adamantane has been researched along with glyburide in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (25.00) | 18.2507 |
| 2000's | 7 (25.00) | 29.6817 |
| 2010's | 14 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kadowitz, PJ; McMahon, TJ; Minkes, RK; Santiago, JA | 1 |
| De Weille, J; Fosset, M; Guillemare, E; Honore, E; Lazdunski, M; Meisheri, K | 1 |
| Khan, SA; Meisheri, KD; Ohrnberger, CE | 1 |
| Champion, HC; Cheng, DY; DeWitt, BJ; Kandowitz, PJ; Marrone, JR; McMahon, TJ | 1 |
| Huang, DY; Osswald, H; Vallon, V | 2 |
| Fujita, T; Hayashi, I; Inamura, N; Kumagai, Y; Majima, M | 2 |
| Ikeda, S; Kyotani, S; Min, KY; Mori, H; Nagaya, N; Nakanishi, N; Ninomiya, I; Oya, H; Shimouchi, A; Shirai, M | 1 |
| Ito, Y; Naito, S; Teramoto, N; Tomoda, T; Yunoki, T | 1 |
| Al Abed, A; Brock, JA; Tan, JH | 1 |
| El-Ouaghlidi, A; Foley, J; Holmes, D; Holst, JJ; Nauck, MA; Rehring, E; Schweizer, A | 1 |
| Jiang, B; Wang, R; Wu, L | 1 |
| Balez, S; Bullock, J; Dole, WP; He, YL; Jarugula, V; Ligueros-Saylan, M; Riviere, GJ; Schwartz, S; Serra, D; Wang, Y | 1 |
| Boulton, DW; Brenner, E; Handschuh del Corral, M; Komoroski, B; Kornhauser, D; Li, L; Patel, CG; Vachharajani, N | 1 |
| Chacra, AR; Chen, R; List, J; Ravichandran, S; Tan, GH | 1 |
| Allen, E; Chen, R; Donovan, M; Fleming, D; Karyekar, C; Ravichandran, S | 1 |
| Chang, SW; Chen, YZ; Fang, SY; Hsu, CY; Huang, CC; Lam, CF; Liu, YC; Roan, JN; Tsai, YC | 1 |
| Inoue, T; Murai, M; Ochiai, T; Ra, C; Suzuki, Y; Suzuki-Karasaki, M | 1 |
| Allen, E; Fleming, D; Frederich, R; Karyekar, CS; Ravichandran, S | 1 |
| Allen, E; Bryzinski, B; Cook, W; Frederich, R; Slater, J | 1 |
| Frederich, R; Karyekar, CS; Ravichandran, S | 1 |
| Casali, KR; Fofonka, A; Ribeiro, JP; Schaan, BD | 1 |
| Inai, T; Node, K; Takahara, K; Teramoto, N; Yamamoto, T | 1 |
| Hayami, N; Iwasaki, YK; Murakawa, Y; Sekiguchi, A; Yamashita, T | 1 |
| Bhatt, DL; Braunwald, E; Cahn, A; Hirshberg, B; Im, K; Iqbal, N; Kanevsky, E; Leibowitz, G; Mosenzon, O; Raz, I; Rozenberg, A; Scirica, BM; Sjostrand, M; Stahre, C; Yanuv, I | 1 |
| Berlanda, G; Bock, PM; Casali, KR; da Rosa, FM; da Silveira, AD; Fofonka, A; Schaan, BD | 1 |
1 review(s) available for adamantane and glyburide
| Article | Year |
|---|---|
Clinically relevant reductions in HbA1c without hypoglycaemia: results across four studies of saxagliptin.
Topics: Adamantane; Area Under Curve; Controlled Clinical Trials as Topic; Diabetes Mellitus, Type 2; Dipeptides; Drug Therapy, Combination; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemia; Hypoglycemic Agents; Metformin; Treatment Outcome | 2013 |
10 trial(s) available for adamantane and glyburide
| Article | Year |
|---|---|
The dipeptidyl peptidase 4 inhibitor vildagliptin does not accentuate glibenclamide-induced hypoglycemia but reduces glucose-induced glucagon-like peptide 1 and gastric inhibitory polypeptide secretion.
Topics: Adamantane; Adult; Algorithms; C-Peptide; Dipeptidyl-Peptidase IV Inhibitors; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Gastric Emptying; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose; Glyburide; Humans; Hydrocortisone; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Nitriles; Pyrrolidines; Vildagliptin | 2007 |
Evaluation of pharmacokinetic and pharmacodynamic interaction between the dipeptidyl peptidase IV inhibitor vildagliptin, glyburide and pioglitazone in patients with Type 2 diabetes.
Topics: Adamantane; Adult; Aged; Area Under Curve; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Drug Interactions; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Nitriles; Pioglitazone; Pyrrolidines; Thiazolidinediones; Vildagliptin | 2008 |
Saxagliptin, a potent, selective inhibitor of DPP-4, does not alter the pharmacokinetics of three oral antidiabetic drugs (metformin, glyburide or pioglitazone) in healthy subjects.
Topics: Adamantane; Adolescent; Adult; Cross-Over Studies; Diabetes Mellitus, Type 2; Dipeptides; Dipeptidyl-Peptidase IV Inhibitors; Drug Interactions; Drug Therapy, Combination; Female; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Pioglitazone; Thiazolidinediones; Young Adult | 2011 |
Safety and efficacy of saxagliptin in combination with submaximal sulphonylurea versus up-titrated sulphonylurea over 76 weeks.
Topics: Adamantane; Aged; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptides; Dipeptidyl-Peptidase IV Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemia; Hypoglycemic Agents; Kaplan-Meier Estimate; Male; Middle Aged; Time Factors; Treatment Outcome | 2011 |
Efficacy and safety of saxagliptin combination therapy in US patients with type 2 diabetes.
Topics: Adamantane; Adolescent; Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptides; Dipeptidyl-Peptidase IV Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Thiazolidinediones; United States; Young Adult | 2011 |
Tolerability and efficacy of glycemic control with saxagliptin in older patients (aged ≥ 65 years) with inadequately controlled type 2 diabetes mellitus.
Topics: Adamantane; Aged; Aged, 80 and over; Analysis of Variance; Area Under Curve; Diabetes Mellitus, Type 2; Dipeptides; Double-Blind Method; Drug Therapy, Combination; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Incretins; Male; Metformin; Thiazolidinediones; Treatment Outcome | 2013 |
Saxagliptin efficacy and safety in patients with type 2 diabetes mellitus and cardiovascular disease history or cardiovascular risk factors: results of a pooled analysis of phase 3 clinical trials.
Topics: Adamantane; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Dipeptides; Dipeptidyl-Peptidase IV Inhibitors; Drug Therapy, Combination; Glyburide; Humans; Hypoglycemic Agents; Metformin; Risk Factors; Thiazolidinediones | 2013 |
Effects of vildagliptin compared with glibenclamide on glucose variability after a submaximal exercise test in patients with type 2 diabetes: study protocol for a randomized controlled trial, DIABEX VILDA.
Topics: Adamantane; Biomarkers; Blood Glucose; Brazil; Clinical Protocols; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Endothelium, Vascular; Exercise Test; Glyburide; Glycated Hemoglobin; Hemodynamics; Humans; Hypoglycemic Agents; Nitriles; Oxidative Stress; Predictive Value of Tests; Prospective Studies; Pyrrolidines; Research Design; Time Factors; Treatment Outcome; Vildagliptin | 2014 |
Predisposing Factors for Any and Major Hypoglycemia With Saxagliptin Versus Placebo and Overall: Analysis From the SAVOR-TIMI 53 Trial.
Topics: Adamantane; Aged; Body Mass Index; Diabetes Mellitus, Type 2; Dipeptides; Female; Follow-Up Studies; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin, Short-Acting; Male; Middle Aged; Multivariate Analysis; Proportional Hazards Models; Renal Insufficiency; Risk Factors; Sulfonylurea Compounds | 2016 |
Impact of treatment with glibenclamide or vildagliptin on glucose variability after aerobic exercise in type 2 diabetes: A randomized controlled trial.
Topics: Adamantane; Aged; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Exercise; Female; Glucose; Glyburide; Humans; Hypoglycemic Agents; Male; Middle Aged; Nitriles; Pyrrolidines; Vildagliptin | 2018 |
17 other study(ies) available for adamantane and glyburide
| Article | Year |
|---|---|
Role of K+ATP channels and EDRF in reactive hyperemia in the hindquarters vascular bed of cats.
Topics: Adamantane; Adenosine Triphosphate; Animals; Arginine; Cats; Glyburide; Hindlimb; Hyperemia; Ischemia; Morpholines; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Potassium Channels; Pulmonary Circulation; Regional Blood Flow; Vasodilation; Vasodilator Agents | 1995 |
Functional receptors in Xenopus oocytes for U-37883A, a novel ATP-sensitive K+ channel blocker: comparison with rat insulinoma cells.
Topics: Adamantane; Adenosine Triphosphate; Animals; Binding Sites; Female; Glyburide; Insulinoma; Morpholines; Oocytes; Potassium Channels; Rats; Tumor Cells, Cultured; Xenopus laevis | 1994 |
Synergistic effects of glyburide and U-37883A, two structurally different vascular ATP-sensitive potassium channel antagonists.
Topics: Adamantane; Adenosine Triphosphate; Animals; Benzopyrans; Cromakalim; Drug Synergism; Gallopamil; Glyburide; In Vitro Techniques; Ion Channel Gating; Male; Mesenteric Arteries; Minoxidil; Morpholines; Potassium Channels; Pyrroles; Rabbits; Vasodilation | 1993 |
Effects of U-37883A, a vascular selective KATP+ channel antagonist, in the pulmonary and hindlimb circulation.
Topics: Adamantane; Animals; Blood Vessels; Cats; Extremities; Female; Glyburide; Male; Morpholines; Potassium Channel Blockers; Pulmonary Circulation; Vasodilation | 1996 |
Eukaliuric diuresis and natriuresis in response to the KATP channel blocker U37883A: micropuncture studies on the tubular site of action.
Topics: Adamantane; Animals; Diuresis; Diuretics; Furosemide; Glomerular Filtration Rate; Glyburide; Hypoglycemic Agents; Kidney Tubules, Distal; Kidney Tubules, Proximal; Loop of Henle; Morpholines; Natriuresis; Potassium Channels; Punctures; Rats | 1999 |
Early increases in renal kallikrein secretion on administration of potassium or ATP-sensitive potassium channel blockers in rats.
Topics: Adamantane; Adenosine Triphosphate; Animals; Chlorides; Dose-Response Relationship, Drug; Gluconates; Glyburide; In Vitro Techniques; Kallikreins; Kidney; Male; Morpholines; Perfusion; Polyethylene Glycols; Potassium; Potassium Channel Blockers; Potassium Chloride; Rats; Rats, Sprague-Dawley; Sodium; Time Factors; Urination | 1999 |
K+ loading, but not Na+ loading, and blockade of ATP-sensitive K+ channels augment renal kallikrein secretion.
Topics: Adamantane; Animals; ATP-Binding Cassette Transporters; Glyburide; Kallikreins; KATP Channels; Kidney; Male; Morpholines; Potassium; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Rats, Sprague-Dawley; Sodium | 1999 |
Sodium reabsorption in thick ascending limb of Henle's loop: effect of potassium channel blockade in vivo.
Topics: Adamantane; Animals; Barium; Cesium; Charybdotoxin; Dose-Response Relationship, Drug; Glyburide; Loop of Henle; Male; Models, Biological; Morpholines; Potassium; Potassium Channel Blockers; Potassium Channels; Quinine; Rats; Rats, Wistar; Sodium; Verapamil | 2000 |
K(ATP) channels predominantly regulate conduit vessel tone in normoxic cat pulmonary arteries in vivo.
Topics: Adamantane; Adenosine Triphosphate; Animals; Blood Pressure; Cats; Cromakalim; Dose-Response Relationship, Drug; Glyburide; Morpholines; Potassium Channels; Pulmonary Artery; Vasoconstriction; Vasodilator Agents | 2001 |
Multiple actions of U-37883A, an ATP-sensitive K+ channel blocker, on membrane currents in pig urethra.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adamantane; Adenosine Triphosphate; Analysis of Variance; Animals; Barium; Calcium Channel Agonists; Cromakalim; Dose-Response Relationship, Drug; Female; Glyburide; In Vitro Techniques; Membrane Potentials; Morpholines; Muscle Cells; Nitroprusside; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; Swine; Time Factors; Urethra; Vasodilator Agents | 2005 |
Inhibition of KATP channels in the rat tail artery by neurally released noradrenaline acting on postjunctional alpha2-adrenoceptors.
Topics: Adamantane; Adenosine Triphosphate; Animals; Arteries; Calcitonin Gene-Related Peptide; Cromakalim; Dose-Response Relationship, Drug; Electric Impedance; Excitatory Postsynaptic Potentials; Female; Glyburide; In Vitro Techniques; Ion Channel Gating; Morpholines; Muscle, Smooth, Vascular; Norepinephrine; Pinacidil; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Sympathetic Nervous System; Tail; Time Factors | 2007 |
Sulphonylureas induced vasorelaxation of mouse arteries.
Topics: Adamantane; Animals; Arteries; Endothelium, Vascular; Glyburide; In Vitro Techniques; KATP Channels; Male; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Morpholines; Muscle Relaxation; Muscle, Smooth, Vascular; Oxadiazoles; Phenylephrine; Potassium Channel Blockers; Quinoxalines; Sulfonylurea Compounds; Vascular Resistance; Vasoconstrictor Agents | 2007 |
Cardiovascular protection of activating KATP channel during ischemia-reperfusion acidosis.
Topics: Acidosis; Adamantane; Animals; Aorta, Abdominal; Calcium; Dose-Response Relationship, Drug; Glyburide; Hemodynamics; KATP Channels; Morpholines; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tissue Culture Techniques; Vasodilation | 2012 |
Depolarization potentiates TRAIL-induced apoptosis in human melanoma cells: role for ATP-sensitive K+ channels and endoplasmic reticulum stress.
Topics: Adamantane; Antineoplastic Agents; Apoptosis; Caspase 12; Caspase 3; Caspase 7; Endoplasmic Reticulum Stress; Enzyme Activation; Glyburide; Humans; KATP Channels; Melanocytes; Melanoma; Membrane Potential, Mitochondrial; Membrane Potentials; Morpholines; Potassium; Potassium Channel Blockers; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured | 2012 |
Vildagliptin monotherapy. To be avoided, like other DPP-4 inhibitors.
Topics: Adamantane; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Glyburide; Humans; Hypoglycemic Agents; Metformin; Nitriles; Pyrrolidines; Vildagliptin | 2013 |
Molecular analysis of ATP-sensitive K(+) channel subunits expressed in mouse portal vein.
Topics: Adamantane; Animals; Glyburide; Imidazoles; KATP Channels; Male; Mice; Mice, Inbred BALB C; Morpholines; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Patch-Clamp Techniques; Pinacidil; Portal Vein; Real-Time Polymerase Chain Reaction; Sulfonylurea Receptors; Thioamides | 2015 |
No Additional Effect of DPP-4 Inhibitor on Preventing Atrial Fibrosis in Streptozotocin-Induced Diabetic Rat as Compared With Sulfonylurea.
Topics: Adamantane; Animals; Anti-Inflammatory Agents; Atrial Fibrillation; Diabetes Mellitus, Experimental; Dipeptidyl-Peptidase IV Inhibitors; Endomyocardial Fibrosis; Female; Glyburide; Heart Atria; Hypoglycemic Agents; Immunohistochemistry; Inflammation; Nitriles; Pyrrolidines; Rats; Rats, Wistar; Statistics as Topic | 2016 |