Compounds > adefovir
Page last updated: 2024-08-24

adefovir and ganciclovir

adefovir has been researched along with ganciclovir in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (15.79)18.2507
2000's8 (42.11)29.6817
2010's7 (36.84)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Alam, M; Brankovan, V; Bronson, JJ; Datema, R; Hitchcock, MJ; Martin, JC; Patick, A; Yang, H; Yu, KL1
Bisagni, E; Boumchita, H; Huel, C; Legraverend, M; Lemaitre, M; Zerial, A1
Alvarez, K; Balzarini, J; Barral, K; Canard, B; Neyts, J; Priet, S; Sire, J1
Lombardo, F; Obach, RS; Waters, NJ1
Andrei, G; Balzarini, J; Camarasa, MJ; de Castro, S; Naesens, L; Peromingo, MT; Snoeck, R; Velázquez, S1
Chou, KC; González-Díaz, H; Martinez de la Vega, O; Prado-Prado, FJ; Ubeira, FM; Uriarte, E1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Agrofoglio, LA; Alexandre, JA; Andrei, G; Azzouzi, A; Balzarini, J; Broggi, J; Caillat, C; Deville-Bonne, D; El-Amri, C; Eriksson, S; Lin, J; Meyer, P; Pradère, U; Roy, V; Snoeck, R; Topalis, D1
Andrei, G; Balzarini, J; Dračínský, M; Holý, A; Krečmerová, M; Snoeck, R; Tichý, T1
Andrei, G; Balzarini, J; Hocková, D; Holý, A; Snoeck, R1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
De Castro, LM; De Clercq, E; Gangemi, JD; Ghaffar, A; Kern, ER; Mayer, EP; Vogt, PE1
de Man, RA; Niesters, HG; Wolters, LM1
Morton, CJ; Ng, HL; Parker, MW; Rawlinson, WD; Scott, GM1
Croubels, S; De Backer, P; Garré, B; Nauwynck, H; Neyts, J; Nugent, J; van der Meulen, K1
Razonable, RR1

Reviews

3 review(s) available for adefovir and ganciclovir

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Nucleoside analogues for chronic hepatitis B.
    European journal of gastroenterology & hepatology, 2001, Volume: 13, Issue:12

    Topics: 2-Aminopurine; Adenine; Antiviral Agents; Famciclovir; Ganciclovir; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates; Reverse Transcriptase Inhibitors

2001
Antiviral drugs for viruses other than human immunodeficiency virus.
    Mayo Clinic proceedings, 2011, Volume: 86, Issue:10

    Topics: Acyclovir; Adenine; Amantadine; Antiviral Agents; Comorbidity; Drug Therapy, Combination; Foscarnet; Ganciclovir; Guanine; Hepatitis; Hepatitis B, Chronic; Hepatitis C; Herpesviridae Infections; HIV Infections; Humans; Influenza, Human; Interferons; Lamivudine; Nucleosides; Oligopeptides; Organophosphonates; Oseltamivir; Proline; Protease Inhibitors; Pyrimidinones; Ribavirin; Telbivudine; Thymidine; Valacyclovir; Valganciclovir; Valine; Virus Replication; Zanamivir

2011

Other Studies

16 other study(ies) available for adefovir and ganciclovir

ArticleYear
Synthesis and antiviral activity of methyl derivatives of 9-[2-(phosphonomethoxy)ethyl]guanine.
    Journal of medicinal chemistry, 1992, Aug-07, Volume: 35, Issue:16

    Topics: Antiviral Agents; Cell Line; Guanine; HIV; Microbial Sensitivity Tests; Organophosphorus Compounds; Simplexvirus; Stereoisomerism; Structure-Activity Relationship

1992
Synthesis of new (+-)-3,5-dihydroxypentyl nucleoside analogues from 1-amino-5-(benzyloxy)pentan-3-ol and their antiviral evaluation.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:9

    Topics: Amino Alcohols; Antiviral Agents; Cell Line; Chemical Phenomena; Chemistry; Humans; Microbial Sensitivity Tests; Nucleosides; Pentanols; Structure-Activity Relationship

1990
Synthesis, in vitro antiviral evaluation, and stability studies of novel alpha-borano-nucleotide analogues of 9-[2-(phosphonomethoxy)ethyl]adenine and (R)-9-[2-(phosphonomethoxy)propyl]adenine.
    Journal of medicinal chemistry, 2006, Dec-28, Volume: 49, Issue:26

    Topics: Adenine; Animals; Anti-HIV Agents; Antiviral Agents; Boranes; Boron Compounds; Chlorocebus aethiops; DNA Viruses; HIV-1; Humans; In Vitro Techniques; Nucleosides; Organophosphonates; Phosphates; RNA Viruses; Structure-Activity Relationship; Vero Cells; Virus Replication

2006
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
4"-Benzoylureido-TSAO derivatives as potent and selective non-nucleoside HCMV inhibitors. Structure-activity relationship and mechanism of antiviral action.
    Journal of medicinal chemistry, 2008, Sep-25, Volume: 51, Issue:18

    Topics: Antiviral Agents; Cell Line; Cytomegalovirus; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Thymidine; Urea

2008
Unified QSAR approach to antimicrobials. 4. Multi-target QSAR modeling and comparative multi-distance study of the giant components of antiviral drug-drug complex networks.
    Bioorganic & medicinal chemistry, 2009, Jan-15, Volume: 17, Issue:2

    Topics: Anti-Infective Agents; Antiviral Agents; Artificial Intelligence; Computer Simulation; Drug Evaluation, Preclinical; Molecular Structure; Quantitative Structure-Activity Relationship

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
Novel antiviral C5-substituted pyrimidine acyclic nucleoside phosphonates selected as human thymidylate kinase substrates.
    Journal of medicinal chemistry, 2011, Jan-13, Volume: 54, Issue:1

    Topics: Antiviral Agents; Catalytic Domain; Cells, Cultured; Crystallography, X-Ray; Herpesviridae; Humans; Ligands; Models, Molecular; Molecular Structure; Nucleoside-Phosphate Kinase; Organophosphonates; Prodrugs; Pyrimidine Nucleosides; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity; Thymidine; Thymidine Kinase

2011
New prodrugs of Adefovir and Cidofovir.
    Bioorganic & medicinal chemistry, 2011, Jun-01, Volume: 19, Issue:11

    Topics: Adenine; Animals; Antiviral Agents; Cell Line, Tumor; Cidofovir; Cytomegalovirus; Cytosine; Herpesvirus 3, Human; HIV; Humans; Organophosphonates; Prodrugs; Simplexvirus

2011
Acyclic nucleoside phosphonates with a branched 2-(2-phosphonoethoxy)ethyl chain: efficient synthesis and antiviral activity.
    Bioorganic & medicinal chemistry, 2011, Aug-01, Volume: 19, Issue:15

    Topics: Animals; Antiviral Agents; Cell Line; Cell Survival; Herpes Simplex; HIV; HIV Infections; Humans; Mice; Nucleosides; Organophosphonates; Simplexvirus; Structure-Activity Relationship; Vaccinia; Vaccinia virus; Virus Diseases; Viruses

2011
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Phosphonylmethoxyalkyl purine and pyrimidine derivatives for treatment of opportunistic cytomegalovirus and herpes simplex virus infections in murine AIDS.
    Antiviral research, 1991, Volume: 16, Issue:1

    Topics: Adenine; Animals; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Ganciclovir; Herpes Simplex; Immune Tolerance; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; Opportunistic Infections; Organophosphonates; Organophosphorus Compounds

1991
Murine cytomegalovirus resistant to antivirals has genetic correlates with human cytomegalovirus.
    The Journal of general virology, 2005, Volume: 86, Issue:Pt 8

    Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Ganciclovir; Guanine; Humans; Mice; Models, Molecular; Molecular Sequence Data; Muromegalovirus; Mutation; Organophosphonates; Protein Kinases; Sequence Alignment; Valacyclovir; Valine; Virus Replication

2005
In vitro susceptibility of six isolates of equine herpesvirus 1 to acyclovir, ganciclovir, cidofovir, adefovir, PMEDAP and foscarnet.
    Veterinary microbiology, 2007, May-16, Volume: 122, Issue:1-2

    Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Cell Survival; Cells, Cultured; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Drug Resistance, Viral; Epithelial Cells; Foscarnet; Ganciclovir; Herpesvirus 1, Equid; Horses; Lung; Organophosphonates

2007