adamantane has been researched along with indazoles in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (6.90) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 21 (72.41) | 24.3611 |
| 2020's | 6 (20.69) | 2.80 |
| Authors | Studies |
|---|---|
| Bloomquist, W; Calligaro, DA; Cohen, I; Cohen, ML; Schaus, JM; Susemichel, AD; Thompson, DC | 1 |
| Bloomquist, WE; Calligaro, DO; Cohen, ML; Schaus, JM; Susemichel, AD; Thompson, DC | 1 |
| Chou, KC | 1 |
| Dalsgaard, PW; Holm, NB; Linnet, K; Pedersen, AJ | 1 |
| Holm, NB; Linnet, K; Nielsen, LM | 1 |
| Castelli, MP; Davidson, C; De Luca, MA; Di Chiara, G; Kellett, K; Loi, B; Martorelli, M; Miliano, C; Porcu, A; Schifano, F; Stair, JL | 1 |
| Berg, JD; Ford, LT | 2 |
| Argo, A; Brancato, A; Cannizzaro, C; Casagni, E; Froldi, R; Fumagalli, L; Gambaro, V; Malta, G; Procaccianti, P; Roda, G; Valoti, E | 1 |
| Alessio, E; Arcangeli, A; Balducci, G; Battistin, F; Messori, L; Pillozzi, S; Scaletti, F | 1 |
| Hua, Z; Jia, W; Li, T; Liu, C; Meng, X; Qian, Z | 1 |
| Dunne, SJ; Rosengren-Holmberg, JP | 1 |
| Abouchedid, R; Archer, JR; Dargan, PI; Dines, A; Ho, JH; Hudson, S; Wood, DM | 1 |
| Borea, PA; Canazza, I; De Luca, MA; Di Rosa, F; Fantinati, A; Gregori, A; Margiani, G; Marti, M; Ossato, A; Rimondo, C; Serpelloni, G; Trapella, C; Varani, K; Vincenzi, F | 1 |
| Borg, D; Stripp, R; Tverdovsky, A | 1 |
| Asada, A; Doi, T; Sawabe, Y; Tagami, T; Takeda, A | 1 |
| Fantegrossi, WE; Tai, S | 1 |
| Abouchedid, R; Archer, JRH; Bailey, G; Dargan, PI; Dines, A; Ho, JH; Hudson, S; Sadones, N; Stove, CP; Thurtle, N; Wood, DM; Wood, M; Yamamoto, T | 1 |
| Banister, SD; Connor, M; Kassiou, M; Longworth, M | 1 |
| Garvin, D; Grabenauer, M; Moore, KN; Thomas, BF | 1 |
| Assemat, G; Balayssac, S; Dubocq, F; Gilard, V; Lamoureux, C; Malet-Martino, M | 1 |
| Abudayyak, M; Celiksoz, M; Özhan, G; Oztas, E | 1 |
| Appolonova, S; Arfè, R; Bertolucci, C; Bilel, S; Fantinati, A; Frisoni, P; Grignolio, S; Marti, M; Morbiato, E; Neri, M; Savchuk, S; Tagliaro, F; Tirri, M | 1 |
| Bush, JM; Cabanlong, CV; Fantegrossi, WE; Fujiwara, R; Fukuda, S; Gogoi, J; Jackson, BK; McCain, K; Pinson, A; Prather, PL; Radominska-Pandya, A; Shoeib, A; Yarbrough, AL | 1 |
| Boysen, G; Fantegrossi, WE; Miller, GP; Pinson, AO; Pouncey, DL; Prather, PL; Radominska-Pandya, A; Schleiff, MA | 1 |
| Appolonova, SA; Brito, A; La Frano, MR; Markin, PA; Moskaleva, NE; Savitskii, MV; Tagliaro, F | 1 |
| Baek, SY; Choi, HS; Kim, H; Kim, NS; Lee, JH; Lim, NY | 1 |
| Abdelkader, A; Al-Jumeily, D; Assi, S; Coombs, T; Tang, L | 1 |
2 review(s) available for adamantane and indazoles
| Article | Year |
|---|---|
Graphic rule for drug metabolism systems.
Topics: Adamantane; Animals; Benzimidazoles; Enzymes; Humans; Indazoles; Models, Theoretical; Nitriles; Pharmaceutical Preparations; Protein Folding; Purines; Pyrrolidines; Roscovitine; Time Factors; Vildagliptin | 2010 |
Pharmacological and Toxicological Effects of Synthetic Cannabinoids and Their Metabolites.
Topics: Adamantane; Animals; Benzoxazines; Cannabinoid Receptor Agonists; Cannabinoids; Cytochrome P-450 Enzyme System; Dronabinol; Drug Interactions; Humans; Indazoles; Indoles; Morpholines; Naphthalenes; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2 | 2017 |
27 other study(ies) available for adamantane and indazoles
| Article | Year |
|---|---|
LY353433, a potent, orally effective, long-acting 5-HT(4) receptor antagonist: comparison to cisapride and RS23597-190.
Topics: Adamantane; Administration, Oral; Aminobenzoates; Animals; Cisapride; Esophagus; Female; In Vitro Techniques; Indazoles; Male; Muscle Relaxation; para-Aminobenzoates; Piperidines; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Rats, Wistar; Serotonin Antagonists | 1996 |
Synthesis and structure-activity relationships of potent and orally active 5-HT4 receptor antagonists: indazole and benzimidazolone derivatives.
Topics: Adamantane; Administration, Oral; Adrenergic alpha-Antagonists; Animals; Aorta; Brain; Drug Evaluation, Preclinical; Esophagus; Guinea Pigs; Ileum; In Vitro Techniques; Indazoles; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Adrenergic, alpha-1; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Receptors, Serotonin, 5-HT4; Serotonin Antagonists; Structure-Activity Relationship | 1998 |
Metabolites of 5F-AKB-48, a synthetic cannabinoid receptor agonist, identified in human urine and liver microsomal preparations using liquid chromatography high-resolution mass spectrometry.
Topics: Adamantane; Cannabinoid Receptor Agonists; Chromatography, Liquid; Designer Drugs; Humans; Indazoles; Mass Spectrometry; Microsomes, Liver | 2015 |
CYP3A4 Mediates Oxidative Metabolism of the Synthetic Cannabinoid AKB-48.
Topics: Adamantane; Cannabinoids; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Indazoles; Microsomes, Liver; Oxidation-Reduction | 2015 |
Native CB1 receptor affinity, intrinsic activity and accumbens shell dopamine stimulant properties of third generation SPICE/K2 cannabinoids: BB-22, 5F-PB-22, 5F-AKB-48 and STS-135.
Topics: Adamantane; Animals; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Central Nervous System Stimulants; Dopamine Agents; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Indazoles; Indoles; Male; Mice, Inbred C57BL; Mice, Knockout; Molecular Structure; Naphthalenes; Nucleus Accumbens; Piperidines; Prefrontal Cortex; Pyrazoles; Quinolines; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1 | 2016 |
1-Adamantylamine a simple urine marker for screening for third generation adamantyl-type synthetic cannabinoids by ultra-performance liquid chromatography tandem mass spectrometry.
Topics: Adamantane; Adult; Amantadine; Cannabinoids; Chromatography, High Pressure Liquid; Female; Humans; Illicit Drugs; Indazoles; Indoles; Limit of Detection; Male; Substance Abuse Detection; Tandem Mass Spectrometry; United Kingdom | 2016 |
Behavioural and pharmacological characterization of a novel cannabinomimetic adamantane-derived indole, APICA, and considerations on the possible misuse as a psychotropic spice abuse, in C57bl/6J mice.
Topics: Adamantane; Animals; Cannabinoids; Designer Drugs; Dose-Response Relationship, Drug; Female; Forensic Medicine; Indazoles; Mice; Mice, Inbred C57BL; Nociception | 2016 |
Water-soluble Ru(II)- and Ru(III)-halide-PTA complexes (PTA=1,3,5-triaza-7-phosphaadamantane): Chemical and biological properties.
Topics: Adamantane; Antineoplastic Agents; Bromides; Cell Line, Tumor; Cell Survival; Chlorides; Coordination Complexes; Cytochromes c; Filaggrin Proteins; HCT116 Cells; Humans; Hydrogen-Ion Concentration; Imidazoles; Indazoles; Inhibitory Concentration 50; Ligands; Oligonucleotides; Organometallic Compounds; Organophosphorus Compounds; Protons; Ribonuclease, Pancreatic; Ruthenium; Solubility; Structure-Activity Relationship; Water | 2016 |
Identification of three cannabimimetic indazole and pyrazole derivatives, APINACA 2H-indazole analogue, AMPPPCA, and 5F-AMPPPCA.
Topics: Adamantane; Cannabinoids; Chromatography, Liquid; Gas Chromatography-Mass Spectrometry; Illicit Drugs; Indazoles; Magnetic Resonance Spectroscopy; Mass Spectrometry; Psychotropic Drugs; Pyrazoles | 2017 |
Analysis of legal high materials by ultra-performance liquid chromatography with time of flight mass spectrometry as part of a toxicology vigilance system: what are the most popular novel psychoactive substances in the UK?
Topics: Adamantane; Chromatography, High Pressure Liquid; Humans; Illicit Drugs; Indazoles; Liquid-Liquid Extraction; Methamphetamine; Methylphenidate; Nicotiana; Plants, Medicinal; Powders; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thiophenes | 2017 |
Schedules of Controlled Substances: Placement of UR-144, XLR11, and AKB48 into Schedule I. Final rule.
Topics: Adamantane; Cannabinoids; Drug and Narcotic Control; Humans; Indazoles; Indoles; United States | 2016 |
Quantification of synthetic cannabinoids in herbal smoking blends using NMR.
Topics: Adamantane; Cannabinoids; Humans; Illicit Drugs; Indazoles; Indoles; Magnetic Resonance Spectroscopy; Methanol; Plant Preparations; Smoking, Non-Tobacco Products; Solvents; Sweden | 2017 |
Acute Toxicity Associated with Use of 5F-Derivations of Synthetic Cannabinoid Receptor Agonists with Analytical Confirmation.
Topics: Adamantane; Administration, Intravenous; Anti-Anxiety Agents; Cannabinoid Receptor Agonists; Citalopram; Female; Fluoxetine; Hallucinations; Hallucinogens; Humans; Indazoles; Indoles; Lysergic Acid Diethylamide; Midazolam; Psychomotor Agitation; Quinolines; Seizures; Tachycardia; Time Factors; Young Adult | 2016 |
Effect of the novel synthetic cannabinoids AKB48 and 5F-AKB48 on "tetrad", sensorimotor, neurological and neurochemical responses in mice. In vitro and in vivo pharmacological studies.
Topics: Adamantane; Aggression; Animals; Behavior, Animal; Binding, Competitive; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cannabis; Catalepsy; Dopamine; Dronabinol; Humans; In Vitro Techniques; Indazoles; Indoles; Male; Mice; Motor Activity; Naphthalenes; Nucleus Accumbens; Pain Threshold; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Reflex, Abnormal; Seizures | 2016 |
A Fast and Comprehensive Analysis of 32 Synthetic Cannabinoids Using Agilent Triple Quadrupole LC-MS-MS.
Topics: 2-Propanol; Adamantane; Butanes; Cannabinoids; Chromatography, Liquid; Humans; Illicit Drugs; Indazoles; Indoles; Liquid-Liquid Extraction; Quinolines; Reproducibility of Results; Substance Abuse Detection; Tandem Mass Spectrometry | 2017 |
Isomeric discrimination of synthetic cannabinoids by GC-EI-MS: 1-adamantyl and 2-adamantyl isomers of N-adamantyl carboxamides.
Topics: Adamantane; Cannabinoids; Gas Chromatography-Mass Spectrometry; Illicit Drugs; Indazoles; Indoles; Isomerism; Spectrometry, Mass, Electrospray Ionization | 2017 |
Analytical confirmation of synthetic cannabinoids in a cohort of 179 presentations with acute recreational drug toxicity to an Emergency Department in London, UK in the first half of 2015.
Topics: Adamantane; Adolescent; Adult; Aged; Cannabinoid Receptor Antagonists; Cohort Studies; Drug Overdose; Emergency Service, Hospital; Female; Humans; Illicit Drugs; Indazoles; Indoles; London; Male; Middle Aged; Prospective Studies; Substance Abuse Detection; Tandem Mass Spectrometry; Valine; Young Adult | 2017 |
Synthesis and Pharmacological Profiling of the Metabolites of Synthetic Cannabinoid Drugs APICA, STS-135, ADB-PINACA, and 5F-ADB-PINACA.
Topics: Adamantane; Cannabinoids; Humans; Indazoles; Indoles; Membrane Potentials; Molecular Structure; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2 | 2017 |
Identification of Eight Synthetic Cannabinoids, Including 5F-AKB48 in Seized Herbal Products Using DART-TOF-MS and LC-QTOF-MS as Nontargeted Screening Methods.
Topics: Adamantane; Cannabinoids; Chromatography, Liquid; Designer Drugs; Humans; Illicit Drugs; Indazoles; Indoles; Mass Spectrometry; Naphthalenes; Plant Preparations | 2017 |
Screening of "spice" herbal mixtures: From high-field to low-field proton NMR.
Topics: Adamantane; Anisoles; Cannabinoids; Designer Drugs; Humans; Indazoles; Indoles; Magnetic Resonance Spectroscopy; Naphthalenes | 2017 |
Inflammation and oxidative stress are key mediators in AKB48-induced neurotoxicity in vitro.
Topics: Adamantane; Cannabinoids; Cell Line, Tumor; Humans; Indazoles; Inflammation; Interleukin-6; Mitogen-Activated Protein Kinase 8; Neurotoxicity Syndromes; Oxidative Stress; Reactive Oxygen Species; Tumor Necrosis Factor-alpha | 2019 |
Potential of the zebrafish model for the forensic toxicology screening of NPS: A comparative study of the effects of APINAC and methiopropamine on the behavior of zebrafish larvae and mice.
Topics: Adamantane; Animals; Behavior, Animal; Drug Evaluation, Preclinical; Forensic Toxicology; Indazoles; Male; Methamphetamine; Mice, Inbred ICR; Psychotropic Drugs; Thiophenes; Zebrafish | 2020 |
Metabolism, CB1 cannabinoid receptor binding and in vivo activity of synthetic cannabinoid 5F-AKB48: Implications for toxicity.
Topics: Adamantane; Animals; Cannabinoid Receptor Antagonists; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Female; Humans; Indazoles; Male; Mice; Mice, Inbred C57BL; Microsomes, Liver; Oxidation-Reduction; Polymorphism, Genetic; Protein Binding; Receptor, Cannabinoid, CB1; Recombinant Proteins; Rimonabant; Sex Factors | 2020 |
Significance of Competing Metabolic Pathways for 5F-APINACA Based on Quantitative Kinetics.
Topics: Adamantane; Cannabinoids; Humans; Indazoles; Kinetics; Metabolic Networks and Pathways; Microsomes, Liver | 2020 |
Short- and long-term exposures of the synthetic cannabinoid 5F-APINAC induce metabolomic alterations associated with neurotransmitter systems and embryotoxicity confirmed by teratogenicity in zebrafish.
Topics: Adamantane; Animals; Cannabinoids; Indazoles; Metabolome; Synaptic Transmission; Teratogenesis; Zebrafish | 2021 |
Application of a simultaneous screening method for the detection of new psychoactive substances in various matrix samples using liquid chromatography/electrospray ionization tandem mass spectrometry and liquid chromatography/quadrupole time-of-flight mass
Topics: Adamantane; Cannabinoids; Chromatography, Liquid; Drug Contamination; Indazoles; Limit of Detection; Psychotropic Drugs; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2021 |
Rapid detection of synthetic cannabinoid receptor agonists impregnated into paper by attenuated total reflectance Fourier transform infrared spectroscopy.
Topics: Adamantane; Cannabinoid Receptor Agonists; Indazoles; Spectroscopy, Fourier Transform Infrared | 2023 |