; Fujita, K; Fujita, T; Giacomini, KM; Huang, CC; Johns, SJ; Kawamoto, M; Leabman, MK; Lin, ET; Stryke, D; Taylor, T | 1 |
| Di Martino, V; Herbein, G; Prati, C; Toussirot, E; Wendling, D | 1 |
| Ambudkar, SV; Cheepala, SB; Ekins, S; Fukuda, Y; Schuetz, JD; Sparreboom, A; Takenaka, K; Wu, CP | 1 |
2 review(s) available for adefovir and methotrexate
| Article | Year |
|---|---|
Membrane transporters in drug development.
Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs | 2010 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
11 other study(ies) available for adefovir and methotrexate
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
In vitro and in vivo inhibitory activity of the differentiation-inducing agent 9-(2-phosphonylmethoxyethyl)adenine (PMEA) against rat choriocarcinoma.
Topics: Adenine; Alkaline Phosphatase; Animals; Antineoplastic Agents; Cell Differentiation; Cell Division; Choriocarcinoma; Methotrexate; Organophosphonates; Progesterone; Rats; Rats, Inbred Strains; Stereoisomerism | 1998 |
Potent differentiation-inducing properties of the antiretroviral agent 9-(2-phosphonylmethoxyethyl) adenine (PMEA) in the rat choriocarcinoma (RCHO) tumor cell model.
Topics: Adenine; Alkaline Phosphatase; Animals; Antigens, Neoplasm; Antigens, Surface; Antiviral Agents; Cell Differentiation; Cell Survival; Choriocarcinoma; Drug Therapy, Combination; Enzyme Induction; Growth Inhibitors; Kidney Neoplasms; Methotrexate; Organophosphonates; Organophosphorus Compounds; Progesterone; Rats; Rats, Inbred Strains; Rats, Wistar; Retroviridae; Tenofovir; Trophoblasts; Tumor Cells, Cultured | 1998 |
Multidrug resistance protein 4 (ABCC4)-mediated ATP hydrolysis: effect of transport substrates and characterization of the post-hydrolysis transition state.
Topics: Adenine; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Beryllium; Biological Transport; Catalysis; Cations; Cell Line; Cell Membrane; Chelating Agents; Cobalt; Dinoprostone; DNA, Complementary; Dose-Response Relationship, Drug; Edetic Acid; Fluorides; Humans; Hydrolysis; Insecta; Kinetics; Magnesium; Manganese; Methotrexate; Models, Biological; Multidrug Resistance-Associated Proteins; Nucleotides; Organophosphonates; Protein Binding; Substrate Specificity; Vanadates; Zidovudine | 2004 |
Functional analysis of polymorphisms in the organic anion transporter, SLC22A6 (OAT1).
Topics: Adenine; Adult; Animals; Anions; Antineoplastic Agents; DNA, Complementary; Genetic Variation; Genotype; Haplotypes; Heterozygote; Humans; Kidney; Kinetics; Male; Methotrexate; Models, Chemical; Models, Genetic; Mycotoxins; Ochratoxins; Organic Anion Transport Protein 1; Organic Anion Transporters; Organophosphonates; p-Aminohippuric Acid; Pedigree; Pharmacogenetics; Polymorphism, Genetic; Protein Structure, Secondary; RNA, Complementary; Xenobiotics; Xenopus laevis | 2005 |
Spondyloarthropathy and chronic B hepatitis. Effect of anti-TNF therapy.
Topics: Adenine; Adult; Antibodies, Monoclonal; Antirheumatic Agents; Antiviral Agents; Drug Therapy, Combination; Etanercept; Female; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immunocompromised Host; Immunoglobulin G; Infliximab; Lamivudine; Male; Methotrexate; Organophosphonates; Receptors, Tumor Necrosis Factor; Spondylarthropathies; Treatment Outcome; Tumor Necrosis Factor-alpha; Viral Load; Virus Activation | 2009 |
Human immunodeficiency virus protease inhibitors interact with ATP binding cassette transporter 4/multidrug resistance protein 4: a basis for unanticipated enhanced cytotoxicity.
Topics: Adenine; Animals; Antineoplastic Agents; Cell Line; Cell Line, Tumor; Cell Proliferation; Drug Interactions; Female; HIV Protease Inhibitors; Humans; Hydrolysis; Methotrexate; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Molecular; Multidrug Resistance-Associated Proteins; Nelfinavir; Organophosphonates; Ritonavir | 2013 |