Compounds > acrolein
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acrolein and acetaminophen

acrolein has been researched along with acetaminophen in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19903 (30.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's6 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Cotgreave, I; Lindeke, B; Moldéus, P; Sun, YP1
Korsholm, B; Poulsen, HE1
Anundi, I; Dawson, JR; Moldéus, P; Norbeck, K1
Aldini, G; Andrè, E; Azzari, C; Carini, M; Carnini, C; Cerbai, E; Civelli, M; Geppetti, P; Massi, D; Materazzi, S; McGarvey, L; Nassini, R; Patacchini, R; Pedretti, P; Preti, D; Sadofsky, L; Sartiani, L; Stokesberry, S; Trevisan, G; Trevisani, M; Villetti, G1
Alenmyr, L; Andersson, A; Andersson, DA; Bevan, S; Bucher, B; Galzi, JL; Gentry, C; Högestätt, ED; Killander, D; Lewis, SE; Sterner, O; Zygmunt, PM1
Jeffery, B; Koci, J; Monteiro-Riviere, NA; Riviere, JE; Zhang, LW1
Arai, T; Kitamura, D; Koyama, R; Mizuta, R; Yuasa, M1
Andersson, DA; Bevan, S; Gentry, C1
Koyama, R; Mizuta, R1

Other Studies

10 other study(ies) available for acrolein and acetaminophen

ArticleYear
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
The metabolism of sulfite in liver. Stimulation of sulfate conjugation and effects on paracetamol and allyl alcohol toxicity.
    Biochemical pharmacology, 1989, Dec-01, Volume: 38, Issue:23

    Topics: 1-Propanol; Acetaminophen; Acrolein; Animals; Cells, Cultured; Glutathione; Liver; Male; Perfusion; Propanols; Rats; Rats, Inbred Strains; Sulfates; Sulfites

1989
Quantitative liver functions after administration of allyl alcohol to rats.
    Acta pharmacologica et toxicologica, 1984, Volume: 54, Issue:2

    Topics: 1-Propanol; Acetaminophen; Acrolein; Animals; Anisoles; Chemical and Drug Induced Liver Injury; Female; Galactose; Glutathione; Liver Function Tests; Propanols; Prothrombin Time; Rats; Rats, Inbred Strains; Time Factors

1984
The effectiveness of N-acetylcysteine in isolated hepatocytes, against the toxicity of paracetamol, acrolein, and paraquat.
    Archives of toxicology, 1984, Volume: 55, Issue:1

    Topics: Acetaminophen; Acetone; Acetylcysteine; Acrolein; Aldehydes; Amino Acids; Animals; Cell Survival; Chemical and Drug Induced Liver Injury; Glutathione; Liver; Male; Maleates; Paraquat; Phenobarbital; Rats; Rats, Inbred Strains

1984
Acetaminophen, via its reactive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2010, Volume: 24, Issue:12

    Topics: Acetaminophen; Acrolein; Analgesics, Non-Narcotic; Animals; Asthma; Benzoquinones; Bronchoalveolar Lavage; Calcium; Cell Line; Chromatography, Liquid; Guinea Pigs; Humans; Imines; Immunohistochemistry; Male; Mice; Pulmonary Disease, Chronic Obstructive; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Transient Receptor Potential Channels; TRPA1 Cation Channel

2010
TRPA1 mediates spinal antinociception induced by acetaminophen and the cannabinoid Δ(9)-tetrahydrocannabiorcol.
    Nature communications, 2011, Nov-22, Volume: 2

    Topics: Acetaminophen; Acrolein; Analgesics; Animals; Benzoquinones; Calcium; Cannabinoids; Cell Line; CHO Cells; Cricetinae; Electrophysiology; Female; Humans; Imines; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Transient Receptor Potential Channels; TRPA1 Cation Channel

2011
Safety assessment of potential food ingredients in canine hepatocytes.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2015, Volume: 78

    Topics: Acetaminophen; Acrolein; Aflatoxin B1; Animal Feed; Animals; Cell Line; Cell Survival; Dogs; Down-Regulation; Eugenol; Food Analysis; Food Safety; Hepatocytes; Humans; Lethal Dose 50; Oils, Volatile; Plant Extracts; Plant Oils; Plant Roots; Rats; Terpenes; Thymol; Up-Regulation; Xylitol; Zingiber officinale

2015
Acrolein, a highly toxic aldehyde generated under oxidative stress in vivo, aggravates the mouse liver damage after acetaminophen overdose.
    Biomedical research (Tokyo, Japan), 2014, Volume: 35, Issue:6

    Topics: Acetaminophen; Acetylcysteine; Acrolein; Animals; Blotting, Western; Cell Culture Techniques; Chemical and Drug Induced Liver Injury; Drug Overdose; Liver; Mesna; Mice; Mice, Inbred C57BL; Oxidative Stress; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction

2014
TRPA1 mediates the hypothermic action of acetaminophen.
    Scientific reports, 2015, Jul-31, Volume: 5

    Topics: Acetaminophen; Acrolein; Animals; Antipyretics; Benzoquinones; Diterpenes; Female; Hypothermia; Hypothermia, Induced; Imines; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice, Inbred C57BL; Mice, Mutant Strains; Sensory Receptor Cells; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels

2015
Acrolein scavengers, cysteamine and N-benzylhydroxylamine, reduces the mouse liver damage after acetaminophen overdose.
    The Journal of veterinary medical science, 2017, Jan-10, Volume: 78, Issue:12

    Topics: Acetaminophen; Acrolein; Animals; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; Cysteamine; Drug Overdose; Humans; Hydroxylamines; Liver; Mice; Mice, Inbred C57BL; Oxidative Stress; Reactive Oxygen Species

2017