adefovir has been researched along with 9-((2-phosphonylmethoxy)ethyl)guanine in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (76.92) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alam, M; Brankovan, V; Bronson, JJ; Datema, R; Hitchcock, MJ; Martin, JC; Patick, A; Yang, H; Yu, KL | 1 |
| Bronson, JJ; Ghazzouli, I; Hitchcock, MJ; Kim, CU; Luh, BY; Martin, JC; Misco, PF | 1 |
| Andrei, G; Balzarini, J; De Clercq, E; Dvoráková, H; Günter, J; Holý, A; Masojídková, M; Snoeck, R | 1 |
| Cihlar, T; Fuller, MD; Lin, DC; Mendel, DB; Pritchard, JB; Sweet, DH | 1 |
| Davari, H; Hakimelahi, GH; Hakimelahi, S; Jain, ML; Ly, TW; Mei, HC; Moosavi-Movahedi, AA; Moshfegh, AA; Sambaiah, T; Zakerinia, M | 1 |
| Cordeiro, MN; Fernández, F; García-Mera, X; Helguera, AM; Rodríguez-Borges, JE | 1 |
| Andrei, G; Crance, JM; De Clercq, E; De Vos, R; Duraffour, S; Garin, D; Holy, A; Krecmerová, M; Snoeck, R; van Den Oord, J | 1 |
| Holý, A; Merta, A; Stĕtina, R; Votruba, I | 1 |
| Balzarini, J; Casara, P; De Clercq, E; Egberink, H; Hartmann, K; Navé, JF; Pannecouque, C; Vahlenkamp, T; Witvrouw, M | 1 |
| Connelly, MC; Fridland, A; Lee, SH; Pisarev, VM | 1 |
| Balzarini, J; De Clercq, E; Hatse, S; Naesens, L | 1 |
| Bílá, V; Holý, A; Lesková, V; Mejsnarová, B; Otová, B; Sladká, M; Votruba, I | 1 |
| Downey, KM; Kramata, P | 1 |
13 other study(ies) available for adefovir and 9-((2-phosphonylmethoxy)ethyl)guanine
| Article | Year |
|---|---|
Synthesis and antiviral activity of methyl derivatives of 9-[2-(phosphonomethoxy)ethyl]guanine.
Topics: Antiviral Agents; Cell Line; Guanine; HIV; Microbial Sensitivity Tests; Organophosphorus Compounds; Simplexvirus; Stereoisomerism; Structure-Activity Relationship | 1992 |
Acyclic purine phosphonate analogues as antiviral agents. Synthesis and structure-activity relationships.
Topics: Antiviral Agents; Chemical Phenomena; Chemistry; Kinetics; Organophosphonates; Purines; Retroviridae; Simplexvirus; Structure-Activity Relationship | 1990 |
Structure-antiviral activity relationship in the series of pyrimidine and purine N-[2-(2-phosphonomethoxy)ethyl] nucleotide analogues. 1. Derivatives substituted at the carbon atoms of the base.
Topics: Animals; Anti-HIV Agents; Antiviral Agents; Cell Line; DNA Viruses; HIV-1; HIV-2; Humans; Moloney murine sarcoma virus; Organophosphonates; Purine Nucleotides; Pyrimidine Nucleotides; Structure-Activity Relationship | 1999 |
The antiviral nucleotide analogs cidofovir and adefovir are novel substrates for human and rat renal organic anion transporter 1.
Topics: Adenine; Amino Acid Sequence; Animals; Anion Transport Proteins; Antiviral Agents; Base Sequence; Biological Transport; Carrier Proteins; Cidofovir; Cloning, Molecular; Cytosine; DNA, Complementary; Humans; Immunoblotting; Kidney; Molecular Sequence Data; Nucleosides; Organophosphonates; Organophosphorus Compounds; Rats | 1999 |
Design, synthesis, and biological evaluation of novel nucleoside and nucleotide analogues as agents against DNA viruses and/or retroviruses.
Topics: Adenine; Adenine Nucleotides; Adenosine Deaminase Inhibitors; Animals; Antineoplastic Agents; Antiviral Agents; Cell Line; Chlorocebus aethiops; DNA Viruses; Drug Design; Enzyme Inhibitors; Lethal Dose 50; Leukemia, Experimental; Mice; Nucleosides; Nucleotides; Phosphoric Diester Hydrolases; Phosphorylation; Retroviridae; Retroviridae Infections; Simplexvirus; Snake Venoms; Spleen; Thymidine Kinase; Tumor Virus Infections; Vero Cells | 2001 |
Probing the anticancer activity of nucleoside analogues: a QSAR model approach using an internally consistent training set.
Topics: Algorithms; Antineoplastic Agents; Databases, Factual; Discriminant Analysis; Models, Molecular; Nucleosides; Quantitative Structure-Activity Relationship | 2007 |
Activities of several classes of acyclic nucleoside phosphonates against camelpox virus replication in different cell culture models.
Topics: Adenine; Animals; Antiviral Agents; Cell Line; Cells, Cultured; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Humans; Infant, Newborn; Male; Mice; Microscopy, Electron, Transmission; Nucleosides; Organophosphonates; Organophosphorus Compounds; Orthopoxvirus; Swiss 3T3 Cells; Virus Replication | 2007 |
The effect of purine phosphonomethoxyalkyl derivatives on DNA synthesis in CHO Chinese hamster cells.
Topics: Adenine; Animals; Antiviral Agents; CHO Cells; Cricetinae; Cricetulus; Cytarabine; DNA Damage; DNA Replication; Dose-Response Relationship, Drug; Guanine; Organophosphonates; Organophosphorus Compounds; Zidovudine | 1993 |
Antiretroviral activities of acyclic nucleoside phosphonates [9-(2-phosphonylmethoxyethyl)adenine, 9-(2-phosphonylmethoxyethyl)guanine, (R)-9-(2-phosphonylmethoxypropyl)adenine, and MDL 74,968] in cell cultures and murine sarcoma virus-infected newborn NM
Topics: Adenine; Animals; Animals, Newborn; Antiviral Agents; Cell Line; Fibroblasts; Guanine; Humans; Mice; Mice, Inbred C3H; Organophosphonates; Organophosphorus Compounds; Retroviridae; Retroviridae Infections; Sarcoma Viruses, Murine; Tenofovir | 1997 |
Intracellular metabolism and action of acyclic nucleoside phosphonates on DNA replication.
Topics: Adenine; Antineoplastic Agents; Cell Line; DNA Replication; DNA-Directed DNA Polymerase; Guanine; Humans; Organophosphonates; Organophosphorus Compounds; Simian virus 40; Tenofovir | 1997 |
Selection and characterisation of murine leukaemia L1210 cells with high-level resistance to the cytostatic activity of the acyclic nucleoside phosphonate 9-(2-phosphonylmethoxyethyl) adenine (PMEA).
Topics: Adenine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antineoplastic Agents; Biological Transport; Biotransformation; Cell Survival; Cyclic AMP; Drug Resistance, Neoplasm; Guanine; Kinetics; Leukemia L1210; Mice; Organophosphonates; Organophosphorus Compounds; Purine Nucleotides; Structure-Activity Relationship; Tumor Cells, Cultured | 1998 |
Genotoxicity of purine acyclic nucleotide analogs.
Topics: Adenine; Animals; Antiviral Agents; Cell Line; Female; Guanine; Humans; Male; Molecular Structure; Mutagenicity Tests; Mutagens; Organophosphonates; Organophosphorus Compounds; Purines; Rats; Rats, Inbred BN; Rats, Inbred Lew; Tenofovir; Teratogens; Thioguanine | 1997 |
9-(2-phosphonylmethoxyethyl) derivatives of purine nucleotide analogs: A comparison of their metabolism and interaction with cellular DNA synthesis.
Topics: Adenine; Antineoplastic Agents; Deoxyadenine Nucleotides; DNA; DNA Polymerase I; DNA Polymerase II; DNA Polymerase III; Guanine; Humans; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Tumor Cells, Cultured | 1999 |