acrolein has been researched along with 2-butenal in 74 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (10.81) | 18.7374 |
| 1990's | 15 (20.27) | 18.2507 |
| 2000's | 22 (29.73) | 29.6817 |
| 2010's | 23 (31.08) | 24.3611 |
| 2020's | 6 (8.11) | 2.80 |
| Authors | Studies |
|---|---|
| Baraldi, PG; Geppetti, P; Materazzi, S; Preti, D | 1 |
| Benamira, M; Marnett, LJ | 1 |
| Chung, FL; Foiles, PG; Frank, AA; Harris, CC; Povey, AC; Wilson, VL | 1 |
| Akerkar, SA; Chung, FL; Foiles, PG; Miglietta, LM | 1 |
| Hayakawa, T; Nishikawa, H; Sakai, T | 1 |
| Cooper, KO; Witmer, CM; Witz, G | 1 |
| Amoruso, MA; Goldstein, BD; Lawrie, NJ; Ryer-Powder, J; Witz, G | 1 |
| Chung, FL; Hecht, SS; Young, R | 1 |
| Götharson, A; Högberg, J; Holmberg, B; Kronevi, T; Warholm, M | 1 |
| Bridges, RB; Haack, DG; Hsieh, L | 1 |
| Cross, CE; Halliwell, B; O'Neill, CA; van der Vliet, A | 1 |
| Marnett, LJ | 1 |
| Chung, FL; Nath, RG | 1 |
| Chen, HJ; Chung, FL; Nath, RG; Nishikawa, A; Young-Sciame, R | 1 |
| Chung, FL; Nath, RG; Ocando, JE | 1 |
| Chung, FL; Li, D; Nath, RG; Randerath, K | 1 |
| Iersel, ML; Keyzer, AE; Ploemen, JP; Schefferlie, JG; Struik, I; van Amersfoort, C; van Bladeren, PJ | 1 |
| Deck, LM; Gomez, MS; Gonzales, DM; Hunsaker, LA; Royer, RE; Vander Jagt, DL; Vander Jagt, TJ | 1 |
| Federici, G; Lo Bello, M; Ploemen, JP; van Bladeren, PJ; van Iersel, ML | 1 |
| Boerth, DW; Eder, E; Hoffman, C; Hussain, S | 1 |
| Chung, FL; Nath, RG; Ocando, JE; Zhang, L | 1 |
| Chung, FL; Fang, JL; Hemminki, K; Li, D; Yang, K | 1 |
| Hu, X; Pal, A; Singh, SV; Zimniak, P | 1 |
| Chung, FL; Pan, J | 1 |
| Bucci, TJ; Chou, MW; Fu, PP; Kadlubar, FF; Samokyszyn, VM; Von Tungeln, LS; Yi, P | 1 |
| Kurtz, AJ; Lloyd, RS | 1 |
| Harris, CM; Harris, TM; Kozekov, ID; Moseley, MS; Nechev, LV; Rizzo, CJ; Stone, MP | 1 |
| Skrzydlewska, E; Łuczaj, W | 1 |
| OWE-LARSSON, A; SKOG, E | 1 |
| Burcham, PC; Kaminskas, LM; Pyke, SM | 1 |
| Herrington, J; Sheldon, L; Whitaker, D; Zhang, JJ; Zhang, L | 1 |
| Kawaguchi-Niida, M; Kobayashi, M; Morikawa, S; Sawada, T; Shibata, N; Uchida, K; Yamamoto, T | 1 |
| Cahill, TM; Charles, MJ; Seaman, VY | 1 |
| Engl, J; Hagedorn, HW; Riedel, K; Scherer, G; Urban, M | 1 |
| Kailasam, S; Rogers, KR | 1 |
| Freed, BM; Harvey, J; Jonscher, K; Lambert, C; Li, J; Quintana, M; Reigan, P; Yang, TC | 1 |
| Adeyanju, M; Cao, D; Liu, Z; Ma, J; Yan, R; Zu, X | 1 |
| Arakawa, H; Bishop, DK; Buerstedde, JM; Gillespie, DA; Luke, AM; Nakamura, A; Nakamura, J; Ridpath, JR; Sale, JE; Sonoda, E; Swenberg, JA; Takata, M; Takeda, S; Tano, K; Watanabe, M; Yamazoe, M | 1 |
| Cabañas, B; Martín, P; Monedero, E; Salgado, MS; Tapia, A; Villanueva, F | 1 |
| Amadesi, S; Andrè, E; Baraldi, PG; Bunnett, NW; Campi, B; Civelli, M; Creminon, C; Geppetti, P; Massi, D; Materazzi, S; Nassini, R; Patacchini, R; Poole, DP; Trevisani, M; Vaksman, N | 1 |
| Liedtke, W; Simon, SA | 1 |
| Glorius, F; Hirano, K | 1 |
| Harris, TM; Kozekov, ID; Lloyd, RS; Minko, IG; Rizzo, CJ; Stone, MP | 1 |
| Hiraoka, E; Mano, J; Miyatake, F; Tamoi, M | 1 |
| Aldini, G; Carini, M; Colombo, G; Colombo, R; Dalle-Donne, I; Giustarini, D; Gornati, R; Milzani, A; Orioli, M; Rossi, R | 1 |
| Chen, HJ; Lin, WP | 1 |
| Sugimoto, Y; Yamauchi, Y | 1 |
| Liu, L; Lv, G; Song, C; Song, J; Zhao, R; Zhao, Z | 1 |
| Civelli, M; Facchinetti, F; Moretto, N; Patacchini, R; Volpi, G | 1 |
| Creus, A; Demir, E; Kaya, B; Marcos, R; Soriano, C | 1 |
| Ellis, EM; Ferrari, M; Li, D | 1 |
| Carmella, SG; Chen, JG; Chen, M; Chen, TY; Egner, PA; Fahey, JW; Groopman, JD; Hecht, SS; Jacobson, LP; Kensler, TW; Muñoz, A; Ng, D; Qian, GS; Talalay, P; Yuan, JM | 1 |
| Aoki, Y; Furuhama, A; Shiraishi, H | 1 |
| Creus, A; Demir, E; Kaya, B; Marcos, R; Turna, F | 1 |
| Ishihara, A; Kozutsumi, D; Nakajima, H; Nakamura, R; Sato, Y; Taguchi, T | 1 |
| Carmella, SG; Chen, M; Hecht, SS; Zarth, A | 1 |
| Granvogl, M | 1 |
| SKOG, E | 1 |
| Carmella, SG; Chen, M; Hecht, SS; Koh, WP; Murphy, SE; Wang, R; Yuan, JM | 1 |
| Carmella, SG; Chen, M; Haiman, CA; Hecht, SS; Le Marchand, L; Park, SL; Patel, Y; Stram, DO | 1 |
| Cui, P; Wang, Y | 1 |
| Grant, RL; Jenkins, AF | 1 |
| Carmella, SG; Hatsukami, D; Hecht, SS; Murphy, SE; Nelson, HH; Stepanov, I; Wang, R; Yuan, JM | 1 |
| Pitt, AR; Sousa, BC; Spickett, CM | 1 |
| Ho, CT; Hung, WL; Niu, YS; Suh, JH; Wang, Y | 1 |
| Dwivedi, AM; Ernstgård, L; Johanson, G; Lundström, JN | 1 |
| Farsalinos, KE; Leischow, SJ; Poulas, K; Sarri, T; Voudris, V; Yannovits, N | 1 |
| Hatai, M; Horiyama, S; Ichikawa, A; Kunitomo, M; Nakamura, K; Yoshikawa, N | 1 |
| Carmella, SG; Chen, M; Hecht, SS; Li, Y; Zhao, Y | 1 |
| Bhatnagar, A; Conklin, DJ; DeFilippis, AP; Krishnasamy, S; Lorkiewicz, P; Lynch, J; McGraw, KE; Navas-Acien, A; Rai, S; Riggs, DW; Srivastava, S; Taylor, KC; Xie, Z; Zafar, N | 1 |
| Pluym, N; Scherer, G; Scherer, M | 1 |
| Bhatnagar, A; DeJarnett, N; Hall, ME; Keith, RJ; Konkle, SL; McGraw, KE; Oshunbade, A; Rai, SN; Riggs, DW; Shimbo, D; Xie, Z | 1 |
| Cao, S; Chen, W; Liu, W; Qiu, W; Shi, D; Wang, B; Yu, L | 1 |
8 review(s) available for acrolein and 2-butenal
| Article | Year |
|---|---|
Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Asthma; Humans; Ion Channel Gating; Neurons; Pain; Peripheral Nervous System Diseases; Pulmonary Disease, Chronic Obstructive; Transient Receptor Potential Channels | 2010 |
DNA adducts of alpha,beta-unsaturated aldehydes and dicarbonyl compounds.
Topics: Acrolein; Aldehydes; Animals; Base Sequence; DNA; DNA Adducts; Malondialdehyde; Molecular Sequence Data; Pyruvaldehyde; Structure-Activity Relationship | 1994 |
Endogenous production of DNA adducts.
Topics: Acrolein; Aging; Aldehydes; Animals; Carcinogens; Cross-Linking Reagents; DNA Adducts; Humans; Liver; Malondialdehyde; Mice; Mutation; Oxidation-Reduction; Rats; Structure-Activity Relationship | 1996 |
Role of 1,N2-propanodeoxyguanosine adducts as endogenous DNA lesions in rodents and humans.
Topics: Acrolein; Aldehydes; Animals; Arachidonic Acid; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA; DNA Adducts; DNA Damage; Docosahexaenoic Acids; Fatty Acids; Glutathione; Humans; Linoleic Acid; Lipid Peroxidation; Mice; Models, Chemical; Rats | 1999 |
Nucleophilic carbenes as organocatalysts.
Topics: Acrolein; Aldehydes; Catalysis; Chemistry, Organic; Hydrocarbons; Imines; Ketones; Ligands; Methane; Models, Molecular; Molecular Conformation; Organic Chemicals; Stereoisomerism | 2007 |
Chemistry and biology of DNA containing 1,N(2)-deoxyguanosine adducts of the alpha,beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal.
Topics: Acrolein; Aldehydes; Base Sequence; Deoxyguanosine; DNA Adducts; DNA Repair; Mutagenesis; Oligodeoxyribonucleotides | 2009 |
Use of In Vivo and In Vitro Data to Derive a Chronic Reference Value for Crotonaldehyde Based on Relative Potency to Acrolein.
Topics: Acrolein; Aldehydes; Animals; Environmental Pollutants; Humans; Mice; Rats; Reference Values; Risk Assessment | 2015 |
Chemistry and analysis of HNE and other prominent carbonyl-containing lipid oxidation compounds.
Topics: Acrolein; Aldehydes; Animals; Humans; Isoprostanes; Lactoglobulins; Lipid Peroxidation; Oxidative Stress; Protein Processing, Post-Translational | 2017 |
3 trial(s) available for acrolein and 2-butenal
| Article | Year |
|---|---|
Influence of smoking charcoal filter tipped cigarettes on various biomarkers of exposure.
Topics: Acrolein; Aldehydes; Biomarkers; Butadienes; Cellulose; Charcoal; Cross-Over Studies; Filtration; Humans; Nicotiana; Smoke; Smoking; Sulfhydryl Compounds | 2006 |
Modulation of the metabolism of airborne pollutants by glucoraphanin-rich and sulforaphane-rich broccoli sprout beverages in Qidong, China.
Topics: Acetylcysteine; Acrolein; Adult; Air Pollutants; Aldehydes; Benzene; Beverages; Biomarkers; Brassica; China; DNA Adducts; Ethylene Oxide; Female; Glucosinolates; Humans; Imidoesters; Isothiocyanates; Male; Middle Aged; Oximes; Polycyclic Aromatic Hydrocarbons; Smoking; Sulfoxides; Thiocyanates | 2012 |
2-Phenethyl Isothiocyanate, Glutathione S-transferase M1 and T1 Polymorphisms, and Detoxification of Volatile Organic Carcinogens and Toxicants in Tobacco Smoke.
Topics: Acrolein; Adult; Aldehydes; Benzene; Carcinogens; Cross-Over Studies; Enzyme Inhibitors; Female; Glutathione Transferase; Humans; Inactivation, Metabolic; Isothiocyanates; Male; Middle Aged; Nicotiana; Polymorphism, Single Nucleotide; Smoke; Smoking; Volatile Organic Compounds | 2016 |
63 other study(ies) available for acrolein and 2-butenal
| Article | Year |
|---|---|
The lipid peroxidation product 4-hydroxynonenal is a potent inducer of the SOS response.
Topics: Acrolein; Aldehydes; Lipid Peroxidation; Malondialdehyde; Mutagens; Operon; Salmonella typhimurium; SOS Response, Genetics | 1992 |
Detection of acrolein and crotonaldehyde DNA adducts in cultured human cells and canine peripheral blood lymphocytes by 32P-postlabeling and nucleotide chromatography.
Topics: Acrolein; Aldehydes; Animals; Cells, Cultured; Chromatography, Thin Layer; Cyclophosphamide; Deoxyribonucleotides; DNA; Dogs; Dose-Response Relationship, Drug; Humans; Nucleotides; Phosphorus Radioisotopes | 1991 |
Formation of cyclic deoxyguanosine adducts in Chinese hamster ovary cells by acrolein and crotonaldehyde.
Topics: Acrolein; Aldehydes; Animals; Cells, Cultured; Cricetinae; Deoxyguanosine; DNA; Mutagenicity Tests | 1990 |
Determination of acrolein and crotonaldehyde in automobile exhaust gas by gas chromatography with electron-capture detection.
Topics: Acrolein; Aldehydes; Electrochemistry; Gas Chromatography-Mass Spectrometry; Vehicle Emissions | 1987 |
Inhibition of microsomal cytochrome c reductase activity by a series of alpha, beta-unsaturated aldehydes.
Topics: Acrolein; Aldehydes; Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Glutathione; In Vitro Techniques; Male; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Oxidoreductases; Rats; Rats, Inbred Strains | 1987 |
Effects of alpha, beta-unsaturated aldehydes on macrophage and neutrophil membrane function, fluidity and sulfhydryl status.
Topics: Acrolein; Aldehydes; Cell Membrane; Humans; In Vitro Techniques; Macrophages; Membrane Fluidity; Neutrophils; Sulfhydryl Compounds | 1988 |
Formation of cyclic 1,N2-propanodeoxyguanosine adducts in DNA upon reaction with acrolein or crotonaldehyde.
Topics: Acrolein; Aldehydes; Animals; Cattle; Chromatography, High Pressure Liquid; Cyclic GMP; DNA; Magnetic Resonance Spectroscopy; Solvents; Spectrophotometry, Ultraviolet; Thymus Gland | 1984 |
The acute effects of single and repeated injections of acrolein and other aldehydes.
Topics: Acrolein; Adrenal Glands; Aldehydes; Animals; Atrophy; Corticosterone; Dose-Response Relationship, Drug; Erythrocytes; Formaldehyde; Inactivation, Metabolic; L-Lactate Dehydrogenase; Liver; Mice; Necrosis; Spleen; Thymus Gland | 1984 |
Effects of cigarette smoke and its constituents on the adherence of polymorphonuclear leukocytes.
Topics: Acrolein; Adult; Aldehydes; Cell Adhesion; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Glutathione; Humans; Hydroxymercuribenzoates; Male; Neutrophils; Smoke | 1980 |
Plasma protein sulfhydryl oxidation: effect of low molecular weight thiols.
Topics: Acrolein; Aldehydes; Blood Proteins; Humans; Kinetics; Nitrogen Oxides; Oxidation-Reduction; Ozone; Smoking; Sulfhydryl Compounds; Sulfites; Thioctic Acid | 1995 |
Detection of exocyclic 1,N2-propanodeoxyguanosine adducts as common DNA lesions in rodents and humans.
Topics: Acrolein; Adult; Aged; Aged, 80 and over; Aldehydes; Animals; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA Damage; Female; Humans; Liver; Male; Mice; Middle Aged; Rats; Reference Standards; Stereoisomerism | 1994 |
A 32P-postlabeling method for simultaneous detection and quantification of exocyclic etheno and propano adducts in DNA.
Topics: Acrolein; Aldehydes; Deoxyguanosine; DNA; Isotope Labeling; Phosphorus Radioisotopes; Stereoisomerism | 1994 |
Detection of 1, N2-propanodeoxyguanosine adducts as potential endogenous DNA lesions in rodent and human tissues.
Topics: Acrolein; Adult; Aldehydes; Animals; Carcinogens; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA; DNA Adducts; DNA Damage; Female; Humans; Male; Mice; Mice, Inbred A; Middle Aged; Phosphorus Radioisotopes; Rats; Rats, Inbred F344 | 1996 |
Inhibition of glutathione S-transferase activity in human melanoma cells by alpha,beta-unsaturated carbonyl derivatives. Effects of acrolein, cinnamaldehyde, citral, crotonaldehyde, curcumin, ethacrynic acid, and trans-2-hexenal.
Topics: Acrolein; Acyclic Monoterpenes; Aldehydes; Chromatography, High Pressure Liquid; Curcumin; Enzyme Inhibitors; Ethacrynic Acid; Glutathione; Glutathione Transferase; Humans; Melanoma; Monoterpenes; Skin Neoplasms; Terpenes; Tumor Cells, Cultured | 1996 |
Inactivation of glutathione reductase by 4-hydroxynonenal and other endogenous aldehydes.
Topics: Acrolein; Aldehydes; Amino Acids; Deoxyglucose; Enzyme Activation; Glutathione Reductase; Ketoses; Pyruvaldehyde; Spectrometry, Fluorescence | 1997 |
Interactions of alpha, beta-unsaturated aldehydes and ketones with human glutathione S-transferase P1-1.
Topics: Acrolein; Aldehydes; Curcumin; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Ethacrynic Acid; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Isoenzymes; Ketones; Mutagenesis, Site-Directed | 1997 |
Structures of acrolein-guanine adducts: a semi-empirical self-consistent field and nuclear magnetic resonance spectral study.
Topics: Acrolein; Aldehydes; DNA Adducts; Guanine; Magnetic Resonance Spectroscopy; Mutagens | 1998 |
32P-postlabelling with high-performance liquid chromatography for analysis of abundant DNA adducts in human tissues.
Topics: Acrolein; Adult; Age Factors; Aged; Aldehydes; Animals; Breast; Breast Neoplasms; Chromatography, High Pressure Liquid; Colon; DNA Adducts; Female; Humans; Lung; Male; Middle Aged; Phosphorus Radioisotopes; Rats; Tissue Distribution | 1999 |
Catalytic efficiencies of allelic variants of human glutathione S-transferase Pi in the glutathione conjugation of alpha, beta-unsaturated aldehydes.
Topics: Acrolein; Aldehydes; Alleles; Catalysis; Dose-Response Relationship, Drug; Glutathione; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Isoenzymes; Kinetics; Polymorphism, Genetic; Protein Isoforms | 2000 |
Formation of cyclic deoxyguanosine adducts from omega-3 and omega-6 polyunsaturated fatty acids under oxidative conditions.
Topics: Acrolein; Aldehydes; alpha-Linolenic Acid; Arachidonic Acid; Chromatography, High Pressure Liquid; Deoxyguanine Nucleotides; Deoxyguanosine; DNA Adducts; DNA Damage; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Fatty Acids, Unsaturated; Linoleic Acid; Oxidation-Reduction; Stearic Acids | 2002 |
Tumorigenicity of chloral hydrate, trichloroacetic acid, trichloroethanol, malondialdehyde, 4-hydroxy-2-nonenal, crotonaldehyde, and acrolein in the B6C3F(1) neonatal mouse.
Topics: Acrolein; Aldehydes; Animals; Animals, Newborn; Carcinogenicity Tests; Carcinogens; Chloral Hydrate; Chromatography, High Pressure Liquid; Crosses, Genetic; DNA; DNA Adducts; Electrochemistry; Ethylene Chlorohydrin; Female; Lipid Peroxidation; Liver; Liver Neoplasms, Experimental; Male; Malondialdehyde; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Microsomes, Liver; Phosphorus Radioisotopes; Trichloroacetic Acid | 2002 |
1,N2-deoxyguanosine adducts of acrolein, crotonaldehyde, and trans-4-hydroxynonenal cross-link to peptides via Schiff base linkage.
Topics: Acrolein; Aldehydes; Amino Acid Sequence; Cross-Linking Reagents; Deoxyguanosine; DNA Adducts; Kinetics; Models, Molecular; Molecular Structure; Oligopeptides; Schiff Bases | 2003 |
DNA interchain cross-links formed by acrolein and crotonaldehyde.
Topics: Acrolein; Aldehydes; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; CpG Islands; Cross-Linking Reagents; DNA; DNA Adducts; Electrophoresis, Capillary; Nuclear Magnetic Resonance, Biomolecular; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Substrate Specificity | 2003 |
DNA damage caused by lipid peroxidation products.
Topics: Acrolein; Aldehydes; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; DNA Adducts; DNA Damage; Lipid Peroxidation | 2003 |
The effect of tetraethylthiuramdisulphide (disulfiram) upon the toxicity of lower aliphatic aldehydes (formaldehyde, acetaldehyde, propionaldehyde, butyraldehyde, acrolein and crotonaldehyde).
Topics: Acetaldehyde; Acrolein; Aldehydes; Disulfiram; Formaldehyde; Humans | 1951 |
Reactivity of hydrazinophthalazine drugs with the lipid peroxidation products acrolein and crotonaldehyde.
Topics: Acrolein; Aldehydes; Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Culture Media; Hepatocytes; Hydralazine; Kinetics; Lipid Peroxidation; Mice; Molecular Structure | 2004 |
Optimizing a dansylhydrazine (DNSH) based method for measuring airborne acrolein and other unsaturated carbonyls.
Topics: Acrolein; Air Pollutants; Aldehydes; Chromatography, High Pressure Liquid; Dansyl Compounds; Environmental Monitoring; Hydrazines | 2005 |
Crotonaldehyde accumulates in glial cells of Alzheimer's disease brain.
Topics: Acrolein; Aged; Aged, 80 and over; Aldehydes; Alzheimer Disease; Astrocytes; Brain; Female; Humans; Lipid Peroxidation; Male; Middle Aged; Neuroglia; Oxidative Stress | 2006 |
A sensitive method for the quantification of acrolein and other volatile carbonyls in ambient air.
Topics: Acrolein; Air Pollutants; Aldehydes; Benzaldehydes; Butanones; Chromatography, Gas; Environmental Monitoring; Glyoxal; Hydrazines; Ketones; Mass Spectrometry; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Sulfites; Volatilization; Water | 2006 |
A fluorescence-based screening assay for DNA damage induced by genotoxic industrial chemicals.
Topics: Acetone; Acrolein; Aldehydes; Allylamine; DNA; DNA Damage; Fluorescence; Formaldehyde; Hydrocarbons, Brominated; Mutagens; Transition Temperature | 2007 |
Acrolein inhibits cytokine gene expression by alkylating cysteine and arginine residues in the NF-kappaB1 DNA binding domain.
Topics: Acrolein; Aldehydes; Arginine; Cells, Cultured; Cysteine; Cytokines; DNA; Gene Expression Regulation; Humans; Lung; NF-kappa B p50 Subunit; NFATC Transcription Factors; Nicotiana; Protein Binding; Respiratory Tract Infections; Smoke; T-Lymphocytes; Transcription Factor AP-1 | 2007 |
Aldo-keto reductase family 1 B10 gene silencing results in growth inhibition of colorectal cancer cells: Implication for cancer intervention.
Topics: Acrolein; Aldehyde Reductase; Aldehydes; Aldo-Keto Reductases; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; DNA; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Kinetics; RNA, Small Interfering; Sensitivity and Specificity | 2007 |
Cells deficient in the FANC/BRCA pathway are hypersensitive to plasma levels of formaldehyde.
Topics: Acetaldehyde; Acrolein; Aldehydes; Animals; BRCA1 Protein; Cell Cycle; Cell Survival; Chickens; Cross-Linking Reagents; Disinfectants; DNA Damage; DNA Repair; Fanconi Anemia; Fanconi Anemia Complementation Group D2 Protein; Formaldehyde; Glutathione; Glyoxal; Pyruvaldehyde; Recombination, Genetic; Signal Transduction | 2007 |
Night-time atmospheric fate of acrolein and crotonaldehyde.
Topics: Acrolein; Aldehydes; Atmosphere; Kinetics | 2008 |
Cigarette smoke-induced neurogenic inflammation is mediated by alpha,beta-unsaturated aldehydes and the TRPA1 receptor in rodents.
Topics: Acrolein; Aldehydes; Animals; Ankyrins; Calcitonin Gene-Related Peptide; Calcium Channels; Calcium Signaling; Cell Line; Ganglia, Spinal; Guinea Pigs; Humans; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurogenic Inflammation; Neurons, Afferent; Nicotiana; Rats; Smoke; Substance P; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPC Cation Channels | 2008 |
How irritating: the role of TRPA1 in sensing cigarette smoke and aerogenic oxidants in the airways.
Topics: Acrolein; Air Pollutants; Aldehydes; Animals; Calcium Channels; Guinea Pigs; Mice; Models, Biological; Neurogenic Inflammation; Neurons, Afferent; Nicotiana; Oxidants; Respiratory Hypersensitivity; Respiratory System; Respiratory Tract Diseases; Smoke; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels | 2008 |
Evaluation of the toxicity of stress-related aldehydes to photosynthesis in chloroplasts.
Topics: Acrolein; Aldehydes; Ascorbic Acid; Chloroplasts; Cysteine; Electron Transport; Enzyme Activation; Glutathione; Light; Oxidation-Reduction; Photosynthesis; Spinacia oleracea; Stress, Physiological | 2009 |
Water-Soluble alpha,beta-unsaturated aldehydes of cigarette smoke induce carbonylation of human serum albumin.
Topics: Acrolein; Aldehydes; Arginine; Blotting, Western; Chromatography, Liquid; Electrophoresis, Polyacrylamide Gel; Humans; Lysine; Nicotiana; Protein Carbonylation; Serum Albumin; Smoke; Tandem Mass Spectrometry | 2010 |
Simultaneous quantification of 1,N2-propano-2'-deoxyguanosine adducts derived from acrolein and crotonaldehyde in human placenta and leukocytes by isotope dilution nanoflow LC nanospray ionization tandem mass spectrometry.
Topics: Acrolein; Aldehydes; Biomarkers; Chromatography, Liquid; Clinical Chemistry Tests; Deoxyguanosine; DNA; DNA Damage; Feasibility Studies; Female; Humans; Isotopes; Leukocytes; Nanotechnology; Placenta; Pregnancy; Reproducibility of Results; Stereoisomerism; Tandem Mass Spectrometry; Time Factors | 2009 |
Effect of protein modification by malondialdehyde on the interaction between the oxygen-evolving complex 33 kDa protein and photosystem II core proteins.
Topics: Acrolein; Aldehydes; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Hot Temperature; Intracellular Membranes; Lipid Peroxidation; Malondialdehyde; Photosystem II Protein Complex; Plant Leaves; Protein Binding; Protein Processing, Post-Translational; Spinacia oleracea; Stress, Physiological; Thylakoids | 2010 |
Carbonyl compound emissions from a heavy-duty diesel engine fueled with diesel fuel and ethanol-diesel blend.
Topics: Acetaldehyde; Acetone; Acrolein; Air Pollutants; Aldehydes; Ethanol; Formaldehyde; Gasoline; Vehicle Emissions | 2010 |
Cigarette smoke and α,β-unsaturated aldehydes elicit VEGF release through the p38 MAPK pathway in human airway smooth muscle cells and lung fibroblasts.
Topics: Acetylcysteine; Acrolein; Aldehydes; Bronchi; Calcium Channels; Cells, Cultured; Complex Mixtures; Fibroblasts; Humans; Lung; Myocytes, Smooth Muscle; Nerve Tissue Proteins; Nicotiana; Nicotinic Antagonists; p38 Mitogen-Activated Protein Kinases; Phosphorylation; RNA, Messenger; Smoke; Transient Receptor Potential Channels; TRPA1 Cation Channel; Vascular Endothelial Growth Factor A | 2011 |
Genotoxic analysis of four lipid-peroxidation products in the mouse lymphoma assay.
Topics: Acrolein; Aldehydes; Animals; Dose-Response Relationship, Drug; Lipid Peroxidation; Lymphoma; Mice; Mutagenicity Tests; Mutagens | 2011 |
Human aldo-keto reductase AKR7A2 protects against the cytotoxicity and mutagenicity of reactive aldehydes and lowers intracellular reactive oxygen species in hamster V79-4 cells.
Topics: Acrolein; Aldehyde Reductase; Aldehydes; Animals; Caspase 3; Cell Line; Cricetinae; DNA Damage; Glutathione; Humans; Mutagenicity Tests; Oxidative Stress; Pyruvaldehyde; Reactive Oxygen Species | 2012 |
Consideration of reactivity to acute fish toxicity of α,β-unsaturated carbonyl ketones and aldehydes.
Topics: Acrolein; Aldehydes; Animals; Fishes; Glutathione; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Ketones; Quantitative Structure-Activity Relationship; Sulfhydryl Compounds; Thermodynamics | 2012 |
Mutagenic/recombinogenic effects of four lipid peroxidation products in Drosophila.
Topics: Acrolein; Aldehydes; Animals; Chromosome Breakage; Dose-Response Relationship, Drug; Drosophila melanogaster; Lipid Peroxidation; Mitosis; Mutagenicity Tests; Mutagens; Mutation; Recombination, Genetic; Wings, Animal | 2013 |
Effects of aliphatic aldehydes on the growth and patulin production of Penicillium expansum in apple juice.
Topics: Acrolein; Acyltransferases; Aldehydes; Beverages; Fermentation; Fruit; Fungal Proteins; Gene Expression; Ligases; Malus; Multienzyme Complexes; Mycelium; Oxidoreductases; Patulin; Penicillium; Spores, Fungal; Transcription, Genetic | 2013 |
High throughput liquid chromatography-tandem mass spectrometry assay for mercapturic acids of acrolein and crotonaldehyde in cigarette smokers' urine.
Topics: Acetylcysteine; Acrolein; Aldehydes; Chromatography, Liquid; High-Throughput Screening Assays; Humans; Limit of Detection; Reproducibility of Results; Smoking; Solid Phase Extraction; Tandem Mass Spectrometry | 2013 |
Development of three stable isotope dilution assays for the quantitation of (E)-2-butenal (crotonaldehyde) in heat-processed edible fats and oils as well as in food.
Topics: Acrolein; Aldehydes; Carbon Isotopes; Coconut Oil; Dietary Fats; Dietary Fats, Unsaturated; Food Analysis; Food Handling; Gas Chromatography-Mass Spectrometry; Hot Temperature; Indicator Dilution Techniques; Isotopes; Linseed Oil; Plant Oils; Time Factors | 2014 |
A toxicological investigation of lower aliphatic aldehydes. I. Toxicity of formaldehyde, acetaldehyde; propionaldehyde and butyraldehyde; as well as of acrolein and crotonaldehyde.
Topics: Acetaldehyde; Acrolein; Aldehydes; Formaldehyde; Humans | 1950 |
Elevated levels of mercapturic acids of acrolein and crotonaldehyde in the urine of Chinese women in Singapore who regularly cook at home.
Topics: Acetylcysteine; Acrolein; Aged; Aldehydes; Asian People; Benzene; Biomarkers; Carcinogens; Cooking; Female; Humans; Lung Neoplasms; Middle Aged; Singapore; Smoking | 2015 |
Mercapturic Acids Derived from the Toxicants Acrolein and Crotonaldehyde in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer.
Topics: Acetylcysteine; Acrolein; Aged; Aldehydes; Ethnicity; Female; Hawaii; Humans; Lung Neoplasms; Male; Middle Aged; Risk Factors; Smoking | 2015 |
Reactive Carbonyl Species Derived from Omega-3 and Omega-6 Fatty Acids.
Topics: Acrolein; Aldehydes; alpha-Linolenic Acid; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Linoleic Acid; Lipid Peroxidation; Oxidation-Reduction | 2015 |
Lipidomic analysis for carbonyl species derived from fish oil using liquid chromatography-tandem mass spectrometry.
Topics: Acrolein; Aldehydes; Chromatography, Liquid; Fish Oils; Glyoxal; Lipid Peroxidation; Lipids; Oxidation-Reduction; Pyruvaldehyde; Tandem Mass Spectrometry | 2017 |
Measures of odor and lateralization thresholds of acrolein, crotonaldehyde, and hexanal using a novel vapor delivery technique.
Topics: Acrolein; Adult; Aldehydes; Female; Humans; Male; Odorants; Sensory Thresholds; Young Adult | 2017 |
Carbonyl emissions from a novel heated tobacco product (IQOS): comparison with an e-cigarette and a tobacco cigarette.
Topics: Acetaldehyde; Acrolein; Aerosols; Aldehydes; Electronic Nicotine Delivery Systems; Formaldehyde; Humans; Nicotiana; Smoke; Tobacco Products | 2018 |
Detoxification Mechanism of α,β-Unsaturated Carbonyl Compounds in Cigarette Smoke Observed in Sheep Erythrocytes.
Topics: Acrolein; Aldehydes; Animals; Butanones; Cigarette Smoking; Erythrocytes; Sheep; Smoke; Tobacco Products | 2018 |
Resolution and Quantitation of Mercapturic Acids Derived from Crotonaldehyde, Methacrolein, and Methyl Vinyl Ketone in the Urine of Smokers and Nonsmokers.
Topics: Acetylcysteine; Acrolein; Aldehydes; Butanones; Humans; Molecular Structure; Non-Smokers; Smokers | 2020 |
Carcinogenicity of acrolein, crotonaldehyde, and arecoline.
Topics: Acrolein; Aldehydes; Animals; Arecoline; Carcinogenicity Tests; Carcinogens, Environmental; Consensus Development Conferences as Topic; Environmental Exposure; Humans; Internet; Neoplasms; Risk Assessment; Telecommunications | 2021 |
Exposure to volatile organic compounds - acrolein, 1,3-butadiene, and crotonaldehyde - is associated with vascular dysfunction.
Topics: Acrolein; Air Pollutants; Air Pollution; Aldehydes; Bayes Theorem; Butadienes; Environmental Exposure; Environmental Monitoring; Humans; Particulate Matter; Volatile Organic Compounds | 2021 |
Comparison of urinary mercapturic acid excretions in users of various tobacco/nicotine products.
Topics: Acetylcysteine; Acrolein; Acrylamides; Biomarkers; Carcinogens; Electronic Nicotine Delivery Systems; Humans; Nicotiana; Nicotine; Smoking Cessation; Tobacco Use Cessation Devices | 2023 |
Exposure to Volatile Organic Compounds Is Associated with Hypertension in Black Adults: The Jackson Heart Study.
Topics: Acrolein; Adult; Bayes Theorem; Humans; Hypertension; Longitudinal Studies; Male; Styrenes; Volatile Organic Compounds | 2023 |
Single-chemical and mixture effects of multiple volatile organic compounds exposure on liver injury and risk of non-alcoholic fatty liver disease in a representative general adult population.
Topics: Acrolein; Acrylamides; Acrylonitrile; Adult; Bayes Theorem; Biomarkers; Cross-Sectional Studies; Dimethylformamide; Humans; Non-alcoholic Fatty Liver Disease; Nutrition Surveys; Styrenes; Toluene; United States; Volatile Organic Compounds; Xylenes | 2023 |