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adamantylamide-alanyl-isoglutamine and amantadine

adamantylamide-alanyl-isoglutamine has been researched along with amantadine in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19906 (23.08)18.7374
1990's10 (38.46)18.2507
2000's10 (38.46)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Masek, K; Masihi, KN; Palache, B; Rohde-Schulz, B1
Masek, K1
Buchar, E; Flegel, M; Janků, I; Machková, Z; Masek, K; Vrba, T; Walder, P1
Buchar, E; Farghali, H; Janků, I; Masek, K1
Gast, G; Huchshorn, P; Lange, W; Masek, K; Masihi, KN; Palache, A; Schwenke, S1
Gulda, O; Sulcová, A2
Celedová, L; Janku, I; Krsiak, M1
Gulda, O; Krsiak, M; Masek, K; Sulcová, A1
Horák, P; Masek, K1
Flegel, M; Kolínsky, J; Krojidlo, M; Masek, K; Seifert, J1
Zídek, Z1
Horavová, P; Krchnák, V; Novák, J; Toman, M; Turánek, J1
Flegel, M; Franková, D; Masek, K; Zídek, Z1
Botros, S; Hassan, S; Ibrahim, A; Mahmoud, S; Masek, K; Zidek, Z1
Hofer, M; Masek, K; Vacek, A1
Hofer, M; Juchelková, L; Masek, K; Pipalová, I; Vacek, A1
Bláha, L; Borkovcová, P; Masek, K; Thurnvaldová, J; Turánek, J; Vacek, A; Záluská, D1
Becker, PD; Corral, RS; Grinstein, S; Guzmán, CA1
Hofer, M; Hoferová, Z; Masek, K; Pipalová, I; Vacek, A; Weiterová, L1
Brejcha, A1
Becker, PD; Bertot, GM; Grinstein, S; Guzmán, CA1
Kasná, A; Knötigová, P; Masek, K; Turánek, J; Vacek, A; Záluská, D1
Becker, PD; Bertot, GM; Ebensen, T; Grinstein, S; Guzmán, CA; Souss, D1
Aranibar Urey, RC; Bertot, GM; Galanternik, L; Grinstein, S; Restelli, MA; Valvano, MA1
Becker, PD; Grinstein, S; Guzmán, CA; Nörder, M1

Reviews

2 review(s) available for adamantylamide-alanyl-isoglutamine and amantadine

ArticleYear
Antiviral and adjuvant activity of immunomodulator adamantylamide dipeptide.
    Advances in experimental medicine and biology, 1992, Volume: 319

    Topics: Adjuvants, Immunologic; Amantadine; Animals; Antibodies, Viral; Antiviral Agents; Dipeptides; Hypersensitivity, Delayed; Immunity, Cellular; Influenza Vaccines; Mice; Orthomyxoviridae Infections

1992
Current status and problems in preclinical assessment of immunomodulators.
    Developments in biological standardization, 1992, Volume: 77

    Topics: Acetylmuramyl-Alanyl-Isoglutamine; Adjuvants, Immunologic; Amantadine; Animals; Dipeptides; DNA Replication; Dose-Response Relationship, Immunologic; Drug Evaluation, Preclinical; Graft vs Host Reaction; Immunotherapy; Inflammation; Mice; Predictive Value of Tests; Reproducibility of Results; Sensitivity and Specificity; Structure-Activity Relationship; Thymidine Kinase

1992

Trials

1 trial(s) available for adamantylamide-alanyl-isoglutamine and amantadine

ArticleYear
Immune modulator adamantylamide dipeptide stimulates efficient major histocompatibility complex class I-restricted responses in mice.
    Clinical and vaccine immunology : CVI, 2007, Volume: 14, Issue:5

    Topics: Adjuvants, Immunologic; Amantadine; Animals; Antibody Formation; Antigens, Bacterial; CD8-Positive T-Lymphocytes; Dipeptides; Female; Genes, MHC Class I; Immunity, Cellular; Immunization; Interferon-gamma; Major Histocompatibility Complex; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL

2007

Other Studies

23 other study(ies) available for adamantylamide-alanyl-isoglutamine and amantadine

ArticleYear
Pharmacokinetic profile of the immunomodulating compound adamantylamide dipeptide (AdDP), a muramyl dipeptide derivative in mice.
    Immunopharmacology and immunotoxicology, 1991, Volume: 13, Issue:1-2

    Topics: Adjuvants, Immunologic; Amantadine; Animals; Dipeptides; Half-Life; Injections, Intravenous; Injections, Subcutaneous; Male; Metabolic Clearance Rate; Mice; Tissue Distribution

1991
The effect of some immunomodulators administration to rats on palmitic and oleic acids incorporation into the lipids of liver cell organelles.
    Methods and findings in experimental and clinical pharmacology, 1991, Volume: 13, Issue:4

    Topics: Acetylmuramyl-Alanyl-Isoglutamine; Amantadine; Animals; Cell Nucleus; Dipeptides; Levamisole; Lipids; Liver; Male; Oleic Acid; Oleic Acids; Organelles; Palmitic Acid; Palmitic Acids; Phospholipids; Rats; Rats, Inbred Strains; Subcellular Fractions; Tritium

1991
Effect of immunomodulator adamantylamide dipeptide on antibody response to influenza subunit vaccines and protection against aerosol influenza infection.
    Vaccine, 1990, Volume: 8, Issue:2

    Topics: Acetylmuramyl-Alanyl-Isoglutamine; Adjuvants, Immunologic; Aerosols; Aluminum Hydroxide; Amantadine; Animals; Antibodies, Viral; Cross Reactions; Dipeptides; Female; Hemagglutination Inhibition Tests; Influenza A virus; Influenza B virus; Influenza Vaccines; Mice; Orthomyxoviridae Infections; Vaccination

1990
The behavioural effects of benzodiazepine receptor ligands in mice are inhibited by adamantylamide dipeptide.
    Activitas nervosa superior, 1989, Volume: 31, Issue:4

    Topics: Adjuvants, Immunologic; Amantadine; Animals; Anxiety; Behavior, Animal; Carbolines; Diazepam; Dipeptides; Male; Mice; Receptors, GABA-A

1989
The immunomodulators levamisole, muramyl dipeptide and adamantylamide dipeptide antagonize the antianxiety effect of diazepam.
    Activitas nervosa superior, 1989, Volume: 31, Issue:2

    Topics: Acetylmuramyl-Alanyl-Isoglutamine; Aggression; Agonistic Behavior; Amantadine; Animals; Anti-Anxiety Agents; Diazepam; Dipeptides; Immune System; Levamisole; Male; Mice

1989
Immunomodulator adamantylamide dipeptide antagonizes benzodiazepine-induced rota-rod deficit in mice.
    Activitas nervosa superior, 1989, Volume: 31, Issue:4

    Topics: Adjuvants, Immunologic; Amantadine; Animals; Benzodiazepines; Dipeptides; Female; Mice; Movement Disorders

1989
Behavioural effects of muramyl dipeptide and adamantylamide dipeptide in mice.
    Activitas nervosa superior, 1989, Volume: 31, Issue:2

    Topics: Acetylmuramyl-Alanyl-Isoglutamine; Adjuvants, Immunologic; Aggression; Agonistic Behavior; Amantadine; Animals; Dipeptides; Immune System; Male; Mice

1989
Analgesic activity of two synthetic immunomodulators, muramyl dipeptide and adamantylamide dipeptide in mice and rats.
    Methods and findings in experimental and clinical pharmacology, 1988, Volume: 10, Issue:9

    Topics: Acetylmuramyl-Alanyl-Isoglutamine; Amantadine; Analgesics; Animals; Dipeptides; Fenclonine; Injections, Intraperitoneal; Injections, Intravenous; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Rats; Rats, Inbred Strains; Reaction Time; Species Specificity

1988
The immunomodulatory property of a novel synthetic compound adamantylamide dipeptide.
    Methods and findings in experimental and clinical pharmacology, 1984, Volume: 6, Issue:11

    Topics: Acetylmuramyl-Alanyl-Isoglutamine; Adjuvants, Immunologic; Amantadine; Animals; Chemical Phenomena; Chemistry; Dipeptides; DNA; Hypersensitivity, Delayed; Male; Ovalbumin; Rabbits; Rats; Rats, Inbred Strains

1984
Immune-related edemagenic activity of glutamines and glutamic acid, components of immunomodulatory agents.
    Agents and actions, 1994, Volume: 42, Issue:3-4

    Topics: Adjuvants, Immunologic; Amantadine; Amino Acid Sequence; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Dipeptides; Edema; Female; Glutamic Acid; Glutamine; Hemolytic Plaque Technique; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Structure-Activity Relationship

1994
Adjuvant effect of liposomes and adamantylamide dipeptide on antigenicity of entrapped synthetic peptide derived from HIV-1 transmembrane region glycoprotein gp41.
    Immunology letters, 1994, Volume: 39, Issue:2

    Topics: Adjuvants, Immunologic; Amantadine; Amino Acid Sequence; Animals; Dipeptides; Female; HIV Antibodies; HIV Antigens; HIV Envelope Protein gp41; HIV-1; Humans; Liposomes; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Peptides; Serum Albumin, Bovine; Vaccines, Synthetic

1994
T-cell-dependent immunobiological activity of a desmuramyl analog of muramyl dipeptide, adamantylamide dipeptide (AdDP), and D-isoglutamine.
    International journal of immunopharmacology, 1993, Volume: 15, Issue:5

    Topics: Adjuvants, Immunologic; Amantadine; Animals; Antilymphocyte Serum; Capillary Permeability; Dexamethasone; Dipeptides; Edema; Female; Glutamine; Indomethacin; Macrophages; Mice; Mice, Inbred C57BL; Stereoisomerism; T-Lymphocytes

1993
Effect of adamantylamide dipeptide on reinfection resistance after primary infection eradication in experimental Schistosomiasis mansoni.
    Arzneimittel-Forschung, 1996, Volume: 46, Issue:1

    Topics: Adjuvants, Immunologic; Amantadine; Animals; Antibody Formation; Antiplatyhelmintic Agents; Dipeptides; Drug Resistance; Granuloma; Immunity, Cellular; Liver; Lymphocytes; Mice; Mice, Inbred Strains; Praziquantel; Rats; Recurrence; Schistosomiasis mansoni; Schistosomicides

1996
Effects of in vivo administration of adamantylamide dipeptide on bone marrow granulocyte-macrophage hemopoietic progenitor cells (GM-CFC) and on ability of serum of the treated mice to stimulate GM-CFC colony formation in vitro: comparison with muramyl di
    Immunopharmacology and immunotoxicology, 1999, Volume: 21, Issue:1

    Topics: Acetylmuramyl-Alanyl-Isoglutamine; Adjuvants, Immunologic; Amantadine; Animals; Bone Marrow Cells; Cells, Cultured; Crosses, Genetic; Dipeptides; Glucans; Granulocytes; Hematopoietic Stem Cells; Immune Sera; Macrophages; Mice; Mice, Inbred C57BL; Mice, Inbred CBA

1999
Adamantylamide dipeptide stimulates hematopoiesis and increases survival in irradiated mice.
    International journal of immunopharmacology, 2000, Volume: 22, Issue:1

    Topics: Adjuvants, Immunologic; Amantadine; Animals; Dipeptides; Female; Hematopoiesis; Hematopoietic Stem Cells; Mice; Mice, Inbred C57BL; Mice, Inbred CBA

2000
Stimulation of nonspecific immunity, haemopoiesis and protection of mice against radiation injury by 1-adamantylamide-L-alanyl-D-isoglutamine incorporated in liposomes.
    International immunopharmacology, 2001, Volume: 1, Issue:1

    Topics: Adjuvants, Immunologic; Amantadine; Animals; Colony-Forming Units Assay; Dipeptides; Female; Hematopoiesis; Liposomes; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Radiation Injuries, Experimental

2001
Adamantylamide dipeptide as effective immunoadjuvant in rabbits and mice.
    Vaccine, 2001, Sep-14, Volume: 19, Issue:32

    Topics: Adjuvants, Immunologic; Administration, Oral; Amantadine; Animals; CpG Islands; Dipeptides; Dose-Response Relationship, Immunologic; Feces; Immunoglobulin A; Immunoglobulin G; Immunoglobulin Isotypes; Injections, Intraperitoneal; Lymphokines; Mice; Mice, Inbred BALB C; Mouth Mucosa; Ovalbumin; Rabbits; Species Specificity; Th2 Cells

2001
Hemopoiesis-stimulating action of adamantylamide dipeptide: kinetics of increase of GM-CFC in femur and co-stimulating activity of serum, role of bone marrow stromal cells.
    Immunopharmacology and immunotoxicology, 2001, Volume: 23, Issue:4

    Topics: Adjuvants, Immunologic; Amantadine; Animals; Bone Marrow Cells; Cell Cycle; Colony-Forming Units Assay; Culture Media, Conditioned; Dipeptides; Female; Femur; Granulocytes; Hematopoiesis; In Vitro Techniques; Injections, Intraperitoneal; Macrophages; Mice; Mice, Inbred Strains; Myeloid Progenitor Cells; Stromal Cells

2001
[Re the article by L. Peychl "Non-ulcerous stress changes in the duodenal mucosa"].
    Ceskoslovenska patologie, 2002, Volume: 38, Issue:4

    Topics: Amantadine; Animals; Dipeptides; Duodenum; Gastric Mucosa; Intestinal Mucosa; Rats; Rats, Wistar; Stress, Physiological

2002
Intranasal vaccination with recombinant P6 protein and adamantylamide dipeptide as mucosal adjuvant confers efficient protection against otitis media and lung infection by nontypeable Haemophilus influenzae.
    The Journal of infectious diseases, 2004, Apr-01, Volume: 189, Issue:7

    Topics: Adjuvants, Immunologic; Administration, Intranasal; Amantadine; Animals; Antibodies, Bacterial; Bacterial Outer Membrane Proteins; Bronchoalveolar Lavage Fluid; Dipeptides; Female; Haemophilus Infections; Haemophilus influenzae; Haemophilus Vaccines; Immunization; Lung Diseases; Mice; Mice, Inbred BALB C; Otitis Media; Recombinant Proteins; Saliva; Vagina

2004
Restoration of femoral GM-CFC progenitors in sublethally irradiated mice of various ages treated with liposomal adamantylamide dipeptide.
    International immunopharmacology, 2004, Volume: 4, Issue:8

    Topics: Aging; Amantadine; Animals; Cells, Cultured; Dipeptides; Dose-Response Relationship, Radiation; Female; Femur; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoiesis; Hematopoietic Stem Cells; Liposomes; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Radiation Injuries, Experimental; Radiation-Protective Agents

2004
Intranasal vaccination with recombinant outer membrane protein CD and adamantylamide dipeptide as the mucosal adjuvant enhances pulmonary clearance of Moraxella catarrhalis in an experimental murine model.
    Infection and immunity, 2007, Volume: 75, Issue:4

    Topics: Adhesins, Bacterial; Adjuvants, Immunologic; Administration, Intranasal; Amantadine; Animals; Antibodies, Bacterial; Bacterial Vaccines; Cell Proliferation; Colony Count, Microbial; Dipeptides; Disease Models, Animal; DNA, Bacterial; Immunoglobulin A, Secretory; Interferon-gamma; Interleukins; Lung; Lymphocytes; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Moraxella catarrhalis; Moraxellaceae Infections; Mucous Membrane; Spleen; Vaccines, Subunit; Vaccines, Synthetic

2007
Nasal immunization with Burkholderia multivorans outer membrane proteins and the mucosal adjuvant adamantylamide dipeptide confers efficient protection against experimental lung infections with B. multivorans and B. cenocepacia.
    Infection and immunity, 2007, Volume: 75, Issue:6

    Topics: Adjuvants, Immunologic; Administration, Intranasal; Amantadine; Animals; Antibodies, Bacterial; Bacterial Outer Membrane Proteins; Burkholderia cepacia complex; Burkholderia Infections; Dipeptides; Disease Models, Animal; Immunization; Lung Diseases; Mice; Mice, Inbred BALB C

2007