acridines and digoxin
acridines has been researched along with digoxin in 8 studies
Research
Studies (8)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Annaert, PP; Booth, CL; Brouwer, KL; Thakker, DR; Turncliff, RZ | 1 |
| Balimane, PV; Chong, S | 1 |
| Chiou, WL; Yao, HM | 1 |
| Asker, D; Bosquillon, C; Dolezal, P; Forbes, B; Madlova, M | 1 |
| Endo, C; Kitamura, S; Kusuhara, H; Miyajima, M; Ose, A; Sugiyama, Y; Tohyama, K | 1 |
| Amano, N; Furuta, A; Hirabayashi, H; Kimura, Y; Moriwaki, T; Sugimoto, H | 1 |
| Kallem, R; Kulkarni, CP; Mahammad, SS; Mandlekar, S; Patel, D; Singh, SP; Sinz, M; Thakur, M | 1 |
| Ahmed, Z; Bentz, J; Ellens, H; Hidalgo, IJ; Li, J; Li, L; Lumen, AA; Meng, Z; Owen, A | 1 |
Other Studies
8 other study(ies) available for acridines and digoxin
| Article | Year |
|---|---|
P-glycoprotein-mediated in vitro biliary excretion in sandwich-cultured rat hepatocytes.
Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biliary Tract; Calcium; Cell Culture Techniques; Culture Media; Dexamethasone; Digoxin; Glucocorticoids; Hepatocytes; Isoquinolines; Male; Metabolic Clearance Rate; Polystyrenes; Rats; Rats, Wistar; Rhodamine 123; Tetrahydroisoquinolines; Time Factors; Tritium | 2001 |
A combined cell based approach to identify P-glycoprotein substrates and inhibitors in a single assay.
Topics: Acridines; ATP Binding Cassette Transporter, Subfamily B; Caco-2 Cells; Cardiotonic Agents; Cell Membrane Permeability; Digoxin; Excipients; Humans; Indicators and Reagents; Reference Standards; Reproducibility of Results; Tetrahydroisoquinolines | 2005 |
The complexity of intestinal absorption and exsorption of digoxin in rats.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Digoxin; Ileum; In Vitro Techniques; Intestinal Absorption; Jejunum; Male; Microvilli; Organic Anion Transporters; Propionates; Quinidine; Quinolines; Rats; Rats, Sprague-Dawley; Sulfobromophthalein; Tetrahydroisoquinolines; Verapamil | 2006 |
In-vitro respiratory drug absorption models possess nominal functional P-glycoprotein activity.
Topics: Acridines; Administration, Inhalation; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Bronchi; Caco-2 Cells; Cells, Cultured; Digoxin; Epithelial Cells; Humans; Lung; Male; Models, Biological; Rats; Rats, Wistar; Tetrahydroisoquinolines | 2009 |
Functional characterization of mouse organic anion transporting peptide 1a4 in the uptake and efflux of drugs across the blood-brain barrier.
Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Blood-Brain Barrier; Brain; Capillaries; Cell Line; Cell Membrane; Cerebral Cortex; Choroid Plexus; Digoxin; Enkephalin, D-Penicillamine (2,5)-; Fluorobenzenes; Gene Expression; Humans; Ion Pumps; Kinetics; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Ochratoxins; Organic Anion Transporters; Organic Cation Transport Proteins; Pharmaceutical Preparations; Pravastatin; Pyrimidines; Quinolines; Recombinant Proteins; Rosuvastatin Calcium; Sulfonamides; Taurocholic Acid; Tetrahydroisoquinolines; Transfection | 2010 |
Quantitative investigation of the impact of P-glycoprotein inhibition on drug transport across blood-brain barrier in rats.
Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Brain; Cyclosporine; Digoxin; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Humans; LLC-PK1 Cells; Male; Rats; Swine; Tetrahydroisoquinolines; Up-Regulation | 2011 |
A simplified protocol employing elacridar in rodents: a screening model in drug discovery to assess P-gp mediated efflux at the blood brain barrier.
Topics: Acridines; Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Brain; Chromatography, Liquid; Cost-Benefit Analysis; Digoxin; Drug Design; Drug Interactions; Half-Life; Injections, Intravenous; Male; Mice; Propanolamines; Quinidine; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Tetrahydroisoquinolines; Time Factors; Tissue Distribution | 2012 |
Transport inhibition of digoxin using several common P-gp expressing cell lines is not necessarily reporting only on inhibitor binding to P-gp.
Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Carbamates; Cell Membrane Permeability; Cyclosporine; Digoxin; Dogs; Furans; Gene Expression; Humans; Ketoconazole; Kinetics; Loperamide; Madin Darby Canine Kidney Cells; Protein Binding; Quinidine; Sulfonamides; Tetrahydroisoquinolines; Vinblastine | 2013 |