acteoside has been researched along with catechol* in 1 studies
1 other study(ies) available for acteoside and catechol
Article | Year |
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Inhibition of amyloid β aggregation by acteoside, a phenylethanoid glycoside.
We examined the effects of acteoside (1a), which was isolated from Orobanche minor, and its derivatives on the aggregation of a 42-mer amyloid β protein (Aβ42) in our search for anti-amyloidogenic compounds for Alzheimer's disease (AD) therapy. Acteoside (1a) strongly inhibited the aggregation of Aβ42 in a dose-dependent manner. The structure-activity relationship for acteoside (1a) and related compounds suggests the catechol moiety of phenylethanoid glycosides to be essential for this inhibitory activity. Topics: Alzheimer Disease; Amyloid beta-Peptides; Catechols; Dose-Response Relationship, Drug; Glucosides; Humans; Orobanche; Peptide Fragments; Phenols; Plant Extracts; Structure-Activity Relationship | 2013 |