acrolein has been researched along with perfosfamide in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (35.71) | 18.7374 |
| 1990's | 6 (42.86) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Farquhar, D; Wang, YQ | 1 |
| Little, SA; Mirkes, PE | 1 |
| Chapman, MY; Holsapple, MP; Kawabata, TT; Kim, DH; Stevens, WD | 1 |
| Blomgren, H; Hallström, M | 1 |
| Kohn, FR; Sladek, NE | 1 |
| Kawabata, TT; White, KL | 1 |
| Brendel, M; Fleer, R | 1 |
| Borch, RF; Low, JE; Sladek, NE | 1 |
| Jacob-Müller, U; Spielmann, H | 1 |
| Dorr, RT; Lagel, K | 1 |
| Chang, TK; Waxman, DJ | 1 |
| Adams, DJ; Boal, JH; Colvin, OM; Flowers, JL; Gamcsik, MP; Ludeman, SM; Shao, KL; Springer, JB | 1 |
| Dabrowiak, JC; Goodisman, J; Souid, AK; Tacka, KA | 1 |
| Desmeules, P; Devine, PJ | 1 |
14 other study(ies) available for acrolein and perfosfamide
| Article | Year |
|---|---|
Aldophosphamide acetal diacetate and structural analogues: synthesis and cytotoxicity studies.
Topics: Animals; Antineoplastic Agents; Carboxylesterase; Carboxylic Ester Hydrolases; Cell Survival; Drug Screening Assays, Antitumor; Leukemia L1210; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; Phosphoramide Mustards; Prodrugs; Structure-Activity Relationship | 1991 |
Effects of 4-hydroperoxycyclophosphamide (4-OOH-CP) and 4-hydroperoxydechlorocyclophosphamide (4-OOH-deCICP) on the cell cycle of post implantation rat embryos.
Topics: Abnormalities, Drug-Induced; Acrolein; Animals; Biotransformation; Cell Cycle; Cell Separation; Culture Techniques; Cyclophosphamide; DNA; Embryo, Mammalian; Female; Flow Cytometry; Osmolar Concentration; Phosphoramide Mustards; Pregnancy; Rats; Teratogens | 1992 |
Mechanisms of in vitro immunosuppression by hepatocyte-generated cyclophosphamide metabolites and 4-hydroperoxycyclophosphamide.
Topics: Acrolein; Animals; Antibody Formation; Cell Survival; Cells, Cultured; Cyclophosphamide; DNA; Female; Liver; Mesna; Mice; Spleen | 1990 |
Possible role of acrolein in oxazaphosphorine-induced enhancement of immunological reactivity.
Topics: Acrolein; Aldehydes; Antineoplastic Agents; Concanavalin A; Cyclophosphamide; Humans; Immunity, Cellular; Lymphocytes; Mitogens; Mitosis; T-Lymphocytes; T-Lymphocytes, Regulatory | 1990 |
Aldehyde dehydrogenase activity as the basis for the relative insensitivity of murine pluripotent hematopoietic stem cells to oxazaphosphorines.
Topics: Acrolein; Aldehyde Dehydrogenase; Animals; Bone Marrow Cells; Cisplatin; Colony-Forming Units Assay; Cyanamide; Cyclophosphamide; Disulfiram; Ditiocarb; Drug Synergism; Granulocytes; Hematopoietic Stem Cells; Male; Melphalan; Mice; Mice, Inbred BALB C; Nitrogen Mustard Compounds; Organophosphorus Compounds; Phosphinic Acids; Phosphoramide Mustards | 1985 |
Enhancement of in vivo and in vitro murine immune responses by the cyclophosphamide metabolite acrolein.
Topics: Acrolein; Aldehydes; Animals; Antibody-Producing Cells; Cell Survival; Cyclophosphamide; Female; Hypersensitivity, Delayed; Immunity; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Phosphoramide Mustards; Sulfhydryl Compounds; T-Lymphocytes | 1988 |
Toxicity, interstrand cross-links and DNA fragmentation induced by 'activated' cyclophosphamide in yeast: comparative studies on 4-hydroperoxy-cyclophosphamide, its monofunctional analogon, acrolein, phosphoramide mustard, and nor-nitrogen mustard.
Topics: Acrolein; Alkylating Agents; Biotransformation; Cross-Linking Reagents; Cyclophosphamide; DNA; Nitrogen Mustard Compounds; Phosphoramide Mustards; Saccharomyces cerevisiae; Time Factors | 1982 |
Conversion of 4-hydroperoxycyclophosphamide and 4-hydroxycyclophosphamide to phosphoramide mustard and acrolein mediated by bifunctional catalysis.
Topics: Acrolein; Biotransformation; Buffers; Chemical Phenomena; Chemistry; Cyclophosphamide; Humans; Hydrogen-Ion Concentration; Kinetics; Liver; Magnetic Resonance Spectroscopy; Phosphoramide Mustards | 1982 |
Investigation on cyclophosphamide treatment during the preimplantation period. II. In vitro studies on the effects of cyclophosphamide and its metabolites 4-OH-cyclophosphamide, phosphoramide mustard, and acrolein on blastulation of four-cell and eight-ce
Topics: Acrolein; Aldehydes; Animals; Blastocyst; Cyclophosphamide; Dose-Response Relationship, Drug; Embryonic Development; Female; Mice; Phosphoramide Mustards; Pregnancy; Teratogens | 1981 |
Effect of sulfhydryl compounds and glutathione depletion on rat heart myocyte toxicity induced by 4-hydroperoxycyclophosphamide and acrolein in vitro.
Topics: Acrolein; Animals; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Cyclophosphamide; Glutathione; Heart; In Vitro Techniques; Methionine Sulfoximine; Muscle Proteins; Rats; Sulfhydryl Compounds | 1994 |
Cyclophosphamide modulates rat hepatic cytochrome P450 2C11 and steroid 5 alpha-reductase activity and messenger RNA levels through the combined action of acrolein and phosphoramide mustard.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Acrolein; Animals; Aryl Hydrocarbon Hydroxylases; Cyclophosphamide; Cytochrome P-450 Enzyme System; Drug Combinations; Ifosfamide; Male; Phosphoramide Mustards; Rats; Rats, Inbred F344; RNA, Messenger; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Testosterone | 1993 |
Evidence for a role of chloroethylaziridine in the cytotoxicity of cyclophosphamide.
Topics: Acrolein; Antineoplastic Agents, Alkylating; Aziridines; Breast Neoplasms; Cell Count; Cell Nucleus; Cell Survival; Cyclophosphamide; Humans; Indicators and Reagents; Kinetics; Magnetic Resonance Spectroscopy; Tumor Cells, Cultured | 2000 |
Kinetic analysis of the reactions of 4-hydroperoxycyclophosphamide and acrolein with glutathione, mesna, and WR-1065.
Topics: Acrolein; Antineoplastic Agents, Alkylating; Cell Membrane; Cyclophosphamide; Glutathione; Humans; In Vitro Techniques; Kinetics; Leukocytes, Mononuclear; Mercaptoethylamines; Mesna; Protective Agents | 2002 |
Characterizing the ovotoxicity of cyclophosphamide metabolites on cultured mouse ovaries.
Topics: Acrolein; Animals; Cyclophosphamide; Female; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Ovarian Follicle; Phosphoramide Mustards | 2006 |