Page last updated: 2024-08-21

acridines and kw 2170

acridines has been researched along with kw 2170 in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's3 (60.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ashizawa, T; Gomi, K; Okabe, M; Shimizu, M1
Kuramitsu, T; Kuwabara, T; Ohashi, R; Takai, K1
Aiba, K; Eguchi, K; Hida, T; Horikoshi, N; Kuwabara, T; Ogawa, M; Saeki, T; Sugiura, T; Takashima, S1
Alvarez, RD; Barnes, MN; Cohn, D; Estes, JM; Leath, CA; Modiano, MR; Sawyer, M; Straughn, JM; Williams, S1
Bolger, GB; De Souza, PL; Fujimori, M; Khoo, KS; Lim, R; North, S; Phillips, J; Spiridonidis, H1

Trials

3 trial(s) available for acridines and kw 2170

ArticleYear
Phase I and pharmacokinetic study of KW-2170, a novel pyrazoloacridone compound, in patients with malignant tumors.
    Cancer chemotherapy and pharmacology, 2004, Volume: 54, Issue:5

    Topics: Acridines; Adult; Aged; Antineoplastic Agents; Area Under Curve; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Neoplasms; Pyrazoles

2004
Efficacy and toxicity of the novel chemotherapeutic agent KW-2170 in recurrent epithelial ovarian cancer.
    Gynecologic oncology, 2006, Volume: 102, Issue:2

    Topics: Acridines; Adult; Aged; Antineoplastic Agents; Female; Humans; Middle Aged; Neoplasm Recurrence, Local; Ovarian Neoplasms; Prospective Studies; Pyrazoles

2006
A phase II trial of weekly i.v. KW-2170 in advanced castrate-resistant prostate cancer.
    Asia-Pacific journal of clinical oncology, 2010, Volume: 6, Issue:4

    Topics: Acridines; Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Castration; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Pyrazoles; Quality of Life; Survival Rate; Treatment Outcome

2010

Other Studies

2 other study(ies) available for acridines and kw 2170

ArticleYear
Antitumor activity of KW-2170, a novel pyrazoloacridone derivative.
    Anti-cancer drugs, 1998, Volume: 9, Issue:3

    Topics: Acridines; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Doxorubicin; Drug Resistance, Multiple; Female; Fibrosarcoma; Gastrointestinal Neoplasms; Humans; Liver Neoplasms; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Molecular Structure; Neoplasms; Prostatic Neoplasms; Pyrazoles; Sarcoma 180; Transplantation, Heterologous; Tumor Cells, Cultured

1998
Determination of the anticancer drug KW-2170, a pyrazoloacridone derivative, and its metabolites in human and dog plasma by high-performance liquid chromatography using an electrochemical detector.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2002, Mar-05, Volume: 768, Issue:2

    Topics: Acridines; Animals; Antineoplastic Agents; Calibration; Chromatography, High Pressure Liquid; Dogs; Electrochemistry; Humans; Pyrazoles; Reproducibility of Results

2002