acyclovir and fluorophosphate

acyclovir has been researched along with fluorophosphate* in 1 studies

Other Studies

1 other study(ies) available for acyclovir and fluorophosphate

Article	Year
[Synthesis and antiherpes activity of acyclovir phosphoesters]. Bioorganicheskaia khimiia, 1997, Volume: 23, Issue:11 9-(Hydroxyethyloxymethyl)guanine (acyclovir) phosphite and fluorophosphate were synthesized by the reactions of acyclovir with phosphorus trichloride in triethyl phosphate and with fluorophosphoric acid in the presence of 2,4,6-triisopropylbenzenesulfonyl chloride, respectively, and characterized by the data of 1H and 31P NMR and mass spectra. These products selectively inhibit reproduction of the herpes simplex virus type 1 in the Vero cell culture, the phosphite being also substantially active against a herpes virus strain resistant to acyclovir. Topics: Acyclovir; Animals; Antiviral Agents; Chlorides; Chlorocebus aethiops; Drug Resistance; Fluorides; Herpesvirus 1, Human; Organophosphates; Phosphates; Phosphorus Compounds; Vero Cells; Virus Replication	1997

Article

Year

[Synthesis and antiherpes activity of acyclovir phosphoesters].

Bioorganicheskaia khimiia, 1997, Volume: 23, Issue:11

9-(Hydroxyethyloxymethyl)guanine (acyclovir) phosphite and fluorophosphate were synthesized by the reactions of acyclovir with phosphorus trichloride in triethyl phosphate and with fluorophosphoric acid in the presence of 2,4,6-triisopropylbenzenesulfonyl chloride, respectively, and characterized by the data of 1H and 31P NMR and mass spectra. These products selectively inhibit reproduction of the herpes simplex virus type 1 in the Vero cell culture, the phosphite being also substantially active against a herpes virus strain resistant to acyclovir.

Topics: Acyclovir; Animals; Antiviral Agents; Chlorides; Chlorocebus aethiops; Drug Resistance; Fluorides; Herpesvirus 1, Human; Organophosphates; Phosphates; Phosphorus Compounds; Vero Cells; Virus Replication

1997