acth-(4-7)--pro-gly-pro- and beta-casomorphin-7

acth-(4-7)--pro-gly-pro- has been researched along with beta-casomorphin-7* in 4 studies

Reviews

2 review(s) available for acth-(4-7)--pro-gly-pro- and beta-casomorphin-7

ArticleYear
The effects of ante- and postnatal hypoxia on the central nervous system and their correction with peptide hormones.
    Neuroscience and behavioral physiology, 2003, Volume: 33, Issue:6

    Ante- and postnatal hypoxia significantly worsened the postnatal development of animals. The posthypoxic behavioral model included hyperactivity and decreased learning ability, these being typical manifestations of attention deficit disorder. A peptide constellation prevented and significantly improved posthypoxic postnatal development and eliminated the majority of negative behavioral changes.

    Topics: Adrenocorticotropic Hormone; Animals; Brain; Drug Therapy, Combination; Endorphins; Female; Humans; Hypoxia; Neuroprotective Agents; Peptide Fragments; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Rats; Thyrotropin-Releasing Hormone

2003
[Effect of antenatal and postnatal hypoxia on the central nervous system and its correction with peptide hormones].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2002, Volume: 88, Issue:2

    Ante- and postnatal acute hypoxia significantly aggravated the postnatal development. The posthypoxic behaviour patterns included hyperactivity and training ability inhibition typical for the attention deficit syndrome. A preventive injection of peptide constellation significantly improved the posthypoxic postnatal development and abolished the most of the negative modifications of behavioural patterns.

    Topics: Adrenocorticotropic Hormone; Animals; Animals, Newborn; Attention; Behavior, Animal; Brain; Endorphins; Female; Hypoxia; Oxygen; Peptide Fragments; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Thyrotropin-Releasing Hormone

2002

Other Studies

2 other study(ies) available for acth-(4-7)--pro-gly-pro- and beta-casomorphin-7

ArticleYear
Consequences of progestational hypoxia in pregnant rats and its peptide correction (EEG data).
    Bulletin of experimental biology and medicine, 2003, Volume: 135, Issue:6

    We studied immediate and delayed changes in ECG in female albino rats subjected to acute hypobaric hypoxia on days 4-5 of pregnancy and evaluated the possibility of correction of hypoxia-produced disturbances with some peptides. Acute hypoxia lengthened the mean RR interval, increased heart rate variability, and decreased the monotony index. Hypoxia induced considerable changes in the structure of ECG that reflected the development of arrhythmias and conduction disturbances. These changes in ECG persisted during the posthypoxic period. Intranasal administration of heptapeptides Semax and beta-casomorphin-7 to pregnant females promoted recovery from acute hypoxia and normalized ECG in the posthypoxic period.

    Topics: Adrenocorticotropic Hormone; Animals; Atmospheric Pressure; Electrocardiography; Endorphins; Female; Heart Rate; Hypoxia; Myocardium; Peptide Fragments; Pregnancy; Rats

2003
[Dependence of neuropeptide physiological effects on a route of administration].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2001, Volume: 87, Issue:11

    Following intranasal administration, the peptides' effects could remain either the same as following an invasive administration (ACTH4-10) which is important for clinical application, or enhanced and prolonged (demorphin and argynilvasopressin analogue), or modified (beta-casomorphin-7). Techniques of improvement of the peptides' regulatory efficacy through protection against the protease action, are discussed. Peptide protection by introducing D-aminoacid's isomers into its molecule or addition of proline-rich sequences were compared. The latter technique seems to be more effective.

    Topics: Administration, Intranasal; Adrenocorticotropic Hormone; Animals; Arginine Vasopressin; Avoidance Learning; Behavior, Animal; Endorphins; Injections, Intraperitoneal; Male; Neuroprotective Agents; Oligopeptides; Opioid Peptides; Pain Measurement; Peptide Fragments; Rats; Rats, Wistar

2001