acteoside and linarin
acteoside has been researched along with linarin* in 2 studies
Other Studies
2 other study(ies) available for acteoside and linarin
| Article | Year |
|---|---|
Separation of acteoside and linarin from Buddlejae Flos by high-speed countercurrent chromatography and their anti-inflammatory activities.
Buddleja officinalis Maxim., a deciduous, flowering shrub, is used as a traditional Chinese medicine; the bioactivity of B. officinalis is primarily due to flavonoids and phenylethanoid glycosides. In the study, acteoside and linarin were successfully isolated from B. officinalis by high-speed countercurrent chromatography with a two-phase solvent system composed of ethyl acetate: n-butanol: water (5:0.8:5, v/v/v). The purities of acteoside and linarin were determined to be 97.3 and 98.2%, respectively, using one-step high-speed countercurrent chromatography separation. The chemical structures of the two compounds were identified by electrospray ionization-mass spectrometry and nuclear magnetic resonance. After separation, the anti-inflammatory effects of the two compounds were evaluated using lipopolysaccharide-induced human umbilical vein endothelial cells. Acteoside and linarin inhibited the expression of nitric oxide, tumor necrosis factor α and interleukin 1β, which demonstrated that acteoside and linarin possessed anti-inflammatory activity. Topics: Anti-Inflammatory Agents; Cells, Cultured; Countercurrent Distribution; Flowers; Glucosides; Glycosides; Humans; Lipopolysaccharides; Loganiaceae; Medicine, Chinese Traditional; Molecular Structure; Nitric Oxide; Phenols | 2020 |
Photoprotective activity of Buddleja scordioides.
The purpose of this study was to determine the photoprotective properties of the methanolic extract of Buddleja scordioides, as well as verbascoside and linarin which were isolated from this extract, and linarin acetate prepared in the laboratory. The photoprotective effect of substances against UV-B induced cellular death was evaluated by challenge experiments using Escherichia coli. Verbascoside and linarin acetate showed the highest protection. The sun protection factor (SPF) of the methanolic extract, linarin, linarin acetate, and verbascoside was evaluated by guinea pig bioassays. Verbascoside showed the largest SPF measurement. Topics: Animals; Buddleja; Escherichia coli; Female; Glucosides; Glycosides; Guinea Pigs; Male; Molecular Structure; Phenols; Plant Components, Aerial; Sunscreening Agents; Time Factors; Ultraviolet Rays | 2005 |