Compounds > acrylamide
Page last updated: 2024-08-17

acrylamide and glycidamide

acrylamide has been researched along with glycidamide in 164 studies

Research

Studies (164)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's12 (7.32)18.2507
2000's65 (39.63)29.6817
2010's65 (39.63)24.3611
2020's22 (13.41)2.80

Authors

AuthorsStudies
Bergmark, E; Calleman, CJ; Costa, LG; Deng, H; Faustman, EM; Gregotti, C; Manzo, L1
Bergmark, E; Calleman, CJ; Costa, LG1
Friedman, MA; Gulati, AK; Harris, CH; Sickles, DW1
Brusick, DJ; Dearfield, KL; Douglas, GR; Ehling, UH; Moore, MM; Sega, GA1
Abou-Donia, MB; Friedman, MA; Reagan, KE; Wilmarth, KR1
Bergmark, E; Calleman, CJ; Costa, LG; Deng, H1
Calleman, CJ; Costa, LG; Faustman, EM; Schroeder, JL; Segerbäck, D1
Bergmark, E; Calleman, CJ; Costa, LG; Stern, LG1
Abou-Donia, MB; Corcoran, JJ; Friedman, MA; Ibrahim, SM; Lack, L; Lapadula, DM1
Brat, DJ; Brimijoin, S1
Bergmark, E; Calleman, CJ; Costa, LG; He, F1
Cheong, HK; Osterman-Golkar, S; Pérez, HL; Yang, JS1
Adler, ID; Baumgartner, A; Friedman, MA; Gonda, H; Skerhut, M1
Barber, DS; Ehrich, M; Hunt, J; LoPachin, RM1
Andersen, ME; Deskin, R; Gargas, ML; Kirman, CR; Tonner-Navarro, L1
Golding, B; Granath, F; Grawé, J; Henderson, A; Kotova, N; Paulsson, B; Törnqvist, M1
Fennell, TR; Krol, WL; Snyder, RW; Sumner, SC1
Beland, FA; Churchwell, MI; Doerge, DR; Gamboa da Costa, G; Hamilton, LP; Marques, MM; Von Tungeln, LS1
Beland, FA; Churchwell, MI; Doerge, DR; Gamboa da Costa, G; McDaniel, LP; Twaddle, NC2
Besaratinia, A; Pfeifer, GP1
Bridson, WE; Burgess, J; Fennell, TR; Friedman, MA; Snyder, RW; Spicer, R; Sumner, SC1
Churchwell, MI; Doerge, DR; McDaniel, LP; Twaddle, NC; Young, JF2
Favor, J; Shelby, MD1
Golding, BT; Henderson, AP; Paulsson, B; Rannug, A; Törnqvist, M; Warholm, M1
Baum, M; Eisenbrand, G; Fauth, E; Fritzen, S; Herrmann, A; Mertes, P; Merz, K; Rudolphi, M; Zankl, H1
Fueller, F; Marko, D; Puppel, N; Tjaden, Z1
Abramsson-Zetterberg, L; Alexander, J; Husøy, T; Paulsen, JE; Ølstørn, HB1
Angerer, J; Boettcher, MI; Kütting, B; Pischetsrieder, M; Schettgen, T1
Angerer, J; Drexler, H; Kütting, B; Letzel, S; Rossbach, B; Schettgen, T1
Aidoo, A; Bishop, ME; Doerge, DR; Lyn-Cook, LE; Manjanatha, MG; McDaniel, LP; Shelton, SD1
Angerer, J; Boettcher, MI1
Churchwell, MI; Doerge, DR; Fennell, TR; Ghanayem, BI; McDaniel, LP; Snyder, R; Twaddle, NC1
Aschner, M; Friedman, MA; Wu, Q1
Angerer, J; Boettcher, MI; Bolt, HM; Drexler, H1
Glöckner, R; Müller, D; Schömig, E; Taubert, D1
Hayashi, M; Honma, M; Kinae, N; Koizumi, T; Koyama, N; Masuda, S; Matsufuji, H; Sakamoto, H; Sakuraba, M; Takashima, Y; Yamagata, K1
Törnqvist, M1
Baum, M; Bertow, D; Eisenbrand, G; Fauth, E; Fritzen, S; Herrmann, A; Mertes, P; Rudolphi, M; Spormann, T; Zankl, H1
Licea-Perez, H; Meyers, T; Myers, GL; Ospina, M; Vesper, HW1
Fennell, TR; Friedman, MA1
Andersen, ME; Olin, SS; Scimeca, J1
Paulsson, B; Rannug, A; Törnqvist, M; Warholm, M1
Angerer, J; Berkessel, A; Boettcher, MI; Fuhr, U; Harlfinger, S; Jakob, V; Jetter, A; Kinzig-Schippers, M; Klaassen, T; Lazar, A; Pournara, P; Schömig, E; Sörgel, F; Taubert, D; Tomalik-Scharte, D; Weyer, A1
Kurebayashi, H; Ohno, Y1
Kavvadias, D; Riedel, K; Scherer, G; Tricker, AR; Urban, M1
Andry, G; Caillet-Fauquet, P; Chico Galdo, V; Dequanter, D; Friedman, M; Jin, L; Lothaire, P; Massart, C; Van Sande, J; Vanvooren, V1
Dekant, W; Kellert, M; Scholz, K; Völkel, W; Wagner, S1
Churchwell, MI; Doerge, DR; McDaniel, LP; Tareke, E; Twaddle, NC; Young, JF1
Beland, FA; Churchwell, MI; Doerge, DR; Gamboa da Costa, G; Gaspar, JF; Marques, MM; Martins, C; Martins, V; Oliveira, NG; Pingarilho, M; Rueff, J1
Alexander, J; Becher, G; Bjellaas, T; Haugen, M; Lundanes, E; Paulsen, JE; Stølen, LH1
Aureli, F; Aureli, P; Coni, E; Di Pasquale, M; Lucchetti, D1
Doerge, DR; Luecke, RH; Young, JF1
Alexander, J; Becher, G; Bjellaas, T; Frandsen, H; Haugen, M; Lundanes, E; Olesen, PT; Paulsen, JE; Stølen, LH1
Friedman, M; Sickles, DW; Sperry, AO; Testino, A1
Clement, FC; Dip, R; Naegeli, H1
Canlet, C; Chevolleau, S; Debrauwer, L; Jacques, C; Tulliez, J1
Bernert, JT; Ingham, L; Meyers, T; Myers, GL; Ospina, M; Smith, A; Vesper, HW1
Chen, T; Churchwell, MI; Doerge, DR; Guo, L; Hu, J; Mei, N; Moore, MM1
Ginsberg, G; Hattis, D; Russ, A; Sonawane, B; Walker, K1
Frandsen, H; Frederiksen, K; Olesen, PT; Olsen, A; Overvad, K; Tjønneland, A1
Appel, KE; Bernauer, U; Gundert-Remy, U; Klaffke, HS; Palavinskas, R; Settels, E1
Athanassiadis, I; Eriksson, S; Karlsson, P; Paulsson, B; Törnqvist, M; Vikström, AC1
Angerer, J; Hartmann, E; Heudorf, U1
Aylward, LL; Hays, SM1
Granvogl, M; Koehler, P; Latzer, L; Schieberle, P1
Angerer, J; Boettcher, MI; Drexler, H; Fromme, H; Hartmann, EC; Schettgen, T1
Agudo, A; Benetou, V; Bingham, S; Boeing, H; Boutron-Ruault, MC; Bueno-de-Mesquita, HB; Chirlaque, D; Clavel-Chapelon, F; Crowe, F; Drogan, D; Ferrari, P; Hallmans, G; Johansson, I; Kaaks, R; Linseisen, J; Lund, E; Manjer, J; Mattiello, A; Overvad, K; Palli, D; Peeters, PH; Rinaldi, S; Skeie, G; Slimani, N; Strömberg, U; Tjønneland, A; Trichopoulou, A; Vesper, HW; Vineis, P; Wirfält, E1
Bren, U; Galesa, K; Kranjc, A; Mavri, J1
Hellenäs, KE; Rosén, J; Sampson, L; Tocco, P; Törnqvist, M; Vesper, HW; Willett, WC; Wilson, KM1
Fennell, TR; Friedman, M; Haseman, JK; Recio, L; Snyder, RW; Zeiger, E1
Angerer, J; Boettcher, MI; Bolt, HM; Drexler, H; Hartmann, EC1
Annola, K; Keski-Rahkonen, P; Lehtonen, M; Vähäkangas, K1
Beland, FA; Churchwell, MI; Doerge, DR; Gamboa da Costa, G; Heflich, RH; Marques, MM; McGarrity, LJ; Shaddock, JG; Von Tungeln, LS1
Alexander, J; Becher, G; Bjellaas, T; Brunborg, G; Duale, N; Frandsen, H; Haugen, M; Olesen, PT; Paulsen, JE1
Fogliano, V; Hauder, J; Koehler, P; Pernice, R; Somoza, V; Vitaglione, P1
Carson, ML; Gargas, ML; Kirman, CR; Sweeney, LM; Tardiff, RG2
Angerer, J; Fromme, H; Müller, J; Schettgen, T1
Brunborg, G; Hansen, SH; Olsen, AK; Søderlund, EJ1
Caudill, SP; Meyers, T; Myers, GL; Osterloh, JD; Scott, D; Vesper, HW1
Azuma, M; Dobrovolsky, VN; Doerge, DR; Guo, X; Heflich, RH; McDaniel, LP; McGarrity, LJ; Mei, N; Mittelstaedt, RA; Shaddock, JG; Shelton, SD1
Honma, M; Kinae, N; Koyama, N; Masuda, S; Matsuda, T; Oda, Y; Satoh, T; Suzuki, S; Suzuki, T; Yasui, M1
Doerge, DR; Manjanatha, MG; McDaniel, LP; Mei, N; Shelton, SD; Wang, RS1
Barraj, LM; Bi, X; Murphy, MM; Tran, NL1
Hammons, GJ; Lyn-Cook, BD; Lyn-Cook, LE; Starlard-Davenport, A; Tareke, E; Word, B1
Baum, M; Berger, FI; Bertow, D; Eisenbrand, G; Feld, J; Fricker, G; Gerhardt, N; Merz, KH; Richling, E1
Abramsson-Zetterberg, L; Athanassiadis, I; Granath, FN; Naruszewicz, M; Törnqvist, MÅ; Vikström, AC1
Angerer, J; Hartmann, EC; Koch, HM; Latzin, JM; Schindler, BK1
Feng, CH; Lu, CY1
Flynn, NE; Pruser, KN1
Christensen, J; Dragsted, L; Egeberg, R; Frandsen, H; Olesen, PT; Olsen, A; Outzen, M; Overvad, K; Tjønneland, A1
Motwani, HV; Törnqvist, M1
Myöhänen, K; Vähäkangas, K1
Abramsson-Zetterberg, L; Backman, J; Cornelius, M; Jurén, T; Kotova, N; Kronberg, L; Menzel, U; Myöhänen, K; Rydberg, P; Segerbäck, D; Vähäkangas, K1
Knudsen, LE; Nielsen, JK; Pedersen, M; Rydberg, P; Segerbäck, D; Törnqvist, M; Vikström, AC; von Stedingk, H1
Brevik, A; Brunborg, G; Duale, N; Kubista, M; Lindeman, B; Olsen, AK; Rusnakova, V; Slagsvold, HH; Storeng, R1
Blade, LM; Clark, JC; Marlow, D; Moorman, WJ; Reutman, SS; Schrader, SM; Shaw, PB; Vesper, H1
Baum, M; Berger, F; Böhm, N; Eisenbrand, G; Feld, J; Lampen, A; Merz, KH; Reemtsma, T; Richling, E; Scherbl, D; Skipper, PL; Tannenbaum, SR; Watzek, N1
Beland, FA; Doerge, DR; Gamboa da Costa, G; Koturbash, I; Matilde Marques, M; Pogribny, IP; Von Tungeln, LS; Witt, WM1
Christensen, J; Frandsen, H; Halkjær, J; Olesen, PT; Olsen, A; Outzen, M; Overvad, K1
Aidoo, A; Ali, AA; Branham, WS; Desai, VG; Fuscoe, JC; Lee, T; Manjanatha, MG; Moland, CL1
de Lima, JP; Fernandes, AS; Gaspar, JF; Martins, C; Oliveira, NG; Pingarilho, M; Rueff, J1
Chen, MF; Chen, ML; Chiang, SY; Huang, YF; Liou, SH; Uang, SN; Wu, KY1
Agramunt, S; Alexander, J; Botsivali, M; Brunborg, G; Chatzi, L; Fleming, S; Fthenou, E; Granum, B; Gutzkow, KB; Hardie, LJ; Kleinjans, JC; Knudsen, LE; Kogevinas, M; Kyrtopoulos, SA; Mendez, MA; Merlo, DF; Nielsen, JK; Pedersen, M; Rydberg, P; Segerbäck, D; Sunyer, J; Törnqvist, M; von Stedingk, H; Wright, J1
Barrett, JR1
Broll, H; Ehlers, A; Hummel, M; Lampen, A; Lenze, D; Zagon, J1
de Lima, JP; Fernandes, AS; Gaspar, JF; Gomes, BC; Labilloy, A; Martins, C; Martins, V; Oliveira, NG; Pingarilho, M; Rueff, J1
Poole, EM; Rosner, BA; Terry, KL; Tworoger, SS; Vesper, HW; Willett, WC; Wilson, KM; Xie, J1
Baum, M; Eisenbrand, G; Habermeyer, M; Hengstler, JG; Richling, E; Scherbl, D; Schug, M; Watzek, N1
Frame, T; Pfeiffer, CM; Sternberg, MR; Vesper, HW1
Chen, H; Cui, B; Kai, G; Liu, Y; Ran, R; Shi, J; Xu, Y1
Katen, AL; Nixon, B; Nixon, BJ; Roman, SD; Schjenken, JE; Stanger, SJ1
Choi, JH; Jeong, SW; Joo, SH; Kim, KB; Kim, TH; Seo, WS; Shin, BS; Shin, JC; Shin, S; Weon, KY1
Abramsson-Zetterberg, L; Bergman, R; Frostne, C; Grawé, J; Haghdoost, S; Jenssen, D; Kotova, N; Paulsson, B; Segerbäck, D; Tareke, E; Törnqvist, M1
Doerge, DR; Guo, LW; Manjanatha, MG; Shelton, SD1
Chiang, SY; Huang, SL; Long, TY; Luo, YS; Shen, LC; Wu, KY1
Katen, AL; Roman, SD1
Bell, S; Bull, P; Cain, M; Cocker, J; Jones, K; Sams, C; Warren, N1
Beuscart, JB; Boulanger, E; Desreumaux, P; Grossin, N; Lorenzi, R; Maladry, F; Nevière, R; Puisieux, F; Sellier, C; Tessier, FJ1
Fennell, TR; Friedman, M; Hansen, B; Snyder, R1
Baglietto, L; Barricarte, A; Boeing, H; Boutron-Ruault, MC; Bueno-de-Mesquita, HB; Chirlaque, MD; Duell, EJ; Ferrari, P; Fiano, V; Freisling, H; Galassom, R; Gunter, MJ; Idahl, A; Katzke, VA; Khaw, KT; Lagiou, P; Larrañaga, N; Lujan-Barroso, L; Lundin, E; Merritt, MA; Mesrine, S; Molina-Portillo, E; Naska, A; Obón-Santacana, M; Onland-Moret, NC; Palli, D; Peeters, PH; Quirós, JR; Riboli, E; Sieri, S; Travis, RC; Trichopoulou, A; Tumino, R; Turzanski-Fortner, R; Vesper, H; Wareham, N; Weiderpass, E1
Chen, F; Hu, X; Li, D; Liu, Y; Wang, P1
Ardanaz, E; Baglietto, L; Boeing, H; Boutron-Ruault, MC; Bueno-de-Mesquita, HB; Castaño, JM; Chamosa, S; Duell, EJ; Ferrari, P; Fortner, RT; Freisling, H; Gunter, MJ; Idahl, A; Khaw, KT; Klinaki, E; Lujan-Barroso, L; Lundin, E; Mattiello, A; Menéndez, V; Merritt, MA; Obón-Santacana, M; Onland-Moret, NC; Ose, J; Papatesta, EM; Peeters, PH; Riboli, E; Sacerdote, C; Saieva, C; Sánchez-Cantalejo, E; Severi, G; Tagliabue, G; Travis, RC; Trichopoulou, A; Tumino, R; Vesper, HW; Wareham, N; Weiderpass, E1
Ardanaz, E; Bergdahl, IA; Boeing, H; Boutron-Ruault, MC; Bueno-de-Mesquita, HB; Cadeau, C; Castaño, JMH; Chamosa, S; De Magistris, MS; Duell, EJ; Fagherazzi, G; Fortner, RT; Freisling, H; Grioni, S; Kaaks, R; Key, T; Khaw, KT; Lagiou, P; Lujan-Barroso, L; Molina-Montes, E; Naska, A; Obón-Santacana, M; Palli, D; Peeters, PH; Ramón Quirós, J; Riboli, E; Trichopoulou, A; Tumino, R; Vesper, H; Vineis, P; Wareham, N; Wennberg, M1
Granvogl, M; Thürer, A1
Li, HF; Manjanatha, MG; Mei, N; Shelton, SD; Townsend, TA1
Aydin, Y; Erkan, M; Yildizbayrak, N; Yilmaz, BO1
Aras, D; Cakar, Z; Can, A; Cinar, O; Ozkavukcu, S1
Bai, R; Cao, W; Chen, G; Guo, J; Lv, N; Xu, C; Yu, D1
Duke, TJ; Marsh, GM; Ruestow, PS1
Jia, W; Ren, Y; Wang, Q; Wu, Y; Zhang, G; Zhang, Y1
Brunborg, G; Gützkow, KB; Hansen, SH; Kronberg, L; Olsen, AK; Pawlowicz, AJ1
Frostne, C; Motwani, HV; Törnqvist, M1
Bai, S; Bai, W; Jiang, X; Jiao, R; Li, M; Ou, S; Sun, J; Tian, L; Zou, F1
Chen, D; Liu, H; Wang, E; Yan, H; Ye, H; Yuan, Y1
Frame, T; Tse, C; Vesper, HW; Yang, M1
Bonotti, A; Carlsson, H; Cipollini, M; Cristaudo, A; Elisei, R; Foddis, R; Gemignani, F; Landi, S; Pellè, L; Romei, C; Törnqvist, M1
David, RM; Gooderham, NJ1
Chen, F; Ji, J; Ji, R; Wang, P1
Behrens, KA; Jania, LA; Koller, BH; Macdonald, JM; Moy, SS; Nguyen, M; Snouwaert, JN; Tikunov, AP1
Cheng, J; Jia, W; Ren, Y; Wang, Q; Zhang, Y; Zhu, L1
Chu, PL; Lin, CY; Liu, HS; Wang, C1
Chen, X; Cheng, J; Han, J; Jia, W; Wang, Q; Zeng, W; Zhang, Y; Zhao, Q1
Arlt, VM; Duffy, V; Gamboa da Costa, G; Hölzl-Armstrong, L; Kucab, JE; Loutkotová, L; Luijten, M; Moody, S; Phillips, DH; Stratton, MR; Zwart, EP1
Lee, C; Lee, YJ; Sim, KH; Triningsih, D; Yang, JH1
Gong, D; Liao, S; Qiu, H; Yin, G1
Cheang, I; Li, X; Liao, S; Lu, X; Yao, W; Zhang, H; Zhou, Y; Zhu, Q; Zhu, X1
Gyselaers, W; Hogervorst, J; Madhloum, N; Nawrot, T; Vesper, HW1
Chen, WL; Cheng, YW; Hung, CC; Kao, TW1
Chiang, SY; Long, TY; Luo, YS; Wu, KY1
Cartus, A; Hemgesberg, M; Schrenk, D; Stegmüller, S1
Britton, RG; Emms, V; Farmer, PB; Grant, D; Jones, DJL; Maxwell, C; Mina, A; Ng, LL; Quinn, P; Schumacher, S; Singh, R1
Chen, X; Jia, W; Jiang, J; Li, Y; Wang, Q; Zhang, Y; Zhu, L1
Chen, X; Jia, W; Jiao, J; Wan, X; Wang, A; Wang, L; Yao, W; Zhang, Y1
Antunes, AMM; Charneira, C; Gouveia-Fernandes, S; Nunes, C; Nunes, J; Rodrigues, A; Serpa, J1
Jia, W; Jiao, J; Liu, X; Wan, X; Xu, C; Zhang, L; Zhang, Y; Zhu, F; Zhuang, P1
Alm, IM; Andersen, JM; Dirven, H; Duale, N; Holme, JA; Lauvås, AJ; Lislien, M; Macko, P; Myhre, O; Paulsen, RE; Pistollato, F; Skarpen, E; Sørensen, V1
Wang, SL; Xia, R; Xu, J; Yang, L; Yu, Y; Zhang, D1
Inoue, M; Ishihara, J; Iwasaki, M; Kitamura, T; Kito, K; Kotemori, A; Matsuda, T; Matsui, Y; Nakadate, M; Narii, N; Sawada, N; Sobue, T; Tsugane, S; Yamaji, T; Zha, L1
Li, X; Lu, Y; Wang, YX; Zhao, FC; Zhou, SJ1
Buckley, JP; Martínez Steele, E; Monteiro, CA1
Akesson, A; Appenzeller, B; Barbone, F; Coscollà, C; F Fernández, S; Federica, L; Gilles, L; Göen, T; Govarts, E; Halldorsson, TI; Haug, LS; Kolossa-Gehring, M; Leander, K; Mariuz, M; Martin, LR; Moshammer, H; Murawski, A; Namorado, S; Nübler, S; Ólafsdóttir, K; Pardo, O; Poteser, M; Rambaud, L; Riou, M; Rosolen, V; Rüther, M; Schäfer, M; Schettgen, T; Schmidt, P; Schoeters, G; Sepai, O; Thomsen, C; Van Nieuwenhuyse, A; Vogel, N; Weber, T; Zarrabi, KHA1

Reviews

9 review(s) available for acrylamide and glycidamide

ArticleYear
Acrylamide: a review of its genotoxicity and an assessment of heritable genetic risk.
    Mutation research, 1995, Volume: 330, Issue:1-2

    Topics: Acrylamide; Acrylamides; Animals; Chromosome Aberrations; Dose-Response Relationship, Drug; Epoxy Compounds; Female; Germ-Line Mutation; Humans; Male; Mutagenicity Tests; Mutagens; Occupational Exposure; Risk Assessment; Species Specificity; Spermatozoa; Water Pollutants

1995
Transmitted mutational events induced in mouse germ cells following acrylamide or glycidamide exposure.
    Mutation research, 2005, Feb-07, Volume: 580, Issue:1-2

    Topics: Acrylamide; Animals; Epoxy Compounds; Germ-Line Mutation; Male; Mice; Mutagenicity Tests; Mutagens; Spermatozoa

2005
Acrylamide in food: the discovery and its implications: a historical perspective.
    Advances in experimental medicine and biology, 2005, Volume: 561

    Topics: Acrylamide; Epoxy Compounds; Food Analysis; Food Contamination; Food Handling; Food Industry; Hemoglobins; Humans; Models, Chemical; Neoplasms; Occupational Exposure

2005
Kinetic and mechanistic data needs for a human phsiologically based pharmacokinetic (PBPK) model for acrylamide: pharmacokinetic model for acrylamide.
    Advances in experimental medicine and biology, 2005, Volume: 561

    Topics: Acrylamide; Animals; Area Under Curve; DNA Adducts; Epoxy Compounds; Humans; Kinetics; Models, Chemical; Models, Statistical; Oxygen; Rats; Research Design; Risk Assessment; Tissue Distribution

2005
Acrylamide in health and disease.
    Frontiers in bioscience (Scholar edition), 2011, 01-01, Volume: 3, Issue:1

    Topics: Acrylamide; Animals; Asparagine; Axons; Environmental Exposure; Epoxy Compounds; Exocytosis; Food Analysis; Humans; Male; Mutagens; Neurotoxins; Nitric Oxide; Spermatozoa; Tobacco Smoke Pollution

2011
Foetal exposure to food and environmental carcinogens in human beings.
    Basic & clinical pharmacology & toxicology, 2012, Volume: 110, Issue:2

    Topics: Acrylamide; Carcinogens, Environmental; Dimethylnitrosamine; DNA Damage; Epoxy Compounds; Female; Fetus; Food Contamination; Humans; Maternal Exposure; Placenta; Pregnancy; Xenobiotics

2012
Risk assessment, formation, and mitigation of dietary acrylamide: current status and future prospects.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2014, Volume: 69

    Topics: Acrylamide; Animals; Asparagine; Biomarkers; Carcinogens; Drinking Water; Environmental Exposure; Epoxy Compounds; Food Safety; Humans; Mutagenicity Tests; Reproduction; Risk Assessment

2014
The genetic consequences of paternal acrylamide exposure and potential for amelioration.
    Mutation research, 2015, Volume: 777

    Topics: Acrylamide; Animals; Carcinogenesis; Carcinogens; Cytochrome P-450 CYP2E1; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Epoxy Compounds; Humans; Male; Mice; Paternal Exposure; Rats; Reproduction; Spermatocytes; Spermatogenesis

2015
Metabolism of Acrylamide: Interindividual and Interspecies Differences as Well as the Application as Biomarkers.
    Current drug metabolism, 2016, Volume: 17, Issue:4

    Topics: Acetylcysteine; Acrylamide; Animals; Biomarkers; Carcinogens; Cytochrome P-450 CYP2E1; DNA Damage; Epoxy Compounds; Food Safety; Glutathione; Glutathione Transferase; Hemoglobins; Humans; Mice; Rats; Risk Assessment; Species Specificity

2016

Other Studies

155 other study(ies) available for acrylamide and glycidamide

ArticleYear
Comparative studies on the neuro- and reproductive toxicity of acrylamide and its epoxide metabolite glycidamide in the rat.
    Neurotoxicology, 1992,Spring, Volume: 13, Issue:1

    Topics: Acrylamide; Acrylamides; Animals; Epoxy Compounds; Male; Nervous System; Rats; Rats, Inbred Strains; Reproduction

1992
Formation of hemoglobin adducts of acrylamide and its epoxide metabolite glycidamide in the rat.
    Toxicology and applied pharmacology, 1991, Volume: 111, Issue:2

    Topics: Acrylamide; Acrylamides; Animals; Cysteine; Epoxy Compounds; Gas Chromatography-Mass Spectrometry; Hemoglobins; Kinetics; Male; Rats; Rats, Inbred Strains

1991
Toxic neurofilamentous axonopathies and fast axonal transport. V. Reduced bidirectional vesicle transport in cultured neurons by acrylamide and glycidamide.
    Journal of toxicology and environmental health, 1994, Volume: 42, Issue:3

    Topics: Acrylamide; Acrylamides; Analysis of Variance; Animals; Axonal Transport; Cells, Cultured; Dose-Response Relationship, Drug; Epoxy Compounds; Rats; Rats, Sprague-Dawley; Time Factors

1994
In vitro calcium and calmodulin-dependent kinase-mediated phosphorylation of rat brain and spinal cord neurofilament proteins is increased by glycidamide administration.
    Brain research, 1995, Feb-06, Volume: 671, Issue:1

    Topics: Acrylamide; Acrylamides; Animals; Brain; Brain Chemistry; Calcium-Calmodulin-Dependent Protein Kinases; Epoxy Compounds; Immunoassay; In Vitro Techniques; Male; Neurofilament Proteins; Neurotoxins; Phosphorylation; Rats; Rats, Sprague-Dawley; Spinal Cord

1995
Evaluation of the neurotoxicity of glycidamide, an epoxide metabolite of acrylamide: behavioral, neurochemical and morphological studies.
    Toxicology, 1995, Apr-12, Volume: 98, Issue:1-3

    Topics: Acrylamide; Acrylamides; Analysis of Variance; Animals; Behavior, Animal; Body Weight; Epoxy Compounds; Gait; Male; Nervous System; Rats; Rats, Sprague-Dawley

1995
Formation of N-7-(2-carbamoyl-2-hydroxyethyl)guanine in DNA of the mouse and the rat following intraperitoneal administration of [14C]acrylamide.
    Carcinogenesis, 1995, Volume: 16, Issue:5

    Topics: Acrylamide; Acrylamides; Alkylating Agents; Animals; Brain; Carbon Radioisotopes; DNA; Epoxy Compounds; Guanine; Kidney; Liver; Lung; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mice; Mice, Inbred BALB C; Rats; Rats, Sprague-Dawley; Spleen; Testis; Tissue Distribution

1995
A nonlinear dosimetric model for hemoglobin adduct formation by the neurotoxic agent acrylamide and its genotoxic metabolite glycidamide.
    Environmental health perspectives, 1993, Volume: 99

    Topics: Acrylamide; Acrylamides; Animals; Dose-Response Relationship, Drug; Epoxy Compounds; Hemoglobins; Humans; Kinetics; Models, Biological; Mutagens; Neurotoxins; Rats

1993
Neurotoxicity of glycidamide, an acrylamide metabolite, following intraperitoneal injections in rats.
    Journal of toxicology and environmental health, 1993, Volume: 39, Issue:4

    Topics: Acrylamide; Acrylamides; Animals; Body Weight; Brain; Epoxy Compounds; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Spinal Cord

1993
Acrylamide and glycidamide impair neurite outgrowth in differentiating N1E.115 neuroblastoma without disturbing rapid bidirectional transport of organelles observed by video microscopy.
    Journal of neurochemistry, 1993, Volume: 60, Issue:6

    Topics: Acrylamide; Acrylamides; Amides; Animals; Cell Differentiation; Cell Survival; Dose-Response Relationship, Drug; Epoxy Compounds; Kinetics; Mice; Neurites; Neuroblastoma; Organelles; Structure-Activity Relationship; Tumor Cells, Cultured; Video Recording

1993
Determination of hemoglobin adducts in humans occupationally exposed to acrylamide.
    Toxicology and applied pharmacology, 1993, Volume: 120, Issue:1

    Topics: Acrylamide; Acrylamides; Acrylonitrile; Adult; Chromatography, Ion Exchange; Epoxy Compounds; Gas Chromatography-Mass Spectrometry; Hemoglobins; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Theoretical; Molecular Structure; Occupational Exposure

1993
Simultaneous analysis of hemoglobin adducts of acrylamide and glycidamide by gas chromatography-mass spectrometry.
    Analytical biochemistry, 1999, Oct-01, Volume: 274, Issue:1

    Topics: Acrylamide; Epoxy Compounds; Gas Chromatography-Mass Spectrometry; Globins; Hemoglobins; Humans; Occupational Exposure; Oligopeptides; Protein Binding; Valine

1999
1-Aminobenzotriazole inhibits acrylamide-induced dominant lethal effects in spermatids of male mice.
    Mutagenesis, 2000, Volume: 15, Issue:2

    Topics: Acrylamide; Animals; Antimutagenic Agents; Epoxy Compounds; Female; Fertility; Genes, Dominant; Genes, Lethal; Male; Mice; Mutagens; Sperm Motility; Spermatids; Triazoles

2000
Determination of acrylamide and glycidamide in rat plasma by reversed-phase high performance liquid chromatography.
    Journal of chromatography. B, Biomedical sciences and applications, 2001, Jul-15, Volume: 758, Issue:2

    Topics: Acrylamide; Animals; Chromatography, High Pressure Liquid; Epoxy Compounds; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet

2001
A physiologically based pharmacokinetic model for acrylamide and its metabolite, glycidamide, in the rat.
    Journal of toxicology and environmental health. Part A, 2003, Feb-14, Volume: 66, Issue:3

    Topics: Acrylamide; Animals; Carcinogens; Cytochrome P-450 Enzyme System; Epoxy Compounds; Models, Biological; Rats; Sensitivity and Specificity; Tissue Distribution

2003
Induction of micronuclei in mouse and rat by glycidamide, genotoxic metabolite of acrylamide.
    Mutation research, 2003, Feb-05, Volume: 535, Issue:1

    Topics: Acrylamide; Animals; Dose-Response Relationship, Drug; Epoxy Compounds; Erythrocytes; Hemoglobins; Male; Mice; Mice, Inbred CBA; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagens; Rats; Rats, Sprague-Dawley

2003
Comparison of the hemoglobin adducts formed by administration of N-methylolacrylamide and acrylamide to rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 2003, Volume: 71, Issue:2

    Topics: Acrylamide; Acrylamides; Administration, Oral; Animals; Chromatography, Liquid; Epoxy Compounds; Hemoglobins; Male; Mass Spectrometry; Rats; Rats, Inbred F344; Valine

2003
DNA adduct formation from acrylamide via conversion to glycidamide in adult and neonatal mice.
    Chemical research in toxicology, 2003, Volume: 16, Issue:10

    Topics: Acrylamide; Aging; Animals; Chromatography, Liquid; DNA Adducts; Dose-Response Relationship, Drug; Epoxy Compounds; Male; Mass Spectrometry; Mice; Molecular Structure; Nucleosides; Reproducibility of Results; Salmon; Testis

2003
Determination of acrylamide and glycidamide serum toxicokinetics in B6C3F1 mice using LC-ES/MS/MS.
    Cancer letters, 2004, Apr-15, Volume: 207, Issue:1

    Topics: Acrylamide; Administration, Oral; Animals; Chromatography, Liquid; Epoxy Compounds; Kinetics; Mice; Models, Chemical; Mutagens; Oxygen; Rats; Spectrometry, Mass, Electrospray Ionization; Time Factors

2004
Genotoxicity of acrylamide and glycidamide.
    Journal of the National Cancer Institute, 2004, Jul-07, Volume: 96, Issue:13

    Topics: Acrylamide; Adenine; Animals; Cell Culture Techniques; Cytosine; DNA Adducts; Dose-Response Relationship, Drug; Epoxy Compounds; Fibroblasts; Guanine; Humans; Mice; Mutagens; Mutation; Polymerase Chain Reaction; Respiratory Mucosa; Thymine; Transferases

2004
Metabolism and hemoglobin adduct formation of acrylamide in humans.
    Toxicological sciences : an official journal of the Society of Toxicology, 2005, Volume: 85, Issue:1

    Topics: Acrylamide; Administration, Cutaneous; Administration, Oral; Adult; Aged; Animals; Carbon Isotopes; Dose-Response Relationship, Drug; Epoxy Compounds; Hemoglobins; Humans; Inactivation, Metabolic; Linear Models; Magnetic Resonance Spectroscopy; Male; Middle Aged; Rats; Rats, Inbred F344

2005
Toxicokinetics of acrylamide and glycidamide in B6C3F1 mice.
    Toxicology and applied pharmacology, 2005, Feb-01, Volume: 202, Issue:3

    Topics: Acrylamide; Administration, Oral; Animals; Biological Availability; Carcinogens; DNA Adducts; Epoxy Compounds; Female; Injections, Intravenous; Liver; Male; Mice; Time Factors; Tissue Distribution

2005
In vitro studies of the influence of glutathione transferases and epoxide hydrolase on the detoxification of acrylamide and glycidamide in blood.
    Mutation research, 2005, Feb-07, Volume: 580, Issue:1-2

    Topics: Acrylamide; Epoxide Hydrolases; Epoxy Compounds; Female; Genotype; Glutathione Transferase; Hemoglobins; Humans; In Vitro Techniques; Inactivation, Metabolic; Male; Polymorphism, Genetic

2005
Acrylamide and glycidamide: genotoxic effects in V79-cells and human blood.
    Mutation research, 2005, Feb-07, Volume: 580, Issue:1-2

    Topics: Acrylamide; Animals; Cell Line; Cell Survival; Comet Assay; Cricetinae; Cricetulus; DNA Damage; Dose-Response Relationship, Drug; Epoxy Compounds; Humans; Lymphocytes; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagenicity Tests; Mutagens

2005
DNA strand breaking capacity of acrylamide and glycidamide in mammalian cells.
    Mutation research, 2005, Feb-07, Volume: 580, Issue:1-2

    Topics: Acrylamide; Animals; Blotting, Western; Caco-2 Cells; Cell Culture Techniques; Cell Line; Cell Survival; Comet Assay; Cricetinae; Cricetulus; Cytochrome P-450 CYP2E1; DNA Damage; Dose-Response Relationship, Drug; Epoxy Compounds; Glutathione; Hepatocytes; Humans; Mutagens; Rats; Time Factors

2005
Adenomatous polyposis coli influences micronuclei induction by PhIP and acrylamide in mouse erythrocytes.
    Mutation research, 2005, Feb-07, Volume: 580, Issue:1-2

    Topics: Acrylamide; Adenomatous Polyposis Coli; Adenomatous Polyposis Coli Protein; Animals; Colchicine; Cytarabine; DNA Adducts; Epoxy Compounds; Erythrocytes; Female; Flow Cytometry; Hydroxyurea; Imidazoles; Injections, Subcutaneous; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagens

2005
DNA adducts derived from administration of acrylamide and glycidamide to mice and rats.
    Mutation research, 2005, Feb-07, Volume: 580, Issue:1-2

    Topics: Acrylamide; Adenine; Administration, Oral; Animals; DNA Adducts; Epoxy Compounds; Female; Guanine; Injections, Intraperitoneal; Male; Mice; Mice, Inbred Strains; Mutagens; Rats; Rats, Inbred F344; Tissue Distribution

2005
Mercapturic acids of acrylamide and glycidamide as biomarkers of the internal exposure to acrylamide in the general population.
    Mutation research, 2005, Feb-07, Volume: 580, Issue:1-2

    Topics: Acetylcysteine; Acrylamide; Adolescent; Adult; Aged; Biomarkers; Epoxy Compounds; Feeding Behavior; Female; Food Contamination; Gas Chromatography-Mass Spectrometry; Germany; Hemoglobins; Humans; Male; Middle Aged; Population Surveillance; Smoking; Surveys and Questionnaires

2005
Determination of haemoglobin adducts of acrylamide and glycidamide in smoking and non-smoking persons of the general population.
    International journal of hygiene and environmental health, 2004, Volume: 207, Issue:6

    Topics: Acrylamide; Acrylamides; Adolescent; Adult; Aged; Biomarkers; Epoxy Compounds; Female; Gas Chromatography-Mass Spectrometry; Germany; Hemoglobins; Humans; Male; Middle Aged; Protein Binding; Smoking; Valine

2004
Genotoxicity of acrylamide and its metabolite glycidamide administered in drinking water to male and female Big Blue mice.
    Environmental and molecular mutagenesis, 2006, Volume: 47, Issue:1

    Topics: Acrylamide; Animals; Epoxy Compounds; Female; Hypoxanthine Phosphoribosyltransferase; Liver; Lymphocytes; Male; Mice; Mice, Transgenic; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagens; Mutation; Transcription Factors; Viral Proteins; Water Supply

2006
Determination of the major mercapturic acids of acrylamide and glycidamide in human urine by LC-ESI-MS/MS.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, Sep-25, Volume: 824, Issue:1-2

    Topics: Acetylcysteine; Acrylamide; Calibration; Chromatography, High Pressure Liquid; Environmental Exposure; Epoxy Compounds; Humans; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization

2005
Role of CYP2E1 in the epoxidation of acrylamide to glycidamide and formation of DNA and hemoglobin adducts.
    Toxicological sciences : an official journal of the Society of Toxicology, 2005, Volume: 88, Issue:2

    Topics: Acrylamide; Animals; Cytochrome P-450 CYP2E1; DNA; DNA Adducts; Epoxy Compounds; Hemoglobins; Liver; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Testis

2005
Effects of acrylamide on primary neonatal rat astrocyte functions.
    Annals of the New York Academy of Sciences, 2005, Volume: 1053

    Topics: Acrylamide; Animals; Animals, Newborn; Astrocytes; Cell Proliferation; Cerebral Cortex; DNA; Dopamine Antagonists; Epoxy Compounds; Leucine; Nerve Tissue Proteins; Proliferating Cell Nuclear Antigen; Rats; Receptors, Dopamine; Receptors, Dopamine D2; Sulpiride; Thymidine

2005
Excretion of mercapturic acids of acrylamide and glycidamide in human urine after single oral administration of deuterium-labelled acrylamide.
    Archives of toxicology, 2006, Volume: 80, Issue:2

    Topics: Acetylcysteine; Acrylamide; Administration, Oral; Deuterium; Epoxy Compounds; Half-Life; Humans; Male; Middle Aged; Reference Standards; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization

2006
Toxicokinetics of acrylamide and glycidamide in Fischer 344 rats.
    Toxicology and applied pharmacology, 2005, Nov-01, Volume: 208, Issue:3

    Topics: Acrylamide; Animals; Area Under Curve; Chromatography, Liquid; Diet; DNA Adducts; Drug Administration Schedule; Epoxy Compounds; Female; Half-Life; Injections, Intravenous; Intubation, Gastrointestinal; Male; Mice; Pharmacokinetics; Rats; Rats, Inbred F344; Serum; Species Specificity; Spectrometry, Mass, Electrospray Ionization; Time Factors; Tissue Distribution

2005
The garlic ingredient diallyl sulfide inhibits cytochrome P450 2E1 dependent bioactivation of acrylamide to glycidamide.
    Toxicology letters, 2006, Jun-20, Volume: 164, Issue:1

    Topics: Acrylamide; Allyl Compounds; Animals; Biotransformation; Cytochrome P-450 CYP2E1; Epoxy Compounds; Garlic; In Vitro Techniques; Liver; Male; Rats; Rats, Wistar; Sulfides

2006
Genotoxicity of acrylamide and glycidamide in human lymphoblastoid TK6 cells.
    Mutation research, 2006, Feb-28, Volume: 603, Issue:2

    Topics: Acrylamide; Animals; Comet Assay; DNA Damage; Epoxy Compounds; Humans; Liver; Loss of Heterozygosity; Lymphocytes; Micronucleus Tests; Mutation; Rats; Thymidine Kinase

2006
Acrylamide and glycidamide: approach towards risk assessment based on biomarker guided dosimetry of genotoxic/mutagenic effects in human blood.
    Advances in experimental medicine and biology, 2005, Volume: 561

    Topics: Acrylamide; Animals; Biomarkers; Cell Line; Cricetinae; Disease Models, Animal; DNA Adducts; DNA Damage; Dose-Response Relationship, Drug; Epoxy Compounds; Humans; Hypoxanthine Phosphoribosyltransferase; Lymphocytes; Micronucleus Tests; Models, Chemical; Mutagens; Risk Assessment; Time Factors

2005
Pilot study on the impact of potato chips consumption on biomarkers of acrylamide exposure.
    Advances in experimental medicine and biology, 2005, Volume: 561

    Topics: Acrylamide; Adolescent; Adult; Biomarkers; Chromatography, Liquid; Epoxy Compounds; Food Analysis; Food Contamination; Hemoglobins; Humans; Mass Spectrometry; Pilot Projects; Reproducibility of Results; Solanum tuberosum; Time Factors

2005
Comparison of acrylamide metabolism in humans and rodents.
    Advances in experimental medicine and biology, 2005, Volume: 561

    Topics: Acrylamide; Animals; Deuterium Oxide; Dose-Response Relationship, Drug; Epoxy Compounds; Glutathione; Humans; Hydrolysis; Magnetic Resonance Spectroscopy; Mice; Models, Chemical; Oxygen; Rats; Species Specificity; Time Factors

2005
In vitro studies of the influence of certain enzymes on the detoxification of acrylamide and glycidamide in blood.
    Advances in experimental medicine and biology, 2005, Volume: 561

    Topics: Acrylamide; Epoxy Compounds; Genotype; Glutathione; Glutathione Transferase; Hemoglobins; Humans; In Vitro Techniques; Inactivation, Metabolic; Polymorphism, Genetic; Risk; Risk Assessment

2005
Toxicokinetics of acrylamide in humans after ingestion of a defined dose in a test meal to improve risk assessment for acrylamide carcinogenicity.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2006, Volume: 15, Issue:2

    Topics: Absorption; Acrylamide; Adult; Animals; Carcinogens; Cooking; Dietary Fats; Epoxy Compounds; Female; Half-Life; Humans; Male; Risk Assessment; Solanum tuberosum; Species Specificity; Time Factors

2006
Metabolism of acrylamide to glycidamide and their cytotoxicity in isolated rat hepatocytes: protective effects of GSH precursors.
    Archives of toxicology, 2006, Volume: 80, Issue:12

    Topics: Acetylcysteine; Acrylamide; Animals; Ascorbic Acid; Biotransformation; Carcinogens; Cell Survival; Cytochrome P-450 CYP2E1; Cytoprotection; Dose-Response Relationship, Drug; Epoxy Compounds; Glutathione; Glutathione Transferase; Hepatocytes; In Vitro Techniques; Kinetics; L-Lactate Dehydrogenase; Male; Methionine; Models, Biological; Protective Agents; Rats; Rats, Sprague-Dawley

2006
Urinary mercapturic acids and a hemoglobin adduct for the dosimetry of acrylamide exposure in smokers and nonsmokers.
    Inhalation toxicology, 2006, Volume: 18, Issue:10

    Topics: Acetylcysteine; Acrylamide; Biomarkers; Chromatography, High Pressure Liquid; Cysteine; Epoxy Compounds; Female; Gas Chromatography-Mass Spectrometry; Hemoglobins; Humans; Male; Nicotiana; Smoking; Valine

2006
Acrylamide, an in vivo thyroid carcinogenic agent, induces DNA damage in rat thyroid cell lines and primary cultures.
    Molecular and cellular endocrinology, 2006, Sep-26, Volume: 257-258

    Topics: Acrylamide; Adenocarcinoma, Follicular; Animals; Carcinogenicity Tests; Cell Culture Techniques; Cell Line; Cells, Cultured; Colforsin; Comet Assay; Cyclic AMP; DNA Damage; Dogs; Dose-Response Relationship, Drug; Epoxy Compounds; Humans; Hydrogen Peroxide; Rats; Sheep; Thyroid Gland; Thyroid Neoplasms; Thyrotropin

2006
Quantitation of mercapturic acids from acrylamide and glycidamide in human urine using a column switching tool with two trap columns and electrospray tandem mass spectrometry.
    Journal of chromatography. A, 2006, Oct-27, Volume: 1131, Issue:1-2

    Topics: Acetylcysteine; Acrylamide; Chromatography, Liquid; Epoxy Compounds; Humans; Molecular Structure; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization

2006
Relationships between biomarkers of exposure and toxicokinetics in Fischer 344 rats and B6C3F1 mice administered single doses of acrylamide and glycidamide and multiple doses of acrylamide.
    Toxicology and applied pharmacology, 2006, Nov-15, Volume: 217, Issue:1

    Topics: Acrylamide; Administration, Oral; Animals; Biomarkers; Chromatography, Liquid; DNA Adducts; Epoxy Compounds; Erythrocytes; Female; Hemoglobins; Humans; Injections, Intravenous; Intubation, Gastrointestinal; Liver; Male; Mice; Microsomes, Liver; Models, Biological; Mutagens; Rats; Rats, Inbred F344; Reproducibility of Results; Risk Assessment; Spectrometry, Mass, Electrospray Ionization; Time Factors

2006
Cytogenetic damage induced by acrylamide and glycidamide in mammalian cells: correlation with specific glycidamide-DNA adducts.
    Toxicological sciences : an official journal of the Society of Toxicology, 2007, Volume: 95, Issue:2

    Topics: Acrylamide; Adenine; Animals; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; DNA Adducts; Dose-Response Relationship, Drug; Epoxy Compounds; Guanine; Molecular Structure; Mutagens; Sister Chromatid Exchange

2007
Urinary acrylamide metabolites as biomarkers for short-term dietary exposure to acrylamide.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2007, Volume: 45, Issue:6

    Topics: Acetylcysteine; Acrylamide; Adult; Biomarkers; Diet; Environmental Exposure; Epoxy Compounds; Female; Humans; Male; Middle Aged; Smoking; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Statistics, Nonparametric

2007
An absorption study of dietary administered acrylamide in swine.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2007, Volume: 45, Issue:7

    Topics: Acrylamide; Administration, Oral; Animals; Biomarkers; Carcinogens, Environmental; Cooking; Diet; Dose-Response Relationship, Drug; Drinking; Epoxy Compounds; Female; Gas Chromatography-Mass Spectrometry; Hemoglobins; Protein Binding; Swine; Valine

2007
Physiologically based pharmacokinetic/pharmacodynamic model for acrylamide and its metabolites in mice, rats, and humans.
    Chemical research in toxicology, 2007, Volume: 20, Issue:3

    Topics: Acrylamide; Algorithms; Animals; Animals, Newborn; Biotransformation; Body Weight; Diet; Drinking; Epoxy Compounds; Female; Humans; Kinetics; Male; Mice; Models, Biological; Rats; Rats, Inbred F344

2007
Comparison of estimated dietary intake of acrylamide with hemoglobin adducts of acrylamide and glycidamide.
    Toxicological sciences : an official journal of the Society of Toxicology, 2007, Volume: 98, Issue:1

    Topics: Acrylamide; Adult; Aging; Alkylation; Calibration; Chromatography, Liquid; Diet; Epoxy Compounds; Female; Hemoglobins; Humans; Linear Models; Male; Middle Aged; Oligopeptides; Reference Standards; Tandem Mass Spectrometry

2007
Acrylamide effects on kinesin-related proteins of the mitotic/meiotic spindle.
    Toxicology and applied pharmacology, 2007, Jul-01, Volume: 222, Issue:1

    Topics: Acrylamide; Amides; Animals; Blotting, Western; Cell Cycle; Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; Epoxy Compounds; Kinesins; Male; Meiosis; Mutagens; Rats; Spindle Apparatus; Testis; Transformation, Bacterial; Tubulin

2007
Expression profile of human cells in culture exposed to glycidamide, a reactive metabolite of the heat-induced food carcinogen acrylamide.
    Toxicology, 2007, Oct-30, Volume: 240, Issue:1-2

    Topics: Acrylamide; Carcinogens, Environmental; Cell Line, Tumor; Epoxy Compounds; Food Contamination; Gene Expression; Gene Expression Profiling; Genes, Reporter; Glutathione; Hot Temperature; Humans; NF-kappa B; Oligonucleotide Array Sequence Analysis

2007
Analysis of hemoglobin adducts of acrylamide and glycidamide by liquid chromatography-electrospray ionization tandem mass spectrometry, as exposure biomarkers in French population.
    Journal of chromatography. A, 2007, Oct-12, Volume: 1167, Issue:2

    Topics: Acrylamide; Adolescent; Adult; Aged; Animals; Biomarkers; Calibration; Chromatography, Liquid; Environmental Exposure; Epoxy Compounds; Female; France; Hemoglobins; Humans; Male; Middle Aged; Molecular Structure; Public Health; Rats; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2007
Assessment of the relation between biomarkers for smoking and biomarkers for acrylamide exposure in humans.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2007, Volume: 16, Issue:11

    Topics: Acrylamide; Adolescent; Adult; Aged; Biomarkers; Cotinine; Epoxy Compounds; Female; Hemoglobins; Humans; Male; Middle Aged; Nicotine; Smoking; Tobacco Smoke Pollution

2007
Genotoxic effects of acrylamide and glycidamide in mouse lymphoma cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2008, Volume: 46, Issue:2

    Topics: Acrylamide; Animals; DNA Adducts; Dose-Response Relationship, Drug; Epoxy Compounds; Loss of Heterozygosity; Lymphoma; Mice; Mutagenicity Tests; Mutagens; Polymerase Chain Reaction; Tumor Cells, Cultured

2008
Approaches to acrylamide physiologically based toxicokinetic modeling for exploring child-adult dosimetry differences.
    Journal of toxicology and environmental health. Part A, 2007, Volume: 70, Issue:24

    Topics: Acrylamide; Adolescent; Adult; Animals; Child; Child, Preschool; Cytochrome P-450 CYP2E1; Dose-Response Relationship, Drug; Epoxide Hydrolases; Epoxy Compounds; Food Contamination; Glutathione; Glutathione Transferase; Humans; Infant; Infant, Newborn; Liver; Models, Biological; Monte Carlo Method; Rats

2007
Acrylamide exposure and incidence of breast cancer among postmenopausal women in the Danish Diet, Cancer and Health Study.
    International journal of cancer, 2008, May-01, Volume: 122, Issue:9

    Topics: Acrylamide; Aged; Biomarkers; Breast Neoplasms; Case-Control Studies; Cohort Studies; Denmark; Environmental Exposure; Epoxy Compounds; Female; Hemoglobins; Humans; Incidence; Medical Record Linkage; Middle Aged; Odds Ratio; Postmenopause; Prospective Studies; Registries; Risk Factors; Smoking

2008
Human CYP2E1 mediates the formation of glycidamide from acrylamide.
    Archives of toxicology, 2008, Volume: 82, Issue:10

    Topics: Acrylamide; Adult; Animals; Biotransformation; Callithrix; Carcinogens; Cell Line; Chlorzoxazone; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Ditiocarb; Enzyme Inhibitors; Epoxy Compounds; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydroxylation; Kinetics; Microsomes, Liver; Middle Aged; Recombinant Proteins; Risk Assessment; Species Specificity; Substrate Specificity; Transfection

2008
Internal doses of acrylamide and glycidamide in mice fed diets with low acrylamide contents.
    Molecular nutrition & food research, 2008, Volume: 52, Issue:8

    Topics: Acrylamide; Animals; Diet; Epoxy Compounds; Hemoglobins; Male; Mice; Mice, Inbred C57BL

2008
Acrylamide in children--exposure assessment via urinary acrylamide metabolites as biomarkers.
    International journal of hygiene and environmental health, 2009, Volume: 212, Issue:2

    Topics: Acetylcysteine; Acrylamide; Biomarkers; Body Burden; Child; Child, Preschool; Cotinine; Creatinine; Environmental Exposure; Epoxy Compounds; Female; Food Contamination; Humans; Male; Solanum tuberosum; Tobacco Smoke Pollution

2009
Biomonitoring Equivalents (BE) dossier for acrylamide (AA) (CAS No. 79-06-1).
    Regulatory toxicology and pharmacology : RTP, 2008, Volume: 51, Issue:3 Suppl

    Topics: Acrylamide; Animals; Environmental Exposure; Environmental Monitoring; Epoxy Compounds; Glutathione; Guidelines as Topic; Hemoglobins; Humans; Models, Biological; Risk Assessment; Risk Management; Valine

2008
Development of a stable isotope dilution assay for the quantitation of glycidamide and its application to foods and model systems.
    Journal of agricultural and food chemistry, 2008, Aug-13, Volume: 56, Issue:15

    Topics: Acrylamide; Carbon Radioisotopes; Coconut Oil; Epoxy Compounds; Food Analysis; Food Handling; Indicator Dilution Techniques; Linoleic Acid; Plant Oils; Solanum tuberosum; Sunflower Oil

2008
Hemoglobin adducts and mercapturic acid excretion of acrylamide and glycidamide in one study population.
    Journal of agricultural and food chemistry, 2008, Aug-13, Volume: 56, Issue:15

    Topics: Acetylcysteine; Acrylamide; Adolescent; Adult; Aged; Aged, 80 and over; Aging; Child; Diet; Epoxy Compounds; Female; Hemoglobins; Humans; Male; Middle Aged; Oxidation-Reduction; Valine

2008
Cross-sectional study on acrylamide hemoglobin adducts in subpopulations from the European Prospective Investigation into Cancer and Nutrition (EPIC) Study.
    Journal of agricultural and food chemistry, 2008, Aug-13, Volume: 56, Issue:15

    Topics: Acrylamide; Adult; Aged; Alcohol Drinking; Body Mass Index; Cohort Studies; Cross-Sectional Studies; Environmental Exposure; Epoxy Compounds; Europe; Female; Hemoglobins; Humans; Male; Middle Aged; Multicenter Studies as Topic; Neoplasms; Nutritional Physiological Phenomena; Prospective Studies; Sex Factors; Smoking

2008
Carcinogenicity of acrylamide: a computational study.
    Journal of agricultural and food chemistry, 2008, Sep-24, Volume: 56, Issue:18

    Topics: Acrylamide; Adenine; Carcinogenicity Tests; Carcinogens; Epoxy Compounds; Food Analysis; Hot Temperature; Maillard Reaction; Mathematics; Thermodynamics

2008
Validation of a food frequency questionnaire measurement of dietary acrylamide intake using hemoglobin adducts of acrylamide and glycidamide.
    Cancer causes & control : CCC, 2009, Volume: 20, Issue:3

    Topics: Acrylamide; Adult; Alcohol Drinking; Biomarkers; Body Mass Index; Cohort Studies; Databases, Factual; Diet Surveys; Epoxy Compounds; Female; Hemoglobins; Humans; Middle Aged; Regression Analysis; Reproducibility of Results; Statistics as Topic; Surveys and Questionnaires; United States; United States Food and Drug Administration

2009
Investigation of the low-dose response in the in vivo induction of micronuclei and adducts by acrylamide.
    Toxicological sciences : an official journal of the Society of Toxicology, 2009, Volume: 107, Issue:1

    Topics: Acrylamide; Analysis of Variance; Animals; Body Weight; Bone Marrow; Chromosome Aberrations; DNA Adducts; Dose-Response Relationship, Drug; Epoxy Compounds; Erythrocytes; Hemoglobins; Liver; Mice; Mice, Transgenic; Micronuclei, Chromosome-Defective; Micronucleus Tests; Regression Analysis; Reticulocytes

2009
N-Acetyl-S-(1-carbamoyl-2-hydroxy-ethyl)-L-cysteine (iso-GAMA) a further product of human metabolism of acrylamide: comparison with the simultaneously excreted other mercaptuic acids.
    Archives of toxicology, 2009, Volume: 83, Issue:7

    Topics: Acetylcysteine; Acrylamide; Carcinogens; Cysteine; Epoxy Compounds; Humans; Kinetics; Male; Molecular Structure; Oxidation-Reduction; Sensitivity and Specificity

2009
Simultaneous determination of acrylamide, its metabolite glycidamide and antipyrine in human placental perfusion fluid and placental tissue by liquid chromatography-electrospray tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008, Dec-15, Volume: 876, Issue:2

    Topics: Acrylamide; Antipyrine; Chromatography, Liquid; Epoxy Compounds; Female; Humans; Perfusion; Placenta; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2008
DNA adduct formation and induction of micronuclei and mutations in B6C3F1/Tk mice treated neonatally with acrylamide or glycidamide.
    International journal of cancer, 2009, May-01, Volume: 124, Issue:9

    Topics: Acrylamide; Animals; Animals, Newborn; Body Weight; Cell Nucleus; DNA Adducts; Epoxy Compounds; Erythrocytes; Female; Hypoxanthine Phosphoribosyltransferase; Loss of Heterozygosity; Lymphocytes; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagenicity Tests; Mutation; Reticulocytes; Thymidine Kinase

2009
Biomarkers of human exposure to acrylamide and relation to polymorphisms in metabolizing genes.
    Toxicological sciences : an official journal of the Society of Toxicology, 2009, Volume: 108, Issue:1

    Topics: Acrylamide; Adult; Aged; Biomarkers, Pharmacological; Chi-Square Distribution; Cytochrome P-450 CYP2E1; Epoxide Hydrolases; Epoxy Compounds; Female; Glutathione S-Transferase pi; Glutathione Transferase; Hemoglobins; Humans; Inactivation, Metabolic; Male; Middle Aged; Polymorphism, Genetic; Statistics, Nonparametric

2009
Effect of sulforaphane on glutathione-adduct formation and on glutathione_S_transferase-dependent detoxification of acrylamide in Caco-2 cells.
    Molecular nutrition & food research, 2009, Volume: 53, Issue:12

    Topics: Acrylamide; Anticarcinogenic Agents; Caco-2 Cells; Carcinogens; Chromatography, High Pressure Liquid; Epoxy Compounds; Food Contamination; Glutathione; Glutathione Transferase; Humans; Hydrogen-Ion Concentration; Isothiocyanates; Magnetic Resonance Spectroscopy; Metabolic Detoxication, Phase II; Molecular Structure; Spectrometry, Mass, Electrospray Ionization; Sulfoxides; Tandem Mass Spectrometry; Thiocyanates; Time Factors

2009
Development of a physiologically-based toxicokinetic model of acrylamide and glycidamide in rats and humans.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2010, Volume: 48, Issue:2

    Topics: Acrylamide; Animals; Carcinogens; Computer Simulation; Epoxy Compounds; Hemoglobins; Humans; Male; Models, Biological; Neurotoxins; Rats; Rats, Inbred F344; Species Specificity

2010
Estimation of safe dietary intake levels of acrylamide for humans.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2010, Volume: 48, Issue:2

    Topics: Acrylamide; Administration, Oral; Animals; Area Under Curve; Carcinogens; Diet; Dose-Response Relationship, Drug; Environmental Exposure; Epoxy Compounds; Female; Food Contamination; Humans; Male; Maximum Allowable Concentration; Neurotoxins; Rats; Risk Assessment

2010
Simultaneous quantification of haemoglobin adducts of ethylene oxide, propylene oxide, acrylonitrile, acrylamide and glycidamide in human blood by isotope-dilution GC/NCI-MS/MS.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010, Oct-01, Volume: 878, Issue:27

    Topics: Acrylamide; Acrylonitrile; Calibration; Environmental Exposure; Epoxy Compounds; Ethylene Oxide; Gas Chromatography-Mass Spectrometry; Hemoglobins; Humans; Limit of Detection; Pilot Projects; Reference Standards; Reproducibility of Results; Tandem Mass Spectrometry

2010
In vitro investigations of glycidamide-induced DNA lesions in mouse male germ cells and in mouse and human lymphocytes.
    Mutation research, 2010, Volume: 696, Issue:1

    Topics: Acrylamide; Animals; DNA Damage; DNA Repair; Epoxy Compounds; Humans; Lymphocytes; Male; Mice; Mutagens; Spermatids

2010
Exposure of the U.S. population to acrylamide in the National Health and Nutrition Examination Survey 2003-2004.
    Environmental health perspectives, 2010, Volume: 118, Issue:2

    Topics: Acrylamide; Adolescent; Adult; Child; Child, Preschool; Environmental Exposure; Epoxy Compounds; Female; Health Surveys; Hemoglobins; Humans; Male; Middle Aged; Nutrition Surveys; Young Adult

2010
The genotoxicity of acrylamide and glycidamide in big blue rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 115, Issue:2

    Topics: Acrylamide; Animals; DNA Mutational Analysis; Epoxy Compounds; Female; Hypoxanthine Phosphoribosyltransferase; Lymphocytes; Male; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagenicity Tests; Mutagens; Mutation; Rats; Rats, Transgenic; Spleen

2010
Genotoxicity of acrylamide in vitro: Acrylamide is not metabolically activated in standard in vitro systems.
    Environmental and molecular mutagenesis, 2011, Volume: 52, Issue:1

    Topics: Acrylamide; Blotting, Western; Cell Line, Tumor; Cytochrome P-450 CYP2E1; DNA Adducts; DNA Damage; Epoxy Compounds; Humans; Microsomes, Liver; Salmonella

2011
Mutagenicity of acrylamide and glycidamide in the testes of big blue mice.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 117, Issue:1

    Topics: Acrylamide; Animals; Base Sequence; Body Weight; DNA Primers; Epoxy Compounds; Male; Mice; Mice, Mutant Strains; Mutagens; Polymerase Chain Reaction; Testis

2010
Dietary acrylamide exposure and hemoglobin adducts--National Health and Nutrition Examination Survey (2003-04).
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2010, Volume: 48, Issue:11

    Topics: Acrylamide; Adolescent; Adult; Biomarkers; Child; Child, Preschool; Cotinine; Diet; Eating; Environmental Exposure; Epoxy Compounds; Feeding Behavior; Female; Food Contamination; Health Surveys; Hemoglobins; Humans; Male; Nutrition Surveys; Surveys and Questionnaires; United States; Young Adult

2010
Food contaminant acrylamide increases expression of Cox-2 and nitric oxide synthase in breast epithelial cells.
    Toxicology and industrial health, 2011, Volume: 27, Issue:1

    Topics: Acrylamide; Carcinogens; Cell Line; Cooking; Cyclooxygenase 2; Epithelial Cells; Epoxy Compounds; Female; Food Contamination; Humans; Imidazoles; Nitric Oxide Synthase Type II

2011
Biological effects of acrylamide after daily ingestion of various foods in comparison to water: a study in rats.
    Molecular nutrition & food research, 2011, Volume: 55, Issue:3

    Topics: Acetylcysteine; Acrylamide; Animals; Biological Availability; Biomarkers; Biotransformation; Bread; Carcinogens; DNA Damage; Eating; Epoxy Compounds; Food; Hemoglobins; Male; Rats; Rats, Sprague-Dawley; Solanum tuberosum; Water

2011
In vivo doses of acrylamide and glycidamide in humans after intake of acrylamide-rich food.
    Toxicological sciences : an official journal of the Society of Toxicology, 2011, Volume: 119, Issue:1

    Topics: Acrylamide; Adult; Area Under Curve; Biotransformation; Eating; Epoxy Compounds; Female; Food; Hemoglobins; Humans; Male; Middle Aged; Models, Biological; Risk Assessment; Young Adult

2011
Excretion of 2,3-dihydroxy-propionamide (OH-PA), the hydrolysis product of glycidamide, in human urine after single oral dose of deuterium-labeled acrylamide.
    Archives of toxicology, 2011, Volume: 85, Issue:6

    Topics: Acetamides; Acetylcysteine; Acrylamide; Adult; Amides; Analytic Sample Preparation Methods; Carcinogens; Cysteine; Deuterium; Epoxy Compounds; Fluoroacetates; Gas Chromatography-Mass Spectrometry; Humans; Hydrolysis; Indicators and Reagents; Male; Organosilicon Compounds; Oxidation-Reduction; Silanes; Sulfoxides; Trifluoroacetic Acid

2011
Modification of major plasma proteins by acrylamide and glycidamide: Preliminary screening by nano liquid chromatography with tandem mass spectrometry.
    Analytica chimica acta, 2011, Jan-17, Volume: 684, Issue:1-2

    Topics: Acrylamide; Blood Proteins; Chromatography, Liquid; Epoxy Compounds; Humans; Protein Binding; Proteomics; Tandem Mass Spectrometry

2011
Dietary determinants for Hb-acrylamide and Hb-glycidamide adducts in Danish non-smoking women.
    The British journal of nutrition, 2011, Volume: 105, Issue:9

    Topics: Acrylamide; Case-Control Studies; Denmark; Diet; Epoxy Compounds; Feeding Behavior; Female; Hemoglobins; Humans; Middle Aged; Postmenopause; Risk Factors

2011
Quantitative analysis by liquid chromatography-tandem mass spectrometry of glycidamide using the cob(I)alamin trapping method: validation and application to in vitro metabolism of acrylamide.
    Journal of chromatography. A, 2011, Jul-15, Volume: 1218, Issue:28

    Topics: Acrylamide; Animals; Chromatography, Liquid; Epoxy Compounds; Humans; Linear Models; Liver Extracts; Rats; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Vitamin B 12

2011
³²P-HPLC analysis of N1-(2-carboxy-2-hydroxyethyl)deoxyadenosine: a DNA adduct of the acrylamide-derived epoxide glycidamide.
    Toxicology letters, 2011, Nov-10, Volume: 207, Issue:1

    Topics: Acrylamide; Animals; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; Deoxyadenosines; DNA Adducts; Epoxy Compounds; Humans; Leukocytes, Mononuclear; Mice; Spectrophotometry, Ultraviolet

2011
Analysis of hemoglobin adducts from acrylamide, glycidamide, and ethylene oxide in paired mother/cord blood samples from Denmark.
    Chemical research in toxicology, 2011, Nov-21, Volume: 24, Issue:11

    Topics: Acrylamide; Adult; Case-Control Studies; Chromatography, Liquid; Denmark; Epoxy Compounds; Ethylene Oxide; Female; Fetal Blood; Fetus; Hemoglobins; Humans; Mass Spectrometry; Maternal Exposure; Placenta; Pregnancy; Smoking

2011
Preconceptional paternal glycidamide exposure affects embryonic gene expression: single embryo gene expression study following in vitro fertilization.
    Reproductive toxicology (Elmsford, N.Y.), 2011, Volume: 32, Issue:4

    Topics: Acrylamide; Animals; DNA Adducts; DNA Repair; Embryo, Mammalian; Embryonic Development; Epoxy Compounds; Female; Fertilization in Vitro; Gene Expression; Male; Mice; Mutagens; Paternal Exposure; Reverse Transcriptase Polymerase Chain Reaction; Spermatozoa

2011
Occupational exposure to acrylamide in closed system production plants: air levels and biomonitoring.
    Journal of toxicology and environmental health. Part A, 2012, Volume: 75, Issue:2

    Topics: Acetylcysteine; Acrylamide; Adult; Air; Air Pollutants, Occupational; Biomarkers; Chemical Industry; Confined Spaces; Environmental Monitoring; Epoxy Compounds; Equipment Contamination; Hemoglobins; Humans; Limit of Detection; National Institute for Occupational Safety and Health, U.S.; Occupational Exposure; Particulate Matter; Surface Properties; United States; Ventilation

2012
N7-glycidamide-guanine DNA adduct formation by orally ingested acrylamide in rats: a dose-response study encompassing human diet-related exposure levels.
    Chemical research in toxicology, 2012, Feb-20, Volume: 25, Issue:2

    Topics: Acrylamide; Animals; Carcinogens; Diet; DNA Adducts; Dose-Response Relationship, Drug; Epoxy Compounds; Female; Guanine; Humans; Kidney; Liver; Lung; Rats; Rats, Sprague-Dawley

2012
Tumorigenicity of acrylamide and its metabolite glycidamide in the neonatal mouse bioassay.
    International journal of cancer, 2012, Nov-01, Volume: 131, Issue:9

    Topics: Acrylamide; Adenoma, Liver Cell; Animals; Animals, Newborn; Carcinogenicity Tests; Carcinogens; DNA Adducts; DNA Damage; Epoxy Compounds; Female; Genes, ras; Liver; Liver Neoplasms; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mutation; Random Allocation

2012
Pre-diagnostic acrylamide exposure and survival after breast cancer among postmenopausal Danish women.
    Toxicology, 2012, Jun-14, Volume: 296, Issue:1-3

    Topics: Acrylamide; Aged; Biomarkers; Breast Neoplasms; Denmark; Environmental Exposure; Environmental Pollutants; Epoxy Compounds; Female; Hemoglobins; Humans; Middle Aged; Postmenopause; Risk Factors

2012
Expression analysis of hepatic mitochondria-related genes in mice exposed to acrylamide and glycidamide.
    Journal of toxicology and environmental health. Part A, 2012, Volume: 75, Issue:6

    Topics: Acrylamide; Adenosine Triphosphate; Animals; Apoptosis; Body Weight; Drinking; Epoxy Compounds; Gene Expression Profiling; Gene Expression Regulation; Glutathione; Lipid Metabolism; Male; Mice; Mice, Transgenic; Mitochondria, Liver; Mutagens; Oxidative Stress; Phosphorylation; Protein Array Analysis; Real-Time Polymerase Chain Reaction; Steroids

2012
Genetic polymorphisms in detoxification and DNA repair genes and susceptibility to glycidamide-induced DNA damage.
    Journal of toxicology and environmental health. Part A, 2012, Volume: 75, Issue:13-15

    Topics: Acrylamide; Adult; Amino Acid Substitution; Carcinogens, Environmental; DNA Damage; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; Epoxy Compounds; Female; Genetic Association Studies; Humans; Leukocytes; Male; Mutagens; Osmolar Concentration; Polymorphism, Single Nucleotide; Portugal; X-ray Repair Cross Complementing Protein 1; Young Adult

2012
The modifying effect of CYP2E1, GST, and mEH genotypes on the formation of hemoglobin adducts of acrylamide and glycidamide in workers exposed to acrylamide.
    Toxicology letters, 2012, Nov-30, Volume: 215, Issue:2

    Topics: Acrylamide; Cytochrome P-450 CYP2E1; DNA; Epoxide Hydrolases; Epoxy Compounds; Glutathione Transferase; Hemoglobins; Humans; Inactivation, Metabolic; Occupational Exposure; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Statistics, Nonparametric

2012
Birth weight, head circumference, and prenatal exposure to acrylamide from maternal diet: the European prospective mother-child study (NewGeneris).
    Environmental health perspectives, 2012, Volume: 120, Issue:12

    Topics: Acrylamide; Adult; Birth Weight; Chromatography, Liquid; Cohort Studies; Diet; Environmental Exposure; Environmental Monitoring; Environmental Pollutants; Epoxy Compounds; Europe; Female; Fetal Blood; Head; Hemoglobins; Humans; Infant, Low Birth Weight; Infant, Newborn; Mass Spectrometry; Maternal Exposure; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Regression Analysis; Surveys and Questionnaires

2012
Crispy cravings may affect baby's health: prenatal acrylamide exposure is associated with reduced birth weight.
    Environmental health perspectives, 2012, Volume: 120, Issue:12

    Topics: Acrylamide; Birth Weight; Environmental Exposure; Environmental Pollutants; Epoxy Compounds; Female; Head; Hemoglobins; Humans; Pregnancy; Prenatal Exposure Delayed Effects

2012
Dose dependent molecular effects of acrylamide and glycidamide in human cancer cell lines and human primary hepatocytes.
    Toxicology letters, 2013, Feb-27, Volume: 217, Issue:2

    Topics: Acrylamide; Blotting, Western; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Endometrial Neoplasms; Epoxy Compounds; Female; Gene Expression Regulation, Neoplastic; Hepatocytes; Humans; Oligonucleotide Array Sequence Analysis; Ovarian Neoplasms; Real-Time Polymerase Chain Reaction; RNA, Neoplasm

2013
Induction of sister chromatid exchange by acrylamide and glycidamide in human lymphocytes: role of polymorphisms in detoxification and DNA-repair genes in the genotoxicity of glycidamide.
    Mutation research, 2013, Apr-15, Volume: 752, Issue:1-2

    Topics: Acrylamide; DNA Damage; DNA Repair; Epoxy Compounds; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Inactivation, Metabolic; Isoenzymes; Lymphocytes; Mutagens; Polymorphism, Genetic; Sister Chromatid Exchange

2013
Acrylamide hemoglobin adduct levels and ovarian cancer risk: a nested case-control study.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2013, Volume: 22, Issue:4

    Topics: Acrylamide; Adult; Carcinoma, Ovarian Epithelial; Case-Control Studies; Epoxy Compounds; Female; Hemoglobins; Humans; Middle Aged; Neoplasms, Glandular and Epithelial; Nurses; Ovarian Neoplasms; Ovary; Prognosis; Prospective Studies; Risk Factors

2013
Toxicokinetics of acrylamide in primary rat hepatocytes: coupling to glutathione is faster than conversion to glycidamide.
    Archives of toxicology, 2013, Volume: 87, Issue:8

    Topics: Acetylcysteine; Acrylamide; Animals; Biomarkers; Carcinogens; Cells, Cultured; Chromatography, High Pressure Liquid; Culture Media; Cysteine; DNA Adducts; Epoxy Compounds; Glutathione; Hepatocytes; Inactivation, Metabolic; Male; Rats; Rats, Wistar; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2013
Among 10 sociodemographic and lifestyle variables, smoking is strongly associated with biomarkers of acrylamide exposure in a representative sample of the U.S. Population.
    The Journal of nutrition, 2013, Volume: 143, Issue:6

    Topics: Acrylamide; Adult; Age Factors; Alcohol Drinking; Biomarkers; Environmental Exposure; Epoxy Compounds; Female; Hemoglobins; Humans; Life Style; Liver; Male; Middle Aged; Nutrition Surveys; Regression Analysis; Sex Factors; Smoking; Socioeconomic Factors; United States

2013
Mouse spermatocytes express CYP2E1 and respond to acrylamide exposure.
    PloS one, 2014, Volume: 9, Issue:5

    Topics: Acrylamide; Animals; Cytochrome P-450 CYP2E1; DNA Adducts; Environmental Pollutants; Epoxy Compounds; Gene Expression Regulation, Enzymologic; Male; Meiosis; Mice; Oxidation-Reduction; Spermatocytes

2014
Determination of acrylamide and glycidamide in various biological matrices by liquid chromatography-tandem mass spectrometry and its application to a pharmacokinetic study.
    Talanta, 2015, Volume: 131

    Topics: Acrylamide; Administration, Oral; Animals; Chromatography, Liquid; Epoxy Compounds; Male; Rats; Rats, Sprague-Dawley; Serum; Tandem Mass Spectrometry; Tissue Distribution; Urinalysis

2015
Differences in micronucleus frequency and acrylamide adduct levels with hemoglobin between vegetarians and non-vegetarians.
    European journal of nutrition, 2015, Volume: 54, Issue:7

    Topics: Acrylamide; Adult; Body Mass Index; Diet, Vegetarian; DNA Damage; Epoxy Compounds; Erythrocytes; Feeding Behavior; Female; Folic Acid; Genomic Instability; Hemoglobins; Humans; Life Style; Linear Models; Male; Micronucleus Tests; Motor Activity; Sensitivity and Specificity; Sweden; Transferrin; Vegetarians; Vitamin B 12; Young Adult

2015
Acrylamide-induced carcinogenicity in mouse lung involves mutagenicity: cII gene mutations in the lung of big blue mice exposed to acrylamide and glycidamide for up to 4 weeks.
    Environmental and molecular mutagenesis, 2015, Volume: 56, Issue:5

    Topics: Acrylamide; Administration, Oral; Animals; DNA; Dose-Response Relationship, Drug; Epoxy Compounds; Female; Lung Neoplasms; Male; Mice, Inbred Strains; Mutagens; Mutation; Sequence Analysis, DNA; Sex Characteristics; Transcription Factors; Viral Proteins

2015
Synthesis, characterization and analysis of the acrylamide- and glycidamide-glutathione conjugates.
    Chemico-biological interactions, 2015, Jul-25, Volume: 237

    Topics: Acrylamide; Animals; Chromatography, High Pressure Liquid; Epoxy Compounds; Glutathione; Humans; Limit of Detection; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2015
Towards a biological monitoring guidance value for acrylamide.
    Toxicology letters, 2015, Aug-19, Volume: 237, Issue:1

    Topics: Acetylcysteine; Acrylamide; Biomarkers; Creatinine; Environmental Monitoring; Epoxy Compounds; Hand Disinfection; Humans; Occupational Exposure; United Kingdom

2015
Acrylamide induces accelerated endothelial aging in a human cell model.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2015, Volume: 83

    Topics: Acrylamide; Apoptosis; beta-Galactosidase; Biomarkers; Carcinogens; Cell Proliferation; Cell Survival; Cells, Cultured; Cellular Senescence; Endothelium, Vascular; Epoxy Compounds; Human Umbilical Vein Endothelial Cells; Humans; Maillard Reaction; Osmolar Concentration; Telomere Shortening; Toxicity Tests, Subchronic

2015
Dosimetry of Acrylamide and Glycidamide Over the Lifespan in a 2-Year Bioassay of Acrylamide in Wistar Han Rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 2015, Volume: 146, Issue:2

    Topics: Acrylamide; Animals; Biological Assay; Dose-Response Relationship, Drug; Epoxy Compounds; Female; Male; Pregnancy; Rats; Rats, Wistar

2015
Acrylamide and glycidamide hemoglobin adduct levels and endometrial cancer risk: A nested case-control study in nonsmoking postmenopausal women from the EPIC cohort.
    International journal of cancer, 2016, Mar-01, Volume: 138, Issue:5

    Topics: Acrylamide; Biomarkers; Case-Control Studies; Endometrial Neoplasms; Epoxy Compounds; Female; Hemoglobins; Humans; Middle Aged; Postmenopause; Prospective Studies; Risk

2016
Acrylamide and Glycidamide Hemoglobin Adducts and Epithelial Ovarian Cancer: A Nested Case-Control Study in Nonsmoking Postmenopausal Women from the EPIC Cohort.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2016, Volume: 25, Issue:1

    Topics: Acrylamide; Adenocarcinoma, Clear Cell; Adenocarcinoma, Mucinous; Biomarkers; Case-Control Studies; Cystadenocarcinoma, Serous; Endometrial Neoplasms; Epoxy Compounds; Female; Follow-Up Studies; Hemoglobins; Humans; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Nutrition Assessment; Ovarian Neoplasms; Postmenopause; Prognosis; Prospective Studies; Risk Factors

2016
Dietary and lifestyle determinants of acrylamide and glycidamide hemoglobin adducts in non-smoking postmenopausal women from the EPIC cohort.
    European journal of nutrition, 2017, Volume: 56, Issue:3

    Topics: Acrylamide; Case-Control Studies; Cross-Sectional Studies; Diet; Epoxy Compounds; Female; Hemoglobins; Humans; Life Style; Linear Models; Middle Aged; Neoplasms; Nutrition Assessment; Postmenopause; Surveys and Questionnaires; Tandem Mass Spectrometry

2017
Generation of Desired Aroma-Active as Well as Undesired Toxicologically Relevant Compounds during Deep-Frying of Potatoes with Different Edible Vegetable Fats and Oils.
    Journal of agricultural and food chemistry, 2016, Nov-30, Volume: 64, Issue:47

    Topics: Acrolein; Acrylamide; Color; Consumer Behavior; Cooking; Epoxy Compounds; Fatty Acids; Furans; Gas Chromatography-Mass Spectrometry; Hot Temperature; Humans; Odorants; Plant Oils; Smell; Solanum tuberosum; Taste

2016
Evaluation of cII gene mutation in the brains of Big Blue mice exposed to acrylamide and glycidamide in drinking water.
    The Journal of toxicological sciences, 2016, Volume: 41, Issue:6

    Topics: Acrylamide; Administration, Oral; Animals; Brain; DNA Mutational Analysis; Dose-Response Relationship, Drug; Drinking Water; Epoxy Compounds; Female; Male; Mice, Transgenic; Mutagenesis; Mutagenicity Tests; Mutation; Sex Factors; Transcription Factors; Viral Proteins; Water Pollutants, Chemical

2016
Evidence of acrylamide- and glycidamide-induced oxidative stress and apoptosis in Leydig and Sertoli cells.
    Human & experimental toxicology, 2017, Volume: 36, Issue:12

    Topics: Acrylamide; Animals; Apoptosis; Cell Line; Cell Survival; Environmental Pollutants; Epoxy Compounds; Gene Expression Regulation; Hydrogen Peroxide; Leydig Cells; Lipid Peroxidation; Male; Malondialdehyde; Mice; Oxidative Stress; RNA, Messenger; Sertoli Cells

2017
In Vivo acrylamide exposure may cause severe toxicity to mouse oocytes through its metabolite glycidamide.
    PloS one, 2017, Volume: 12, Issue:2

    Topics: Acrylamide; Animals; Cells, Cultured; Epoxy Compounds; Female; Mice; Mice, Inbred BALB C; Oocytes; Spindle Apparatus

2017
Relationships between acrylamide and glycidamide hemoglobin adduct levels and allergy-related outcomes in general US population, NHANES 2005-2006.
    Environmental pollution (Barking, Essex : 1987), 2017, Volume: 225

    Topics: Acrylamide; Adult; Animals; Asthma; Environmental Exposure; Epoxy Compounds; Female; Hemoglobins; Humans; Hypersensitivity; Logistic Models; Male; Middle Aged; Nutrition Surveys; Odds Ratio; Rhinitis, Allergic, Seasonal; United States

2017
The influence of demographic, physical, behavioral, and dietary factors on hemoglobin adduct levels of acrylamide and glycidamide in the general U.S. population.
    Critical reviews in food science and nutrition, 2018, Mar-24, Volume: 58, Issue:5

    Topics: Acrylamide; Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Diet; Epoxy Compounds; Female; Hemoglobins; Humans; Male; Middle Aged; Nutrition Surveys; United States; Young Adult

2018
Biomarker analysis of hemoglobin adducts of acrylamide and glycidamide enantiomers for mid-term internal exposure assessment by isotope dilution ultra-high performance liquid chromatography tandem mass spectrometry.
    Talanta, 2018, Feb-01, Volume: 178

    Topics: Acrylamide; Animals; Biomarkers; Blood Chemical Analysis; Chromatography, High Pressure Liquid; Environmental Exposure; Environmental Pollutants; Epoxy Compounds; Female; Hemoglobins; Male; Rats; Rats, Sprague-Dawley; Stereoisomerism; Tandem Mass Spectrometry

2018
Using the comet assay and lysis conditions to characterize DNA lesions from the acrylamide metabolite glycidamide.
    Mutagenesis, 2018, 02-24, Volume: 33, Issue:1

    Topics: Acrylamide; Animals; Cattle; Chromatography, Liquid; Comet Assay; DNA; DNA Adducts; DNA Damage; DNA Repair; DNA-Formamidopyrimidine Glycosylase; Epoxy Compounds; Humans; Hydrogen-Ion Concentration; Lymphocytes; Mass Spectrometry; Mutagens

2018
Parallelogram based approach for in vivo dose estimation of genotoxic metabolites in humans with relevance to reduction of animal experiments.
    Scientific reports, 2017, 12-14, Volume: 7, Issue:1

    Topics: Acrylamide; Animals; Dose-Response Relationship, Drug; Epoxy Compounds; Hemoglobins; Humans; Mice; Mutagenicity Tests; Mutagens; Neoplasms; Rats; Risk Assessment; Statistics as Topic; Uncertainty

2017
Protection of cyanidin-3-O-glucoside against acrylamide- and glycidamide-induced reproductive toxicity in leydig cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2018, Volume: 119

    Topics: Acrylamide; Animals; Anthocyanins; Apoptosis; Cell Line; Dose-Response Relationship, Drug; Epoxy Compounds; Glucosides; Leydig Cells; Male; Membrane Potential, Mitochondrial; Mice; Progesterone; Reactive Oxygen Species; Reproduction

2018
Toxicogenomic evaluation of liver responses induced by acrylamide and glycidamide in male mouse liver.
    General physiology and biophysics, 2018, Volume: 37, Issue:2

    Topics: Acrylamide; Animals; Epoxy Compounds; Liver; Male; Mice; Mice, Inbred BALB C

2018
High-throughput, simultaneous quantitation of hemoglobin adducts of acrylamide, glycidamide, and ethylene oxide using UHPLC-MS/MS.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2018, Jun-01, Volume: 1086

    Topics: Acrylamide; Adult; Aged; Chromatography, High Pressure Liquid; Environmental Exposure; Epoxy Compounds; Ethylene Oxide; Hemoglobins; High-Throughput Screening Assays; Humans; Limit of Detection; Linear Models; Middle Aged; Reproducibility of Results; Tandem Mass Spectrometry; Young Adult

2018
The polymorphism rs2480258 within CYP2E1 is associated with different rates of acrylamide metabolism in vivo in humans.
    Archives of toxicology, 2018, Volume: 92, Issue:6

    Topics: Acrylamide; Adult; Biotransformation; Cytochrome P-450 CYP2E1; Epoxy Compounds; Female; Gene Frequency; Genotype; Healthy Volunteers; Humans; Male; Polymorphism, Single Nucleotide

2018
Dose-dependent synergistic and antagonistic mutation responses of binary mixtures of the environmental carcinogen benzo[a]pyrene with food-derived carcinogens.
    Archives of toxicology, 2018, Volume: 92, Issue:12

    Topics: Acrylamide; Benzo(a)pyrene; Carcinogens; Carcinogens, Environmental; Cell Line; DNA Damage; Dose-Response Relationship, Drug; Drug Synergism; Epoxy Compounds; Food; Humans; Imidazoles; Mutagenesis; Mutagenicity Tests; Mutagens; Mutation

2018
Changes of metabolites of acrylamide and glycidamide in acrylamide-exposed rats pretreated with blueberry anthocyanins extract.
    Food chemistry, 2019, Feb-15, Volume: 274

    Topics: Acetylcysteine; Acrylamide; Animals; Anthocyanins; Blueberry Plants; Cytoprotection; DNA Adducts; Epoxy Compounds; Female; Guanine; Rats; Rats, Sprague-Dawley

2019
Beyond detoxification: Pleiotropic functions of multiple glutathione S-transferase isoforms protect mice against a toxic electrophile.
    PloS one, 2019, Volume: 14, Issue:11

    Topics: Acrylamide; Animals; Disease Models, Animal; Epoxy Compounds; Female; Gene Deletion; Glutathione; Glutathione Transferase; Humans; Inactivation, Metabolic; Isoenzymes; Liver; Male; Mice; Mutagenicity Tests

2019
Rapid Simultaneous Determination of Cascade Metabolites of Acrylamide in Urine for Toxicokinetics Profiles and Short-Term Dietary Internal Exposure.
    Journal of agricultural and food chemistry, 2020, Jun-17, Volume: 68, Issue:24

    Topics: Acrylamide; Adult; Animals; Biomarkers; Chromatography, High Pressure Liquid; Dietary Exposure; Epoxy Compounds; Female; Food Contamination; Humans; Male; Rats; Rats, Sprague-Dawley; Toxicokinetics; Young Adult

2020
Association between acrylamide exposure and sex hormones in males: NHANES, 2003-2004.
    PloS one, 2020, Volume: 15, Issue:6

    Topics: Acrylamide; Adolescent; Adult; Child; Cohort Studies; Environmental Exposure; Epoxy Compounds; Gonadal Steroid Hormones; Hemoglobins; Humans; Male; Middle Aged; Nutrition Surveys; Sex Hormone-Binding Globulin; United States; Young Adult

2020
Protective effect of a dietary flavonoid-rich antioxidant from bamboo leaves against internal exposure to acrylamide and glycidamide in humans.
    Food & function, 2020, Aug-01, Volume: 11, Issue:8

    Topics: Acetylcysteine; Acrylamide; Adolescent; Antioxidants; Biomarkers; Dietary Exposure; Epoxy Compounds; Female; Flavones; Glycosides; Hemoglobins; Humans; Male; Plant Leaves; Protective Agents; Sasa; Students; Universities; Young Adult

2020
Mutagenicity of acrylamide and glycidamide in human TP53 knock-in (Hupki) mouse embryo fibroblasts.
    Archives of toxicology, 2020, Volume: 94, Issue:12

    Topics: Acrylamide; Animals; Cell Line; DNA Mutational Analysis; Epoxy Compounds; Fibroblasts; Gene Expression Regulation; Gene Knock-In Techniques; Humans; Mice; Mutagenesis; Mutagens; Tumor Suppressor Protein p53; Whole Genome Sequencing

2020
Acrylamide and its metabolite induce neurotoxicity via modulation of protein kinase C and AMP-activated protein kinase pathways.
    Toxicology in vitro : an international journal published in association with BIBRA, 2021, Volume: 72

    Topics: Acrylamide; AMP-Activated Protein Kinases; Animals; Autophagy; Cytochrome P-450 CYP2E1; Epoxy Compounds; Extracellular Signal-Regulated MAP Kinases; Neurotoxicity Syndromes; PC12 Cells; Protein Kinase C; Rats; RNA, Small Interfering

2021
Association of acrylamide and glycidamide haemoglobin adduct levels with diabetes mellitus in the general population.
    Environmental pollution (Barking, Essex : 1987), 2021, May-15, Volume: 277

    Topics: Acrylamide; Adult; Aged; Diabetes Mellitus; Epoxy Compounds; Hemoglobins; Humans; Nutrition Surveys

2021
Association of acrylamide hemoglobin biomarkers with serum lipid levels in general US population: NHANES 2013-2016.
    Ecotoxicology and environmental safety, 2021, Volume: 214

    Topics: Acrylamide; Adult; Biomarkers; Cholesterol; Epoxy Compounds; Female; Hemoglobins; Humans; Linear Models; Male; Middle Aged; Nutrition Surveys; Regression Analysis; Triglycerides; United States; Young Adult

2021
Cord blood acrylamide levels and birth size, and interactions with genetic variants in acrylamide-metabolising genes.
    Environmental health : a global access science source, 2021, 04-01, Volume: 20, Issue:1

    Topics: Acrylamide; Adult; Birth Weight; Cytochrome P-450 CYP2E1; Epoxide Hydrolases; Epoxy Compounds; Female; Fetal Blood; Glutathione S-Transferase pi; Hemoglobins; Humans; Infant, Newborn; Male; Maternal Exposure; Maternal-Fetal Exchange; Polymorphism, Single Nucleotide; Pregnancy

2021
Health risks of dual use of electronic and combustible cigarettes: exposure to acrylamide and glycidamide.
    Polish archives of internal medicine, 2022, 01-28, Volume: 132, Issue:1

    Topics: Acrylamide; Adolescent; Adult; Cross-Sectional Studies; Electronic Nicotine Delivery Systems; Electronics; Epoxy Compounds; Hemoglobins; Humans; Nutrition Surveys; Tobacco Products; United States

2022
Characterization of primary glutathione conjugates with acrylamide and glycidamide: Toxicokinetic studies in Sprague Dawley rats treated with acrylamide.
    Chemico-biological interactions, 2021, Dec-01, Volume: 350

    Topics: Acrylamide; Animals; Carcinogens; Epoxy Compounds; Female; Glutathione; Humans; Male; Metabolic Networks and Pathways; Models, Biological; Rats; Rats, Sprague-Dawley; Toxicokinetics

2021
A Benchmark analysis of acrylamide-derived DNA adducts in rat hepatocytes in culture measured by a new, highly sensitive method.
    Toxicology, 2021, Volume: 464

    Topics: Acrylamide; Animals; Benchmarking; Carcinogens; DNA Adducts; Dose-Response Relationship, Drug; Epoxy Compounds; Hepatocytes; Male; Rats; Rats, Wistar

2021
Determination of N7-glycidamide guanine adducts in human blood DNA following exposure to dietary acrylamide using liquid chromatography/tandem mass spectrometry.
    Rapid communications in mass spectrometry : RCM, 2022, Mar-30, Volume: 36, Issue:6

    Topics: Acrylamide; Chromatography, Liquid; Dietary Exposure; DNA; DNA Adducts; Epoxy Compounds; Guanine; Humans; Lymphocytes; Tandem Mass Spectrometry

2022
The construction and application of physiologically based toxicokinetic models for acrylamide, glycidamide and their biomarkers in rats and humans.
    Chemosphere, 2022, Volume: 292

    Topics: Acetylcysteine; Acrylamide; Animals; Biomarkers; Epoxy Compounds; Humans; Rats; Toxicokinetics

2022
Catechins protect against acrylamide- and glycidamide-induced cellular toxicity via rescuing cellular apoptosis and DNA damage.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2022, Volume: 167

    Topics: Acrylamide; Apoptosis; Catechin; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; DNA Damage; Epoxy Compounds; Humans; Poly(ADP-ribose) Polymerase Inhibitors

2022
Glycidamide and cis-2-butene-1,4-dial (BDA) as potential carcinogens and promoters of liver cancer - An in vitro study.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2022, Volume: 166

    Topics: Acrylamide; Aldehydes; Animals; Carcinogenesis; Carcinogens; Carcinoma, Hepatocellular; Epoxy Compounds; Furans; Liver Neoplasms

2022
Associations of Hemoglobin Adducts of Acrylamide and Glycidamide with Prevalent Metabolic Syndrome in a Nationwide Population-Based Study.
    Journal of agricultural and food chemistry, 2022, Jul-20, Volume: 70, Issue:28

    Topics: Acrylamide; Adult; Biomarkers; Epoxy Compounds; Glucose; Hemoglobins; Humans; Hypertriglyceridemia; Metabolic Syndrome; Obesity; Obesity, Abdominal

2022
Developmental neurotoxicity of acrylamide and its metabolite glycidamide in a human mixed culture of neurons and astrocytes undergoing differentiation in concentrations relevant for human exposure.
    Neurotoxicology, 2022, Volume: 92

    Topics: Acrylamide; Astrocytes; Brain-Derived Neurotrophic Factor; Epoxy Compounds; Female; Humans; Induced Pluripotent Stem Cells; Infant, Newborn; Microtubule-Associated Proteins; Nestin; Neurons; Neurotoxicity Syndromes; Pregnancy; Tubulin

2022
Adolescence is a sensitive period for acrylamide-induced sex hormone disruption: Evidence from NHANES populations and experimental mice.
    Ecotoxicology and environmental safety, 2023, Jan-01, Volume: 249

    Topics: Acrylamide; Adolescent; Animals; Biomarkers; Child; Endocrine Disruptors; Environmental Pollutants; Estradiol; Female; Gonadal Steroid Hormones; Gonadotropin-Releasing Hormone; Humans; Male; Mice; Nutrition Surveys; Puberty; Sexual Maturation; Testosterone; Young Adult

2023
Acrylamide and Glycidamide Hemoglobin Adduct Levels and Breast Cancer Risk in Japanese Women: A Nested Case-Control Study in the JPHC.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2023, 03-06, Volume: 32, Issue:3

    Topics: Acrylamide; Biomarkers; Breast Neoplasms; Case-Control Studies; East Asian People; Epoxy Compounds; Female; Hemoglobins; Humans; Logistic Models; Prospective Studies

2023
Relationship between acrylamide and glycidamide hemoglobin adduct levels and osteoarthritis: a NHANES analysis.
    Environmental science and pollution research international, 2023, Volume: 30, Issue:30

    Topics: Acrylamide; Adult; Aged; Aged, 80 and over; Biomarkers; Epoxy Compounds; Hemoglobins; Humans; Middle Aged; Nutrition Surveys; Osteoarthritis

2023
Ultra-processed food consumption and exposure to acrylamide in a nationally representative sample of the US population aged 6 years and older.
    Preventive medicine, 2023, Volume: 174

    Topics: Acrylamide; Cardiovascular Diseases; Cross-Sectional Studies; Diet; Fast Foods; Food Handling; Food, Processed; Hemoglobins; Humans; Male; Neoplasms; Nutrition Surveys; Young Adult

2023
Determinants of exposure to acrylamide in European children and adults based on urinary biomarkers: results from the "European Human Biomonitoring Initiative" HBM4EU participating studies.
    Scientific reports, 2023, Dec-02, Volume: 13, Issue:1

    Topics: Acrylamide; Adolescent; Adult; Biological Monitoring; Biomarkers; Child; Child, Preschool; Creatinine; Humans; Middle Aged; Surveys and Questionnaires; Young Adult

2023