acridines and ly335979
acridines has been researched along with ly335979 in 13 studies
Research
Studies (13)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 6 (46.15) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Baughman, TM; Bell, MG; Cao, J; Dantzig, AH; Ehlhardt, WJ; Elmquist, WF; Gruber, J; Kroin, JS; Law, KL; Norman, BH; Shepard, RL; Shih, C; Starling, JJ; Winter, MA | 1 |
| Covey, DF; Luker, GD; Nilsson, KR; Piwnica-Worms, D | 1 |
| Bardelmeijer, HA; Beijnen, JH; Ouwehand, M; Schellens, JH; van Tellingen, O | 1 |
| Barron, D; Bavchvarov, BI; Castanys, S; Cortés-Selva, F; Costi, MP; Di Pietro, A; Gamarro, F; Maitrejean, M; Muñoz-Martínez, F; Parodi-Talice, A; Pérez-Victoria, FJ; Pérez-Victoria, JM | 1 |
| Bihorel, S; Camenisch, G; Lemaire, M; Scherrmann, JM | 2 |
| Elmquist, WF; Giri, N; Pan, G; Shaik, N | 1 |
| Agarwal, S; Chen, C; Chen, Y; Elmquist, WF; Shaik, NM; Yang, Z | 1 |
| Li, J; Li, Z; Liu, F; Wang, X; Zhang, Z; Zhuang, X | 1 |
| Ambudkar, SV; Chufan, EE; Kapoor, K | 1 |
| Abel, B; Ambudkar, SV; Chufan, EE; Shukla, S | 1 |
| Bakos, É; Kucsma, N; Német, O; Özvegy-Laczka, C; Patik, I; Szakács, G; Várady, G | 1 |
| Ambudkar, SV; Lusvarghi, S | 1 |
Other Studies
13 other study(ies) available for acridines and ly335979
| Article | Year |
|---|---|
Pharmacological characterization of LY335979: a potent cyclopropyldibenzosuberane modulator of P-glycoprotein.
Topics: Acridines; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Dibenzocycloheptenes; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Isoquinolines; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Quinidine; Quinolines; Structure-Activity Relationship; Tetrahydroisoquinolines; Tumor Cells, Cultured; Verapamil | 1997 |
Multidrug resistance (MDR1) P-glycoprotein enhances esterification of plasma membrane cholesterol.
Topics: 3T3 Cells; Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Membrane; Cholesterol; Cyclosporins; Dehydroepiandrosterone; Dibenzocycloheptenes; Drug Resistance, Multiple; Esterification; Humans; Isoquinolines; Mice; Progesterone; Quinolines; Stereoisomerism; Tetrahydroisoquinolines; Tumor Cells, Cultured; Verapamil | 1999 |
Efficacy of novel P-glycoprotein inhibitors to increase the oral uptake of paclitaxel in mice.
Topics: Acridines; Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzazepines; Biological Availability; Biological Transport, Active; Cyclosporine; Cyclosporins; Dibenzocycloheptenes; Drug Interactions; Female; Gastric Mucosa; In Vitro Techniques; Intestinal Mucosa; Intestines; Mice; Models, Biological; Paclitaxel; Quinolines; Stomach; Tetrahydroisoquinolines; Time Factors | 2004 |
Combination of suboptimal doses of inhibitors targeting different domains of LtrMDR1 efficiently overcomes resistance of Leishmania spp. to Miltefosine by inhibiting drug efflux.
Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Membrane; Chlorocebus aethiops; Cytosol; Dibenzocycloheptenes; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance; Humans; Leishmania; Mice; NIH 3T3 Cells; Phosphorylcholine; Protein Structure, Tertiary; Quinolines; Tetrahydroisoquinolines; Vero Cells | 2006 |
Modulation of the brain distribution of imatinib and its metabolites in mice by valspodar, zosuquidar and elacridar.
Topics: Acridines; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Benzamides; Blood-Brain Barrier; Brain; Carbon Radioisotopes; Cyclosporins; Dibenzocycloheptenes; Imatinib Mesylate; Male; Mice; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Quinolines; Tetrahydroisoquinolines | 2007 |
Influence of breast cancer resistance protein (Abcg2) and p-glycoprotein (Abcb1a) on the transport of imatinib mesylate (Gleevec) across the mouse blood-brain barrier.
Topics: Acridines; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Benzamides; Biological Transport, Active; Blood-Brain Barrier; Brain; Cyclosporins; Dibenzocycloheptenes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Imatinib Mesylate; Immunosuppressive Agents; Male; Mice; Mice, Knockout; Piperazines; Pyrimidines; Quinolines; Tetrahydroisoquinolines | 2007 |
P-glycoprotein-mediated active efflux of the anti-HIV1 nucleoside abacavir limits cellular accumulation and brain distribution.
Topics: Acridines; Adenosine Triphosphatases; Animals; Anti-HIV Agents; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Biological Transport, Active; Brain; Cell Line; Cell Membrane; Dibenzocycloheptenes; Dideoxynucleosides; Humans; Mice; Mice, Inbred Strains; Mice, Knockout; Molecular Structure; Quinolines; Reverse Transcriptase Inhibitors; Tetrahydroisoquinolines; Vinblastine; Zidovudine | 2007 |
P-glycoprotein and breast cancer resistance protein influence brain distribution of dasatinib.
Topics: Acridines; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Blood-Brain Barrier; Brain; Cell Line; Cell Membrane Permeability; Dasatinib; Dibenzocycloheptenes; Dogs; Drug Resistance, Neoplasm; Indicators and Reagents; Mass Spectrometry; Mice; Mice, Knockout; Neurons; Protein Kinase Inhibitors; Pyrimidines; Quinolines; Tetrahydroisoquinolines; Thiazoles; Vinblastine | 2009 |
P-Glycoprotein (ABCB1) limits the brain distribution of YQA-14, a novel dopamine D3 receptor antagonist.
Topics: Acridines; Adenosine; Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzoxazoles; Blood-Brain Barrier; Brain; Caco-2 Cells; Dibenzocycloheptenes; Diketopiperazines; Dopamine Antagonists; Half-Life; Heterocyclic Compounds, 4 or More Rings; Humans; Mice; Permeability; Piperazines; Quinolines; ROC Curve; Temperature; Tetrahydroisoquinolines | 2015 |
Drug-protein hydrogen bonds govern the inhibition of the ATP hydrolysis of the multidrug transporter P-glycoprotein.
Topics: Acridines; Adenosine Triphosphate; Amino Acid Motifs; Amino Acid Substitution; Animals; ATP Binding Cassette Transporter, Subfamily B; Binding Sites; Biocatalysis; Dibenzocycloheptenes; HeLa Cells; Humans; Hydrogen Bonding; Hydrolysis; Lepidoptera; Ligands; Membrane Transport Modulators; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Mutant Proteins; Quinolines; Recombinant Proteins; Tetrahydroisoquinolines | 2016 |
Effects of a detergent micelle environment on P-glycoprotein (ABCB1)-ligand interactions.
Topics: Acridines; Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily B; Baculoviridae; Binding Sites; Detergents; Dibenzocycloheptenes; Drug Delivery Systems; Drug Evaluation, Preclinical; Glucosides; Humans; Hydrolysis; Inhibitory Concentration 50; Insecta; Ligands; Mice; Micelles; Peptides, Cyclic; Protein Binding; Quinolines; Tetrahydroisoquinolines; Verapamil | 2017 |
A novel fluorescence-based functional assay for human OATP1A2 and OATP1C1 identifies interaction between third-generation P-gp inhibitors and OATP1A2.
Topics: Acridines; Cell Line; Dibenzocycloheptenes; Fluorescent Dyes; Humans; Organic Anion Transporters; Quinolines; Tetrahydroisoquinolines | 2020 |
ATP-dependent thermostabilization of human P-glycoprotein (ABCB1) is blocked by modulators.
Topics: Acridines; Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily B; Calcium Channel Blockers; Cell Line; Dibenzocycloheptenes; Gene Expression Regulation; Humans; Insecta; Protein Binding; Protein Conformation; Protein Stability; Quinolines; Temperature; Tetrahydroisoquinolines; Verapamil | 2019 |