Page last updated: 2024-08-21

adamantane and platencin

adamantane has been researched along with platencin in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (14.71)29.6817
2010's28 (82.35)24.3611
2020's1 (2.94)2.80

Authors

AuthorsStudies
Capuano, B; Crosby, IT; Khakham, Y; Manallack, DT1
Burgess, B; Herath, KB; Jayasuriya, H; Ondeyka, JG; Singh, SB; Wang, J; Zhang, C; Zink, DL1
Rutjes, FP; Schaapman, MC; van Delft, FL; Waalboer, DC1
Peterson, RM; Rajski, SR; Shen, B; Smanski, MJ1
Becker, JW; Herath, KB; Jayasuriya, H; Ondeyka, JG; Parthasarathy, G; Singh, SB; Soisson, SM; Wang, J; Zhang, C; Zink, DL1
Chen, Y; Shen, B; Smanski, MJ1
Kaliappan, KP; Palanichamy, K1
Dietrich, L; Dorso, K; Gailliot, FP; Ha, SN; Hesse, M; Lester, M; Motyl, M; Ondeyka, J; Singh, SB; Wang, J; Zhang, C1
Burgess, B; Dietrich, L; Guan, Z; Ha, SN; Herath, K; Jayasuriya, H; Ondeyka, J; Singh, SB; Wang, J; Zhang, C; Zink, DL1
Sintim, HO; Wang, J1
Albrecht, D; Bandow, JE; Chen, DY; Metzler-Nolte, N; Nicolaou, KC; Patra, M; Wenzel, M1
Ahmed, I; Hussain, H; Krohn, K; Saleem, M; van Ree, T1
Casper, J; Chen, Y; Lin, S; Peterson, RM; Rajski, SR; Shen, B; Smanski, MJ; Wendt-Pienkowski, E; Yu, Z1
Demain, AL; Martens, E1
Peterson, RM; Shen, B; Smanski, MJ1
Casper, J; Peterson, RM; Rajski, SR; Shen, B; Smanski, MJ; Yu, Z1
Aluotto, S; Demain, AL; Falzone, M; Gullo, V; Maggio, C; Mukherjee, A; Tynan, H1
Cheng, GJ; He, S; Lee, CS; Yang, W; Zhang, X; Zhou, C; Zhu, L1
Huang, T; Peterson, RM; Rudolf, JD; Shen, B; Smanski, MJ1
Duan, Y; Huang, T; Huang, Y; Jiang, Y; Lohman, JR; Rudolf, JD; Shen, B; Teng, Q; Xie, G; Xie, P; Yang, D; Zhao, LX; Zhu, X1
Dong, LB; Huang, T; Rudolf, JD; Shen, B1
Liang, J; Liu, Y; Shang, R; Wang, J; Yi, Y1
Duan, Y; Huang, Y; Liu, L; Lu, S; Pan, J; Shen, B; Shi, J; Yang, D; Zhu, X1
Dong, LB; Rudolf, JD; Shen, B3
Cameron, MD; Dong, LB; Lin, L; Rudolf, JD; Ruiz, C; Shen, B1
Crespo, E; Demain, AL; Falzone, M; Gelber, M; Gullo, V; Jones, K; Khan, G; Komal, R; Korn, VL; Nayda, V; Patel, A; Patel, K; Patel, M; Perkins, C; Ravin, A; Rudolf, JD; Scheffler, R; Shen, B; Siddiqui, S; Stenger, D; Yu, E1
Deng, Y; Duan, Y; Huang, Y; Kang, D; Liang, H; Qiu, L; Shen, B; Tian, K; Wen, Z; Zhu, X1
Deng, Y; Dong, LB; Duan, Y; He, CQ; Houk, KN; Huang, Y; Kang, D; Rudolf, JD; Shen, B; Wang, N1
Adhikari, A; Shen, B; Teijaro, CN1
Cepeda, AJ; Deng, MR; Dong, LB; Kalkreuter, E; Renata, H; Rudolf, JD; Shen, B; Zhang, X1
Cepeda, AJ; Chang, C; Deng, MR; Dong, LB; Joachimiak, A; Kalkreuter, E; Liu, YC; Phillips, GN; Rudolf, JD; Shen, B1
Attygalle, AB; Genilloud, O; González, I; Herath, KB; Previs, SF; Roddy, TP; Singh, SB1

Reviews

8 review(s) available for adamantane and platencin

ArticleYear
Platensimycin: a promising antimicrobial targeting fatty acid synthesis.
    Current medicinal chemistry, 2008, Volume: 15, Issue:7

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Adamantane; Aminobenzoates; Aminophenols; Anilides; Animals; Anti-Infective Agents; Fatty Acids; Humans; Molecular Structure; Polycyclic Compounds; Structure-Activity Relationship

2008
Improvement of secondary metabolite production in Streptomyces by manipulating pathway regulation.
    Applied microbiology and biotechnology, 2010, Volume: 86, Issue:1

    Topics: Adamantane; Aminobenzoates; Aminoglycosides; Aminophenols; Anilides; Anti-Infective Agents; Bacterial Proteins; Biotechnology; Enediynes; Fermentation; Gene Expression Regulation, Bacterial; Genetic Engineering; Polycyclic Compounds; Streptomyces

2010
Discovery and syntheses of "superbug challengers"-platensimycin and platencin.
    Chemistry, an Asian journal, 2010, Apr-01, Volume: 5, Issue:4

    Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Anti-Infective Agents; Drug Discovery; Drug Resistance, Multiple, Bacterial; Fatty Acid Synthesis Inhibitors; Polycyclic Compounds

2010
Platensimycin and its relatives: a recent story in the struggle to develop new naturally derived antibiotics.
    Natural product reports, 2011, Volume: 28, Issue:9

    Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Anti-Bacterial Agents; Biological Products; Drug Design; Drug Resistance, Multiple; Enterococcus faecalis; Methicillin-Resistant Staphylococcus aureus; Polycyclic Compounds; Streptococcus pneumoniae; Structure-Activity Relationship

2011
Platensimycin and platencin: promising antibiotics for future application in human medicine.
    The Journal of antibiotics, 2011, Volume: 64, Issue:11

    Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Anti-Bacterial Agents; Fatty Acids; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Lipid Metabolism; Models, Molecular; Molecular Structure; Polycyclic Compounds; Streptomyces

2011
Review of Platensimycin and Platencin: Inhibitors of β-Ketoacyl-acyl Carrier Protein (ACP) Synthase III (FabH).
    Molecules (Basel, Switzerland), 2015, Sep-03, Volume: 20, Issue:9

    Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Anti-Bacterial Agents; Bacterial Proteins; Drug Resistance, Bacterial; Fatty Acid Synthase, Type II; Molecular Structure; Polycyclic Compounds; Streptomyces

2015
Platensimycin and platencin: Inspirations for chemistry, biology, enzymology, and medicine.
    Biochemical pharmacology, 2017, 06-01, Volume: 133

    Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Animals; Anti-Infective Agents; Communicable Diseases; Humans; Polycyclic Compounds; Protein Structure, Secondary; Protein Structure, Tertiary; Structure-Activity Relationship

2017
Challenges and opportunities for natural product discovery, production, and engineering in native producers versus heterologous hosts.
    Journal of industrial microbiology & biotechnology, 2019, Volume: 46, Issue:3-4

    Topics: Adamantane; Aminobenzoates; Aminoglycosides; Aminophenols; Anilides; Bacterial Proteins; Biological Products; Biosynthetic Pathways; Drug Discovery; Enediynes; Gene Expression Regulation, Bacterial; Genes, Bacterial; Lactams; Macrolides; Metabolic Engineering; Multigene Family; Piperidones; Polycyclic Compounds; Protein Conformation; Sequence Analysis, DNA; Streptomyces; Thiazoles; Thiones

2019

Other Studies

26 other study(ies) available for adamantane and platencin

ArticleYear
Structure and semisynthesis of platensimide A, produced by Streptomyces platensis.
    Organic letters, 2008, May-01, Volume: 10, Issue:9

    Topics: Adamantane; Aminobenzoates; Aminobutyrates; Aminophenols; Anilides; Anti-Bacterial Agents; Bacteria; Bridged-Ring Compounds; Microbial Sensitivity Tests; Molecular Structure; Polycyclic Compounds; Streptomyces

2008
High-pressure entry into platencin.
    Angewandte Chemie (International ed. in English), 2008, Volume: 47, Issue:35

    Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Anti-Bacterial Agents; Crystallography, X-Ray; Molecular Structure; Polycyclic Compounds; Pressure; Stereoisomerism

2008
Engineered Streptomyces platensis strains that overproduce antibiotics platensimycin and platencin.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:4

    Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Anti-Bacterial Agents; Fermentation; Genetic Engineering; Hydro-Lyases; Multigene Family; Polycyclic Compounds; Polymerase Chain Reaction; Streptomyces

2009
Isolation, enzyme-bound structure and antibacterial activity of platencin A1 from Streptomyces platensis.
    Bioorganic & medicinal chemistry letters, 2009, Aug-15, Volume: 19, Issue:16

    Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Anti-Bacterial Agents; Crystallography, X-Ray; Molecular Conformation; Polycyclic Compounds; Streptomyces; Structure-Activity Relationship

2009
Isolation, structure and biological activities of platencin A(2)-A(4) from Streptomyces platensis.
    Bioorganic & medicinal chemistry, 2010, Apr-01, Volume: 18, Issue:7

    Topics: Adamantane; Aminobenzoates; Aminophenols; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Fermentation; Haemophilus influenzae; Hydroxylation; Indicators and Reagents; Mass Spectrometry; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Polycyclic Compounds; Spectrophotometry, Ultraviolet; Staphylococcus aureus; Streptomyces; Structure-Activity Relationship

2010
Platensimycin and platencin congeners from Streptomyces platensis.
    Journal of natural products, 2011, Mar-25, Volume: 74, Issue:3

    Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Anti-Bacterial Agents; Cytochrome P-450 Enzyme System; Fatty Acid Synthase, Type II; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Structure; Polycyclic Compounds; Stereoisomerism; Streptomyces; Structure-Activity Relationship

2011
Dialkylamino-2,4-dihydroxybenzoic acids as easily synthesized analogues of platensimycin and platencin with comparable antibacterial properties.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2011, Mar-14, Volume: 17, Issue:12

    Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Anti-Bacterial Agents; Biological Products; Fatty Acid Synthases; Molecular Structure; Polycyclic Compounds

2011
Proteomic signature of fatty acid biosynthesis inhibition available for in vivo mechanism-of-action studies.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:6

    Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Anti-Bacterial Agents; Bacillus subtilis; Bacterial Proteins; Drug Discovery; Fatty Acids; Polycyclic Compounds; Proteomics

2011
Dedicated ent-kaurene and ent-atiserene synthases for platensimycin and platencin biosynthesis.
    Proceedings of the National Academy of Sciences of the United States of America, 2011, Aug-16, Volume: 108, Issue:33

    Topics: Adamantane; Alkyl and Aryl Transferases; Aminobenzoates; Aminophenols; Anilides; Anti-Bacterial Agents; Hypoglycemic Agents; Metabolic Networks and Pathways; Molecular Sequence Data; Polycyclic Compounds; Streptomyces

2011
Platensimycin and platencin biosynthesis in Streptomyces platensis, showcasing discovery and characterization of novel bacterial diterpene synthases.
    Methods in enzymology, 2012, Volume: 515

    Topics: Adamantane; Alkyl and Aryl Transferases; Aminobenzoates; Aminophenols; Anilides; Bacterial Proteins; Biosynthetic Pathways; Blotting, Southern; Computational Biology; Diterpenes; Electrophoresis, Polyacrylamide Gel; Fermentation; Gene Expression Regulation, Bacterial; Genes, Bacterial; Multigene Family; Mutagenesis; Polycyclic Compounds; Polyisoprenyl Phosphates; Streptomyces

2012
Expression of the platencin biosynthetic gene cluster in heterologous hosts yielding new platencin congeners.
    Journal of natural products, 2012, Dec-28, Volume: 75, Issue:12

    Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Models, Biological; Multigene Family; Nuclear Magnetic Resonance, Biomolecular; Polycyclic Compounds; Stereoisomerism; Streptomyces

2012
Development of a semi-defined medium supporting production of platensimycin and platencin by Streptomyces platensis.
    The Journal of antibiotics, 2013, Volume: 66, Issue:2

    Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Anti-Bacterial Agents; Culture Media; Fermentation; Polycyclic Compounds; Streptomyces

2013
Formal syntheses of (±)-platensimycin and (±)-platencin via a dual-mode Lewis acid induced cascade cyclization approach.
    The Journal of organic chemistry, 2013, Aug-16, Volume: 78, Issue:16

    Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Cyclization; Lewis Acids; Molecular Structure; Polycyclic Compounds; Stereoisomerism

2013
Mechanisms of self-resistance in the platensimycin- and platencin-producing Streptomyces platensis MA7327 and MA7339 strains.
    Chemistry & biology, 2014, Mar-20, Volume: 21, Issue:3

    Topics: Adamantane; Amino Acid Substitution; Aminobenzoates; Aminophenols; Anilides; Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; Drug Resistance, Bacterial; Fatty Acid Synthase, Type II; Microbial Sensitivity Tests; Molecular Sequence Data; Multigene Family; Polycyclic Compounds; Streptomyces

2014
Strain prioritization for natural product discovery by a high-throughput real-time PCR method.
    Journal of natural products, 2014, Oct-24, Volume: 77, Issue:10

    Topics: Actinobacteria; Adamantane; Aminobenzoates; Aminophenols; Anilides; Biological Products; Molecular Structure; Polycyclic Compounds; Real-Time Polymerase Chain Reaction; Small Molecule Libraries

2014
A genetically amenable platensimycin- and platencin-overproducer as a platform for biosynthetic explorations: a showcase of PtmO4, a long-chain acyl-CoA dehydrogenase.
    Molecular bioSystems, 2015, Volume: 11, Issue:10

    Topics: Acyl-CoA Dehydrogenase, Long-Chain; Adamantane; Aminobenzoates; Aminophenols; Anilides; Bacterial Proteins; Biosynthetic Pathways; Multigene Family; Mutation; Polycyclic Compounds; Streptomyces

2015
Titer improvement and pilot-scale production of platensimycin from Streptomyces platensis SB12026.
    Journal of industrial microbiology & biotechnology, 2016, Volume: 43, Issue:7

    Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Anti-Bacterial Agents; Bioreactors; Culture Media; Fermentation; Industrial Microbiology; Pilot Projects; Polycyclic Compounds; Streptomyces

2016
Antibacterial sulfur-containing platensimycin and platencin congeners from Streptomyces platensis SB12029.
    Bioorganic & medicinal chemistry, 2016, 12-15, Volume: 24, Issue:24

    Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Anti-Bacterial Agents; Biological Products; Microbial Sensitivity Tests; Micrococcus luteus; Polycyclic Compounds; Staphylococcus aureus; Streptomyces; Sulfur

2016
A Mutasynthetic Library of Platensimycin and Platencin Analogues.
    Organic letters, 2016, 09-16, Volume: 18, Issue:18

    Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Molecular Structure; Polycyclic Compounds; Small Molecule Libraries; Stereoisomerism

2016
In vivo instability of platensimycin and platencin: Synthesis and biological evaluation of urea- and carbamate-platensimycin.
    Bioorganic & medicinal chemistry, 2017, 03-15, Volume: 25, Issue:6

    Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Animals; Anti-Bacterial Agents; Carbamates; Carbon-13 Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C57BL; Polycyclic Compounds; Proton Magnetic Resonance Spectroscopy; Urea

2017
Nutritional control of antibiotic production by Streptomyces platensis MA7327: importance of l-aspartic acid.
    The Journal of antibiotics, 2017, Volume: 70, Issue:7

    Topics: Adamantane; Amino Acids; Aminobenzoates; Aminophenols; Anilides; Anti-Bacterial Agents; Aspartic Acid; Nucleic Acids; Polycyclic Compounds; Streptomyces; Vitamins

2017
Biomimetic Stereoselective Sulfa-Michael Addition Leads to Platensimycin and Platencin Sulfur Analogues against Methicillin-Resistant Staphylococcus aureus.
    Journal of natural products, 2018, 02-23, Volume: 81, Issue:2

    Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Anti-Bacterial Agents; Biological Products; Biomimetics; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Polycyclic Compounds; Structure-Activity Relationship; Sulfur

2018
Biosynthesis of thiocarboxylic acid-containing natural products.
    Nature communications, 2018, 06-18, Volume: 9, Issue:1

    Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Biological Products; Escherichia coli; Multigene Family; Polycyclic Compounds; Streptomyces; Sulfur

2018
Cryptic and Stereospecific Hydroxylation, Oxidation, and Reduction in Platensimycin and Platencin Biosynthesis.
    Journal of the American Chemical Society, 2019, 03-06, Volume: 141, Issue:9

    Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Hydroxylation; Molecular Conformation; Oxidation-Reduction; Polycyclic Compounds; Stereoisomerism

2019
Characterization and Crystal Structure of a Nonheme Diiron Monooxygenase Involved in Platensimycin and Platencin Biosynthesis.
    Journal of the American Chemical Society, 2019, 08-07, Volume: 141, Issue:31

    Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Catalytic Domain; Crystallography, X-Ray; Hydroxylation; Iron; Mixed Function Oxygenases; Models, Molecular; Polycyclic Compounds

2019
Rapid, Selective, and Sensitive Method for Semitargeted Discovery of Congeneric Natural Products by Liquid Chromatography Tandem Mass Spectrometry.
    Journal of natural products, 2021, 03-26, Volume: 84, Issue:3

    Topics: Adamantane; Aminobenzoates; Aminophenols; Anilides; Biological Products; Chromatography, Liquid; High-Throughput Screening Assays; Molecular Structure; Polycyclic Compounds; Streptomyces; Structure-Activity Relationship; Tandem Mass Spectrometry

2021