Page last updated: 2024-08-24

adapalene and tretinoin

adapalene has been researched along with tretinoin in 80 studies

Research

Studies (80)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	22 (27.50)	18.2507
2000's	39 (48.75)	29.6817
2010's	13 (16.25)	24.3611
2020's	6 (7.50)	2.80

Authors

Authors	Studies
Bernardon, JM; Charpentier, B; Eustache, J; Martin, B; Michel, S; Millois, C; Shroot, B	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bhuiyan, M; Chao, WR; Dawson, MI; Farhana, L; Feng, GS; Fontana, JA; Han, YH; Hobbs, PD; Jiang, T; Jong, L; Macchiarulo, A; Nuti, R; Pang, Y; Patel, B; Pellicciari, R; Su, Y; Tautz, L; Waleh, N; Xia, Z; Xue, LP; Ye, M; Zhang, XK	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Abdeen, S; Chapman, E; Chitre, S; Hoang, QQ; Johnson, SM; Park, Y; Ray, AM; Salim, N; Sivinski, J; Stevens, M; Washburn, A	1
Czernielewski, J; Jablonska, S; Langner, A; Schaefer, H; Verschoore, M; Wolska, H	1
Bernerd, F; Bouclier, M; Chatelus, A; Hensby, C; Ortonne, JP	1
Bernard, BA; Cromie, MA; Elder, JT; Finkel, LJ; Griffiths, CE; Rossio, P; Shroot, B; Voorhees, JJ	1
Bouclier, M; Czernielewski, J; Hensby, C; Verschoore, M	1
Chen, S; Darling, IM; Mansuri, MM; Starrett, JE; Tramposch, KM; Whiting, G; Yu, KL	1
Baker, M; Chalker, DK; Czernielewski, J; Ellis, CN; Greenspan, A; Kantor, I; Katz, HI; Millikan, LE; Shalita, A; Swinehart, T; Swinyer, L; Weiss, JS; Whitmore, C	1
Alirezai, M; Czernielewski, J; Jablonska, S; Meynadier, J; Verschoore, M	1
Baker, M; Clucas, A; Czernielewski, J; Poncet, M; Sorba, V; Verschoore, M	1
Alirezai, M; Caputo, R; Chalker, DK; Cunliffe, WJ; Czernielewski, J; Dreno, B; Ellis, CN; Förström, L; Greenspan, A; Heenen, M; Jablonska, S; Kantor, I; Katz, HI; Meynadier, J; Millikan, LE; Orfanos, CE; Privat, Y; Robledo Aguilar, A; Shalita, A; Swinehart, JM; Swinyer, L; Verschoore, M; Weiss, JS; Whitmore, C	1
Leyden, JJ	2
Démarchez, M; Jomard, A; Michel, S	1
Martin, B; Meunier, C; Montels, D; Watts, O	1
Ancian, P; Clucas, A; Griffiths, CE; Humphries, J; Michel, S; Poncet, M; Rizova, E	1
Baker, MD; Dunlap, FE; Mills, OH; Plott, RT; Tuley, MR	1
Alirezai, M; Clucas, A; Finlay, AY; Grosshans, E; Marks, R; Mascaro, JM; Meynadier, J; Poncet, M; Soto, P; Torras, H; Verschoore, M	1
Baker, M; Galvin, SA; Gilbert, R; Guibal, F; Tuley, MR	1
Baker, M; Berger, RS; Chalker, DM; Ellis, CN; Katz, IH; Loesche, C; Millikan, LE; Mills, OH; Smith, EB; Swinyer, LJ; Verschoore, M	1
Cunliffe, WJ; Loesche, C; Poncet, M; Verschoore, M	1
Fraiture, AL; Fumal, I; Henry, F; Piérard, GE; Piérard-Franchimont, C	1
Cornell, DH	1
Bowman, JP; Lockhart, L; Novack, GD; Potrebka, J; Toole, JW	1
Ciletti, N; Kim, MJ; Michel, S; Reichert, U; Rosenfield, RL	1
Kakita, L	1
Baker, M; Clucas, A; Mesaros, S; Poncet, M; Queille-Roussel, C; Soloff, AM	1
Bershad, S	1
Millikan, LE	1
Wolf, JE	1
Li, GQ; Tu, P; Wong, WZ; Zheng, J; Zhu, XJ	1
Baker, M; Gold, MH; Jarratt, MT; Kang, S; Kaplan, DL; Loesche, C; Millikan, L; Thiboutot, D; Wolfe, J	1
Baker, MM; Egan, N; Loesche, MC	1
Duan, YQ; Tu, P; Zhen, J; Zhu, XJ	1
Dogra, S; Kanwar, AJ; Parsad, D	1
Berger, RS; Grossman, RM; Jorizzo, JL; Kim, YH; Martin, AG; Nighland, M; Nyirady, J; Pandya, AG; Schulz, KK; Strauss, JS	1
Liao, DC	1
Sardana, K; Sehgal, VN	1
Baker, MD; Georgeian, K; Gilbert, R; Greenspan, A; Loesche, C; Poncet, M; Soto, P; Vendetti, N	1
Ganslmayer, M; Hahn, EG; Herold, C; Ocker, M; Schuppan, D	1
Baker, MD; Brand, B; Georgeian, K; Gilbert, R; Greenspan, A; Poncet, M; Soto, P	1
Ganslmayer, M; Hahn, EG; Herold, C; Ocker, M; Schuppan, D; Zopf, S	1
Biyun, C	1
Del Rosso, JQ	1
Noble, S; Scott, LJ; Waugh, J	1
Jain, S	1
Arsonnaud, S; Dosik, JS; Homer, K	1
Akdeniz, N; Calka, O; Metin, A; Ozbek, H	1
Purdy, S	2
Scheinfeld, N	1
Kircik, L	1
Taylor, SC	1
Bikowski, J; Callender, VD; Del Rosso, JQ; Draelos, ZD; Tanghetti, E	1
Date, A; Korting, HC; Mukherjee, S; Patravale, V; Roeder, A; Weindl, G	1
Bikowski, J; Del Rosso, JQ	1
Grossman, R; Leyden, JJ; Nighland, M	1
Gollnick, H; Thielitz, A	1
Baldwin, EK; Leyden, J; Wortzman, M	1
Briantais, P; Goh, CL; Kaoukhov, A; Soto, P; Tang, MB	1
Leyden, JJ; Nighland, M; Ramaswamy, R; Rossi, AB	1
Cozzani, E; Drago, F; Gallo, R; Paolino, S; Parodi, A	1
Franz, TJ; Lehman, PA	1
Ehst, BD; Goreshi, R; Samrao, A	1
Bonifaz, A; Espíndola, YS; Ponce-Olivera, RM; Tirado-Sánchez, A	1
Elliott, L; Fisher, S; Kobraei, K; Lessner, E; Lessner, R; Osleber, M; Wesson, S	1
Jiang, P; Jin, X; Liao, W; Xing, F; Xu, W	1
Bonati, LM; Silverberg, NB; Yeh, L	1
Almeida, LMC; Bagatin, E; Gonçalves, HS; Miot, HA; Sato, M	1
Chen, J; Fang, Z; Gao, L; Li, B; Li, Y; Shen, F; Wang, L; Wang, Y; Wu, M; Ye, J; Yuan, Z	1
Chaithirayanon, S; Treesirichod, A; Wongjitrat, N	1
Abdelmaksoud, A; Galadari, H; Goldust, M; Grabbe, S; Gupta, M; Karagaiah, P; Kassir, M; Katsambas, A; Lotti, T; Sonthalia, S; Wollina, U	1
Liu, GJ; Liu, H; Liu, L; Peinemann, F; Sang, H; Xia, J; Yu, H	1
Maruthappu, T; Taylor, M	1
Chatim, A; Feldman, S; Kankaria, A; Singh, R	1
Milosheska, D; Roškar, R	1

Reviews

24 review(s) available for adapalene and tretinoin

Article	Year
Topical retinoids. Their uses in dermatology. Dermatologic clinics, 1993, Volume: 11, Issue:1 Topics: Adapalene; Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Humans; Isotretinoin; Mice; Models, Biological; Naphthalenes; Psoriasis; Retinoids; Skin Aging; Skin Diseases; Tretinoin	1993
Topical treatment of acne vulgaris: retinoids and cutaneous irritation. Journal of the American Academy of Dermatology, 1998, Volume: 38, Issue:4 Topics: Acne Vulgaris; Adapalene; Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Gels; Humans; Keratolytic Agents; Naphthalenes; Nicotinic Acids; Ointments; Retinoids; Tretinoin	1998
A comparison of the efficacy and tolerability of adapalene 0.1% gel versus tretinoin 0.025% gel in patients with acne vulgaris: a meta-analysis of five randomized trials. The British journal of dermatology, 1998, Volume: 139 Suppl 52 Topics: Acne Vulgaris; Adapalene; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug Eruptions; Gels; Humans; Keratolytic Agents; Multicenter Studies as Topic; Naphthalenes; Randomized Controlled Trials as Topic; Treatment Outcome; Tretinoin	1998
Tazarotene versus tretinoin or adapalene in the treatment of acne vulgaris. Journal of the American Academy of Dermatology, 2000, Volume: 43, Issue:2 Pt 3 Topics: Acne Vulgaris; Adapalene; Administration, Topical; Dermatologic Agents; Double-Blind Method; Gels; Keratolytic Agents; Multicenter Studies as Topic; Naphthalenes; Nicotinic Acids; Randomized Controlled Trials as Topic; Treatment Outcome; Tretinoin	2000
Developments in topical retinoid therapy for acne. Seminars in cutaneous medicine and surgery, 2001, Volume: 20, Issue:3 Topics: Acne Vulgaris; Adapalene; Dermatologic Agents; Drug Combinations; Humans; Keratolytic Agents; Naphthalenes; Nicotinic Acids; Receptors, Retinoic Acid; Tretinoin; Vitamin A	2001
Pivotal clinical trials of adapalene in the treatment of acne. Journal of the European Academy of Dermatology and Venereology : JEADV, 2001, Volume: 15 Suppl 3 Topics: Acne Vulgaris; Adapalene; Administration, Topical; Adolescent; Adult; Controlled Clinical Trials as Topic; Female; Follow-Up Studies; Humans; Male; Naphthalenes; Sensitivity and Specificity; Treatment Outcome; Tretinoin	2001
An update of recent clinical trials examining adapalene and acne. Journal of the European Academy of Dermatology and Venereology : JEADV, 2001, Volume: 15 Suppl 3 Topics: Acne Vulgaris; Adapalene; Administration, Topical; Adolescent; Adult; Controlled Clinical Trials as Topic; Female; Follow-Up Studies; Humans; Male; Naphthalenes; Probability; Treatment Outcome; Tretinoin	2001
Management of acne. The Journal of family practice, 2003, Volume: 52, Issue:1 Topics: Acne Vulgaris; Adapalene; Administration, Oral; Administration, Topical; Algorithms; Anti-Bacterial Agents; Benzoyl Peroxide; Contraceptives, Oral; Controlled Clinical Trials as Topic; Cost-Benefit Analysis; Decision Trees; Dermatologic Agents; Dicarboxylic Acids; Humans; Isotretinoin; Macrolides; Naphthalenes; Nicotinic Acids; Salicylates; Tretinoin; United States	2003
Retinoids: fascinating up-and-coming scenario. The Journal of dermatology, 2003, Volume: 30, Issue:5 Topics: Acne Vulgaris; Adapalene; Administration, Cutaneous; Administration, Oral; Chemistry, Pharmaceutical; Humans; Isotretinoin; Naphthalenes; Psoriasis; Receptors, Retinoic Acid; Retinoids; Skin Diseases; Tretinoin	2003
Topical retinoids in the management of acne: the best path to clear results. Cutis, 2004, Volume: 74, Issue:4 Suppl Topics: Acne Vulgaris; Adapalene; Dermatologic Agents; Humans; Keratolytic Agents; Meta-Analysis as Topic; Multicenter Studies as Topic; Naphthalenes; Nicotinic Acids; Randomized Controlled Trials as Topic; Retinoids; Treatment Outcome; Tretinoin; United States	2004
Meta-analysis of topical tazarotene in the treatment of mild to moderate acne. Cutis, 2004, Volume: 74, Issue:4 Suppl Topics: Acne Vulgaris; Adapalene; Administration, Cutaneous; Adult; Dermatologic Agents; Drug Administration Schedule; Female; Gels; Humans; Male; Multicenter Studies as Topic; Naphthalenes; Nicotinic Acids; Randomized Controlled Trials as Topic; Retinoids; Severity of Illness Index; Time Factors; Treatment Outcome; Tretinoin; United States	2004
Spotlight on adapalene in acne vulgaris. American journal of clinical dermatology, 2004, Volume: 5, Issue:5 Topics: Acne Vulgaris; Adapalene; Administration, Cutaneous; Anti-Inflammatory Agents, Non-Steroidal; Dermatologic Agents; Drug Administration Schedule; Gels; Humans; Multicenter Studies as Topic; Naphthalenes; Nicotinic Acids; Randomized Controlled Trials as Topic; Treatment Outcome; Tretinoin	2004
Topical tretinoin or adapalene in acne vulgaris: an overview. The Journal of dermatological treatment, 2004, Volume: 15, Issue:4 Topics: Acne Vulgaris; Adapalene; Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Humans; Keratolytic Agents; Naphthalenes; Tretinoin	2004
Acne vulgaris. Clinical evidence, 2005, Issue:13 Topics: Acne Vulgaris; Adapalene; Anti-Bacterial Agents; Benzoyl Peroxide; Clindamycin; Dermatologic Agents; Dicarboxylic Acids; Drug Therapy, Combination; Erythromycin; Humans; Isotretinoin; Naphthalenes; Tetracycline; Tretinoin; Zinc	2005
Acne vulgaris. Clinical evidence, 2006, Issue:15 Topics: Acne Vulgaris; Adapalene; Anti-Bacterial Agents; Benzoyl Peroxide; Clindamycin; Dermatologic Agents; Dicarboxylic Acids; Doxycycline; Erythromycin; Humans; Isotretinoin; Minocycline; Naphthalenes; Tetracycline; Tretinoin; Zinc	2006
Schools of pharmacology: retinoid update. Journal of drugs in dermatology : JDD, 2006, Volume: 5, Issue:9 Topics: Adapalene; Humans; Isotretinoin; Keratolytic Agents; Naphthalenes; Nicotinic Acids; Retinoids; Skin Diseases; Tretinoin	2006
Utilizing combination therapy for ethnic skin. Cutis, 2007, Volume: 80, Issue:1 Suppl Topics: Acne Vulgaris; Adapalene; Anti-Bacterial Agents; Asian People; Benzoyl Peroxide; Black or African American; Clindamycin; Dermatologic Agents; Dimethylpolysiloxanes; Drug Combinations; Drug Therapy, Combination; Glycerol; Hispanic or Latino; Humans; Hyperpigmentation; Keratolytic Agents; Naphthalenes; Randomized Controlled Trials as Topic; Skin Pigmentation; Tretinoin	2007
Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 2006, Volume: 1, Issue:4 Topics: Adapalene; Dermatologic Agents; Dermis; Epidermis; Humans; Naphthalenes; Nicotinic Acids; Retinaldehyde; Retinoids; Skin Aging; Treatment Outcome; Tretinoin; Vitamin A Deficiency	2006
Topical retinoids in acne vulgaris: update on efficacy and safety. American journal of clinical dermatology, 2008, Volume: 9, Issue:6 Topics: Acne Vulgaris; Adapalene; Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Drug Therapy, Combination; Humans; Isotretinoin; Naphthalenes; Nicotinic Acids; Retinoids; Safety; Tretinoin	2008
Selective RAR agonists for acne vulgaris: A narrative review. Journal of cosmetic dermatology, 2020, Volume: 19, Issue:6 Topics: Acne Vulgaris; Adapalene; Administration, Cutaneous; Dermatologic Agents; Humans; Nicotinic Acids; Randomized Controlled Trials as Topic; Receptors, Retinoic Acid; Retinoids; Treatment Outcome; Tretinoin	2020
Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne. The Cochrane database of systematic reviews, 2020, 05-01, Volume: 5 Topics: Acne Vulgaris; Adapalene; Adolescent; Adult; Anti-Bacterial Agents; Benzoyl Peroxide; Bias; Child; Clindamycin; Dermatologic Agents; Dicarboxylic Acids; Erythromycin; Female; Glycolates; Humans; Keratolytic Agents; Male; Mandelic Acids; Niacinamide; Patient Dropouts; Pyruvic Acid; Quality of Life; Salicylic Acid; Sulfur; Tretinoin; Young Adult; Zinc	2020
Acne and rosacea in skin of colour. Clinical and experimental dermatology, 2022, Volume: 47, Issue:2 Topics: Acne Vulgaris; Adapalene; Diagnosis, Differential; Dicarboxylic Acids; Humans; Racial Groups; Rosacea; Skin Pigmentation; Tretinoin	2022
Review of Tretinoin-Benzoyl Peroxide in The Treatment of Acne Vulgaris. Journal of drugs in dermatology : JDD, 2022, Oct-01, Volume: 21, Issue:10 Topics: Acne Vulgaris; Adapalene; Benzoyl Peroxide; Dermatologic Agents; Double-Blind Method; Drug Combinations; Gels; Humans; Immunoglobulin A; Treatment Outcome; Tretinoin	2022
Use of Retinoids in Topical Antiaging Treatments: A Focused Review of Clinical Evidence for Conventional and Nanoformulations. Advances in therapy, 2022, Volume: 39, Issue:12 Topics: Adapalene; Cosmeceuticals; Dermatologic Agents; Humans; Retinoids; Tretinoin	2022

Trials

33 trial(s) available for adapalene and tretinoin

Article	Year
Efficacy and safety of CD 271 alcoholic gels in the topical treatment of acne vulgaris. The British journal of dermatology, 1991, Volume: 124, Issue:4 Topics: Acne Vulgaris; Adapalene; Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Humans; Male; Naphthalenes; Tretinoin	1991
Comparison of CD271 (adapalene) and all-trans retinoic acid in human skin: dissociation of epidermal effects and CRABP-II mRNA expression. The Journal of investigative dermatology, 1993, Volume: 101, Issue:3 Topics: Adapalene; Administration, Topical; Blotting, Northern; Carrier Proteins; Erythema; Gene Expression; Humans; Immunohistochemistry; Naphthalenes; Receptors, Retinoic Acid; RNA, Messenger; Skin; Tretinoin	1993
A comparison of the efficacy and safety of adapalene gel 0.1% and tretinoin gel 0.025% in the treatment of acne vulgaris: a multicenter trial. Journal of the American Academy of Dermatology, 1996, Volume: 34, Issue:3 Topics: Acne Vulgaris; Adapalene; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Child; Drug Eruptions; Drug Tolerance; Erythema; Facial Dermatoses; Female; Gels; Humans; Keratolytic Agents; Male; Naphthalenes; Pruritus; Single-Blind Method; Skin Diseases; Tretinoin	1996
[Comparative study of the efficacy and tolerability of 0.1 and 0.03 p.100 adapalene gel and 0.025 p.100 tretinoin gel in the treatment of acne]. Annales de dermatologie et de venereologie, 1996, Volume: 123, Issue:3 Topics: Acne Vulgaris; Adapalene; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Gels; Humans; Keratolytic Agents; Male; Naphthalenes; Time Factors; Tretinoin	1996
Adapalene 0.1% gel is better tolerated than tretinoin 0.025% gel in acne patients. Journal of the American Academy of Dermatology, 1997, Volume: 36, Issue:6 Pt 2 Topics: Acne Vulgaris; Adapalene; Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Child; Female; Humans; Keratolytic Agents; Male; Naphthalenes; Skin; Treatment Outcome; Tretinoin	1997
Clinical efficacy and safety comparison of adapalene gel and tretinoin gel in the treatment of acne vulgaris: Europe and U.S. multicenter trials. Journal of the American Academy of Dermatology, 1997, Volume: 36, Issue:6 Pt 2 Topics: Adapalene; Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Child; Dose-Response Relationship, Drug; Europe; Female; Gels; Humans; Keratolytic Agents; Male; Naphthalenes; Treatment Outcome; Tretinoin; United States	1997
Adapalene 0.1% gel and adapalene 0.1% cream stimulate retinoic acid receptor mediated gene transcription without significant irritative effects in the skin of healthy human volunteers. The British journal of dermatology, 1998, Volume: 139 Suppl 52 Topics: Adapalene; Anti-Inflammatory Agents, Non-Steroidal; Erythema; Gels; Humans; Keratolytic Agents; Naphthalenes; Ointments; Receptors, Retinoic Acid; Transcription, Genetic; Tretinoin	1998
Adapalene 0.1% gel for the treatment of acne vulgaris: its superiority compared to tretinoin 0.025% cream in skin tolerance and patient preference. The British journal of dermatology, 1998, Volume: 139 Suppl 52 Topics: Acne Vulgaris; Adapalene; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug Eruptions; Female; Gels; Humans; Keratolytic Agents; Male; Naphthalenes; Ointments; Patient Satisfaction; Tretinoin	1998
Evaluation of clinical efficacy and safety of adapalene 0.1% gel versus tretinoin 0.025% gel in the treatment of acne vulgaris, with particular reference to the onset of action and impact on quality of life. The British journal of dermatology, 1998, Volume: 139 Suppl 52 Topics: Acne Vulgaris; Adapalene; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Child; Double-Blind Method; Drug Eruptions; Female; Humans; Keratolytic Agents; Male; Naphthalenes; Quality of Life; Treatment Outcome; Tretinoin	1998
Comparative tolerance of adapalene 0.1% gel and six different tretinoin formulations. The British journal of dermatology, 1998, Volume: 139 Suppl 52 Topics: Acne Vulgaris; Adapalene; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug Eruptions; Female; Gels; Humans; Keratolytic Agents; Male; Middle Aged; Naphthalenes; Ointments; Tretinoin	1998
Comparison of adapalene 0.1% solution and tretinoin 0.025% gel in the topical treatment of acne vulgaris. The British journal of dermatology, 1998, Volume: 139 Suppl 52 Topics: Acne Vulgaris; Adapalene; Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Child; Double-Blind Method; Drug Eruptions; Female; Gels; Humans; Keratolytic Agents; Male; Naphthalenes; Treatment Outcome; Tretinoin	1998
Split-face clinical and bio-instrumental comparison of 0.1% adapalene and 0.05% tretinoin in facial acne. Dermatology (Basel, Switzerland), 1999, Volume: 198, Issue:2 Topics: Acne Vulgaris; Adapalene; Administration, Topical; Adult; Dermatologic Agents; Facial Dermatoses; Humans; Keratolytic Agents; Male; Naphthalenes; Single-Blind Method; Skin; Tretinoin	1999
Comparative irritancy study among retinoid creams and gels. Journal of cutaneous medicine and surgery, 1999, Volume: 3, Issue:6 Topics: Adapalene; Adult; Dermatologic Agents; Gels; Humans; Irritants; Naphthalenes; Ointments; Retinoids; Skin; Tretinoin	1999
Comparison of the cumulative irritation potential of adapalene gel and cream with that of erythromycin/tretinoin solution and gel and erythromycin/isotretinoin gel. Clinical therapeutics, 2001, Volume: 23, Issue:2 Topics: Adapalene; Adolescent; Adult; Dermatologic Agents; Drug Combinations; Erythromycin; Female; Gels; Humans; Isotretinoin; Male; Middle Aged; Naphthalenes; Ointments; Single-Blind Method; Skin; Skin Irritancy Tests; Solutions; Tretinoin	2001
A comparison of adapalene gel 0.1% vs. tretinoin gel 0.025% in the treatment of acne vulgaris in China. Journal of the European Academy of Dermatology and Venereology : JEADV, 2001, Volume: 15 Suppl 3 Topics: Acne Vulgaris; Adapalene; Administration, Topical; Adolescent; Adult; China; Dermatologic Agents; Drug Administration Schedule; Female; Follow-Up Studies; Gels; Humans; Male; Naphthalenes; Severity of Illness Index; Treatment Outcome; Tretinoin	2001
Randomized controlled trial of the tolerability, safety, and efficacy of adapalene gel 0.1% and tretinoin microsphere gel 0.1% for the treatment of acne vulgaris. Cutis, 2001, Volume: 68, Issue:4 Suppl Topics: Acne Vulgaris; Adapalene; Administration, Topical; Adolescent; Adult; Child; Dermatologic Agents; Female; Humans; Keratolytic Agents; Male; Naphthalenes; Sensitivity and Specificity; Treatment Outcome; Tretinoin	2001
Randomized, controlled, bilateral (split-face) comparison trial of the tolerability and patient preference of adapalene gel 0.1% and tretinoin microsphere gel 0.1% for the treatment of acne vulgaris. Cutis, 2001, Volume: 68, Issue:4 Suppl Topics: Acne Vulgaris; Adapalene; Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Dermatologic Agents; Female; Humans; Keratolytic Agents; Male; Naphthalenes; Patient Satisfaction; Treatment Outcome; Tretinoin	2001
Adapalene gel 0.1%: effective and well tolerated in the topical treatment of acne vulgaris in Chinese patients. Cutis, 2001, Volume: 68, Issue:4 Suppl Topics: Acne Vulgaris; Adapalene; Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; China; Female; Humans; Keratolytic Agents; Male; Naphthalenes; Sensitivity and Specificity; Treatment Outcome; Tretinoin	2001
Adapalene in the treatment of melasma: a preliminary report. The Journal of dermatology, 2002, Volume: 29, Issue:8 Topics: Adapalene; Adult; Dermatologic Agents; Facial Dermatoses; Female; Humans; Keratolytic Agents; Melanosis; Naphthalenes; Tretinoin	2002
A comparative trial of two retinoids commonly used in the treatment of acne vulgaris. The Journal of dermatological treatment, 2001, Volume: 12, Issue:3 Topics: Acne Vulgaris; Adapalene; Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Child; Dermatologic Agents; Double-Blind Method; Female; Gels; Humans; Keratolytic Agents; Male; Naphthalenes; Treatment Outcome; Tretinoin	2001
Cumulative irritation comparison of adapalene gel and solution with 2 tazarotene gels and 3 tretinoin formulations. Cutis, 2003, Volume: 72, Issue:1 Topics: Adapalene; Adult; Aged; Dermatologic Agents; Double-Blind Method; Drug Interactions; Erythema; Female; Gels; Humans; Male; Middle Aged; Naphthalenes; Nicotinic Acids; Probability; Sensitivity and Specificity; Skin Irritancy Tests; Tretinoin	2003
Cumulative irritancy potential of adapalene cream 0.1% compared with adapalene gel 0.1% and several tretinoin formulations. Cutis, 2003, Volume: 72, Issue:6 Topics: Adapalene; Analysis of Variance; Dermatologic Agents; Female; Gels; Humans; Male; Middle Aged; Naphthalenes; Ointments; Skin Irritancy Tests; Tretinoin	2003
[The clinical observation of treating acne vulgaris with "xiao cuo fang"]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2004, Volume: 27, Issue:4 Topics: Acne Vulgaris; Adapalene; Administration, Topical; Adult; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Gels; Humans; Male; Naphthalenes; Phytotherapy; Tretinoin	2004
Cumulative irritation potential of adapalene 0.1% cream and gel compared with tretinoin microsphere 0.04% and 0.1%. Cutis, 2005, Volume: 75, Issue:4 Topics: Adapalene; Adult; Dermatologic Agents; Dose-Response Relationship, Drug; Double-Blind Method; Drug Eruptions; Erythema; Female; Gels; Humans; Male; Microspheres; Middle Aged; Naphthalenes; Ointments; Pruritus; Skin; Tretinoin	2005
Community-based trial results of combination clindamycin 1%--benzoyl peroxide 5% topical gel plus tretinoin microsphere gel 0.04% or 0.1% or adapalene gel 0.1% in the treatment of moderate to severe acne. Cutis, 2007, Volume: 80, Issue:1 Suppl Topics: Acne Vulgaris; Adapalene; Administration, Cutaneous; Administration, Topical; Adult; Anti-Bacterial Agents; Benzoyl Peroxide; Clindamycin; Dermatologic Agents; Drug Combinations; Drug Therapy, Combination; Female; Gels; Humans; Male; Microspheres; Naphthalenes; Propionibacterium acnes; Severity of Illness Index; Treatment Outcome; Tretinoin	2007
Tolerability of clindamycin/tretinoin gel vs. tretinoin microsphere gel and adapalene gel. Journal of drugs in dermatology : JDD, 2009, Volume: 8, Issue:4 Topics: Acne Vulgaris; Adapalene; Adolescent; Adult; Anti-Bacterial Agents; Clindamycin; Dermatologic Agents; Drug Combinations; Female; Gels; Humans; Male; Microspheres; Naphthalenes; Tretinoin; Young Adult	2009
Adapalene gel 0.1% is better tolerated than tretinoin gel 0.025% among healthy volunteers of various ethnic origins. The Journal of dermatological treatment, 2009, Volume: 20, Issue:5 Topics: Adapalene; Administration, Cutaneous; Adolescent; Adult; Aged; Dermatologic Agents; Gels; Humans; Middle Aged; Naphthalenes; Single-Blind Method; Skin Diseases; Skin Irritancy Tests; Tretinoin; Young Adult	2009
Irritation potential of tretinoin gel microsphere pump versus adapalene plus benzoyl peroxide gel. Journal of drugs in dermatology : JDD, 2010, Volume: 9, Issue:8 Topics: Acne Vulgaris; Adapalene; Administration, Cutaneous; Adolescent; Adult; Benzoyl Peroxide; Dermatologic Agents; Drug Combinations; Female; Gels; Humans; Keratolytic Agents; Male; Microspheres; Naphthalenes; Pilot Projects; Single-Blind Method; Treatment Outcome; Tretinoin; Young Adult	2010
Assessing the bioequivalence of topical retinoid products by pharmacodynamic assay. Skin pharmacology and physiology, 2012, Volume: 25, Issue:5 Topics: Adapalene; Administration, Cutaneous; Adolescent; Adult; Dermatologic Agents; Dose-Response Relationship, Drug; Female; Gels; Humans; Male; Middle Aged; Models, Biological; Naphthalenes; Pilot Projects; Sensitivity and Specificity; Skin Absorption; Therapeutic Equivalency; Tretinoin; Water Loss, Insensible; Young Adult	2012
A double-blind, randomized, bilateral comparison of skin irritancy following application of the combination acne products clindamycin/tretinoin and benzoyl peroxide/adapalene. Journal of drugs in dermatology : JDD, 2012, Volume: 11, Issue:12 Topics: Acne Vulgaris; Adapalene; Adult; Anti-Bacterial Agents; Benzoyl Peroxide; Clindamycin; Dermatologic Agents; Diagnostic Self Evaluation; Double-Blind Method; Drug Combinations; Erythema; Female; Humans; Irritants; Keratolytic Agents; Linear Models; Male; Naphthalenes; Pruritus; Skin; Tretinoin; Water Loss, Insensible; Young Adult	2012
Efficacy and safety of adapalene gel 0.1% and 0.3% and tretinoin gel 0.05% for acne vulgaris: results of a single-center, randomized, double-blinded, placebo-controlled clinical trial on Mexican patients (skin type III-IV). Journal of cosmetic dermatology, 2013, Volume: 12, Issue:2 Topics: Acne Vulgaris; Adapalene; Adolescent; Adult; Child; Dermatitis, Irritant; Dermatologic Agents; Double-Blind Method; Female; Gels; Humans; Hyperpigmentation; Keratolytic Agents; Male; Mexico; Naphthalenes; Pruritus; Tretinoin; Young Adult	2013
Comparable efficacy of adapalene 0.3% gel and tretinoin 0.05% cream as treatment for cutaneous photoaging. European journal of dermatology : EJD, 2018, Jun-01, Volume: 28, Issue:3 Topics: Adapalene; Adult; Dermatologic Agents; Equivalence Trials as Topic; Female; Gels; Humans; Male; Middle Aged; Single-Blind Method; Skin Aging; Skin Cream; Sunlight; Tretinoin; Ultraviolet Rays	2018
Comparison of the efficacy and safety of 0.1% adapalene gel and 0.025% tretinoin cream in the treatment of childhood acanthosis nigricans. Pediatric dermatology, 2019, Volume: 36, Issue:3 Topics: Acanthosis Nigricans; Adapalene; Administration, Cutaneous; Adolescent; Child; Dermatologic Agents; Double-Blind Method; Female; Gels; Humans; Keratolytic Agents; Male; Neck; Skin Cream; Treatment Outcome; Tretinoin	2019

Other Studies

23 other study(ies) available for adapalene and tretinoin

Article	Year
Synthesis, structure-affinity relationships, and biological activities of ligands binding to retinoic acid receptor subtypes. Journal of medicinal chemistry, 1995, Dec-22, Volume: 38, Issue:26 Topics: Animals; Cell Differentiation; Magnetic Resonance Spectroscopy; Mice; Receptors, Retinoic Acid; Recombinant Proteins; Retinoic Acid Receptor alpha; Retinoic Acid Receptor gamma; Retinoids; Structure-Activity Relationship; Teratocarcinoma; Tretinoin; Tumor Cells, Cultured	1995
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Adamantyl-substituted retinoid-derived molecules that interact with the orphan nuclear receptor small heterodimer partner: effects of replacing the 1-adamantyl or hydroxyl group on inhibition of cancer cell growth, induction of cancer cell apoptosis, and Journal of medicinal chemistry, 2008, Sep-25, Volume: 51, Issue:18 Topics: Adamantane; Antineoplastic Agents; Apoptosis; Cell Division; Cell Line, Tumor; Cinnamates; Dimerization; Enzyme Inhibitors; Humans; Models, Molecular; Neoplasms; Protein Tyrosine Phosphatase, Non-Receptor Type 11	2008
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
HSP60/10 chaperonin systems are inhibited by a variety of approved drugs, natural products, and known bioactive molecules. Bioorganic & medicinal chemistry letters, 2019, 05-01, Volume: 29, Issue:9 Topics: Biological Products; Chaperonin 10; Chaperonin 60; Escherichia coli; Humans; Inhibitory Concentration 50; Protein Folding; Rafoxanide; Salicylanilides; Suramin	2019
The rhino mouse model: the effects of topically applied all-trans retinoic acid and CD271 on the fine structure of the epidermis and utricle wall of pseudocomedones. Archives of dermatological research, 1991, Volume: 283, Issue:2 Topics: Adapalene; Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Epidermis; Female; Male; Mice; Mice, Hairless; Microscopy, Electron; Naphthalenes; Tretinoin	1991
In-vivo activity of retinoid esters in skin is related to in-vitro hydrolysis rate. The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:8 Topics: Adapalene; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Benzoates; Humans; Hydrolysis; Mice; Mice, Hairless; Naphthalenes; Retinoids; Saccule and Utricle; Skin; Structure-Activity Relationship; Tetrahydronaphthalenes; Tretinoin	1995
Pharmacology of adapalene. The British journal of dermatology, 1998, Volume: 139 Suppl 52 Topics: Acne Vulgaris; Adapalene; Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Cell Differentiation; Cell Division; Dermatologic Agents; Drug Interactions; HeLa Cells; Humans; Keratinocytes; Naphthalenes; Receptors, Cytoplasmic and Nuclear; Skin; Tretinoin	1998
Chemical stability of adapalene and tretinoin when combined with benzoyl peroxide in presence and in absence of visible light and ultraviolet radiation. The British journal of dermatology, 1998, Volume: 139 Suppl 52 Topics: Adapalene; Anti-Inflammatory Agents, Non-Steroidal; Benzoyl Peroxide; Chromatography, High Pressure Liquid; Drug Combinations; Drug Stability; Gels; Keratolytic Agents; Light; Naphthalenes; Tretinoin; Ultraviolet Rays	1998
A is for acne. New Jersey medicine : the journal of the Medical Society of New Jersey, 1999, Volume: 96, Issue:6 Topics: Acne Vulgaris; Adapalene; Administration, Topical; Adolescent; Adult; Anti-Bacterial Agents; Benzoyl Peroxide; Dermatologic Agents; Female; Humans; Isotretinoin; Male; Middle Aged; Naphthalenes; Recurrence; Tretinoin	1999
The role of specific retinoid receptors in sebocyte growth and differentiation in culture. The Journal of investigative dermatology, 2000, Volume: 114, Issue:2 Topics: Adapalene; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Differentiation; Cell Division; Cells, Cultured; Naphthalenes; Rats; Receptors, Retinoic Acid; Retinoid X Receptors; Sebum; Transcription Factors; Tretinoin	2000
The synthetic retinoid adapalene inhibits proliferation and induces apoptosis in colorectal cancer cells in vitro. International journal of cancer, 2003, Nov-10, Volume: 107, Issue:3 Topics: Adapalene; Alitretinoin; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspases; Cell Division; Colorectal Neoplasms; Humans; Naphthalenes; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tretinoin; Tumor Cells, Cultured	2003
Potentiated anticancer effects on hepatoma cells by the retinoid adapalene. Cancer letters, 2004, May-10, Volume: 208, Issue:1 Topics: Adapalene; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Carcinoma, Hepatocellular; Caspase 3; Caspases; Cell Cycle; Flow Cytometry; Humans; Immunoenzyme Techniques; Liver Neoplasms; Membrane Potentials; Mitochondria; Naphthalenes; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tretinoin; Tumor Cells, Cultured	2004
Anti-inflammatory effects of tretinoin (all-trans-retinoic acid) 0.1% and adapalene 0.1% in rats. Clinical and experimental dermatology, 2005, Volume: 30, Issue:5 Topics: Adapalene; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Dermatitis; Edema; Female; Male; Naphthalenes; Rats; Rats, Sprague-Dawley; Tretinoin	2005
Combining clindamycin 1%-benzoyl peroxide 5% gel with multiple therapeutic options. Cutis, 2006, Volume: 78, Issue:2 Suppl 1 Topics: Acne Vulgaris; Adapalene; Administration, Cutaneous; Administration, Oral; Adolescent; Adult; Anti-Bacterial Agents; Benzoyl Peroxide; Clindamycin; Dermatologic Agents; Drug Combinations; Female; Gels; Humans; Keratolytic Agents; Male; Minocycline; Naphthalenes; Nicotinic Acids; Retinoids; Treatment Outcome; Tretinoin	2006
Benzoyl peroxide microsphere cream as monotherapy and combination treatment of acne. Journal of drugs in dermatology : JDD, 2008, Volume: 7, Issue:6 Topics: Acne Vulgaris; Adapalene; Administration, Topical; Adolescent; Adult; Anti-Bacterial Agents; Benzoyl Peroxide; Dermatologic Agents; Drug Therapy, Combination; Female; Humans; Keratolytic Agents; Male; Microspheres; Minocycline; Naphthalenes; Tretinoin	2008
Cumulative irritation potential of topical retinoid formulations. Journal of drugs in dermatology : JDD, 2008, Volume: 7, Issue:8 Suppl Topics: Acne Vulgaris; Adapalene; Administration, Topical; Adult; Dermatologic Agents; Female; Humans; Irritants; Naphthalenes; Randomized Controlled Trials as Topic; Skin; Tretinoin	2008
[Treatment of rosacea]. Annales de dermatologie et de venereologie, 2011, Volume: 138 Suppl 2 Topics: Adapalene; Anti-Infective Agents; Cyclosporine; Dermatologic Agents; Dicarboxylic Acids; Humans; Immunosuppressive Agents; Isotretinoin; Keratolytic Agents; Metronidazole; Mite Infestations; Naphthalenes; Rosacea; Sulfacetamide; Tacrolimus; Tetracycline; Toluidines; Tretinoin	2011
Spironolactone and topical retinoids in adult female cyclical acne. Journal of drugs in dermatology : JDD, 2014, Volume: 13, Issue:2 Topics: Acne Vulgaris; Adapalene; Administration, Cutaneous; Adult; Dermatologic Agents; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Middle Aged; Naphthalenes; Retrospective Studies; Severity of Illness Index; Spironolactone; Treatment Outcome; Tretinoin; Young Adult	2014
Effect of retinoic acid on aquaporin 3 expression in keratinocytes. Genetics and molecular research : GMR, 2016, Mar-11, Volume: 15, Issue:1 Topics: Acitretin; Adapalene; Aquaporin 3; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Gene Expression Regulation; Humans; Isotretinoin; Keratinocytes; Tretinoin	2016
Topical retinoids for acne. Seminars in cutaneous medicine and surgery, 2016, Volume: 35, Issue:2 Topics: Acne Vulgaris; Adapalene; Administration, Cutaneous; Dermatologic Agents; Humans; Nicotinic Acids; Retinoids; Treatment Outcome; Tretinoin	2016
Identification of Retinoic Acid Receptor Agonists as Potent Hepatitis B Virus Inhibitors via a Drug Repurposing Screen. Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:12 Topics: Acitretin; Adapalene; Antiviral Agents; Cell Line; Cell Survival; Dermatologic Agents; Drug Repositioning; Drug Synergism; Gene Expression; Guanine; Hep G2 Cells; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatocytes; High-Throughput Screening Assays; Host-Pathogen Interactions; Humans; Keratolytic Agents; Nicotinic Acids; Receptors, Retinoic Acid; Transcription, Genetic; Tretinoin; Virus Replication	2018
Tretinoin/benzoyl peroxide cream (Twyneo) for acne. The Medical letter on drugs and therapeutics, 2022, 05-16, Volume: 64, Issue:1650 Topics: Acne Vulgaris; Adapalene; Administration, Cutaneous; Anti-Bacterial Agents; Benzoyl Peroxide; Clindamycin; Dermatologic Agents; Drug Combinations; Gels; Humans; Tretinoin	2022