Page last updated: 2024-08-21

acridines and morphine

acridines has been researched along with morphine in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199014 (73.68)18.7374
1990's2 (10.53)18.2507
2000's2 (10.53)29.6817
2010's1 (5.26)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fennessy, MR; Gaff, GA; Woo, JT1
Fearn, HJ; Fennessy, MR1
Fennessy, MR2
Fennessy, MR; Gaff, GA; Heimans, RL1
Lampard, DG; Redman, SJ1
Brouwer, KL; Brouwer, KR; Letrent, SP; Pollack, GM2
ACHOR, LB; GEILING, EM1
HUIDOBRO, F1
HUIDOBRO, F; MAGGIOLO, C1
DYRBERG, V; HOUGS, W; JOHANSEN, SH1
BRODIE, DC; LOWENHAUPT, E; WAY, EL1
BENTLEY, G; SHAW, FH1
Bouw, MR; Danhof, M; de Lange, EC; de Mik, D; Freijer, J; Groenendaal, D2
Croubels, S; Gadeyne, C; Gasthuys, F; Polis, I; Schauvliege, S; Van der Heyden, S1
Ortel, S1
Svensson, R1

Trials

1 trial(s) available for acridines and morphine

ArticleYear
The influence of modulation of P-glycoprotein and /or cytochrome P450 3A on the pharmacokinetics and pharmacodynamics of orally administered morphine in dogs.
    Journal of veterinary pharmacology and therapeutics, 2011, Volume: 34, Issue:5

    Topics: Absorption; Acridines; Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dogs; Enzyme Inhibitors; Female; Ketoconazole; Male; Morphine; Rifampin; Tetrahydroisoquinolines

2011

Other Studies

18 other study(ies) available for acridines and morphine

ArticleYear
A note on the effects of 2,4-diamino-5-phenylthiazole and 1, 2, 3, 4-tetrahydro-9-aminoacridine on morphine metabolism.
    The Journal of pharmacy and pharmacology, 1968, Volume: 20, Issue:10

    Topics: Acridines; Chromatography, Paper; Humans; Methods; Morphine; Spectrophotometry; Thiazoles

1968
Some observations on the toxicology of morphine-N-oxide.
    The Journal of pharmacy and pharmacology, 1969, Volume: 21, Issue:10

    Topics: Acridines; Animals; Body Weight; Female; Fetus; Growth; Morphinans; Morphine; Nalorphine; Oxides; Pregnancy; Rats; Spleen; Stomach; Thiazoles

1969
The behavioural, cardiovascular and respiratory actions of morphine-N-oxide in the dog.
    European journal of pharmacology, 1969, Volume: 8, Issue:3

    Topics: Acridines; Animals; Arousal; Atropine; Behavior, Animal; Blood Pressure; Cardiovascular System; Carotid Arteries; Cyclic N-Oxides; Dogs; Heart Rate; Histamine H1 Antagonists; Injections, Intravenous; Injections, Subcutaneous; Morphinans; Morphine; Nalorphine; Pyridines; Respiration; Thiazoles

1969
Some aspects of the metabolism of morphine-N-oxide.
    The Journal of pharmacy and pharmacology, 1971, Volume: 23, Issue:11

    Topics: Acridines; Analgesics; Animals; Codeine; Cyclic N-Oxides; In Vitro Techniques; Injections, Intraperitoneal; Liver; Male; Methylation; Morphinans; Morphine; Rats; Thiazoles

1971
The analgesic action of morphine-n-oxide.
    British journal of pharmacology, 1968, Volume: 34, Issue:2

    Topics: Acridines; Analgesia; Animals; Cyclic N-Oxides; Hot Temperature; Injections, Intraperitoneal; Injections, Subcutaneous; Mice; Morphine; Pain; Rats; Tail; Thiazoles

1968
Stochastic stimulqtion for the pharmacological study of monosynaptic spinal reflexes.
    European journal of pharmacology, 1969, Volume: 5, Issue:2

    Topics: Acridines; Animals; Bemegride; Cats; Chloralose; Chloroform; Electric Stimulation; Ethers; Halothane; Methods; Methohexital; Morphine; Motor Neurons; Neural Conduction; Pentobarbital; Phenylacetates; Thiopental; Trichloroethylene

1969
Effect of GF120918, a potent P-glycoprotein inhibitor, on morphine pharmacokinetics and pharmacodynamics in the rat.
    Pharmaceutical research, 1998, Volume: 15, Issue:4

    Topics: Acridines; Administration, Oral; Analgesia; Analgesics, Opioid; Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Dose-Response Relationship, Drug; Injections, Intravenous; Isoquinolines; Male; Morphine; Morphine Derivatives; Rats; Rats, Sprague-Dawley; Tetrahydroisoquinolines

1998
Effects of a potent and specific P-glycoprotein inhibitor on the blood-brain barrier distribution and antinociceptive effect of morphine in the rat.
    Drug metabolism and disposition: the biological fate of chemicals, 1999, Volume: 27, Issue:7

    Topics: Acridines; Analgesics, Opioid; Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cerebral Cortex; Isoquinolines; Male; Microdialysis; Morphine; Rats; Rats, Sprague-Dawley; Tetrahydroisoquinolines

1999
Morphine antagonists. I. The distribution and excretion of morphine-C14 in the presence of N-allyl normorphine and 5-aminoacridine.
    The Journal of pharmacology and experimental therapeutics, 1956, Volume: 117, Issue:1

    Topics: Acridines; Aminacrine; Aminoacridines; Biological Transport; Coloring Agents; Humans; Morphine; Morphine Derivatives; Nalorphine

1956
EFFECTS OF SOME INDOLES AND ACRIDINE DERIVATIVES ON THE ANALGESIC EFFECT OF MORPHINE.
    Acta physiologica latino americana, 1963, Volume: 13

    Topics: Acridines; Analgesia; Analgesics; Indoles; Mice; Morphine; Nalorphine; Narcotic Antagonists; Pain; Pain Management; Reaction Time; Research; Toxicology; Tremor; Tryptophan

1963
STUDIES ON MORPHINE. V. EFFECTS OF VARIOUS ANTI-MORPHINE COMPOUNDS AND OF NORMORPHINE ON MICE IMPLANTED WITH PELLETS OF MORPHINE.
    Archives internationales de pharmacodynamie et de therapie, 1964, May-01, Volume: 149

    Topics: Acridines; Mice; Morphine; Morphine Derivatives; Nalorphine; Pharmacology; Research; Toxicology

1964
HYDROAMINACRINE. 3. EFFECT OF MORPHINE-INDUCED RESPIRATORY DEPRESSION IN THE CAT.
    Acta pharmacologica et toxicologica, 1964, Volume: 21

    Topics: Acridines; Cats; Central Nervous System Stimulants; Morphine; Nalorphine; Pharmacology; Pulmonary Valve Insufficiency; Research; Respiratory Insufficiency

1964
Studies on 9-aminoacridine antagonism of morphine and related drugs.
    Archives internationales de pharmacodynamie et de therapie, 1952, Volume: 89, Issue:1

    Topics: Acridines; Aminacrine; Coloring Agents; Hostility; Morphine

1952
Some aspects of the pharmacology of morphine with special reference to its antagonism by 5-amino-acridine and other chemically related compounds.
    The Medical journal of Australia, 1949, Dec-17, Volume: 2, Issue:25

    Topics: Acridines; Humans; Morphine

1949
Influence of biophase distribution and P-glycoprotein interaction on pharmacokinetic-pharmacodynamic modelling of the effects of morphine on the EEG.
    British journal of pharmacology, 2007, Volume: 151, Issue:5

    Topics: Acridines; Algorithms; Analgesics, Opioid; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Electroencephalography; Extracellular Fluid; Microdialysis; Models, Statistical; Morphine; Rats; Tetrahydroisoquinolines; Tissue Distribution

2007
Population pharmacokinetic modelling of non-linear brain distribution of morphine: influence of active saturable influx and P-glycoprotein mediated efflux.
    British journal of pharmacology, 2007, Volume: 151, Issue:5

    Topics: Acridines; Algorithms; Analgesics, Opioid; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood Gas Analysis; Brain; Dose-Response Relationship, Drug; Electroencephalography; Hypnotics and Sedatives; Male; Microdialysis; Midazolam; Morphine; Nonlinear Dynamics; Population; Rats; Rats, Wistar; Respiration, Artificial; Tetrahydroisoquinolines

2007
Proceedings: Experience with nalidixic acid-trypaflavine agar.
    Acta microbiologica Academiae Scientiarum Hungaricae, 1972, Volume: 19, Issue:4

    Topics: Acridines; Adult; Agar; Bacteriological Techniques; Culture Media; Evaluation Studies as Topic; Feces; Female; Humans; Infant; Listeria monocytogenes; Meconium; Nalidixic Acid; Pregnancy

1972
Entamoeba histolytica: encystation and cultivation of several isolates.
    Experimental parasitology, 1971, Volume: 30, Issue:2

    Topics: Acridines; Animals; Blood Proteins; Cattle; Cold Temperature; Colon; Culture Media; Dogs; Entamoeba histolytica; Feces; Filtration; Horses; Humans; Infant, Newborn; Intestines; Meconium; Metamorphosis, Biological; Starch; Sterilization; Swine; Time Factors

1971
chemdatabank.com