Page last updated: 2024-08-21

adamantane and rimantadine

adamantane has been researched along with rimantadine in 118 studies

Research

Studies (118)

Timeframe	Studies, this research(%)	All Research%
pre-1990	89 (75.42)	18.7374
1990's	7 (5.93)	18.2507
2000's	7 (5.93)	29.6817
2010's	13 (11.02)	24.3611
2020's	2 (1.69)	2.80

Authors

Authors	Studies
Knight, V; Koff, WC	1
Boissel, JP; Bricaire, F; Hannoun, C	1
Bruns, M; Ennis, FA; Herrmann, JE; West, K	2
Goreva, LN; Kirillov, VA; Votiakov, VI	1
Belshe, RB; Cerruti, RL; Connell, EV; Hill, CH; Keech, E; Manchand, PS; Martin, JA; Merrett, JH; Sim, IS	1
Dubrov, IuN; Gulak, PV; Leneva, IA; Sobolev, AS	1
Bubovich, VI; Indulen, MK; Ryazantseva, GM	1
Zhirnov, OP	1
Anisimova, E; Mikheeva, AV	1
Amvros'eva, TV; Erokhina, IR; Rusiaev, VA; Votiakov, VI	1
Choma, N; Fukuda, EK; Rubio, FA	1
Belshe, RB; Clover, RD; Hay, AJ; Hayden, FG; Oakes, MG; Soo, W	1
Betts, RF	1
Cherny, VV; Hessel, E; Lerche, D; Markin, VS; Paulitschke, M; Simonova, MV; Sokolov, VS	1
Brown, SY; Choma, N; Holazo, AA; Lee, LF; Wills, RJ	1
Blinov, VM; Burmistrova, VV; Golubev, DB; Karginov, VA; Kozeletskaia, KN; Siniakov, AN	1
Akopova, II; Gorodkova, NV; Indulen, MK; Kalninya, VA	1
Bentley, DW; Betts, RF; Karki, SD	1
Belshe, RB; Burk, B; Cerruti, RL; Newman, F; Sim, IS	1
Choma, N; De Grazia, F; Fukuda, EK; Garland, WA; Keigher, N; Rodriguez, LC	1
Kubar', OI; Shvetsova, EG; Zlydnikov, DM	1
Donath, E; Donath, J; el-Karadagi, S; Glaser, R; Herrmann, A; Kharitonenkov, IG; Lentzsch, P; Tverdislov, VA	1
Coakley, WT; Donath, E; Egger, M; Groth, T; Herrmann, A; Taeger, M	1
Donath, E; Egger, M; Glaser, R; Ziemer, S	1
Brown, SY; Choma, N; Fukuda, EK; Garland, WA; Keigher, N; Miwa, BJ	1
Gustavson, LE; Hayden, FG; Tominack, RL; Wills, RJ	1
Blasecki, JW; Gaylord, JC; Hoffman, HE; Shalaby, LM; Whitney, CC	1
Belshe, RB; Betts, R; Hall, CB; Hay, AJ; Smith, MH	1
Abell, TD; Clover, RD; Couch, RB; Crawford, SA; Glezen, P; Ramsey, CN	1
Disney, FA; Dolin, R; Francis, AB; Gala, CL; Green, JL; Hall, CB; Madore, PH; Markovitz, DM; Talpey, WB; Zhang, YQ	1
Hayden, FG; Tominack, RL	1
Spector, R	1
Capparelli, EV; Chow, MS; Izard, M; Stevens, RC; Wills, RJ	1
Anonick, PK; Hayden, FG; Herold, DA; Kinter, M	1
Choma, N; Oakes, M; Rodriguez, LC; Wills, RJ	1
Buonpane, G; Choma, N; Keigher, N; Lin, A; Wills, RJ	1
Blinov, VM; Golovin, SIa; Karginov, VA; Mamaev, LV; Safronov, PF	1
Abell, TD; Clover, RD; Couch, RB; Crawford, SA; Glezen, WP; Ramsey, CN	1
Hayden, FG; Monto, AS	1
Fleet, W; Lawrence, E; Morris, L; Pierce, E; Thompson, J; Wright, P	1
Gegova, G; Maksimova-Todorova, V; Manolova, N; Serkedzhieva, Iu	1
Choma, N; Farolino, DA; Keigher, N; Wills, RJ	1
Kirillov, VA; Podol'skaia, IA; Sudnik, IuM; Votiakov, VI	1
Anderson, EL; Bartram, J; Belshe, RB; Hoffman, HE; Van Voris, LP	1
Belshe, R; Berry, C; De Grazia, F; Lin, A; Milazzo, J; Tomlinsin, D; Wells, S; Wills, RJ	1
Bukrinskaia, AG; Chaĭka, OV; Moĭsiadi, SA; Shilov, AA; Zhdanov, VM	1
Brady, MT; Nahata, MC	1
Jannasch, R	1
Bean, WJ; Kawaoka, Y; Webster, RG	1
Hayden, FG; Hoffman, HE; Minocha, A; Spyker, DA	1
Enokhin, SF; Filev, LV; Medvedev, IuV; Popov, VG; Volchek, IV	1
Galegov, GA; Petrova, IG; Pravdina, NF; Shobukhov, VM; Tul'kes, SG	1
Bean, WJ; Beard, CW; Brugh, M; Kawaoka, Y; Webster, RG	1
Döhner, L; Mentel, R; Panzig, B; Seidel, W	1
Kochemasova, ZN; Lvov, ND; Pushkarskaya, NL	1
Adamczyk, B; Feldblum, R; Heider, H; Indulen, MK; Presber, HW; Schroeder, C	1
Golubev, DB; Kozeletskaya, KN; Yukhnova, LG	1
Aspetov, RD; Nosik, DN; Novokhatskiĭ, AS	1
Yaar, I	1
Efremov, BV; Erofeeva, MK; Ignat'eva, GS; Maksakova, VL; Malysheva, AM	1
Araslanova, II; Gagarinova, VM; Kubar', OI; Kustikova, IuG; Shadrin, AS	1
Bigimbetova, ShSh; Smagulov, KZ; Smagulova, EG	1
Gorenskaia, RL; Kubar', OI; Leonov, VM; Romanov, IuA; Rumel', NB	1
Gorenskaia, RA; Kubar', OI; Padalko, IuV; Reĭkh, LIa; Romanov, IuA	1
Kubar', OI; Romanov, IuA; Rumen', NB; Vasilevskaia, NM; Zherbina, LA	1
Bregman, DJ; Kater, NA; Kendal, AP; Patriarca, PA; Sikes, RK; Smith, JD	1
Bucher, DJ; El Karadaghi, S; Kharitonenkov, IG; Tverdislov, VA; Zakomirdin, JA	1
Błoch, P; Denys, A; Korczak, E; Kulig, A; Sygut, J	1
Erofeeva, MK; Shadrin, AS	1
Sebastiani, A	1
Garcia Gil, M; Sanchez Crespo, M	1
Elm, JL; Halstead, SB; Koff, WC; Pratt, RD; Venkateshan, CN	1
Hayden, FG; Pushkarskaya, NL; Schlepushkin, AN	1
Hayden, FG; Hoffman, HE; Spyker, DA	1
Ghendon, YZ; Zvonarjev, AY	1
Bryson, YJ; Dreisbach, M; Millet, VM	1
Dolin, R; Linton, PN; Madore, HP; Maynard, R; Reichman, RC; Webber-Jones, J	1
Bukrinskaya, AG; Kornilayeva, GV; Narmanbetova, RA; Vorkunova, GK; Vorkunova, NK	1
Bukrinskaya, AG; Pushkarskaya, NL; Vorkunova, NK	1
Burlington, DB; Meiklejohn, G; Mostow, SR	2
Aleksandrov, BA; Anisimov, WN; Likhachev, AIa; Okulov, VB; Pozharisskiĭ, KM	1
Hayden, FG; Iljenko, VI; Padolka, YV; Zylidnikov, DM	1
Erofeeva, MK; Lugovskaia, VP; Malysheva, AM; Oleĭnikova, EV; Shadrin, AS	1
Galegov, GA; Iatsyna, AA	1
Elm, JL; Halstead, SB; Koff, WC	1
Geĭker, VI; Romanov, IuA; Rumel', NB; Vasilevskaia, NM; Zlydnikov, DM	1
Zlydnikov, DM	2
Cate, TR; Couch, RB; Goswick, CB; Quarles, JM	1
Adams, KF; Giordani, B; Gwaltney, JM; Hayden, FG; Van de Castle, RL	1
Bukrinskaya, AG; Narmanbetova, RA; Vorkunova, NK	1
Andronova, VL	2
Lu, Q	1
Barr, IG; Deed, N; Hurt, AC; Iannello, P; Komadina, N; Tomasov, C	2
Kelly, JM; Kolocouris, N; Papanastasiou, I; Prathalingam, SR; Tsotinis, A	1
De Clercq, E; Kolocouris, N; Naesens, L; Zoidis, G	1
Chou, KC; Wang, JF; Wei, DQ	1
Abughali, N; Abzug, MJ; Bradley, JS; Cloud, GA; Englund, J; Griffin, J; Guzman-Cottrill, J; Jacobs, RF; Jester, P; Kimberlin, DW; Lang, D; Leach, C; Ramilo, O; Robinson, J; Romero, JR; Shalabi, M; Shelton, M; Storch, G; Wade, KC; Whitley, RJ	1
Chou, KC; Du, QS; Huang, RB; Wang, SQ	1
Arkin, IT; Astrahan, P	1
Beekmann, SE; Dharan, NJ; Finelli, L; Fiore, A; Fry, AM; Polgreen, PM; Uyeki, TM	1
Dong, L; Gao, Y; Guo, J; Guo, Y; Huang, W; Jiang, T; Lan, Y; Li, X; Li, Z; Peng, Y; Shu, Y; Wang, D; Wang, M; Wang, W; Wen, L; Xin, L; Xu, C; Yang, L; Zhang, Y; Zhao, X	1
Arkin, IT; Astrahan, P; Krugliak, M; Leonov, H	1
Rohde, GG	1
Burtseva, EI; Finogenova, MP; Garaev, TM; Shevchenko, ES; Shibnev, VA	1
Berardi, MJ; Chou, JJ; Dev, J; OuYang, B; Sun, B; Xie, S; Yu, W; Zhao, X	1
Busath, DD; Cross, TA; Fedida, D; Johnson, FB; Kolocouris, A; Tietjen, I; Tzitzoglaki, C; Wright, AK; Zell, R	1
Botikov, AG; Deryabin, PG; Finogenova, MP; Garaev, TM; Shibnev, VA	1
Bubnov, YN; Burtseva, EI; Godovikov, IA; Kirillova, ES; Kuznetsov, NY; Lyssenko, KA; Medvedev, MG; Tikhov, RM	1
Boeckler, FM; Breitinger, HG; Breitinger, U; Ma, C; Mandour, YM; Wang, J; Zlotos, DP	1
Chatziathanasiadou, MV; Chayrov, R; Mavromoustakos, T; Melagraki, G; Mitrev, Y; Moschovou, K; Parisis, NA; Sbirkova-Dimitrova, H; Schmidtke, M; Shivachev, B; Stankova, I; Sticha, M; Tzakos, AG; Vrontaki, E	1
Barchanska, H; Kostina-Bednarz, M; Płonka, J	1

Reviews

4 review(s) available for adamantane and rimantadine

Article	Year
Amantadine and rimantadine for the prevention of influenza A. Seminars in respiratory infections, 1989, Volume: 4, Issue:4 Topics: Adamantane; Adult; Age Factors; Aged; Amantadine; Child; Humans; Influenza A virus; Influenza, Human; Rimantadine; Seasons; United States	1989
Rimantadine hydrochloride and amantadine hydrochloride use in influenza A virus infections. Infectious disease clinics of North America, 1987, Volume: 1, Issue:2 Topics: Adamantane; Adult; Aged; Amantadine; Humans; Influenza A virus; Influenza, Human; Rimantadine	1987
Antiviral therapy and prophylaxis for influenza in children. Pediatrics, 2007, Volume: 119, Issue:4 Topics: Adamantane; Amantadine; Antiviral Agents; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Infant; Influenza, Human; Male; Oseltamivir; Primary Prevention; Prospective Studies; Randomized Controlled Trials as Topic; Rimantadine; Risk Assessment; Severity of Illness Index; Treatment Outcome; Zanamivir	2007
Resistance characteristics of influenza to amino-adamantyls. Biochimica et biophysica acta, 2011, Volume: 1808, Issue:2 Topics: Adamantane; Amantadine; Amino Acid Sequence; Drug Resistance, Viral; Genes, Viral; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Influenza A virus; Influenza, Human; Ion Channels; Models, Molecular; Molecular Sequence Data; Mutation; Protein Stability; Protein Structure, Tertiary; Rimantadine; Sequence Homology, Amino Acid; Viral Matrix Proteins	2011

Trials

18 trial(s) available for adamantane and rimantadine

Article	Year
[Prevention of influenza A. Effectiveness and tolerance of rimantadine hydrochloride]. Presse medicale (Paris, France : 1983), 1990, Jan-20, Volume: 19, Issue:2 Topics: Adamantane; Clinical Trials as Topic; Drug Evaluation; Female; France; Humans; Influenza A virus; Influenza, Human; Male; Placebos; Premedication; Rimantadine	1990
Emergence and apparent transmission of rimantadine-resistant influenza A virus in families. The New England journal of medicine, 1989, Dec-21, Volume: 321, Issue:25 Topics: Adamantane; Administration, Oral; Adolescent; Adult; Aged; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Drug Resistance, Microbial; Female; Humans; Infant; Influenza A virus; Influenza, Human; Male; Middle Aged; Random Allocation; Rimantadine	1989
Genetic basis of resistance to rimantadine emerging during treatment of influenza virus infection. Journal of virology, 1988, Volume: 62, Issue:5 Topics: Adamantane; Amino Acid Sequence; Base Sequence; Clinical Trials as Topic; Drug Resistance, Microbial; Humans; Influenza A virus; Influenza, Human; Molecular Sequence Data; Rimantadine	1988
Rimantadine prophylaxis in children: a follow-up study. The Pediatric infectious disease journal, 1988, Volume: 7, Issue:6 Topics: Adamantane; Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Drug Tolerance; Follow-Up Studies; Humans; Infant; Influenza, Human; Lung Diseases, Obstructive; Rimantadine; Risk Factors	1988
Children with influenza A infection: treatment with rimantadine. Pediatrics, 1987, Volume: 80, Issue:2 Topics: Acetaminophen; Adamantane; Adolescent; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Infant; Influenza, Human; Male; Random Allocation; Rimantadine	1987
Relative bioavailability of rimantadine HCl tablet and syrup formulations in healthy subjects. Journal of pharmaceutical sciences, 1987, Volume: 76, Issue:12 Topics: Adamantane; Adolescent; Adult; Biological Availability; Humans; Male; Rimantadine; Solutions; Tablets	1987
Effectiveness of rimantadine prophylaxis of children within families. American journal of diseases of children (1960), 1986, Volume: 140, Issue:7 Topics: Adamantane; Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Infant; Influenza A virus; Influenza B virus; Influenza, Human; Male; Office Visits; Patient Compliance; Random Allocation; Rimantadine	1986
Oral rimantadine hydrochloride therapy of influenza A virus H3N2 subtype infection in adults. Antimicrobial agents and chemotherapy, 1986, Volume: 29, Issue:2 Topics: Adamantane; Administration, Oral; Adult; Body Temperature; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Influenza A virus; Influenza A Virus, H3N2 Subtype; Influenza, Human; Male; Nasal Mucosa; Random Allocation; Rimantadine	1986
A comparison of acetaminophen and rimantadine in the treatment of influenza A infection in children. Journal of medical virology, 1987, Volume: 21, Issue:3 Topics: Acetaminophen; Adamantane; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Humans; Infant; Influenza A virus; Influenza, Human; Random Allocation; Rimantadine	1987
Rimantadine pharmacokinetics after single and multiple doses. Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:5 Topics: Adamantane; Adolescent; Adult; Drug Administration Schedule; Humans; Kinetics; Male; Random Allocation; Rimantadine	1987
Comparative single-dose pharmacokinetics of amantadine hydrochloride and rimantadine hydrochloride in young and elderly adults. Antimicrobial agents and chemotherapy, 1985, Volume: 28, Issue:2 Topics: Adamantane; Adult; Aged; Amantadine; Female; Humans; Kinetics; Male; Metabolic Clearance Rate; Mucus; Nasal Mucosa; Rimantadine	1985
[Evaluation of rimantadine effectiveness during influenza A2-Texas epidemic in 1979-1980]. Klinicheskaia meditsina, 1981, Volume: 59, Issue:2 Topics: Adamantane; Clinical Trials as Topic; Disease Outbreaks; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Influenza A virus; Influenza, Human; Rimantadine; Russia	1981
Safety of prolonged administration of rimantadine hydrochloride in the prophylaxis of influenza A virus infections in nursing homes. Antimicrobial agents and chemotherapy, 1984, Volume: 26, Issue:1 Topics: Adamantane; Cross Infection; Humans; Influenza A virus; Influenza, Human; Nursing Homes; Rimantadine; Time Factors	1984
Differences in side effects of amantadine hydrochloride and rimantadine hydrochloride relate to differences in pharmacokinetics. Antimicrobial agents and chemotherapy, 1983, Volume: 23, Issue:3 Topics: Adamantane; Adult; Amantadine; Central Nervous System; Digestive System; Humans; Kinetics; Middle Aged; Rimantadine; Sleep	1983
Double-blind controlled study of central nervous system side effects of amantadine, rimantadine, and chlorpheniramine. Antimicrobial agents and chemotherapy, 1982, Volume: 21, Issue:1 Topics: Adamantane; Adolescent; Adult; Amantadine; Central Nervous System; Chlorpheniramine; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Rimantadine	1982
A controlled trial of amantadine and rimantadine in the prophylaxis of influenza A infection. The New England journal of medicine, 1982, Sep-02, Volume: 307, Issue:10 Topics: Adamantane; Adolescent; Adult; Amantadine; Clinical Trials as Topic; Humans; Infant, Newborn; Influenza A virus; Influenza, Human; Middle Aged; Patient Compliance; Random Allocation; Rimantadine	1982
Comparative therapeutic effect of aerosolized and oral rimantadine HCl in experimental human influenza A virus infection. Antiviral research, 1982, Volume: 2, Issue:3 Topics: Adamantane; Administration, Oral; Aerosols; Female; Fever; Humans; Influenza, Human; Male; Rimantadine	1982
Comparative toxicity of amantadine hydrochloride and rimantadine hydrochloride in healthy adults. Antimicrobial agents and chemotherapy, 1981, Volume: 19, Issue:2 Topics: Adamantane; Adult; Amantadine; Central Nervous System Diseases; Gastrointestinal Diseases; Humans; Motor Skills; Rimantadine; Sleep Wake Disorders; Time Factors	1981

Other Studies

96 other study(ies) available for adamantane and rimantadine

Article	Year
Inhibition of influenza virus uncoating by rimantadine hydrochloride. Journal of virology, 1979, Volume: 31, Issue:1 Topics: Adamantane; Adsorption; Animals; Cell Line; Dogs; Influenza A virus; Kidney; Ribonucleases; Rimantadine; Virus Replication	1979
Effect of rimantadine on cytotoxic T lymphocyte responses and immunity to reinfection in mice infected with influenza A virus. The Journal of infectious diseases, 1990, Volume: 161, Issue:2 Topics: Adamantane; Animals; Antibodies, Viral; Influenza A virus; Male; Mice; Mice, Inbred BALB C; Orthomyxoviridae Infections; Recurrence; Rimantadine; T-Lymphocytes, Cytotoxic	1990
[Role of the cellular Na+/H+ exchange and glycolysis inhibition by the antiviral action]. Biulleten' eksperimental'noi biologii i meditsiny, 1990, Volume: 109, Issue:1 Topics: Adamantane; Animals; Cells, Cultured; Chick Embryo; Culture Media; Fibroblasts; Glycolysis; Hydrogen-Ion Concentration; Ion Exchange; Lactates; Rimantadine; Sodium	1990
Synthesis and antiviral activity of metabolites of rimantadine. Journal of medicinal chemistry, 1990, Volume: 33, Issue:7 Topics: Adamantane; Animals; Antiviral Agents; Cell Line; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microbial Sensitivity Tests; Molecular Structure; Rimantadine; Structure-Activity Relationship	1990
[Effects of remantadine on fusion of lipid membranes of influenza A virus with plasma and internal membranes of lymphoblastic cells]. Biulleten' eksperimental'noi biologii i meditsiny, 1990, Volume: 109, Issue:5 Topics: Adamantane; Animals; Cell Line; Cell Membrane; Chick Embryo; Endocytosis; Fluorescent Dyes; Hydrogen-Ion Concentration; Influenza A virus; Membrane Lipids; Rimantadine	1990
Deproteinization of influenza virus in the presence of rimantadine. Acta virologica, 1985, Volume: 29, Issue:2 Topics: Adamantane; Animals; Azauridine; Chick Embryo; Cycloheximide; Orthomyxoviridae; Rimantadine; RNA, Viral; Viral Proteins	1985
High protection of animals lethally infected with influenza virus by aprotinin-rimantadine combination. Journal of medical virology, 1987, Volume: 21, Issue:2 Topics: Adamantane; Animals; Aprotinin; Drug Combinations; Drug Synergism; Influenza A virus; Lung; Mice; Orthomyxoviridae Infections; Rimantadine	1987
Action of rimantadine on the structure of influenza A virus haemagglutinin. Acta virologica, 1989, Volume: 33, Issue:2 Topics: Adamantane; Animals; Chick Embryo; Hemagglutinin Glycoproteins, Influenza Virus; Hemagglutinins, Viral; Hydrogen-Ion Concentration; Influenza A virus; Membrane Fusion; Protein Conformation; Rimantadine; Trypsin; Virion	1989
[Pathology of the reproductive apparatus of cells under the action of remantadine and deitiforin]. Biulleten' eksperimental'noi biologii i meditsiny, 1989, Volume: 108, Issue:9 Topics: Adamantane; Animals; Antiviral Agents; Cell Division; Cells, Cultured; Dogs; Dose-Response Relationship, Drug; Kidney; Mitosis; Organic Chemicals; Rimantadine; Time Factors	1989
Determination of rimantadine and its hydroxylated metabolites in human plasma and urine. Journal of chromatography, 1989, Dec-29, Volume: 497 Topics: Adamantane; Gas Chromatography-Mass Spectrometry; Humans; Hydroxylation; Rimantadine	1989
Efficacy of rimantadine hydrochloride in the treatment of influenza infection of mice. Antiviral research, 1989, Volume: 11, Issue:3 Topics: Adamantane; Administration, Oral; Animals; Disease Models, Animal; Influenza A virus; Injections, Intraperitoneal; Lung; Male; Mice; Mice, Inbred BALB C; Orthomyxoviridae Infections; Rimantadine	1989
The effect of rimantadine on the structure of model and biological membranes. General physiology and biophysics, 1989, Volume: 8, Issue:1 Topics: Adamantane; Cell Aggregation; Electric Conductivity; Erythrocyte Deformability; Erythrocyte Membrane; Erythrocytes; Humans; In Vitro Techniques; Lipid Bilayers; Lipids; Mathematics; Membrane Fluidity; Membrane Potentials; Models, Theoretical; Phosphatidylcholines; Phospholipids; Rimantadine	1989
Effect of cimetidine on the disposition of rimantadine in healthy subjects. Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:6 Topics: Adamantane; Adult; Cimetidine; Drug Interactions; Female; Half-Life; Humans; Male; Middle Aged; Rimantadine	1989
[The change in functional activity and primary structure of the M2 protein in variants of the influenza virus resistant to remantadine and deitiforin: common and individual differences from the original strain]. Molekuliarnaia genetika, mikrobiologiia i virusologiia, 1989, Issue:6 Topics: Adamantane; Amino Acid Sequence; Antiviral Agents; Base Sequence; Drug Resistance, Microbial; Genes, Viral; Influenza A virus; Molecular Sequence Data; Organic Chemicals; Protein Conformation; Rimantadine; Viral Matrix Proteins	1989
Virion transcriptase activity of rimantadine-sensitive and rimantadine-resistant variants of human influenza virus. Acta virologica, 1987, Volume: 31, Issue:6 Topics: Adamantane; Animals; Cells, Cultured; Chick Embryo; DNA-Directed RNA Polymerases; Drug Resistance, Microbial; Fibroblasts; Genes, Viral; Humans; Influenza A virus; Ribonucleoproteins; Rimantadine; RNA, Viral; Viral Proteins; Virion	1987
Rimantadine and seizures. Annals of internal medicine, 1989, Feb-15, Volume: 110, Issue:4 Topics: Adamantane; Adult; Aged; Aged, 80 and over; Anticonvulsants; Humans; Influenza, Human; Male; Rimantadine; Seizures	1989
Resistance of influenza A virus to amantadine and rimantadine: results of one decade of surveillance. The Journal of infectious diseases, 1989, Volume: 159, Issue:3 Topics: Adamantane; Amantadine; Animals; Antigens, Viral; Cell Line; Cytopathogenic Effect, Viral; Dogs; Drug Resistance; Enzyme-Linked Immunosorbent Assay; Humans; Influenza A virus; Influenza, Human; Rimantadine; Viral Plaque Assay	1989
Quantitative determination of rimantadine in human plasma and urine by GC-MS. Biomedical & environmental mass spectrometry, 1987, Volume: 14, Issue:10 Topics: Adamantane; Chromatography, Gas; Drug Stability; Electrochemistry; Gas Chromatography-Mass Spectrometry; Humans; Rimantadine	1987
[Principles of the use of anti-influenza drugs]. Terapevticheskii arkhiv, 1988, Volume: 60, Issue:8 Topics: Adamantane; Ambulatory Care; Disease Outbreaks; Drug Administration Schedule; Humans; Influenza, Human; Rimantadine; Russia	1988
Interaction of the antivirus agents remantadine and amantadine with lipid membranes and the influence on the curvature of human red cells. General physiology and biophysics, 1986, Volume: 5, Issue:1 Topics: Adamantane; Amantadine; Elasticity; Electron Spin Resonance Spectroscopy; Erythrocyte Deformability; Humans; Intracellular Membranes; Membrane Lipids; Rimantadine; Time Factors	1986
The influence of the antiviral drugs amantadine and rimantadine on erythrocyte and platelet membranes and its comparison with that of tetracaine. Biochemical pharmacology, 1987, Feb-15, Volume: 36, Issue:4 Topics: Adamantane; Amantadine; Antiviral Agents; Blood Platelets; Cell Fractionation; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Hemagglutination, Viral; Humans; Osmotic Fragility; Platelet Aggregation; Rimantadine; Tetracaine	1987
Electrorotation--a new method for investigating membrane events during thrombocyte activation. Influence of drugs and osmotic pressure. Biochimica et biophysica acta, 1986, Sep-25, Volume: 861, Issue:1 Topics: Adamantane; Amantadine; Blood Platelets; Calcimycin; Cell Membrane; Chlorpromazine; Electrochemistry; Humans; Light; Mathematics; Osmotic Pressure; Platelet Aggregation; Rimantadine; Scattering, Radiation; Thrombin	1986
Quantitation of the enantiomers of rimantadine in human plasma and urine by gas chromatography-mass spectrometry. Journal of chromatography, 1988, Oct-14, Volume: 431, Issue:2 Topics: Adamantane; Adult; Gas Chromatography-Mass Spectrometry; Glucuronidase; Humans; Indicators and Reagents; Male; Models, Biological; Multienzyme Complexes; Rimantadine; Stereoisomerism; Sulfatases	1988
Multiple-dose pharmacokinetics of rimantadine in elderly adults. Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:12 Topics: Adamantane; Administration, Oral; Age Factors; Aged; Aging; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Rimantadine	1988
Pharmacokinetics and metabolism of rimantadine hydrochloride in mice and dogs. Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:11 Topics: Adamantane; Administration, Oral; Amantadine; Animals; Biological Availability; Dogs; Dose-Response Relationship, Drug; Feces; Female; Gas Chromatography-Mass Spectrometry; Lung; Metabolic Clearance Rate; Mice; Orthomyxoviridae Infections; Rimantadine	1988
Transport of amantadine and rimantadine through the blood-brain barrier. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 244, Issue:2 Topics: Adamantane; Amantadine; Animals; Biological Transport; Blood-Brain Barrier; Perfusion; Rats; Rats, Inbred Strains; Rimantadine	1988
Rimantadine pharmacokinetics in healthy subjects and patients with end-stage renal failure. Clinical pharmacology and therapeutics, 1988, Volume: 43, Issue:5 Topics: Adamantane; Adult; Aged; Female; Humans; Kidney Failure, Chronic; Male; Metabolic Clearance Rate; Middle Aged; Renal Dialysis; Rimantadine	1988
Measurement of rimantadine in plasma by capillary gas chromatography/mass spectrometry with a deuterium-labeled internal standard. Clinical chemistry, 1988, Volume: 34, Issue:8 Topics: Adamantane; Deuterium; Gas Chromatography-Mass Spectrometry; Humans; Rimantadine	1988
Influence of a meal on the bioavailability of rimantadine.HCl. Journal of clinical pharmacology, 1987, Volume: 27, Issue:10 Topics: Adamantane; Adult; Biological Availability; Eating; Female; Humans; Male; Rimantadine	1987
[Comparative analysis of primary structure of M-genes in remantadine-resistant and remantadine-sensitive strains of influenza virus A/FPV/Weybridge (H7N7) strains]. Bioorganicheskaia khimiia, 1987, Volume: 13, Issue:12 Topics: Adamantane; Amino Acid Sequence; Animals; Base Sequence; Chick Embryo; DNA; DNA, Viral; Drug Resistance, Microbial; Genes, Viral; Influenza A virus; Influenza A Virus, H7N7 Subtype; Molecular Sequence Data; Rimantadine; Viral Proteins	1987
[Combined action of antiviral substances of natural and synthetic origin. I. The anti-influenza action of a combination of the polyphenol complex isolated from Geranium sanguineum L. and remantadine in vitro and in ovo]. Acta microbiologica Bulgarica, 1986, Volume: 19 Topics: Adamantane; Animals; Antiviral Agents; Chick Embryo; Culture Techniques; Drug Evaluation, Preclinical; Drug Therapy, Combination; Flavonoids; Influenza A virus; Orthomyxoviridae Infections; Phenols; Plants, Medicinal; Polymers; Polyphenols; Rimantadine; Virus Replication	1986
[Inhibition by remantadine of the influenza virus-induced reduction in the rate of osmotic lysis of chicken erythrocytes]. Doklady Akademii nauk SSSR, 1987, Volume: 295, Issue:4 Topics: Adamantane; Animals; Chickens; Culture Techniques; Erythrocytes; Hemolysis; Orthomyxoviridae; Rimantadine; Virus Cultivation	1987
Pharmacokinetics of a single dose of rimantadine in young adults and children. Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:7 Topics: Adamantane; Administration, Oral; Adult; Child; Child, Preschool; Half-Life; Humans; Kinetics; Male; Random Allocation; Rimantadine; Solutions; Tablets	1987
Pharmacokinetics of rimantadine hydrochloride in patients with chronic liver disease. Clinical pharmacology and therapeutics, 1987, Volume: 42, Issue:4 Topics: Adamantane; Adult; Aged; Chronic Disease; Female; Half-Life; Humans; Liver Diseases; Male; Middle Aged; Rimantadine	1987
[Remantadine-resistant and remantadine-sensitive variants of the influenza virus have different structures of hemagglutinin and matrix protein genes]. Doklady Akademii nauk SSSR, 1986, Volume: 289, Issue:5 Topics: Adamantane; Drug Resistance, Microbial; Genes, Viral; Glycoproteins; Hemagglutinins, Viral; Influenza A virus; Rimantadine	1986
Serum concentrations and safety of rimantadine in paediatric patients. European journal of clinical pharmacology, 1986, Volume: 30, Issue:6 Topics: Adamantane; Dose-Response Relationship, Drug; Hematuria; Humans; Infant; Rimantadine; Time Factors	1986
[Capillary isotachophoresis--a new method in drug analysis. 3. Analytic capillary isotachophoresis for the determination of amantadine and rimantadine]. Die Pharmazie, 1986, Volume: 41, Issue:7 Topics: Adamantane; Amantadine; Capsules; Electrophoresis; Rimantadine; Spectrophotometry, Ultraviolet; Tablets	1986
Vaccination as a strategy to reduce the emergence of amantadine- and rimantadine-resistant strains of A/Chick/Pennsylvania/83 (H5N2) influenza virus. The Journal of antimicrobial chemotherapy, 1986, Volume: 18 Suppl B Topics: Adamantane; Amantadine; Animals; Drug Resistance, Microbial; Influenza A virus; Influenza A Virus, H5N2 Subtype; Influenza Vaccines; Orthomyxoviridae Infections; Poultry; Poultry Diseases; Rimantadine; Vaccination	1986
[Effect of interlok, remantadine and biotop on normal monocyte functional activity and in acute viral hepatitis]. Zhurnal mikrobiologii, epidemiologii i immunobiologii, 1985, Issue:11 Topics: Acute Disease; Adamantane; Cells, Cultured; Drug Combinations; Drug Evaluation, Preclinical; Hepatitis A; Hepatitis B; Humans; Interferon Type I; Monocytes; Nitroblue Tetrazolium; Polymers; Rimantadine; Viremia	1985
Current status of amantadine and rimantadine as anti-influenza-A agents: memorandum from a WHO meeting. Bulletin of the World Health Organization, 1985, Volume: 63, Issue:1 Topics: Adamantane; Amantadine; Humans; Influenza A virus; Influenza, Human; Rimantadine	1985
[Kinetics of 3H-remantadine accumulation and excretion in the tissues of pregnant mice and their fetuses]. Biulleten' eksperimental'noi biologii i meditsiny, 1985, Volume: 99, Issue:1 Topics: Adamantane; Animals; Female; Fetus; Half-Life; Kinetics; Mice; Pregnancy; Pregnancy, Animal; Rimantadine; Time Factors; Tissue Distribution; Tritium	1985
Chemotherapy and vaccination: a possible strategy for the control of highly virulent influenza virus. Journal of virology, 1985, Volume: 55, Issue:1 Topics: Adamantane; Amantadine; Animals; Chickens; Drug Resistance, Microbial; Influenza A virus; Influenza in Birds; Rimantadine; Vaccination; Viral Vaccines	1985
[Action of antiviral substances on influenza viruses through the inhibition of neuraminidase production]. Archiv fur experimentelle Veterinarmedizin, 1985, Volume: 39, Issue:3 Topics: Adamantane; Amantadine; Animals; Chick Embryo; Culture Techniques; Fibroblasts; Influenza A virus; Neuraminidase; Rimantadine	1985
Comparative study on the inhibitory effect of rimantadine on the reproduction of epidemic strains of influenza A virus H3N2 and H1N1. Acta virologica, 1981, Volume: 25, Issue:5 Topics: Adamantane; Animals; Cell Line; Cytopathogenic Effect, Viral; Dogs; Influenza A virus; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Rimantadine	1981
Occurrence of amantadine- and rimantadine-resistant influenza A virus strains during the 1980 epidemic. Acta virologica, 1981, Volume: 25, Issue:6 Topics: Adamantane; Amantadine; Drug Resistance, Microbial; Humans; Influenza A virus; Mutation; Rimantadine	1981
Characterization of the effect of rimantadine on intracellular distribution and transport into the nuclei of infected cells of the parent influenza virus genome. Acta virologica, 1984, Volume: 28, Issue:6 Topics: Adamantane; Animals; Biological Transport; Cell Compartmentation; Cell Nucleus; Cells, Cultured; Dogs; Influenza A virus; Rimantadine; Transcription, Genetic; Viral Proteins; Virus Replication	1984
[Effect of remantadine and ribavirin on the production and antiviral action of human interferon types I and II]. Antibiotiki, 1982, Volume: 27, Issue:1 Topics: Adamantane; Animals; Antiviral Agents; Cells, Cultured; Chick Embryo; Humans; Interferon Inducers; Interferons; Ribavirin; Ribonucleosides; Rimantadine; Semliki forest virus; Vesicular stomatitis Indiana virus	1982
The effects of amantadine, rimantadine and levodopa on the frequency of fibrillation potentials in denervated muscle. Electroencephalography and clinical neurophysiology, 1984, Volume: 57, Issue:2 Topics: Acetylcholine; Adamantane; Amantadine; Animals; Electromyography; Levodopa; Muscle Contraction; Muscle Denervation; Rats; Receptors, Cholinergic; Rimantadine	1984
[Combined prevention of influenza using inactivated influenza vaccine and remantadine in organized collectives of adults]. Trudy Instituta imeni Pastera, 1982, Volume: 57 Topics: Adamantane; Adult; Disease Outbreaks; Drug Evaluation; Humans; Influenza Vaccines; Influenza, Human; Rimantadine; Russia; Vaccines, Attenuated	1982
[Organization and evaluation of the effectiveness of emergency prophylaxis and early treatment of influenza with remantadine in Serevodvinsk]. Zhurnal mikrobiologii, epidemiologii i immunobiologii, 1983, Issue:3 Topics: Adamantane; Adult; Drug Evaluation; Emergencies; Epidemiologic Methods; Humans; Influenza, Human; Rimantadine; Russia; Time Factors; Urban Population	1983
[Efficacy of remantadin in influenza B]. Terapevticheskii arkhiv, 1983, Volume: 55, Issue:9 Topics: Adamantane; Adult; Humans; Influenza, Human; Orthomyxoviridae; Rimantadine; Russia; Serotyping	1983
[Effectiveness of remantadine in outpatients during a period of epidemic outbreaks of influenza A and B]. Zhurnal mikrobiologii, epidemiologii i immunobiologii, 1984, Issue:1 Topics: Absenteeism; Adamantane; Ambulatory Care; Disease Outbreaks; Drug Evaluation; Humans; Influenza, Human; Rimantadine; Russia; Urban Population	1984
[New organized approach to rendering medical services to patients during influenza outbreak]. Terapevticheskii arkhiv, 1984, Volume: 56, Issue:1 Topics: Adamantane; Antiviral Agents; Disease Outbreaks; Humans; Influenza A virus; Influenza, Human; Rimantadine; Russia	1984
Interaction of influenza virus proteins with planar bilayer lipid membranes. II. Effects of rimantadine and amantadine. Biochimica et biophysica acta, 1984, Dec-05, Volume: 778, Issue:2 Topics: Adamantane; Amantadine; Dose-Response Relationship, Drug; Kinetics; Lipid Bilayers; Membrane Potentials; Phosphatidylcholines; Phospholipids; Rimantadine; Viral Matrix Proteins; Viral Proteins	1984
[Antiviral activity of remantadine evaluated by a pathomorphological study of the lungs of mice infected by influenza virus]. Medycyna doswiadczalna i mikrobiologia, 1984, Volume: 36, Issue:4 Topics: Adamantane; Animals; Influenza A virus; Lung; Mice; Mice, Inbred BALB C; Orthomyxoviridae Infections; Rimantadine	1984
[Emergency prevention of influenza with remantadine]. Meditsinskaia sestra, 1984, Volume: 43, Issue:3 Topics: Adamantane; Adolescent; Adult; Disease Outbreaks; Humans; Influenza, Human; Rimantadine; USSR	1984
[Amantadine and riamantadine in the treatment of influenza]. Recenti progressi in medicina, 1983, Volume: 74, Issue:3 Topics: Adamantane; Amantadine; Humans; Influenza, Human; Rimantadine	1983
Dansylcadaverine and rimantadine inhibition of phagocytosis, PAF-acether release, and phosphatidylcholine synthesis in human polymorphonuclear leukocytes. Immunopharmacology, 1983, Volume: 6, Issue:4 Topics: Adamantane; Amantadine; Antineoplastic Agents; Cadaverine; Diamines; Humans; Neutrophils; Phagocytosis; Phosphatidylcholines; Platelet Activating Factor; Rimantadine	1983
Treatment of intracranial dengue virus infections in mice with a lipophilic derivative of ribavirin. Antimicrobial agents and chemotherapy, 1983, Volume: 24, Issue:1 Topics: Adamantane; Animals; Brain Diseases; Dengue; Female; Mercaptopurine; Mice; Mice, Inbred BALB C; Ribavirin; Ribonucleosides; Rimantadine	1983
Combined interferon-alpha 2, rimantadine hydrochloride, and ribavirin inhibition of influenza virus replication in vitro. Antimicrobial agents and chemotherapy, 1984, Volume: 25, Issue:1 Topics: Adamantane; Animals; Drug Combinations; Drug Interactions; Influenza A virus; Interferon Type I; Kidney; Macaca mulatta; Orthomyxoviridae; Ribavirin; Ribonucleosides; Rimantadine; Virus Replication	1984
Influence of membrane (M) protein on influenza A virus virion transcriptase activity in vitro and its susceptibility to rimantadine. Journal of virology, 1980, Volume: 33, Issue:2 Topics: Adamantane; Animals; Chick Embryo; Drug Resistance, Microbial; Influenza A virus; Membrane Proteins; Rimantadine; RNA Nucleotidyltransferases; RNA-Dependent RNA Polymerase; RNA, Viral	1980
Influenza virus uncoating in infected cells and effect of rimantadine. The Journal of general virology, 1982, Volume: 60, Issue:Pt 1 Topics: Adamantane; Animals; Cell Line; Cell Nucleus; Chick Embryo; Dogs; Influenza A virus; Ribonucleoproteins; Rimantadine; Viral Matrix Proteins; Viral Proteins; Virus Replication	1982
Uncoating of a rimantadine-resistant variant of influenza virus in the presence of rimantadine. The Journal of general virology, 1982, Volume: 60, Issue:Pt 1 Topics: Adamantane; Animals; Cell Line; Cell Nucleus; Dogs; Drug Resistance, Microbial; Influenza A virus; Ribonucleoproteins; Rimantadine; Viral Matrix Proteins; Viral Proteins; Virus Replication	1982
Anti-influenza A virus activity of amantadine hydrochloride and rimantadine hydrochloride in ferret tracheal ciliated epithelium. Antimicrobial agents and chemotherapy, 1982, Volume: 21, Issue:5 Topics: Adamantane; Amantadine; Animals; Cilia; Cytopathogenic Effect, Viral; Epithelium; Ferrets; In Vitro Techniques; Influenza A virus; Rimantadine; Time Factors; Trachea; Virus Cultivation	1982
[Results of tests for carcinogenic, teratogenic and embryotoxic action of remantadin]. Voprosy onkologii, 1982, Volume: 28, Issue:9 Topics: Abnormalities, Drug-Induced; Adamantane; Animals; Embryo, Mammalian; Female; Male; Mice; Neoplasms, Experimental; Orthomyxoviridae Infections; Rats; Rimantadine	1982
[Emergency prevention of influenza with remantadin]. Zhurnal mikrobiologii, epidemiologii i immunobiologii, 1982, Issue:9 Topics: Adamantane; Adolescent; Adult; Disease Outbreaks; Drug Evaluation; Female; Humans; Influenza Vaccines; Influenza, Human; Male; Placebos; Rimantadine; USSR	1982
[Inhibitory effect of rimantidine hydrochloride (alpha-methyl-1-adamantan methylamine) on the synthesis of influenza virus proteins]. Doklady Akademii nauk SSSR, 1980, Volume: 251, Issue:2 Topics: Adamantane; Animals; Chick Embryo; Fibroblasts; Influenza A virus; Rimantadine; RNA, Messenger; Viral Proteins	1980
Suppression of dengue virus replication in vitro by rimantadine hydrochloride. The American journal of tropical medicine and hygiene, 1981, Volume: 30, Issue:1 Topics: Adamantane; Animals; Dengue; Dengue Virus; Humans; Leukocytes; Macaca mulatta; Rimantadine; Time Factors; Virus Replication	1981
[Therapeutic effectiveness of rimantadine and antigrippen against A1(H1N1) influenza in the 1977-1978 epidemic]. Vrachebnoe delo, 1981, Issue:6 Topics: Adamantane; Adult; Ascorbic Acid; Aspirin; Diphenhydramine; Drug Combinations; Evaluation Studies as Topic; Humans; Influenza, Human; Lactates; Rimantadine; Rutin; USSR	1981
Toxicity of amantadine and rimantadine for the ciliated epithelium of ferret tracheal rings. The Journal of infectious diseases, 1981, Volume: 144, Issue:1 Topics: Adamantane; Amantadine; Animals; Cilia; Ferrets; In Vitro Techniques; Rimantadine; Trachea	1981
[Experience with clinical trials of the new anti-influenza drug rimantadine]. Vrachebnoe delo, 1981, Issue:4 Topics: Adamantane; Antiviral Agents; Ascorbic Acid; Aspirin; Diphenhydramine; Drug Combinations; Humans; Influenza, Human; Lactates; Retrospective Studies; Rimantadine; Rutin	1981
[Clinical use of the anti-influenza preparation rimantadine]. Klinicheskaia meditsina, 1981, Volume: 59, Issue:2 Topics: Adamantane; Humans; Influenza A virus; Influenza, Human; Rimantadine	1981
Comparison of amantadine and rimantadine for prevention of type A (Russian) influenza. Antiviral research, 1981, Volume: 1, Issue:3 Topics: Adamantane; Adolescent; Adult; Age Factors; Amantadine; Antibodies, Viral; Double-Blind Method; Drug Evaluation; Female; Humans; Influenza A virus; Influenza, Human; Male; Rimantadine	1981
Rimantadine hydrochloride blocks the second step of influenza virus uncoating. Archives of virology, 1980, Volume: 66, Issue:3 Topics: Adamantane; Adsorption; Animals; Cell Line; Cell Nucleus; Cytoplasm; Dogs; Influenza A virus; Ribonucleoproteins; Rimantadine; Viral Proteins	1980
[Comparative study of the mechanism of inhibition of Sindbis virus reproduction by adamantane derivatives: remantadine and amide of 1-adamantane carboxylic acid]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1996, Volume: 41, Issue:7-8 Topics: Adamantane; Adsorption; Animals; Antiviral Agents; Chlorocebus aethiops; Nucleic Acid Synthesis Inhibitors; Rimantadine; RNA, Viral; Sindbis Virus; Vero Cells; Viral Proteins; Virus Replication	1996
[Effect of the amide of 1-adamantanecarboxylic acid (AACA) and its combination with ribavirin on the course of experimental infection, caused by the sindbis virus in tissue culture and in mouse brain. Possible isolation of the virus mutant resistant to ri Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1997, Volume: 42, Issue:7 Topics: Adamantane; Alphavirus Infections; Animals; Antiviral Agents; Brain Diseases; Chlorocebus aethiops; Drug Resistance, Microbial; Drug Therapy, Combination; Mice; Mutation; Ribavirin; Rimantadine; Sindbis Virus; Vero Cells	1997
[Treatment of influenza in children]. Zhonghua er ke za zhi = Chinese journal of pediatrics, 2003, Volume: 41, Issue:2 Topics: Adamantane; Amantadine; Antiviral Agents; Child; Guanidines; Humans; Influenza, Human; Pyrans; Rimantadine; Sialic Acids; Zanamivir	2003
Increased adamantane resistance in influenza A(H3) viruses in Australia and neighbouring countries in 2005. Antiviral research, 2007, Volume: 73, Issue:2 Topics: Adamantane; Antiviral Agents; Australia; Drug Resistance, Viral; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Influenza A virus; Influenza, Human; Mutation; Neuraminidase; Oseltamivir; Phylogeny; Rimantadine; Zanamivir	2007
The emergence of adamantane resistance in influenza A(H1) viruses in Australia and regionally in 2006. Antiviral research, 2007, Volume: 75, Issue:2 Topics: Adamantane; Adolescent; Adult; Aged; Amino Acid Substitution; Antiviral Agents; Asia, Eastern; Asia, Southeastern; Australia; Child; Child, Preschool; Drug Resistance, Viral; Genotype; Humans; Infant; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza, Human; Middle Aged; Pacific Islands; Prevalence; Rimantadine; South Africa	2007
Design, synthesis, and trypanocidal activity of new aminoadamantane derivatives. Journal of medicinal chemistry, 2008, Mar-13, Volume: 51, Issue:5 Topics: Adamantane; Amantadine; Animals; Parasitic Sensitivity Tests; Rimantadine; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei	2008
Design and synthesis of 1,2-annulated adamantane piperidines with anti-influenza virus activity. Bioorganic & medicinal chemistry, 2009, Feb-15, Volume: 17, Issue:4 Topics: Adamantane; Animals; Antiviral Agents; Dogs; Humans; Influenza A Virus, H3N2 Subtype; Magnetic Resonance Spectroscopy; Molecular Structure; Piperidines; Rimantadine; Structure-Activity Relationship	2009
Insights from investigating the interactions of adamantane-based drugs with the M2 proton channel from the H1N1 swine virus. Biochemical and biophysical research communications, 2009, Oct-16, Volume: 388, Issue:2 Topics: Adamantane; Amino Acid Sequence; Animals; Antiviral Agents; Drug Design; Humans; Influenza A Virus, H1N1 Subtype; Male; Middle Aged; Molecular Sequence Data; Protein Binding; Protein Conformation; Rimantadine; Viral Matrix Proteins	2009
Safety of oseltamivir compared with the adamantanes in children less than 12 months of age. The Pediatric infectious disease journal, 2010, Volume: 29, Issue:3 Topics: Adamantane; Antiviral Agents; Central Nervous System; Female; Humans; Infant; Infant, Newborn; Influenza, Human; Male; Nervous System Diseases; Oseltamivir; Retrospective Studies; Rimantadine	2010
Designing inhibitors of M2 proton channel against H1N1 swine influenza virus. PloS one, 2010, Feb-23, Volume: 5, Issue:2 Topics: Adamantane; Amino Acid Sequence; Animals; Antiviral Agents; Binding Sites; Drug Design; Drug Resistance, Viral; Influenza A Virus, H1N1 Subtype; Ion Channels; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutation; Orthomyxoviridae Infections; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Rimantadine; Sequence Homology, Amino Acid; Swine; Swine Diseases; Viral Matrix Proteins	2010
Influenza antiviral prescribing practices during the 2007-08 and 2008-09 influenza seasons in the setting of increased resistance to oseltamivir among circulating influenza viruses. Antiviral research, 2010, Volume: 88, Issue:2 Topics: Adamantane; Antiviral Agents; Disease Outbreaks; Drug Resistance, Viral; Drug Utilization; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza, Human; Oseltamivir; Practice Guidelines as Topic; Practice Patterns, Physicians'; Retrospective Studies; Rimantadine; Seasons; Surveys and Questionnaires; Zanamivir	2010
A comprehensive surveillance of adamantane resistance among human influenza A virus isolated from mainland China between 1956 and 2009. Antiviral therapy, 2010, Volume: 15, Issue:6 Topics: Adamantane; Antiviral Agents; China; Drug Resistance, Viral; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza A Virus, H5N1 Subtype; Phylogeny; Rimantadine; RNA, Viral; Sentinel Surveillance; Sequence Analysis, Protein; Sequence Analysis, RNA; Viral Matrix Proteins	2010
How do aminoadamantanes block the influenza M2 channel, and how does resistance develop? Journal of the American Chemical Society, 2011, Jun-29, Volume: 133, Issue:25 Topics: Adamantane; Amantadine; Antiviral Agents; Binding Sites; Drug Resistance, Viral; Humans; Ion Channels; Mutation; Rimantadine; Static Electricity; Viral Matrix Proteins	2011
[Influenza : clinical symptoms, diagnostics and therapy]. Der Internist, 2011, Volume: 52, Issue:9 Topics: Adamantane; Adult; Age Factors; Aged; AIDS-Related Opportunistic Infections; Antiviral Agents; Child; Child, Preschool; Female; Germany; Humans; Infant; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Neuraminidase; Pandemics; Pneumonia, Viral; Population Surveillance; Pregnancy; Rimantadine; Survival Rate	2011
New adamantane derivatives can overcome resistance of influenza A(H1N1)pdm2009 and A(H3N2) viruses to remantadine. Bulletin of experimental biology and medicine, 2012, Volume: 153, Issue:2 Topics: Adamantane; Antiviral Agents; Drug Resistance, Viral; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Rimantadine	2012
Unusual architecture of the p7 channel from hepatitis C virus. Nature, 2013, Jun-27, Volume: 498, Issue:7455 Topics: Adamantane; Binding Sites; Diffusion; Hepacivirus; Microscopy, Electron; Models, Biological; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Porosity; Rimantadine; Structure-Activity Relationship; Viral Proteins	2013
Aminoadamantanes with persistent in vitro efficacy against H1N1 (2009) influenza A. Journal of medicinal chemistry, 2014, Jun-12, Volume: 57, Issue:11 Topics: Adamantane; Amantadine; Animals; Antiviral Agents; Dogs; Drug Resistance, Multiple, Viral; HEK293 Cells; Humans; Influenza A Virus, H1N1 Subtype; Ion Channels; Madin Darby Canine Kidney Cells; Mutation; Rimantadine; Viral Matrix Proteins	2014
Amino acid derivatives of adamantane carbocycle are capable of inhibiting replication of highly virulent avian influenza A/H5N1 virus. Bulletin of experimental biology and medicine, 2014, Volume: 157, Issue:1 Topics: Adamantane; Animals; Antiviral Agents; Cell Line; Embryo, Mammalian; Epithelial Cells; Histidine; Humans; Influenza A Virus, H5N1 Subtype; Kidney; Rimantadine; Serine; Swine; Virulence; Virus Replication	2014
Stereoselective synthesis of novel adamantane derivatives with high potency against rimantadine-resistant influenza A virus strains. Organic & biomolecular chemistry, 2017, Apr-11, Volume: 15, Issue:15 Topics: Adamantane; Antiviral Agents; Chemistry Techniques, Synthetic; Drug Resistance, Viral; Influenza A Virus, H1N1 Subtype; Rimantadine; Stereoisomerism	2017
Symmetric dimeric adamantanes for exploring the structure of two viroporins: influenza virus M2 and hepatitis C virus p7. Drug design, development and therapy, 2018, Volume: 12 Topics: Adamantane; Amantadine; Antiviral Agents; Cells, Cultured; Drug Design; HEK293 Cells; Humans; Models, Molecular; Molecular Structure; Rimantadine; Viral Matrix Proteins; Viral Proteins	2018
Synthetic Analogues of Aminoadamantane as Influenza Viral Inhibitors-In Vitro, In Silico and QSAR Studies. Molecules (Basel, Switzerland), 2020, Sep-01, Volume: 25, Issue:17 Topics: Adamantane; Animals; Antiviral Agents; Binding Sites; Cell Death; Computer Simulation; Crystallography, X-Ray; Differential Thermal Analysis; Dogs; Drug Stability; Humans; Hydrogen Bonding; Least-Squares Analysis; Madin Darby Canine Kidney Cells; Molecular Conformation; Molecular Docking Simulation; Orthomyxoviridae; Protein Domains; Quantitative Structure-Activity Relationship; Rimantadine; Temperature; Viral Matrix Proteins	2020
Metabolic profiling to evaluate the impact of amantadine and rimantadine on the secondary metabolism of a model organism. Scientific reports, 2023, 10-05, Volume: 13, Issue:1 Topics: Adamantane; Amantadine; Metabolic Clearance Rate; Rimantadine; Secondary Metabolism	2023