acridines and plx4032
acridines has been researched along with plx4032 in 3 studies
Research
Studies (3)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Beijnen, JH; Durmus, S; Schinkel, AH; Sparidans, RW; Wagenaar, E | 1 |
| Gately, S; Goodall, ML; Kauffman, AL; Kortus, MG; MacKeigan, JP; Martin, KR; Trent, JM; Wang, T | 1 |
| Henderson, CJ; MacLeod, AK; McLaughlin, LA; Wolf, CR | 1 |
Other Studies
3 other study(ies) available for acridines and plx4032
| Article | Year |
|---|---|
Oral availability and brain penetration of the B-RAFV600E inhibitor vemurafenib can be enhanced by the P-GLYCOprotein (ABCB1) and breast cancer resistance protein (ABCG2) inhibitor elacridar.
Topics: Acridines; Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Availability; Biological Transport; Blood-Brain Barrier; Drug Combinations; Female; Humans; Indoles; Kidney; Madin Darby Canine Kidney Cells; Mice; Mice, Knockout; Multidrug Resistance-Associated Protein 2; Sulfonamides; Tetrahydroisoquinolines; Tissue Distribution; Vemurafenib | 2012 |
Development of potent autophagy inhibitors that sensitize oncogenic BRAF V600E mutant melanoma tumor cells to vemurafenib.
Topics: Acridines; Animals; Antimalarials; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Cell Line, Tumor; Chloroquine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Indoles; Lysosomes; Melanoma; Mice; Mutation; Proto-Oncogene Proteins B-raf; Structure-Activity Relationship; Sulfonamides; Translational Research, Biomedical; Tumor Stem Cell Assay; Vemurafenib | 2014 |
Activation status of the pregnane X receptor influences vemurafenib availability in humanized mouse models.
Topics: Acridines; Animals; Biological Availability; Biological Transport; Cell Line, Tumor; Constitutive Androstane Receptor; Cytochrome P-450 CYP3A; Female; Indoles; Male; Melanoma; Mice; Mice, Knockout; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Sulfonamides; Tetrahydroisoquinolines; Vemurafenib | 2015 |