Compounds > adamantane
Page last updated: 2024-08-21

adamantane and arterolane

adamantane has been researched along with arterolane in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's6 (75.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Alker, A; Charman, SA; Charman, WN; Chiu, FC; Dong, Y; Hunziker, D; Morizzi, J; Ruf, A; Scheurer, C; Vennerstrom, JL; Wang, X; Wittlin, S; Zhou, L1
Brughera, M; Colombo, P; Craft, JC; Longo, M; Moehrle, J; Vennerstrom, JL; Wittlin, S; Zanoncelli, S1
Anstey, NM; Chalfein, F; Haynes, RK; Kenangalem, E; Marfurt, J; Möhrle, JJ; Piera, KA; Prayoga, P; Price, RN; Sebayang, B; Wabiser, F; Wirjanata, G; Wittlin, S1
Charman, SA; Chiu, FC; Chollet, J; Dong, Y; Katneni, K; Mannila, J; Morizzi, J; Ryan, E; Santo Tomas, J; Scheurer, C; Snyder, C; Steuten, J; Vennerstrom, JL; Wang, X; Wittlin, S1
Iyengar, K; Roepe, PD; Siriwardana, A1
Baumgärtner, F; Blasco, B; Campo, B; Jourdan, J; Mäser, P; Scheurer, C; Wittlin, S1
Charman, SA; Creek, DJ; Giannangelo, C; Stingelin, L; Tilley, L; Yang, T1
Anderson, BM; Charman, SA; Creek, DJ; De Paoli, A; Edgington-Mitchell, LE; Giannangelo, C; Siddiqui, G1

Other Studies

8 other study(ies) available for adamantane and arterolane

ArticleYear
Characterization of the two major CYP450 metabolites of ozonide (1,2,4-trioxolane) OZ277.
    Bioorganic & medicinal chemistry letters, 2008, Mar-01, Volume: 18, Issue:5

    Topics: Adamantane; Antimalarials; Cytochrome P-450 Enzyme System; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Humans; Microsomes, Liver; Molecular Structure; Peroxides; Spiro Compounds

2008
Comparative embryotoxicity of different antimalarial peroxides: in vitro study using the rat whole embryo culture model (WEC).
    Reproductive toxicology (Elmsford, N.Y.), 2010, Volume: 30, Issue:4

    Topics: Adamantane; Animals; Antimalarials; Artemisinins; Branchial Region; Drug Evaluation, Preclinical; Embryo Culture Techniques; Embryo, Mammalian; Embryonic Development; Erythrocytes; Heterocyclic Compounds, 1-Ring; Inhibitory Concentration 50; No-Observed-Adverse-Effect Level; Peroxides; Plasmodium falciparum; Rats; Spiro Compounds; Structure-Activity Relationship; Teratogens; Yolk Sac

2010
Comparative ex vivo activity of novel endoperoxides in multidrug-resistant plasmodium falciparum and P. vivax.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:10

    Topics: Adamantane; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance, Multiple; Heterocyclic Compounds, 1-Ring; Microbial Sensitivity Tests; Peroxides; Plasmodium falciparum; Plasmodium vivax; Quinolines; Spiro Compounds

2012
Comparative antimalarial activities and ADME profiles of ozonides (1,2,4-trioxolanes) OZ277, OZ439, and their 1,2-dioxolane, 1,2,4-trioxane, and 1,2,4,5-tetraoxane isosteres.
    Journal of medicinal chemistry, 2013, Mar-28, Volume: 56, Issue:6

    Topics: Absorption; Adamantane; Animals; Antimalarials; Dioxolanes; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Male; Mice; Peroxides; Plasmodium berghei; Plasmodium falciparum; Spiro Compounds; Structure-Activity Relationship; Tetraoxanes

2013
Endoperoxide Drug Cross-Resistance Patterns for Plasmodium falciparum Exhibiting an Artemisinin Delayed-Clearance Phenotype.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:11

    Topics: Adamantane; Antimalarials; Artemether; Artemisinins; Dose-Response Relationship, Drug; Drug Resistance; Heterocyclic Compounds, 1-Ring; Inactivation, Metabolic; Lethal Dose 50; Microbial Sensitivity Tests; Peroxides; Plasmodium falciparum; Spiro Compounds

2016
In vitro activity of anti-malarial ozonides against an artemisinin-resistant isolate.
    Malaria journal, 2017, 01-25, Volume: 16, Issue:1

    Topics: Adamantane; Antimalarials; Artemisinins; Drug Resistance; Heterocyclic Compounds, 1-Ring; Peroxides; Plasmodium falciparum; Spiro Compounds

2017
Parasite-Mediated Degradation of Synthetic Ozonide Antimalarials Impacts
    Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:3

    Topics: Adamantane; Antimalarials; Erythrocytes; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Humans; Peroxides; Plasmodium falciparum; Spiro Compounds; Trophozoites

2018
System-wide biochemical analysis reveals ozonide antimalarials initially act by disrupting Plasmodium falciparum haemoglobin digestion.
    PLoS pathogens, 2020, Volume: 16, Issue:6

    Topics: Adamantane; Antimalarials; Erythrocytes; Hemoglobins; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Humans; Peroxides; Plasmodium falciparum; Proteomics; Spiro Compounds

2020