acridines and thiourea
acridines has been researched along with thiourea in 25 studies
Research
Studies (25)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (20.00) | 18.7374 |
| 1990's | 1 (4.00) | 18.2507 |
| 2000's | 11 (44.00) | 29.6817 |
| 2010's | 8 (32.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Chance, B; Cohen, PJ; Kumar, C; Lee, HC; Okuda, M | 1 |
| Gibel, W; Schramm, T; Schwabe, K | 1 |
| Collins, J; Cramp, WA; Fraval, HN | 1 |
| Stewart, JT | 1 |
| Cramp, WA; Watkins, DK | 1 |
| Burckhalter, JH; de Leenheer, A; Sinsheimer, JE | 1 |
| Baruah, H; Bierbach, U; Day, CS; Kramarczyk, J; Kucera, GL; Martins, ET; Saluta, G | 1 |
| Barry, CG; Bierbach, U; Day, CS; Kucera, GL; Saluta, G; Turney, EC | 1 |
| Anderson, J; Augustus, TM; Bierbach, U; Hess, SM | 1 |
| Johar, M; Lown, JW; Reddy, BS; Singhal, N; Sondhi, SM | 1 |
| Baruah, H; Bierbach, U | 1 |
| Ramamurthy, P; Thiagarajan, V | 1 |
| Bierbach, U; Choudhury, JR; Day, CS; Guddneppanavar, R; Kheradi, AR; Kucera, GL; Saluta, G; Steen, BD | 1 |
| Bierbach, U; Kucera, GL; Ma, Z; Saluta, G | 1 |
| Bierbach, U; Ma, Z; Rao, L | 1 |
| Imrich, J; Janovec, L; Kozurková, M; Kristian, P; Paulíková, H; Sabolová, D; Suchánová, M; Vantová, Z | 1 |
| Bierbach, U; Day, CS; Eiter, LC; Hall, NW; Kucera, GL; Saluta, G | 1 |
| Bierbach, U; Brabec, V; Kasparkova, J; Kostrhunova, H; Malina, J; Muchova, T; Pickard, AJ; Rohlfing, ML; Stepankova, J; Vojtiskova, M | 1 |
| Bierbach, U; Binz, KL; Dutta, S; Guthold, M; Roll, EH; Rosile, D; Snyder, MJ; Suryadi, J | 1 |
| Böhm, S; Danihel, I; Hamulakova, S; Holas, O; Imrich, J; Janovec, L; Kozurkova, M; Kristian, P; Kuca, K; Pohanka, M | 1 |
| Bečka, M; Brabec, V; Kašpárková, J; Kožurková, M; Salem, O; Vilková, M | 1 |
| Kožurková, M; Kristian, P; Sabolová, D | 1 |
| Bautista, D; Brabec, V; de Haro, C; Donaire, A; Kostrhunova, H; Pérez, SA; Ruiz, J; Vicente, C; Zajac, J; Zamora, A | 1 |
| Kozurkova, M; Othman, S | 1 |
| Babkova, K; Brabec, V; Fedorocko, P; Hamulakova, S; Janockova, J; Jendzelovsky, R; Kasparkova, J; Konkolova, E; Korabecny, J; Koval, J; Kozurkova, M; Kuca, K; Kucerova, D; Plsikova, J; Rosocha, J; Soukup, O; Vargova, J | 1 |
Reviews
4 review(s) available for acridines and thiourea
| Article | Year |
|---|---|
[Recommendations for testing and evaluation of drugs as to carcinogenicity].
Topics: Acridines; Alcohols; Alkylating Agents; Animals; Antithyroid Agents; Azo Compounds; Carbazoles; Carcinogens; Coal Tar; Dextrans; Estrogens; Immunosuppressive Agents; Iron; Lactones; Methylthiouracil; Naphthoquinones; Paraffin; Phenylbutazone; Reserpine; Sulfhydryl Compounds; Sulfonamides; Sulfonic Acids; Tannins; Thiourea; Toxicology; Triazoles; Urethane; World Health Organization | 1971 |
Heterocyclic compounds as inflammation inhibitors.
Topics: Acridines; Alkanes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzimidazoles; Carboxylic Acids; Gastrointestinal Diseases; Heterocyclic Compounds; Humans; Imidazoles; Pyrimidines; Thiazoles; Thiourea | 2002 |
A review on acridinylthioureas and its derivatives: biological and cytotoxic activity.
Topics: Acridines; Antineoplastic Agents; Cell Line, Tumor; DNA Damage; Humans; Isothiocyanates; Proflavine; Structure-Activity Relationship; Thiourea | 2017 |
Sulfur Containing Acridine Derivatives in Preclinical Studies with Cancer Cell Lines.
Topics: Acridines; Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Thiazolidines; Thiosemicarbazones; Thiourea | 2018 |
Other Studies
21 other study(ies) available for acridines and thiourea
| Article | Year |
|---|---|
Phorbol myristate acetate-induced lung injury: involvement of reactive oxygen species.
Topics: Acridines; Animals; Catalase; Indomethacin; Luminescent Measurements; Lung; Lung Diseases; Male; Pressure; Pulmonary Artery; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Thiourea | 1992 |
The effect of radiation sensitizing and protective agents on the post-irradiation synthesis of DNA by membrane complexes of Escherichia coli B-r.
Topics: Acridines; Anaerobiosis; Cell Membrane; Chlorides; Copper; DNA, Bacterial; Dose-Response Relationship, Radiation; Escherichia coli; Glycerol; Mercaptoethanol; Oxygen; Radiation Effects; Radiation-Protective Agents; Radiation-Sensitizing Agents; Thiourea | 1973 |
Synthesis and biological activity of 9-substituted acridines.
Topics: Acridines; Animals; Bacteria; Carbamates; Dogs; Esters; Gastric Juice; Gastrins; Larva; Nematode Infections; Thiourea | 1973 |
The modification of post-irradiation DNA degradation in Escherichia coli B/r.
Topics: Acridines; Carbon Isotopes; Dimethyl Sulfoxide; DNA, Bacterial; Electrons; Escherichia coli; Ethylmaleimide; Glycerol; Indenes; Ketones; Radiation Effects; Radiation-Protective Agents; Radiation-Sensitizing Agents; Thiourea; Thymine | 1970 |
Photochemical cyclization of N-butyl-N'-(9-acridinyl)thiourea.
Topics: Acridines; Chromatography, Gas; Chromatography, Thin Layer; Cyclization; Fluorescence; Infrared Rays; Magnetic Resonance Spectroscopy; Mass Spectrometry; Photochemistry; Spectrum Analysis; Thiourea; Ultraviolet Rays | 1972 |
Design, synthesis, and biological activity of a novel non-cisplatin-type platinum-acridine pharmacophore.
Topics: Acridines; Antineoplastic Agents; Cisplatin; Drug Design; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Magnetic Resonance Spectroscopy; Organoplatinum Compounds; Structure-Activity Relationship; Thiourea; Tumor Cells, Cultured | 2001 |
Thermally inert metal ammines as light-inducible DNA-targeted agents. Synthesis, photochemistry, and photobiology of a prototypical rhodium(III)-intercalator conjugate.
Topics: Acridines; Animals; Antineoplastic Agents; Cattle; Chemical Phenomena; Chemistry; DNA; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Electrophoresis, Agar Gel; Escherichia coli; Humans; Intercalating Agents; Magnetic Resonance Spectroscopy; Molecular Structure; Organometallic Compounds; Photochemistry; Rhodium; Structure-Activity Relationship; Thiourea; Tumor Cells, Cultured | 2002 |
Bis(acridinylthiourea)platinum(II) complexes: synthesis, DNA affinity, and biological activity in glioblastoma cells.
Topics: Acridines; Animals; Antineoplastic Agents; Cattle; Cell Survival; DNA; Glioblastoma; Humans; Intercalating Agents; Organoplatinum Compounds; Spectrophotometry, Ultraviolet; Thiourea; Tumor Cells, Cultured | 2003 |
Unusual intercalation of acridin-9-ylthiourea into the 5'-GA/TC DNA base step from the minor groove: implications for the covalent DNA adduct profile of a novel platinum-intercalator conjugate.
Topics: Acridines; Base Pairing; Base Sequence; Binding, Competitive; DNA; DNA Adducts; Intercalating Agents; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Platinum; Thermodynamics; Thiourea | 2003 |
Fluorescent sensing of anions with acridinedione based neutral PET chemosensor.
Topics: Acetonitriles; Acridines; Anions; Binding Sites; Biosensing Techniques; Electron Transport; Fluorescence; Fluorescent Dyes; Hydrogen Bonding; Molecular Structure; Oxidation-Reduction; Photochemistry; Solvents; Spectrophotometry, Ultraviolet; Thiourea; Time Factors; Titrimetry | 2007 |
Effect of the diamine nonleaving group in platinum-acridinylthiourea conjugates on DNA damage and cytotoxicity.
Topics: Acridines; Antineoplastic Agents; Base Sequence; Cell Line, Tumor; Cisplatin; DNA Damage; Drug Screening Assays, Antitumor; Humans; Molecular Sequence Data; Organoplatinum Compounds; Stereoisomerism; Structure-Activity Relationship; Thiourea | 2007 |
Effect of linkage geometry on biological activity in thiourea- and guanidine-substituted acridines and platinum-acridines.
Topics: Acridines; Antineoplastic Agents; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Design; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Guanidine; HL-60 Cells; Humans; Inhibitory Concentration 50; Models, Chemical; Platinum; Structure-Activity Relationship; Thiourea; Urea | 2008 |
Replacement of a thiourea-S with an amidine-NH donor group in a platinum-acridine antitumor compound reduces the metal's reactivity with cysteine sulfur.
Topics: Acridines; Amidines; Antineoplastic Agents; Chemical Phenomena; Cysteine; DNA; Platinum Compounds; Structure-Activity Relationship; Thiourea | 2009 |
Cytotoxic activity of acridin-3,6-diyl dithiourea hydrochlorides in human leukemia line HL-60 and resistant subline HL-60/ADR.
Topics: Acridines; Antineoplastic Agents; Cell Death; Cell Proliferation; DNA; Drug Resistance, Neoplasm; HL-60 Cells; Humans; Leukemia; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Thiourea; Titrimetry; Transition Temperature | 2009 |
Gold(I) analogues of a platinum-acridine antitumor agent are only moderately cytotoxic but show potent activity against Mycobacterium tuberculosis.
Topics: Acridines; Animals; Antineoplastic Agents; Antitubercular Agents; Biological Availability; Cell Line, Tumor; Cell Proliferation; Chelating Agents; Chlorocebus aethiops; Coordination Complexes; DNA Adducts; DNA, Bacterial; Drug Screening Assays, Antitumor; Gold; Humans; Ligands; Mice; Mycobacterium tuberculosis; Organogold Compounds; Platinum; Structure-Activity Relationship; Thiourea; Urea; Vero Cells | 2009 |
Replacement of a thiourea with an amidine group in a monofunctional platinum-acridine antitumor agent. Effect on DNA interactions, DNA adduct recognition and repair.
Topics: Acridines; Amidines; Antineoplastic Agents; Cisplatin; DNA; DNA Adducts; DNA Repair; DNA, B-Form; Drug Design; HeLa Cells; HMGB1 Protein; Humans; Intercalating Agents; Kinetics; Nucleic Acid Conformation; Organoplatinum Compounds; Protein Isoforms; Structure-Activity Relationship; Thiourea; Transcription, Genetic | 2011 |
PT-ACRAMTU, a platinum-acridine anticancer agent, lengthens and aggregates, but does not stiffen or soften DNA.
Topics: Acridines; Antineoplastic Agents; DNA; DNA Adducts; DNA Breaks, Double-Stranded; Microscopy, Atomic Force; Organoplatinum Compounds; Particle Size; Platinum; Thiourea; Urea | 2013 |
Novel tacrine/acridine anticholinesterase inhibitors with piperazine and thiourea linkers.
Topics: Acetylcholinesterase; Acridines; Butyrylcholinesterase; Cholinesterase Inhibitors; Enzyme Activation; Humans; Models, Molecular; Molecular Conformation; Piperazine; Piperazines; Protein Binding; Tacrine; Thiourea | 2014 |
3-[(E)-(acridin-9'-ylmethylidene)amino]-1-substituted thioureas and their biological activity.
Topics: Acridines; Circular Dichroism; DNA; DNA Topoisomerases, Type I; Magnetic Resonance Spectroscopy; Models, Molecular; Spectrophotometry, Ultraviolet; Thiosemicarbazones; Thiourea; Topoisomerase I Inhibitors | 2017 |
New Acridine Thiourea Gold(I) Anticancer Agents: Targeting the Nucleus and Inhibiting Vasculogenic Mimicry.
Topics: Acridines; Angiogenesis Inhibitors; Antineoplastic Agents; Cell Line, Tumor; Cell Nucleus; Gold; Humans; Intercalating Agents; Molecular Mimicry; Neoplasm Invasiveness; Neovascularization, Pathologic; Thiourea | 2017 |
In vitro investigating of anticancer activity of new 7-MEOTA-tacrine heterodimers.
Topics: A549 Cells; Acridines; Antineoplastic Agents; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Fibroblasts; HL-60 Cells; Humans; Structure-Activity Relationship; Tacrine; Thiourea | 2019 |