Page last updated: 2024-08-24

adapalene and clindamycin

adapalene has been researched along with clindamycin in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.13)18.2507
2000's13 (40.63)29.6817
2010's14 (43.75)24.3611
2020's4 (12.50)2.80

Authors

AuthorsStudies
Caron, D; Clucas, A; Sorba, V; Verschoore, M1
Baker, MD; Czernielewski, J; Kaplan, D; Kraus, SJ; Liu, YS; Loven, KH; Rist, T; Swinyer, LJ; Wolf, JE1
Li, LF; Tu, YT; Zhang, JZ; Zheng, J1
Purdy, S2
Emtestam, L; Hagströmer, L; Nord, CE; Oprica, C1
Del Rosso, JQ1
Kircik, L1
Taylor, SC1
Bikowski, J; Callender, VD; Del Rosso, JQ; Draelos, ZD; Tanghetti, E1
Ambroziak, M; Chu, A; Goulden, V; Langner, A1
Baldwin, EK; Leyden, J; Wortzman, M1
Kim, MB; Ko, HC; Kwon, KS; Oh, CK; Seo, SH; Song, M1
Alió, AB; Barnard, J; Fischer, TC; Wohlrab, J; Zouboulis, CC1
Katsuura, J; Kubota, Y; Matsunaka, H; Moriue, T; Munehiro, A; Murakami, Y; Nakai, K; Shirahige, Y; Yoneda, K1
Kubota, Y; Matsunaka, H; Moriue, T; Munehiro, A; Murakami, Y; Nakai, K; Shirahige, Y; Yoneda, K1
Borelli, C; Burgdorf, W; Mehra, T; Röcken, M; Schaller, M1
Guerra-Tapia, A1
Ting, W1
Cirigliano, M; Gonzalez, P; Vila, R1
Ehst, BD; Goreshi, R; Samrao, A1
Grove, G; Gwazdauskas, J; Zerweck, C1
Bettoli, V; Montis, A; Ruina, G; Virgili, A; Zauli, S1
Bhatia, N; Bhatt, V; Martin, G; Pillai, R1
Czilli, T; Knezevic, S; Peters, C; Tan, J1
Kawada, A; Kurokawa, I; Oiso, N1
Ashique Rahman, MA; Hota, D; Maiti, R; Parida, S; Sirka, CS; Srinivasan, A1
Endo, A; Hatanaka, T; Hayashi, N; Kawashima, M; Kurokawa, I; Siakpere, O; Yamada, M1
Liu, GJ; Liu, H; Liu, L; Peinemann, F; Sang, H; Xia, J; Yu, H1
Baldwin, H; Beer, K; Bhatt, V; Callender, V; Draelos, Z; Gold, M; Kircik, LH; Lain, E; Pariser, DM; Pillai, R; Sadick, N; Stein Gold, L; Tanghetti, EA; Weiss, JS1
Ebell, MH1

Reviews

5 review(s) available for adapalene and clindamycin

ArticleYear
Acne vulgaris.
    Clinical evidence, 2005, Issue:13

    Topics: Acne Vulgaris; Adapalene; Anti-Bacterial Agents; Benzoyl Peroxide; Clindamycin; Dermatologic Agents; Dicarboxylic Acids; Drug Therapy, Combination; Erythromycin; Humans; Isotretinoin; Naphthalenes; Tetracycline; Tretinoin; Zinc

2005
Acne vulgaris.
    Clinical evidence, 2006, Issue:15

    Topics: Acne Vulgaris; Adapalene; Anti-Bacterial Agents; Benzoyl Peroxide; Clindamycin; Dermatologic Agents; Dicarboxylic Acids; Doxycycline; Erythromycin; Humans; Isotretinoin; Minocycline; Naphthalenes; Tetracycline; Tretinoin; Zinc

2006
Utilizing combination therapy for ethnic skin.
    Cutis, 2007, Volume: 80, Issue:1 Suppl

    Topics: Acne Vulgaris; Adapalene; Anti-Bacterial Agents; Asian People; Benzoyl Peroxide; Black or African American; Clindamycin; Dermatologic Agents; Dimethylpolysiloxanes; Drug Combinations; Drug Therapy, Combination; Glycerol; Hispanic or Latino; Humans; Hyperpigmentation; Keratolytic Agents; Naphthalenes; Randomized Controlled Trials as Topic; Skin Pigmentation; Tretinoin

2007
Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne.
    The Cochrane database of systematic reviews, 2020, 05-01, Volume: 5

    Topics: Acne Vulgaris; Adapalene; Adolescent; Adult; Anti-Bacterial Agents; Benzoyl Peroxide; Bias; Child; Clindamycin; Dermatologic Agents; Dicarboxylic Acids; Erythromycin; Female; Glycolates; Humans; Keratolytic Agents; Male; Mandelic Acids; Niacinamide; Patient Dropouts; Pyruvic Acid; Quality of Life; Salicylic Acid; Sulfur; Tretinoin; Young Adult; Zinc

2020
For Mild to Moderate Acne, Adapalene Plus Benzoyl Peroxide, Clindamycin Plus Benzoyl Peroxide, and Adapalene Alone Are Most Effective.
    American family physician, 2022, 06-01, Volume: 105, Issue:6

    Topics: Acne Vulgaris; Adapalene; Administration, Cutaneous; Benzoyl Peroxide; Clindamycin; Dermatologic Agents; Drug Combinations; Humans; Randomized Controlled Trials as Topic; Treatment Outcome

2022

Trials

20 trial(s) available for adapalene and clindamycin

ArticleYear
Skin tolerance of adapalene 0.1% gel in combination with other topical antiacne treatments.
    Journal of the American Academy of Dermatology, 1997, Volume: 36, Issue:6 Pt 2

    Topics: Adapalene; Administration, Topical; Adult; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Benzoyl Peroxide; Clindamycin; Double-Blind Method; Erythromycin; Female; Gels; Humans; Keratolytic Agents; Male; Middle Aged; Naphthalenes; Skin

1997
Efficacy and tolerability of combined topical treatment of acne vulgaris with adapalene and clindamycin: a multicenter, randomized, investigator-blinded study.
    Journal of the American Academy of Dermatology, 2003, Volume: 49, Issue:3 Suppl

    Topics: Acne Vulgaris; Adapalene; Administration, Topical; Adolescent; Adult; Child; Clindamycin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Naphthalenes; Probability; Reference Values; Severity of Illness Index; Single-Blind Method; Treatment Outcome

2003
A successful maintenance approach in inflammatory acne with adapalene gel 0.1% after an initial treatment in combination with clindamycin topical solution 1% or after monotherapy with clindamycin topical solution 1%.
    The Journal of dermatological treatment, 2004, Volume: 15, Issue:6

    Topics: Acne Vulgaris; Adapalene; Administration, Topical; Adolescent; Adult; Anti-Bacterial Agents; Child; Clindamycin; Dermatologic Agents; Drug Therapy, Combination; Female; Gels; Humans; Male; Naphthalenes; Single-Blind Method; Solutions

2004
Clinical and microbiological comparisons of isotretinoin vs. tetracycline in acne vulgaris.
    Acta dermato-venereologica, 2007, Volume: 87, Issue:3

    Topics: Acne Vulgaris; Adapalene; Administration, Oral; Administration, Topical; Adolescent; Adult; Anti-Bacterial Agents; Clindamycin; Dermatologic Agents; Drug Resistance, Bacterial; Drug Therapy, Combination; Female; Humans; Isotretinoin; Male; Naphthalenes; Quality of Life; Remission Induction; Sex Factors; Tetracycline; Treatment Outcome

2007
Study results of benzoyl peroxide 5%/clindamycin 1% topical gel, adapalene 0.1% gel, and use in combination for acne vulgaris.
    Journal of drugs in dermatology : JDD, 2007, Volume: 6, Issue:6

    Topics: Acne Vulgaris; Adapalene; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Benzoyl Peroxide; Clindamycin; Dermatologic Agents; Dose-Response Relationship, Drug; Drug Therapy, Combination; Erythema; Female; Gels; Humans; Male; Naphthalenes; Pruritus; Skin; Time Factors; Treatment Outcome

2007
Community-based trial results of combination clindamycin 1%--benzoyl peroxide 5% topical gel plus tretinoin microsphere gel 0.04% or 0.1% or adapalene gel 0.1% in the treatment of moderate to severe acne.
    Cutis, 2007, Volume: 80, Issue:1 Suppl

    Topics: Acne Vulgaris; Adapalene; Administration, Cutaneous; Administration, Topical; Adult; Anti-Bacterial Agents; Benzoyl Peroxide; Clindamycin; Dermatologic Agents; Drug Combinations; Drug Therapy, Combination; Female; Gels; Humans; Male; Microspheres; Naphthalenes; Propionibacterium acnes; Severity of Illness Index; Treatment Outcome; Tretinoin

2007
A randomized, single-blind comparison of topical clindamycin + benzoyl peroxide and adapalene in the treatment of mild to moderate facial acne vulgaris.
    The British journal of dermatology, 2008, Volume: 158, Issue:1

    Topics: Acne Vulgaris; Adapalene; Administration, Cutaneous; Adolescent; Adult; Anti-Bacterial Agents; Benzoyl Peroxide; Clindamycin; Dermatologic Agents; Drug Combinations; Female; Gram-Positive Bacterial Infections; Humans; Male; Naphthalenes; Propionibacterium; Severity of Illness Index; Single-Blind Method; Treatment Outcome

2008
Tolerability of clindamycin/tretinoin gel vs. tretinoin microsphere gel and adapalene gel.
    Journal of drugs in dermatology : JDD, 2009, Volume: 8, Issue:4

    Topics: Acne Vulgaris; Adapalene; Adolescent; Adult; Anti-Bacterial Agents; Clindamycin; Dermatologic Agents; Drug Combinations; Female; Gels; Humans; Male; Microspheres; Naphthalenes; Tretinoin; Young Adult

2009
Prospective, open-label, comparative study of clindamycin 1%/benzoyl peroxide 5% gel with adapalene 0.1% gel in Asian acne patients: efficacy and tolerability.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2009, Volume: 23, Issue:3

    Topics: Acne Vulgaris; Adapalene; Adult; Benzoyl Peroxide; Clindamycin; Drug Combinations; Female; Gels; Humans; Male; Naphthalenes; Prospective Studies

2009
Study of the efficacy, tolerability, and safety of 2 fixed-dose combination gels in the management of acne vulgaris.
    Cutis, 2009, Volume: 84, Issue:4

    Topics: Acne Vulgaris; Adapalene; Adolescent; Adult; Anti-Bacterial Agents; Benzoyl Peroxide; Child; Clindamycin; Dermatologic Agents; Drug Combinations; Excipients; Female; Gels; Humans; Male; Middle Aged; Naphthalenes; Prospective Studies; Single-Blind Method; Treatment Outcome; Young Adult

2009
Effect of sequential application of topical adapalene and clindamycin phosphate in the treatment of Japanese patients with acne vulgaris.
    The Journal of dermatological treatment, 2012, Volume: 23, Issue:1

    Topics: Acne Vulgaris; Adapalene; Adolescent; Adult; Anti-Bacterial Agents; Clindamycin; Dermatologic Agents; Drug Therapy, Combination; Female; Humans; Japan; Male; Middle Aged; Naphthalenes; Severity of Illness Index; Young Adult

2012
Effects of benzoyl peroxide 5% clindamycin combination gel versus adapalene 0.1% on quality of life in patients with mild to moderate acne vulgaris: a randomized single-blind study.
    Journal of drugs in dermatology : JDD, 2012, Volume: 11, Issue:6

    Topics: Acne Vulgaris; Adapalene; Adolescent; Adult; Benzoyl Peroxide; Child; Clindamycin; Drug Therapy, Combination; Female; Gels; Humans; Male; Naphthalenes; Quality of Life; Severity of Illness Index; Single-Blind Method; Surveys and Questionnaires; Treatment Outcome; Young Adult

2012
Randomized, observer-blind, split-face study to compare the irritation potential of 2 topical acne formulations over a 14-day treatment period.
    Cutis, 2012, Volume: 90, Issue:2

    Topics: Acne Vulgaris; Adapalene; Administration, Cutaneous; Adolescent; Adult; Anti-Bacterial Agents; Benzoyl Peroxide; Clindamycin; Dermatologic Agents; Drug Combinations; Erythema; Facial Dermatoses; Female; Gels; Humans; Intention to Treat Analysis; Male; Naphthalenes; Patient Preference; Single-Blind Method; Water Loss, Insensible; Young Adult

2012
The tolerability profile of clindamycin 1%/benzoyl peroxide 5% gel vs. adapalene 0.1%/benzoyl peroxide 2.5% gel for facial acne: results of a randomized, single-blind, split-face study.
    Journal of cosmetic dermatology, 2012, Volume: 11, Issue:4

    Topics: Acne Vulgaris; Adapalene; Adult; Anti-Bacterial Agents; Benzoyl Peroxide; Clindamycin; Dermatologic Agents; Drug Combinations; Erythema; Facial Dermatoses; Female; Gels; Humans; Male; Middle Aged; Naphthalenes; Pain; Patient Preference; Pruritus; Severity of Illness Index; Single-Blind Method; Statistics, Nonparametric; Young Adult

2012
A double-blind, randomized, bilateral comparison of skin irritancy following application of the combination acne products clindamycin/tretinoin and benzoyl peroxide/adapalene.
    Journal of drugs in dermatology : JDD, 2012, Volume: 11, Issue:12

    Topics: Acne Vulgaris; Adapalene; Adult; Anti-Bacterial Agents; Benzoyl Peroxide; Clindamycin; Dermatologic Agents; Diagnostic Self Evaluation; Double-Blind Method; Drug Combinations; Erythema; Female; Humans; Irritants; Keratolytic Agents; Linear Models; Male; Naphthalenes; Pruritus; Skin; Tretinoin; Water Loss, Insensible; Young Adult

2012
Tolerability and irritation potential of four topical acne regimens in healthy subjects.
    Journal of drugs in dermatology : JDD, 2013, Jun-01, Volume: 12, Issue:6

    Topics: Acne Vulgaris; Adapalene; Administration, Cutaneous; Benzoyl Peroxide; Clindamycin; Dapsone; Dermatologic Agents; Drug Combinations; Female; Follow-Up Studies; Gels; Humans; Male; Naphthalenes; Single-Blind Method

2013
Two Randomized, Double-Blind, Split-Face Studies to Compare the Irritation Potential of Two Topical Acne Fixed Combinations Over a 21-Day Treatment Period.
    Journal of drugs in dermatology : JDD, 2016, Jun-01, Volume: 15, Issue:6

    Topics: Acne Vulgaris; Adapalene; Administration, Cutaneous; Adult; Anti-Bacterial Agents; Clindamycin; Dermatitis, Irritant; Dermatologic Agents; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Humans; Male; Middle Aged; Treatment Outcome

2016
Efficacy and Safety of Tazarotene 0.1% Plus Clindamycin 1% Gel Versus Adapalene 0.1% Plus Clindamycin 1% Gel in Facial Acne Vulgaris: A Randomized, Controlled Clinical Trial.
    Clinical drug investigation, 2017, Volume: 37, Issue:11

    Topics: Acne Vulgaris; Adapalene; Adolescent; Adult; Anti-Bacterial Agents; Clindamycin; Dermatologic Agents; Drug Therapy, Combination; Female; Gels; Humans; Male; Nicotinic Acids; Quality of Life; Surveys and Questionnaires; Treatment Outcome; Young Adult

2017
Clindamycin phosphate 1.2%/benzoyl peroxide 3% fixed-dose combination gel versus topical combination therapy of adapalene 0.1% gel and clindamycin phosphate 1.2% gel in the treatment of acne vulgaris in Japanese patients: A multicenter, randomized, invest
    The Journal of dermatology, 2018, Volume: 45, Issue:8

    Topics: Acne Vulgaris; Adapalene; Administration, Cutaneous; Adolescent; Adult; Benzoyl Peroxide; Clindamycin; Combined Modality Therapy; Dermatologic Agents; Drug Combinations; Female; Gels; Humans; Japan; Male; Patient Preference; Quality of Life; Severity of Illness Index; Young Adult

2018
Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug.
    American journal of clinical dermatology, 2022, Volume: 23, Issue:1

    Topics: Acne Vulgaris; Adapalene; Administration, Topical; Adolescent; Adult; Benzoyl Peroxide; Child; Clindamycin; Dermatologic Agents; Double-Blind Method; Drug Combinations; Female; Humans; Male; Middle Aged; Young Adult

2022

Other Studies

7 other study(ies) available for adapalene and clindamycin

ArticleYear
Combining clindamycin 1%-benzoyl peroxide 5% gel with multiple therapeutic options.
    Cutis, 2006, Volume: 78, Issue:2 Suppl 1

    Topics: Acne Vulgaris; Adapalene; Administration, Cutaneous; Administration, Oral; Adolescent; Adult; Anti-Bacterial Agents; Benzoyl Peroxide; Clindamycin; Dermatologic Agents; Drug Combinations; Female; Gels; Humans; Keratolytic Agents; Male; Minocycline; Naphthalenes; Nicotinic Acids; Retinoids; Treatment Outcome; Tretinoin

2006
Combination effects of cosmetic moisturisers in the topical treatment of acne vulgaris.
    The Journal of dermatological treatment, 2012, Volume: 23, Issue:3

    Topics: Acne Vulgaris; Adapalene; Administration, Topical; Adult; Anti-Bacterial Agents; Asian People; Clindamycin; Cosmetics; Dermatologic Agents; Drug Therapy, Combination; Face; Gels; Humans; Male; Naphthalenes; Severity of Illness Index; Skin; Treatment Outcome

2012
Treatment of severe acne with low-dose isotretinoin.
    Acta dermato-venereologica, 2012, Volume: 92, Issue:3

    Topics: Acne Vulgaris; Adapalene; Adolescent; Adrenal Cortex Hormones; Anti-Bacterial Agents; Benzoyl Peroxide; Clindamycin; Dermatologic Agents; Drug Therapy, Combination; Erythromycin; Female; Humans; Isotretinoin; Male; Naphthalenes; Photography; Retrospective Studies; Severity of Illness Index

2012
Acneiform eruption due to vitamin B12: a problem still unsolved.
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2014, Volume: 149, Issue:1

    Topics: Acneiform Eruptions; Adapalene; Adult; Benzoyl Peroxide; Brain Damage, Chronic; Brain Injuries; Clindamycin; Drug Therapy, Combination; Facial Dermatoses; Female; Humans; Lymecycline; Male; Naphthalenes; Vitamin B 12

2014
Cost of Medications Recommended by Canadian Acne Clinical Practice Guidelines.
    Journal of cutaneous medicine and surgery, 2016, Volume: 20, Issue:6

    Topics: Acne Vulgaris; Adapalene; Administration, Cutaneous; Administration, Oral; Androgen Antagonists; Androstenes; Anti-Bacterial Agents; Benzoyl Peroxide; Canada; Clindamycin; Cyproterone Acetate; Dermatologic Agents; Doxycycline; Drug Combinations; Estrogens; Ethinyl Estradiol; Humans; Isotretinoin; Mineralocorticoid Receptor Antagonists; Minocycline; Practice Guidelines as Topic; Severity of Illness Index; Tetracycline

2016
Adjuvant alternative treatment with chemical peeling and subsequent iontophoresis for postinflammatory hyperpigmentation, erosion with inflamed red papules and non-inflamed atrophic scars in acne vulgaris.
    The Journal of dermatology, 2017, Volume: 44, Issue:4

    Topics: Acne Vulgaris; Adapalene; Adolescent; Adult; alpha-Tocopherol; Anti-Infective Agents; Ascorbic Acid; Atrophy; Benzoyl Peroxide; Chemexfoliation; Cicatrix; Clindamycin; Combined Modality Therapy; Erythema; Female; Glycolates; Humans; Hyperpigmentation; Iontophoresis; Japan; Male; Severity of Illness Index; Treatment Outcome; Young Adult

2017
Tretinoin/benzoyl peroxide cream (Twyneo) for acne.
    The Medical letter on drugs and therapeutics, 2022, 05-16, Volume: 64, Issue:1650

    Topics: Acne Vulgaris; Adapalene; Administration, Cutaneous; Anti-Bacterial Agents; Benzoyl Peroxide; Clindamycin; Dermatologic Agents; Drug Combinations; Gels; Humans; Tretinoin

2022