Page last updated: 2024-08-21

adamantane and platensimycin

adamantane has been researched along with platensimycin in 106 studies

Research

Studies (106)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	45 (42.45)	29.6817
2010's	55 (51.89)	24.3611
2020's	6 (5.66)	2.80

Authors

Authors	Studies
Pearson, H	1
Brown, ED	1
Allocco, J; Barrett, J; Bartizal, K; Basilio, A; Becker, JW; Colwell, L; Cully, D; Cummings, R; Dorso, K; Felcetto, T; Galgoci, A; Genilloud, O; Gill, C; Ha, S; Herath, K; Hermes, JD; Hernandez, L; Jayasuriya, H; Kodali, S; Lee, SH; Michael, B; Motyl, M; Ondeyka, J; Painter, R; Parthasarathy, G; Pelaez, F; Schmatz, D; Shoop, W; Silver, LL; Singh, SB; Soisson, SM; Tang, YS; Tormo, JR; Vicente, F; Wang, J; Young, K; Zhang, C	1
Häbich, D; von Nussbaum, F	1
Ball, RG; Basilio, A; Diez, MT; Genilloud, O; Herath, KB; Jayasuriya, H; Ondeyka, JG; Pelaez, F; Singh, SB; Tsou, NN; Vicente, F; Wang, J; Young, K; Zhang, C; Zink, DL	1
Dingermann, T; Holzgrabe, U; Zündorf, I	1
Edmonds, DJ; Li, A; Nicolaou, KC	1
Williams, D	1
Chen, CH; Foxman, BM; Snider, BB; Taylor, CD; Zou, Y	1
Edmonds, DJ; Li, A; Nicolaou, KC; Tria, GS	1
Kaliappan, KP; Ravikumar, V	1
Denton, RM; Edmonds, DJ; Lister, T; Montero, A; Nicolaou, KC	1
Micklefield, J; Wilkinson, B	1
Li, P; Payette, JN; Yamamoto, H	1
Nicolaou, KC; Tang, Y; Wang, J	1
Ghosh, AK; Xi, K	2
Mulzer, J; Tiefenbacher, K	2
Corey, EJ; Lalic, G	1
Li, A; Montero, A; Nicolaou, KC; Stepan, AF; Tang, Y; Wang, J	1
Attygalle, AB; Herath, KB; Singh, SB	1
Chen, DY; Gibe, R; Nicolaou, KC; Pappo, D; Tsang, KY	1
Capuano, B; Crosby, IT; Khakham, Y; Manallack, DT	1
Burgess, B; Herath, KB; Jayasuriya, H; Ondeyka, JG; Singh, SB; Wang, J; Zhang, C; Zink, DL	1
Choi, SY; Chung, YK; Jang, KP; Kim, CH; Lee, E	1
Bracher, F; Knorr, V; Krauss, J; Manhardt, V; Scheffels, S	1
Corey, EJ; Yeung, YY	1
Rutjes, FP; Schaapman, MC; van Delft, FL; Waalboer, DC	1
Ishibashi, H; Matsuo, J; Takeuchi, K	1
Grininger, M; Johansson, P; Kessler, B; Kumari, P; Oesterhelt, D; Vonck, J; Vonrhein, C; Wiltschi, B	1
Denton, RM; Edmonds, DJ; Li, A; Lister, T; Montero, A; Nicolaou, KC; Stepan, AF; Tang, Y; Tria, GS; Turner, CI; Wang, J	1
Burgess, B; Ondeyka, J; Singh, SB; Wang, J; Zhang, C; Zink, DL	1
Peterson, RM; Rajski, SR; Shen, B; Smanski, MJ	1
Lee, V; Sintim, HO; Wang, J	1
Chen, X; Colletti, SL; Ding, FX; Dorso, K; Ha, SN; Hammond, ML; Kodali, S; Maccoss, M; Parthasarathy, G; Shen, HC; Singh, SB; Soisson, SM; Tata, JR; Wang, J	1
Lee, D; Yun, SY; Zheng, JC	1
Becker, JW; Herath, KB; Jayasuriya, H; Ondeyka, JG; Parthasarathy, G; Singh, SB; Soisson, SM; Wang, J; Zhang, C; Zink, DL	1
Jang, KP; Kang, H; Kim, CH; Kim, H; Lee, E; Na, SW	1
Edmonds, DJ; Ellery, SP; Li, A; Nicolaou, KC	1
Besra, GS; Bhatt, A; Brown, AK; Fütterer, K; Taylor, RC	1
Bandow, JE; Gasser, G; Merz, K; Metzler-Nolte, N; Ott, I; Patra, M; Pinto, A	1
Bartlett, ES; McGrath, NA; Njardarson, JT; Sittihan, S	1
Edmonds, DJ; Ellery, SP; Li, A; Nicolaou, KC; Tria, GS	1
Burgess, B; Dietrich, L; Guan, Z; Ondeyka, J; Singh, SB; Wang, J; Zhang, C	1
Chen, Y; Shen, B; Smanski, MJ	1
Lu, X; You, Q	1
Jang, DS; Jang, KP; Kang, H; Kim, CH; Kim, H; Lee, E; Na, SW	1
Kaliappan, KP; Palanichamy, K	1
Achache, N; Beaulieu, MA; Canesi, S; Guérard, KC; Sabot, C	1
Genilloud, O; González, I; Martín, J; Salazar, O; Tormo, JR; Vicente, F	1
Eey, ST; Lear, MJ	1
Lynch, V; Magnus, P; Rivera, H	1
Burgess, B; Dietrich, L; Guan, Z; Ha, SN; Herath, K; Jayasuriya, H; Ondeyka, J; Singh, SB; Wang, J; Zhang, C; Zink, DL	1
Sintim, HO; Wang, J	1
Albrecht, D; Bandow, JE; Chen, DY; Metzler-Nolte, N; Nicolaou, KC; Patra, M; Wenzel, M	1
Chung, CC; Ellsworth, KP; Karanam, BV; Lassman, ME; Lee, SH; Li, C; Miller, C; Myers, RW; Powles, M; Salituro, G; Singh, SB; Tota, MR; Wang, J; Wu, M; Zhang, BB	1
Oblak, EZ; Wright, DL	1
Ahmed, I; Hussain, H; Krohn, K; Saleem, M; van Ree, T	1
Casper, J; Chen, Y; Lin, S; Peterson, RM; Rajski, SR; Shen, B; Smanski, MJ; Wendt-Pienkowski, E; Yu, Z	1
Demain, AL; Martens, E	1
Beaulieu, MA; Canesi, S; Guérard, KC; Maertens, G; Sabot, C	1
Merz, K; Metzler-Nolte, N; Patra, M	1
Gasser, G; Metzler-Nolte, N; Patra, M	1
Bracher, F; Krauss, J; Plesch, E	1
Peterson, RM; Shen, B; Smanski, MJ	1
Casper, J; Peterson, RM; Rajski, SR; Shen, B; Smanski, MJ; Yu, Z	1
Aluotto, S; Demain, AL; Falzone, M; Gullo, V; Maggio, C; Mukherjee, A; Tynan, H	1
Du, G; Han, Y; Lee, CS; Zhu, L	1
Horii, S; Kuwahara, S; Nagasawa, T; Torihata, M	1
Cheng, GJ; He, S; Lee, CS; Yang, W; Zhang, X; Zhou, C; Zhu, L	1
Chiappini, N; Crespo, E; Demain, AL; Falzone, M; Friedman, E; Gelber, M; Golden, S; Gullo, V; Inamine, G; Lemence, R; Maggio, C; Martens, E; Nayda, V; Shen, B; Tynan, H	1
Oblak, EZ; VanHeyst, MD; Wright, DL	1
Basak, R; Fisher, M; Fishwick, CW; Kalverda, AP; Nelson, A; Turnbull, WB	1
Huang, T; Peterson, RM; Rudolf, JD; Shen, B; Smanski, MJ	1
Duan, Y; Huang, T; Huang, Y; Jiang, Y; Lohman, JR; Rudolf, JD; Shen, B; Teng, Q; Xie, G; Xie, P; Yang, D; Zhao, LX; Zhu, X	1
Alvarenga, ES; Amorim, KB; Demuner, AJ; Moraes, FC; Pereira-Flores, ME	1
Dong, LB; Huang, T; Rudolf, JD; Shen, B	1
Cember, A; Guo, M; Rowe, I; Sintim, HO; Sukharev, S; Yasmann, A	1
Baum, B; Brenk, R; Hunter, WN; Jaenicke, E; Lecker, LS; Schnell, R; Zoltner, M	1
Liang, J; Liu, Y; Shang, R; Wang, J; Yi, Y	1
Duan, Y; Huang, Y; Liu, L; Lu, S; Pan, J; Shen, B; Shi, J; Yang, D; Zhu, X	1
Dong, LB; Rudolf, JD; Shen, B	3
Dong, LB; Manoogian, K; Rudolf, JD; Shen, B	1
Cameron, MD; Dong, LB; Lin, L; Rudolf, JD; Ruiz, C; Shen, B	1
Crespo, E; Demain, AL; Falzone, M; Gelber, M; Gullo, V; Jones, K; Khan, G; Komal, R; Korn, VL; Nayda, V; Patel, A; Patel, K; Patel, M; Perkins, C; Ravin, A; Rudolf, JD; Scheffler, R; Shen, B; Siddiqui, S; Stenger, D; Yu, E	1
Andersson, CD; Bastidas, RJ; Elofsson, M; Engström, P; Gylfe, Å; Hedenström, M; Mojica, SA; Núñez-Otero, C; Salin, O; Sunduru, N; Valdivia, RH	1
Deng, Y; Duan, Y; Huang, Y; Kang, D; Liang, H; Qiu, L; Shen, B; Tian, K; Wen, Z; Zhu, X	1
Deng, Y; Dong, LB; Duan, Y; He, CQ; Houk, KN; Huang, Y; Kang, D; Rudolf, JD; Shen, B; Wang, N	1
Dong, LB; Renata, H; Rudolf, JD; Shen, B; Zhang, X	1
Adhikari, A; Shen, B; Teijaro, CN	1
Deng, Y; Duan, Y; Huang, Y; Kang, D; Li, Y; Liu, X; Qiu, L; Shen, B; Su, M; Wen, Z	1
Casarrubios, L; de la Torre, MC; Sierra, MA	1
Cepeda, AJ; Deng, MR; Dong, LB; Kalkreuter, E; Renata, H; Rudolf, JD; Shen, B; Zhang, X	1
Cameron, MD; Deng, Y; Dong, LB; Duan, Y; Feng, X; Huang, Y; Qiu, L; Rudolf, JD; Ruiz, CH; Shen, B; Su, M	1
Deng, Y; Duan, Y; Huang, Y; Ji, X; Li, Y; Ren, N; Shen, B; Su, M; Wen, Z; Weng, X	1
Cepeda, AJ; Chang, C; Deng, MR; Dong, LB; Joachimiak, A; Kalkreuter, E; Liu, YC; Phillips, GN; Rudolf, JD; Shen, B	1
Shen, B; Steele, AD; Teijaro, CN; Yang, D	1
Bai, E; Duan, Y; Feng, X; Huang, Y; Liu, X; Shen, B; Wang, Z; Xiong, Y; Zhu, X	1
Attygalle, AB; Genilloud, O; González, I; Herath, KB; Previs, SF; Roddy, TP; Singh, SB	1
Duan, Y; Huang, Y; Liu, X; Wang, Z	1
Bai, E; Duan, Y; Huang, Y; Kong, J; Ren, N; Tan, Q; Xiong, Y; Yi, S; Zhu, X	1
Bai, E; Chen, X; Duan, Y; Huang, Y; Li, D; Wang, Z; Zhang, H	1
Amaro, JM; Barrero, AF; Galisteo, A; Pérez, Á; Quílez Del Moral, JF	1

Reviews

16 review(s) available for adamantane and platensimycin

Article	Year
Platensimycin, a new antibiotic and "superbug challenger" from nature. ChemMedChem, 2006, Volume: 1, Issue:9 Topics: Adamantane; Aminobenzoates; Anilides; Anti-Bacterial Agents; Bacteria; Drug Resistance, Bacterial; Fatty Acids; RNA Interference; Structure-Activity Relationship	2006
Mining and engineering natural-product biosynthetic pathways. Nature chemical biology, 2007, Volume: 3, Issue:7 Topics: Adamantane; Aminobenzoates; Anilides; Antimalarials; Artemisinins; Biological Factors; Combinatorial Chemistry Techniques; Genetic Engineering; Molecular Structure; Yeasts	2007
Synthesis of platensimycin. Angewandte Chemie (International ed. in English), 2008, Volume: 47, Issue:14 Topics: Adamantane; Aminobenzoates; Anilides; Stereoisomerism	2008
Platensimycin: a promising antimicrobial targeting fatty acid synthesis. Current medicinal chemistry, 2008, Volume: 15, Issue:7 Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Adamantane; Aminobenzoates; Aminophenols; Anilides; Animals; Anti-Infective Agents; Fatty Acids; Humans; Molecular Structure; Polycyclic Compounds; Structure-Activity Relationship	2008
Improvement of secondary metabolite production in Streptomyces by manipulating pathway regulation. Applied microbiology and biotechnology, 2010, Volume: 86, Issue:1 Topics: Adamantane; Aminobenzoates; Aminoglycosides; Aminophenols; Anilides; Anti-Infective Agents; Bacterial Proteins; Biotechnology; Enediynes; Fermentation; Gene Expression Regulation, Bacterial; Genetic Engineering; Polycyclic Compounds; Streptomyces	2010
Recent advances on platensimycin: a potential antimicrobial agent. Current medicinal chemistry, 2010, Volume: 17, Issue:12 Topics: Adamantane; Aminobenzoates; Anilides; Anti-Bacterial Agents; Humans; Microbial Sensitivity Tests; Structure-Activity Relationship	2010
Discovery and syntheses of "superbug challengers"-platensimycin and platencin. Chemistry, an Asian journal, 2010, Apr-01, Volume: 5, Issue:4 Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Anti-Infective Agents; Drug Discovery; Drug Resistance, Multiple, Bacterial; Fatty Acid Synthesis Inhibitors; Polycyclic Compounds	2010
Current approaches to exploit actinomycetes as a source of novel natural products. Journal of industrial microbiology & biotechnology, 2011, Volume: 38, Issue:3 Topics: Actinobacteria; Adamantane; Aminobenzoates; Anilides; Anti-Bacterial Agents; Biodiversity; Biological Products; Drug Discovery; Drug Industry; Fermentation; High-Throughput Screening Assays; Spain	2011
Platensimycin and its relatives: a recent story in the struggle to develop new naturally derived antibiotics. Natural product reports, 2011, Volume: 28, Issue:9 Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Anti-Bacterial Agents; Biological Products; Drug Design; Drug Resistance, Multiple; Enterococcus faecalis; Methicillin-Resistant Staphylococcus aureus; Polycyclic Compounds; Streptococcus pneumoniae; Structure-Activity Relationship	2011
Platensimycin and platencin: promising antibiotics for future application in human medicine. The Journal of antibiotics, 2011, Volume: 64, Issue:11 Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Anti-Bacterial Agents; Fatty Acids; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Lipid Metabolism; Models, Molecular; Molecular Structure; Polycyclic Compounds; Streptomyces	2011
Small organometallic compounds as antibacterial agents. Dalton transactions (Cambridge, England : 2003), 2012, Jun-07, Volume: 41, Issue:21 Topics: Adamantane; Aminobenzoates; Anilides; Anti-Bacterial Agents; Methane; Organometallic Compounds; Penicillins; Quinolones	2012
Review of Platensimycin and Platencin: Inhibitors of β-Ketoacyl-acyl Carrier Protein (ACP) Synthase III (FabH). Molecules (Basel, Switzerland), 2015, Sep-03, Volume: 20, Issue:9 Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Anti-Bacterial Agents; Bacterial Proteins; Drug Resistance, Bacterial; Fatty Acid Synthase, Type II; Molecular Structure; Polycyclic Compounds; Streptomyces	2015
Platensimycin and platencin: Inspirations for chemistry, biology, enzymology, and medicine. Biochemical pharmacology, 2017, 06-01, Volume: 133 Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Animals; Anti-Infective Agents; Communicable Diseases; Humans; Polycyclic Compounds; Protein Structure, Secondary; Protein Structure, Tertiary; Structure-Activity Relationship	2017
Challenges and opportunities for natural product discovery, production, and engineering in native producers versus heterologous hosts. Journal of industrial microbiology & biotechnology, 2019, Volume: 46, Issue:3-4 Topics: Adamantane; Aminobenzoates; Aminoglycosides; Aminophenols; Anilides; Bacterial Proteins; Biological Products; Biosynthetic Pathways; Drug Discovery; Enediynes; Gene Expression Regulation, Bacterial; Genes, Bacterial; Lactams; Macrolides; Metabolic Engineering; Multigene Family; Piperidones; Polycyclic Compounds; Protein Conformation; Sequence Analysis, DNA; Streptomyces; Thiazoles; Thiones	2019
Bio-Organometallic Derivatives of Antibacterial Drugs. Chemistry (Weinheim an der Bergstrasse, Germany), 2019, May-28, Volume: 25, Issue:30 Topics: Adamantane; Aminobenzoates; Anilides; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Biocompatible Materials; Biomimetic Materials; Humans; Metals; Molecular Structure; Organometallic Compounds; Structure-Activity Relationship	2019
Leveraging a large microbial strain collection for natural product discovery. The Journal of biological chemistry, 2019, 11-08, Volume: 294, Issue:45 Topics: Adamantane; Aminobenzoates; Anilides; Bacteria; Biological Products; Computational Biology; Databases, Genetic; Fungi; Genome, Bacterial; Multigene Family	2019

Other Studies

90 other study(ies) available for adamantane and platensimycin

Article	Year
Antibiotic faces uncertain future. Nature, 2006, May-18, Volume: 441, Issue:7091 Topics: Adamantane; Aminobenzoates; Aminoglycosides; Anilides; Animals; Anti-Bacterial Agents; Bacteria; Cell Wall; Clinical Trials as Topic; Drug Evaluation, Preclinical; Drug Industry; Fatty Acids; Humans; Mice	2006
Microbiology: antibiotic stops 'ping-pong' match. Nature, 2006, May-18, Volume: 441, Issue:7091 Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Adamantane; Aminobenzoates; Aminoglycosides; Anilides; Animals; Anti-Bacterial Agents; Bacteria; Binding Sites; Catalysis; Drug Resistance, Bacterial; Fatty Acids; Humans; Mice	2006
Platensimycin is a selective FabF inhibitor with potent antibiotic properties. Nature, 2006, May-18, Volume: 441, Issue:7091 Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Acetamides; Adamantane; Aminobenzoates; Aminoglycosides; Anilides; Animals; Anti-Bacterial Agents; Apoproteins; Bacterial Proteins; Crystallography, X-Ray; Linezolid; Lipids; Mice; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Oxazolidinones; Streptomyces; Substrate Specificity	2006
Isolation, structure, and absolute stereochemistry of platensimycin, a broad spectrum antibiotic discovered using an antisense differential sensitivity strategy. Journal of the American Chemical Society, 2006, Sep-13, Volume: 128, Issue:36 Topics: Adamantane; Aminobenzoates; Anilides; Anti-Bacterial Agents; Crystallography, X-Ray; Models, Molecular; Molecular Conformation; Nuclear Magnetic Resonance, Biomolecular; Stereoisomerism; Streptomyces	2006
[An old pathway to new antibiotics--platensimycin]. Pharmazie in unserer Zeit, 2006, Volume: 35, Issue:5 Topics: Adamantane; Aminobenzoates; Anilides; Anti-Bacterial Agents; Streptomyces	2006
Total synthesis of platensimycin. Angewandte Chemie (International ed. in English), 2006, Oct-27, Volume: 45, Issue:42 Topics: Adamantane; Aminobenzoates; Anilides; Anti-Bacterial Agents; Indicators and Reagents; Iodides; Magnetic Resonance Spectroscopy; Samarium; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Structure-Activity Relationship	2006
Material surfaces and MRSA. Medical device technology, 2006, Volume: 17, Issue:7 Topics: Adamantane; Aminobenzoates; Anilides; Anti-Bacterial Agents; Chlorhexidine; Cross Infection; Equipment and Supplies, Hospital; Equipment Contamination; Infection Control; Intensive Care Units; Methicillin Resistance; Silver; Staphylococcal Infections; Staphylococcus aureus	2006
Formal synthesis of (+/-)-platensimycin. Organic letters, 2007, Apr-26, Volume: 9, Issue:9 Topics: Adamantane; Aminobenzoates; Anilides; Crystallography, X-Ray; Cyclization; Molecular Structure; Oxidation-Reduction; Water	2007
Asymmetric total syntheses of platensimycin. Angewandte Chemie (International ed. in English), 2007, Volume: 46, Issue:21 Topics: Adamantane; Aminobenzoates; Anilides; Molecular Structure; Stereoisomerism	2007
An expedient enantioselective strategy for the oxatetracyclic core of platensimycin. Organic letters, 2007, Jun-07, Volume: 9, Issue:12 Topics: Adamantane; Aminobenzoates; Anilides; Cyclization; Molecular Conformation; Stereoisomerism	2007
Adamantaplatensimycin: a bioactive analogue of platensimycin. Angewandte Chemie (International ed. in English), 2007, Volume: 46, Issue:25 Topics: Adamantane; Aminobenzoates; Anilides; Anti-Infective Agents; Models, Chemical; Molecular Structure	2007
Enantioselective route to platensimycin: an intramolecular Robinson annulation approach. Journal of the American Chemical Society, 2007, Aug-08, Volume: 129, Issue:31 Topics: Adamantane; Aminobenzoates; Anilides; Cyclization; Stereoisomerism	2007
Formal synthesis of (+/-)-platensimycin. Chemical communications (Cambridge, England), 2007, May-21, Issue:19 Topics: Adamantane; Aminobenzoates; Anilides; Anti-Bacterial Agents; Cyclization; Molecular Structure	2007
Enantioselective synthesis of (-)-platensimycin oxatetracyclic core by using an intramolecular Diels-Alder reaction. Organic letters, 2007, Sep-27, Volume: 9, Issue:20 Topics: Adamantane; Aminobenzoates; Anilides; Cyclization; Ketones; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Stereoisomerism	2007
Protecting-group-free formal synthesis of platensimycin. Angewandte Chemie (International ed. in English), 2007, Volume: 46, Issue:42 Topics: Adamantane; Aminobenzoates; Anilides; Molecular Structure; Stereoisomerism; Streptomyces	2007
An effective enantioselective route to the platensimycin core. Organic letters, 2007, Nov-08, Volume: 9, Issue:23 Topics: Adamantane; Aminobenzoates; Anilides; Magnetic Resonance Spectroscopy; Molecular Structure; Stereoisomerism	2007
Total synthesis and antibacterial properties of carbaplatensimycin. Journal of the American Chemical Society, 2007, Dec-05, Volume: 129, Issue:48 Topics: Adamantane; Aminobenzoates; Anilides; Anti-Bacterial Agents; Microbial Viability; Models, Molecular; Molecular Structure; Polycyclic Compounds	2007
Biosynthetic studies of platensimycin. Journal of the American Chemical Society, 2007, Dec-19, Volume: 129, Issue:50 Topics: Adamantane; Aminobenzoates; Anilides; Models, Molecular; Molecular Structure	2007
A chiral pool based synthesis of platensimycin. Angewandte Chemie (International ed. in English), 2008, Volume: 47, Issue:5 Topics: Adamantane; Aminobenzoates; Anilides; Cyclization; Cyclohexane Monoterpenes; Molecular Structure; Monoterpenes; Stereoisomerism	2008
Structure and semisynthesis of platensimide A, produced by Streptomyces platensis. Organic letters, 2008, May-01, Volume: 10, Issue:9 Topics: Adamantane; Aminobenzoates; Aminobutyrates; Aminophenols; Anilides; Anti-Bacterial Agents; Bacteria; Bridged-Ring Compounds; Microbial Sensitivity Tests; Molecular Structure; Polycyclic Compounds; Streptomyces	2008
A carbonyl ylide cycloaddition approach to platensimycin. Angewandte Chemie (International ed. in English), 2008, Volume: 47, Issue:21 Topics: Acetates; Acetonitriles; Adamantane; Alkenes; Aminobenzoates; Anilides; Catalysis; Cyclization; Molecular Structure; Rhodium; Stereoisomerism	2008
Synthesis of platensimycin analogues and their antibiotic potency. Archiv der Pharmazie, 2008, Volume: 341, Issue:6 Topics: Adamantane; Aminobenzoates; Anilides; Anti-Bacterial Agents; Antifungal Agents; Colony Count, Microbial; Fungi; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Structure-Activity Relationship	2008
A simple, efficient, and enantiocontrolled synthesis of a near-structural mimic of platensimycin. Organic letters, 2008, Sep-04, Volume: 10, Issue:17 Topics: Adamantane; Aminobenzoates; Anilides; Anti-Infective Agents; Biomimetic Materials; Stereoisomerism	2008
High-pressure entry into platencin. Angewandte Chemie (International ed. in English), 2008, Volume: 47, Issue:35 Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Anti-Bacterial Agents; Crystallography, X-Ray; Molecular Structure; Polycyclic Compounds; Pressure; Stereoisomerism	2008
Stereocontrolled formal synthesis of (+/-)-platensimycin. Organic letters, 2008, Sep-18, Volume: 10, Issue:18 Topics: Adamantane; Aminobenzoates; Anilides; Catalysis; Cyclization; Stereoisomerism	2008
Inhibition of the fungal fatty acid synthase type I multienzyme complex. Proceedings of the National Academy of Sciences of the United States of America, 2008, Sep-02, Volume: 105, Issue:35 Topics: Adamantane; Aminobenzoates; Anilides; Cerulenin; Fatty Acid Synthases; Models, Molecular; Protein Structure, Secondary; Protein Structure, Tertiary; Saccharomyces cerevisiae; Substrate Specificity; Thiophenes	2008
Design, synthesis, and biological evaluation of platensimycin analogues with varying degrees of molecular complexity. Journal of the American Chemical Society, 2008, Oct-01, Volume: 130, Issue:39 Topics: Adamantane; Aminobenzoates; Anilides; Aniline Compounds; Anti-Infective Agents; Benzaldehydes; Benzoates; Benzodioxoles; Cyclohexenes; Drug Design; Epoxy Compounds; Methicillin Resistance; Microbial Sensitivity Tests; Pyrans; Staphylococcus aureus; Structure-Activity Relationship	2008
Isolation, structure and fatty acid synthesis inhibitory activities of platensimycin B1-B3 from Streptomyces platensis. Chemical communications (Cambridge, England), 2008, Oct-28, Issue:40 Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Adamantane; Aminobenzoates; Anilides; Anti-Bacterial Agents; Fatty Acids; Staphylococcus aureus; Streptomyces	2008
Total synthesis of (-)-platensimycin, a novel antibacterial agent. The Journal of organic chemistry, 2009, Feb-06, Volume: 74, Issue:3 Topics: Adamantane; Aminobenzoates; Anilides; Anti-Infective Agents; Stereoisomerism	2009
Engineered Streptomyces platensis strains that overproduce antibiotics platensimycin and platencin. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:4 Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Anti-Bacterial Agents; Fermentation; Genetic Engineering; Hydro-Lyases; Multigene Family; Polycyclic Compounds; Polymerase Chain Reaction; Streptomyces	2009
Efforts towards the identification of simpler platensimycin analogues--the total synthesis of oxazinidinyl platensimycin. Chemistry (Weinheim an der Bergstrasse, Germany), 2009, Volume: 15, Issue:12 Topics: Adamantane; Aminobenzoates; Anilides; Anti-Bacterial Agents; Catalysis; Cyclization; Molecular Structure	2009
Synthesis and biological evaluation of platensimycin analogs. Bioorganic & medicinal chemistry letters, 2009, Mar-15, Volume: 19, Issue:6 Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Adamantane; Aminobenzoates; Anilides; Anti-Bacterial Agents; Bacterial Proteins; Chemistry, Pharmaceutical; Crystallography, X-Ray; Drug Design; Drug Resistance, Microbial; Enterococcus faecalis; Inhibitory Concentration 50; Methicillin; Microbial Sensitivity Tests; Models, Chemical; Molecular Structure; Streptomyces; Structure-Activity Relationship	2009
Stereoelectronic effect for the selectivity in C-H insertion of alkylidene carbenes and its application to the synthesis of platensimycin. Journal of the American Chemical Society, 2009, Jun-24, Volume: 131, Issue:24 Topics: Adamantane; Alkenes; Aminobenzoates; Anilides; Ethers; Ketones; Methane; Stereoisomerism	2009
Isolation, enzyme-bound structure and antibacterial activity of platencin A1 from Streptomyces platensis. Bioorganic & medicinal chemistry letters, 2009, Aug-15, Volume: 19, Issue:16 Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Anti-Bacterial Agents; Crystallography, X-Ray; Molecular Conformation; Polycyclic Compounds; Streptomyces; Structure-Activity Relationship	2009
Isoplatensimycin: Synthesis and biological evaluation. Bioorganic & medicinal chemistry letters, 2009, Aug-15, Volume: 19, Issue:16 Topics: Adamantane; Aminobenzoates; Anilides; Anti-Bacterial Agents; Enterococcus; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Vancomycin Resistance	2009
Rhodium-catalyzed asymmetric enyne cycloisomerization of terminal alkynes and formal total synthesis of (-)-platensimycin. Angewandte Chemie (International ed. in English), 2009, Volume: 48, Issue:34 Topics: Adamantane; Alkynes; Aminobenzoates; Anilides; Catalysis; Crystallography, X-Ray; Isomerism; Molecular Conformation; Rhodium	2009
Platensimycin activity against mycobacterial beta-ketoacyl-ACP synthases. PloS one, 2009, Jul-17, Volume: 4, Issue:7 Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Adamantane; Aminobenzoates; Anilides; Base Sequence; DNA Primers; Enzyme Inhibitors; Fatty Acids; Isoenzymes; Mycobacterium smegmatis; Mycobacterium tuberculosis; Mycolic Acids	2009
Synthesis and biological evaluation of chromium bioorganometallics based on the antibiotic platensimycin lead structure. ChemMedChem, 2009, Volume: 4, Issue:11 Topics: Adamantane; Aminobenzoates; Anilides; Anti-Bacterial Agents; Cell Line, Tumor; Chromium; Crystallography, X-Ray; HeLa Cells; Humans; Microbial Sensitivity Tests; Molecular Conformation; Organometallic Compounds; Spectrophotometry, Atomic	2009
A concise ring-expansion route to the compact core of platensimycin. Angewandte Chemie (International ed. in English), 2009, Volume: 48, Issue:45 Topics: Adamantane; Aminobenzoates; Anilides; Anti-Infective Agents; Models, Molecular; Molecular Structure	2009
Total synthesis of platensimycin and related natural products. Journal of the American Chemical Society, 2009, Nov-25, Volume: 131, Issue:46 Topics: Adamantane; Aldehydes; Aminobenzoates; Anilides; Anti-Bacterial Agents; Biological Products; Catalysis; Cyclization; Isomerism; Rhodium	2009
Isolation, structure and biological activities of platensimycin B4 from Streptomyces platensis. The Journal of antibiotics, 2009, Volume: 62, Issue:12 Topics: Adamantane; Aminobenzoates; Anilides; Bacterial Proteins; Enzyme Inhibitors; Fatty Acids; Inhibitory Concentration 50; Microbial Sensitivity Tests; Staphylococcus aureus; Streptomyces; Structure-Activity Relationship	2009
7-Phenylplatensimycin and 11-methyl-7-phenylplatensimycin: more potent analogs of platensimycin. Bioorganic & medicinal chemistry letters, 2010, Apr-01, Volume: 20, Issue:7 Topics: Adamantane; Aminobenzoates; Anilides; Anti-Bacterial Agents; Enterococcus; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Microbial Sensitivity Tests; Staphylococcus aureus; Structure-Activity Relationship	2010
An oxidative Prins-pinacol tandem process and its application to the synthesis of (-)-platensimycin. Chemistry (Weinheim an der Bergstrasse, Germany), 2010, Oct-04, Volume: 16, Issue:37 Topics: Adamantane; Aminobenzoates; Anilides; Biological Products; Combinatorial Chemistry Techniques; Molecular Structure; Oxidation-Reduction; Stereoisomerism	2010
A bismuth(III)-catalyzed Friedel-Crafts cyclization and stereocontrolled organocatalytic approach to (-)-platensimycin. Organic letters, 2010, Dec-03, Volume: 12, Issue:23 Topics: Adamantane; Aminobenzoates; Anilides; Bismuth; Catalysis; Cyclization; Molecular Structure; Stereoisomerism	2010
Concise formal total synthesis of platensimycin mediated by a stereoselective autoxidation and hydroxyl group directed conjugative reduction. Organic letters, 2010, Dec-17, Volume: 12, Issue:24 Topics: Adamantane; Alkylation; Aminobenzoates; Anilides; Hydroxyl Radical; Models, Molecular; Molecular Structure; Oxidation-Reduction; Stereoisomerism	2010
Platensimycin and platencin congeners from Streptomyces platensis. Journal of natural products, 2011, Mar-25, Volume: 74, Issue:3 Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Anti-Bacterial Agents; Cytochrome P-450 Enzyme System; Fatty Acid Synthase, Type II; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Structure; Polycyclic Compounds; Stereoisomerism; Streptomyces; Structure-Activity Relationship	2011
Dialkylamino-2,4-dihydroxybenzoic acids as easily synthesized analogues of platensimycin and platencin with comparable antibacterial properties. Chemistry (Weinheim an der Bergstrasse, Germany), 2011, Mar-14, Volume: 17, Issue:12 Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Anti-Bacterial Agents; Biological Products; Fatty Acid Synthases; Molecular Structure; Polycyclic Compounds	2011
Proteomic signature of fatty acid biosynthesis inhibition available for in vivo mechanism-of-action studies. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:6 Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Anti-Bacterial Agents; Bacillus subtilis; Bacterial Proteins; Drug Discovery; Fatty Acids; Polycyclic Compounds; Proteomics	2011
Antidiabetic and antisteatotic effects of the selective fatty acid synthase (FAS) inhibitor platensimycin in mouse models of diabetes. Proceedings of the National Academy of Sciences of the United States of America, 2011, Mar-29, Volume: 108, Issue:13 Topics: Adamantane; Aminobenzoates; Anilides; Animals; Anti-Infective Agents; Diabetes Mellitus; Disease Models, Animal; Fatty Acid Synthases; Fatty Acids; Fatty Liver; Glucose; Humans; Hypoglycemic Agents; Liver; Mice; Mice, Mutant Strains; Oxidation-Reduction; Sterols	2011
Highly substituted oxabicyclic derivatives from furan: synthesis of (±)-platensimycin. Organic letters, 2011, May-06, Volume: 13, Issue:9 Topics: Adamantane; Alkylation; Aminobenzoates; Anilides; Anti-Bacterial Agents; Bridged Bicyclo Compounds, Heterocyclic; Furans; Molecular Structure; Oxygen Compounds; Stereoisomerism; Streptomyces	2011
Dedicated ent-kaurene and ent-atiserene synthases for platensimycin and platencin biosynthesis. Proceedings of the National Academy of Sciences of the United States of America, 2011, Aug-16, Volume: 108, Issue:33 Topics: Adamantane; Alkyl and Aryl Transferases; Aminobenzoates; Aminophenols; Anilides; Anti-Bacterial Agents; Hypoglycemic Agents; Metabolic Networks and Pathways; Molecular Sequence Data; Polycyclic Compounds; Streptomyces	2011
Oxidative Prins-pinacol tandem process mediated by a hypervalent iodine reagent: scope, limitations, and applications. The Journal of organic chemistry, 2011, Nov-18, Volume: 76, Issue:22 Topics: Adamantane; Aminobenzoates; Anilides; Cyclization; Indicators and Reagents; Iodine; Molecular Structure; Oxidation-Reduction; Phenols; Spiro Compounds; Stereoisomerism	2011
Planar chiral (η6-arene)Cr(CO)3 containing carboxylic acid derivatives: synthesis and use in the preparation of organometallic analogues of the antibiotic platensimycin. Dalton transactions (Cambridge, England : 2003), 2012, Jan-07, Volume: 41, Issue:1 Topics: Adamantane; Aminobenzoates; Anilides; Anti-Bacterial Agents; Carboxylic Acids; Chromium; Coordination Complexes; Crystallography, X-Ray; Microbial Sensitivity Tests; Molecular Conformation; Organometallic Compounds; Stereoisomerism	2012
Synthesis and antimicrobial evaluation of novel platensimycin analogues. Archiv der Pharmazie, 2012, Volume: 345, Issue:8 Topics: Adamantane; Aminobenzoates; Anilides; Anti-Infective Agents; In Vitro Techniques; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship	2012
Platensimycin and platencin biosynthesis in Streptomyces platensis, showcasing discovery and characterization of novel bacterial diterpene synthases. Methods in enzymology, 2012, Volume: 515 Topics: Adamantane; Alkyl and Aryl Transferases; Aminobenzoates; Aminophenols; Anilides; Bacterial Proteins; Biosynthetic Pathways; Blotting, Southern; Computational Biology; Diterpenes; Electrophoresis, Polyacrylamide Gel; Fermentation; Gene Expression Regulation, Bacterial; Genes, Bacterial; Multigene Family; Mutagenesis; Polycyclic Compounds; Polyisoprenyl Phosphates; Streptomyces	2012
Expression of the platencin biosynthetic gene cluster in heterologous hosts yielding new platencin congeners. Journal of natural products, 2012, Dec-28, Volume: 75, Issue:12 Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Models, Biological; Multigene Family; Nuclear Magnetic Resonance, Biomolecular; Polycyclic Compounds; Stereoisomerism; Streptomyces	2012
Development of a semi-defined medium supporting production of platensimycin and platencin by Streptomyces platensis. The Journal of antibiotics, 2013, Volume: 66, Issue:2 Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Anti-Bacterial Agents; Culture Media; Fermentation; Polycyclic Compounds; Streptomyces	2013
A bifunctional Lewis acid induced cascade cyclization to the tricyclic core of ent-kaurenoids and its application to the formal synthesis of (±)-platensimycin. Organic letters, 2013, Feb-01, Volume: 15, Issue:3 Topics: Adamantane; Aminobenzoates; Anilides; Antidepressive Agents, Tricyclic; Catalysis; Combinatorial Chemistry Techniques; Cyclization; Diterpenes, Kaurane; Lewis Acids; Molecular Structure; Stereoisomerism	2013
Stereoselective approach to the racemic oxatetracyclic core of platensimycin. The Journal of organic chemistry, 2013, Mar-15, Volume: 78, Issue:6 Topics: Adamantane; Aminobenzoates; Anilides; Cyclization; Cycloaddition Reaction; Molecular Structure; Polycyclic Compounds; Stereoisomerism	2013
Formal syntheses of (±)-platensimycin and (±)-platencin via a dual-mode Lewis acid induced cascade cyclization approach. The Journal of organic chemistry, 2013, Aug-16, Volume: 78, Issue:16 Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Cyclization; Lewis Acids; Molecular Structure; Polycyclic Compounds; Stereoisomerism	2013
Development of a chemically defined medium for the production of the antibiotic platensimycin by Streptomyces platensis. Applied microbiology and biotechnology, 2013, Volume: 97, Issue:21 Topics: Adamantane; Aminobenzoates; Anilides; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Culture Media; Microbial Sensitivity Tests; Streptomyces	2013
Stereodivergent resolution of oxabicyclic ketones: preparation of key intermediates for platensimycin and other natural products. The Journal of organic chemistry, 2013, Oct-18, Volume: 78, Issue:20 Topics: Adamantane; Aminobenzoates; Anilides; Biological Products; Bridged Bicyclo Compounds; Ketones; Molecular Structure; Stereoisomerism	2013
Discovery of novel FabF ligands inspired by platensimycin by integrating structure-based design with diversity-oriented synthetic accessibility. Organic & biomolecular chemistry, 2014, Jan-21, Volume: 12, Issue:3 Topics: Acetyltransferases; Adamantane; Aminobenzoates; Anilides; Dose-Response Relationship, Drug; Drug Discovery; Enzyme Inhibitors; Escherichia coli Proteins; Fatty Acid Synthase, Type II; Ligands; Models, Molecular; Molecular Conformation; Structure-Activity Relationship	2014
Mechanisms of self-resistance in the platensimycin- and platencin-producing Streptomyces platensis MA7327 and MA7339 strains. Chemistry & biology, 2014, Mar-20, Volume: 21, Issue:3 Topics: Adamantane; Amino Acid Substitution; Aminobenzoates; Aminophenols; Anilides; Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; Drug Resistance, Bacterial; Fatty Acid Synthase, Type II; Microbial Sensitivity Tests; Molecular Sequence Data; Multigene Family; Polycyclic Compounds; Streptomyces	2014
Strain prioritization for natural product discovery by a high-throughput real-time PCR method. Journal of natural products, 2014, Oct-24, Volume: 77, Issue:10 Topics: Actinobacteria; Adamantane; Aminobenzoates; Aminophenols; Anilides; Biological Products; Molecular Structure; Polycyclic Compounds; Real-Time Polymerase Chain Reaction; Small Molecule Libraries	2014
Novel platensimycin derivatives with herbicidal activity. Pest management science, 2016, Volume: 72, Issue:3 Topics: Adamantane; Amides; Aminobenzoates; Anilides; Crops, Agricultural; Herbicides; Plants; Santonin	2016
A genetically amenable platensimycin- and platencin-overproducer as a platform for biosynthetic explorations: a showcase of PtmO4, a long-chain acyl-CoA dehydrogenase. Molecular bioSystems, 2015, Volume: 11, Issue:10 Topics: Acyl-CoA Dehydrogenase, Long-Chain; Adamantane; Aminobenzoates; Aminophenols; Anilides; Bacterial Proteins; Biosynthetic Pathways; Multigene Family; Mutation; Polycyclic Compounds; Streptomyces	2015
Membrane Affinity of Platensimycin and Its Dialkylamine Analogs. International journal of molecular sciences, 2015, Aug-04, Volume: 16, Issue:8 Topics: Adamantane; Aminobenzoates; Anilides; Anti-Infective Agents; Cell Membrane; Cell Membrane Permeability; Escherichia coli; Ion Channels	2015
Structures of Pseudomonas aeruginosa β-ketoacyl-(acyl-carrier-protein) synthase II (FabF) and a C164Q mutant provide templates for antibacterial drug discovery and identify a buried potassium ion and a ligand-binding site that is an artefact of the crysta Acta crystallographica. Section F, Structural biology communications, 2015, Volume: 71, Issue:Pt 8 Topics: Adamantane; Amino Acid Motifs; Aminobenzoates; Anilides; Anti-Bacterial Agents; Bacterial Proteins; Benzamides; Catalytic Domain; Cloning, Molecular; Crystallization; Crystallography, X-Ray; Drug Discovery; Escherichia coli; Fatty Acid Synthase, Type II; Gene Expression; Models, Molecular; Molecular Sequence Data; Mutation; Potassium; Protein Binding; Protein Structure, Secondary; Protein Subunits; Pseudomonas aeruginosa; Recombinant Fusion Proteins; Salicylates	2015
Titer improvement and pilot-scale production of platensimycin from Streptomyces platensis SB12026. Journal of industrial microbiology & biotechnology, 2016, Volume: 43, Issue:7 Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Anti-Bacterial Agents; Bioreactors; Culture Media; Fermentation; Industrial Microbiology; Pilot Projects; Polycyclic Compounds; Streptomyces	2016
Antibacterial sulfur-containing platensimycin and platencin congeners from Streptomyces platensis SB12029. Bioorganic & medicinal chemistry, 2016, 12-15, Volume: 24, Issue:24 Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Anti-Bacterial Agents; Biological Products; Microbial Sensitivity Tests; Micrococcus luteus; Polycyclic Compounds; Staphylococcus aureus; Streptomyces; Sulfur	2016
A Mutasynthetic Library of Platensimycin and Platencin Analogues. Organic letters, 2016, 09-16, Volume: 18, Issue:18 Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Molecular Structure; Polycyclic Compounds; Small Molecule Libraries; Stereoisomerism	2016
Biosynthetic Origin of the Ether Ring in Platensimycin. Journal of the American Chemical Society, 2016, 12-28, Volume: 138, Issue:51 Topics: Adamantane; Aminobenzoates; Anilides; Biocatalysis; Cytochrome P-450 Enzyme System; Diterpenes; Escherichia coli; Ether; Micrococcus luteus; Mutation; Staphylococcus	2016
In vivo instability of platensimycin and platencin: Synthesis and biological evaluation of urea- and carbamate-platensimycin. Bioorganic & medicinal chemistry, 2017, 03-15, Volume: 25, Issue:6 Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Animals; Anti-Bacterial Agents; Carbamates; Carbon-13 Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C57BL; Polycyclic Compounds; Proton Magnetic Resonance Spectroscopy; Urea	2017
Nutritional control of antibiotic production by Streptomyces platensis MA7327: importance of l-aspartic acid. The Journal of antibiotics, 2017, Volume: 70, Issue:7 Topics: Adamantane; Amino Acids; Aminobenzoates; Aminophenols; Anilides; Anti-Bacterial Agents; Aspartic Acid; Nucleic Acids; Polycyclic Compounds; Streptomyces; Vitamins	2017
N-Acylated Derivatives of Sulfamethoxazole Block Chlamydia Fatty Acid Synthesis and Interact with FabF. Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:10 Topics: Acylation; Adamantane; Aminobenzoates; Anilides; Animals; Anti-Bacterial Agents; Cell Line, Tumor; Cerulenin; Chlamydia Infections; Chlamydia trachomatis; Chlorocebus aethiops; Fatty Acid Synthase, Type II; Fatty Acid Synthesis Inhibitors; Fatty Acids; HeLa Cells; Humans; Sulfamethoxazole; Triclosan; Vero Cells	2017
Biomimetic Stereoselective Sulfa-Michael Addition Leads to Platensimycin and Platencin Sulfur Analogues against Methicillin-Resistant Staphylococcus aureus. Journal of natural products, 2018, 02-23, Volume: 81, Issue:2 Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Anti-Bacterial Agents; Biological Products; Biomimetics; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Polycyclic Compounds; Structure-Activity Relationship; Sulfur	2018
Biosynthesis of thiocarboxylic acid-containing natural products. Nature communications, 2018, 06-18, Volume: 9, Issue:1 Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Biological Products; Escherichia coli; Multigene Family; Polycyclic Compounds; Streptomyces; Sulfur	2018
Cytochrome P450-Catalyzed Hydroxylation Initiating Ether Formation in Platensimycin Biosynthesis. Journal of the American Chemical Society, 2018, 10-03, Volume: 140, Issue:39 Topics: Adamantane; Aminobenzoates; Anilides; Catalysis; Cyclization; Cytochrome P-450 Enzyme System; Escherichia coli; Ethers; Hydroxylation; Multigene Family; Spirulina; Stereoisomerism	2018
Semisynthesis of Platensimycin Derivatives with Antibiotic Activities in Mice via Suzuki-Miyaura Cross-Coupling Reactions. Journal of medicinal chemistry, 2018, 12-27, Volume: 61, Issue:24 Topics: Adamantane; Aminobenzoates; Anilides; Animals; Anti-Bacterial Agents; Disease Models, Animal; Male; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Docking Simulation; Peritonitis; Staphylococcal Infections	2018
Cryptic and Stereospecific Hydroxylation, Oxidation, and Reduction in Platensimycin and Platencin Biosynthesis. Journal of the American Chemical Society, 2019, 03-06, Volume: 141, Issue:9 Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Hydroxylation; Molecular Conformation; Oxidation-Reduction; Polycyclic Compounds; Stereoisomerism	2019
Evaluation of Platensimycin and Platensimycin-Inspired Thioether Analogues against Methicillin-Resistant Staphylococcus aureus in Topical and Systemic Infection Mouse Models. Molecular pharmaceutics, 2019, 07-01, Volume: 16, Issue:7 Topics: Adamantane; Aminobenzoates; Anilides; Animals; Anti-Bacterial Agents; Biofilms; Burns; Disease Models, Animal; Drug Resistance, Bacterial; Drug Stability; Fatty Acid Synthase, Type II; Fatty Acid Synthesis Inhibitors; Female; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microsomes; Peritonitis; Prodrugs; Staphylococcal Skin Infections; Sulfides; Treatment Outcome	2019
Late-Stage Functionalization of Platensimycin Leading to Multiple Analogues with Improved Antibacterial Activity in Vitro and in Vivo. Journal of medicinal chemistry, 2019, 07-25, Volume: 62, Issue:14 Topics: Adamantane; Aminobenzoates; Anilides; Animals; Anti-Bacterial Agents; Humans; Male; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred C57BL; Models, Molecular; Peritonitis; Small Molecule Libraries; Staphylococcal Infections; Staphylococcus	2019
Characterization and Crystal Structure of a Nonheme Diiron Monooxygenase Involved in Platensimycin and Platencin Biosynthesis. Journal of the American Chemical Society, 2019, 08-07, Volume: 141, Issue:31 Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Catalytic Domain; Crystallography, X-Ray; Hydroxylation; Iron; Mixed Function Oxygenases; Models, Molecular; Polycyclic Compounds	2019
Platensimycin-Encapsulated Poly(lactic- Bioconjugate chemistry, 2020, 05-20, Volume: 31, Issue:5 Topics: Adamantane; Aminobenzoates; Anilides; Animals; Anti-Bacterial Agents; Biofilms; Dendrimers; Drug Carriers; Methicillin-Resistant Staphylococcus aureus; Mice; Nanoparticles; Polyamines; Polylactic Acid-Polyglycolic Acid Copolymer	2020
Rapid, Selective, and Sensitive Method for Semitargeted Discovery of Congeneric Natural Products by Liquid Chromatography Tandem Mass Spectrometry. Journal of natural products, 2021, 03-26, Volume: 84, Issue:3 Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Biological Products; Chromatography, Liquid; High-Throughput Screening Assays; Molecular Structure; Polycyclic Compounds; Streptomyces; Structure-Activity Relationship; Tandem Mass Spectrometry	2021
Nanoparticle-Hydrogel Systems Containing Platensimycin for Local Treatment of Methicillin-Resistant Molecular pharmaceutics, 2021, 11-01, Volume: 18, Issue:11 Topics: Adamantane; Aminobenzoates; Anilides; Animals; Biofilms; Delayed-Action Preparations; Disease Models, Animal; Drug Liberation; Humans; Hydrogels; Male; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Nanoparticle Drug Delivery System; Polyamines; Staphylococcal Skin Infections; Wound Healing; Wound Infection	2021
Lipopeptide surfactin ameliorates the cell uptake of platensimycin and enhances its therapeutic effect on treatment of MRSA skin infection. The Journal of antimicrobial chemotherapy, 2022, 09-30, Volume: 77, Issue:10 Topics: Adamantane; Aminobenzoates; Anilides; Animals; Anti-Bacterial Agents; Cellulitis; Lipopeptides; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Propidium; Skin Diseases, Infectious	2022
Platensimycin-berberine chloride co-amorphous drug system: Sustained release and prolonged half-life. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2022, Volume: 179 Topics: Adamantane; Aminobenzoates; Anilides; Animals; Anti-Bacterial Agents; Berberine; Calorimetry, Differential Scanning; Chlorides; Delayed-Action Preparations; Drug Stability; Fatty Acid Synthases; Half-Life; Methicillin-Resistant Staphylococcus aureus; Powders; Rats; Solubility; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction	2022
Bioinspired Synthesis of Platensimycin from Natural Organic letters, 2023, 07-28, Volume: 25, Issue:29 Topics: Adamantane; Aminobenzoates; Diterpenes	2023