Page last updated: 2024-08-18

acrolein and 4-hydroxy-2-nonenal

acrolein has been researched along with 4-hydroxy-2-nonenal in 81 studies

Research

Studies (81)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (2.47)	18.7374
1990's	13 (16.05)	18.2507
2000's	32 (39.51)	29.6817
2010's	32 (39.51)	24.3611
2020's	2 (2.47)	2.80

Authors

Authors	Studies
Baraldi, PG; Geppetti, P; Materazzi, S; Preti, D	1
Benamira, M; Marnett, LJ	1
Dennis, KJ; Shibamoto, T	1
Ardlie, NG; Bartlett, MR; Jenkin, LA; McGuiness, JA; Selley, ML	1
Amoruso, MA; Goldstein, BD; Lawrie, NJ; Ryer-Powder, J; Witz, G	1
Marnett, LJ	1
Chung, FL; Li, D; Nath, RG; Randerath, K	1
Miyake, T; Shibamoto, T	1
Deck, LM; Gomez, MS; Gonzales, DM; Hunsaker, LA; Royer, RE; Vander Jagt, DL; Vander Jagt, TJ	1
Federici, G; Lo Bello, M; Ploemen, JP; van Bladeren, PJ; van Iersel, ML	1
Awasthi, S; Boor, PJ; He, NG; Singhal, SS; Trent, MB	1
Kroll, DJ; Luckey, SW; Petersen, DR; Tjalkens, RB	2
Calingasan, NY; Gibson, GE; Uchida, K	1
Hayakari, M; Igarashi, Y; Koike, Y; Kumano, T; Satoh, K; Takahata, T; Toyokuni, S; Tsuchida, S; Uchida, K; Yamada, S	1
Uchida, K	1
Asayama, K; Hirano, A; Horiuchi, S; Jono, T; Kato, S; Kobayashi, M; Miyata, S; Nagai, R; Sasaki, S; Shibata, N	1
Bielicki, JK; Forte, TM; Knoff, LJ; Tribble, DL	1
Ishibashi, A; Shigematsu, T; Tajima, S; Tanaka, N; Uchida, K	1
Albano, E; Cipriani, V; Day, CP; Moretti, M; Mottaran, E; Rigamonti, C; Rolla, R; Sartori, M; Stewart, SF; Vay, D; Vidali, M	1
Bucci, TJ; Chou, MW; Fu, PP; Kadlubar, FF; Samokyszyn, VM; Von Tungeln, LS; Yi, P	1
Kurtz, AJ; Lloyd, RS	1
Nguyen, E; Picklo, MJ	1
Butterfield, DA; Castegna, A; Lauderback, CM; Mohmmad-Abdul, H	1
Campochiaro, PA; Dong, A; Peng, YW; Petters, RM; Shen, J; Wong, F; Yang, X	1
Lovell, MA; Lynn, BC; Williams, TI	1
Lovell, MA; Lynn, BC; Markesbery, WR; Williams, TI	1
Luo, J; Shi, R; Uchida, K	1
Finkelstein, EI; Hristova, M; Koot, CW; Ruben, J; van der Vliet, A	1
Brennan, ML; Hazen, SL; Heinecke, JW; Penn, MS; Spitz, DR; Topol, EJ; Unzek, S; Vasilyev, N; Williams, T; Zhou, X	1
Audesirk, G; Cabell, L; Phansalkar, K; Pugazhenthi, S; West, A	1
Aldini, G; Beretta, G; Carini, M; Facino, RM	1
Kawaguchi-Niida, M; Kobayashi, M; Morikawa, S; Sawada, T; Shibata, N; Uchida, K; Yamamoto, T	1
Kovacic, P	1
Lovell, MA; Markesbery, WR; Roberts, KN; Scheff, SW; Shao, C	1
Aldini, G; Carini, M; Orioli, M	1
Elbaz, M; Escargueil-Blanc, I; Negre-Salvayre, A; Salvayre, R; Uchida, K; Vindis, C	1
Han, B; Maier, CS; Stevens, JF	1
Aiuchi, T; Itabe, H; Kato, R; Masuda, Y; Obama, T; Takahashi, K	1
Andrè, E; Basbaum, AI; Bautista, DM; Bunnett, NW; Campi, B; Cottrell, GS; Gatti, R; Geppetti, P; Imamachi, N; Julius, D; Materazzi, S; Nassini, R; Patacchini, R; Siemens, J; Trevisani, M	1
Go, YM; Halvey, PJ; Hansen, JM; Jones, DP; Pohl, J; Reed, M	1
Barber, DS; Gavin, T; LoPachin, RM	1
Ansari, MA; Keller, JN; Scheff, SW	1
Gavin, T; Geohagen, BC; Lopachin, RM	1
Harris, TM; Kozekov, ID; Lloyd, RS; Minko, IG; Rizzo, CJ; Stone, MP	1
Jia, Z; Li, Y; Misra, HP; Zhu, H	1
Barber, DS; Gavin, T; LoPachin, RM; Petersen, DR	1
Chen, F; Chen, J; Cheng, KW; Sze, KH; Tang, YS; Wang, M; Wu, JJ; Zhang, S; Zheng, ZP; Zhu, Q	1
Bradley, MA; Lovell, MA; Markesbery, WR	1
Ambrozova, G; Lojek, A; Pekarova, M	1
Alas, GR; Harris, CM; Harris, TM; Kozekov, ID; Rizzo, CJ; Turesky, RJ	1
Dolla, A; Gauthier, C; Iovanna, J; Lesgards, JF; Stocker, P; Vidal, N	1
Baba, SP; Bhatnagar, A; Hellmann, J; Srivastava, S	1
Bron, R; Bunnett, NW; Cattaruzza, F; Chiu, JV; Furness, JB; Gai, G; Grady, EF; Kuo, YM; Pelayo, JC; Poole, DP	1
Akiyama, M; Hattori, K; Hirao, T; Kuwahara, T; Ogura, Y; Okamoto, K; Okawa, S; Tagami, H; Tajima, S; Takahashi, M; Yamada, Y	1
Ellis, EM; Ferrari, M; Li, D	1
Rodríguez-Zavala, JS; Yoval-Sánchez, B	1
Epperson, LE; Fritz, KS; Galligan, JJ; Hunter, LE; Petersen, DR; Smathers, RL	1
Mano, J	1
Abuladze, N; Bragin, A; Cascio, D; Damoiseaux, R; Faull, K; Pushkin, A; Schibler, MJ; Tsirulnikov, K	1
Cavaillé, JP; Peiretti, F; Poggi, M; Stocker, P; Vidal, N	1
Aitken, RJ; Baker, MA; De Iuliis, GN; McClymont, S; Mitchell, LA; Whiting, S	1
Gasparovic, AC; Jaganjac, M; Mihaljevic, B; Sunjic, SB; Zarkovic, N	1
Chapman, H; Jalava, N; Koivisto, A; Korjamo, T; Lindstedt, K; Pertovaara, A; Saarnilehto, M	1
Aldini, G; Altomare, A; Bertoletti, L; Carini, M; Colombo, R; Colzani, M; De Lorenzi, E; Marchese, L; Regazzoni, L; Vistoli, G	1
Prokai, L; Prokai-Tatrai, K; Szarka, S	1
Aitken, RJ; Lord, T; Martin, JH	1
Bhatnagar, A; Kapoor, A; Singh, M	1
Ansari, NH; Ayadi, AE; Enkhbaatar, P; Finnerty, CC; Goswamy, J; Herndon, DN; Mifflin, R; Papaconstantinou, J; Sousse, L; Wang, CZ	1
Cai, C; Cao, D; Cao, Y; Chung, FL; Huang, D; Liao, DF; Liu, J; Ma, J; Pan, J; Yan, R; Zhong, L; Zu, X	1
Ameenuddin, S; Citron, BA; Festoff, BW; SantaCruz, K; Suo, WZ; Uchida, K	1
Hu, T; Jia, ZX; Tie, C; Zhang, JL	1
Bastos, LCS; de Almeida Costa, EA; Pereira, PAP	1
Cebak, JE; Hall, ED; Hill, RL; Singh, IN; Wang, JA	1
Bresgen, N; Eckl, PM	1
Pitt, AR; Sousa, BC; Spickett, CM	1
Aitken, RJ; Gibb, Z; Hall, SE; Nixon, B; Smith, ND	1
Chen, Y; Liu, B; Liu, W; Wang, J; Wang, W; Xu, F; Zhai, X; Zhang, R; Zhang, Z; Zheng, W	1
Gęgotek, A; Skrzydlewska, E	1
Chen, Y; Knaack, DA; Powers, HR; Sahoo, D; Schill, DJ; Schill, RL; Silverstein, RL; Yang, M	1
Fujii, H; Fujiya, N; Mano, J; Matsuoka, Y; Sakai, K; Sugimoto, K	1

Reviews

12 review(s) available for acrolein and 4-hydroxy-2-nonenal

Article	Year
Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents. Journal of medicinal chemistry, 2010, Jul-22, Volume: 53, Issue:14 Topics: Analgesics; Animals; Anti-Inflammatory Agents; Asthma; Humans; Ion Channel Gating; Neurons; Pain; Peripheral Nervous System Diseases; Pulmonary Disease, Chronic Obstructive; Transient Receptor Potential Channels	2010
DNA adducts of alpha,beta-unsaturated aldehydes and dicarbonyl compounds. IARC scientific publications, 1994, Issue:125 Topics: Acrolein; Aldehydes; Animals; Base Sequence; DNA; DNA Adducts; Malondialdehyde; Molecular Sequence Data; Pyruvaldehyde; Structure-Activity Relationship	1994
Endogenous production of DNA adducts. Regulatory toxicology and pharmacology : RTP, 1996, Volume: 23, Issue:1 Pt 1 Topics: Acrolein; Aging; Aldehydes; Animals; Carcinogens; Cross-Linking Reagents; DNA Adducts; Humans; Liver; Malondialdehyde; Mice; Mutation; Oxidation-Reduction; Rats; Structure-Activity Relationship	1996
Current status of acrolein as a lipid peroxidation product. Trends in cardiovascular medicine, 1999, Volume: 9, Issue:5 Topics: Acrolein; Air Pollutants; Aldehydes; Alzheimer Disease; Arteriosclerosis; Cross-Linking Reagents; Fatty Acids, Unsaturated; Glyoxal; Humans; Lipid Peroxidation; Lipid Peroxides; Lysine; Malondialdehyde; Oxidative Stress	1999
Molecular mechanisms of the conjugated alpha,beta-unsaturated carbonyl derivatives: relevance to neurotoxicity and neurodegenerative diseases. Toxicological sciences : an official journal of the Society of Toxicology, 2008, Volume: 104, Issue:2 Topics: Acrolein; Acrylamide; Aldehydes; Alzheimer Disease; Animals; Brain; Disease Models, Animal; DNA Adducts; DNA Damage; Humans; Neurotoxicity Syndromes	2008
Chemistry and biology of DNA containing 1,N(2)-deoxyguanosine adducts of the alpha,beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal. Chemical research in toxicology, 2009, Volume: 22, Issue:5 Topics: Acrolein; Aldehydes; Base Sequence; Deoxyguanosine; DNA Adducts; DNA Repair; Mutagenesis; Oligodeoxyribonucleotides	2009
Molecular mechanisms of 4-hydroxy-2-nonenal and acrolein toxicity: nucleophilic targets and adduct formation. Chemical research in toxicology, 2009, Volume: 22, Issue:9 Topics: Acrolein; Aldehydes; Cross-Linking Reagents; Kinetics; Oxidative Stress; Proteomics; Quantum Theory	2009
Reactive carbonyl species: their production from lipid peroxides, action in environmental stress, and the detoxification mechanism. Plant physiology and biochemistry : PPB, 2012, Volume: 59 Topics: Acrolein; Aldehydes; Chloroplasts; Ketones; Lipid Peroxides; Mitochondria; Oxidative Stress; Photosystem II Protein Complex; Plant Proteins; Plants; Protein Carbonylation; Reactive Oxygen Species; Stress, Physiological	2012
TRPA1: a transducer and amplifier of pain and inflammation. Basic & clinical pharmacology & toxicology, 2014, Volume: 114, Issue:1 Topics: Acetanilides; Acrolein; Aldehydes; Animals; Ankyrins; Humans; Inflammation; Mustard Plant; Oximes; Pain; Plant Oils; Purines; Spinal Cord; Transient Receptor Potential Channels	2014
Genotoxicity of lipid oxidation compounds. Free radical biology & medicine, 2017, Volume: 111 Topics: Acrolein; Aldehydes; Animals; Cells, Cultured; CHO Cells; Cricetulus; Epigenesis, Genetic; Epithelial Cells; Fibroblasts; Histone Deacetylases; Humans; Lipid Peroxidation; Lymphocytes; Mutagens; Oxysterols; Salmonella typhimurium	2017
Chemistry and analysis of HNE and other prominent carbonyl-containing lipid oxidation compounds. Free radical biology & medicine, 2017, Volume: 111 Topics: Acrolein; Aldehydes; Animals; Humans; Isoprostanes; Lactoglobulins; Lipid Peroxidation; Oxidative Stress; Protein Processing, Post-Translational	2017
Biological effect of protein modifications by lipid peroxidation products. Chemistry and physics of lipids, 2019, Volume: 221 Topics: Acrolein; Aldehydes; Animals; Humans; Isoprostanes; Lipid Peroxidation; Malondialdehyde; Proteins	2019

Trials

1 trial(s) available for acrolein and 4-hydroxy-2-nonenal

Article	Year
Electrophilic aldehydes generated by sperm metabolism activate mitochondrial reactive oxygen species generation and apoptosis by targeting succinate dehydrogenase. The Journal of biological chemistry, 2012, Sep-21, Volume: 287, Issue:39 Topics: Acrolein; Aldehydes; Apoptosis; DNA Adducts; DNA Breaks; Humans; Male; Mitochondria; Spermatozoa; Succinate Dehydrogenase; Superoxides	2012

Other Studies

68 other study(ies) available for acrolein and 4-hydroxy-2-nonenal

Article	Year
The lipid peroxidation product 4-hydroxynonenal is a potent inducer of the SOS response. Mutation research, 1992, Volume: 293, Issue:1 Topics: Acrolein; Aldehydes; Lipid Peroxidation; Malondialdehyde; Mutagens; Operon; Salmonella typhimurium; SOS Response, Genetics	1992
Gas chromatographic analysis of reactive carbonyl compounds formed from lipids upon UV-irradiation. Lipids, 1990, Volume: 25, Issue:8 Topics: Acetaldehyde; Acrolein; Aldehydes; Arachidonic Acid; Arachidonic Acids; Chromatography, Gas; Formaldehyde; Gas Chromatography-Mass Spectrometry; Linoleic Acid; Linoleic Acids; Linolenic Acids; Lipid Peroxidation; Lipids; Malondialdehyde; Monomethylhydrazine; Squalene; Ultraviolet Rays	1990
Effect of 4-hydroxy-2,3-trans-nonenal on platelet function. Thrombosis and haemostasis, 1988, Apr-08, Volume: 59, Issue:2 Topics: Acrolein; Adult; Aldehydes; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Humans; In Vitro Techniques; Platelet Aggregation; Thromboxane B2	1988
Effects of alpha, beta-unsaturated aldehydes on macrophage and neutrophil membrane function, fluidity and sulfhydryl status. Basic life sciences, 1988, Volume: 49 Topics: Acrolein; Aldehydes; Cell Membrane; Humans; In Vitro Techniques; Macrophages; Membrane Fluidity; Neutrophils; Sulfhydryl Compounds	1988
Simultaneous determination of acrolein, malonaldehyde and 4-hydroxy-2-nonenal produced from lipids oxidized with Fenton's reagent. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1996, Volume: 34, Issue:10 Topics: Acrolein; Aldehydes; Arachidonic Acids; Chromatography, Gas; Cod Liver Oil; Cross-Linking Reagents; Hydrogen Peroxide; Iron; Linoleic Acids; Linolenic Acids; Lipid Peroxidation; Malondialdehyde; Oxidation-Reduction; Reference Standards	1996
Inactivation of glutathione reductase by 4-hydroxynonenal and other endogenous aldehydes. Biochemical pharmacology, 1997, Apr-25, Volume: 53, Issue:8 Topics: Acrolein; Aldehydes; Amino Acids; Deoxyglucose; Enzyme Activation; Glutathione Reductase; Ketoses; Pyruvaldehyde; Spectrometry, Fluorescence	1997
Interactions of alpha, beta-unsaturated aldehydes and ketones with human glutathione S-transferase P1-1. Chemico-biological interactions, 1997, Dec-12, Volume: 108, Issue:1-2 Topics: Acrolein; Aldehydes; Curcumin; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Ethacrynic Acid; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Isoenzymes; Ketones; Mutagenesis, Site-Directed	1997
The role of glutathione S-transferases as a defense against reactive electrophiles in the blood vessel wall. Toxicology and applied pharmacology, 1998, Volume: 152, Issue:1 Topics: Acrolein; Aldehydes; Allylamine; Animals; Animals, Newborn; Blotting, Western; Cell Survival; Cells, Cultured; Dinitrochlorobenzene; Dose-Response Relationship, Drug; Drug Interactions; Glutathione Transferase; Inhibitory Concentration 50; Isoenzymes; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Sulfasalazine	1998
Alpha,beta-unsaturated aldehydes increase glutathione S-transferase mRNA and protein: correlation with activation of the antioxidant response element. Archives of biochemistry and biophysics, 1998, Nov-01, Volume: 359, Issue:1 Topics: Acrolein; Aldehydes; Animals; Antioxidants; Blotting, Northern; Blotting, Western; Carcinoma, Hepatocellular; Cross-Linking Reagents; Enzyme Activation; Ethacrynic Acid; Glutathione Transferase; Rats; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Transfection; Tumor Cells, Cultured	1998
Protein-bound acrolein: a novel marker of oxidative stress in Alzheimer's disease. Journal of neurochemistry, 1999, Volume: 72, Issue:2 Topics: Acrolein; Adult; Aged; Aldehydes; Alzheimer Disease; Antibody Specificity; Biomarkers; Cysteine Proteinase Inhibitors; Cytoskeleton; Female; Humans; Lipid Peroxidation; Male; Middle Aged; Nerve Degeneration; Neurofibrillary Tangles; Neurons; Oxidative Stress	1999
A 1-hour enzyme-linked immunosorbent assay for quantitation of acrolein- and hydroxynonenal-modified proteins by epitope-bound casein matrix method. Analytical biochemistry, 1999, Jun-01, Volume: 270, Issue:2 Topics: Acrolein; Aldehydes; Animals; Antibodies, Monoclonal; Caseins; Cattle; Enzyme-Linked Immunosorbent Assay; Epitopes; Humans; Immunochemistry; Ovalbumin; Proteins; Rats	1999
Alpha, beta-unsaturated aldehydes mediate inducible expression of glutathione S-transferase in hepatoma cells through activation of the antioxidant response element (ARE). Advances in experimental medicine and biology, 1999, Volume: 463 Topics: Acrolein; Aldehydes; Animals; Antioxidants; Base Sequence; Carcinoma, Hepatocellular; Gene Expression Regulation, Enzymologic; Glutathione Transferase; Isoenzymes; Molecular Sequence Data; Rats; Response Elements; Tumor Cells, Cultured	1999
Nonoxidative protein glycation is implicated in familial amyotrophic lateral sclerosis with superoxide dismutase-1 mutation. Acta neuropathologica, 2000, Volume: 100, Issue:3 Topics: 8-Hydroxy-2'-Deoxyguanosine; Acrolein; Adult; Aged; Aldehydes; Amyotrophic Lateral Sclerosis; Arginine; Deoxyguanosine; Glycosylation; Humans; Imidazoles; Lipid Peroxidation; Lysine; Male; Middle Aged; Motor Neurons; Oxidative Stress; Spinal Cord; Superoxide Dismutase	2000
Relative sensitivities of plasma lecithin:cholesterol acyltransferase, platelet-activating factor acetylhydrolase, and paraoxonase to in vitro gas-phase cigarette smoke exposure. Atherosclerosis, 2001, Volume: 155, Issue:1 Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acrolein; Aldehydes; Aryldialkylphosphatase; Dithionitrobenzoic Acid; Dose-Response Relationship, Drug; Esterases; Humans; In Vitro Techniques; Nicotiana; Phosphatidylcholine-Sterol O-Acyltransferase; Phospholipases A; Plants, Toxic; Smoke; Sulfhydryl Reagents	2001
Immunohistochemical detection of lipid peroxidation products, protein-bound acrolein and 4-hydroxynonenal protein adducts, in actinic elastosis of photodamaged skin. Archives of dermatological research, 2001, Volume: 293, Issue:7 Topics: Acrolein; Aged; Aged, 80 and over; Aldehydes; Elastic Tissue; Female; Humans; Immunohistochemistry; Lipid Peroxides; Male; Middle Aged; Photosensitivity Disorders; Skin Aging; Thyroid Function Tests; Tissue Distribution	2001
Lipid peroxidation contributes to immune reactions associated with alcoholic liver disease. Free radical biology & medicine, 2002, Jan-01, Volume: 32, Issue:1 Topics: Acrolein; Adult; Aged; Aldehydes; Arachidonic Acid; Ethanol; Female; Humans; Immunoglobulin G; Linoleic Acid; Lipid Peroxidation; Liver Diseases, Alcoholic; Male; Malondialdehyde; Middle Aged; Oxidation-Reduction; Oxidative Stress; Serum Albumin	2002
Tumorigenicity of chloral hydrate, trichloroacetic acid, trichloroethanol, malondialdehyde, 4-hydroxy-2-nonenal, crotonaldehyde, and acrolein in the B6C3F(1) neonatal mouse. Cancer letters, 2002, Nov-08, Volume: 185, Issue:1 Topics: Acrolein; Aldehydes; Animals; Animals, Newborn; Carcinogenicity Tests; Carcinogens; Chloral Hydrate; Chromatography, High Pressure Liquid; Crosses, Genetic; DNA; DNA Adducts; Electrochemistry; Ethylene Chlorohydrin; Female; Lipid Peroxidation; Liver; Liver Neoplasms, Experimental; Male; Malondialdehyde; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Microsomes, Liver; Phosphorus Radioisotopes; Trichloroacetic Acid	2002
1,N2-deoxyguanosine adducts of acrolein, crotonaldehyde, and trans-4-hydroxynonenal cross-link to peptides via Schiff base linkage. The Journal of biological chemistry, 2003, Feb-21, Volume: 278, Issue:8 Topics: Acrolein; Aldehydes; Amino Acid Sequence; Cross-Linking Reagents; Deoxyguanosine; DNA Adducts; Kinetics; Models, Molecular; Molecular Structure; Oligopeptides; Schiff Bases	2003
Inhibition of succinic semialdehyde dehydrogenase activity by alkenal products of lipid peroxidation. Biochimica et biophysica acta, 2003, Jan-20, Volume: 1637, Issue:1 Topics: Acrolein; Aldehyde Oxidoreductases; Aldehydes; Animals; Brain Chemistry; gamma-Aminobutyric Acid; Glutathione; Lipid Peroxidation; Male; Mitochondria; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Succinate-Semialdehyde Dehydrogenase	2003
Modulation of phospholipid asymmetry in synaptosomal membranes by the lipid peroxidation products, 4-hydroxynonenal and acrolein: implications for Alzheimer's disease. Brain research, 2004, Apr-09, Volume: 1004, Issue:1-2 Topics: Acrolein; Aldehydes; Alzheimer Disease; Animals; Carrier Proteins; Cell Membrane; Cerebral Cortex; Gerbillinae; Lipid Peroxidation; Membrane Proteins; Phospholipid Transfer Proteins; Phospholipids; Synaptosomes	2004
Oxidative damage is a potential cause of cone cell death in retinitis pigmentosa. Journal of cellular physiology, 2005, Volume: 203, Issue:3 Topics: Acrolein; Aldehydes; Animals; Animals, Genetically Modified; Biomarkers; Cell Communication; Cell Death; Cell Survival; Disease Models, Animal; DNA Damage; Hyperoxia; Immunohistochemistry; Lipid Peroxidation; Nerve Degeneration; Oxidative Stress; Retinal Cone Photoreceptor Cells; Retinal Rod Photoreceptor Cells; Retinitis Pigmentosa; Sus scrofa	2005
Analysis of derivatized biogenic aldehydes by LC tandem mass spectrometry. Analytical chemistry, 2005, May-15, Volume: 77, Issue:10 Topics: Acrolein; Aldehydes; Alzheimer Disease; Biomarkers; Chromatography, Liquid; Humans; Lipid Peroxidation; Tandem Mass Spectrometry; Tissue Distribution	2005
Increased levels of 4-hydroxynonenal and acrolein, neurotoxic markers of lipid peroxidation, in the brain in Mild Cognitive Impairment and early Alzheimer's disease. Neurobiology of aging, 2006, Volume: 27, Issue:8 Topics: Acrolein; Aged, 80 and over; Aldehydes; Alzheimer Disease; Biomarkers; Brain; Cognition Disorders; Female; Humans; Lipid Peroxidation; Male; Tissue Distribution	2006
Accumulation of acrolein-protein adducts after traumatic spinal cord injury. Neurochemical research, 2005, Volume: 30, Issue:3 Topics: Acrolein; Aldehydes; Animals; Blotting, Western; Densitometry; Female; Guinea Pigs; Immunohistochemistry; Lipid Peroxidation; Protein Binding; Proteins; Spinal Cord Injuries	2005
Regulation of constitutive neutrophil apoptosis by the alpha,beta-unsaturated aldehydes acrolein and 4-hydroxynonenal. American journal of physiology. Lung cellular and molecular physiology, 2005, Volume: 289, Issue:6 Topics: Acrolein; Air Pollutants; Aldehydes; Apoptosis; Caspases; Cells, Cultured; Cysteine Proteinase Inhibitors; Cytochromes c; Enzyme Activation; Glutathione; Humans; Lipid Peroxidation; Mitochondria; Necrosis; Neutrophils; Phosphatidylserines	2005
Myeloperoxidase-generated oxidants modulate left ventricular remodeling but not infarct size after myocardial infarction. Circulation, 2005, Nov-01, Volume: 112, Issue:18 Topics: Acrolein; Aldehydes; Animals; Aorta; Cattle; Cell Line; Cell Survival; Cells, Cultured; Formaldehyde; Glutathione; Glutathione Disulfide; Humans; Hydrogen Peroxide; Muscle, Smooth, Vascular; Myocardial Infarction; Neutrophils; Peroxidase; Pulmonary Artery; Ventricular Remodeling	2005
Differential regulation of c-jun and CREB by acrolein and 4-hydroxynonenal. Free radical biology & medicine, 2006, Jan-01, Volume: 40, Issue:1 Topics: Acrolein; Adenoviridae; Aldehydes; Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Caspase 3; Caspases; Cyclic AMP Response Element-Binding Protein; Enzyme Activation; Female; Hippocampus; Humans; Lipid Peroxidation; Neuroblastoma; Neurons; Phosphorylation; Pregnancy; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley	2006
Carnosine and related dipeptides as quenchers of reactive carbonyl species: from structural studies to therapeutic perspectives. BioFactors (Oxford, England), 2005, Volume: 24, Issue:1-4 Topics: Acrolein; Aldehydes; Animals; Anserine; Carnosine; Chromatography, Liquid; Dipeptides; Histidine; Muscle, Skeletal; Oxidation-Reduction; Rats; Spectrometry, Mass, Electrospray Ionization	2005
Crotonaldehyde accumulates in glial cells of Alzheimer's disease brain. Acta neuropathologica, 2006, Volume: 111, Issue:5 Topics: Acrolein; Aged; Aged, 80 and over; Aldehydes; Alzheimer Disease; Astrocytes; Brain; Female; Humans; Lipid Peroxidation; Male; Middle Aged; Neuroglia; Oxidative Stress	2006
Novel electrochemical approach to enhanced toxicity of 4-oxo-2-nonenal vs. 4-hydroxy-2-nonenal (role of imine): oxidative stress and therapeutic modalities. Medical hypotheses, 2006, Volume: 67, Issue:1 Topics: Acrolein; Aldehydes; Biochemistry; Electrochemistry; Electron Transport; Imines; Models, Biological; Models, Chemical; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species	2006
Oxidative stress in head trauma in aging. Free radical biology & medicine, 2006, Jul-01, Volume: 41, Issue:1 Topics: Acrolein; Age Factors; Aldehydes; Animals; Antioxidants; Cerebral Cortex; Craniocerebral Trauma; Glutathione Reductase; Hippocampus; Lipid Peroxidation; Male; Oxidative Stress; Rats; Rats, Inbred F344; Superoxide Dismutase	2006
Alpha,beta-unsaturated aldehydes adducts to actin and albumin as potential biomarkers of carbonylation damage. Redox report : communications in free radical research, 2007, Volume: 12, Issue:1 Topics: Acrolein; Actins; Aldehydes; Chromatography, Liquid; Humans; Lipid Peroxidation; Mass Spectrometry; Serum Albumin	2007
Lipid oxidation products and oxidized low-density lipoproteins impair platelet-derived growth factor receptor activity in smooth muscle cells: implication in atherosclerosis. Redox report : communications in free radical research, 2007, Volume: 12, Issue:1 Topics: Acrolein; Aldehydes; Animals; Atherosclerosis; Lipid Peroxidation; Lipoproteins, LDL; Muscle, Smooth, Vascular; Oxidative Stress; Phosphorylation; Receptor, Platelet-Derived Growth Factor beta	2007
Design, synthesis, and application of a hydrazide-functionalized isotope-coded affinity tag for the quantification of oxylipid-protein conjugates. Analytical chemistry, 2007, May-01, Volume: 79, Issue:9 Topics: Acrolein; Aldehydes; Alkenes; Animals; Carbon Isotopes; Chromatography, High Pressure Liquid; Hydrazines; Lipid Peroxidation; Lipids; Mitochondria, Heart; Mitochondrial Proteins; Molecular Probes; Molecular Structure; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2007
Analysis of modified apolipoprotein B-100 structures formed in oxidized low-density lipoprotein using LC-MS/MS. Proteomics, 2007, Volume: 7, Issue:13 Topics: Acrolein; Aldehydes; Amino Acid Sequence; Apolipoprotein B-100; Chloroform; Chromatography, Liquid; Copper Sulfate; Cysteine; Electrophoresis, Polyacrylamide Gel; Histidine; Humans; Kynurenine; Lipoproteins, LDL; Lysine; Molecular Sequence Data; Oxidation-Reduction; Peptide Fragments; Polyvinyls; Tandem Mass Spectrometry; Trypsin; Tryptophan	2007
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1. Proceedings of the National Academy of Sciences of the United States of America, 2007, Aug-14, Volume: 104, Issue:33 Topics: Acrolein; Aldehydes; Ankyrins; Calcium Channels; Cell Line; Cloning, Molecular; Humans; Inflammation; Pain; Patch-Clamp Techniques; TRPA1 Cation Channel; TRPC Cation Channels	2007
Reactive aldehyde modification of thioredoxin-1 activates early steps of inflammation and cell adhesion. The American journal of pathology, 2007, Volume: 171, Issue:5 Topics: Acrolein; Aldehydes; Amino Acid Sequence; Animals; Aorta; Atherosclerosis; Cattle; Cell Adhesion; Cell Line; Endothelial Cells; Glutathione; Humans; Inflammation; JNK Mitogen-Activated Protein Kinases; Molecular Sequence Data; Monocytes; NF-kappa B; Oxidation-Reduction; Phosphorylation; Reactive Oxygen Species; Thioredoxins	2007
Protective effect of Pycnogenol in human neuroblastoma SH-SY5Y cells following acrolein-induced cytotoxicity. Free radical biology & medicine, 2008, Dec-01, Volume: 45, Issue:11 Topics: Acrolein; Aldehydes; Analysis of Variance; Blotting, Western; Cell Line, Tumor; Cell Survival; Cytotoxins; Flavonoids; Free Radicals; Glutathione; Humans; Lipid Peroxidation; Luminescence; NADPH Oxidases; Neuroblastoma; Neurons; Neuroprotective Agents; Oxidative Stress; Plant Extracts; Protein Carbonylation; Tyrosine	2008
Synaptosomal toxicity and nucleophilic targets of 4-hydroxy-2-nonenal. Toxicological sciences : an official journal of the Society of Toxicology, 2009, Volume: 107, Issue:1 Topics: Acetylcysteine; Acrolein; Aldehydes; Amino Acids; Animals; Biological Transport; Carnosine; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Male; Mechanics; Nonlinear Dynamics; Oxidative Stress; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Regression Analysis; Sulfhydryl Compounds; Synaptosomes; Transport Vesicles; Tritium	2009
Cruciferous nutraceutical 3H-1,2-dithiole-3-thione protects human primary astrocytes against neurocytotoxicity elicited by MPTP, MPP(+), 6-OHDA, HNE and acrolein. Neurochemical research, 2009, Volume: 34, Issue:11 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Acrolein; Aldehydes; Astrocytes; Brassicaceae; Cells, Cultured; Glutathione; Glutathione Reductase; Humans; NAD(P)H Dehydrogenase (Quinone); Oxidants; Oxidopamine; RNA, Messenger; Thiones; Thiophenes	2009
Natural polyphenols as direct trapping agents of lipid peroxidation-derived acrolein and 4-hydroxy-trans-2-nonenal. Chemical research in toxicology, 2009, Volume: 22, Issue:10 Topics: Acrolein; Aldehydes; Chromatography, Liquid; Cross-Linking Reagents; Flavonoids; Lipid Peroxidation; Molecular Conformation; Phenols; Phloretin; Polyphenols; Tandem Mass Spectrometry	2009
Increased levels of 4-hydroxynonenal and acrolein in the brain in preclinical Alzheimer disease. Free radical biology & medicine, 2010, Jun-15, Volume: 48, Issue:12 Topics: Acrolein; Aged, 80 and over; Aldehydes; Alzheimer Disease; Brain; Brain Chemistry; Female; Gas Chromatography-Mass Spectrometry; Humans; Immunoblotting; Immunohistochemistry; Male	2010
The effect of lipid peroxidation products on reactive oxygen species formation and nitric oxide production in lipopolysaccharide-stimulated RAW 264.7 macrophages. Toxicology in vitro : an international journal published in association with BIBRA, 2011, Volume: 25, Issue:1 Topics: Acrolein; Aldehydes; Animals; Cell Line, Transformed; Cell Survival; Down-Regulation; Free Radical Scavengers; Lipid Peroxidation; Lipopolysaccharides; Macrophage Activation; Macrophages; Malondialdehyde; Mice; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Osmolar Concentration; Reactive Oxygen Species; Time Factors	2011
Formation of deoxyguanosine cross-links from calf thymus DNA treated with acrolein and 4-hydroxy-2-nonenal. Chemical research in toxicology, 2010, Nov-15, Volume: 23, Issue:11 Topics: Acrolein; Aldehydes; Animals; Cattle; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA; DNA Adducts; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Time Factors	2010
Effect of reactive oxygen and carbonyl species on crucial cellular antioxidant enzymes. Chemico-biological interactions, 2011, Mar-15, Volume: 190, Issue:1 Topics: Acrolein; Aldehydes; Amidines; Antioxidants; Cell Line, Tumor; Glucosephosphate Dehydrogenase; Glutathione Peroxidase; Glutathione Transferase; Glyoxal; Humans; Hydrogen Peroxide; Malondialdehyde; Oxidative Stress; Oxidoreductases; Pyruvaldehyde; Reactive Oxygen Species; Superoxide Dismutase	2011
Aldose reductase (AKR1B3) regulates the accumulation of advanced glycosylation end products (AGEs) and the expression of AGE receptor (RAGE). Chemico-biological interactions, 2011, May-30, Volume: 191, Issue:1-3 Topics: Acrolein; Adipose Tissue; Aldehyde Reductase; Aldehydes; Animals; Diabetes Mellitus, Experimental; Dietary Fats; Epididymis; Gene Deletion; Gene Expression Regulation; Glycation End Products, Advanced; Kidney; Male; Mice; Obesity; Oxidation-Reduction; Receptor for Advanced Glycation End Products; Receptors, Immunologic	2011
Transient receptor potential ankyrin 1 is expressed by inhibitory motoneurons of the mouse intestine. Gastroenterology, 2011, Volume: 141, Issue:2 Topics: Acrolein; Aldehydes; Animals; Carbachol; Cecum; Colon; Duodenum; Epithelial Cells; Female; Fluorescent Antibody Technique; Ganglia; Gastric Emptying; Gastric Mucosa; Gastrointestinal Motility; Ileum; Interneurons; Intestinal Mucosa; Isothiocyanates; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Neurons; Muscle Contraction; Muscle, Smooth; Neurons, Afferent; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stomach; Substance P; Transient Receptor Potential Channels; TRPA1 Cation Channel	2011
Dermal carbonyl modification is related to the yellowish color change of photo-aged Japanese facial skin. Journal of dermatological science, 2011, Volume: 64, Issue:1 Topics: Acrolein; Aged, 80 and over; Aldehydes; Carbon; Collagen; Color; Elasticity; Face; Female; Humans; Japan; Light; Male; Middle Aged; Skin; Skin Aging	2011
Human aldo-keto reductase AKR7A2 protects against the cytotoxicity and mutagenicity of reactive aldehydes and lowers intracellular reactive oxygen species in hamster V79-4 cells. Chemico-biological interactions, 2012, Jan-05, Volume: 195, Issue:1 Topics: Acrolein; Aldehyde Reductase; Aldehydes; Animals; Caspase 3; Cell Line; Cricetinae; DNA Damage; Glutathione; Humans; Mutagenicity Tests; Oxidative Stress; Pyruvaldehyde; Reactive Oxygen Species	2012
Differences in susceptibility to inactivation of human aldehyde dehydrogenases by lipid peroxidation byproducts. Chemical research in toxicology, 2012, Mar-19, Volume: 25, Issue:3 Topics: Acrolein; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Aldehyde Dehydrogenase, Mitochondrial; Aldehydes; Amino Acid Sequence; Humans; Lipid Peroxidation; Malondialdehyde; Molecular Sequence Data; Recombinant Proteins; Retinal Dehydrogenase; Sequence Alignment	2012
Protein carbonylation in a murine model for early alcoholic liver disease. Chemical research in toxicology, 2012, May-21, Volume: 25, Issue:5 Topics: Acrolein; Aldehydes; Animals; Ethanol; Fatty Acids; Liver; Liver Diseases, Alcoholic; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Protein Carbonylation; Proteins; Proteomics; Tandem Mass Spectrometry; Thiobarbituric Acid Reactive Substances	2012
Inhibition of aminoacylase 3 protects rat brain cortex neuronal cells from the toxicity of 4-hydroxy-2-nonenal mercapturate and 4-hydroxy-2-nonenal. Toxicology and applied pharmacology, 2012, Sep-15, Volume: 263, Issue:3 Topics: Acetylation; Acetylcysteine; Acrolein; Aldehydes; Alzheimer Disease; Amidohydrolases; Aminooxyacetic Acid; Animals; Cerebral Cortex; Enzyme Inhibitors; Male; Neurons; Parkinson Disease; Rats; Rats, Wistar	2012
A nonradioisotope chemiluminescent assay for evaluation of 2-deoxyglucose uptake in 3T3-L1 adipocytes. Effect of various carbonyls species on insulin action. Biochimie, 2012, Volume: 94, Issue:12 Topics: 3T3-L1 Cells; Acrolein; Adipocytes; Aldehydes; Animals; Biological Transport; Chromans; Cytochalasin B; Deoxyglucose; Hydrogen Peroxide; Hypoglycemic Agents; Insulin; Luminescent Measurements; Mice; Pyruvaldehyde; Reproducibility of Results; Thiazolidinediones; Troglitazone	2012
Assays for the measurement of lipid peroxidation. Methods in molecular biology (Clifton, N.J.), 2013, Volume: 965 Topics: Acrolein; Aldehydes; Biomarkers; Blotting, Western; Cells, Cultured; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Intracellular Space; Lipid Peroxidation; Lipid Peroxides; Malondialdehyde; Membrane Proteins; Oxidative Stress; Signal Transduction	2013
Advanced glycation end products of beta2-microglobulin in uremic patients as determined by high resolution mass spectrometry. Journal of pharmaceutical and biomedical analysis, 2014, Volume: 91 Topics: Acrolein; Aldehydes; Arginine; beta 2-Microglobulin; Glucose; Glycation End Products, Advanced; Glyoxal; Humans; Mass Spectrometry; Pyruvaldehyde; Uremia	2014
Application of screening experimental designs to assess chromatographic isotope effect upon isotope-coded derivatization for quantitative liquid chromatography-mass spectrometry. Analytical chemistry, 2014, Jul-15, Volume: 86, Issue:14 Topics: Acrolein; Aldehydes; Animals; Carbon Isotopes; Chromatography, Liquid; Deuterium; Female; Isotope Labeling; Malondialdehyde; Mice, Inbred Strains; Nitrogen Isotopes; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Temperature	2014
Accumulation of electrophilic aldehydes during postovulatory aging of mouse oocytes causes reduced fertility, oxidative stress, and apoptosis. Biology of reproduction, 2015, Volume: 92, Issue:2 Topics: Acrolein; Aldehydes; Animals; Apoptosis; Female; Fertility; Lipid Peroxidation; Malondialdehyde; Mice; Oocytes; Ovulation; Oxidative Stress; Reactive Oxygen Species; Succinate Dehydrogenase	2015
Oxidative and reductive metabolism of lipid-peroxidation derived carbonyls. Chemico-biological interactions, 2015, Jun-05, Volume: 234 Topics: Acrolein; Alcohol Oxidoreductases; Aldehyde Dehydrogenase; Aldehyde Reductase; Aldehydes; Aldo-Keto Reductases; Glutathione; Lipid Peroxidation; Lipids; Malondialdehyde; Oxidation-Reduction; Oxidative Stress; Oxidoreductases; Protein Carbonylation; Reactive Oxygen Species	2015
Topically applied metal chelator reduces thermal injury progression in a rat model of brass comb burn. Burns : journal of the International Society for Burn Injuries, 2015, Volume: 41, Issue:8 Topics: Acrolein; Administration, Cutaneous; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Aldehyde Dehydrogenase, Mitochondrial; Aldehydes; Animals; Burns; Chelating Agents; Copper; Dimethyl Sulfoxide; Disease Models, Animal; Edetic Acid; Immunohistochemistry; Malondialdehyde; Mitochondrial Proteins; Oxidative Stress; Permeability; Rats; Retinal Dehydrogenase; Skin; Sulfones; Trauma Severity Indices; Zinc	2015
Aldo-keto reductase 1B10 protects human colon cells from DNA damage induced by electrophilic carbonyl compounds. Molecular carcinogenesis, 2017, Volume: 56, Issue:1 Topics: Acrolein; Aldehyde Reductase; Aldehydes; Aldo-Keto Reductases; Cell Line, Tumor; Colon; Colorectal Neoplasms; DNA Damage; Gene Silencing; Humans; Mutagens; Rectum	2017
Membrane lipid peroxidation in neurodegeneration: Role of thrombin and proteinase-activated receptor-1. Brain research, 2016, 07-15, Volume: 1643 Topics: Acrolein; Aldehydes; Alzheimer Disease; Animals; Cells, Cultured; Cytoplasm; Dose-Response Relationship, Drug; Humans; Lipid Peroxidation; Membrane Lipids; Mice; Motor Neurons; Parkinson Disease; Receptor, PAR-1; Thrombin	2016
Derivatization Strategy for the Comprehensive Characterization of Endogenous Fatty Aldehydes Using HPLC-Multiple Reaction Monitoring. Analytical chemistry, 2016, 08-02, Volume: 88, Issue:15 Topics: Acrolein; Aldehydes; Animals; Biomarkers; Brain; Chromatography, High Pressure Liquid; Dementia; Deuterium; Discriminant Analysis; Disease Models, Animal; Fatty Acids; Limit of Detection; Male; Principal Component Analysis; Rats; Rats, Wistar; Triazines	2016
Development, validation and application of an UFLC-DAD-ESI-MS method for determination of carbonyl compounds in soybean oil during continuous heating. Food chemistry, 2017, Mar-01, Volume: 218 Topics: Acrolein; Aldehydes; Chromatography, High Pressure Liquid; Heating; Soybean Oil; Spectrometry, Mass, Electrospray Ionization	2017
Phenelzine Protects Brain Mitochondrial Function In Vitro and In Vivo following Traumatic Brain Injury by Scavenging the Reactive Carbonyls 4-Hydroxynonenal and Acrolein Leading to Cortical Histological Neuroprotection. Journal of neurotrauma, 2017, 04-01, Volume: 34, Issue:7 Topics: Acrolein; Aldehydes; Animals; Brain Injuries, Traumatic; Cerebral Cortex; Disease Models, Animal; Male; Mitochondria; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Phenelzine; Rats; Rats, Sprague-Dawley	2017
Electrophilic aldehyde products of lipid peroxidation selectively adduct to heat shock protein 90 and arylsulfatase A in stallion spermatozoa. Biology of reproduction, 2017, 01-01, Volume: 96, Issue:1 Topics: Acrolein; Aldehyde Dehydrogenase, Mitochondrial; Aldehydes; Animals; Cerebroside-Sulfatase; Horses; HSP90 Heat-Shock Proteins; Lipid Peroxidation; Male; Malondialdehyde; Reactive Oxygen Species; Sperm Motility; Spermatozoa; Zona Pellucida	2017
Protective effect of ALDH2 against cyclophosphamide-induced acute hepatotoxicity via attenuating oxidative stress and reactive aldehydes. Biochemical and biophysical research communications, 2018, 04-30, Volume: 499, Issue:1 Topics: Acrolein; Alanine Transaminase; Aldehyde Dehydrogenase, Mitochondrial; Aldehydes; Animals; Aspartate Aminotransferases; Blood Urea Nitrogen; Chemical and Drug Induced Liver Injury; Creatinine; Cyclophosphamide; Cystatin C; Gene Expression Regulation; Kidney; L-Lactate Dehydrogenase; Liver; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Reactive Oxygen Species	2018
Modification of HDL by reactive aldehydes alters select cardioprotective functions of HDL in macrophages. The FEBS journal, 2020, Volume: 287, Issue:4 Topics: Acrolein; Aldehydes; Animals; Cell Movement; Female; Gene Expression; Interleukin-10; Interleukin-1beta; Interleukin-6; Lipoproteins, HDL; Lipoproteins, LDL; Macrophages, Peritoneal; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; NF-kappa B; Nitric Oxide Synthase Type II; Primary Cell Culture; Reactive Oxygen Species; Tumor Necrosis Factor-alpha	2020
Catechins in green tea powder (matcha) are heat-stable scavengers of acrolein, a lipid peroxide-derived reactive carbonyl species. Food chemistry, 2021, Sep-01, Volume: 355 Topics: Acrolein; Aldehydes; Catechin; Chromatography, High Pressure Liquid; Cooking; Free Radical Scavengers; Hot Temperature; Mass Spectrometry; Plant Extracts; Powders; Tea	2021