Page last updated: 2024-08-18

acrolein and alpha-synuclein

acrolein has been researched along with alpha-synuclein in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Hashizume, Y; Maruyama, W; Naoi, M; Osawa, T; Riederer, P; Shamoto-Nagai, M; Yoshida, M1
Huang, HJ; Lin, AM; Lin, HC; Lo, YL; Wang, HT; Wang, YT; Zhao, WZ1
Acosta, G; Ambaw, A; Herr, SA; Hubers, SA; Liu, F; Pond, A; Rochet, JC; Shi, R; Strathearn, KE; Tambe, MA; Tang, J; Truong, A; Walls, E; Zheng, L1
Acosta, G; Fernandez, J; Herr, S; Race, N; Rogers, E; Shi, R; Tang, J1
Huang, HJ; Lin, AM; Lin, BW; Lo, YL; Shiao, YJ; Wang, HT; Yeh, TY1

Other Studies

5 other study(ies) available for acrolein and alpha-synuclein

ArticleYear
In parkinsonian substantia nigra, alpha-synuclein is modified by acrolein, a lipid-peroxidation product, and accumulates in the dopamine neurons with inhibition of proteasome activity.
    Journal of neural transmission (Vienna, Austria : 1996), 2007, Volume: 114, Issue:12

    Topics: Acrolein; Aged; alpha-Synuclein; Blotting, Western; Dopamine; Electrophoresis, Polyacrylamide Gel; Female; Humans; Lipid Peroxidation; Male; Melanins; Neurons; Parkinson Disease; Proteasome Endopeptidase Complex; Substantia Nigra

2007
Acrolein acts as a neurotoxin in the nigrostriatal dopaminergic system of rat: involvement of α-synuclein aggregation and programmed cell death.
    Scientific reports, 2017, 04-12, Volume: 7

    Topics: Acrolein; alpha-Synuclein; Animals; Cell Death; Disease Models, Animal; Dopaminergic Neurons; Encephalitis; Male; Oxidative Stress; Parkinsonian Disorders; Protein Aggregation, Pathological; Rats, Sprague-Dawley; Substantia Nigra

2017
Acrolein-mediated neuronal cell death and alpha-synuclein aggregation: Implications for Parkinson's disease.
    Molecular and cellular neurosciences, 2018, Volume: 88

    Topics: Acrolein; alpha-Synuclein; Animals; Cell Death; Cell Line; Dopamine; Dopaminergic Neurons; Oxidative Stress; Parkinson Disease; Rats; Spinal Cord Injuries; Substantia Nigra

2018
Acrolein-mediated alpha-synuclein pathology involvement in the early post-injury pathogenesis of mild blast-induced Parkinsonian neurodegeneration.
    Molecular and cellular neurosciences, 2019, Volume: 98

    Topics: Acrolein; alpha-Synuclein; Animals; Brain Injuries, Traumatic; Corpus Striatum; Male; Parkinson Disease, Secondary; Protein Multimerization; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tyrosine 3-Monooxygenase

2019
Neuroprotective effect of selumetinib on acrolein-induced neurotoxicity.
    Scientific reports, 2021, 06-14, Volume: 11, Issue:1

    Topics: Acrolein; alpha-Synuclein; Animals; Apoptosis; Benzimidazoles; Cells, Cultured; Cerebral Cortex; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Necroptosis; Neurodegenerative Diseases; Neuronal Outgrowth; Neurons; Neuroprotective Agents; Primary Cell Culture; Protein Aggregates; Rats; Toxicity Tests, Acute

2021