Page last updated: 2024-08-18

acrolein and oligonucleotides

acrolein has been researched along with oligonucleotides in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.14)18.2507
2000's8 (57.14)29.6817
2010's5 (35.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Meerman, JH; Nelson, SD; van Beerendonk, GJ1
Harris, CM; Harris, TM; Nechev, LV1
Brock, AK; Harris, TM; Kozekov, ID; Nechev, LV; Rizzo, CJ1
Frank, EG; Hanaoka, F; Miller, H; Moriya, M; Ohmori, H; Wang, Z; Yang, IY1
Cecilia Torres, M; Huang, Y; Iden, CR; Johnson, F1
Kanuri, M; Kurtz, AJ; Lloyd, RS; Minko, IG; Moriya, M; Sanchez, AM1
Borbone, N; D'Isa, G; Mayol, L; Oliviero, G; Piccialli, G; Varra, M1
Cho, YJ; Harris, TM; Huang, H; Jacob, J; Kim, HY; Kozekov, ID; Kozekova, A; Lloyd, RS; Minko, IG; Nechev, LV; Rizzo, CJ; Slutsky, A; Stone, MP; Tamura, P; Voehler, M; Wang, H1
Ban, JO; Hong, JT; Jung, JK; Lee, CW; Lee, JW; Lee, SH; Lee, SY; Moon, DC; Oh, KW; Yoo, HS1
Breslauer, KJ; Iden, CR; Johnson, F; Minetti, CA; Remeta, DP1
Bonala, R; de los Santos, C; El-khateeb, M; Johnson, F; Lukin, M; Zaliznyak, T1
Liu, XY; Xie, JP; Zhu, MX1
Copeland, WC; Kasiviswanathan, R; Lloyd, RS; Minko, IG1
Delaney, JC; Essigmann, JM; Fedeles, BI; Kozekov, ID; Kozekova, A; Li, D; Marnett, LJ; Rizzo, CJ; Singh, V1

Reviews

2 review(s) available for acrolein and oligonucleotides

ArticleYear
Metabolism and genotoxicity of the halogenated alkyl compound tris(2,3-dibromopropyl)phosphate.
    Human & experimental toxicology, 1994, Volume: 13, Issue:12

    Topics: Acrolein; Animals; Base Sequence; Carcinogens; Cross-Linking Reagents; DNA Adducts; DNA Damage; DNA Repair; Drosophila; Flame Retardants; Liver; Molecular Sequence Data; Mutagenicity Tests; Mutagens; Oligonucleotides; Organophosphates; Rats

1994
Mutagenicity of acrolein and acrolein-induced DNA adducts.
    Toxicology mechanisms and methods, 2010, Volume: 20, Issue:1

    Topics: Acrolein; Animals; Cross-Linking Reagents; Deoxyguanosine; DNA; DNA Adducts; Humans; Lung; Mutagenicity Tests; Mutagens; Oligonucleotides

2010

Other Studies

12 other study(ies) available for acrolein and oligonucleotides

ArticleYear
Synthesis of nucleosides and oligonucleotides containing adducts of acrolein and vinyl chloride.
    Chemical research in toxicology, 2000, Volume: 13, Issue:5

    Topics: Acrolein; Chromatography, High Pressure Liquid; Deoxyadenosines; Deoxyguanosine; DNA; DNA Adducts; Ethylene Oxide; Mutagens; Nucleosides; Oligonucleotides; Vinyl Chloride

2000
DNA adducts of acrolein: site-specific synthesis of an oligodeoxynucleotide containing 6-hydroxy-5,6,7,8-tetrahydropyrimido[1,2-a]purin-10(3H)-one, an acrolein adduct of guanine.
    Chemical research in toxicology, 2002, Volume: 15, Issue:5

    Topics: Acrolein; DNA Adducts; Guanine; Oligonucleotides; Purines; Pyrimidinones

2002
Mammalian translesion DNA synthesis across an acrolein-derived deoxyguanosine adduct. Participation of DNA polymerase eta in error-prone synthesis in human cells.
    The Journal of biological chemistry, 2003, Apr-18, Volume: 278, Issue:16

    Topics: Acrolein; Cell Line; Cell Line, Transformed; Deoxyguanosine; DNA; DNA Adducts; DNA Primers; DNA-Directed DNA Polymerase; Humans; Models, Chemical; Oligonucleotide Probes; Oligonucleotides; Plasmids; Proliferating Cell Nuclear Antigen

2003
Synthesis of the minor acrolein adducts of 2(')-deoxyguanosine and their generation in oligomeric DNA.
    Bioorganic chemistry, 2003, Volume: 31, Issue:2

    Topics: Acrolein; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA Adducts; Oligonucleotides

2003
Comparative evaluation of the bioreactivity and mutagenic spectra of acrolein-derived alpha-HOPdG and gamma-HOPdG regioisomeric deoxyguanosine adducts.
    Chemical research in toxicology, 2003, Volume: 16, Issue:8

    Topics: Acrolein; Animals; Chlorocebus aethiops; COS Cells; Cross-Linking Reagents; Deoxyguanosine; DNA; DNA Adducts; Mutagenicity Tests; Oligonucleotides; Stereoisomerism

2003
Effects of acrolein on the quadruplex forming d(TTAGGG)4 telomeric repeat sequence.
    Nucleosides, nucleotides & nucleic acids, 2005, Volume: 24, Issue:5-7

    Topics: Acrolein; DNA; Humans; Magnetic Resonance Spectroscopy; Models, Chemical; Nucleic Acid Conformation; Nucleic Acid Denaturation; Nucleic Acid Heteroduplexes; Oligonucleotides; Repetitive Sequences, Nucleic Acid; Spectrometry, Mass, Electrospray Ionization; Telomere

2005
Spectroscopic characterization of interstrand carbinolamine cross-links formed in the 5'-CpG-3' sequence by the acrolein-derived gamma-OH-1,N2-propano-2'-deoxyguanosine DNA adduct.
    Journal of the American Chemical Society, 2005, Dec-21, Volume: 127, Issue:50

    Topics: Acrolein; Carbon Isotopes; CpG Islands; Cross-Linking Reagents; Deoxyguanosine; DNA; DNA Adducts; Hydrogen Bonding; Isotope Labeling; Models, Molecular; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Oligonucleotides; Oligopeptides; Stereoisomerism; Substrate Specificity

2005
2-hydroxycinnamaldehyde inhibits SW620 colon cancer cell growth through AP-1 inactivation.
    Journal of pharmacological sciences, 2007, Volume: 104, Issue:1

    Topics: Acrolein; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cinnamates; DNA-Binding Proteins; Dose-Response Relationship, Drug; Electrophoretic Mobility Shift Assay; Growth Inhibitors; Humans; In Situ Nick-End Labeling; Inhibitory Concentration 50; Luciferases; Molecular Structure; Oligonucleotides; Protein Binding; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Structure-Activity Relationship; Transcription Factor AP-1; Transfection

2007
Impact of alpha-hydroxy-propanodeoxyguanine adducts on DNA duplex energetics: opposite base modulation and implications for mutagenicity and genotoxicity.
    Biopolymers, 2010, Volume: 93, Issue:4

    Topics: Acrolein; Calorimetry, Differential Scanning; Circular Dichroism; DNA; DNA Adducts; DNA Damage; Guanine; Mutagenesis; Oligonucleotides; Thermodynamics

2010
NMR structure of duplex DNA containing the alpha-OH-PdG.dA base pair: a mutagenic intermediate of acrolein.
    Biopolymers, 2010, Volume: 93, Issue:4

    Topics: Acrolein; Deoxyadenosines; Deoxyguanosine; DNA; DNA Damage; Models, Molecular; Molecular Dynamics Simulation; Mutagens; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Oligonucleotides

2010
Translesion synthesis past acrolein-derived DNA adducts by human mitochondrial DNA polymerase γ.
    The Journal of biological chemistry, 2013, May-17, Volume: 288, Issue:20

    Topics: Acrolein; Catalytic Domain; Deoxyguanosine; DNA Adducts; DNA Damage; DNA Polymerase gamma; DNA Replication; DNA-Directed DNA Polymerase; Humans; Lipid Peroxidation; Mitochondria; Models, Chemical; Mutagenesis; Oligonucleotides; Oxidative Stress

2013
Mechanism of repair of acrolein- and malondialdehyde-derived exocyclic guanine adducts by the α-ketoglutarate/Fe(II) dioxygenase AlkB.
    Chemical research in toxicology, 2014, Sep-15, Volume: 27, Issue:9

    Topics: Acrolein; Borohydrides; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA; DNA Adducts; DNA Repair; DNA, Single-Stranded; Escherichia coli Proteins; Malondialdehyde; Mixed Function Oxygenases; Oligonucleotides; Tandem Mass Spectrometry

2014